{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,9]],"date-time":"2026-09-09T04:06:27Z","timestamp":1788926787681,"version":"build-2803163510"},"reference-count":52,"publisher":"Springer Science and Business Media LLC","issue":"9","license":[{"start":{"date-parts":[[2026,7,17]],"date-time":"2026-07-17T00:00:00Z","timestamp":1784246400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2026,7,17]],"date-time":"2026-07-17T00:00:00Z","timestamp":1784246400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"funder":[{"name":"Deanship of Scientific Research at Imam Mohammad Ibn Saud Islamic University","award":["000"],"award-info":[{"award-number":["000"]}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Med Oncol"],"DOI":"10.1007\/s12032-026-03335-1","type":"journal-article","created":{"date-parts":[[2026,7,17]],"date-time":"2026-07-17T04:40:07Z","timestamp":1784263207000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Formulation development and preliminary biological evaluation of a menthol modified thermoresponsive tamoxifen sol-gel"],"prefix":"10.1007","volume":"43","author":[{"given":"Saleha","family":"Faheem","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huma","family":"Hameed","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sami A.","family":"Al-Hussain","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ali","family":"Irfan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shazia Akram","family":"Ghumman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5643-9202","authenticated-orcid":false,"given":"Magdi E. A.","family":"Zaki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,7,17]]},"reference":[{"key":"3335_CR1","doi-asserted-by":"publisher","first-page":"1154","DOI":"10.1038\/s41591-025-03502-3","volume":"31","author":"J Kim","year":"2025","unstructured":"Kim J, et al. Global patterns and trends in breast cancer incidence and mortality across 185 countries. Nat Med. 2025;31:1154\u201362. https:\/\/doi.org\/10.1038\/s41591-025-03502-3.","journal-title":"Nat Med"},{"key":"3335_CR2","volume-title":"Seminars in Oncology Nursing","author":"A Shewbridge","year":"2024","unstructured":"Shewbridge A, Meade E, Dowling M. Seminars in Oncology Nursing. Elsevier; 2024."},{"key":"3335_CR3","doi-asserted-by":"publisher","DOI":"10.3390\/cancers15061917","volume":"15","author":"JW Zhu","year":"2023","unstructured":"Zhu JW, Charkhchi P, Adekunte S, Akbari MR. What is known about breast cancer in young women? Cancers (Basel). 2023;15:1917.","journal-title":"Cancers (Basel)"},{"key":"3335_CR4","doi-asserted-by":"publisher","first-page":"945","DOI":"10.1007\/s13346-023-01443-3","volume":"14","author":"M Nasr","year":"2024","unstructured":"Nasr M, Hashem F, Teiama M, Tantawy N, Abdelmoniem R. Folic acid grafted mixed polymeric micelles as a targeted delivery strategy for tamoxifen citrate in treatment of breast cancer. Drug Deliv Transl Res. 2024;14:945\u201358.","journal-title":"Drug Deliv Transl Res"},{"key":"3335_CR5","doi-asserted-by":"publisher","first-page":"259","DOI":"10.1002\/jps.2600760317","volume":"76","author":"I Goldberg","year":"1987","unstructured":"Goldberg I, Becker Y. Polymorphs of tamoxifen citrate: detailed structural characterization of the stable form. J Pharm Sci. 1987;76:259\u201364. https:\/\/doi.org\/10.1002\/jps.2600760317.","journal-title":"J Pharm Sci"},{"key":"3335_CR6","doi-asserted-by":"publisher","DOI":"10.1016\/j.prp.2025.156308","volume":"277","author":"K Mangu","year":"2026","unstructured":"Mangu K, Gandhi AN, Rizwanullah M. Progress in nanotechnology-based strategies to enhance tamoxifen therapy for breast cancer management. Pathol Res Pract. 2026;277:156308. https:\/\/doi.org\/10.1016\/j.prp.2025.156308.","journal-title":"Pathol Res Pract"},{"key":"3335_CR7","doi-asserted-by":"publisher","DOI":"10.1007\/s12672-025-03635-4","volume":"16","author":"R Jahangiri","year":"2025","unstructured":"Jahangiri R. Genetic and epigenetic contribution to tamoxifen resistance in breast cancer, concepts to drive therapeutic strategies. Discov Oncol. 