{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T08:06:53Z","timestamp":1791965213079,"version":"4.3.4"},"reference-count":78,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2012,10,14]],"date-time":"2012-10-14T00:00:00Z","timestamp":1350172800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Mol Neurobiol"],"published-print":{"date-parts":[[2013,2]]},"DOI":"10.1007\/s12035-012-8350-1","type":"journal-article","created":{"date-parts":[[2012,10,17]],"date-time":"2012-10-17T16:41:26Z","timestamp":1350492086000},"page":"290-301","source":"Crossref","is-referenced-by-count":38,"title":["Nuclear Lamins in the Brain \u2014 New Insights into Function and Regulation"],"prefix":"10.1007","volume":"47","author":[{"given":"Hea-Jin","family":"Jung","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John M.","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shao H.","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephen G.","family":"Young","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Loren G.","family":"Fong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2012,10,14]]},"reference":[{"key":"8350_CR1","doi-asserted-by":"crossref","first-page":"2157","DOI":"10.1016\/j.yexcr.2007.03.004","volume":"313","author":"S Melcer","year":"2007","unstructured":"Melcer S, Gruenbaum Y, Krohne G (2007) Invertebrate lamins. Exp Cell Res 313:2157\u20132166. doi: 10.1016\/j.yexcr.2007.03.004","journal-title":"Exp Cell Res"},{"key":"8350_CR2","doi-asserted-by":"crossref","first-page":"967","DOI":"10.1152\/physrev.00047.2005","volume":"86","author":"JL Broers","year":"2006","unstructured":"Broers JL, Ramaekers FC, Bonne G, Yaou RB, Hutchison CJ (2006) Nuclear lamins: laminopathies and their role in premature ageing. Physiol Rev 86:967\u20131008. doi: 10.1152\/physrev.00047.2005","journal-title":"Physiol Rev"},{"key":"8350_CR3","doi-asserted-by":"crossref","first-page":"316","DOI":"10.1002\/path.2999","volume":"226","author":"HJ Worman","year":"2012","unstructured":"Worman HJ (2012) Nuclear lamins and laminopathies. J Pathol 226:316\u2013325. doi: 10.1002\/path.2999","journal-title":"J Pathol"},{"key":"8350_CR4","doi-asserted-by":"crossref","first-page":"222","DOI":"10.1186\/gb-2011-12-5-222","volume":"12","author":"TA Dittmer","year":"2011","unstructured":"Dittmer TA, Misteli T (2011) The lamin protein family. Genome Biol 12:222. doi: 10.1186\/gb-2011-12-5-222","journal-title":"Genome Biol"},{"key":"8350_CR5","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1242\/dev.105.2.365","volume":"105","author":"RA Rober","year":"1989","unstructured":"Rober RA, Weber K, Osborn M (1989) Differential timing of nuclear lamin A\/C expression in the various organs of the mouse embryo and the young animal: a developmental study. Development 105:365\u2013378","journal-title":"Development"},{"key":"8350_CR6","doi-asserted-by":"crossref","first-page":"1099","DOI":"10.1083\/jcb.105.3.1099","volume":"105","author":"S Lebel","year":"1987","unstructured":"Lebel S, Lampron C, Royal A, Raymond Y (1987) Lamins A and C appear during retinoic acid-induced differentiation of mouse embryonal carcinoma cells. J Cell Biol 105:1099\u20131104","journal-title":"J Cell Biol"},{"key":"8350_CR7","doi-asserted-by":"crossref","first-page":"16321","DOI":"10.1016\/S0021-9258(19)85424-8","volume":"268","author":"F Lin","year":"1993","unstructured":"Lin F, Worman HJ (1993) Structural organization of the human gene encoding nuclear lamin A and nuclear lamin C. J Biol Chem 268:16321\u201316326","journal-title":"J Biol Chem"},{"key":"8350_CR8","doi-asserted-by":"crossref","first-page":"230","DOI":"10.1006\/geno.1995.1036","volume":"27","author":"F Lin","year":"1995","unstructured":"Lin F, Worman HJ (1995) Structural organization of the human gene (LMNB1) encoding nuclear lamin B1. Genomics 27:230\u2013236. doi: 10.1006\/geno.1995.1036","journal-title":"Genomics"},{"key":"8350_CR9","doi-asserted-by":"crossref","first-page":"3499","DOI":"10.1128\/MCB.12.8.3499","volume":"12","author":"G Biamonti","year":"1992","unstructured":"Biamonti G, Giacca M, Perini G, Contreas G, Zentilin L, Weighardt F, Guerra M, Della Valle G, Saccone S, Riva S et al (1992) The gene for a novel human lamin maps at a highly transcribed locus of chromosome 19 which replicates at the onset of S-phase. Mol Cell Biol 12:3499\u20133506","journal-title":"Mol Cell Biol"},{"key":"8350_CR10","doi-asserted-by":"crossref","first-page":"260","DOI":"10.1007\/PL00006548","volume":"49","author":"A