{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T15:51:32Z","timestamp":1791993092051,"version":"4.4.0"},"reference-count":43,"publisher":"Springer Science and Business Media LLC","issue":"2","license":[{"start":{"date-parts":[[2023,1,6]],"date-time":"2023-01-06T00:00:00Z","timestamp":1672963200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2023,1,6]],"date-time":"2023-01-06T00:00:00Z","timestamp":1672963200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"funder":[{"DOI":"10.13039\/501100004484","name":"Tehran University of Medical Sciences and Health Services","doi-asserted-by":"publisher","award":["34686"],"award-info":[{"award-number":["34686"]}],"id":[{"id":"10.13039\/501100004484","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Med Oncol"],"DOI":"10.1007\/s12032-022-01935-1","type":"journal-article","created":{"date-parts":[[2023,1,6]],"date-time":"2023-01-06T19:03:47Z","timestamp":1673031827000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["Breast tumor metastasis following filgrastim administration due to the SDF-1\/CXCR4 pathway"],"prefix":"10.1007","volume":"40","author":[{"given":"Solmaz","family":"Khalighfard","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vahid","family":"Khori","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ebrahim","family":"Esmati","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Farahnazsadat","family":"Ahmadi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Taghi","family":"Amiriani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amirhoushang","family":"Poorkhani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Somayeh","family":"Sadani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Saeed","family":"Khodayari","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hamid","family":"Khodayari","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohammad Reza","family":"Kalhori","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pedram","family":"Keshavarz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1147-3335","authenticated-orcid":false,"given":"Ali Mohammad","family":"Alizadeh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2023,1,6]]},"reference":[{"issue":"4","key":"1935_CR1","doi-asserted-by":"publisher","first-page":"1341","DOI":"10.4049\/jimmunol.1500861","volume":"195","author":"HM Mehta","year":"2015","unstructured":"Mehta HM, Malandra M, Corey SJ. G-csf and gm-csf in neutropenia. J Immunol. 2015;195(4):1341\u20139. https:\/\/doi.org\/10.4049\/jimmunol.1500861.","journal-title":"J Immunol"},{"issue":"5","key":"1935_CR2","doi-asserted-by":"publisher","first-page":"1041","DOI":"10.1038\/leu.2013.321","volume":"28","author":"H Mehta","year":"2014","unstructured":"Mehta H, Futami M, Glaubach T, Lee D, Andolina J, Yang Q, Whichard Z, Quinn M, Lu H, Kao W. Alternatively spliced, truncated GCSF receptor promotes leukemogenic properties and sensitivity to JAK inhibition. Leukemia. 2014;28(5):1041\u201351. https:\/\/doi.org\/10.1038\/leu.2013.321.","journal-title":"Leukemia"},{"issue":"11","key":"1935_CR3","doi-asserted-by":"publisher","first-page":"2927","DOI":"10.1158\/1078-0432.CCR-09-2329","volume":"16","author":"BA Teicher","year":"2010","unstructured":"Teicher BA, Fricker SP. CXCL12 (SDF-1)\/CXCR4 pathway in cancer. Clin Cancer Res. 2010;16(11):2927\u201331. https:\/\/doi.org\/10.1158\/1078-0432.CCR-09-2329.","journal-title":"Clin Cancer Res"},{"issue":"2","key":"1935_CR4","doi-asserted-by":"publisher","first-page":"81","DOI":"10.1016\/j.it.2012.08.006","volume":"34","author":"JA Hamilton","year":"2013","unstructured":"Hamilton JA, Achuthan A. Colony stimulating factors and myeloid cell biology in health and disease. Trends Immunol. 