{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,16]],"date-time":"2026-03-16T11:44:27Z","timestamp":1773661467752,"version":"3.50.1"},"reference-count":46,"publisher":"Springer Science and Business Media LLC","issue":"3","license":[{"start":{"date-parts":[[2012,7,31]],"date-time":"2012-07-31T00:00:00Z","timestamp":1343692800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Mol Neurosci"],"published-print":{"date-parts":[[2013,3]]},"DOI":"10.1007\/s12031-012-9858-6","type":"journal-article","created":{"date-parts":[[2012,7,30]],"date-time":"2012-07-30T17:45:51Z","timestamp":1343670351000},"page":"480-490","source":"Crossref","is-referenced-by-count":18,"title":["Protection Effect of GDNF and Neurturin on Photosensitized Crayfish Neurons and Glial Cells"],"prefix":"10.1007","volume":"49","author":[{"given":"Anatoly","family":"Uzdensky","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maxim","family":"Komandirov","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Grigory","family":"Fedorenko","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrej","family":"Lobanov","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2012,7,31]]},"reference":[{"key":"9858_CR1","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1038\/nrn812","volume":"3","author":"MS Airaksinen","year":"2002","unstructured":"Airaksinen MS, Saarma M (2002) The GDNF family: signaling, biological functions and therapeutical value. Nat Rev Neurosci 3:383\u2013394","journal-title":"Nat Rev Neurosci"},{"key":"9858_CR2","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1159\/000094087","volume":"68","author":"MS Airaksinen","year":"2006","unstructured":"Airaksinen MS, Holm L, Hatinen T (2006) Evolution of the GDNF family ligands and receptors. Brain Behav Evol 68:181\u2013190","journal-title":"Brain Behav Evol"},{"key":"9858_CR3","first-page":"59","volume":"1704","author":"RD Almeida","year":"2004","unstructured":"Almeida RD, Manada BJ, Carvalho AP, Duarte CB (2004) Intracellular signaling mechanisms in photodynamic therapy. Biochim Biophys Acta 1704:59\u201386","journal-title":"Biochim Biophys Acta"},{"key":"9858_CR4","doi-asserted-by":"crossref","first-page":"S18","DOI":"10.1038\/nrn1434","volume":"10","author":"JK Andersen","year":"2004","unstructured":"Andersen JK (2004) Oxidative stress in neurodegeneration: cause or consequence? Nat Med 10:S18\u2013S25","journal-title":"Nat Med"},{"key":"9858_CR5","doi-asserted-by":"crossref","first-page":"1329","DOI":"10.1002\/neu.480251102","volume":"25","author":"YA Barde","year":"1994","unstructured":"Barde YA (1994) Neurotrophic factors: an evolutionary perspective. J Neurobiol 25:1329\u20131333","journal-title":"J Neurobiol"},{"key":"9858_CR6","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1080\/08977190410001723308","volume":"22","author":"DK Binder","year":"2004","unstructured":"Binder DK, Scharfman HE (2004) Brain-derived neurotrophic factor. Growth Fact 22:123\u2013131","journal-title":"Growth Fact"},{"key":"9858_CR7","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1016\/S1470-2045(04)01529-3","volume":"5","author":"SB Brown","year":"2004","unstructured":"Brown SB, Brown EA, Walker I (2004) The present and future role of photodynamic therapy in cancer treatment. Lancet Oncol 5:497\u2013508","journal-title":"Lancet Oncol"},{"key":"9858_CR8","unstructured":"Buytaert E, Dewaele M, Agostinis P (2007) Molecular pathways in cell death following photodynamic therapy. In: Uzdensky AB (ed). Photodynamic therapy at the cellular level Trivandrum: Research Signpost. p 63-96"},{"key":"9858_CR9","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S1572-1000(05)00030-X","volume":"2","author":"AP