{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T23:46:41Z","timestamp":1790812001212,"version":"4.1.0"},"reference-count":42,"publisher":"Springer Science and Business Media LLC","issue":"2","license":[{"start":{"date-parts":[[2025,1,13]],"date-time":"2025-01-13T00:00:00Z","timestamp":1736726400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"},{"start":{"date-parts":[[2025,1,13]],"date-time":"2025-01-13T00:00:00Z","timestamp":1736726400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Med Oncol"],"DOI":"10.1007\/s12032-024-02576-2","type":"journal-article","created":{"date-parts":[[2025,1,13]],"date-time":"2025-01-13T16:16:35Z","timestamp":1736784995000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":14,"title":["Advances in surgical management of chronic lymphedema: current strategies and future directions"],"prefix":"10.1007","volume":"42","author":[{"given":"Sai Anusha","family":"Sanka","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sophia","family":"Chryssofos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rachel A.","family":"Anolik","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Justin M.","family":"Sacks","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2025,1,13]]},"reference":[{"issue":"1","key":"2576_CR1","doi-asserted-by":"publisher","first-page":"12","DOI":"10.1055\/s-0038-1635117","volume":"32","author":"AK Greene","year":"2018","unstructured":"Greene AK, Goss JA. Diagnosis and staging of lymphedema. Semin Plast Surg. 2018;32(1):12\u20136. https:\/\/doi.org\/10.1055\/s-0038-1635117.","journal-title":"Semin Plast Surg"},{"issue":"2","key":"2576_CR2","doi-asserted-by":"publisher","first-page":"51","DOI":"10.5152\/turkjsurg.2017.3870","volume":"33","author":"O Kay\u0131ran","year":"2017","unstructured":"Kay\u0131ran O, Delacruz C, Tane K, Soran A. Lymphedema: from diagnosis to treatment. Turk J Surg. 2017;33(2):51\u20137. https:\/\/doi.org\/10.5152\/turkjsurg.2017.3870.","journal-title":"Turk J Surg."},{"issue":"4","key":"2576_CR3","doi-asserted-by":"publisher","first-page":"288","DOI":"10.1016\/s0002-9343(00)00727-0","volume":"110","author":"SG Rockson","year":"2001","unstructured":"Rockson SG. Lymphedema. Am J Med. 2001;110(4):288\u201395. https:\/\/doi.org\/10.1016\/s0002-9343(00)00727-0.","journal-title":"Am J Med"},{"issue":"2","key":"2576_CR4","doi-asserted-by":"publisher","first-page":"72","DOI":"10.1111\/j.1745-7599.2006.00198.x","volume":"19","author":"DE Gary","year":"2007","unstructured":"Gary DE. Lymphedema diagnosis and management. J Am Acad Nurse Pract. 2007;19(2):72\u20138. https:\/\/doi.org\/10.1111\/j.1745-7599.2006.00198.x.","journal-title":"J Am Acad Nurse Pract"},{"key":"2576_CR5","doi-asserted-by":"publisher","first-page":"147","DOI":"10.1196\/annals.1413.014","volume":"1131","author":"SG Rockson","year":"2008","unstructured":"Rockson SG, Rivera KK. Estimating the population burden of lymphedema. Ann N Y Acad Sci. 2008;1131:147\u201354. https:\/\/doi.org\/10.1196\/annals.1413.014.","journal-title":"Ann N Y Acad Sci"},{"issue":"3","key":"2576_CR6","doi-asserted-by":"publisher","first-page":"1114","DOI":"10.1096\/fj.12-222695","volume":"27","author":"T Avraham","year":"2013","unstructured":"Avraham T, Zampell JC, Yan A, et al. Th2 differentiation is necessary for soft tissue fibrosis and lymphatic dysfunction resulting from lymphedema. FASEB J. 2013;27(3):1114\u201326. https:\/\/doi.org\/10.1096\/fj.12-222695.","journal-title":"FASEB J"},{"key":"2576_CR7","doi-asserted-by":"publisher","first-page":"137","DOI":"10.3389\/fphys.2020.00137","volume":"11","author":"SH Azhar","year":"2020","unstructured":"Azhar SH, Lim HY, Tan BK, Angeli V. The unresolved pathophysiology of lymphedema. Front Physiol. 