2013;34(2):81\u20139. https:\/\/doi.org\/10.1016\/j.it.2012.08.006.","journal-title":"Trends Immunol"},{"issue":"4","key":"1935_CR5","doi-asserted-by":"publisher","first-page":"413","DOI":"10.1016\/s1074-7613(02)00424-7","volume":"17","author":"CL Semerad","year":"2002","unstructured":"Semerad CL, Liu F, Gregory AD, Stumpf K, Link DC. G-CSF is an essential regulator of neutrophil trafficking from the bone marrow to the blood. Immunity. 2002;17(4):413\u201323. https:\/\/doi.org\/10.1016\/s1074-7613(02)00424-7.","journal-title":"Immunity"},{"issue":"7","key":"1935_CR6","doi-asserted-by":"publisher","first-page":"687","DOI":"10.1038\/ni813","volume":"3","author":"I Petit","year":"2002","unstructured":"Petit I, Szyper-Kravitz M, Nagler A, Lahav M, Peled A, Habler L, Ponomaryov T, Taichman RS, Arenzana-Seisdedos F, Fujii N, Sandbank J, Zipori D, Lapidot T. G-CSF induces stem cell mobilization by decreasing bone marrow SDF-1 and up-regulating CXCR4. Nat Immunol. 2002;3(7):687\u201394. https:\/\/doi.org\/10.1038\/ni813.","journal-title":"Nat Immunol"},{"issue":"7","key":"1935_CR7","doi-asserted-by":"publisher","first-page":"879","DOI":"10.1634\/stemcells.2004-0342","volume":"23","author":"M Kucia","year":"2005","unstructured":"Kucia M, Reca R, Miekus K, Wanzeck J, Wojakowski W, Janowska-Wieczorek A, Ratajczak J, Ratajczak MZ. Trafficking of normal stem cells and metastasis of cancer stem cells involve similar mechanisms: pivotal role of the SDF-1-CXCR4 axis. Stem Cells. 2005;23(7):879\u201394. https:\/\/doi.org\/10.1634\/stemcells.2004-0342.","journal-title":"Stem Cells"},{"issue":"17","key":"1935_CR8","doi-asserted-by":"publisher","first-page":"4530","DOI":"10.1182\/blood-2011-06-318220","volume":"118","author":"LB To","year":"2011","unstructured":"To LB, Levesque J-P, Herbert KE. How I treat patients who mobilize hematopoietic stem cells poorly. Blood. 2011;118(17):4530\u201340. https:\/\/doi.org\/10.1182\/blood-2011-06-318220.","journal-title":"Blood"},{"issue":"3","key":"1935_CR9","doi-asserted-by":"publisher","first-page":"636","DOI":"10.1182\/blood.V83.3.636.636","volume":"83","author":"W Brugger","year":"1994","unstructured":"Brugger W, Bross KJ, Glatt M, Weber F, Mertelsmann R, Kanz L. Mobilization of tumor cells and hematopoietic progenitor cells into peripheral blood of patients with solid tumors. Blood. 1994;83(3):636\u201340. https:\/\/doi.org\/10.1182\/blood.V83.3.636.636.","journal-title":"Blood"},{"issue":"8","key":"1935_CR10","doi-asserted-by":"publisher","first-page":"765","DOI":"10.1158\/2326-6066.CIR-13-0190","volume":"2","author":"A Swierczak","year":"2014","unstructured":"Swierczak A, Cook AD, Lenzo JC, Restall CM, Doherty JP, Anderson RL, Hamilton JA. The promotion of breast cancer metastasis caused by inhibition of CSF-1R\/CSF-1 signaling is blocked by targeting the G-CSF receptor. Cancer Immunol Res. 2014;2(8):765\u201376. https:\/\/doi.org\/10.1158\/2326-6066.CIR-13-0190.","journal-title":"Cancer Immunol Res"},{"issue":"1","key":"1935_CR11","doi-asserted-by":"publisher","first-page":"65","DOI":"10.1016\/j.canlet.2009.02.005","volume":"280","author":"A Krohn","year":"2006","unstructured":"Krohn A, Song Y-H, Muehlberg F, Droll