Castano","year":"2005","unstructured":"Castano AP, Demidova TN, Hamblin MR (2005) Mechanisms in photodynamic therapy: part two\u2014cellular signaling, cell metabolism and modes of cell death. Photodiagn Photodyn Ther 2:1\u201323","journal-title":"Photodiagn Photodyn Ther"},{"key":"9858_CR10","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1042\/CS20050163","volume":"110","author":"MV Chao","year":"2006","unstructured":"Chao MV, Rajagopal R, Lee FS (2006) Neurotrophin signaling in health and disease. Clin Sci (Lond) 110:167\u2013173","journal-title":"Clin Sci (Lond)"},{"key":"9858_CR11","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1002\/hipo.10145","volume":"14","author":"H Cheng","year":"2004","unstructured":"Cheng H, Fu YS (2004) Ability of GDNF to diminish free radical production leads to protection against kainate-induced excitotoxicity in hippocampus. Hippocampus 14:77\u201386","journal-title":"Hippocampus"},{"key":"9858_CR12","doi-asserted-by":"crossref","first-page":"647","DOI":"10.1002\/jnr.10245","volume":"68","author":"Y Du","year":"2002","unstructured":"Du Y, Dreyfus CF (2002) Oligodendrocytes as providers of growth factors. J Neurosci Res 68:647\u2013654","journal-title":"J Neurosci Res"},{"key":"9858_CR13","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1016\/S1572-1000(05)00008-6","volume":"1","author":"MS Eljamel","year":"2004","unstructured":"Eljamel MS (2004) Brain PDD and PDT unlocking the mystery of malignant gliomas. Photodiagn Photodyn Ther 1:303\u2013310","journal-title":"Photodiagn Photodyn Ther"},{"key":"9858_CR14","doi-asserted-by":"crossref","first-page":"1409","DOI":"10.1002\/jnr.21587","volume":"86","author":"GM Fedorenko","year":"2008","unstructured":"Fedorenko GM, Uzdensky AB (2008) Dynamics of ultrastructural changes in the isolated crayfish mechanoreceptor neuron under photodynamic impact. J Neurosci Res 86:1409\u20131416","journal-title":"J Neurosci Res"},{"key":"9858_CR15","doi-asserted-by":"crossref","first-page":"477","DOI":"10.1007\/s00441-009-0825-7","volume":"337","author":"GM Fedorenko","year":"2009","unstructured":"Fedorenko GM, Uzdensky AB (2009a) Ultrastructure of neuroglial contacts in crayfish stretch receptor. Cell Tissue Res 337:477\u2013490","journal-title":"Cell Tissue Res"},{"key":"9858_CR16","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1142\/S0219635209002290","volume":"8","author":"GM Fedorenko","year":"2009","unstructured":"Fedorenko GM, Uzdensky AB (2009b) Cellular structures involved in the transport processes and neuroglial interactions in the crayfish stretch receptor. J Integr Neurosci 8:433\u2013440","journal-title":"J Integr Neurosci"},{"key":"9858_CR17","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1002\/jnr.22560","volume":"89","author":"GM Fedorenko","year":"2011","unstructured":"Fedorenko GM, Fedorenko YP, Fedorenko AG, Uzdensky AB (2011) Dynamics of ultrastructural alterations in photosensitized crayfish glial and neuronal cells: structures involved in transport processes and neuroglial interactions. J Neurosci Res 89:341\u2013351","journal-title":"J Neurosci Res"},{"key":"9858_CR18","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1085\/jgp.39.1.69","volume":"39","author":"E Florey","year":"1955","unstructured":"Florey E, Florey E (1955) Microanatomy of the abdominal stretch receptors of the crayfish (Astacus fluviatili L.). J Gen Physiol 39:69\u201385","journal-title":"J Gen Physiol"},{"key":"9858_CR19","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1016\/S1011-1344(01)00207-X","volume":"63","author":"A Girotti","year":"2001","unstructured":"Girotti A (2001) Photosensitized oxidation of membrane lipids: reaction pathways, cytotoxic