2020;11:137. https:\/\/doi.org\/10.3389\/fphys.2020.00137.","journal-title":"Front Physiol"},{"issue":"5","key":"2576_CR8","doi-asserted-by":"publisher","first-page":"878","DOI":"10.1016\/j.bbamcr.2011.01.034","volume":"1813","author":"J Scheller","year":"2011","unstructured":"Scheller J, Chalaris A, Schmidt-Arras D, Rose-John S. The pro- and anti-inflammatory properties of the cytokine interleukin-6. Biochim Biophys Acta. 2011;1813(5):878\u201388. https:\/\/doi.org\/10.1016\/j.bbamcr.2011.01.034.","journal-title":"Biochim Biophys Acta"},{"issue":"3","key":"2576_CR9","doi-asserted-by":"publisher","first-page":"246","DOI":"10.1089\/lrb.2017.0003","volume":"15","author":"MT Zaleska","year":"2017","unstructured":"Zaleska MT, Olszewski WL. Serum immune proteins in limb lymphedema reflecting tissue processes caused by lymph stasis and chronic dermato-lymphangio-adenitis (Cellulitis). Lymphat Res Biol. 2017;15(3):246\u201351. https:\/\/doi.org\/10.1089\/lrb.2017.0003.","journal-title":"Lymphat Res Biol"},{"issue":"1","key":"2576_CR10","doi-asserted-by":"publisher","first-page":"3","DOI":"10.1089\/lrb.2008.1022","volume":"7","author":"H Brorson","year":"2009","unstructured":"Brorson H, Ohlin K, Olsson G, Karlsson MK. Breast cancer-related chronic arm lymphedema is associated with excess adipose and muscle tissue. Lymphat Res Biol. 2009;7(1):3\u201310. https:\/\/doi.org\/10.1089\/lrb.2008.1022.","journal-title":"Lymphat Res Biol"},{"key":"2576_CR11","doi-asserted-by":"publisher","first-page":"74","DOI":"10.1002\/micr.21728","volume":"22","author":"C Campisi","year":"2002","unstructured":"Campisi C, Boccardo F. Lymphedema and microsurgery. Microsurgery. 2002;22:74\u201380.","journal-title":"Microsurgery"},{"key":"2576_CR12","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-323-29897-1.00001-2","volume-title":"Principles and practice of lymphedema surgery","author":"MH Cheng","year":"2016","unstructured":"Cheng MH, Chang DW, Patel KM. Principles and practice of lymphedema surgery. Oxford, UK: Elsevier; 2016."},{"issue":"1","key":"2576_CR13","doi-asserted-by":"publisher","first-page":"47","DOI":"10.1111\/j.1742-4801.2005.00066.x","volume":"2","author":"PA Morgan","year":"2005","unstructured":"Morgan PA, Franks PJ, Moffatt CJ. Health-related quality of life with lymphoedema: a review of the literature. Int Wound J. 2005;2(1):47\u201362. https:\/\/doi.org\/10.1111\/j.1742-4801.2005.00066.x.","journal-title":"Int Wound J"},{"key":"2576_CR14","doi-asserted-by":"publisher","unstructured":"Dratnol RA. Function and Quality of Life of Individuals With Lower Extremity Lymphedema: A Scoping Review. Presented at: Rush University; March 31, 2022. https:\/\/doi.org\/10.5014\/ajot.2022.76S1-RP1.","DOI":"10.5014\/ajot.2022.76S1-RP1"},{"key":"2576_CR15","doi-asserted-by":"publisher","first-page":"464","DOI":"10.1097\/01.sap.0000257149.42922.7e","volume":"59","author":"A