{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T15:39:24Z","timestamp":1764603564101},"reference-count":46,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2019,3,8]],"date-time":"2019-03-08T00:00:00Z","timestamp":1552003200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2019,3,8]],"date-time":"2019-03-08T00:00:00Z","timestamp":1552003200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"funder":[{"name":"DHR NEW DELHI"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["J Gastrointest Canc"],"published-print":{"date-parts":[[2020,3]]},"DOI":"10.1007\/s12029-018-00188-4","type":"journal-article","created":{"date-parts":[[2019,3,8]],"date-time":"2019-03-08T01:51:41Z","timestamp":1552009901000},"page":"121-129","update-policy":"http:\/\/dx.doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Histopathological Examination of Gallbladder Specimens in Kumaon Region of Uttarakhand"],"prefix":"10.1007","volume":"51","author":[{"given":"Sanjeev Kumar","family":"Shukla","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Prabhat","family":"Pant","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Govind","family":"Singh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"family":"Bhuvan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K. S.","family":"Shahi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2019,3,8]]},"reference":[{"key":"188_CR1","doi-asserted-by":"publisher","first-page":"1133","DOI":"10.2169\/internalmedicine.50.5255","volume":"50","author":"K Inui","year":"2011","unstructured":"Inui K, Yoshino J, Miyoshi H. Diagnosis of gallbladder tumors. Intern Med. 2011;50:1133\u20136.","journal-title":"Intern Med"},{"key":"188_CR2","doi-asserted-by":"publisher","first-page":"657","DOI":"10.1002\/ijc.2910410503","volume":"41","author":"F Nervi","year":"1988","unstructured":"Nervi F, Duarte I, G\u00f3mez G, Rodr\u00edguez G, Pino GD, Ferrerio O, et al. Frequency of gallbladder cancer in Chile, a high-risk area. Int J Cancer. 1988;41:657\u201360.","journal-title":"Int J Cancer"},{"key":"188_CR3","first-page":"99","volume":"6","author":"R Hundal","year":"2014","unstructured":"Hundal R, Shaffer EA. Gallbladder cancer: epidemiology and outcome. Clin Epidemiol. 2014;6:99\u2013109.","journal-title":"Clin Epidemiol"},{"key":"188_CR4","doi-asserted-by":"publisher","first-page":"89","DOI":"10.1007\/s00534-012-0567-x","volume":"20","author":"Y Yamashita","year":"2013","unstructured":"Yamashita Y, Takada T, Strasberg SM, Pitt HA, Gouma DJ, Garden OJ, et al. Tokyo guideline revision committee, TG13 surgical management of acute cholecystitis. J Hepatobiliary Pancreat Sci. 2013;20:89\u201396.","journal-title":"J Hepatobiliary Pancreat Sci"},{"key":"188_CR5","first-page":"221","volume":"3","author":"M Rakic","year":"2014","unstructured":"Rakic M, Patrlj L, Kopljar M, et al. Gallbladder cancer. Hepatobiliary Surg Nutr. 2014;3:221\u20136.","journal-title":"Hepatobiliary Surg Nutr"},{"key":"188_CR6","doi-asserted-by":"publisher","first-page":"1917","DOI":"10.1007\/s10620-014-3100-z","volume":"59","author":"T Ogura","year":"2014","unstructured":"Ogura T, Kurisu Y, Masuda D, Imoto A, Onda S, Kamiyama R, et al. Can endoscopic ultrasound-guided fine needle aspiration offer clinical benefit for thick-walled gallbladders? Dig Dis Sci. 2014;59:1917\u201324.","journal-title":"Dig Dis Sci"},{"key":"188_CR7","doi-asserted-by":"publisher","first-page":"652","DOI":"10.1007\/s12094-012-0988-7","volume":"15","author":"X Yi","year":"2013","unstructured":"Yi X, Long X, Zai H, Xiao D, Li W, Li Y. Unsuspected gallbladder carcinoma discovered during or after cholecystectomy: focus on appropriate radical resection according to the T-stage. Clin Transl Oncol. 