Erber","year":"1999","unstructured":"Erber A, Riemer D, Hofemeister H, Bovenschulte M, Stick R, Panopoulou G, Lehrach H, Weber K (1999) Characterization of the Hydra lamin and its gene: a molecular phylogeny of metazoan lamins. J Mol Evol 49:260\u2013271. doi: 10.1007\/PL00006548","journal-title":"J Mol Evol"},{"key":"8350_CR11","first-page":"21","volume-title":"The enzymes","author":"BS Davies","year":"2011","unstructured":"Davies BS, Coffinier C, Yang SH, Jung HJ, Fong LG, Young SG (2011) Posttranslational processing of nuclear lamins. In: Tamanoi F, Hrycyna CA, Bergo MO (eds) The enzymes. Elsevier, Amsterdam, pp 21\u201341"},{"key":"8350_CR12","doi-asserted-by":"crossref","first-page":"6450","DOI":"10.1073\/pnas.83.17.6450","volume":"83","author":"DZ Fisher","year":"1986","unstructured":"Fisher DZ, Chaudhary N, Blobel G (1986) cDNA sequencing of nuclear lamins A and C reveals primary and secondary structural homology to intermediate filament proteins. Proc Natl Acad Sci U S A 83:6450\u20136454","journal-title":"Proc Natl Acad Sci U S A"},{"key":"8350_CR13","doi-asserted-by":"crossref","first-page":"463","DOI":"10.1038\/319463a0","volume":"319","author":"FD McKeon","year":"1986","unstructured":"McKeon FD, Kirschner MW, Caput D (1986) Homologies in both primary and secondary structure between nuclear envelope and intermediate filament proteins. Nature 319:463\u2013468. doi: 10.1038\/319463a0","journal-title":"Nature"},{"key":"8350_CR14","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1016\/1047-8477(92)90009-Y","volume":"108","author":"E Heitlinger","year":"1992","unstructured":"Heitlinger E, Peter M, Lustig A, Villiger W, Nigg EA, Aebi U (1992) The role of the head and tail domain in lamin structure and assembly: analysis of bacterially expressed chicken lamin A and truncated B2 lamins. J Struct Biol 108:74\u201389. doi: 1047-8477(92)90009-Y","journal-title":"J Struct Biol"},{"key":"8350_CR15","doi-asserted-by":"crossref","first-page":"913","DOI":"10.1083\/jcb.147.5.913","volume":"147","author":"T Sullivan","year":"1999","unstructured":"Sullivan T, Escalante-Alcalde D, Bhatt H, Anver M, Bhat N, Nagashima K, Stewart CL, Burke B (1999) Loss of A-type lamin expression compromises nuclear envelope integrity leading to muscular dystrophy. J Cell Biol 147:913\u2013920","journal-title":"J Cell Biol"},{"key":"8350_CR16","doi-asserted-by":"crossref","first-page":"370","DOI":"10.1172\/JCI200419670","volume":"113","author":"J Lammerding","year":"2004","unstructured":"Lammerding J, Schulze PC, Takahashi T, Kozlov S, Sullivan T, Kamm RD, Stewart CL, Lee RT (2004) Lamin A\/C deficiency causes defective nuclear mechanics and mechanotransduction. J Clin Invest 113:370\u2013378. doi: 10.1172\/JCI19670","journal-title":"J Clin Invest"},{"key":"8350_CR17","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1038\/ng1294-323","volume":"8","author":"S Bione","year":"1994","unstructured":"Bione S, Maestrini E, Rivella S, Mancini M, Regis S, Romeo G, Toniolo D (1994) Identification of a novel X-linked gene responsible for Emery\u2013Dreifuss muscular dystrophy. Nat Genet 8:323\u2013327. doi: 10.1038\/ng1294-323","journal-title":"Nat Genet"},{"issue":"Pt 6","key":"8350_CR18","doi-asserted-by":"crossref","first-page":"781","DOI":"10.1242\/jcs.111.6.781","volume":"111","author":"JA Ellis","year":"1998","unstructured":"Ellis JA, Craxton M, Yates JR, Kendrick-Jones J (1998) Aberrant intracellular targeting and cell cycle-dependent phosphorylation of emerin contribute to the Emery\u2013Dreifuss muscular dystrophy phenotype. J Cell Sci 111(Pt 6):781\u2013792","journal-title":"J Cell Sci"},{"key":"8350_CR19","doi-asserted-by":"crossref","first-page":"1825","DOI":"10.1172\/JCI37679","volume":"119","author":"HJ Worman","year":"2009","unstructured":"Worman HJ, Fong LG, Muchir A, Young SG (2009) Laminopathies and the long strange trip from basic cell biology to therapy. J Clin Invest 119:1825\u20131836. doi: 10.1172\/JCI37679","journal-title":"J Clin Invest"},{"key":"8350_CR20","doi-asserted-by":"crossref","first-page":"743","DOI":"10.1172\/JCI27125","volume":"116","author":"LG Fong","year":"2006","unstructured":"Fong LG, Ng JK, Lammerding J, Vickers TA, Meta M, Cote N, Gavino B, Qiao X, Chang SY, Young SR, Yang SH, Stewart CL, Lee RT, Bennett CF, Bergo MO, Young SG (2006) Prelamin A and lamin A appear to be dispensable in the nuclear lamina. J Clin Invest 