Warren","year":"2007","unstructured":"Warren A, Brorson H, Borud L, Slavin S. Lymphedema: A Comprehensive Review. Ann Plast Surg. 2007;59:464\u201372. https:\/\/doi.org\/10.1097\/01.sap.0000257149.42922.7e.","journal-title":"Ann Plast Surg"},{"issue":"1","key":"2576_CR16","doi-asserted-by":"publisher","first-page":"20","DOI":"10.1016\/j.soncn.2012.11.004","volume":"29","author":"B Lasinski","year":"2013","unstructured":"Lasinski B. Complete decongestive therapy for treatment of lymphedema. Semin Oncol Nurs. 2013;29(1):20\u20137. https:\/\/doi.org\/10.1016\/j.soncn.2012.11.004.","journal-title":"Semin Oncol Nurs"},{"key":"2576_CR17","doi-asserted-by":"publisher","first-page":"017","DOI":"10.1055\/s-0038-1635119","volume":"32","author":"M Schaverien","year":"2018","unstructured":"Schaverien M, Moeller J, Cleveland S. Nonoperative treatment of lymphedema. Semin Plast Surg. 2018;32:017\u201321. https:\/\/doi.org\/10.1055\/s-0038-1635119.","journal-title":"Semin Plast Surg"},{"issue":"1","key":"2576_CR18","doi-asserted-by":"publisher","first-page":"83","DOI":"10.1186\/s12961-016-0155-7","volume":"14","author":"MM Haby","year":"2016","unstructured":"Haby MM, Chapman E, Clark R, Barreto J, Reveiz L, Lavis JN. What are the best methodologies for rapid reviews of the research evidence for evidence-informed decision making in health policy and practice: a rapid review. Health Res Policy Syst. 2016;14(1):83. https:\/\/doi.org\/10.1186\/s12961-016-0155-7.","journal-title":"Health Res Policy Syst."},{"issue":"1","key":"2576_CR19","doi-asserted-by":"publisher","first-page":"17","DOI":"10.1055\/s-0040-1709372","volume":"53","author":"AJ Forte","year":"2020","unstructured":"Forte AJ, Khan N, Huayllani MT, et al. Lymphaticovenous anastomosis for lower extremity lymphedema: a systematic review. Indian J Plast Surg. 2020;53(1):17\u201324. https:\/\/doi.org\/10.1055\/s-0040-1709372.","journal-title":"Indian J Plast Surg"},{"issue":"5","key":"2576_CR20","doi-asserted-by":"publisher","first-page":"426","DOI":"10.1089\/lrb.2017.0067","volume":"16","author":"AJM Cornelissen","year":"2018","unstructured":"Cornelissen AJM, Beugels J, Ewalds L, et al. Effect of lymphaticovenous anastomosis in breast cancer-related lymphedema: a review of the literature. Lymphat Res Biol. 2018;16(5):426\u201334. https:\/\/doi.org\/10.1089\/lrb.2017.0067.","journal-title":"Lymphat Res Biol"},{"issue":"8","key":"2576_CR21","doi-asserted-by":"publisher","first-page":"e3770","DOI":"10.1097\/GOX.0000000000003770","volume":"9","author":"N Gupta","year":"2021","unstructured":"Gupta N, Verhey EM, Torres-Guzman RA, et al. Outcomes of lymphovenous anastomosis for upper extremity lymphedema: a systematic review. Plast Reconstr Surg Glob Open. 2021;9(8):e3770.","journal-title":"Plast Reconstr Surg Glob Open"},{"issue":"12","key":"2576_CR22","doi-asserted-by":"publisher","first-page":"2624","DOI":"10.1111\/ans.16764","volume":"91","author":"NSJ Tang","year":"2021","unstructured":"Tang NSJ, Ramakrishnan A, Shayan R. Quality-of-life outcomes after operative management of primary and secondary lymphoedema: a systematic review. ANZ J Surg. 2021;91(12):2624\u201336. https:\/\/doi.org\/10.1111\/ans.16764.","journal-title":"ANZ J Surg"},{"issue":"3","key":"2576_CR23","doi-asserted-by":"publisher","first-page":"565","DOI":"10.3390\/cancers12030565","volume":"12","author":"M Coriddi","year":"2020","unstructured":"Coriddi M, Dayan J, Sobti N, et al. Systematic review of patient-reported outcomes following surgical treatment of lymphedema. Cancers (Basel). 