2013;15:652\u20138.","journal-title":"Clin Transl Oncol"},{"key":"188_CR8","doi-asserted-by":"publisher","first-page":"78","DOI":"10.1016\/j.crad.2013.09.017","volume":"69","author":"NK Lee","year":"2014","unstructured":"Lee NK, Kim S, Kim TU, et al. Diffusion-weighted MRI for differentiation of benign from malignant lesions in the gallbladder. Clin Radiol. 2014;69:78\u201385.","journal-title":"Clin Radiol"},{"key":"188_CR9","doi-asserted-by":"publisher","first-page":"596","DOI":"10.4293\/108680813X13693422519352","volume":"17","author":"GP Wright","year":"2013","unstructured":"Wright GP, Siripong A, Winton MD, Mitchell EJ, Goslin BJ, Chung MH. Selective laparoscopic approach in suspected gallbladder malignancy. JSLS. 2013;17:596\u2013601.","journal-title":"JSLS"},{"key":"188_CR10","doi-asserted-by":"publisher","first-page":"2561","DOI":"10.1007\/s00464-013-2787-9","volume":"27","author":"G Cwik","year":"2013","unstructured":"Cwik G, Skoczylas T, Wyroslak-Najs J, et al. The value of percutaneous ultrasound in predicting conversion from laparoscopic to open cholecystectomy due to acute cholecystitis. Surg Endosc. 2013;27:2561\u20138.","journal-title":"Surg Endosc"},{"key":"188_CR11","doi-asserted-by":"publisher","first-page":"235","DOI":"10.1097\/RCT.0b013e3182aafb6b","volume":"38","author":"CH Mitchell","year":"2014","unstructured":"Mitchell CH, Johnson PT, Fishman EK, Hruban RH, Raman SP. Features suggestive of gallbladder malignancy: analysis of T1, T2, and T3 tumors on cross-sectional imaging. J Comput Assist Tomogr. 2014;38:235\u201341.","journal-title":"J Comput Assist Tomogr"},{"key":"188_CR12","first-page":"912","volume":"49","author":"VK Shukla","year":"2008","unstructured":"Shukla VK, Chauhan VS, Mishra RN, et al. Lifestyle, reproductive factors and risk of gallbladder cancer. Singapore Med J. 2008;49:912\u20135.","journal-title":"Singapore Med J"},{"key":"188_CR13","doi-asserted-by":"publisher","first-page":"407","DOI":"10.1002\/ijc.10716","volume":"102","author":"I Serra","year":"2002","unstructured":"Serra I, Yamamoto M, Calvo A, Cavada G, B\u00e1ez S, Endoh K, et al. Association of chili pepper consumption, low socioeconomic status and longstanding gallstones with gallbladder cancer in Chilean population. Int J Cancer. 2002;102:407\u201311.","journal-title":"Int J Cancer"},{"key":"188_CR14","doi-asserted-by":"publisher","first-page":"293","DOI":"10.4103\/1947-2714.98586","volume":"4","author":"A Andren-Sandberg","year":"2012","unstructured":"Andren-Sandberg A. Diagnosis and management of gallbladder cancer. N Am J Med Sci. 2012;4:293\u20139.","journal-title":"N Am J Med Sci"},{"key":"188_CR15","first-page":"16","volume":"29","author":"BB Tyagi","year":"2008","unstructured":"Tyagi BB, Manoharan N, Raina V. Risk factors for gallbladder cancer: a population based case-control study in Delhi. Ind J Med Paed Onco. 2008;29:16\u201326.","journal-title":"Ind J Med Paed Onco"},{"key":"188_CR16","first-page":"209","volume":"16","author":"VK Kapoor","year":"2003","unstructured":"Kapoor VK, Mc Michael AJ. Gallbladder cancer: an \u2018Indian\u2019 disease. Nat Med J Ind. 2003;16:209\u201313.","journal-title":"Nat Med J Ind"},{"key":"188_CR17","first-page":"62","volume":"13","author":"K Bartosiak","year":"2018","unstructured":"Bartosiak K, Liszka M, Drazba T, Pa\u015bnik K, Janik MR. Unexpected pathological findings after laparoscopic cholecystectomy-analysis of 1131 cases. Wideochir Inne Tech Maloinwazyjne. 