{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,18]],"date-time":"2026-10-18T08:46:34Z","timestamp":1792313194279,"version":"4.4.0"},"reference-count":29,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2025,3,13]],"date-time":"2025-03-13T00:00:00Z","timestamp":1741824000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2025,3,13]],"date-time":"2025-03-13T00:00:00Z","timestamp":1741824000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["J Gastrointest Canc"],"published-print":{"date-parts":[[2025,12]]},"DOI":"10.1007\/s12029-025-01168-1","type":"journal-article","created":{"date-parts":[[2025,3,13]],"date-time":"2025-03-13T13:41:23Z","timestamp":1741873283000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Age-Related Differences in Gastric Adenocarcinoma from 2000\u20132020: A SEER Database Analysis"],"prefix":"10.1007","volume":"56","author":[{"given":"Abdul Qahar Khan","family":"Yasinzai","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anwaar","family":"Saeed","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2025,3,13]]},"reference":[{"issue":"5","key":"1168_CR1","doi-asserted-by":"publisher","first-page":"338","DOI":"10.1038\/s41571-023-00747-0","volume":"20","author":"AP Thrift","year":"2023","unstructured":"Thrift AP, Wenker TN, El-Serag HB. Global burden of gastric cancer: epidemiological trends, risk factors, screening and prevention. Nat Rev Clin Oncol. 2023;20(5):338\u201349. https:\/\/doi.org\/10.1038\/s41571-023-00747-0.","journal-title":"Nat Rev Clin Oncol"},{"key":"1168_CR2","unstructured":"Organization WH. Global Cancer Observatory. 2024.\u00a0https:\/\/gco.iarc.fr\/en."},{"key":"1168_CR3","unstructured":"Society AC. Stomach Cancer Statistics. 2024. https:\/\/www.cancer.org\/cancer\/types\/stomach-cancer\/about\/keystatistics.html#:~:text=The%20American%20Cancer%20Society's%20estimates,6%2C490%20men%20and%204%2C390%20women)."},{"key":"1168_CR4","doi-asserted-by":"publisher","first-page":"101404","DOI":"10.1016\/j.eclinm.2022.101404","volume":"47","author":"E Morgan","year":"2022","unstructured":"Morgan E, Arnold M, Camargo MC, et al. The current and future incidence and mortality of gastric cancer in 185 countries, 2020\u201340: a population-based modelling study. EClinicalMedicine. 2022;47:101404. https:\/\/doi.org\/10.1016\/j.eclinm.2022.101404.","journal-title":"EClinicalMedicine"},{"issue":"2","key":"1168_CR5","doi-asserted-by":"publisher","first-page":"1860","DOI":"10.1002\/cam4.4997","volume":"12","author":"M Gonzalez-Pons","year":"2023","unstructured":"Gonzalez-Pons M, Torres-Cintr\u00f3n CR, Soto-Salgado M, et al. Racial\/ethnic disparities in gastric cancer: a 15-year population-based analysis. Cancer Med. 2023;12(2):1860\u20138. https:\/\/doi.org\/10.1002\/cam4.4997.","journal-title":"Cancer Med"},{"issue":"8","key":"1168_CR6","doi-asserted-by":"publisher","first-page":"1747","DOI":"10.1007\/s11605-019-04304-y","volume":"24","author":"H Li","year":"2020","unstructured":"Li H, Wei Z, Wang C, Chen W, He Y, Zhang C. Gender differences in gastric cancer survival: 99,922 cases based on the SEER database. J Gastrointest Surg. 2020;24(8):1747\u201357. https:\/\/doi.org\/10.1007\/s11605-019-04304-y.","journal-title":"J Gastrointest Surg"},{"issue":"2","key":"1168_CR7","doi-asserted-by":"publisher","first-page":"75","DOI":"10.1007\/s10120-007-0420-0","volume":"10","author":"S Tsugane","year":"2007","unstructured":"Tsugane S, Sasazuki S. Diet and the risk of gastric cancer: review of epidemiological evidence. Gastric Cancer. 