{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T01:40:25Z","timestamp":1792546825959,"version":"4.5.0"},"reference-count":67,"publisher":"Springer Science and Business Media LLC","issue":"4","license":[{"start":{"date-parts":[[2018,10,17]],"date-time":"2018-10-17T00:00:00Z","timestamp":1539734400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"funder":[{"DOI":"10.13039\/501100008257","name":"Tarbiat Modares University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100008257","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["J Mol Neurosci"],"published-print":{"date-parts":[[2018,12]]},"DOI":"10.1007\/s12031-018-1183-2","type":"journal-article","created":{"date-parts":[[2018,10,17]],"date-time":"2018-10-17T17:57:33Z","timestamp":1539799053000},"page":"524-534","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":26,"title":["Different Pain States of Trigeminal Neuralgia Make Significant Changes in the Plasma Proteome and Some Biochemical Parameters: a Preliminary Cohort Study"],"prefix":"10.1007","volume":"66","author":[{"given":"Asghar","family":"Farajzadeh","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2529-045X","authenticated-orcid":false,"given":"S. Zahra","family":"Bathaie","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jalil","family":"Arabkheradmand","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seyed Mohammad","family":"Ghodsi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Soghrat","family":"Faghihzadeh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2018,10,17]]},"reference":[{"key":"1183_CR1","doi-asserted-by":"publisher","first-page":"247054701770476","DOI":"10.1177\/2470547017704763","volume":"1","author":"Chadi G Abdallah","year":"2017","unstructured":"Abdallah, C. G., & Geha, P. (2017). Chronic pain and chronic stress: two sides of the same coin? Chronic Stress, 1, 2470547017704763","journal-title":"Chronic Stress"},{"issue":"5","key":"1183_CR2","doi-asserted-by":"publisher","first-page":"269","DOI":"10.1007\/s10787-014-0213-0","volume":"22","author":"A Ahlawat","year":"2014","unstructured":"Ahlawat A, Rana A, Goyal N, Sharma S (2014) Potential role of nitric oxide synthase isoforms in pathophysiology of neuropathic pain. Inflammopharmacology 22(5):269\u2013278. \n                    https:\/\/doi.org\/10.1007\/s10787-014-0213-0","journal-title":"Inflammopharmacology"},{"issue":"1","key":"1183_CR3","doi-asserted-by":"publisher","first-page":"102","DOI":"10.1016\/S0022-510X(98)00023-9","volume":"156","author":"Z Alam","year":"1998","unstructured":"Alam Z, Coombes N, Waring RH, Williams AC, Steventon GB (1998) Plasma levels of neuroexcitatory amino acids in patients with migraine or tension headache. J Neurol Sci 156(1):102\u2013106","journal-title":"J Neurol Sci"},{"issue":"9","key":"1183_CR4","doi-asserted-by":"publisher","first-page":"1830","DOI":"10.1093\/brain\/123.9.1830","volume":"123","author":"M Ashina","year":"2000","unstructured":"Ashina M, Bendtsen L, Jensen R, Olesen J (2000) Nitric oxide-induced headache in patients with chronic tension-type headache. Brain 123(9):1830\u20131837","journal-title":"Brain"},{"issue":"9149","key":"1183_CR5","doi-asserted-by":"publisher","first-page":"287","DOI":"10.1016\/S0140-6736(98)01079-4","volume":"353","author":"M Ashina","year":"1999","unstructured":"Ashina M, Lassen L, Bendtsen L, Jensen R, Olesen J (1999) Effect of inhibition of nitric oxide synthase on chronic tension-type headache: a randomised crossover trial. Lancet 353(9149):287\u2013289","journal-title":"Lancet"},{"issue":"1","key":"1183_CR6","doi-asserted-by":"publisher","first-page":"24","DOI":"10.1111\/j.1526-4610.2006.00294.x","volume":"46","author":"JL