116:743\u2013752. doi: 10.1172\/JCI27125","journal-title":"J Clin Invest"},{"key":"8350_CR21","doi-asserted-by":"crossref","first-page":"20818","DOI":"10.1074\/jbc.M110.128835","volume":"285","author":"C Coffinier","year":"2010","unstructured":"Coffinier C, Jung HJ, Li Z, Nobumori C, Yun UJ, Farber EA, Davies BS, Weinstein MM, Yang SH, Lammerding J, Farahani JN, Bentolila LA, Fong LG, Young SG (2010) Direct synthesis of lamin A, bypassing prelamin a processing, causes misshapen nuclei in fibroblasts but no detectable pathology in mice. J Biol Chem 285:20818\u201320826. doi: 10.1074\/jbc.M110.128835","journal-title":"J Biol Chem"},{"key":"8350_CR22","doi-asserted-by":"crossref","first-page":"2682","DOI":"10.1093\/hmg\/ddq158","volume":"19","author":"BS Davies","year":"2010","unstructured":"Davies BS, Barnes RH 2nd, Tu Y, Ren S, Andres DA, Spielmann HP, Lammerding J, Wang Y, Young SG, Fong LG (2010) An accumulation of non-farnesylated prelamin A causes cardiomyopathy but not progeria. Hum Mol Genet 19:2682\u20132694. doi: 10.1093\/hmg\/ddq158","journal-title":"Hum Mol Genet"},{"key":"8350_CR23","doi-asserted-by":"crossref","first-page":"4","DOI":"10.4161\/nucl.2.1.13723","volume":"2","author":"BS Davies","year":"2011","unstructured":"Davies BS, Coffinier C, Yang SH, Barnes RH 2nd, Jung HJ, Young SG, Fong LG (2011) Investigating the purpose of prelamin A processing. Nucleus 2:4\u20139. doi: 10.4161\/nucl.2.1.13723","journal-title":"Nucleus"},{"key":"8350_CR24","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1146\/annurev-genom-082908-150150","volume":"10","author":"BS Davies","year":"2009","unstructured":"Davies BS, Fong LG, Yang SH, Coffinier C, Young SG (2009) The posttranslational processing of prelamin A and disease. Annu Rev Genomics Hum Genet 10:153\u2013174. doi: 10.1146\/annurev-genom-082908-150150","journal-title":"Annu Rev Genomics Hum Genet"},{"issue":"Pt 4","key":"8350_CR25","doi-asserted-by":"crossref","first-page":"1019","DOI":"10.1242\/jcs.107.4.1019","volume":"107","author":"H Hennekes","year":"1994","unstructured":"Hennekes H, Nigg EA (1994) The role of isoprenylation in membrane attachment of nuclear lamins. A single point mutation prevents proteolytic cleavage of the lamin A precursor and confers membrane binding properties. J Cell Sci 107(Pt 4):1019\u20131029","journal-title":"J Cell Sci"},{"key":"8350_CR26","doi-asserted-by":"crossref","first-page":"13049","DOI":"10.1073\/pnas.192460799","volume":"99","author":"MO Bergo","year":"2002","unstructured":"Bergo MO, Gavino B, Ross J, Schmidt WK, Hong C, Kendall LV, Mohr A, Meta M, Genant H, Jiang Y, Wisner ER, Van Bruggen N, Carano RA, Michaelis S, Griffey SM, Young SG (2002) Zmpste24 deficiency in mice causes spontaneous bone fractures, muscle weakness, and a prelamin A processing defect. Proc Natl Acad Sci U S A 99:13049\u201313054. doi: 10.1073\/pnas.192460799","journal-title":"Proc Natl Acad Sci U S A"},{"key":"8350_CR27","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1038\/ng871","volume":"31","author":"AM Pendas","year":"2002","unstructured":"Pendas AM, Zhou Z, Cadinanos J, Freije JM, Wang J, Hultenby K, Astudillo A, Wernerson A, Rodriguez F, Tryggvason K, Lopez-Otin C (2002) Defective prelamin A processing and muscular and adipocyte alterations in Zmpste24 metalloproteinase-deficient mice. Nat Genet 31:94\u201399. doi: 10.1038\/ng871","journal-title":"Nat Genet"},{"key":"8350_CR28","doi-asserted-by":"crossref","first-page":"913","DOI":"10.1111\/j.0022-202X.2005.23846.x","volume":"125","author":"CL Moulson","year":"2005","unstructured":"Moulson CL, Go G, Gardner JM, van der Wal AC, Smitt JH, van Hagen JM, Miner JH (2005) Homozygous and compound heterozygous mutations in ZMPSTE24 cause the laminopathy restrictive dermopathy. J Invest Dermatol 125:913\u2013919. doi: 10.1111\/j.0022-202X.2005.23846.x","journal-title":"J Invest Dermatol"},{"key":"8350_CR29","doi-asserted-by":"crossref","first-page":"1503","DOI":"10.1093\/hmg\/ddi159","volume":"14","author":"CL Navarro","year":"2005","unstructured":"Navarro CL, Cadinanos J, De Sandre-Giovannoli A, Bernard R, Courrier S, Boccaccio I, Boyer A, Kleijer WJ, Wagner A, Giuliano F, Beemer FA, Freije JM, Cau P, Hennekam RC, Lopez-Otin C, Badens C, Levy N (2005) Loss of ZMPSTE24 (FACE-1) causes autosomal recessive restrictive dermopathy and accumulation of Lamin A precursors. Hum Mol Genet 14:1503\u20131513. doi: 10.1093\/hmg\/ddi159","journal-title":"Hum Mol