2020;12(3):565. https:\/\/doi.org\/10.3390\/cancers12030565.","journal-title":"Cancers (Basel)."},{"key":"2576_CR24","doi-asserted-by":"publisher","DOI":"10.7759\/cureus.5913","author":"AJ Forte","year":"2019","unstructured":"Forte AJ, Huayllani MT, Boczar D, Ciudad P, McLaughlin SA. Lipoaspiration for the treatment of lower limb lymphedema: a comprehensive systematic review. Cureus. 2019. https:\/\/doi.org\/10.7759\/cureus.5913.","journal-title":"Cureus."},{"issue":"2","key":"2576_CR25","doi-asserted-by":"publisher","first-page":"195","DOI":"10.1097\/SAP.0000000000002862","volume":"88","author":"F Fallahian","year":"2022","unstructured":"Fallahian F, Tadisina KK, Xu KY. Efficacy of microsurgical treatment of primary lymphedema: a systematic review. Ann Plast Surg. 2022;88(2):195\u20139. https:\/\/doi.org\/10.1097\/SAP.0000000000002862.","journal-title":"Ann Plast Surg"},{"issue":"9","key":"2576_CR26","doi-asserted-by":"publisher","first-page":"1234","DOI":"10.1016\/j.bjps.2016.06.022","volume":"69","author":"CN Ozturk","year":"2016","unstructured":"Ozturk CN, Ozturk C, Glasgow M, et al. Free vascularized lymph node transfer for treatment of lymphedema: a systematic evidence based review. J Plast Reconstr Aesthet Surg. 2016;69(9):1234\u201347. https:\/\/doi.org\/10.1016\/j.bjps.2016.06.022.","journal-title":"J Plast Reconstr Aesthet Surg"},{"key":"2576_CR27","doi-asserted-by":"publisher","DOI":"10.1097\/GOX.0000000000004529","author":"EM Verhey","year":"2022","unstructured":"Verhey EM, Kandi LA, Lee YS, et al. Outcomes of lymphovenous anastomosis for lower extremity lymphedema: a systematic review. Plast Reconstr Surg Glob Open. 2022. https:\/\/doi.org\/10.1097\/GOX.0000000000004529.","journal-title":"Plast Reconstr Surg Glob Open"},{"issue":"2","key":"2576_CR28","doi-asserted-by":"publisher","first-page":"212","DOI":"10.1055\/a-2253-9859","volume":"51","author":"MA Gaxiola-Garc\u00eda","year":"2024","unstructured":"Gaxiola-Garc\u00eda MA, Escand\u00f3n JM, Manrique OJ, et al. Surgical treatment for primary lymphedema: a systematic review of the literature. Arch Plast Surg. 2024;51(2):212\u201333. https:\/\/doi.org\/10.1055\/a-2253-9859.","journal-title":"Arch Plast Surg"},{"issue":"3","key":"2576_CR29","doi-asserted-by":"publisher","first-page":"811","DOI":"10.1016\/j.jvsv.2020.11.022","volume":"9","author":"L Gr\u00fcnherz","year":"2021","unstructured":"Gr\u00fcnherz L, Hulla H, Uyulmaz S, et al. Patient-reported outcomes following lymph reconstructive surgery in lower limb lymphedema: a systematic review of literature. J Vasc Surg Venous Lymphat Disord. 2021;9(3):811-819.e2.","journal-title":"J Vasc Surg Venous Lymphat Disord"},{"issue":"5","key":"2576_CR30","doi-asserted-by":"publisher","first-page":"1002","DOI":"10.1007\/s12282-021-01274-5","volume":"28","author":"K Gasteratos","year":"2021","unstructured":"Gasteratos K, Morsi-Yeroyannis A, Vlachopoulos NC, et al. Microsurgical techniques in the treatment of breast cancer-related lymphedema: a systematic review of efficacy and patient outcomes. Breast Cancer. 