{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,13]],"date-time":"2026-07-13T10:19:09Z","timestamp":1783937949511,"version":"3.55.0"},"reference-count":53,"publisher":"Springer Science and Business Media LLC","issue":"11","license":[{"start":{"date-parts":[[2023,10,20]],"date-time":"2023-10-20T00:00:00Z","timestamp":1697760000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2023,10,20]],"date-time":"2023-10-20T00:00:00Z","timestamp":1697760000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Mol Biotechnol"],"published-print":{"date-parts":[[2024,11]]},"DOI":"10.1007\/s12033-023-00931-8","type":"journal-article","created":{"date-parts":[[2023,10,20]],"date-time":"2023-10-20T05:02:02Z","timestamp":1697778122000},"page":"3238-3251","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Zoledronic Acid Accelerates Bone Healing in Carpal Navicular Fracture via Silencing Long Non-coding RNA Growth Arrest Specificity 5 to Modulate MicroRNA-29a-3p Expression"],"prefix":"10.1007","volume":"66","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1314-5746","authenticated-orcid":false,"given":"Xing","family":"Liu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"LiJun","family":"Tian","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"ZhiGang","family":"Deng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"YuSong","family":"Guo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"SanBing","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2023,10,20]]},"reference":[{"key":"931_CR1","doi-asserted-by":"publisher","first-page":"104776","DOI":"10.1016\/j.compbiomed.2021.104776","volume":"137","author":"C Chen","year":"2021","unstructured":"Chen, C., Liu, B., Zhou, K., He, W., Yan, F., Wang, Z., et al. (2021). CSR-Net: Cross-scale residual network for multi-objective scaphoid fracture segmentation. Computers in Biology and Medicine, 137, 104776.","journal-title":"Computers in Biology and Medicine"},{"issue":"11","key":"931_CR2","doi-asserted-by":"publisher","first-page":"938","DOI":"10.1007\/s00132-016-3333-y","volume":"45","author":"T Kahl","year":"2016","unstructured":"Kahl, T., Razny, F. K., Benter, J. P., Mutig, K., Hegenscheid, K., Mutze, S., et al. (2016). Diagnosis of the scaphoid bone: Fractures, nonunion, circulation, Perfusion. Orthopade, 45(11), 938\u2013944.","journal-title":"Orthopade"},{"issue":"2","key":"931_CR3","doi-asserted-by":"publisher","first-page":"165.e1","DOI":"10.1016\/j.jhsa.2018.10.018","volume":"44","author":"N Jew","year":"2019","unstructured":"Jew, N., Lipman, J. D., & Carlson, M. G. (2019). The use of three-dimensional printing for complex scaphoid fractures. The Journal of Hand Surgery, 44(2), 165.e1\u2013165.e6.","journal-title":"The Journal of Hand Surgery"},{"issue":"3","key":"931_CR4","doi-asserted-by":"publisher","first-page":"259","DOI":"10.1016\/j.hcl.2019.03.002","volume":"35","author":"MD Sabbagh","year":"2019","unstructured":"Sabbagh, M. D., Morsy, M., & Moran, S. L. (2019). Diagnosis and management of acute scaphoid fractures. Hand Clinics, 35(3), 259\u2013269.","journal-title":"Hand Clinics"},{"issue":"3","key":"931_CR5","doi-asserted-by":"publisher","first-page":"241","DOI":"10.1016\/j.hcl.2019.03.001","volume":"35","author":"KK Amrami","year":"2019","unstructured":"Amrami, K. K., Frick, M. A., & Matsumoto, J. M. (2019). Imaging for acute and chronic scaphoid fractures. Hand Clinics, 35(3), 241\u2013257.","journal-title":"Hand Clinics"},{"issue":"36","key":"931_CR6","doi-asserted-by":"publisher","first-page":"e12161","DOI":"10.1097\/MD.0000000000012161","volume":"97","author":"F Solla","year":"2018","unstructured":"Solla, F., Bougamha, W., Doria, C., Musoff, C., Bertoncelli, C. M., Rosello, O., et al. (2018). Conservative treatment of a pathologic fracture of