Bellamy","year":"2006","unstructured":"Bellamy JL, Cady RK, Durham PL (2006) Salivary levels of CGRP and VIP in rhinosinusitis and migraine patients. Headache: J Head Face Pain 46(1):24\u201333","journal-title":"Headache: J Head Face Pain"},{"key":"1183_CR7","doi-asserted-by":"publisher","first-page":"41723","DOI":"10.1038\/srep41723","volume":"7","author":"E Bellei","year":"2017","unstructured":"Bellei E, Vilella A, Monari E, Bergamini S, Tomasi A, Cuoghi A et al (2017) Serum protein changes in a rat model of chronic pain show a correlation between animal and humans. Sci Rep 7:41723","journal-title":"Sci Rep"},{"issue":"1\u20132","key":"1183_CR8","doi-asserted-by":"publisher","first-page":"248","DOI":"10.1016\/0003-2697(76)90527-3","volume":"72","author":"MM Bradford","year":"1976","unstructured":"Bradford MM (1976) A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 72(1\u20132):248\u2013254","journal-title":"Anal Biochem"},{"issue":"15","key":"1183_CR9","doi-asserted-by":"publisher","first-page":"1855","DOI":"10.1089\/ars.2013.5346","volume":"19","author":"Jes\u00fas Castro-Marrero","year":"2013","unstructured":"Castro-Marrero, J., Cordero, M. D., S\u00e1ez-Francas, N., Jimenez-Gutierrez, C., Aguilar-Montilla, F. J., Aliste, L., & Alegre-Martin, J. (2013). Could mitochondrial dysfunction be a differentiating marker between chronic fatigue syndrome and fibromyalgia? : Mary Ann Liebert, Inc. 140 Huguenot street, 3rd floor New Rochelle, NY 10801 USA","journal-title":"Antioxidants & Redox Signaling"},{"issue":"14","key":"1183_CR10","doi-asserted-by":"publisher","first-page":"1191","DOI":"10.1212\/WNL.0b013e3182a6cb72","volume":"81","author":"E Cernuda-Moroll\u00f3n","year":"2013","unstructured":"Cernuda-Moroll\u00f3n E, Larrosa D, Ram\u00f3n C, Vega J, Mart\u00ednez-Camblor P, Pascual J (2013) Interictal increase of CGRP levels in peripheral blood as a biomarker for chronic migraine. Neurology 81(14):1191\u20131196","journal-title":"Neurology"},{"issue":"6873","key":"1183_CR11","doi-asserted-by":"publisher","first-page":"793","DOI":"10.1038\/nature715","volume":"415","author":"JE Chatterton","year":"2002","unstructured":"Chatterton JE, Awobuluyi M, Premkumar LS, Takahashi H, Talantova M, Shin Y, Zhang D (2002) Excitatory glycine receptors containing the NR3 family of NMDA receptor subunits. Nature 415(6873):793\u2013798. \n                    https:\/\/doi.org\/10.1038\/nature715","journal-title":"Nature"},{"issue":"11","key":"1183_CR12","doi-asserted-by":"publisher","first-page":"2117","DOI":"10.1002\/elps.200410381","volume":"26","author":"YY Chen","year":"2005","unstructured":"Chen YY, Lin SY, Yeh YY, Hsiao HH, Wu CY, Chen ST, Wang AHJ (2005) A modified protein precipitation procedure for efficient removal of albumin from serum. Electrophoresis 26(11):2117\u20132127","journal-title":"Electrophoresis"},{"issue":"1","key":"1183_CR13","doi-asserted-by":"publisher","first-page":"33","DOI":"10.1046\/j.1468-2982.2002.00304.x","volume":"22","author":"D D'amico","year":"2002","unstructured":"D'amico D, Ferraris A, Leone M, Catania A, Carlin A, Grazzi L, Bussone G (2002) Increased plasma nitrites in migraine and cluster headache patients in interictal period: basal hyperactivity of L-arginine-NO pathway? Cephalalgia 22(1):33\u201336","journal-title":"Cephalalgia"},{"key":"1183_CR14","doi-asserted-by":"crossref","unstructured":"Dyballa, N., & Metzger, S. (2009). Fast and sensitive colloidal coomassie G-250 staining for proteins in polyacrylamide gels. J Visualized Experiments: JoVE(30)","DOI":"10.3791\/1431"},{"issue":"2","key":"1183_CR15","doi-asserted-by":"publisher","first-page":"683","DOI":"10.1016\/j.neuroscience.2010.05.016","volume":"169","author":"S