L, Beckmann C, Alt E. CXCR4 receptor positive spheroid forming cells are responsible for tumor invasion in vitro. Cancer lett. 2006;280(1):65\u201371. https:\/\/doi.org\/10.1016\/j.canlet.2009.02.005.","journal-title":"Cancer lett"},{"key":"1935_CR12","doi-asserted-by":"publisher","first-page":"295","DOI":"10.1016\/s0076-6879(00)25451-7","volume":"325","author":"F Michiels","year":"2000","unstructured":"Michiels F, Van Der Kammen RA, Janssen L, Nolan G, Collard JG. Expression of Rho GTPases using retroviral vectors. Methods Enzymol. 2000;325:295\u2013302. https:\/\/doi.org\/10.1016\/s0076-6879(00)25451-7.","journal-title":"Methods Enzymol"},{"issue":"12","key":"1935_CR13","doi-asserted-by":"publisher","first-page":"1405","DOI":"10.1089\/hum.1996.7.12-1405","volume":"7","author":"TM Kinsella","year":"1996","unstructured":"Kinsella TM, Nolan GP. Episomal vectors rapidly and stably produce high-titer recombinant retrovirus. Hum Gene Ther. 1996;7(12):1405\u201313. https:\/\/doi.org\/10.1089\/hum.1996.7.12-1405.","journal-title":"Hum Gene Ther"},{"issue":"2","key":"1935_CR14","doi-asserted-by":"publisher","first-page":"269","DOI":"10.1172\/JCI11330","volume":"108","author":"IS Zeelenberg","year":"2001","unstructured":"Zeelenberg IS, Ruuls-Van Stalle L, Roos E. Retention of CXCR4 in the endoplasmic reticulum blocks dissemination of a T cell hybridoma. J Clin Invest. 2001;108(2):269\u201377. https:\/\/doi.org\/10.1172\/JCI11330.","journal-title":"J Clin Invest"},{"key":"1935_CR15","doi-asserted-by":"publisher","first-page":"54","DOI":"10.1016\/j.peptides","volume":"107","author":"V Khori","year":"2018","unstructured":"Khori V, Alizadeh AM, Khalighfard S, Heidarian Y, Khodayari H. Oxytocin effects on the inhibition of the NF-\u03baB\/miR195 pathway in mice breast cancer. Peptides. 2018;107:54\u201360. https:\/\/doi.org\/10.1016\/j.peptides.","journal-title":"Peptides"},{"issue":"8","key":"1935_CR16","doi-asserted-by":"publisher","first-page":"462","DOI":"10.1179\/1607845414Y.0000000220","volume":"20","author":"F Saba","year":"2015","unstructured":"Saba F, Soleimani M, Kaviani S, Abroun S, Sayyadipoor F, Behrouz S, Saki N. G-CSF induces up-regulation of CXCR4 expression in human hematopoietic stem cells by beta-adrenergic agonist. Hematology. 2015;20(8):462\u20138. https:\/\/doi.org\/10.1179\/1607845414Y.0000000220.","journal-title":"Hematology"},{"issue":"6","key":"1935_CR17","first-page":"3217","volume":"36","author":"U Andergassen","year":"2016","unstructured":"Andergassen U, Vogl A, Mumm J-N, Koelbl AC, Hutter S, Rack B, Friese K, Jeschke U. Immunocytochemical characterization of disseminated tumour cells from bone marrow of breast cancer patients. Anticancer Res. 2016;36(6):3217\u201322.","journal-title":"Anticancer Res"},{"issue":"1","key":"1935_CR18","doi-asserted-by":"publisher","first-page":"147","DOI":"10.3892\/or.2015.3977","volume":"34","author":"JS Kim","year":"2015","unstructured":"Kim JS, Son Y, Bae MJ, Lee M, Lee CG, Jo WS, Kim SD, Yang K. Administration of granulocyte colony-stimulating factor with radiotherapy promotes tumor growth by stimulating vascularization in tumor-bearing mice. Oncol Rep. 2015;34(1):147\u201354. https:\/\/doi.org\/10.3892\/or.2015.3977.","journal-title":"Oncol Rep"},{"issue":"1","key":"1935_CR19","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1038\/s41598-020-58605-3","volume":"10","author":"M Soleymani","year":"2020","unstructured":"Soleymani M, Khalighfard