2025;16:1790. https:\/\/doi.org\/10.1007\/s12672-025-03635-4.","journal-title":"Discov Oncol"},{"key":"3335_CR8","doi-asserted-by":"publisher","DOI":"10.1007\/s44442-026-00071-z","author":"H Fiaz","year":"2026","unstructured":"Fiaz H, et al. A novel in situ gel system for potentiating doxorubicin efficacy through reserpine co-therapy. J Saudi Chem Soc. 2026. https:\/\/doi.org\/10.1007\/s44442-026-00071-z.","journal-title":"J Saudi Chem Soc"},{"key":"3335_CR9","doi-asserted-by":"publisher","first-page":"746","DOI":"10.1016\/j.ijbiomac.2022.11.285","volume":"226","author":"G Jeswani","year":"2023","unstructured":"Jeswani G, et al. Exploration of hemocompatibility and intratumoral accumulation of paclitaxel after loco-regional administration of thermoresponsive hydrogel composed of poloxamer and xanthan gum: an application to dose-dense chemotherapy. Int J Biol Macromol. 2023;226:746\u201359.","journal-title":"Int J Biol Macromol"},{"key":"3335_CR10","first-page":"614","volume":"23","author":"H Singh","year":"2023","unstructured":"Singh H, et al. Camphor and menthol as anticancer agents: Synthesis structure-activity relationship and interaction with cancer cell lines. Anti-Cancer Agents Med Chem (Form Curr Med Chem-Anti-Cancer Agents). 2023;23:614\u201323.","journal-title":"Anti-Cancer Agents Med Chem (Form Curr Med Chem-Anti-Cancer Agents)"},{"key":"3335_CR11","doi-asserted-by":"publisher","first-page":"1553","DOI":"10.1080\/10408398.2023.2296991","volume":"65","author":"A Kazemi","year":"2025","unstructured":"Kazemi A, Iraji A, Esmaealzadeh N, Salehi M, Hashempur MH. Peppermint and menthol: a review on their biochemistry, pharmacological activities, clinical applications, and safety considerations. Crit Rev Food Sci Nutr. 2025;65:1553\u201378.","journal-title":"Crit Rev Food Sci Nutr"},{"key":"3335_CR12","doi-asserted-by":"publisher","first-page":"17","DOI":"10.1007\/s00894-021-05010-w","volume":"28","author":"HO Rasul","year":"2022","unstructured":"Rasul HO, Aziz BK, Ghafour DD, Kivrak A. In silico molecular docking and dynamic simulation of eugenol compounds against breast cancer. J Mol Model. 2022;28:17.","journal-title":"J Mol Model"},{"key":"3335_CR13","doi-asserted-by":"publisher","first-page":"4349","DOI":"10.31557\/apjcp.2025.26.12.4349","volume":"26","author":"S Turini","year":"2025","unstructured":"Turini S, et al. Comparative molecular docking analysis, of natural and synthetic ligands, targeting BRCA1, BRCA2, ER, and PR in breast cancer treatment. Asian Pac J Cancer Prev. 2025;26:4349\u201361. https:\/\/doi.org\/10.31557\/apjcp.2025.26.12.4349.","journal-title":"Asian Pac J Cancer Prev"},{"key":"3335_CR14","doi-asserted-by":"publisher","first-page":"817","DOI":"10.3390\/gels9100817","volume":"9","author":"M Riaz","year":"2023","unstructured":"Riaz M, et al. Lamotrigine-Loaded Poloxamer-Based Thermo-Responsive Sol\u2013Gel: Formulation, In vitro Assessment, Ex Vivo Permeation, and Toxicology Study. Gels. 2023;9:817.","journal-title":"Gels"},{"key":"3335_CR15","doi-asserted-by":"publisher","first-page":"2954","DOI":"10.3390\/polym16212954","volume":"16","author":"R Alsheikh","year":"2024","unstructured":"Alsheikh R, et al. Formulation of thermo-sensitive in situ gels loaded with dual spectrum antibiotics of azithromycin and ofloxacin. Polymers. 2024;16:2954.","journal-title":"Polymers"},{"key":"3335_CR16","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1007\/s12032-024-02466-7","volume":"41","author":"W Ashfaq","year":"2024","unstructured":"Ashfaq W, Rehman K, Shahid A, Younis MN. Therapeutic response and safety of radioligand therapy with 177Lu-PSMA-617 in metastatic castration-resistant prostate cancer patients. Med Oncol. 