Genet"},{"key":"8350_CR30","doi-asserted-by":"crossref","first-page":"18111","DOI":"10.1073\/pnas.0408558102","volume":"101","author":"LG Fong","year":"2004","unstructured":"Fong LG, Ng JK, Meta M, Cote N, Yang SH, Stewart CL, Sullivan T, Burghardt A, Majumdar S, Reue K, Bergo MO, Young SG (2004) Heterozygosity for Lmna deficiency eliminates the progeria-like phenotypes in Zmpste24-deficient mice. Proc Natl Acad Sci U S A 101:18111\u201318116. doi: 10.1073\/pnas.0408558102","journal-title":"Proc Natl Acad Sci U S A"},{"key":"8350_CR31","doi-asserted-by":"crossref","first-page":"2055","DOI":"10.1126\/science.1084125","volume":"300","author":"A Sandre-Giovannoli De","year":"2003","unstructured":"De Sandre-Giovannoli A, Bernard R, Cau P, Navarro C, Amiel J, Boccaccio I, Lyonnet S, Stewart CL, Munnich A, Le Merrer M, Levy N (2003) Lamin a truncation in Hutchinson\u2013Gilford progeria. Science 300:2055. doi: 10.1126\/science.1084125","journal-title":"Science"},{"key":"8350_CR32","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1038\/nature01629","volume":"423","author":"M Eriksson","year":"2003","unstructured":"Eriksson M, Brown WT, Gordon LB, Glynn MW, Singer J, Scott L, Erdos MR, Robbins CM, Moses TY, Berglund P, Dutra A, Pak E, Durkin S, Csoka AB, Boehnke M, Glover TW, Collins FS (2003) Recurrent de novo point mutations in lamin A cause Hutchinson\u2013Gilford progeria syndrome. Nature 423:293\u2013298. doi: 10.1038\/nature01629","journal-title":"Nature"},{"key":"8350_CR33","doi-asserted-by":"crossref","first-page":"4557","DOI":"10.1242\/jcs.114.24.4557","volume":"114","author":"J Harborth","year":"2001","unstructured":"Harborth J, Elbashir SM, Bechert K, Tuschl T, Weber K (2001) Identification of essential genes in cultured mammalian cells using small interfering RNAs. J Cell Sci 114:4557\u20134565","journal-title":"J Cell Sci"},{"key":"8350_CR34","doi-asserted-by":"crossref","first-page":"1671","DOI":"10.1083\/jcb.123.6.1671","volume":"123","author":"AS Belmont","year":"1993","unstructured":"Belmont AS, Zhai Y, Thilenius A (1993) Lamin B distribution and association with peripheral chromatin revealed by optical sectioning and electron microscopy tomography. J Cell Biol 123:1671\u20131685","journal-title":"J Cell Biol"},{"key":"8350_CR35","doi-asserted-by":"crossref","first-page":"1887","DOI":"10.1126\/science.1122771","volume":"311","author":"MY Tsai","year":"2006","unstructured":"Tsai MY, Wang S, Heidinger JM, Shumaker DK, Adam SA, Goldman RD, Zheng Y (2006) A mitotic lamin B matrix induced by RanGTP required for spindle assembly. Science 311:1887\u20131893. doi: 10.1126\/science.1122771","journal-title":"Science"},{"key":"8350_CR36","doi-asserted-by":"crossref","first-page":"1201","DOI":"10.1083\/jcb.125.6.1201","volume":"125","author":"RD Moir","year":"1994","unstructured":"Moir RD, Montag-Lowy M, Goldman RD (1994) Dynamic properties of nuclear lamins: lamin B is associated with sites of DNA replication. J Cell Biol 125:1201\u20131212","journal-title":"J Cell Biol"},{"key":"8350_CR37","doi-asserted-by":"crossref","first-page":"1014","DOI":"10.1242\/jcs.020982","volume":"121","author":"CW Tang","year":"2008","unstructured":"Tang CW, Maya-Mendoza A, Martin C, Zeng K, Chen S, Feret D, Wilson SA, Jackson DA (2008) The integrity of a lamin-B1-dependent nucleoskeleton is a fundamental determinant of RNA synthesis in human cells. J Cell Sci 121:1014\u20131024. doi: 10.1242\/jcs.020982","journal-title":"J Cell Sci"},{"key":"8350_CR38","doi-asserted-by":"crossref","first-page":"3537","DOI":"10.1093\/hmg\/ddr266","volume":"20","author":"SH Yang","year":"2011","unstructured":"Yang SH, Chang SY, Yin L, Tu Y, Hu Y, Yoshinaga Y, de Jong PJ, Fong LG, Young SG (2011) An absence of both lamin B1 and lamin B2 in keratinocytes has no effect on cell proliferation or the development of skin and hair. Hum Mol Genet 20:3537\u20133544. doi: 10.1093\/hmg\/ddr266","journal-title":"Hum Mol Genet"},{"key":"8350_CR39","doi-asserted-by":"crossref","first-page":"562","DOI":"10.4161\/nucl.2.6.18085","volume":"2","author":"SH Yang","year":"2011","unstructured":"Yang SH, Jung HJ, Coffinier C, Fong LG, Young SG (2011) Are B-type lamins essential in all mammalian cells? Nucleus 2:562\u2013569. doi: 10.4161\/nucl.2.6.18085","journal-title":"Nucleus"},{"key":"8350_CR40","doi-asserted-by":"crossref","first-page":"1706","DOI":"10.1126\/science.1211222","volume":"334","author":"Y Kim","year":"2011","unstructured":"Kim