{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,19]],"date-time":"2026-02-19T02:57:24Z","timestamp":1771469844717,"version":"3.50.1"},"reference-count":25,"publisher":"Springer Science and Business Media LLC","issue":"4","license":[{"start":{"date-parts":[[2010,7,2]],"date-time":"2010-07-02T00:00:00Z","timestamp":1278028800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Med Oncol"],"published-print":{"date-parts":[[2011,12]]},"DOI":"10.1007\/s12032-010-9612-2","type":"journal-article","created":{"date-parts":[[2010,7,1]],"date-time":"2010-07-01T12:30:56Z","timestamp":1277987456000},"page":"1163-1168","source":"Crossref","is-referenced-by-count":20,"title":["Inhibition of 4-NQO-induced F433 rat tongue carcinogenesis by oleuropein-rich extract"],"prefix":"10.1007","volume":"28","author":[{"given":"Mohammed E.","family":"Grawish","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Manal M.","family":"Zyada","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ahmed R.","family":"Zaher","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2010,7,2]]},"reference":[{"key":"9612_CR1","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1002\/ijc.1571","volume":"97","author":"P Pisani","year":"2002","unstructured":"Pisani P, Bray F, Parkin DM. Estimates of the world-wide prevalence of cancer for 25 sites in the adult population. Int J Cancer. 2002;97:72\u201381.","journal-title":"Int J Cancer"},{"issue":"Suppl","key":"9612_CR2","doi-asserted-by":"crossref","first-page":"7S","DOI":"10.14219\/jada.archive.2001.0382","volume":"32","author":"S Silverman Jr","year":"2001","unstructured":"Silverman S Jr. Demographics and occurrence of oral and pharyngeal cancers. The outcomes, the trends, the challenge. J Am Dent Assoc. 2001;32(Suppl):7S\u201311S.","journal-title":"J Am Dent Assoc"},{"key":"9612_CR3","first-page":"39","volume":"24","author":"K Wallenius","year":"1973","unstructured":"Wallenius K, Lekholm U. Oral cancer in rats induced by the water-soluble carcinogen 4-nitrochinoline N-oxide. Odontol Revy. 1973;24:39\u201348.","journal-title":"Odontol Revy"},{"key":"9612_CR4","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1093\/carcin\/12.2.329","volume":"2","author":"T Tanaka","year":"1991","unstructured":"Tanaka T, Kojima T, Okumura A, Yoshimi N, Mori H. Alterations of the nucleolar organizer regions during 4-nitroquinoline 1-oxide-induced tongue carcinogenesis in rats. Carcinogenesis. 1991;2:329\u201333.","journal-title":"Carcinogenesis"},{"key":"9612_CR5","doi-asserted-by":"crossref","first-page":"581","DOI":"10.2174\/138920008785821657","volume":"9","author":"AG Desai","year":"2008","unstructured":"Desai AG, Qazi GN, Ganju RK, El-Tamer M, Singh J, Saxena AK, Bedi YS, Taneja SC, Bhat HK. Medicinal plants and cancer chemoprevention. Curr Drug Metab. 2008;9:581\u201391.","journal-title":"Curr Drug Metab"},{"key":"9612_CR6","doi-asserted-by":"crossref","first-page":"2986","DOI":"10.1016\/j.phytochem.2007.09.014","volume":"68","author":"JC Esp\u00ecn","year":"2007","unstructured":"Esp\u00ecn JC, Garc\u00eca-Conesa MT, Tom\u00e1s-Barber\u00e1n FA. Nutraceuticals: facts and fiction. Phytochemistry. 2007;68:2986\u20133008.","journal-title":"Phytochemistry"},{"key":"9612_CR7","doi-asserted-by":"crossref","first-page":"4774","DOI":"10.1021\/jf049881+","volume":"52","author":"J Tabera","year":"2004","unstructured":"Tabera J, Guinda A, Ruiz-Rodr\u00edguez A, Se\u00f1or\u00e1ns FJ, Ib\u00e1\u00f1ez E, Albi T, Reglero G. Countercurrent supercritical fluid extraction and fractionation of high-added-value compounds from a hexane extract of olive leaves. J Agric Food Chem. 2004;52:4774\u20139.","journal-title":"J Agric Food