the scaphoid bone in a child: A case report. Medicine, 97(36), e12161.","journal-title":"Medicine"},{"key":"931_CR7","doi-asserted-by":"publisher","first-page":"116161","DOI":"10.1016\/j.bone.2021.116161","volume":"153","author":"M Bevers","year":"2021","unstructured":"Bevers, M., Daniels, A. M., van Rietbergen, B., Geusens, P., van Kuijk, S. M. J., Sassen, S., et al. (2021). Assessment of the healing of conservatively-treated scaphoid fractures using HR-pQCT. Bone, 153, 116161.","journal-title":"Bone"},{"issue":"3","key":"931_CR8","first-page":"1564","volume":"25","author":"B He","year":"2021","unstructured":"He, B., Zhao, J. Q., Zhang, M. Z., & Quan, Z. X. (2021). Zoledronic acid and fracture risk: A meta-analysis of 12 randomized controlled trials. European Review for Medical and Pharmacological Sciences, 25(3), 1564\u20131573.","journal-title":"European Review for Medical and Pharmacological Sciences"},{"issue":"6","key":"931_CR9","doi-asserted-by":"publisher","first-page":"1217","DOI":"10.1007\/s00198-021-05923-5","volume":"32","author":"KW Lyles","year":"2021","unstructured":"Lyles, K. W., Bauer, D. C., Colon-Emeric, C. S., Pieper, C. F., Cummings, S. R., & Black, D. M. (2021). Zoledronic acid reduces the rate of clinical fractures after surgical repair of a hip fracture regardless of the pretreatment bone mineral density. Osteoporosis International, 32(6), 1217\u20131219.","journal-title":"Osteoporosis International"},{"issue":"3","key":"931_CR10","doi-asserted-by":"publisher","first-page":"380","DOI":"10.1111\/os.12460","volume":"11","author":"Z Liu","year":"2019","unstructured":"Liu, Z., Li, C. W., Mao, Y. F., Liu, K., Liang, B. C., Wu, L. G., et al. (2019). Study on zoledronic acid reducing acute bone loss and fracture rates in elderly postoperative patients with intertrochanteric fractures. Orthopaedic Surgery, 11(3), 380\u2013385.","journal-title":"Orthopaedic Surgery"},{"issue":"1","key":"931_CR11","doi-asserted-by":"publisher","first-page":"19","DOI":"10.1186\/s10020-021-00276-5","volume":"27","author":"W Lin","year":"2021","unstructured":"Lin, W., Li, X. F., Ren, D. C., Song, M., Duan, L., Liu, J. Z., et al. (2021). Administration of zoledronic acid alleviates osteoporosis in HIV patients by suppressing osteoclastogenesis via regulating RANKL expression. Molecular Medicine, 27(1), 19.","journal-title":"Molecular Medicine"},{"issue":"2","key":"931_CR12","first-page":"582","volume":"44","author":"XL Huang","year":"2019","unstructured":"Huang, X. L., Huang, L. Y., Cheng, Y. T., Li, F., Zhou, Q., Wu, C., et al. (2019). Zoledronic acid inhibits osteoclast differentiation and function through the regulation of NF-\u03baB and JNK signalling pathways. International Journal of Molecular Medicine, 44(2), 582\u2013592.","journal-title":"International Journal of Molecular Medicine"},{"issue":"1","key":"931_CR13","doi-asserted-by":"publisher","first-page":"1059","DOI":"10.1186\/s12885-020-07568-9","volume":"20","author":"L Wang","year":"2020","unstructured":"Wang, L., Fang, D., Xu, J., & Luo, R. (2020). Various pathways of zoledronic acid against osteoclasts and bone cancer metastasis: A brief review. Bmc Cancer, 20(1), 1059.","journal-title":"Bmc Cancer"},{"key":"931_CR14","doi-asserted-by":"publisher","first-page":"44245","DOI":"10.1038\/srep44245","volume":"7","author":"TW Tai","year":"2017","unstructured":"Tai, T. W., Chen, C. Y., Su, F. C., Tu, Y. K., Tsai, T. T., Lin, C. F., et al. (2017). Reactive oxygen species are required for zoledronic acid-induced apoptosis in osteoclast precursors and mature osteoclast-like cells. Scientific Reports, 7, 44245.","journal-title":"Scientific Reports"},{"issue":"8","key":"931_CR15","doi-asserted-by":"publisher","first-page":"4763","DOI":"10.1007\/s00520-021-06018-x","volume":"29","author":"H