2018;13:62\u20136.","journal-title":"Wideochir Inne Tech Maloinwazyjne"},{"key":"188_CR18","doi-asserted-by":"publisher","first-page":"5613","DOI":"10.7314\/APJCP.2012.13.11.5613","volume":"13","author":"NH Hamdani","year":"2012","unstructured":"Hamdani NH, Qadri SK, Aggarwalla R, Bhartia VK, Chaudhuri S, Debakshi S, et al. Clinicopathological study of gallbladder carcinoma with special reference to gallstones: our 8-year experience from eastern India. Asian Pac J Cancer Prev. 2012;13:5613\u20137.","journal-title":"Asian Pac J Cancer Prev"},{"key":"188_CR19","doi-asserted-by":"publisher","first-page":"32","DOI":"10.1007\/s12664-010-0005-4","volume":"29","author":"R Mittal","year":"2010","unstructured":"Mittal R, Jesudason MR, Nayak S. Selective histopathology in cholecystectomy for gallstone disease. Indian J Gastroenterol. 2010;29:32\u20136.","journal-title":"Indian J Gastroenterol"},{"key":"188_CR20","first-page":"399","volume":"6","author":"F Tatli","year":"2017","unstructured":"Tatli F, Ozgonul A, Yucel Y, et al. Incidental gallbladder cancer at cholecystectomy. Ann Ital Chir. 2017;6:399\u2013402.","journal-title":"Ann Ital Chir"},{"key":"188_CR21","first-page":"335","volume":"48","author":"M Stancu","year":"2007","unstructured":"Stancu M, Caruntu ID, Giusca S, et al. Hyperplasia, metaplasia, dysplasia and neoplasia lesions in chronic cholecystitis - a morphologic study. Rom J Morphol Embryo. 2007;48:335\u201342.","journal-title":"Rom J Morphol Embryo"},{"key":"188_CR22","first-page":"90","volume":"12","author":"R Shrestha","year":"2010","unstructured":"Shrestha R, Tiwari M, Ranabhat SK, Aryal G, Rauniyar SK, Shrestha HG. Incidental gallbladder carcinoma: value of routine histological examination of cholecystectomy specimens. Nepal Med Coll J. 2010;12:90\u20134.","journal-title":"Nepal Med Coll J."},{"key":"188_CR23","doi-asserted-by":"publisher","first-page":"456","DOI":"10.1016\/j.hpb.2017.11.006","volume":"20","author":"H Koppatz","year":"2018","unstructured":"Koppatz H, Nordin A, Scheinin T, Sallinen V. The risk of incidental gallbladder cancer is negligible in macroscopically normal cholecystectomy specimens. HPB (Oxford). 2018;20:456\u201346.","journal-title":"HPB (Oxford)"},{"key":"188_CR24","first-page":"1","volume":"93","author":"V Talreja","year":"2016","unstructured":"Talreja V, Ali A, Khawaja R, et al. Surgically resected gall bladder: is histopathology needed for all? Surg Res Pract. 2016;93:1\u20134.","journal-title":"Surg Res Pract"},{"key":"188_CR25","doi-asserted-by":"publisher","first-page":"586","DOI":"10.1007\/s00464-016-5002-y","volume":"31","author":"SM Wrenn","year":"2017","unstructured":"Wrenn SM, Callas PW, Abu-Jaish W. Histopathological examination of specimen following cholecystectomy: are we accepting resect and discard? Surg Endosc. 2017;31:586\u201393.","journal-title":"Surg Endosc"},{"key":"188_CR26","doi-asserted-by":"publisher","first-page":"93","DOI":"10.3322\/caac.21388","volume":"67","author":"MB Amin","year":"2017","unstructured":"Amin MB, Greene FL, Edge SB, et al. The eighth edition AJCC cancer staging manual: continuing to build a bridge from a population-based to a more \u201cpersonalized\u201d approach to cancer staging. CA Cancer J Clin. 2017;67:93\u20139.","journal-title":"CA Cancer J Clin"},{"key":"188_CR27","doi-asserted-by":"publisher","first-page":"1050","DOI":"10.5455\/2320-6012.ijrms20140871","volume":"2","author":"JD Sharma","year":"2014","unstructured":"Sharma JD, Kalita I, Das T, Goswami P, Krishnatreya M. A retrospective study of post-operative gall bladder pathology with special reference to incidental carcinoma of the gall bladder. Int J Res Med Sci. 2014;2:1050\u20133.","journal-title":"Int J Res Med Sci"},{"key":"188_CR28","doi-asserted-by":"publisher","first-page":"224","DOI":"10.3126\/jpn.v2i3.6027","volume":"2","author":"R Baidya","year":"2012","unstructured":"Baidya R, Sigdel B, Baidya NL. Histopathological changes in gallbladder mucosa associated with cholelithiasis. J Pathol Nepal. 