Chem"},{"key":"9612_CR8","doi-asserted-by":"crossref","first-page":"632","DOI":"10.1111\/j.1753-4887.2009.00248.x","volume":"67","author":"SN El","year":"2009","unstructured":"El SN, Karakaya S. Olive tree (Olea europaea) leaves: potential beneficial effects on human health. Nutr Rev. 2009;67:632\u20138.","journal-title":"Nutr Rev"},{"key":"9612_CR9","doi-asserted-by":"crossref","first-page":"4934","DOI":"10.1021\/jf025540p","volume":"50","author":"R Briante","year":"2002","unstructured":"Briante R, Patumi M, Terenziani S, Bismuto E, Febbraio F, Nucci R. Olea europaea L. leaf extract and derivatives: antioxidant properties. J Agric Food Chem. 2002;50:4934\u201340.","journal-title":"J Agric Food Chem"},{"key":"9612_CR10","doi-asserted-by":"crossref","unstructured":"Hou XZ, Liu W, Fan HT, Liu B, Pang B, Xin T, Xu SC, Pang Q. Expression of hepatocyte growth factor and its receptor c-Met in human pituitary adenomas. Neuro Oncol. 2010 Mar 3. [Epub ahead of print].","DOI":"10.1093\/neuonc\/noq024"},{"key":"9612_CR11","doi-asserted-by":"crossref","first-page":"1382","DOI":"10.1200\/JCO.1999.17.5.1382","volume":"17","author":"HB Salvesen","year":"1999","unstructured":"Salvesen HB, Iversen OE, Akslen LA. Prognostic significance of angiogenesis and Ki-67, p53, and p21 expression: a population-based endometrial carcinoma study. J Clin Oncol. 1999;17:1382\u201390.","journal-title":"J Clin Oncol"},{"key":"9612_CR12","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1016\/j.cbi.2008.08.014","volume":"176","author":"H Jemai","year":"2008","unstructured":"Jemai H, Bouaziz M, Fki I, El Feki A, Sayadi S. Hypolipidimic and antioxidant activities of oleuropein and its hydrolysis derivative-rich extracts from Chemlali olive leaves. Chem Biol Interact. 2008;176:88\u201398.","journal-title":"Chem Biol Interact"},{"key":"9612_CR13","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1016\/j.canlet.2004.08.016","volume":"221","author":"K Yoshida","year":"2005","unstructured":"Yoshida K, Tanaka T, Hirose Y, Yamaguchi F, Kohno H, Toida M, Hara A, Sugie S, Shibata T, Mori H. Dietary garcinol inhibits 4-nitroquinoline 1-oxide-induced tongue carcinogenesis in rats. Cancer Lett. 2005;221:29\u201339.","journal-title":"Cancer Lett"},{"key":"9612_CR14","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1007\/s11010-006-2269-7","volume":"283","author":"A Koul","year":"2006","unstructured":"Koul A, Mukherjee N, Gangar SC. Inhibitory effects of Azadirachta indica on DMBA-induced skin carcinogenesis in Balb\/c mice. Mol Cell Biochem. 2006;283:47\u201355.","journal-title":"Mol Cell Biochem"},{"key":"9612_CR15","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1016\/0964-1955(94)00026-Z","volume":"31B","author":"T Tanaka","year":"1995","unstructured":"Tanaka T. Chemoprevention of oral carcinogenesis. Eur J Cancer B Oral Oncol. 1995;31B:3\u201315.","journal-title":"Eur J Cancer B Oral Oncol"},{"key":"9612_CR16","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1046\/j.1440-1827.2000.01058.x","volume":"50","author":"M Kitano","year":"2000","unstructured":"Kitano M. Host genes controlling the susceptibility and resistance to squamous cell carcinoma of the tongue in a rat model. Pathol Int. 2000;50:353\u201362.","journal-title":"Pathol Int"},{"key":"9612_CR17","doi-asserted-by":"crossref","first-page":"346","DOI":"10.1016\/j.clnu.2009.03.014","volume":"28","author":"D Miljkovi\u0107","year":"2009","unstructured":"Miljkovi\u0107 D, Dekanski D, Miljkovi\u0107 Z, Momcilovi\u0107 M, Mostarica-Stojkovic M. Dry olive leaf extract ameliorates experimental autoimmune encephalomyelitis. Clin Nutr. 2009;28:346\u201350.","journal-title":"Clin Nutr"},{"key":"9612_CR18","doi-asserted-by":"crossref","first-page":"1306","DOI":"10.1271\/bbb.60716","volume":"71","author":"L Abaza","year":"2007","unstructured":"Abaza L, Talorete TP, Yamada P, Kurita Y, Zarrouk M, Isoda H. Induction of growth inhibition and differentiation of human leukemia HL-60 cells by a Tunisian gerboui olive leaf extract. Biosci Biotechnol Biochem. 