2021;28(5):1002\u201315.","journal-title":"Breast Cancer"},{"key":"2576_CR31","doi-asserted-by":"publisher","first-page":"232","DOI":"10.1089\/lrb.2024.0014","volume":"22","author":"A Zapata-Ospina","year":"2024","unstructured":"Zapata-Ospina A, Lopera-Mu\u00f1et\u00f3n C, Betancur-Bedoya SP, et al. Effectiveness of lymphovenular anastomosis and complex decongestive therapy for the treatment of lymphedema in patients with breast cancer: a systematic review. Lymphat Res Biol. 2024;22:232\u201340.","journal-title":"Lymphat Res Biol"},{"issue":"1","key":"2576_CR32","doi-asserted-by":"publisher","first-page":"2238","DOI":"10.1038\/s41598-024-52489-3","volume":"14","author":"YMJ Jonis","year":"2024","unstructured":"Jonis YMJ, Wolfs JAGN, Hummelink S, et al. The 6 month interim analysis of a randomized controlled trial assessing the quality of life in patients with breast cancer related lymphedema undergoing lymphaticovenous anastomosis vs. conservative therapy. Sci Rep. 2024;14(1):2238.","journal-title":"Sci Rep"},{"issue":"1","key":"2576_CR33","doi-asserted-by":"publisher","first-page":"22","DOI":"10.1186\/s40463-018-0263-1","volume":"47","author":"U Alamoudi","year":"2018","unstructured":"Alamoudi U, Taylor B, MacKay C, et al. Submental liposuction for the management of lymphedema following head and neck cancer treatment: a randomized controlled trial. J Otolaryngol Head Neck Surg. 2018;47(1):22.","journal-title":"J Otolaryngol Head Neck Surg"},{"issue":"1","key":"2576_CR34","doi-asserted-by":"publisher","first-page":"73","DOI":"10.1007\/s10549-016-3716-0","volume":"156","author":"D Dionyssiou","year":"2016","unstructured":"Dionyssiou D, Demiri E, Tsimponis A, et al. A randomized control study of treating secondary stage II breast cancer-related lymphoedema with free lymph node transfer. Breast Cancer Res Treat. 2016;156(1):73\u20139.","journal-title":"Breast Cancer Res Treat"},{"issue":"3","key":"2576_CR35","doi-asserted-by":"publisher","first-page":"786","DOI":"10.1016\/j.jvsv.2021.08.023","volume":"10","author":"H Winters","year":"2022","unstructured":"Winters H, Tielemans HJP, Paulus V, et al. A systematic review and meta-analysis of vascularized lymph node transfer for breast cancer-related lymphedema. J Vasc Surg Venous Lymphat Disord. 2022;10(3):786-795.e1. https:\/\/doi.org\/10.1016\/j.jvsv.2021.08.023.","journal-title":"J Vasc Surg Venous Lymphat Disord"},{"key":"2576_CR36","doi-asserted-by":"publisher","first-page":"233","DOI":"10.1016\/j.ejca.2021.02.043","volume":"151","author":"J Ward","year":"2021","unstructured":"Ward J, King I, Monroy-Iglesias M, et al. A meta-analysis of the efficacy of vascularised lymph node transfer in reducing limb volume and cellulitis episodes in patients with cancer treatment-related lymphoedema. Eur J Cancer. 2021;151:233\u201344. https:\/\/doi.org\/10.1016\/j.ejca.2021.02.043.","journal-title":"Eur J Cancer"},{"issue":"2","key":"2576_CR37","doi-asserted-by":"publisher","first-page":"503","DOI":"10.21037\/gs.2020.03.14","volume":"9","author":"KE Park","year":"2020","unstructured":"Park KE, Allam O, Chandler L, et al. Surgical management of lymphedema: a review of current literature. Gland Surg. 2020;9(2):503\u201311. https:\/\/doi.org\/10.21037\/gs.2020.03.14.","journal-title":"Gland Surg"},{"key":"2576_CR38","doi-asserted-by":"publisher","first-page":"266","DOI":"10.1007\/s12032-024-02449-8","volume":"41","author":"J Sacks","year":"2024","unstructured":"Sacks J, Riley B, Doubblestein D, et al. Expert-consensus on lymphedema surgeries: candidacy, prehabilitation, and postoperative care. Med Oncol. 