Eftekhari","year":"2010","unstructured":"Eftekhari S, Salvatore CA, Calamari A, Kane SA, Tajti J, Edvinsson L (2010) Differential distribution of calcitonin gene-related peptide and its receptor components in the human trigeminal ganglion. Neuroscience 169(2):683\u2013696","journal-title":"Neuroscience"},{"issue":"10","key":"1183_CR16","doi-asserted-by":"publisher","first-page":"1582","DOI":"10.1212\/WNL.40.10.1582","volume":"40","author":"MD Ferrari","year":"1990","unstructured":"Ferrari MD, Odink J, Bos K, Malessy M, Bruyn G (1990) Neuroexcitatory plasma amino acids are elevated in migraine. Neurology 40(10):1582\u20131582","journal-title":"Neurology"},{"key":"1183_CR17","doi-asserted-by":"publisher","first-page":"337","DOI":"10.1016\/S0074-7742(09)87017-7","volume":"87","author":"CE Fleming","year":"2009","unstructured":"Fleming CE, Mar FM, Franquinho F, Sousa MM (2009) Transthyretin: an enhancer of nerve regeneration. Int Rev Neurobiol 87:337\u2013346","journal-title":"Int Rev Neurobiol"},{"issue":"2","key":"1183_CR18","doi-asserted-by":"publisher","first-page":"831","DOI":"10.1111\/j.1471-4159.2007.04828.x","volume":"103","author":"CE Fleming","year":"2007","unstructured":"Fleming CE, Saraiva MJ, Sousa MM (2007) Transthyretin enhances nerve regeneration. J Neurochem 103(2):831\u2013839","journal-title":"J Neurochem"},{"key":"1183_CR19","doi-asserted-by":"publisher","first-page":"26","DOI":"10.2174\/1876386301609010026","volume":"9","author":"DC Fritzinger","year":"2016","unstructured":"Fritzinger DC, Benjamin DE (2016) The complement system in neuropathic and postoperative pain. Open Pain J 9:26\u201337","journal-title":"Open Pain J"},{"issue":"5","key":"1183_CR20","doi-asserted-by":"publisher","first-page":"494","DOI":"10.1097\/00000542-198405000-00022","volume":"60","author":"T Fukui","year":"1984","unstructured":"Fukui T, Hameroff SR, Gandolfi AJ (1984) Alpha-1-acid glycoprotein and beta-endorphin alterations in chronic pain patients. Anesthesiology: J Am Soc Anesthesiologists 60(5):494\u2013496","journal-title":"Anesthesiology: J Am Soc Anesthesiologists"},{"issue":"1","key":"1183_CR21","doi-asserted-by":"publisher","first-page":"206","DOI":"10.1186\/s12891-016-1059-y","volume":"17","author":"B Ghafouri","year":"2016","unstructured":"Ghafouri B, Carlsson A, Holmberg S, Thelin A, Tagesson C (2016) Biomarkers of systemic inflammation in farmers with musculoskeletal disorders; a plasma proteomic study. BMC Musculoskelet Disord 17(1):206","journal-title":"BMC Musculoskelet Disord"},{"issue":"12","key":"1183_CR22","doi-asserted-by":"publisher","first-page":"3926","DOI":"10.1002\/art.37687","volume":"64","author":"TL Glover","year":"2012","unstructured":"Glover TL, Goodin BR, Horgas AL, Kindler LL, King CD, Sibille KT, Fillingim RB (2012) Vitamin D, race, and experimental pain sensitivity in older adults with knee osteoarthritis. Arthritis Rheum 64(12):3926\u20133935. \n                    https:\/\/doi.org\/10.1002\/art.37687","journal-title":"Arthritis Rheum"},{"issue":"3","key":"1183_CR23","doi-asserted-by":"publisher","first-page":"427","DOI":"10.1093\/brain\/117.3.427","volume":"117","author":"PJ Goadsby","year":"1994","unstructured":"Goadsby PJ, Edvinsson L (1994) Human in vivo evidence for trigeminovascular activation in cluster headache neuropeptide changes and effects of acute attacks therapies. Brain 117(3):427\u2013434","journal-title":"Brain"},{"issue":"S1","key":"1183_CR24","doi-asserted-by":"publisher","first-page":"S122","DOI":"10.1002\/elps.200900051","volume":"30","author":"A G\u00f6rg","year":"2009","unstructured":"G\u00f6rg A, Drews O, L\u00fcck C, Weiland F, Weiss W (2009) 2-DE with IPGs. Electrophoresis 30(S1):S122\u2013S132","journal-title":"Electrophoresis"},{"issue":"4","key":"1183_CR25","doi-asserted-by":"publisher","first-page":"441","DOI":"10.1016\/j.tripleo.2004.02.081","volume":"100","author":"BM Gratt","year":"2005","unstructured":"Gratt BM, Anbar M (2005) A pilot study of nitric oxide blood levels in patients with chronic orofacial pain. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 100(4):441\u2013448. \n                    https:\/\/doi.org\/10.1016\/j.tripleo.2004.02.081","journal-title":"Oral Surg Oral Med Oral Pathol Oral Radiol Endod"},{"issue":"1","key":"1183_CR26","doi-asserted-by":"publisher","first-page":"131","DOI":"10.1016\/0003-2697(82)90118-X","volume":"126","author":"LC Green","year":"1982","unstructured":"Green LC, Wagner DA, Glogowski J, Skipper PL, Wishnok JS, Tannenbaum SR (1982) Analysis of nitrate, nitrite, and [15N] nitrate in biological fluids. Anal Biochem 126(1):131\u2013138","journal-title":"Anal Biochem"},{"issue":"11","key":"1183_CR27","doi-asserted-by":"publisher","first-page":"1045","DOI":"10.1631\/jzus.2005.B1045","volume":"6","author":"E Gruys","year":"2005","unstructured":"Gruys E, Toussaint MJ, Niewold TA, Koopmans SJ (2005) Acute phase reaction and acute phase proteins. J Zhejiang Univ Sci B 6(11):1045\u20131056. \n                    https:\/\/doi.org\/10.1631\/jzus.2005.B1045","journal-title":"J Zhejiang Univ Sci B"},{"issue":"5","key":"1183_CR28","doi-asserted-by":"publisher","first-page":"672","DOI":"10.1016\/j.jocn.2008.08.015","volume":"16","author":"B Guldiken","year":"2009","unstructured":"Guldiken B, Demir M, Guldiken S, Turgut N, Ozkan H, Kabayel L, Tugrul A (2009) Asymmetric dimethylarginine and nitric oxide levels in migraine during the interictal period. J Clin Neurosci 16(5):672\u2013674","journal-title":"J Clin Neurosci"},{"issue":"10","key":"1183_CR29","doi-asserted-by":"publisher","first-page":"1179","DOI":"10.1177\/0333102410368444","volume":"30","author":"JM Hansen","year":"2010","unstructured":"Hansen JM, Hauge AW, Olesen J, Ashina M (2010) Calcitonin gene-related peptide triggers migraine-like attacks in patients with migraine with aura. Cephalalgia 30(10):1179\u20131186","journal-title":"Cephalalgia"},{"issue":"2","key":"1183_CR30","first-page":"226","volume":"14","author":"Z Huang","year":"2013","unstructured":"Huang Z, Ung T (2013) Effect of alpha-1-acid glycoprotein binding on pharmacokinetics and pharmacodynamics. Curr Drug Metab 14(2):226\u2013238","journal-title":"Curr Drug Metab"},{"issue":"3","key":"1183_CR31","doi-asserted-by":"publisher","first-page":"365","DOI":"10.1016\/j.neuron.2007.07.008","volume":"55","author":"T Hucho","year":"2007","unstructured":"Hucho T, Levine JD (2007) Signaling pathways in sensitization: toward a nociceptor cell biology. Neuron 55(3):365\u2013376. \n                    https:\/\/doi.org\/10.1016\/j.neuron.2007.07.008","journal-title":"Neuron"},{"key":"1183_CR32","doi-asserted-by":"publisher","first-page":"495","DOI":"10.1146\/annurev.nu.14.070194.002431","volume":"14","author":"Y Ingenbleek","year":"1994","unstructured":"Ingenbleek Y, Young V (1994) Transthyretin (prealbumin) in health and disease: nutritional implications. Annu Rev Nutr 14:495\u2013533. \n                    https:\/\/doi.org\/10.1146\/annurev.nu.14.070194.002431","journal-title":"Annu Rev Nutr"},{"issue":"1","key":"1183_CR33","doi-asserted-by":"publisher","first-page":"12","DOI":"10.1016\/j.brainres.2006.04.010","volume":"1095","author":"K Ishihama","year":"2006","unstructured":"Ishihama K, Turman JE Jr (2006) NR3 protein expression in trigeminal neurons during postnatal development. Brain Res 1095(1):12\u201316. \n                    https:\/\/doi.org\/10.1016\/j.brainres.2006.04.010","journal-title":"Brain