S, Khodayari S, Khodayari H, Kalhori MR, Hadjighassem MR, Shaterabadi Z, Alizadeh AM. Effects of multiple injections on the efficacy and cytotoxicity of folate-targeted magnetite nanoparticles as theranostic agents for MRI detection and magnetic hyperthermia therapy of tumor cells. Sci Rep. 2020;10(1):1\u201314. https:\/\/doi.org\/10.1038\/s41598-020-58605-3.","journal-title":"Sci Rep"},{"issue":"1","key":"1935_CR20","doi-asserted-by":"publisher","first-page":"37","DOI":"10.1634\/stemcells.19-1-37","volume":"19","author":"Y Gazitt","year":"2001","unstructured":"Gazitt Y, Liu Q. Plasma levels of SDF-1 and expression of SDF-1 receptor on CD34+ cells in mobilized peripheral blood of non-Hodgkin\u2019s lymphoma patients. Stem cells. 2001;19(1):37\u201345. https:\/\/doi.org\/10.1634\/stemcells.19-1-37.","journal-title":"Stem cells"},{"issue":"1","key":"1935_CR21","first-page":"18","volume":"18","author":"AM Alizadeh","year":"2015","unstructured":"Alizadeh AM, Afrouzan H, Dinparast-Djadid N, Sawaya ACF, Azizian S, Hemmati HR, Mohagheghi MA, Erfani S. Chemoprotection of MNNG-initiated gastric cancer in rats using Iranian propolis. Arch Iran Med. 2015;18(1):18\u201323.","journal-title":"Arch Iran Med"},{"issue":"3","key":"1935_CR22","doi-asserted-by":"publisher","first-page":"164","DOI":"10.1056\/NEJM199107183250305","volume":"325","author":"J Crawford","year":"1991","unstructured":"Crawford J, Ozer H, Stoller R, Johnson D, Lyman G, Tabbara I, Kris M, Grous J, Picozzi V, Rausch G. Reduction by granulocyte colony-stimulating factor of fever and neutropenia induced by chemotherapy in patients with small-cell lung cancer. N Engl J Med. 1991;325(3):164\u201370. https:\/\/doi.org\/10.1056\/NEJM199107183250305.","journal-title":"N Engl J Med"},{"issue":"1\u20133","key":"1935_CR23","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.ejphar.2013.09.015","volume":"718","author":"M Mohsenikia","year":"2013","unstructured":"Mohsenikia M, Alizadeh AM, Khodayari S, Khodayari H, Karimi A, Zamani M, Azizian S, Mohagheghi MA. The protective and therapeutic effects of alpha-solanine on mice breast cancer. Eur J Pharmacol. 2013;718(1\u20133):1\u20139. https:\/\/doi.org\/10.1016\/j.ejphar.2013.09.015.","journal-title":"Eur J Pharmacol"},{"issue":"8","key":"1935_CR24","doi-asserted-by":"publisher","first-page":"651","DOI":"10.1038\/sj.bmt.1703901","volume":"31","author":"T Kozuka","year":"2003","unstructured":"Kozuka T, Ishimaru F, Fujii K, Masuda K, Kaneda K, Imai T, Fujii N, Ishikura H, Hongo S, Watanabe T. Plasma stromal cell-derived factor-1 during granulocyte colony-stimulating factor-induced peripheral blood stem cell mobilization. Bone Marrow Transplant. 2003;31(8):651\u20134. https:\/\/doi.org\/10.1038\/sj.bmt.1703901.","journal-title":"Bone Marrow Transplant"},{"issue":"3","key":"1935_CR25","doi-asserted-by":"publisher","first-page":"266","DOI":"10.1016\/j.stem.2013.02.004","volume":"12","author":"AJ Bass","year":"2013","unstructured":"Bass AJ, Wang TC. An inflammatory situation: SOX2 and STAT3 cooperate in squamous cell carcinoma initiation. Cell Stem Cell. 2013;12(3):266\u20138. https:\/\/doi.org\/10.1016\/j.stem.2013.02.004.","journal-title":"Cell Stem Cell"},{"issue":"6","key":"1935_CR26","doi-asserted-by":"publisher","first-page":"688","DOI":"10.1158\/2159-8290.CD-13-0593","volume":"4","author":"S Baumgart","year":"2014","unstructured":"Baumgart S, Chen N-M, Siveke JT, K\u00f6nig A, Zhang J-S, Singh SK, Wolf E, Bartkuhn M, Esposito I, He\u00dfmann E. Inflammation-Induced NFATc1\u2013STAT3 transcription complex promotes pancreatic cancer initiation by KrasG12D. Cancer Discov. 