Ikesue","year":"2021","unstructured":"Ikesue, H., Mouri, M., Tomita, H., Hirabatake, M., Ikemura, M., Muroi, N., et al. (2021). Associated characteristics and treatment outcomes of medication-related osteonecrosis of the jaw in patients receiving denosumab or zoledronic acid for bone metastases. Supportive Care in Cancer, 29(8), 4763\u20134772.","journal-title":"Supportive Care in Cancer"},{"issue":"9","key":"931_CR16","doi-asserted-by":"publisher","first-page":"1691","DOI":"10.1089\/dna.2020.5672","volume":"39","author":"A Del Real","year":"2020","unstructured":"Del Real, A., L\u00f3pez-Delgado, L., Sa\u00f1udo, C., Garc\u00eda-Ibarbia, C., Laguna, E., Perez-Campo, F. M., et al. (2020). Long noncoding RNAs as bone marrow stem cell regulators in osteoporosis. DNA and Cell Biology, 39(9), 1691\u20131699.","journal-title":"DNA and Cell Biology"},{"issue":"1","key":"931_CR17","doi-asserted-by":"publisher","first-page":"133","DOI":"10.1007\/s13577-021-00629-6","volume":"35","author":"Y Zhang","year":"2022","unstructured":"Zhang, Y., Yuan, Q., Wei, Q., Li, P., Zhuang, Z., Li, J., et al. (2022). Long noncoding RNA XIST modulates microRNA-135\/CREB1 axis to influence osteogenic differentiation of osteoblast-like cells in mice with tibial fracture healing. Human Cell, 35(1), 133\u2013149.","journal-title":"Human Cell"},{"issue":"1","key":"931_CR18","doi-asserted-by":"publisher","first-page":"271","DOI":"10.1186\/s13075-019-2033-5","volume":"21","author":"H Chen","year":"2019","unstructured":"Chen, H., Yang, S., & Shao, R. (2019). Long non-coding XIST raises methylation of TIMP-3 promoter to regulate collagen degradation in osteoarthritic chondrocytes after tibial plateau fracture. Arthritis Research & Therapy, 21(1), 271.","journal-title":"Arthritis Research & Therapy"},{"issue":"7","key":"931_CR19","doi-asserted-by":"publisher","first-page":"1460","DOI":"10.7150\/ijbs.33529","volume":"15","author":"X Zhang","year":"2019","unstructured":"Zhang, X., Du, K., Lou, Z., Ding, K., Zhang, F., Zhu, J., et al. (2019). The CtBP1-HDAC1\/2-IRF1 transcriptional complex represses the expression of the long noncoding RNA GAS5 in human osteosarcoma cells. International Journal of Biological Sciences, 15(7), 1460\u20131471.","journal-title":"International Journal of Biological Sciences"},{"key":"931_CR20","doi-asserted-by":"publisher","first-page":"701","DOI":"10.3389\/fphar.2020.00701","volume":"11","author":"Q Yang","year":"2020","unstructured":"Yang, Q., Han, Y., Liu, P., Huang, Y., Li, X., Jia, L., et al. (2020). Long noncoding RNA GAS5 promotes osteogenic differentiation of human periodontal ligament stem cells by regulating GDF5 and p38\/JNK signaling pathway. Frontiers in Pharmacology, 11, 701.","journal-title":"Frontiers in Pharmacology"},{"issue":"18","key":"931_CR21","doi-asserted-by":"publisher","first-page":"6930","DOI":"10.3390\/ijms21186930","volume":"21","author":"VV Visconti","year":"2020","unstructured":"Visconti, V. V., Fittipaldi, S., Ciuffi, S., Marini, F., Isaia, G., & D\u2019Amelio, P. (2020). Circulating long non-coding RNA GAS5 Is overexpressed in serum from osteoporotic patients and is associated with increased risk of bone fragility. International Journal Of Molecular Sciences, 21(18), 6930.","journal-title":"International Journal Of Molecular Sciences"},{"issue":"4","key":"931_CR22","doi-asserted-by":"publisher","first-page":"777","DOI":"10.1016\/j.bone.2011.07.005","volume":"49","author":"Y Doi","year":"2011","unstructured":"Doi, Y., Miyazaki, M., Yoshiiwa, T., Hara, K., Kataoka, M., & Tsumura, H. (2011). Manipulation of the anabolic and catabolic responses with BMP-2 and zoledronic acid in a rat femoral fracture model. Bone, 49(4), 777\u2013782.","journal-title":"Bone"},{"issue":"8","key":"931_CR23","first-page":"851","volume":"32","author":"H