Res"},{"issue":"3","key":"1183_CR34","doi-asserted-by":"publisher","first-page":"295","DOI":"10.1038\/clpt.1982.163","volume":"32","author":"PR Jackson","year":"1982","unstructured":"Jackson PR, Tucker GT, Woods HF (1982) Altered plasma drug binding in cancer: role of alpha 1-acid glycoprotein and albumin. Clin Pharmacol Ther 32(3):295\u2013302","journal-title":"Clin Pharmacol Ther"},{"issue":"5","key":"1183_CR35","first-page":"E5","volume":"18","author":"PJ Jannetta","year":"2005","unstructured":"Jannetta PJ, McLaughlin MR, Casey KF (2005) Technique of microvascular decompression. Technical note. Neurosurg Focus 18(5):E5","journal-title":"Neurosurg Focus"},{"issue":"3","key":"1183_CR36","doi-asserted-by":"publisher","first-page":"461","DOI":"10.1016\/j.pain.2003.09.008","volume":"106","author":"G Juhasz","year":"2003","unstructured":"Juhasz G, Zsombok T, Modos EA, Olajos S, Jakab B, Nemeth J et al (2003) NO-induced migraine attack: strong increase in plasma calcitonin gene-related peptide (CGRP) concentration and negative correlation with platelet serotonin release. Pain 106(3):461\u2013470","journal-title":"Pain"},{"issue":"1","key":"1183_CR37","doi-asserted-by":"publisher","first-page":"62","DOI":"10.1016\/j.phymed.2013.07.013","volume":"21","author":"M Karami","year":"2013","unstructured":"Karami M, Bathaie SZ, Tiraihi T, Habibi-Rezaei M, Arabkheradmand J, Faghihzadeh S (2013) Crocin improved locomotor function and mechanical behavior in the rat model of contused spinal cord injury through decreasing calcitonin gene related peptide (CGRP). Phytomedicine 21(1):62\u201367","journal-title":"Phytomedicine"},{"key":"1183_CR38","unstructured":"Kaufmann, A. M., & Price, A. V. (2017). A Pioneer of the Modern Microvascular Decompression Surgery: Peter Jannetta. from \n                    https:\/\/www.aans.org\/-\/media\/Files\/AANS\/Media\/PDFs\/Jannetta_Pioneer-of-Modern-MVD-Surgey.ashx?la=en&hash=D112CA68988BFECE916C28498FD75341369BCBA4"},{"key":"1183_CR39","doi-asserted-by":"crossref","unstructured":"Kruuse C, Iversen HK, Jansen-Olesen I, Edvinsson L, Olesen J (2009) Calcitonin gene-related peptide (CGRP) levels during glyceryl trinitrate (GTN)-induced headache in healthy volunteers. Cephalalgia","DOI":"10.1111\/j.1468-2982.2009.01963.x"},{"issue":"2","key":"1183_CR40","doi-asserted-by":"publisher","first-page":"315","DOI":"10.1007\/s00296-014-3099-7","volume":"35","author":"P Kuru","year":"2015","unstructured":"Kuru P, Akyuz G, Yagci I, Giray E (2015) Hypovitaminosis D in widespread pain: its effect on pain perception, quality of life and nerve conduction studies. Rheumatol Int 35(2):315\u2013322","journal-title":"Rheumatol Int"},{"issue":"9049","key":"1183_CR41","doi-asserted-by":"publisher","first-page":"401","DOI":"10.1016\/S0140-6736(97)80021-9","volume":"349","author":"L Lassen","year":"1997","unstructured":"Lassen L, Ashina M, Christiansen I, Ulrich V, Olesen J (1997) Nitric oxide synthase inhibition in migraine. Lancet 349(9049):401\u2013402","journal-title":"Lancet"},{"issue":"2","key":"1183_CR42","doi-asserted-by":"publisher","first-page":"174","DOI":"10.1007\/s12291-014-0435-3","volume":"30","author":"M Lodh","year":"2015","unstructured":"Lodh M, Goswami B, Mahajan RD, Sen D, Jajodia N, Roy A (2015) Assessment of vitamin D status in patients of chronic low back pain of unknown etiology. Indian J Clin Biochem 30(2):174\u2013179","journal-title":"Indian J Clin Biochem"},{"issue":"2","key":"1183_CR43","doi-asserted-by":"publisher","first-page":"329","DOI":"10.1007\/s13105-015-0389-9","volume":"71","author":"Z Luo","year":"2015","unstructured":"Luo Z, Lei H, Sun Y, Liu X, Su D-F (2015) Orosomucoid, an