2024;41:1\u201310.","journal-title":"Med Oncol"},{"key":"3335_CR17","doi-asserted-by":"publisher","first-page":"830","DOI":"10.3390\/gels9100830","volume":"9","author":"M Bajwa","year":"2023","unstructured":"Bajwa M, et al. Thermo-Responsive Sol-Gel-Based Nano-Carriers Containing Terbinafine HCl: Formulation, In vitro and Ex Vivo Characterization, and Antifungal Activity. Gels. 2023;9:830.","journal-title":"Gels"},{"key":"3335_CR18","doi-asserted-by":"publisher","DOI":"10.1016\/j.petrol.2021.108659","volume":"203","author":"OE Agwu","year":"2021","unstructured":"Agwu OE, et al. A critical review of drilling mud rheological models. J Petrol Sci Eng. 2021;203:108659.","journal-title":"J Petrol Sci Eng"},{"key":"3335_CR19","doi-asserted-by":"publisher","DOI":"10.3390\/gels8070456","volume":"8","author":"MH Alyami","year":"2022","unstructured":"Alyami MH, et al. Tamoxifen citrate containing topical nanoemulgel prepared by ultrasonication technique: formulation design and in vitro evaluation. Gels. 2022;8:456.","journal-title":"Gels"},{"key":"3335_CR20","doi-asserted-by":"publisher","first-page":"563","DOI":"10.1007\/s10812-020-01039-6","volume":"87","author":"H Kushwah","year":"2020","unstructured":"Kushwah H, Hans T, Chauhan M, Mittal G, Sandal N. Development and validation of the spectrophotometric method for the determination of menthol. J Appl Spectrosc. 2020;87:563\u20137. https:\/\/doi.org\/10.1007\/s10812-020-01039-6.","journal-title":"J Appl Spectrosc"},{"key":"3335_CR21","doi-asserted-by":"publisher","first-page":"95","DOI":"10.4155\/tde-2021-0069","volume":"13","author":"S Salatin","year":"2022","unstructured":"Salatin S, Tarzamani M, Farjami A, Jelvehgari M. Development and characterization of a novel mucoadhesive sol-gel suppository of sumatriptan: design, optimization, in vitro and ex vivo evaluation for rectal drug delivery. Ther Deliv. 2022;13:95\u2013108.","journal-title":"Ther Deliv"},{"key":"3335_CR22","doi-asserted-by":"publisher","DOI":"10.3390\/app122312019","volume":"12","author":"H Fatahi","year":"2022","unstructured":"Fatahi H, Claverie J, Poncet S. Thermal characterization of phase change materials by differential scanning calorimetry: a review. Appl Sci. 2022;12:12019.","journal-title":"Appl Sci"},{"key":"3335_CR23","doi-asserted-by":"publisher","first-page":"5006","DOI":"10.1021\/acs.cgd.6b00575","volume":"16","author":"DA Ziolkowska","year":"2016","unstructured":"Ziolkowska DA, et al. In situ XRD and TEM studies of sol-gel-based synthesis of LiFePO4. Cryst Growth Des. 2016;16:5006\u201313.","journal-title":"Cryst Growth Des"},{"key":"3335_CR24","doi-asserted-by":"publisher","DOI":"10.1007\/s43939-022-00022-6","volume":"2","author":"M Patel","year":"2022","unstructured":"Patel M, Mishra S, Verma R, Shikha D. Synthesis of ZnO and CuO nanoparticles via sol gel method and its characterization by using various technique. Discov Mater. 2022;2:1.","journal-title":"Discov Mater"},{"key":"3335_CR25","doi-asserted-by":"publisher","DOI":"10.1016\/j.jddst.2023.104962","volume":"89","author":"C Huang","year":"2023","unstructured":"Huang C, et al. Preparation and characteristics of a thermosensitive in situ gel loaded with chitosan nanoparticles for optimal ocular delivery of chloramphenicol. J Drug Deliv Sci Technol. 2023;89:104962.","journal-title":"J Drug Deliv Sci Technol"},{"key":"3335_CR26","first-page":"617","volume":"15","author":"H Elmotasem","year":"2020","unstructured":"Elmotasem H, Awad GEJA. A stepwise optimization strategy to formulate in situ gelling formulations comprising fluconazole-hydroxypropyl-beta-cyclodextrin complex loaded niosomal vesicles and Eudragit nanoparticles for enhanced antifungal activity and prolonged ocular delivery. Asia J Pharm Sci. 2020;15:617\u201336.","journal-title":"Asia J Pharm Sci"},{"key":"3335_CR27","doi-asserted-by":"publisher","first-page":"522","DOI":"10.1080\/17458080.2022.2112919","volume":"17","author":"MK Waqas","year":"2022","unstructured":"Waqas MK, et al. Alginate-coated chitosan nanoparticles for pH-dependent release of tamoxifen citrate. J Exp Nanosci. 