effects, and cytoprotective mechanisms. J Photochem Photobiol B: Biol 63:103\u2013113","journal-title":"J Photochem Photobiol B: Biol"},{"key":"9858_CR20","doi-asserted-by":"crossref","first-page":"2746","DOI":"10.1128\/MCB.26.7.2746-2757.2006","volume":"26","author":"SM Hauck","year":"2006","unstructured":"Hauck SM, Kinkl N, Deeg CA, Swiatek DE, Lange M, Schoffmann S, Ueffing M (2006) GDNF family ligands trigger indirect neuroprotective signaling in retinal glial cells. Mol Cell Biol 26:2746\u20132757","journal-title":"Mol Cell Biol"},{"key":"9858_CR21","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1159\/000094088","volume":"68","author":"H Jarro","year":"2006","unstructured":"Jarro H, Fainzilber M (2006) Building complex brains\u2014missing pieces in an evolutionary puzzle. Brain Behav Evol 68:191\u2013195","journal-title":"Brain Behav Evol"},{"key":"9858_CR22","first-page":"79","volume":"24","author":"H Jarro","year":"2001","unstructured":"Jarro H, Beck G, Conticello SG, Fainzilber M (2001) Evolving better brains: a need for neurotrophins? TiNS 24:79\u201385","journal-title":"TiNS"},{"key":"9858_CR23","doi-asserted-by":"crossref","first-page":"495","DOI":"10.1016\/j.brainresbull.2006.02.018","volume":"69","author":"M Kolosov","year":"2006","unstructured":"Kolosov M, Uzdensky A (2006) Crayfish mechanoreceptor neuron prevents photoinduced apoptosis of satellite glial cells. Brain Res Bull 69:495\u2013500","journal-title":"Brain Res Bull"},{"key":"9858_CR24","doi-asserted-by":"crossref","first-page":"6697","DOI":"10.1523\/JNEUROSCI.17-17-06697.1997","volume":"17","author":"DM Kopp","year":"1997","unstructured":"Kopp DM, Trachtenberg JT, Thompson WJ (1997) Glial growth factor rescues Schwann cells of mechanoreceptors from denervation-induced apoptosis. J Neurosci 17:6697\u20136706","journal-title":"J Neurosci"},{"key":"9858_CR25","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1007\/978-1-60761-697-9_17","volume-title":"Phorodynamic therapy. Methods and protocols. Methods in molecular biology","author":"H Kostron","year":"2010","unstructured":"Kostron H (2010) Photodynamic diagnosis and therapy and the brain. In: Gomer CJ (ed) Phorodynamic therapy. Methods and protocols. Methods in molecular biology, vol 635. Springer, New York, pp 261\u2013280"},{"key":"9858_CR26","doi-asserted-by":"crossref","first-page":"308","DOI":"10.1007\/s12031-009-9199-2","volume":"39","author":"AV Lobanov","year":"2009","unstructured":"Lobanov AV, Uzdensky AB (2009) Protection of crayfish glial cells but not neurons from photodynamic injury by nerve growth factor. J Mol Neurosci 39:308\u2013319","journal-title":"J Mol Neurosci"},{"key":"9858_CR27","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1101\/lm.6.3.193","volume":"6","author":"S McKay","year":"1999","unstructured":"McKay S, Purcell AL, Carew TJ (1999) Regulation of synaptic function by neurotrophic factors in vertebrates and invertebrates: implications for development and learning. Learn Mem 6:193\u2013215","journal-title":"Learn Mem"},{"key":"9858_CR28","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1002\/(SICI)1098-2396(19991201)34:3<241::AID-SYN8>3.0.CO;2-E","volume":"34","author":"CJ Messer","year":"1999","unstructured":"Messer CJ, Son JH, Joh TH, Beck KD, Nestler EJ (1999) Regulation of tyrosine hydroxylase gene transcription in ventral midbrain by glial cell line-derived neurotrophic factor. Synapse 34:241\u2013243","journal-title":"Synapse"},{"key":"9858_CR29","doi-asserted-by":"crossref","first-page":"1081","DOI":"10.1083\/jcb.200508156","volume":"172","author":"TY Nakamura","year":"2006","unstructured":"Nakamura TY, Jeromin A, Smith G, Kurushima H, Koga H, Nakabeppu