2007;10(2):75\u201383. https:\/\/doi.org\/10.1007\/s10120-007-0420-0.","journal-title":"Gastric Cancer"},{"key":"1168_CR8","doi-asserted-by":"publisher","first-page":"3456264","DOI":"10.1155\/2017\/3456264","volume":"2017","author":"S Singh","year":"2017","unstructured":"Singh S, Jha HC. Status of Epstein-Barr virus coinfection with Helicobacter pylori in gastric cancer. J Oncol. 2017;2017:3456264. https:\/\/doi.org\/10.1155\/2017\/3456264.","journal-title":"J Oncol"},{"issue":"1","key":"1168_CR9","doi-asserted-by":"publisher","first-page":"7","DOI":"10.1186\/s41231-022-00111-x","volume":"7","author":"Richa","year":"2022","unstructured":"Richa, Sharma N, Sageena G. Dietary factors associated with gastric cancer - a review. Transl Med Commun. 2022;7(1):7. https:\/\/doi.org\/10.1186\/s41231-022-00111-x.","journal-title":"Transl Med Commun"},{"key":"1168_CR10","doi-asserted-by":"publisher","first-page":"31","DOI":"10.1111\/apm.1965.64.1.31","volume":"64","author":"P Lauren","year":"1965","unstructured":"Lauren P. The two histological main types of gastric carcinoma: diffuse and so-called intestinal-type carcinoma. An attempt at a histo-clinical classification. Acta Pathol Microbiol Scand. 1965;64:31\u201349. https:\/\/doi.org\/10.1111\/apm.1965.64.1.31.","journal-title":"Acta Pathol Microbiol Scand"},{"key":"1168_CR11","unstructured":"Organization WH. WHO Digestive System Tumors Classification. 2019.\u00a0https:\/\/publications.iarc.fr\/Book-And-Report-Series\/Who-Classification-Of-Tumours\/Digestive-System-Tumours-2019."},{"issue":"3\u20134","key":"1168_CR12","doi-asserted-by":"publisher","first-page":"115","DOI":"10.1159\/000456005","volume":"3","author":"Q Huang","year":"2017","unstructured":"Huang Q, Zou X. Clinicopathology of early gastric carcinoma: an update for pathologists and gastroenterologists. Gastrointest Tumors. 2017;3(3\u20134):115\u201324. https:\/\/doi.org\/10.1159\/000456005.","journal-title":"Gastrointest Tumors"},{"issue":"7517","key":"1168_CR13","doi-asserted-by":"publisher","first-page":"202","DOI":"10.1038\/nature13480","volume":"513","author":"AJ Bass","year":"2014","unstructured":"Bass AJ, Thorsson V, Shmulevich I, et al. Comprehensive molecular characterization of gastric adenocarcinoma. Nature. 2014;513(7517):202\u20139. https:\/\/doi.org\/10.1038\/nature13480.","journal-title":"Nature"},{"key":"1168_CR14","doi-asserted-by":"publisher","unstructured":"Zhang C, Miao W, Liu N, Ge R, Wang C. Radical proximal gastrectomy for gastric carcinoma. Transl Gastrointest Cancer. 2013;2(S1)65\u20138. https:\/\/doi.org\/10.3978\/j.issn.2224-4778.2013.05.21.","DOI":"10.3978\/j.issn.2224-4778.2013.05.21"},{"issue":"2","key":"1168_CR15","doi-asserted-by":"publisher","first-page":"163","DOI":"10.1023\/a:1008243606668","volume":"8","author":"B Glimelius","year":"1997","unstructured":"Glimelius B, Ekstr\u00f6m K, Hoffman K, et al. Randomized comparison between chemotherapy plus best supportive care with best supportive care in advanced gastric cancer. Ann Oncol. 1997;8(2):163\u20138. https:\/\/doi.org\/10.1023\/a:1008243606668.","journal-title":"Ann Oncol"},{"issue":"35","key":"1168_CR16","doi-asserted-by":"publisher","first-page":"5210","DOI":"10.1200\/jco.2009.26.6114","volume":"28","author":"C Schuhmacher","year":"2010","unstructured":"Schuhmacher C, Gretschel S, Lordick F, et al. Neoadjuvant chemotherapy compared with surgery alone for locally advanced cancer of the stomach and cardia: European organisation for research and treatment of cancer randomized trial 40954. J Clin Oncol. 