acute response protein with multiple modulating activities. J Physiol Biochem 71(2):329\u2013340","journal-title":"J Physiol Biochem"},{"issue":"6","key":"1183_CR44","doi-asserted-by":"publisher","first-page":"723","DOI":"10.2217\/fnl.09.50","volume":"4","author":"FM Mar","year":"2009","unstructured":"Mar FM, Franquinho F, Fleming CE, Sousa MM (2009) Transthyretin in peripheral nerve regeneration. Future Neurol 4(6):723\u2013730","journal-title":"Future Neurol"},{"issue":"9","key":"1183_CR45","doi-asserted-by":"publisher","first-page":"1411","DOI":"10.1111\/j.1526-4610.2012.02212.x","volume":"52","author":"K Messlinger","year":"2012","unstructured":"Messlinger K, Lennerz JK, Eberhardt M, Fischer MJ (2012) CGRP and NO in the trigeminal system: mechanisms and role in headache generation. Headache: J Head Face Pain 52(9):1411\u20131427","journal-title":"Headache: J Head Face Pain"},{"key":"1183_CR46","doi-asserted-by":"publisher","first-page":"289","DOI":"10.2147\/TCRM.S37592","volume":"11","author":"N Montano","year":"2015","unstructured":"Montano N, Conforti G, Di Bonaventura R, Meglio M, Fernandez E, Papacci F (2015) Advances in diagnosis and treatment of trigeminal neuralgia. Ther Clin Risk Manag 11:289","journal-title":"Ther Clin Risk Manag"},{"issue":"5060","key":"1183_CR47","doi-asserted-by":"publisher","first-page":"1217","DOI":"10.1126\/science.256.5060.1217","volume":"256","author":"H Monyer","year":"1992","unstructured":"Monyer H, Sprengel R, Schoepfer R, Herb A, Higuchi M, Lomeli H et al (1992) Heteromeric NMDA receptors: molecular and functional distinction of subtypes. Science 256(5060):1217\u20131221","journal-title":"Science"},{"key":"1183_CR48","doi-asserted-by":"publisher","first-page":"222","DOI":"10.1016\/j.brainres.2010.06.017","volume":"1348","author":"T Murakami","year":"2010","unstructured":"Murakami T, Ohsawa Y, Zhenghua L, Yamamura K-i, Sunada Y (2010) The transthyretin gene is expressed in Schwann cells of peripheral nerves. Brain Res 1348:222\u2013225","journal-title":"Brain Res"},{"issue":"4","key":"1183_CR49","doi-asserted-by":"publisher","first-page":"299","DOI":"10.5455\/GMJ-30-160373","volume":"20","author":"M Neyal","year":"2014","unstructured":"Neyal M, Geyik S, \u00c7ekmen M, Balat A, Neyal A (2014) Elevated plasma total nitrite levels may be related to migraine attacks. Gaziantep Med J 20(4):299\u2013230","journal-title":"Gaziantep Med J"},{"issue":"2","key":"1183_CR50","doi-asserted-by":"publisher","first-page":"159","DOI":"10.1016\/S0165-0327(99)00145-7","volume":"59","author":"E Nieto","year":"2000","unstructured":"Nieto E, Vieta E, Alvarez L, Torra M, Colom F, Gast\u00f3 C (2000) Alpha-1-acid glycoprotein in major depressive disorder: relationships to severity, response to treatment and imipramine plasma levels. J Affect Disord 59(2):159\u2013164","journal-title":"J Affect Disord"},{"issue":"6","key":"1183_CR51","doi-asserted-by":"publisher","first-page":"1253","DOI":"10.1378\/chest.95.6.1253","volume":"95","author":"RC Parish","year":"1989","unstructured":"Parish RC, Terrell JR, Brown WJ Jr (1989) Clinical pharmacokinetics of theophylline and levels of alpha 1-acid glycoprotein in smokeless tobacco users. Chest 95(6):1253\u20131256","journal-title":"Chest"},{"key":"1183_CR52","doi-asserted-by":"publisher","first-page":"111","DOI":"10.1016\/j.clineuro.2016.02.012","volume":"143","author":"Z-l Qin","year":"2016","unstructured":"Qin Z-l, Yang L-Q, Li N, Yue J-N, Wu B-S, Tang Y-Z, Ni J-X (2016) Clinical study of cerebrospinal fluid neuropeptides in patients with primary trigeminal neuralgia. Clin Neurol Neurosurg 143:111\u2013115","journal-title":"Clin Neurol