2022;17:522\u201334.","journal-title":"J Exp Nanosci"},{"key":"3335_CR28","doi-asserted-by":"publisher","first-page":"38806","DOI":"10.1021\/acsomega.3c01153","volume":"8","author":"MA Mir","year":"2023","unstructured":"Mir MA, et al. Design-of-experiment-assisted fabrication of biodegradable polymeric nanoparticles: in vitro characterization, biological activity, and in vivo assessment. ACS Omega. 2023;8:38806\u201321.","journal-title":"ACS Omega"},{"key":"3335_CR29","doi-asserted-by":"publisher","DOI":"10.3390\/polym14030427","volume":"14","author":"KR Vijaya Rani","year":"2022","unstructured":"Vijaya Rani KR, et al. The effect of polymers on drug release kinetics in nanoemulsion in situ gel formulation. Polymers (Basel). 2022;14:427.","journal-title":"Polymers (Basel)"},{"key":"3335_CR30","doi-asserted-by":"publisher","first-page":"26","DOI":"10.1002\/jbm.b.31370","volume":"91","author":"CY Gong","year":"2009","unstructured":"Gong CY, et al. Acute toxicity evaluation of biodegradable in situ gel-forming controlled drug delivery system based on thermosensitive PEG-PCL-PEG hydrogel. J Biomed Mater Res B Appl Biomater. 2009;91:26\u201336.","journal-title":"J Biomed Mater Res B Appl Biomater"},{"key":"3335_CR31","doi-asserted-by":"publisher","DOI":"10.3390\/ijms23052725","volume":"23","author":"S Noreen","year":"2022","unstructured":"Noreen S, et al. pH responsive Abelmoschus esculentus mucilage and administration of methotrexate: in-vitro antitumor and in-vivo toxicity evaluation. Int J Mol Sci. 2022;23:2725.","journal-title":"Int J Mol Sci"},{"key":"3335_CR32","doi-asserted-by":"publisher","DOI":"10.1016\/j.arabjc.2022.104463","volume":"16","author":"SA Ghumman","year":"2023","unstructured":"Ghumman SA, et al. Chitosan-Linseed mucilage polyelectrolyte complex nanoparticles of methotrexate: In vitro cytotoxic efficacy and toxicological studies. Arab J Chem. 2023;16:104463.","journal-title":"Arab J Chem"},{"key":"3335_CR33","doi-asserted-by":"publisher","first-page":"394","DOI":"10.29271\/jcpsp.2024.04.394","volume":"34","author":"W Ashfaq","year":"2024","unstructured":"Ashfaq W, Rehman K, Shahid A, Younis MN. SUV max as predictor of metastatic disease on 18 F-FDG PET-CT in hepatocellular carcinoma. J Coll Physicians Surg Pak:JCPSP. 2024;34:394\u20139.","journal-title":"J Coll Physicians Surg Pak:JCPSP"},{"key":"3335_CR34","doi-asserted-by":"publisher","DOI":"10.1016\/j.cscee.2023.100405","volume":"8","author":"R Alabada","year":"2023","unstructured":"Alabada R, et al. Investigation of effective parameters in the production of alumina gel through the sol-gel method. Case Stud Chem Environ Eng. 2023;8:100405.","journal-title":"Case Stud Chem Environ Eng"},{"key":"3335_CR35","doi-asserted-by":"publisher","first-page":"1297","DOI":"10.1007\/s11094-022-02789-7","volume":"56","author":"MA Khattak","year":"2022","unstructured":"Khattak MA, et al. Using the Design of experiments for development, validation, and optimization of HPLC-UV assay of tamoxifen citrate in polymeric nanoparticles. Pharm Chem J. 2022;56:1297\u2013306.","journal-title":"Pharm Chem J"},{"key":"3335_CR36","doi-asserted-by":"publisher","first-page":"1","DOI":"10.2478\/pjct-2022-0008","volume":"24","author":"G Zhu","year":"2022","unstructured":"Zhu G, et al. (-)-Menthol-\u03b2-cyclodextrin inclusion complex production and characterization. Pol J Chem Technol. 2022;24:1\u20137.","journal-title":"Pol J Chem Technol"},{"key":"3335_CR37","doi-asserted-by":"publisher","DOI":"10.1016\/j.jddst.2023.105175","volume":"91","author":"M Khan","year":"2024","unstructured":"Khan M, et al. Formulation of chitosan based lipid polymer hybrid nanocarrier system for oral delivery of tamoxifen citrate: toxicological and hemocompatibility evaluation. J Drug Deliv Sci Technol. 