2014;4(6):688\u2013701. https:\/\/doi.org\/10.1158\/2159-8290.CD-13-0593.","journal-title":"Cancer Discov"},{"issue":"5","key":"1935_CR27","doi-asserted-by":"publisher","first-page":"1089","DOI":"10.1084\/jem.20081605","volume":"206","author":"Y Kubota","year":"2009","unstructured":"Kubota Y, Takubo K, Shimizu T, Ohno H, Kishi K, Shibuya M, Saya H, Suda T. M-CSF inhibition selectively targets pathological angiogenesis and lymphangiogenesis. J Exp Med. 2009;206(5):1089\u2013102. https:\/\/doi.org\/10.1084\/jem.20081605.","journal-title":"J Exp Med"},{"issue":"9","key":"1935_CR28","doi-asserted-by":"publisher","first-page":"e73310","DOI":"10.1371\/journal.pone.0073310","volume":"8","author":"L Fend","year":"2013","unstructured":"Fend L, Accart N, Kintz J, Cochin S, Reymann C, Le Pogam F, Marchand J-B, Menguy T, Slos P, Rooke R. Therapeutic effects of anti-CD115 monoclonal antibody in mouse cancer models through dual inhibition of tumor-associated macrophages and osteoclasts. PloS one. 2013;8(9):e73310. https:\/\/doi.org\/10.1371\/journal.pone.0073310.","journal-title":"PloS one"},{"issue":"15","key":"1935_CR29","doi-asserted-by":"publisher","first-page":"6139","DOI":"10.1158\/0008-5472.CAN-10-0706","volume":"70","author":"HH Yan","year":"2010","unstructured":"Yan HH, Pickup M, Pang Y, Gorska AE, Li Z, Chytil A, Geng Y, Gray JW, Moses HL, Yang L. Gr-1+ CD11b+ myeloid cells tip the balance of immune protection to tumor promotion in the premetastatic lung. Cancer Res. 2010;70(15):6139\u201349. https:\/\/doi.org\/10.1158\/0008-5472.CAN-10-0706.","journal-title":"Cancer Res"},{"issue":"50","key":"1935_CR30","doi-asserted-by":"publisher","first-page":"21248","DOI":"10.1073\/pnas.1015855107","volume":"107","author":"M Kowanetz","year":"2010","unstructured":"Kowanetz M, Wu X, Lee J, Tan M, Hagenbeek T, Qu X, Yu L, Ross J, Korsisaari N, Cao T. Granulocyte-colony stimulating factor promotes lung metastasis through mobilization of Ly6G+ Ly6C+ granulocytes. Proc Natl Acad Sci USA. 2010;107(50):21248\u201355. https:\/\/doi.org\/10.1073\/pnas.1015855107.","journal-title":"Proc Natl Acad Sci USA"},{"issue":"1","key":"1935_CR31","doi-asserted-by":"publisher","first-page":"54","DOI":"10.1158\/2159-8274.CD-10-0028","volume":"1","author":"DG DeNardo","year":"2011","unstructured":"DeNardo DG, Brennan DJ, Rexhepaj E, Ruffell B, Shiao SL, Madden SF, Gallagher WM, Wadhwani N, Keil SD, Junaid SA. Leukocyte complexity predicts breast cancer survival and functionally regulates response to chemotherapy. Cancer Discov. 2011;1(1):54\u201367. https:\/\/doi.org\/10.1158\/2159-8274.CD-10-0028.","journal-title":"Cancer Discov"},{"issue":"3","key":"1935_CR32","doi-asserted-by":"publisher","first-page":"173","DOI":"10.1016\/j.ccr.2009.08.014","volume":"16","author":"A Mantovani","year":"2009","unstructured":"Mantovani A. The yin-yang of tumor-associated neutrophils. Cancer Cell. 2009;16(3):173\u20134. https:\/\/doi.org\/10.1016\/j.ccr.2009.08.014.","journal-title":"Cancer Cell"},{"issue":"3","key":"1935_CR33","doi-asserted-by":"publisher","first-page":"300","DOI":"10.1016\/j.ccr.2011.08.012","volume":"20","author":"Z Granot","year":"2011","unstructured":"Granot Z, Henke E, Comen EA, King TA, Norton L, Benezra R. Tumor entrained neutrophils inhibit seeding in