Liu","year":"2017","unstructured":"Liu, H., Li, W., Jia, S., & Li, B. (2017). Puerarin and zinc additively prevent mandibular bone loss through inhibiting osteoclastogenesis in ovariectomized rats. Histology and Histopathology, 32(8), 851\u2013860.","journal-title":"Histology and Histopathology"},{"key":"931_CR24","doi-asserted-by":"publisher","first-page":"153340","DOI":"10.1016\/j.prp.2021.153340","volume":"219","author":"J Zhang","year":"2021","unstructured":"Zhang, J., Zhang, T., Tang, B., Li, J., & Zha, Z. (2021). The miR-187 induced bone reconstruction and healing in a mouse model of osteoporosis, and accelerated osteoblastic differentiation of human multipotent stromal cells by targeting BARX2. Pathology, Research and Practice, 219, 153340.","journal-title":"Pathology, Research and Practice"},{"issue":"5","key":"931_CR25","doi-asserted-by":"publisher","first-page":"BSR20193436","DOI":"10.1042\/BSR20193436","volume":"40","author":"G Cao","year":"2020","unstructured":"Cao, G., Meng, X., Han, X., & Li, J. (2020). Exosomes derived from circRNA Rtn4-modified BMSCs attenuate TNF-\u03b1-induced cytotoxicity and apoptosis in murine MC3T3-E1 cells by sponging miR-146a. Bioscience Reports, 40(5), BSR20193436.","journal-title":"Bioscience Reports"},{"issue":"2","key":"931_CR26","doi-asserted-by":"publisher","first-page":"299","DOI":"10.1038\/ijo.2016.189","volume":"41","author":"J Chen","year":"2017","unstructured":"Chen, J., Liu, Y., Lu, S., Yin, L., Zong, C., Cui, S., et al. (2017). The role and possible mechanism of lncRNA U90926 in modulating 3T3-L1 preadipocyte differentiation. International journal of obesity, 41(2), 299\u2013308.","journal-title":"International journal of obesity"},{"issue":"4","key":"931_CR27","doi-asserted-by":"publisher","first-page":"252","DOI":"10.1038\/s41419-019-1479-3","volume":"10","author":"CC Zhao","year":"2019","unstructured":"Zhao, C. C., Jiao, Y., Zhang, Y. Y., Ning, J., Zhang, Y. R., Xu, J., et al. (2019). Lnc SMAD5-AS1 as ceRNA inhibit proliferation of diffuse large B cell lymphoma via Wnt\/\u03b2-catenin pathway by sponging miR-135b-5p to elevate expression of APC. Cell Death and Disease, 10(4), 252.","journal-title":"Cell Death and Disease"},{"key":"931_CR28","first-page":"6697749","volume":"2021","author":"Z Wang","year":"2021","unstructured":"Wang, Z., Zhou, Y., Dai, Z., Chen, X., Li, C., Lin, Z., et al. (2021). A Novel Long Noncoding RNA, Lnc-OAD, is required for bone morphogenetic protein 2- (BMP-2-) Induced osteoblast differentiation. Biomed Research International, 2021, 6697749.","journal-title":"Biomed Research International"},{"issue":"3","key":"931_CR29","doi-asserted-by":"publisher","first-page":"103949","DOI":"10.1016\/j.isci.2022.103949","volume":"25","author":"C Yin","year":"2022","unstructured":"Yin, C., Tian, Y., Li, D., Yu, Y., Jiang, S., Hou, Y., et al. (2022). Long noncoding RNA Lnc-DIF inhibits bone formation by sequestering miR-489-3p. iScience, 25(3), 103949.","journal-title":"iScience"},{"issue":"11","key":"931_CR30","doi-asserted-by":"publisher","first-page":"5585","DOI":"10.7150\/thno.54477","volume":"11","author":"D Li","year":"2021","unstructured":"Li, D., Liu, J., Yang, C., Tian, Y., Yin, C., Hu, L., et al. (2021). Targeting long noncoding RNA PMIF facilitates osteoprogenitor cells migrating to bone formation surface to promote bone formation during aging. Theranostics, 11(11), 5585\u20135604.","journal-title":"Theranostics"},{"issue":"1","key":"931_CR31","doi-asserted-by":"publisher","first-page":"83","DOI":"10.1002\/cbin.11470","volume":"45","author":"F Wu","year":"2021","unstructured":"Wu, F., Huang, W., Yang, Y., Liu, F., Chen, J., Wang, G., et al. (2021). Mir-155-5p regulates mesenchymal stem cell osteogenesis