2024;91:105175.","journal-title":"J Drug Deliv Sci Technol"},{"key":"3335_CR38","doi-asserted-by":"publisher","first-page":"3973","DOI":"10.1021\/acs.cgd.2c00362","volume":"22","author":"A Alhadid","year":"2022","unstructured":"Alhadid A, Jandl C, Mokrushina L, Minceva M. Cocrystal formation in l-menthol\/phenol eutectic system: experimental study and thermodynamic modeling. Cryst Growth Des. 2022;22:3973\u201380.","journal-title":"Cryst Growth Des"},{"key":"3335_CR39","doi-asserted-by":"publisher","first-page":"536","DOI":"10.1007\/s12613-021-2251-0","volume":"29","author":"YJ Tarzanagh","year":"2022","unstructured":"Tarzanagh YJ, Seifzadeh D, Samadianfard R. Combining the 8-hydroxyquinoline intercalated layered double hydroxide film and sol-gel coating for active corrosion protection of the magnesium alloy. Int J Miner Metall Mater. 2022;29:536\u201346.","journal-title":"Int J Miner Metall Mater"},{"key":"3335_CR40","doi-asserted-by":"publisher","DOI":"10.1080\/10717544.2023.2219420","volume":"30","author":"M Mashal","year":"2023","unstructured":"Mashal M, et al. Stability of polymeric cationic niosomes and their plasmid DNA-based complexes as gene delivery carriers. Drug Deliv. 2023;30:2219420.","journal-title":"Drug Deliv"},{"key":"3335_CR41","doi-asserted-by":"publisher","DOI":"10.1016\/j.psj.2023.103245","volume":"103","author":"A Lakyat","year":"2024","unstructured":"Lakyat A, et al. Nanoemulsion-based plant essential oil formulations: in vitro evaluation of pesticidal activity against ectoparasites in poultry. Poult Sci. 2024;103:103245.","journal-title":"Poult Sci"},{"key":"3335_CR42","doi-asserted-by":"publisher","DOI":"10.3390\/pharmaceutics15051364","volume":"15","author":"IS Bayer","year":"2023","unstructured":"Bayer IS. Controlled drug release from nanoengineered polysaccharides. Pharmaceutics. 2023;15:1364.","journal-title":"Pharmaceutics"},{"key":"3335_CR43","doi-asserted-by":"crossref","unstructured":"Divsalar B, Heydari P, Habibollah G, Tamaddon G. Hematological parameters changes in patients with breast cancer. Clin Lab. 2021.","DOI":"10.7754\/Clin.Lab.2020.201103"},{"key":"3335_CR44","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1208\/s12249-024-02786-x","volume":"25","author":"H Hameed","year":"2024","unstructured":"Hameed H, Faheem S, Paiva-Santos AC, Sarwar HS, Jamshaid M. A comprehensive review of hydrogel-based drug delivery systems: classification, properties, recent trends, and applications. AAPS Pharm Sci Tech. 2024;25:1\u201327.","journal-title":"AAPS Pharm Sci Tech"},{"key":"3335_CR45","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejps.2023.106638","volume":"192","author":"JS Passos","year":"2024","unstructured":"Passos JS, Apolinario AC, Ishida K, Martins TS, Lopes LB. Nanostructured lipid carriers loaded into in situ gels for breast cancer local treatment. Eur J Pharm Sci. 2024;192:106638.","journal-title":"Eur J Pharm Sci"},{"key":"3335_CR46","doi-asserted-by":"publisher","DOI":"10.1016\/j.jciso.2024.100120","volume":"15","author":"LS Viswanadha","year":"2024","unstructured":"Viswanadha LS, Arcot Y, Lin Y-T, Akbulut MEJJO. A comparative investigation of release kinetics of paclitaxel from natural protein and macromolecular nanocarriers in nanoscale drug delivery systems. JCIS Open. 2024;15:100120.","journal-title":"JCIS Open"},{"key":"3335_CR47","doi-asserted-by":"publisher","first-page":"114192","DOI":"10.1016\/j.mtcomm.2025.114192","volume":"49","author":"S Ahmadi","year":"2025","unstructured":"Ahmadi S, Olad A, Fathi M. In situ fast gelling poloxamer 407\/ poly(NIPAAm-co-MA) thermosensitive\u00a00 0injectable hydrogels incorporating chitosan\/ curcumin nanoparticles for dual drug delivery. Mater Today Commun. 