the premetastatic lung. Cancer Cell. 2011;20(3):300\u201314. https:\/\/doi.org\/10.1016\/j.ccr.2011.08.012.","journal-title":"Cancer Cell"},{"issue":"10","key":"1935_CR34","doi-asserted-by":"publisher","first-page":"1264","DOI":"10.1038\/nm.3337","volume":"19","author":"SM Pyonteck","year":"2013","unstructured":"Pyonteck SM, Akkari L, Schuhmacher AJ, Bowman RL, Sevenich L, Quail DF, Olson OC, Quick ML, Huse JT, Teijeiro V. CSF-1R inhibition alters macrophage polarization and blocks glioma progression. Nat Med. 2013;19(10):1264\u201372. https:\/\/doi.org\/10.1038\/nm.3337.","journal-title":"Nat Med"},{"issue":"6","key":"1935_CR35","doi-asserted-by":"publisher","first-page":"777","DOI":"10.1530\/ERC-13-0198","volume":"20","author":"S Aharinejad","year":"2013","unstructured":"Aharinejad S, Salama M, Paulus P, Zins K, Berger A, Singer CF. Elevated CSF1 serum concentration predicts poor overall survival in women with early breast cancer. Endocr Relat Cancer. 2013;20(6):777\u201383. https:\/\/doi.org\/10.1530\/ERC-13-0198.","journal-title":"Endocr Relat Cancer"},{"issue":"1","key":"1935_CR36","doi-asserted-by":"publisher","first-page":"7","DOI":"10.1007\/s00520-017-3854-x","volume":"26","author":"DC Dale","year":"2018","unstructured":"Dale DC, Crawford J, Klippel Z, Reiner M, Osslund T, Fan E, Morrow PK, Allcott K, Lyman GH. A systematic literature review of the efficacy, effectiveness, and safety of filgrastim. Support Care Cancer. 2018;26(1):7\u201320. https:\/\/doi.org\/10.1007\/s00520-017-3854-x.","journal-title":"Support Care Cancer"},{"issue":"13","key":"1935_CR37","doi-asserted-by":"publisher","first-page":"3861","DOI":"10.1182\/bloodadvances.2021005684","volume":"6","author":"DC Dale","year":"2022","unstructured":"Dale DC, Bolyard AA, Shannon JA IV, Connelly JA, Link DC, Bonilla MA, Newburger PE. Outcomes for patients with severe chronic neutropenia treated with granulocyte colony-stimulating factor. Blood Adv. 2022;6(13):3861\u20139. https:\/\/doi.org\/10.1182\/bloodadvances.2021005684.","journal-title":"Blood Adv"},{"issue":"2","key":"1935_CR38","doi-asserted-by":"publisher","first-page":"23","DOI":"10.3978\/j.issn.2305-5839.2014.12.13","volume":"3","author":"BK Aravindan","year":"2015","unstructured":"Aravindan BK, Prabhakar J, Somanathan T, Subhadra L. The role of chemokine receptor 4 and its ligand stromal cell derived factor 1 in breast cancer. Ann Transl Med. 2015;3(2):23. https:\/\/doi.org\/10.3978\/j.issn.2305-5839.2014.12.13.","journal-title":"Ann Transl Med"},{"issue":"2","key":"1935_CR39","doi-asserted-by":"publisher","first-page":"e56951","DOI":"10.1371\/journal.pone.0056951","volume":"8","author":"D Huynh","year":"2013","unstructured":"Huynh D, Ak\u00e7ora D, Malaterre J, Chan CK, Dai X-M, Bertoncello I, Stanley ER, Ramsay RG. CSF-1 receptor-dependent colon development, homeostasis and inflammatory stress response. PloS One. 2013;8(2):e56951. https:\/\/doi.org\/10.1371\/journal.pone.0056951.","journal-title":"PloS One."},{"issue":"10","key":"1935_CR40","doi-asserted-by":"publisher","first-page":"2052","DOI":"10.18632\/aging.101299","volume":"9","author":"D Rajapakse","year":"2017","unstructured":"Rajapakse D, Chen M, Curtis TM, Xu H. PKC\u03b6-dependent upregulation of p27kip1 contributes to oxidative stress induced retinal pigment epithelial cell multinucleation. Aging (Albany NY). 