2010;28(35):5210\u20138. https:\/\/doi.org\/10.1200\/jco.2009.26.6114.","journal-title":"J Clin Oncol"},{"issue":"5","key":"1168_CR17","doi-asserted-by":"publisher","first-page":"616","DOI":"10.1016\/s1470-2045(18)30132-3","volume":"19","author":"A Cats","year":"2018","unstructured":"Cats A, Jansen EPM, van Grieken NCT, et al. Chemotherapy versus chemoradiotherapy after surgery and preoperative chemotherapy for resectable gastric cancer (CRITICS): an international, open-label, randomised phase 3 trial. Lancet Oncol. 2018;19(5):616\u201328. https:\/\/doi.org\/10.1016\/s1470-2045(18)30132-3.","journal-title":"Lancet Oncol"},{"issue":"1","key":"1168_CR18","doi-asserted-by":"publisher","first-page":"66","DOI":"10.1093\/ije\/dyl275","volume":"36","author":"G Nagel","year":"2007","unstructured":"Nagel G, Linseisen J, Boshuizen HC, et al. Socioeconomic position and the risk of gastric and oesophageal cancer in the European Prospective Investigation into Cancer and Nutrition (EPIC-EURGAST). Int J Epidemiol. 2007;36(1):66\u201376. https:\/\/doi.org\/10.1093\/ije\/dyl275.","journal-title":"Int J Epidemiol"},{"key":"1168_CR19","unstructured":"Bureau USC. Income in the United States. 2022. https:\/\/www.census.gov\/library\/publications\/2023\/demo\/p60-279.html#:~:text=Highlights,and%20Table%20A%2D1)."},{"issue":"13","key":"1168_CR20","doi-asserted-by":"publisher","first-page":"3285","DOI":"10.1016\/j.cgh.2023.01.037","volume":"21","author":"SD Rustgi","year":"2023","unstructured":"Rustgi SD, McKinley M, McBay B, et al. Epidemiology of gastric malignancies 2000\u20132018 according to histology: a population-based analysis of incidence and temporal trends. Clin Gastroenterol Hepatol. 2023;21(13):3285-3295.e8. https:\/\/doi.org\/10.1016\/j.cgh.2023.01.037.","journal-title":"Clin Gastroenterol Hepatol"},{"key":"1168_CR21","doi-asserted-by":"publisher","first-page":"1269435","DOI":"10.1155\/2022\/1269435","volume":"2022","author":"X Luan","year":"2022","unstructured":"Luan X, Niu P, Wang W, et al. Sex disparity in patients with gastric cancer: a systematic review and meta-analysis. J Oncol. 2022;2022:1269435. https:\/\/doi.org\/10.1155\/2022\/1269435.","journal-title":"J Oncol"},{"issue":"2","key":"1168_CR22","doi-asserted-by":"publisher","first-page":"881","DOI":"10.21873\/anticanres.14021","volume":"40","author":"R Lemini","year":"2020","unstructured":"Lemini R, Jorgensen MS, Attwood K, et al. Racial disparities in outcomes among Asians with gastric cancer in the USA. Anticancer Res. 2020;40(2):881\u20139. https:\/\/doi.org\/10.21873\/anticanres.14021.","journal-title":"Anticancer Res"},{"key":"1168_CR23","doi-asserted-by":"publisher","first-page":"31","DOI":"10.1016\/j.ypmed.2013.11.004","volume":"59","author":"X Zhang","year":"2014","unstructured":"Zhang X, Holt JB, Lu H, et al. Neighborhood commuting environment and obesity in the United States: an urban\u2013rural stratified multilevel analysis. Prev Med. 2014;59:31\u20136. https:\/\/doi.org\/10.1016\/j.ypmed.2013.11.004.","journal-title":"Prev Med"},{"issue":"22","key":"1168_CR24","doi-asserted-by":"publisher","first-page":"4020","DOI":"10.1002\/cncr.28313","volume":"119","author":"Z Wang","year":"2013","unstructured":"Wang Z, Goodman M, Saba N, El-Rayes BF. Incidence and prognosis of gastroesophageal cancer in rural, urban, and metropolitan areas of the United States. Cancer. 