Y, Sharov AA, McDole K, Cheng M, Hao H, Fan CM, Gaiano N, Ko MS, Zheng Y (2011) Mouse B-type lamins are required for proper organogenesis but not by embryonic stem cells. Science 334:1706\u20131710. doi: 10.1126\/science.1211222","journal-title":"Science"},{"key":"8350_CR41","doi-asserted-by":"crossref","first-page":"5076","DOI":"10.1073\/pnas.0908790107","volume":"107","author":"C Coffinier","year":"2010","unstructured":"Coffinier C, Chang SY, Nobumori C, Tu Y, Farber EA, Toth JI, Fong LG, Young SG (2010) Abnormal development of the cerebral cortex and cerebellum in the setting of lamin B2 deficiency. Proc Natl Acad Sci U S A 107:5076\u20135081. doi: 10.1073\/pnas.0908790107","journal-title":"Proc Natl Acad Sci U S A"},{"key":"8350_CR42","doi-asserted-by":"crossref","first-page":"4683","DOI":"10.1091\/mbc.E11-06-0504","volume":"22","author":"C Coffinier","year":"2011","unstructured":"Coffinier C, Jung HJ, Nobumori C, Chang S, Tu Y, Barnes RH 2nd, Yoshinaga Y, de Jong PJ, Vergnes L, Reue K, Fong LG, Young SG (2011) Deficiencies in lamin B1 and lamin B2 cause neurodevelopmental defects and distinct nuclear shape abnormalities in neurons. Mol Biol Cell 22:4683\u20134693. doi: 10.1091\/mbc.E11-06-0504","journal-title":"Mol Biol Cell"},{"key":"8350_CR43","doi-asserted-by":"crossref","first-page":"2639","DOI":"10.1101\/gad.1462506","volume":"20","author":"DJ Solecki","year":"2006","unstructured":"Solecki DJ, Govek EE, Tomoda T, Hatten ME (2006) Neuronal polarity in CNS development. Genes Dev 20:2639\u20132647. doi: 10.1101\/gad.1462506","journal-title":"Genes Dev"},{"key":"8350_CR44","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1016\/S0092-8674(01)00628-6","volume":"108","author":"D Salina","year":"2002","unstructured":"Salina D, Bodoor K, Eckley DM, Schroer TA, Rattner JB, Burke B (2002) Cytoplasmic dynein as a facilitator of nuclear envelope breakdown. Cell 108:97\u2013107. doi: 10.1016\/S0092-8674(01)00628-6","journal-title":"Cell"},{"key":"8350_CR45","doi-asserted-by":"crossref","first-page":"10428","DOI":"10.1073\/pnas.0401424101","volume":"101","author":"L Vergnes","year":"2004","unstructured":"Vergnes L, Peterfy M, Bergo MO, Young SG, Reue K (2004) Lamin B1 is required for mouse development and nuclear integrity. Proc Natl Acad Sci U S A 101:10428\u201310433. doi: 10.1073\/pnas.0401424101","journal-title":"Proc Natl Acad Sci U S A"},{"key":"8350_CR46","doi-asserted-by":"crossref","first-page":"6309","DOI":"10.1523\/JNEUROSCI.22-15-06309.2002","volume":"22","author":"JA Gorski","year":"2002","unstructured":"Gorski JA, Talley T, Qiu M, Puelles L, Rubenstein JL, Jones KR (2002) Cortical excitatory neurons and glia, but not GABAergic neurons, are produced in the Emx1-expressing lineage. J Neurosci 22:6309\u20136314","journal-title":"J Neurosci"},{"key":"8350_CR47","doi-asserted-by":"crossref","first-page":"E423","DOI":"10.1073\/pnas.1111780109","volume":"109","author":"HJ Jung","year":"2012","unstructured":"Jung HJ, Coffinier C, Choe Y, Beigneux AP, Davies BS, Yang SH, Barnes RH 2nd, Hong J, Sun T, Pleasure SJ, Young SG, Fong LG (2012) Regulation of prelamin A but not lamin C by miR-9, a brain-specific microRNA. Proc Natl Acad Sci U S A 109:E423\u2013E431. doi: 10.1073\/pnas.1111780109","journal-title":"Proc Natl Acad Sci U S A"},{"key":"8350_CR48","doi-asserted-by":"crossref","first-page":"752","DOI":"10.1016\/j.cell.2011.11.064","volume":"148","author":"BC Yoon","year":"2012","unstructured":"Yoon BC, Jung H, Dwivedy A, O'Hare CM, Zivraj KH, Holt CE (2012) Local translation of extranuclear lamin B promotes axon maintenance. Cell 148:752\u2013764. doi: 10.1016\/j.cell.2011.11.064","journal-title":"Cell"},{"key":"8350_CR49","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1634\/stemcells.2004-0159","volume":"24","author":"D Constantinescu","year":"2006","unstructured":"Constantinescu D, Gray HL, Sammak PJ, Schatten GP, Csoka AB (2006) Lamin A\/C expression is a marker of mouse and human embryonic stem cell differentiation. Stem Cells 24:177\u2013185. doi: 10.1634\/stemcells.2004-0159","journal-title":"Stem Cells"},{"key":"8350_CR50","doi-asserted-by":"crossref","first-page":"378","DOI":"10.1006\/excr.1997.3735","volume":"236","author":"F Lin","year":"1997","unstructured":"Lin F, Worman HJ (1997) Expression of nuclear lamins in human tissues and cancer cell lines and transcription from the promoters of the lamin A\/C and B1 genes. Exp Cell Res 236:378\u2013384. doi: 