{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,2]],"date-time":"2025-05-02T10:23:37Z","timestamp":1746181417696},"reference-count":19,"publisher":"Springer Science and Business Media LLC","issue":"3","license":[{"start":{"date-parts":[[2010,5,14]],"date-time":"2010-05-14T00:00:00Z","timestamp":1273795200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Med Oncol"],"published-print":{"date-parts":[[2011,9]]},"DOI":"10.1007\/s12032-010-9538-8","type":"journal-article","created":{"date-parts":[[2010,5,13]],"date-time":"2010-05-13T17:19:50Z","timestamp":1273771190000},"page":"781-788","source":"Crossref","is-referenced-by-count":7,"title":["Sensitization of SiHa cell to gemcitabine by CD40 activation and its overexpression in cervical carcinoma"],"prefix":"10.1007","volume":"28","author":[{"given":"Qin","family":"Huang","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qiu-Xia","family":"Qu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fang","family":"Xie","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jian-Ming","family":"Hu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"You-Guo","family":"Chen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xue-Guang","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2010,5,14]]},"reference":[{"key":"9538_CR1","doi-asserted-by":"crossref","first-page":"1083","DOI":"10.1158\/1078-0432.CCR-06-1893","volume":"13","author":"RH Vonderheide","year":"2007","unstructured":"Vonderheide RH. Prospect of targeting the CD40 pathway for cancer therapy. Clin Cancer Res. 2007;13:1083\u20138.","journal-title":"Clin Cancer Res"},{"key":"9538_CR2","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1146\/annurev.immunol.22.012703.104533","volume":"22","author":"SA Quezada","year":"2004","unstructured":"Quezada SA, Jarvinen LZ, Lind EF, et al. CD40\/CD154 interactions at the interface of tolerance and immunity. Annu Rev Immunol. 2004;22:307\u201328.","journal-title":"Annu Rev Immunol"},{"key":"9538_CR3","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1097\/CJI.0b013e31818c8816","volume":"32","author":"C Chen","year":"2009","unstructured":"Chen C, Zhu YB, Qu QX, et al. CD40-activated apoptotic tumor cell-pulsed dendritic cell could potentially elicit antitumor immune response: involvement of up-regulation of B7\u2013H3 expression. J Immunother. 2009;32:29\u201335.","journal-title":"J Immunother"},{"key":"9538_CR4","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1038\/cmi.2008.4","volume":"5","author":"T Gu","year":"2008","unstructured":"Gu T, Lin M, Chen C, et al. Fine-tuned expression of programmed death 1 ligands in mature dendritic cells stimulated by CD40 ligand is critical for the induction of an efficient tumor specific immune response. Cell Mol Immunol. 2008;5:33\u20139.","journal-title":"Cell Mol Immunol"},{"key":"9538_CR5","doi-asserted-by":"crossref","first-page":"707","DOI":"10.1016\/j.ygyno.2006.10.056","volume":"104","author":"B Melichar","year":"2007","unstructured":"Melichar B, Patenia R, Gallardo S, et al. Expression of CD40 and growth-inhibitory activity of CD40 ligand in ovarian cancer cell lines. Gynecol Oncol. 2007;104:707\u201313.","journal-title":"Gynecol Oncol"},{"key":"9538_CR6","first-page":"471","volume":"18","author":"ZH Zhou","year":"1999","unstructured":"Zhou ZH, Wang JF, Wang YD, et al. An agonist anti-human CD40 monoclonal antibody that induces dendritic cell formation and maturation and inhibits proliferation of a myeloma cell line. Hybridoma. 1999;18:471\u20138.","journal-title":"Hybridoma"},{"key":"9538_CR7","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1089\/hyb.2008.0081","volume":"28","author":"QX Qu","year":"2009","unstructured":"Qu QX, Ge Y, Chen YJ, et al. Preparation and characterization of a novel chimeric antibody against human CD40 with the potential to inhibit daudi cell proliferation. Hybridoma. 2009;28:121\u20138.","journal-title":"Hybridoma"},{"key":"9538_CR8","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1097\/00125480-200103000-00004","volume":"8","author":"JT Keating","year":"2001","unstructured":"Keating JT, Ince T, Crum CP. Surrogate biomarkers of HPV infection in cervical neoplasia screening and diagnosis. Adv Anat Pathol. 2001;8:83\u201392.","journal-title":"Adv Anat Pathol"},{"key":"9538_CR9","doi-asserted-by":"crossref","first-page":"899","DOI":"10.1053\/hupa.2002.127439","volume":"33","author":"L Riethdoff","year":"2002","unstructured":"Riethdoff L, Riethdoff S, Lee KR, et al. Human papillomavirilses, expression of pl6, and early endocervical glandular neoplasia. Hum Pathol. 