Y, Wakabayashi S, Nabekura J (2006) Novel role of neuronal Ca2+ sensor-1 as a survival factor up-regulated in injured neurons. J Cell Biol 172:1081\u20131091","journal-title":"J Cell Biol"},{"key":"9858_CR30","doi-asserted-by":"crossref","first-page":"3024","DOI":"10.1523\/JNEUROSCI.21-09-03024.2001","volume":"21","author":"O Nicole","year":"2001","unstructured":"Nicole O, Ali C, Docagne F, Plawinski L, MacKenzie ET, Vivien D, Buisson A (2001) Neuroprotection mediated by glial cell line-derived neurotrophic factor: involvement of a reduction of NMDA-induced calcium influx by the mitogen-activated protein kinase pathway. J Neurosci 21:3024\u20133033","journal-title":"J Neurosci"},{"key":"9858_CR31","volume-title":"Neurotrophic growth factors in the central nervous system","author":"MM Odinak","year":"2005","unstructured":"Odinak MM, Tsigan NV (2005) Neurotrophic growth factors in the central nervous system. Nauka, Sankt-Petersburg"},{"key":"9858_CR32","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1016\/j.nbd.2005.02.009","volume":"20","author":"IG Onyango","year":"2005","unstructured":"Onyango IG, Tuttle JB, Bennett JP (2005) Brain-derived growth factor and glial cell line-derived growth factor use distinct intracellular signaling pathways to protect PD cybrids from H2O2-induced neuronal death. Neurobiol Dis 20:141\u2013154","journal-title":"Neurobiol Dis"},{"key":"9858_CR33","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1016\/j.brainres.2005.11.049","volume":"1069","author":"R Pellitteri","year":"2006","unstructured":"Pellitteri R, Russo A, Stanzani S (2006) Schwann cell: a source of neurotrophic activity on cortical glutamatergic neurons in culture. Brain Res 1069:139\u2013144","journal-title":"Brain Res"},{"key":"9858_CR34","doi-asserted-by":"crossref","first-page":"2204","DOI":"10.1126\/science.287.5461.2204","volume":"287","author":"GM Rubin","year":"2000","unstructured":"Rubin GM, Yandell MD, Wortman JR et al (2000) Comparative genomics of the eukaryotes. Science 287:2204\u20132215","journal-title":"Science"},{"key":"9858_CR35","doi-asserted-by":"crossref","first-page":"292","DOI":"10.1002\/(SICI)1097-0029(19990515\/01)45:4\/5<292::AID-JEMT13>3.0.CO;2-8","volume":"45","author":"M Saarma","year":"1999","unstructured":"Saarma M, Sariola H (1999) Other neurotrophic factors: glial cell line-derived neurotrophic factor (GDNF). Microsc Res Tech 45:292\u2013302","journal-title":"Microsc Res Tech"},{"key":"9858_CR36","doi-asserted-by":"crossref","first-page":"1611","DOI":"10.1016\/j.freeradbiomed.2005.08.005","volume":"39","author":"A Saavedra","year":"2005","unstructured":"Saavedra A, Baltazar G, Carvalho CM, Duarte EP (2005) GDNF modulates HO-1 expression in substantia nigra postnatal cell cultures. Free Rad Biol Med 39:1611\u20131619","journal-title":"Free Rad Biol Med"},{"key":"9858_CR37","doi-asserted-by":"crossref","first-page":"533","DOI":"10.1016\/j.nbd.2006.04.008","volume":"23","author":"A Saavedra","year":"2006","unstructured":"Saavedra A, Baltazar G, Santos P, Carvalho CM, Duarte EP (2006) Selective injury to dopaminergic neurons up-regulates GDNF in substantia nigra postnatal cell cultures: role of neuron\u2013glia crosstalk. Neurobiol Dis 23:533\u2013542","journal-title":"Neurobiol Dis"},{"key":"9858_CR38","doi-asserted-by":"crossref","first-page":"1217","DOI":"10.1146\/annurev.neuro.24.1.1217","volume":"24","author":"MV Sofroniew","year":"2001","unstructured":"Sofroniew MV, Howe CL, Mobley WC (2001) Nerve growth factor signaling, neuroprotection, and neural repair. Annu Rev Neurosci 24:1217\u20131281","journal-title":"Annu Rev Neurosci"},{"key":"9858_CR39","doi-asserted-by":"crossref","first-page":"615","DOI":"10.1016\/j.jocn.2005.11.014","volume":"13","author":"SS