2007;71:1306\u201312.","journal-title":"Biosci Biotechnol Biochem"},{"key":"9612_CR19","doi-asserted-by":"crossref","first-page":"461","DOI":"10.1016\/j.ijantimicag.2008.10.026","volume":"33","author":"AN Sudjana","year":"2009","unstructured":"Sudjana AN, D\u2019Orazio C, Ryan V, Rasool N, Ng J, Islam N, Riley TV, Hammer KA. Antimicrobial activity of commercial Olea europaea (olive) leaf extract. Int J Antimicrob Agents. 2009;33:461\u20133.","journal-title":"Int J Antimicrob Agents"},{"key":"9612_CR20","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1159\/000092716","volume":"27","author":"L Lo Muzio","year":"2006","unstructured":"Lo Muzio L, Farina A, Rubini C, Coccia E, Capogreco M, Colella G, Leonardi R, Campisi G, Carinci F. Effect of c-Met expression on survival in head and neck squamous cell carcinoma. Tumour Biol. 2006;27:115\u201321.","journal-title":"Tumour Biol"},{"key":"9612_CR21","doi-asserted-by":"crossref","first-page":"7704","DOI":"10.1021\/jf020749o","volume":"50","author":"V Lavelli","year":"2002","unstructured":"Lavelli V. Comparison of the antioxidant activities of extra virgin olive oils. J Agric Food Chem. 2002;50:7704\u20138.","journal-title":"J Agric Food Chem"},{"key":"9612_CR22","doi-asserted-by":"crossref","first-page":"2169","DOI":"10.1161\/01.CIR.102.18.2169","volume":"102","author":"F Visioli","year":"2000","unstructured":"Visioli F, Galli C, Plasmati E, Viappiani S, Hernandez A, Colombo C, Sala A. Olive phenol hydroxytyrosol prevents passive smoking-induced oxidative stress. Circulation. 2000;102:2169\u201371.","journal-title":"Circulation"},{"key":"9612_CR23","doi-asserted-by":"crossref","first-page":"769","DOI":"10.1016\/j.bbrc.2005.06.161","volume":"334","author":"HK Hamdi","year":"2005","unstructured":"Hamdi HK, Castellon R. Oleuropein, a non-toxic olive iridoid, is an anti-tumor agent and cytoskeleton disruptor. Biochem Biophys Res Commun. 2005;334:769\u201378.","journal-title":"Biochem Biophys Res Commun"},{"key":"9612_CR24","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1007\/s10616-009-9191-2","volume":"59","author":"J Han","year":"2009","unstructured":"Han J, Talorete TP, Yamada P, Isoda H. Anti-proliferative and apoptotic effects of oleuropein and hydroxytyrosol on human breast cancer MCF-7 cells. Cytotechnology. 2009;59:45\u201353.","journal-title":"Cytotechnology"},{"key":"9612_CR25","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1016\/S0271-5317(00)00288-8","volume":"21","author":"L Wlodek","year":"2001","unstructured":"Wlodek L, Steven HZ. Antioxidants, programmed cell death, and cancer. Nutr Res. 2001;21:295\u2013307.","journal-title":"Nutr Res"}],"container-title":["Medical Oncology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s12032-010-9612-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s12032-010-9612-2\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s12032-010-9612-2","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,6,1]],"date-time":"2019-06-01T22:22:48Z","timestamp":1559427768000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s12032-010-9612-2"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,7,2]]},"references-count":25,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2011,12]]}},"alternative-id":["9612"],"URL":"https:\/\/doi.org\/10.1007\/s12032-010-9612-2","relation":{},"ISSN":["1357-0560","1559-131X"],"issn-type":[{"value":"1357-0560","type":"print"},{"value":"1559-131X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2010,7,2]]}}}