2002;33:899\u2013904.","journal-title":"Hum Pathol"},{"key":"9538_CR10","doi-asserted-by":"crossref","first-page":"17475","DOI":"10.1074\/jbc.M607313200","volume":"282","author":"ND Mineva","year":"2007","unstructured":"Mineva ND, Rothstein TL, Meyers JA, et al. CD40 ligand-mediated activation of the de novo RelB NF-kappaB synthesis path-way in transformed B cells promotes rescue from apoptosis. J Biol Chem. 2007;282:17475\u201385.","journal-title":"J Biol Chem"},{"key":"9538_CR11","doi-asserted-by":"crossref","first-page":"7836","DOI":"10.1073\/pnas.1231363100","volume":"100","author":"K Imadome","year":"2003","unstructured":"Imadome K, Shirakata M, Shimizu N, et al. CD40 ligand is a critical eriector of Epstein Barr virus in host cell survival and transform action. Proc Natl Acad Sci USA. 2003;100:7836\u201340.","journal-title":"Proc Natl Acad Sci USA"},{"key":"9538_CR12","doi-asserted-by":"crossref","first-page":"429","DOI":"10.1016\/j.micinf.2009.01.007","volume":"11","author":"K Imadome","year":"2009","unstructured":"Imadome K, Shimizu N, Yajima M. CD40 signaling activated by Epstein-Barr virus promotes cell survival and proliferation in gastric carcinoma-derived human epithelial cells. Microbes Infect. 2009;11:429\u201333.","journal-title":"Microbes Infect"},{"key":"9538_CR13","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1007\/s10495-005-6067-6","volume":"10","author":"ZH Zhou","year":"2005","unstructured":"Zhou ZH, Shi Q, Wang JF, et al. Sensitization of multiple myeloma and B lymphoma lines to dexamethasone and gamma-radiation-induced apoptosis by CD40 activation. Apoptosis. 2005;10:123\u201334.","journal-title":"Apoptosis"},{"key":"9538_CR14","doi-asserted-by":"crossref","first-page":"e147","DOI":"10.1371\/journal.pbio.0060147","volume":"6","author":"LP Billen","year":"2008","unstructured":"Billen LP, Kokoski CL, Lovell JF. Bcl-XL inhibits membrane permeabilization by competing with Bax. PLoS Biol. 2008;6:e147.","journal-title":"PLoS Biol"},{"key":"9538_CR15","doi-asserted-by":"crossref","first-page":"18081","DOI":"10.1073\/pnas.0808691105","volume":"105","author":"JI Fletcher","year":"2008","unstructured":"Fletcher JI, Meusburger S, Hawkins CJ. Apoptosis is triggered when prosurvival Bcl-2 proteins cannot restrain Bax. Proc Natl Acad Sci USA. 2008;105:18081\u20137.","journal-title":"Proc Natl Acad Sci USA"},{"key":"9538_CR16","doi-asserted-by":"crossref","first-page":"727","DOI":"10.1126\/science.1059108","volume":"292","author":"MC Wei","year":"2001","unstructured":"Wei MC, Zong WX, Cheng EH, et al. Proapoptotic BAX and BAK: a requisite gateway to mitochondrial dysfunction and death. Science. 2001;292:727\u201330.","journal-title":"Science"},{"key":"9538_CR17","doi-asserted-by":"crossref","first-page":"17975","DOI":"10.1073\/pnas.0506712102","volume":"102","author":"LJ Pagliari","year":"2005","unstructured":"Pagliari LJ, Kuwana T, Bonzon C, et al. The multidomain proapoptotic molecules Bax and Bak are directly activated by heat. Proc Natl Acad Sci USA. 2005;102:17975\u201380.","journal-title":"Proc Natl Acad Sci USA"},{"key":"9538_CR18","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1016\/j.ccr.2006.10.006","volume":"10","author":"M Konopleva","year":"2006","unstructured":"Konopleva M, Contractor R, Tsao T, et al. Mechanisms of apoptosis sensitivity and resistance to the BH3 mimetic ABT-737 in acute myeloid leukemia. Cancer Cell. 2006;10:375\u201388.","journal-title":"Cancer Cell"},{"key":"9538_CR19","doi-asserted-by":"crossref","first-page":"8441","DOI":"10.1038\/sj.onc.1206999","volume":"22","author":"BD Del","year":"2003","unstructured":"Del BD, Trisciuoglio D, Scarsella M, et al. Treatment of melanoma cells with a bcl-2\/bcl-xL antisense oligonucleotide induces antiangiogenicactivity. Oncogene. 2003;22:8441\u20137.","journal-title":"Oncogene"}],"container-title":["Medical Oncology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s12032-010-9538-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s12032-010-9538-8\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s12032-010-9538-8","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,6,2]],"date-time":"2019-06-02T02:22:46Z","timestamp":1559442166000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s12032-010-9538-8"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,5,14]]},"references-count":19,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2011,9]]}},"alternative-id":["9538"],"URL":"https:\/\/doi.org\/10.1007\/s12032-010-9538-8","relation":{},"ISSN":["1357-0560","1559-131X"],"issn-type":[{"value":"1357-0560","type":"print"},{"value":"1559-131X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2010,5,14]]}}}