Stylli","year":"2006","unstructured":"Stylli SS, Kaye AH (2006) Photodynamic therapy of cerebral glioma\u2014a review. Part I. A biological basis. J Clin Neurosci 13:615\u2013625","journal-title":"J Clin Neurosci"},{"key":"9858_CR40","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1002\/jnr.10632","volume":"73","author":"SD Ugarte","year":"2003","unstructured":"Ugarte SD, Lin E, Klann E, Zigmond MJ, Perez RG (2003) Effects of GDNF on 6-OHDA-induced death in a dopaminergic cell line: modulation by inhibitors of PI3 kinase and MEK. J Neurosci Res 73:105\u2013112","journal-title":"J Neurosci Res"},{"key":"9858_CR41","doi-asserted-by":"crossref","first-page":"55","DOI":"10.2174\/157436208783334277","volume":"3","author":"AB Uzdensky","year":"2008","unstructured":"Uzdensky AB (2008) Signal transduction and photodynamic therapy. Curr Sign Transduct Ther 3:55\u201374","journal-title":"Curr Sign Transduct Ther"},{"key":"9858_CR42","volume-title":"Cellular and molecular mechanisms of photodynamic therapy","author":"AB Uzdensky","year":"2010","unstructured":"Uzdensky AB (2010) Cellular and molecular mechanisms of photodynamic therapy. Nauka, Sankt-Petersburg"},{"key":"9858_CR43","doi-asserted-by":"crossref","first-page":"431","DOI":"10.1562\/0031-8655(2002)0760431PIOICM2.0.CO2","volume":"76","author":"AB Uzdensky","year":"2002","unstructured":"Uzdensky AB, Bragin DE, Kolosov MS, Dergacheva OY, Fedorenko GM, Zhavoronkova AA (2002) Photodynamic inactivation of isolated crayfish mechanoreceptor neuron: different death modes under different photosensitizer concentrations. Photochem Photobiol 76:431\u2013437","journal-title":"Photochem Photobiol"},{"key":"9858_CR44","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1002\/glia.20122","volume":"49","author":"A Uzdensky","year":"2005","unstructured":"Uzdensky A, Kolosov M, Bragin D, Dergacheva O, Vanzha O, Oparina L (2005) Involvement of adenylate cyclase and tyrosine kinase signaling pathways in response of crayfish stretch receptor neuron and satellite glia cell to photodynamic treatment. Glia 49:339\u2013348","journal-title":"Glia"},{"key":"9858_CR45","doi-asserted-by":"crossref","first-page":"1304","DOI":"10.1126\/science.1058040","volume":"291","author":"JC Venter","year":"2001","unstructured":"Venter JC, Adams MD, Myers EW et al (2001) The sequence of human genome. Science 291:1304\u20131351","journal-title":"Science"},{"key":"9858_CR46","doi-asserted-by":"crossref","first-page":"439","DOI":"10.1007\/978-3-211-45295-0_66","volume":"70","author":"MJ Zigmond","year":"2006","unstructured":"Zigmond MJ (2006) Triggering endogenous neuroprotective mechanisms in Parkinson's disease: studies with a cellular model. J Neural Transm Suppl 70:439\u2013442","journal-title":"J Neural Transm Suppl"}],"container-title":["Journal of Molecular Neuroscience"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s12031-012-9858-6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s12031-012-9858-6\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s12031-012-9858-6","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,1,24]],"date-time":"2022-01-24T22:00:46Z","timestamp":1643061646000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s12031-012-9858-6"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,7,31]]},"references-count":46,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2013,3]]}},"alternative-id":["9858"],"URL":"https:\/\/doi.org\/10.1007\/s12031-012-9858-6","relation":{},"ISSN":["0895-8696","1559-1166"],"issn-type":[{"value":"0895-8696","type":"print"},{"value":"1559-1166","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,7,31]]}}}