10.1006\/excr.1997.3735","journal-title":"Exp Cell Res"},{"key":"8350_CR51","doi-asserted-by":"crossref","first-page":"957","DOI":"10.1089\/dna.1998.17.957","volume":"17","author":"B Tiwari","year":"1998","unstructured":"Tiwari B, Muralikrishna B, Parnaik VK (1998) Functional analysis of the 5\u2032 promoter region of the rat lamin A gene. DNA Cell Biol 17:957\u2013965","journal-title":"DNA Cell Biol"},{"key":"8350_CR52","doi-asserted-by":"crossref","first-page":"1416","DOI":"10.1046\/j.1432-1327.2000.01135.x","volume":"267","author":"K Nakamachi","year":"2000","unstructured":"Nakamachi K, Nakajima N (2000) DNase I hypersensitive sites and transcriptional activation of the lamin A\/C gene. Eur J Biochem 267:1416\u20131422. doi: 10.1046\/j.1432-1327.2000.01135.x","journal-title":"Eur J Biochem"},{"key":"8350_CR53","doi-asserted-by":"crossref","first-page":"3940","DOI":"10.1200\/JCO.2005.11.650","volume":"23","author":"R Agrelo","year":"2005","unstructured":"Agrelo R, Setien F, Espada J, Artiga MJ, Rodriguez M, Perez-Rosado A, Sanchez-Aguilera A, Fraga MF, Piris MA, Esteller M (2005) Inactivation of the lamin A\/C gene by CpG island promoter hypermethylation in hematologic malignancies, and its association with poor survival in nodal diffuse large B-cell lymphoma. J Clin Oncol 23:3940\u20133947. doi: 10.1200\/JCO.2005.11.650","journal-title":"J Clin Oncol"},{"key":"8350_CR54","doi-asserted-by":"crossref","first-page":"350","DOI":"10.1006\/excr.1999.4396","volume":"248","author":"N Stuurman","year":"1999","unstructured":"Stuurman N, Delbecque JP, Callaerts P, Aebi U (1999) Ectopic overexpression of Drosophila lamin C is stage-specific lethal. Exp Cell Res 248:350\u2013357. doi: 10.1006\/excr.1999.4396","journal-title":"Exp Cell Res"},{"key":"8350_CR55","doi-asserted-by":"crossref","first-page":"735","DOI":"10.1016\/S0960-9822(02)00809-6","volume":"12","author":"M Lagos-Quintana","year":"2002","unstructured":"Lagos-Quintana M, Rauhut R, Yalcin A, Meyer J, Lendeckel W, Tuschl T (2002) Identification of tissue-specific microRNAs from mouse. Curr Biol 12:735\u2013739. doi: 10.1016\/S0960-9822(02)00809-6","journal-title":"Curr Biol"},{"key":"8350_CR56","doi-asserted-by":"crossref","first-page":"1274","DOI":"10.1261\/rna.5980303","volume":"9","author":"AM Krichevsky","year":"2003","unstructured":"Krichevsky AM, King KS, Donahue CP, Khrapko K, Kosik KS (2003) A microRNA array reveals extensive regulation of microRNAs during brain development. RNA 9:1274\u20131281","journal-title":"RNA"},{"key":"8350_CR57","doi-asserted-by":"crossref","first-page":"R13","DOI":"10.1186\/gb-2004-5-3-r13","volume":"5","author":"LF Sempere","year":"2004","unstructured":"Sempere LF, Freemantle S, Pitha-Rowe I, Moss E, Dmitrovsky E, Ambros V (2004) Expression profiling of mammalian microRNAs uncovers a subset of brain-expressed microRNAs with possible roles in murine and human neuronal differentiation. Genome Biol 5:R13. doi: 10.1186\/gb-2004-5-3-r13","journal-title":"Genome Biol"},{"key":"8350_CR58","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1186\/1749-8104-5-25","volume":"5","author":"FB Gao","year":"2010","unstructured":"Gao FB (2010) Context-dependent functions of specific microRNAs in neuronal development. Neural Dev 5:25. doi: 10.1186\/1749-8104-5-25","journal-title":"Neural Dev"},{"key":"8350_CR59","doi-asserted-by":"crossref","first-page":"12135","DOI":"10.1073\/pnas.0505479102","volume":"102","author":"EP Murchison","year":"2005","unstructured":"Murchison EP, Partridge JF, Tam OH, Cheloufi S, Hannon GJ (2005) Characterization of Dicer-deficient murine embryonic stem cells. Proc Natl Acad Sci U S A 102:12135\u201312140. doi: 10.1073\/pnas.0505479102","journal-title":"Proc Natl Acad Sci U S A"},{"key":"8350_CR60","doi-asserted-by":"crossref","first-page":"2800","DOI":"10.1002\/dvdy.22109","volume":"238","author":"Y Kawase-Koga","year":"2009","unstructured":"Kawase-Koga Y, Otaegi G, Sun T (2009) Different timings of Dicer deletion affect neurogenesis and gliogenesis in the developing mouse central nervous system. Dev Dyn 238:2800\u20132812. doi: 10.1002\/dvdy.22109","journal-title":"Dev Dyn"},{"key":"8350_CR61","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1007\/s00418-011-0853-8","volume":"136","author":"T Wakabayashi","year":"2011","unstructured":"Wakabayashi T, Mori T, Hirahara Y, Koike T, Kubota Y, Takamori Y, Yamada H (2011) Nuclear lamins are differentially expressed in retinal neurons of the adult rat retina. Histochem Cell Biol 136:427\u2013436. doi: 10.1007\/s00418-011-0853-8","journal-title":"Histochem Cell Biol"},{"key":"8350_CR62","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.celrep.2012.05.015","volume":"1","author":"X Nissan","year":"2012","unstructured":"Nissan X, Biondel S, Navarro C, Maury Y, Denis C, Girard M, Martinat C, De Sandre-Giovannoli A, Levy N, Peschanski M (2012) Unique preservation of neural cells in Hutchinson\u2013Gilford progeria syndrome Is due to the expression of the neural-specific miR-9 microRNA. Cell Reports 1:1\u20139. doi: 10.1016\/j.celrep. 