2012;2:224\u20135.","journal-title":"J Pathol Nepal"},{"key":"188_CR29","doi-asserted-by":"publisher","first-page":"201","DOI":"10.1016\/S1499-3872(15)60351-4","volume":"14","author":"HX Yuan","year":"2015","unstructured":"Yuan HX, Cao JY, Kong WT, Xia HS, Wang X, Wang WP. Contrastenhanced ultrasound in diagnosis of gallbladder adenoma. Hepatobiliary Pancreat Dis Int. 2015;14:201\u201317.","journal-title":"Hepatobiliary Pancreat Dis Int"},{"key":"188_CR30","doi-asserted-by":"publisher","first-page":"318","DOI":"10.1590\/S0104-42302010000300017","volume":"56","author":"AS Matos","year":"2010","unstructured":"Matos AS, Baptista HN, Pinheiro C, et al. Gallbladder polyps: how should they be treated and when? Rev Assoc Med Bras. 2010;56:318\u201321.","journal-title":"Rev Assoc Med Bras"},{"key":"188_CR31","doi-asserted-by":"publisher","first-page":"675","DOI":"10.1046\/j.1365-2168.2001.01749.x","volume":"88","author":"T Wakai","year":"2001","unstructured":"Wakai T, Shirai Y, Yokoyama N, Nagakura S, Watanabe H, Hatakeyama K. Early gallbladder carcinoma does not warrant radical resection. Br J Surg. 2001;88:675\u20138.","journal-title":"Br J Surg"},{"key":"188_CR32","doi-asserted-by":"publisher","first-page":"131","DOI":"10.4174\/astr.2016.90.3.131","volume":"90","author":"Y Ahn","year":"2016","unstructured":"Ahn Y, Park CS, Hwang S, Jang HJ, Choi KM, Lee SG. Incidental gallbladder cancer after routine cholecystectomy: when should we suspect it preoperatively and what are predictors of patient survival? Ann Surg Treat Res. 2016;90:131\u20138.","journal-title":"Ann Surg Treat Res"},{"key":"188_CR33","doi-asserted-by":"publisher","first-page":"143","DOI":"10.1590\/S1807-59322010000200005","volume":"65","author":"AL Meirelles-Costa","year":"2010","unstructured":"Meirelles-Costa AL, Bresciani CJ, et al. Are histological alterations observed in the gallbladder precancerous lesions? Clinics (Sao Paulo). 2010;65:143\u201350.","journal-title":"Clinics (Sao Paulo)"},{"key":"188_CR34","doi-asserted-by":"publisher","first-page":"269","DOI":"10.1111\/j.1477-2574.2012.00443.x","volume":"14","author":"AK Agarwal","year":"2012","unstructured":"Agarwal AK, Kalayarasan R, Singh S, Javed A, Sakhuja P. All cholecystectomy specimens must be sent for histopathology to detect in apparent gallbladder cancer. HPB (Oxford). 2012;14:269\u201373.","journal-title":"HPB (Oxford)"},{"key":"188_CR35","doi-asserted-by":"publisher","first-page":"695","DOI":"10.1038\/nrc1429","volume":"4","author":"II Wistuba","year":"2004","unstructured":"Wistuba II, Gazdar AF. Gallbladder cancer: lessons from a rare tumour. Nat Rev Cancer. 2004;4:695\u2013706.","journal-title":"Nat Rev Cancer"},{"key":"188_CR36","doi-asserted-by":"publisher","first-page":"172","DOI":"10.5009\/gnl.2012.6.2.172","volume":"6","author":"LM Stinton","year":"2012","unstructured":"Stinton LM, Shaffer EA. Epidemiology of gallbladder disease: cholelithiasis and cancer. Gut Liver. 2012;6:172\u201387.","journal-title":"Gut Liver"},{"key":"188_CR37","doi-asserted-by":"publisher","first-page":"632","DOI":"10.1016\/S0016-5085(99)70456-7","volume":"117","author":"JE Everhart","year":"1999","unstructured":"Everhart JE, Khare M, Hill M, Maurer KR. Prevalence and ethnic differences in gallbladder disease in the United States. Gastroenterol. 1999;117:632\u20139.","journal-title":"Gastroenterol"},{"key":"188_CR38","doi-asserted-by":"publisher","first-page":"2189","DOI":"10.1007\/s00268-009-0164-6","volume":"33","author":"V Lohsiriwat","year":"2009","unstructured":"Lohsiriwat V, Vongjirad A, Lohsiriwat D. Value of routine histopathologic examination of three common surgical specimens: appendix, gallbladder, and hemorrhoid. World J Surg. 2009;33:2189\u201393.","journal-title":"World J Surg"},{"key":"188_CR39","doi-asserted-by":"publisher","first-page":"238","DOI":"10.1308\/003588407X168361","volume":"89","author":"B Darmas","year":"2007","unstructured":"Darmas