and proliferation by targeting GSK3B in steroid-associated osteonecrosis. Cell Biology International, 45(1), 83\u201391.","journal-title":"Cell Biology International"},{"issue":"12","key":"931_CR32","doi-asserted-by":"publisher","first-page":"2938","DOI":"10.1002\/jcb.25241","volume":"116","author":"MA Schoeman","year":"2015","unstructured":"Schoeman, M. A., Moester, M. J., Oostlander, A. E., Kaijzel, E. L., Valstar, E. R., Nelissen, R. G., et al. (2015). Inhibition of GSK3\u03b2 stimulates BMP signaling and decreases SOST expression which results in enhanced osteoblast differentiation. Journal of Cellular Biochemistry, 116(12), 2938\u20132946.","journal-title":"Journal of Cellular Biochemistry"},{"issue":"20","key":"931_CR33","first-page":"6616","volume":"22","author":"SL Tang","year":"2018","unstructured":"Tang, S. L., Huang, Q. H., Wu, L. G., Liu, C., & Cai, A. L. (2018). MiR-124 regulates osteoblast differentiation through GSK-3\u03b2 in ankylosing spondylitis. European Review for Medical and Pharmacological Sciences, 22(20), 6616\u20136624.","journal-title":"European Review for Medical and Pharmacological Sciences"},{"issue":"8","key":"931_CR34","doi-asserted-by":"publisher","first-page":"13602","DOI":"10.1002\/jcp.28039","volume":"234","author":"H Ida-Yonemochi","year":"2019","unstructured":"Ida-Yonemochi, H., Nakagawa, E., Takata, H., Furuyashiki, T., Kakutani, R., Tanaka, M., et al. (2019). Extracellular enzymatically synthesized glycogen promotes osteogenesis by activating osteoblast differentiation via Akt\/GSK-3\u03b2 signaling pathway. Journal of Cellular Physiology, 234(8), 13602\u201313616.","journal-title":"Journal of Cellular Physiology"},{"key":"931_CR35","doi-asserted-by":"publisher","first-page":"78","DOI":"10.1016\/j.bone.2016.03.011","volume":"87","author":"M Hadjiargyrou","year":"2016","unstructured":"Hadjiargyrou, M., Zhi, J., & Komatsu, D. E. (2016). Identification of the microRNA transcriptome during the early phases of mammalian fracture repair. Bone, 87, 78\u201388.","journal-title":"Bone"},{"issue":"1","key":"931_CR36","doi-asserted-by":"publisher","first-page":"686","DOI":"10.1111\/jcmm.14777","volume":"24","author":"C Jiang","year":"2020","unstructured":"Jiang, C., Xia, W., Wu, T., Pan, C., Shan, H., Wang, F., et al. (2020). Inhibition of microRNA-222 up-regulates TIMP3 to promotes osteogenic differentiation of MSCs from fracture rats with type 2 diabetes mellitus. Journal of Cellular and Molecular Medicine, 24(1), 686\u2013694.","journal-title":"Journal of Cellular and Molecular Medicine"},{"issue":"2","key":"931_CR37","doi-asserted-by":"publisher","first-page":"555","DOI":"10.1159\/000492993","volume":"49","author":"Y Cui","year":"2018","unstructured":"Cui, Y., Fu, S., Hou, T., & Wu, X. (2018). Endothelial progenitor cells enhance the Migration and Osteoclastic differentiation of bone marrow-derived Macrophages in vitro and in a mouse femur fracture model through Talin-1. Cellular Physiology and Biochemistry, 49(2), 555\u2013564.","journal-title":"Cellular Physiology and Biochemistry"},{"issue":"1","key":"931_CR38","first-page":"89","volume":"33","author":"P Cui","year":"2018","unstructured":"Cui, P., Liu, H., Sun, J., Amizuka, N., Sun, Q., & Li, M. (2018). Zoledronate promotes bone formation by blocking osteocyte-osteoblast communication during bone defect healing. Histology and Histopathology, 33(1), 89\u201399.","journal-title":"Histology and Histopathology"},{"key":"931_CR39","doi-asserted-by":"publisher","first-page":"166","DOI":"10.1016\/j.bone.2014.07.003","volume":"67","author":"TW Tai","year":"2014","unstructured":"Tai, T. W., Su, F. C., Chen, C. Y., Jou, I. M., & Lin, C. F. (2014). Activation of p38 MAPK-regulated Bcl-xL signaling increases survival against zoledronic acid-induced