2013;119(22):4020\u20137. https:\/\/doi.org\/10.1002\/cncr.28313.","journal-title":"Cancer"},{"key":"1168_CR25","doi-asserted-by":"publisher","first-page":"579","DOI":"10.3389\/fonc.2018.00579","volume":"8","author":"X Li","year":"2018","unstructured":"Li X, Deng Y, Tang W, et al. Urban-Rural disparity in cancer incidence, mortality, and survivals in Shanghai, China, during 2002 and 2015. Front Oncol. 2018;8:579. https:\/\/doi.org\/10.3389\/fonc.2018.00579.","journal-title":"Front Oncol"},{"issue":"1","key":"1168_CR26","doi-asserted-by":"publisher","first-page":"170","DOI":"10.1007\/s12029-020-00564-z","volume":"53","author":"S Sarkar","year":"2022","unstructured":"Sarkar S, Dauer MJ, In H. Socioeconomic disparities in gastric cancer and identification of a single SES variable for predicting risk. J Gastrointest Cancer. 2022;53(1):170\u20138. https:\/\/doi.org\/10.1007\/s12029-020-00564-z.","journal-title":"J Gastrointest Cancer"},{"issue":"10","key":"1168_CR27","doi-asserted-by":"publisher","first-page":"854","DOI":"10.1136\/jech-2012-201108","volume":"67","author":"OA Uthman","year":"2013","unstructured":"Uthman OA, Jadidi E, Moradi T. Socioeconomic position and incidence of gastric cancer: a systematic review and meta-analysis. J Epidemiol Community Health. 2013;67(10):854\u201360. https:\/\/doi.org\/10.1136\/jech-2012-201108.","journal-title":"J Epidemiol Community Health"},{"issue":"57","key":"1168_CR28","doi-asserted-by":"publisher","first-page":"97090","DOI":"10.18632\/oncotarget.21350","volume":"8","author":"X Li","year":"2017","unstructured":"Li X, Wang W, Ruan C, et al. Age-specific impact on the survival of gastric cancer patients with distant metastasis: an analysis of SEER database. Oncotarget. 2017;8(57):97090\u2013100. https:\/\/doi.org\/10.18632\/oncotarget.21350.","journal-title":"Oncotarget"},{"key":"1168_CR29","unstructured":"Raul S. Gonzalez MD. Stomach - General WHO classification. In: Debra L. Zynger MD, editors. Pathology Outlines10 December 2020.\u00a0https:\/\/www.pathologyoutlines.com\/topic\/stomachWHOclassification.html."}],"container-title":["Journal of Gastrointestinal Cancer"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12029-025-01168-1.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s12029-025-01168-1\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12029-025-01168-1.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,3,13]],"date-time":"2025-03-13T13:41:29Z","timestamp":1741873289000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s12029-025-01168-1"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,3,13]]},"references-count":29,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2025,12]]}},"alternative-id":["1168"],"URL":"https:\/\/doi.org\/10.1007\/s12029-025-01168-1","relation":{},"ISSN":["1941-6628","1941-6636"],"issn-type":[{"value":"1941-6628","type":"print"},{"value":"1941-6636","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,3,13]]},"assertion":[{"value":"5 January 2025","order":1,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"13 March 2025","order":2,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare no competing interests.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing Interests"}}],"article-number":"78"}}