B, Mahmud S, Abbas A, Baker AL. Is there any justification for the routine histological examination of straightforward cholecystectomy specimens? Ann R Coll Surg Engl. 2007;89:238\u201341.","journal-title":"Ann R Coll Surg Engl"},{"key":"188_CR40","doi-asserted-by":"publisher","first-page":"564","DOI":"10.1007\/s00534-007-1225-6","volume":"14","author":"G Bazoua","year":"2007","unstructured":"Bazoua G, Hamza N, Lazim T. Do we need histology for a normal looking gallbladder? J Hepato-Biliary-Pancreat Surg. 2007;14:564\u20138.","journal-title":"J Hepato-Biliary-Pancreat Surg"},{"key":"188_CR41","doi-asserted-by":"publisher","first-page":"738","DOI":"10.1308\/003588407X209473","volume":"89","author":"CM Oommen","year":"2007","unstructured":"Oommen CM, Prakash A, Cooper JC. Routine histology of cholecystectomy specimens is unnecessary. Ann R Coll Surg Engl. 2007;89:738.","journal-title":"Ann R Coll Surg Engl"},{"key":"188_CR42","doi-asserted-by":"publisher","first-page":"233","DOI":"10.1016\/S1479-666X(03)80023-9","volume":"1","author":"FP Dix","year":"2003","unstructured":"Dix FP, Bruce IA, Krypcyzk A, Ravi S. A selective approach to histopathology of the gallbladder is justifiable. Surgeon. 2003;1:233\u20135.","journal-title":"Surgeon"},{"key":"188_CR43","doi-asserted-by":"publisher","first-page":"624","DOI":"10.1002\/jso.20528","volume":"93","author":"I Roa","year":"2006","unstructured":"Roa I, Ibacache G, Roa J, Araya J, de Aretxabala X, Mu\u00f1oz S. Gallstones and gallbladder cancervolume and weight of gallstones are associated with gallbladder cancer; a case-control study. J Surg Oncol. 2006;93:624\u20138.","journal-title":"J Surg Oncol"},{"key":"188_CR44","first-page":"90","volume":"12","author":"R Shrestha","year":"2010","unstructured":"Shrestha R, Tiwari M, Ranabhat SK, et al. Incidental gallbladder carcinoma: value of routine histological examination of cholecystectomy specimens. Nepal Med Coll J. 2010;12:90\u2013104.","journal-title":"Nepal Med Coll J"},{"key":"188_CR45","first-page":"4","volume":"6","author":"OR Abdel","year":"2018","unstructured":"Abdel OR, Elsayed Z, Elhalawani H. Gemcitabine-based chemotherapy for advanced biliary tract carcinomas. Cochrane Database Syst Rev. 2018;6:4.","journal-title":"Cochrane Database Syst Rev"},{"key":"188_CR46","doi-asserted-by":"publisher","first-page":"9","DOI":"10.1007\/s12029-017-0036-5","volume":"49","author":"SK Shukla","year":"2018","unstructured":"Shukla SK, Singh G, Shahi KS, Bhuvan, Pant P. Staging, treatment and future approaches of gallbladder carcinoma. J Gastrointest Cancer. 2018;49:9\u201315.","journal-title":"J Gastrointest Cancer"}],"container-title":["Journal of Gastrointestinal Cancer"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12029-018-00188-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s12029-018-00188-4\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12029-018-00188-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,8,10]],"date-time":"2021-08-10T13:19:32Z","timestamp":1628601572000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s12029-018-00188-4"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,3,8]]},"references-count":46,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2020,3]]}},"alternative-id":["188"],"URL":"https:\/\/doi.org\/10.1007\/s12029-018-00188-4","relation":{},"ISSN":["1941-6628","1941-6636"],"issn-type":[{"value":"1941-6628","type":"print"},{"value":"1941-6636","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,3,8]]},"assertion":[{"value":"8 March 2019","order":1,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with Ethical Standards"}},{"value":"The authors declare that they have no conflict of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of Interest"}}]}}