2025;49:114192. https:\/\/doi.org\/10.1016\/j.mtcomm.2025.114192.","journal-title":"Mater Today Commun"},{"key":"3335_CR48","doi-asserted-by":"publisher","DOI":"10.1038\/s44386-026-00039-4","volume":"3","author":"M Mirgaux","year":"2026","unstructured":"Mirgaux M, Barcelli V, Chua ACY, Bifani P, Wintjens R. AI-guided competitive docking for virtual screening and compound efficacy prediction. NPJ Drug Discov. 2026;3:6. https:\/\/doi.org\/10.1038\/s44386-026-00039-4.","journal-title":"NPJ Drug Discov"},{"key":"3335_CR49","doi-asserted-by":"publisher","first-page":"1899","DOI":"10.3390\/biomedicines13081899","volume":"13","author":"T Zeng","year":"2025","unstructured":"Zeng T, et al. Research strategies and methods of hydrogels for antitumor drug delivery. Biomedicines. 2025;13:1899.","journal-title":"Biomedicines"},{"key":"3335_CR50","doi-asserted-by":"publisher","DOI":"10.1016\/j.crtox.2025.100271","volume":"10","author":"K Takahashi","year":"2026","unstructured":"Takahashi K, Ohta T. Ca(2+)-independent cytotoxicity of menthol in the A549 lung cancer cell line. Curr Res Toxicol. 2026;10:100271. https:\/\/doi.org\/10.1016\/j.crtox.2025.100271.","journal-title":"Curr Res Toxicol"},{"key":"3335_CR51","volume-title":"Natural Products: Phytochemistry, Botany, Metabolism of Alkaloids, Phenolics and Terpenes","author":"DF Silva","year":"2025","unstructured":"Silva DF, et al. In: KishanGopal R, Jean-Michel M, editors., et al., Natural Products: Phytochemistry, Botany, Metabolism of Alkaloids, Phenolics and Terpenes. Berlin Heidelberg: Springer; 2025."},{"key":"3335_CR52","doi-asserted-by":"publisher","DOI":"10.1186\/s12885-025-13693-0","volume":"25","author":"X Wu","year":"2025","unstructured":"Wu X, et al. Intraductal chemotherapy for triple-negative breast cancer: a pathway to minimally invasive clinical treatment. BMC Cancer. 2025;25:285. https:\/\/doi.org\/10.1186\/s12885-025-13693-0.","journal-title":"BMC Cancer"}],"container-title":["Medical Oncology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12032-026-03335-1.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s12032-026-03335-1","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12032-026-03335-1.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,9]],"date-time":"2026-09-09T03:20:15Z","timestamp":1788924015000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s12032-026-03335-1"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,7,17]]},"references-count":52,"journal-issue":{"issue":"9","published-online":{"date-parts":[[2026,9]]}},"alternative-id":["3335"],"URL":"https:\/\/doi.org\/10.1007\/s12032-026-03335-1","relation":{},"ISSN":["1559-131X"],"issn-type":[{"value":"1559-131X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,7,17]]},"assertion":[{"value":"6 March 2026","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"26 June 2026","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"17 July 2026","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"The authors declare no competing interests.","order":1,"name":"Ethics","label":"Competing interests","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Animals involved experimental protocols were approved by the Research Ethics Committee of the University of Central Punjab (UCP, Lahore; Ref. No. UCP\/ORIC\/TDF\/App#08\/2024)\u200b. All the experimental protocols and test methodologies were conducted in accordance with the Research Ethics Committee of the University of Central Punjab. It is also certified that all procedures adhered to the OECD acute toxicity guidelines with arrive reporting standards (\n                      \n                      ).","order":2,"name":"Ethics","label":"Institutional review board statement","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Not Applicable.","order":3,"name":"Ethics","label":"Informed consent","group":{"name":"EthicsHeading","label":"Declarations"}}],"article-number":"225"}}