2017;9(10):2052\u201368. https:\/\/doi.org\/10.18632\/aging.101299.","journal-title":"Aging (Albany NY)"},{"issue":"12","key":"1935_CR41","doi-asserted-by":"publisher","first-page":"5019","DOI":"10.1177\/0300060518789038","volume":"46","author":"C Jiang","year":"2018","unstructured":"Jiang C, Gong W, Chen R, Ke H, Qu X, Yang W, Cheng Z. RhoA\/ROCK\/ARHGAP26 signaling in the eutopic and ectopic endometrium is involved in clinical characteristics of adenomyosis. J Int Med Res. 2018;46(12):5019\u201329. https:\/\/doi.org\/10.1177\/0300060518789038.","journal-title":"J Int Med Res"},{"issue":"11","key":"1935_CR42","doi-asserted-by":"publisher","first-page":"5495","DOI":"10.1167\/iovs.08-3193","volume":"50","author":"CS Alge-Priglinger","year":"2009","unstructured":"Alge-Priglinger CS, Kreutzer T, Obholzer K, Wolf A, Mempel M, Kernt M, Kampik A, Priglinger SG. Oxidative stress-mediated induction of MMP-1 and MMP-3 in human RPE cells. Invest Ophthalmol Vis Sci. 2009;50(11):5495\u2013503. https:\/\/doi.org\/10.1167\/iovs.08-3193.","journal-title":"Invest Ophthalmol Vis Sci"},{"issue":"1","key":"1935_CR43","doi-asserted-by":"publisher","first-page":"e54774","DOI":"10.1371\/journal.pone.0054774","volume":"8","author":"Y Jia","year":"2013","unstructured":"Jia Y, Liu D, Xiao D, Ma X, Han S, Zheng Y, Sun S, Zhang M, Gao H, Cui X. Expression of AFP and STAT3 is involved in arsenic trioxide-induced apoptosis and inhibition of proliferation in AFP-producing gastric cancer cells. PLoS One. 2013;8(1):e54774. https:\/\/doi.org\/10.1371\/journal.pone.0054774.","journal-title":"PLoS One"}],"container-title":["Medical Oncology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12032-022-01935-1.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s12032-022-01935-1\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12032-022-01935-1.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,1,28]],"date-time":"2023-01-28T05:57:20Z","timestamp":1674885440000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s12032-022-01935-1"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,1,6]]},"references-count":43,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2023,2]]}},"alternative-id":["1935"],"URL":"https:\/\/doi.org\/10.1007\/s12032-022-01935-1","relation":{},"ISSN":["1559-131X"],"issn-type":[{"value":"1559-131X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,1,6]]},"assertion":[{"value":"17 October 2022","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"7 December 2022","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"6 January 2023","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors whose names are listed immediately below certify that they have NO affiliations with or involvement in any organization or entity with any financial interest (such as honoraria; educational grants; participation in speakers\u2019 bureaus; membership, employment, consultancies, stock ownership, or other equity interest; and expert testimony or patent-licensing arrangements), or non-financial interest (such as personal or professional relationships, affiliations, knowledge or beliefs) in the subject matter or materials discussed in this manuscript.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"All procedures performed in studies involving animals were under the ethical standards of the institutional and national research committee with the 1964 Declaration of Helsinki and its later amendments or comparable ethical standards.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}}],"article-number":"74"}}