apoptosis in osteoclast precursors. Bone, 67, 166\u2013174.","journal-title":"Bone"},{"issue":"6","key":"931_CR40","doi-asserted-by":"publisher","first-page":"927","DOI":"10.3390\/biom10060927","volume":"10","author":"S Donati","year":"2020","unstructured":"Donati, S., Ciuffi, S., Palmini, G., & Brandi, M. L. (2020). Circulating miRNAs: A new opportunity in bone fragility. Biomolecules, 10(6), 927.","journal-title":"Biomolecules"},{"issue":"3","key":"931_CR41","doi-asserted-by":"publisher","first-page":"389","DOI":"10.1002\/jbmr.3194","volume":"33","author":"DM Black","year":"2018","unstructured":"Black, D. M., Cauley, J. A., Wagman, R., Ensrud, K., Fink, H. A., Hillier, T. A., et al. (2018). The ability of a single BMD and fracture history assessment to predict fracture over 25 years in postmenopausal women: The study of osteoporotic fractures. Journal of Bone and Mineral Research, 33(3), 389\u2013395.","journal-title":"Journal of Bone and Mineral Research"},{"issue":"Suppl 8","key":"931_CR42","first-page":"S16","volume":"98","author":"S Buranasinsup","year":"2015","unstructured":"Buranasinsup, S., & Bunyaratavej, N. (2015). The Intriguing correlation between undercarboxylated osteocalcin and vitamin D. Journal of the Medical Association of Thailand, 98(Suppl 8), S16\u201320.","journal-title":"Journal of the Medical Association of Thailand"},{"key":"931_CR43","doi-asserted-by":"publisher","first-page":"56","DOI":"10.1016\/j.abb.2014.07.020","volume":"561","author":"ML Cancela","year":"2014","unstructured":"Cancela, M. L., Laiz\u00e9, V., & Concei\u00e7\u00e3o, N. (2014). Matrix gla protein and osteocalcin: From gene duplication to neofunctionalization. Archives of Biochemistry and Biophysics, 561, 56\u201363.","journal-title":"Archives of Biochemistry and Biophysics"},{"issue":"5","key":"931_CR44","doi-asserted-by":"publisher","first-page":"1431","DOI":"10.1210\/jcem-70-5-1431","volume":"70","author":"HK Nielsen","year":"1990","unstructured":"Nielsen, H. K., Brixen, K., Bouillon, R., & Mosekilde, L. (1990). Changes in biochemical markers of osteoblastic activity during the menstrual cycle. Journal of Clinical Endocrinology and Metabolism, 70(5), 1431\u20131437.","journal-title":"Journal of Clinical Endocrinology and Metabolism"},{"issue":"3","key":"931_CR45","doi-asserted-by":"publisher","first-page":"1094","DOI":"10.1039\/C6FO01346E","volume":"8","author":"Q Zhan","year":"2017","unstructured":"Zhan, Q., Gui, X., Wang, F., Yu, P., Zhao, M., Wang, J., et al. (2017). Sialoglycoprotein isolated from the eggs of Gadus morhua enhances fracture healing in osteoporotic mice. Food & Function, 8(3), 1094\u20131104.","journal-title":"Food & Function"},{"issue":"10","key":"931_CR46","doi-asserted-by":"publisher","first-page":"2224","DOI":"10.1080\/07391102.2016.1214083","volume":"35","author":"T Kausar","year":"2017","unstructured":"Kausar, T., & Nayeem, S. M. (2017). Computational analysis on conformational dynamics of bone morphogenetic protein-2 (BMP-2). Journal of Biomolecular Structure & Dynamics, 35(10), 2224\u20132234.","journal-title":"Journal of Biomolecular Structure & Dynamics"},{"issue":"1","key":"931_CR47","doi-asserted-by":"publisher","first-page":"19637","DOI":"10.1038\/s41598-021-98916-7","volume":"11","author":"Y Bai","year":"2021","unstructured":"Bai, Y., Liu, X., Chen, Q., Chen, T., Jiang, N., & Guo, Z. (2021). Myricetin ameliorates ox-LDL-induced HUVECs apoptosis and inflammation via lncRNA GAS5 upregulating the expression of miR-29a-3p. Scientific Reports, 11(1), 19637.","journal-title":"Scientific Reports"},{"issue":"19","key":"931_CR48","doi-asserted-by":"publisher","first-page":"5558","DOI":"10.7150\/thno.34463","volume":"9","author":"X He","year":"2019","unstructured":"He, X., Wang, S., Li, M., Zhong, L., Zheng, H., Sun, Y., et