Neurosurg"},{"issue":"9","key":"1183_CR53","doi-asserted-by":"publisher","first-page":"e207","DOI":"10.1515\/cclm-2014-0086","volume":"52","author":"V Ruggiero","year":"2014","unstructured":"Ruggiero V, Era B, Cacace E, Molin L, Corda M, Fais A, Utzeri S (2014) A preliminary study on serum proteomics in fibromyalgia syndrome. Clinical Chemistry Laboratory Medicine (CCLM) 52(9):e207\u2013e210","journal-title":"Clinical Chemistry Laboratory Medicine (CCLM)"},{"issue":"3","key":"1183_CR54","doi-asserted-by":"publisher","first-page":"257","DOI":"10.1111\/j.1468-2982.2005.01016.x","volume":"26","author":"P Sarchielli","year":"2006","unstructured":"Sarchielli P, Pini L, Zanchin G, Alberti A, Maggioni F, Rossi C et al (2006) Clinical-biochemical correlates of migraine attacks in rizatriptan responders and non-responders. Cephalalgia 26(3):257\u2013265","journal-title":"Cephalalgia"},{"issue":"20","key":"1183_CR55","doi-asserted-by":"publisher","first-page":"1839","DOI":"10.1016\/j.jchromb.2011.04.024","volume":"879","author":"A Saroha","year":"2011","unstructured":"Saroha A, Biswas S, Chatterjee BP, Das HR (2011) Altered glycosylation and expression of plasma alpha-1-acid glycoprotein and haptoglobin in rheumatoid arthritis. J Chromatogr B 879(20):1839\u20131843","journal-title":"J Chromatogr B"},{"issue":"9","key":"1183_CR56","doi-asserted-by":"publisher","first-page":"629","DOI":"10.1177\/0333102413485658","volume":"33","author":"Society, H. C. C. o. t. I. H","year":"2013","unstructured":"Society, H. C. C. o. t. I. H (2013) The international classification of headache disorders, (beta version). Cephalalgia 33(9):629\u2013808","journal-title":"Cephalalgia"},{"issue":"20","key":"1183_CR57","doi-asserted-by":"publisher","first-page":"6840","DOI":"10.1158\/1078-0432.CCR-04-0805","volume":"10","author":"A Sparreboom","year":"2004","unstructured":"Sparreboom A, Chen H, Acharya MR, Senderowicz AM, Messmann RA, Kuwabara T et al (2004) Effects of alpha1-acid glycoprotein on the clinical pharmacokinetics of 7-hydroxystaurosporine. Clin Cancer Res 10(20):6840\u20136846. \n                    https:\/\/doi.org\/10.1158\/1078-0432.CCR-04-0805","journal-title":"Clin Cancer Res"},{"issue":"18","key":"1183_CR58","doi-asserted-by":"publisher","first-page":"1148","DOI":"10.1056\/nejm198210283071813","volume":"307","author":"E Tiula","year":"1982","unstructured":"Tiula E, Neuvonen PJ (1982) Antiepileptic drugs and alpha 1-acid glycoprotein. N Engl J Med 307(18):1148. \n                    https:\/\/doi.org\/10.1056\/nejm198210283071813","journal-title":"N Engl J Med"},{"issue":"3","key":"1183_CR59","doi-asserted-by":"publisher","first-page":"153","DOI":"10.1111\/j.1533-2500.2006.00079.x","volume":"6","author":"T T\u00f6lle","year":"2006","unstructured":"T\u00f6lle T, Dukes E, Sadosky A (2006) Patient burden of trigeminal neuralgia: results from a cross-sectional survey of health state impairment and treatment patterns in six European countries. Pain Practice 6(3):153\u2013160","journal-title":"Pain Practice"},{"issue":"4","key":"1183_CR60","doi-asserted-by":"publisher","first-page":"318","DOI":"10.1080\/00207454.2017.1374959","volume":"128","author":"GM Tripathi","year":"2018","unstructured":"Tripathi GM, Kalita J, Misra UK (2018) A study of oxidative stress in migraine with special reference to prophylactic therapy. Int J Neurosci 128(4):318\u2013324","journal-title":"Int J Neurosci"},{"issue":"9","key":"1183_CR61","doi-asserted-by":"publisher","first-page":"1609","DOI":"10.1111\/pme.12454","volume":"15","author":"R Kanel von","year":"2014","unstructured":"von Kanel R, Muller-Hartmannsgruber V, Kokinogenis G, Egloff N (2014) Vitamin D and central hypersensitivity in patients with chronic pain. Pain Med 