2024;41:266. https:\/\/doi.org\/10.1007\/s12032-024-02449-8.","journal-title":"Med Oncol"},{"key":"2576_CR39","doi-asserted-by":"publisher","first-page":"47","DOI":"10.1007\/978-3-030-93039-4_7","volume-title":"Multimodal Management of Upper and Lower Extremity Lymphedema","author":"MV Schaverien","year":"2022","unstructured":"Schaverien MV, Dayan JH. Key topic: Patient selection and evidence-based algorithmic approach to surgical management of lymphedema. In: Schaverien MV, Dayan JH, editors. Multimodal Management of Upper and Lower Extremity Lymphedema. New York: Springer International Publishing; 2022. p. 47\u201352. https:\/\/doi.org\/10.1007\/978-3-030-93039-4_7."},{"issue":"2","key":"2576_CR40","first-page":"143","volume":"117","author":"AM Kareh","year":"2020","unstructured":"Kareh AM, Xu KY. Surgical management of lymphedema. Mo Med. 2020;117(2):143\u20138.","journal-title":"Mo Med"},{"key":"2576_CR41","doi-asserted-by":"publisher","first-page":"1189","DOI":"10.1245\/s10434-014-3515-y","volume":"21","author":"JW Granzow","year":"2014","unstructured":"Granzow JW, Soderberg JM, Kaji AH, et al. An effective system of surgical treatment of lymphedema. Ann Surg Oncol. 2014;21:1189\u201394. https:\/\/doi.org\/10.1245\/s10434-014-3515-y.","journal-title":"Ann Surg Oncol"},{"issue":"2","key":"2576_CR42","doi-asserted-by":"publisher","first-page":"178","DOI":"10.1016\/j.bjps.2016.11.016","volume":"70","author":"H Winters","year":"2017","unstructured":"Winters H, Tielemans HJ, Sprangers PN, Ulrich DJ. Peri-operative care for patients undergoing lymphaticovenular anastomosis: a systematic review. J Plast Reconstr Aesthet Surg. 2017;70(2):178\u201388. https:\/\/doi.org\/10.1016\/j.bjps.2016.11.016.","journal-title":"J Plast Reconstr Aesthet Surg"}],"container-title":["Medical Oncology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12032-024-02576-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s12032-024-02576-2\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12032-024-02576-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,1,29]],"date-time":"2025-01-29T22:35:16Z","timestamp":1738190116000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s12032-024-02576-2"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,1,13]]},"references-count":42,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2025,2]]}},"alternative-id":["2576"],"URL":"https:\/\/doi.org\/10.1007\/s12032-024-02576-2","relation":{},"ISSN":["1559-131X"],"issn-type":[{"value":"1559-131X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,1,13]]},"assertion":[{"value":"9 August 2024","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"26 November 2024","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"13 January 2025","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare no competing interests.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interests"}}],"article-number":"44"}}