2012.05.015","journal-title":"Cell Reports"},{"key":"8350_CR63","doi-asserted-by":"crossref","first-page":"3407","DOI":"10.1523\/JNEUROSCI.5085-10.2011","volume":"31","author":"M Shibata","year":"2011","unstructured":"Shibata M, Nakao H, Kiyonari H, Abe T, Aizawa S (2011) MicroRNA-9 regulates neurogenesis in mouse telencephalon by targeting multiple transcription factors. J Neurosci 31:3407\u20133422. doi: 10.1523\/JNEUROSCI.5085-10.2011","journal-title":"J Neurosci"},{"key":"8350_CR64","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1016\/j.stem.2010.12.002","volume":"8","author":"J Zhang","year":"2011","unstructured":"Zhang J, Lian Q, Zhu G, Zhou F, Sui L, Tan C, Mutalif RA, Navasankari R, Zhang Y, Tse HF, Stewart CL, Colman A (2011) A human iPSC model of Hutchinson Gilford Progeria reveals vascular smooth muscle and mesenchymal stem cell defects. Cell Stem Cell 8:31\u201345. doi: 10.1016\/j.stem.2010.12.002","journal-title":"Cell Stem Cell"},{"key":"8350_CR65","doi-asserted-by":"crossref","first-page":"2144","DOI":"10.1016\/j.yexcr.2007.03.026","volume":"313","author":"CL Stewart","year":"2007","unstructured":"Stewart CL, Kozlov S, Fong LG, Young SG (2007) Mouse models of the laminopathies. Exp Cell Res 313:2144\u20132156. doi: 10.1016\/j.yexcr.2007.03.026","journal-title":"Exp Cell Res"},{"key":"8350_CR66","doi-asserted-by":"crossref","first-page":"1114","DOI":"10.1038\/ng1872","volume":"38","author":"QS Padiath","year":"2006","unstructured":"Padiath QS, Saigoh K, Schiffmann R, Asahara H, Yamada T, Koeppen A, Hogan K, Ptacek LJ, Fu YH (2006) Lamin B1 duplications cause autosomal dominant leukodystrophy. Nat Genet 38:1114\u20131123. doi: 10.1038\/ng1872","journal-title":"Nat Genet"},{"key":"8350_CR67","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1136\/jnnp.2008.147330","volume":"80","author":"A Brussino","year":"2009","unstructured":"Brussino A, Vaula G, Cagnoli C, Mauro A, Pradotto L, Daniele D, Di Gregorio E, Barberis M, Arduino C, Squadrone S, Abete MC, Migone N, Calabrese O, Brusco A (2009) A novel family with Lamin B1 duplication associated with adult-onset leucoencephalopathy. J Neurol Neurosurg Psychiatry 80:237\u2013240. doi: 10.1136\/jnnp. 2008.147330","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"8350_CR68","doi-asserted-by":"crossref","first-page":"1496","DOI":"10.1001\/archneur.65.11.1496","volume":"65","author":"IA Meijer","year":"2008","unstructured":"Meijer IA, Simoes-Lopes AA, Laurent S, Katz T, St-Onge J, Verlaan DJ, Dupre N, Thibault M, Mathurin J, Bouchard JP, Rouleau GA (2008) A novel duplication confirms the involvement of 5q23.2 in autosomal dominant leukodystrophy. Arch Neurol 65:1496\u20131501. doi: 10.1001\/archneur.65.11.1496","journal-title":"Arch Neurol"},{"key":"8350_CR69","doi-asserted-by":"crossref","first-page":"948","DOI":"10.1056\/NEJM198410113111504","volume":"311","author":"R Eldridge","year":"1984","unstructured":"Eldridge R, Anayiotos CP, Schlesinger S, Cowen D, Bever C, Patronas N, McFarland H (1984) Hereditary adult-onset leukodystrophy simulating chronic progressive multiple sclerosis. N Engl J Med 311:948\u2013953","journal-title":"N Engl J Med"},{"key":"8350_CR70","doi-asserted-by":"crossref","first-page":"757","DOI":"10.1001\/archneur.1994.00540200033013","volume":"51","author":"JD Schwankhaus","year":"1994","unstructured":"Schwankhaus JD, Katz DA, Eldridge R, Schlesinger S, McFarland H (1994) Clinical and pathological features of an autosomal dominant, adult-onset leukodystrophy simulating chronic progressive multiple sclerosis. Arch Neurol 51:757\u2013766","journal-title":"Arch Neurol"},{"key":"8350_CR71","doi-asserted-by":"crossref","first-page":"423","DOI":"10.1007\/s002340050437","volume":"39","author":"M Bergui","year":"1997","unstructured":"Bergui M, Bradac GB, Leombruni S, Vaula