15(9):1609\u20131618. \n                    https:\/\/doi.org\/10.1111\/pme.12454","journal-title":"Pain Med"},{"issue":"9","key":"1183_CR62","doi-asserted-by":"publisher","first-page":"1609","DOI":"10.1111\/pme.12454","volume":"15","author":"R K\u00e4nel von","year":"2014","unstructured":"von K\u00e4nel R, M\u00fcller-Hartmannsgruber V, Kokinogenis G, Egloff N (2014) Vitamin D and central hypersensitivity in patients with chronic pain. Pain Med 15(9):1609\u20131618","journal-title":"Pain Med"},{"key":"1183_CR63","doi-asserted-by":"publisher","first-page":"797","DOI":"10.2147\/JPR.S128597","volume":"10","author":"K W\u00e5hl\u00e9n","year":"2017","unstructured":"W\u00e5hl\u00e9n K, Olausson P, Carlsson A, Ghafouri N, Gerdle B, Ghafouri B (2017) Systemic alterations in plasma proteins from women with chronic widespread pain compared to healthy controls: a proteomic study. J Pain Res 10:797\u2013809","journal-title":"J Pain Res"},{"issue":"2","key":"1183_CR64","doi-asserted-by":"publisher","first-page":"261","DOI":"10.1016\/j.pain.2013.10.002","volume":"155","author":"F Wepner","year":"2014","unstructured":"Wepner F, Scheuer R, Schuetz-Wieser B, Machacek P, Pieler-Bruha E, Cross HS, Friedrich M (2014) Effects of vitamin D on patients with fibromyalgia syndrome: a randomized placebo-controlled trial. Pain 155(2):261\u2013268","journal-title":"Pain"},{"key":"1183_CR65","unstructured":"Zakrzewska, J. M. (2006). Insights: facts and stories behind trigeminal neuralgia: trigeminal neuralgia association Gainesville"},{"key":"1183_CR66","doi-asserted-by":"crossref","unstructured":"Zakrzewska, J. M., & Linskey, M. E. (2014). Trigeminal neuralgia. BMJ, 348","DOI":"10.1136\/bmj.g474"},{"issue":"5","key":"1183_CR67","doi-asserted-by":"publisher","first-page":"797","DOI":"10.1016\/j.bbagen.2007.01.009","volume":"1770","author":"F Zsila","year":"2007","unstructured":"Zsila F, Iwao Y (2007) The drug binding site of human alpha1-acid glycoprotein: insight from induced circular dichroism and electronic absorption spectra. Biochim Biophys Acta 1770(5):797\u2013809. \n                    https:\/\/doi.org\/10.1016\/j.bbagen.2007.01.009","journal-title":"Biochim Biophys Acta"}],"container-title":["Journal of Molecular Neuroscience"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s12031-018-1183-2\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s12031-018-1183-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s12031-018-1183-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,10,16]],"date-time":"2019-10-16T19:05:58Z","timestamp":1571252758000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s12031-018-1183-2"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,10,17]]},"references-count":67,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2018,12]]}},"alternative-id":["1183"],"URL":"https:\/\/doi.org\/10.1007\/s12031-018-1183-2","relation":{},"ISSN":["0895-8696","1559-1166"],"issn-type":[{"value":"0895-8696","type":"print"},{"value":"1559-1166","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,10,17]]},"assertion":[{"value":"18 March 2018","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"24 September 2018","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"17 October 2018","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with Ethical Standards"}},{"value":"The authors declare that they have no conflict of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of Interest"}},{"value":"The study was conducted in accordance with the Declaration of Helsinki and approved by the ethics committee of our University. All the participants signed the informed written consent.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics statement"}}]}}