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All experiments and procedures were reviewed and approved by the ethics committee of the Sun Yat-sen University First Affiliated Hospital (Guangzhou, China). All efforts were made to minimize the suffering of the animals during experiments.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics Approval and Consent to Participate"}},{"value":"Not applicable.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for Publication"}}]}}