G, Quattrocolo G (1997) MRI and CT in an autosomal-dominant, adult-onset leukodystrophy. Neuroradiology 39:423\u2013426","journal-title":"Neuroradiology"},{"key":"8350_CR72","doi-asserted-by":"crossref","first-page":"787","DOI":"10.1093\/hmg\/9.5.787","volume":"9","author":"CM Coffeen","year":"2000","unstructured":"Coffeen CM, McKenna CE, Koeppen AH, Plaster NM, Maragakis N, Mihalopoulos J, Schwankhaus JD, Flanigan KM, Gregg RG, Ptacek LJ, Fu YH (2000) Genetic localization of an autosomal dominant leukodystrophy mimicking chronic progressive multiple sclerosis to chromosome 5q31. Hum Mol Genet 9:787\u2013793. doi: 10.1093\/hmg\/9.5.787","journal-title":"Hum Mol Genet"},{"key":"8350_CR73","first-page":"904","volume":"27","author":"A Melberg","year":"2006","unstructured":"Melberg A, Hallberg L, Kalimo H, Raininko R (2006) MR characteristics and neuropathology in adult-onset autosomal dominant leukodystrophy with autonomic symptoms. AJNR Am J Neuroradiol 27:904\u2013911","journal-title":"AJNR Am J Neuroradiol"},{"key":"8350_CR74","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1007\/s10048-010-0269-y","volume":"12","author":"J Schuster","year":"2011","unstructured":"Schuster J, Sundblom J, Thuresson AC, Hassin-Baer S, Klopstock T, Dichgans M, Cohen OS, Raininko R, Melberg A, Dahl N (2011) Genomic duplications mediate overexpression of lamin B1 in adult-onset autosomal dominant leukodystrophy (ADLD) with autonomic symptoms. Neurogenetics 12:65\u201372. doi: 10.1007\/s10048-010-0269-y","journal-title":"Neurogenetics"},{"key":"8350_CR75","doi-asserted-by":"crossref","first-page":"541","DOI":"10.1111\/j.1468-1331.2009.02844.x","volume":"17","author":"A Brussino","year":"2010","unstructured":"Brussino A, Vaula G, Cagnoli C, Panza E, Seri M, Di Gregorio E, Scappaticci S, Camanini S, Daniele D, Bradac GB, Pinessi L, Cavalieri S, Grosso E, Migone N, Brusco A (2010) A family with autosomal dominant leukodystrophy linked to 5q23.2\u2013q23.3 without lamin B1 mutations. Eur J Neurol 17:541\u2013549. doi: 10.1111\/j.1468-1331.2009.02844.x","journal-title":"Eur J Neurol"},{"key":"8350_CR76","doi-asserted-by":"crossref","first-page":"178","DOI":"10.1242\/dmm.001065","volume":"2","author":"ST Lin","year":"2009","unstructured":"Lin ST, Fu YH (2009) miR-23 regulation of lamin B1 is crucial for oligodendrocyte development and myelination. Dis Model Mech 2:178\u2013188. doi: 10.1242\/dmm.001065","journal-title":"Dis Model Mech"},{"key":"8350_CR77","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1016\/j.euroneuro.2010.02.005","volume":"20","author":"SI Deutsch","year":"2010","unstructured":"Deutsch SI, Burket JA, Katz E (2010) Does subtle disturbance of neuronal migration contribute to schizophrenia and other neurodevelopmental disorders? Potential genetic mechanisms with possible treatment implications. Eur Neuropsychopharmacol 20:281\u2013287. doi: 10.1016\/j.euroneuro.2010.02.005","journal-title":"Eur Neuropsychopharmacol"},{"key":"8350_CR78","doi-asserted-by":"crossref","first-page":"755","DOI":"10.1007\/s00401-010-0655-4","volume":"119","author":"J Wegiel","year":"2010","unstructured":"Wegiel J, Kuchna I, Nowicki K, Imaki H, Marchi E, Ma SY, Chauhan A, Chauhan V, Bobrowicz TW, de Leon M, Louis LA, Cohen IL, London E, Brown WT, Wisniewski T (2010) The neuropathology of autism: defects of neurogenesis and neuronal migration, and dysplastic changes. Acta Neuropathol 119:755\u2013770. doi: 10.1007\/s00401-010-0655-4","journal-title":"Acta Neuropathol"}],"container-title":["Molecular Neurobiology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s12035-012-8350-1.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s12035-012-8350-1\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s12035-012-8350-1","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,1,30]],"date-time":"2022-01-30T04:54:20Z","timestamp":1643518460000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s12035-012-8350-1"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,10,14]]},"references-count":78,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2013,2]]}},"alternative-id":["8350"],"URL":"https:\/\/doi.org\/10.1007\/s12035-012-8350-1","relation":{"has-review":[{"id-type":"doi","id":"10.3410\/f.717960570.793523833","asserted-by":"object"}]},"ISSN":["0893-7648","1559-1182"],"issn-type":[{"value":"0893-7648","type":"print"},{"value":"1559-1182","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,10,14]]}}}