al. (2019). Long noncoding RNA GAS5 induces abdominal aortic aneurysm formation by promoting smooth muscle apoptosis. Theranostics, 9(19), 5558\u20135576.","journal-title":"Theranostics"},{"issue":"8","key":"931_CR49","doi-asserted-by":"publisher","first-page":"1285","DOI":"10.3727\/096504018X15166193231711","volume":"26","author":"W Li","year":"2018","unstructured":"Li, W., Zhao, W., Lu, Z., Zhang, W., & Yang, X. (2018). Long noncoding RNA GAS5 promotes proliferation, Migration, and Invasion by Regulation of miR-301a in Esophageal Cancer. Oncology Research, 26(8), 1285\u20131294.","journal-title":"Oncology Research"},{"key":"931_CR50","doi-asserted-by":"publisher","first-page":"97","DOI":"10.1016\/j.mce.2016.04.014","volume":"430","author":"WY Lee","year":"2016","unstructured":"Lee, W. Y., Li, N., Lin, S., Wang, B., Lan, H. Y., & Li, G. (2016). miRNA-29b improves bone healing in mouse fracture model. Molecular and Cellular Endocrinology, 430, 97\u2013107.","journal-title":"Molecular and Cellular Endocrinology"},{"key":"931_CR51","doi-asserted-by":"publisher","first-page":"115105","DOI":"10.1016\/j.bone.2019.115105","volume":"130","author":"P Zarecki","year":"2020","unstructured":"Zarecki, P., Hackl, M., Grillari, J., Debono, M., & Eastell, R. (2020). Serum microRNAs as novel biomarkers for osteoporotic vertebral fractures. Bone, 130, 115105.","journal-title":"Bone"},{"issue":"6","key":"931_CR52","doi-asserted-by":"publisher","first-page":"1045","DOI":"10.1007\/s13770-021-00384-7","volume":"18","author":"Q Wang","year":"2021","unstructured":"Wang, Q., Chen, Y., Shen, X., Chen, J., & Li, Y. (2021). Intra-articular injection of miR-29a-3p of BMSCs promotes cartilage self-repairing and alleviates Pain in the Rat Osteoarthritis. Tissue Engineering and Regenerative Medicine, 18(6), 1045\u20131055.","journal-title":"Tissue Engineering and Regenerative Medicine"},{"issue":"4","key":"931_CR53","doi-asserted-by":"publisher","first-page":"3155","DOI":"10.4081\/ejh.2020.3155","volume":"64","author":"Z Li","year":"2020","unstructured":"Li, Z., Hong, Z., Zheng, Y., Dong, Y., He, W., & Yuan, Y. (2020). An emerging potential therapeutic target for osteoporosis: LncRNA H19\/miR-29a-3p axis. European Journal Of Histochemistry, 64(4), 3155.","journal-title":"European Journal Of Histochemistry"}],"container-title":["Molecular Biotechnology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12033-023-00931-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s12033-023-00931-8\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12033-023-00931-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,11,8]],"date-time":"2024-11-08T07:19:23Z","timestamp":1731050363000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s12033-023-00931-8"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,10,20]]},"references-count":53,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2024,11]]}},"alternative-id":["931"],"URL":"https:\/\/doi.org\/10.1007\/s12033-023-00931-8","relation":{},"ISSN":["1073-6085","1559-0305"],"issn-type":[{"value":"1073-6085","type":"print"},{"value":"1559-0305","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,10,20]]},"assertion":[{"value":"23 March 2023","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"5 October 2023","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"20 October 2023","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Authors declared no conflict of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"All procedures and animal care were approved by The Third Hospital of ShiJiaZhuang Animal Care Committee and performed according to NIH guidelines (Ethics approval number: SJZ2017T03618).","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical Approval"}}]}}