{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T20:08:51Z","timestamp":1791317331345,"version":"4.3.1"},"reference-count":66,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2014,8,17]],"date-time":"2014-08-17T00:00:00Z","timestamp":1408233600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Mol Neurobiol"],"published-print":{"date-parts":[[2015,8]]},"DOI":"10.1007\/s12035-014-8852-0","type":"journal-article","created":{"date-parts":[[2014,8,16]],"date-time":"2014-08-16T00:05:01Z","timestamp":1408147501000},"page":"142-161","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":17,"title":["AP-1\/\u03c31B-Dependent SV Protein Recycling Is Regulated in Early Endosomes and Is Coupled to AP-2 Endocytosis"],"prefix":"10.1007","volume":"52","author":[{"given":"Manuel","family":"Kratzke","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ermes","family":"Candiello","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bernhard","family":"Schmidt","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Olaf","family":"Jahn","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter","family":"Schu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2014,8,17]]},"reference":[{"issue":"4","key":"8852_CR1","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1016\/j.tcb.2004.02.002","volume":"14","author":"MS Robinson","year":"2004","unstructured":"Robinson MS (2004) Adaptable adaptors for coated vesicles. Trends Cell Biol 14(4):167\u2013174","journal-title":"Trends Cell Biol"},{"issue":"10","key":"8852_CR2","doi-asserted-by":"crossref","first-page":"2907","DOI":"10.1091\/mbc.12.10.2907","volume":"12","author":"M Boehm","year":"2001","unstructured":"Boehm M, Bonifacino JS (2001) Adaptins: the final recount. Mol Biol Cell 12(10):2907\u20132920","journal-title":"Mol Biol Cell"},{"issue":"8","key":"8852_CR3","doi-asserted-by":"publisher","first-page":"1318","DOI":"10.1038\/emboj.2010.15","volume":"29","author":"N Glyvuk","year":"2010","unstructured":"Glyvuk N, Tsytsyura Y, Geumann C, D\u2019Hooge R, Huve J, Kratzke M, Baltes J, Boning D, Klingauf J, Schu P (2010) AP-1\/\u03c31B-adaptin mediates endosomal synaptic vesicle recycling, learning and memory. EMBO J 29(8):1318\u20131330. doi: 10.1038\/emboj.2010.15","journal-title":"EMBO J"},{"key":"8852_CR4","doi-asserted-by":"crossref","first-page":"2193","DOI":"10.1093\/emboj\/19.10.2193","volume":"19","author":"C Meyer","year":"2000","unstructured":"Meyer C, Zizioli D, Lausmann S, Eskelinen EL, Hamann J, Saftig P, von Figura K, Schu P (2000) \u03bc1A adaptin-deficient mice: lethality, loss of AP-1 binding and rerouting of mannose 6-phosphate receptors. EMBO J 19:2193\u20132203","journal-title":"EMBO J"},{"issue":"6","key":"8852_CR5","doi-asserted-by":"crossref","first-page":"1119","DOI":"10.1086\/510137","volume":"79","author":"PS Tarpey","year":"2006","unstructured":"Tarpey PS, Stevens C, Teague J, Edkins S, O'Meara S, Avis T, Barthorpe S, Buck G, Butler A, Cole J, Dicks E, Gray K, Halliday K, Harrison R, Hills K, Hinton J, Jones D, Menzies A, Mironenko T, Perry J, Raine K, Richardson D, Shepherd R, Small A, Tofts C, Varian J, West S, Widaa S, Yates A, Catford R, Butler J, Mallya U, Moon J, Luo Y, Dorkins H, Thompson D, Easton DF, Wooster R, Bobrow M, Carpenter N, Simensen RJ, Schwartz CE, Stevenson RE, Turner G, Partington M, Gecz J, Stratton MR, Futreal PA, Raymond FL (2006) Mutations in the gene encoding the \u03c32 subunit of the adaptor protein 1 complex, AP1S2, cause X-linked mental retardation. Am J Hum Genet 79(6):1119\u20131124","journal-title":"Am J Hum Genet"},{"issue":"6","key":"8852_CR6","doi-asserted-by":"publisher","first-page":"333","DOI":"10.1042\/BC20070007","volume":"99","author":"MR Schmidt","year":"2007","unstructured":"Schmidt MR, Haucke V (2007) Recycling endosomes in neuronal membrane traffic. Biol Cell 99(6):333\u2013342. doi: 10.1042\/BC20070007","journal-title":"Biol Cell"},{"issue":"9","key":"8852_CR7","doi-asserted-by":"crossref","first-page":"1163","DOI":"10.1111\/j.1600-0854.2006.00466.x","volume":"7","author":"SO Rizzoli","year":"2006","unstructured":"Rizzoli SO, Bethani I, Zwilling D, Wenzel D, Siddiqui TJ, Brandhorst D, Jahn R (2006) Evidence for early endosome-like fusion of recently endocytosed synaptic vesicles. Traffic 7(9):1163\u20131176","journal-title":"Traffic"},{"issue":"4","key":"8852_CR8","doi-asserted-by":"crossref","first-page":"831","DOI":"10.1016\/j.cell.2006.10.030","volume":"127","author":"S Takamori","year":"2006","unstructured":"Takamori S, Holt M, Stenius K, Lemke EA, Gronborg M, Riedel D, Urlaub H, Schenck S, Brugger B, Ringler P, Muller SA, Rammner B, Grater F, Hub JS, De Groot BL, Mieskes G, Moriyama Y, Klingauf J, Grubmuller H, Heuser J, Wieland F, Jahn R (2006) Molecular anatomy of a trafficking organelle. Cell 127(4):831\u2013846","journal-title":"Cell"},{"issue":"22","key":"8852_CR9","doi-asserted-by":"publisher","first-page":"4025","DOI":"10.1002\/pmic.201000253","volume":"10","author":"PS McPherson","year":"2010","unstructured":"McPherson PS (2010) Proteomic analysis of clathrin-coated vesicles. Proteomics 10(22):4025\u20134039. doi: 10.1002\/pmic.201000253","journal-title":"Proteomics"},{"issue":"4","key":"8852_CR10","doi-asserted-by":"crossref","first-page":"571","DOI":"10.1083\/jcb.200607164","volume":"175","author":"GH Borner","year":"2006","unstructured":"Borner GH, Harbour M, Hester S, Lilley KS, Robinson MS (2006) Comparative proteomics of clathrin-coated vesicles. J Cell Biol 175(4):571\u2013578","journal-title":"J Cell Biol"},{"issue":"9","key":"8852_CR11","doi-asserted-by":"publisher","first-page":"1417","DOI":"10.1002\/pmic.201200366","volume":"13","author":"C Schmidt","year":"2013","unstructured":"Schmidt C, Hesse D, Raabe M, Urlaub H, Jahn O (2013) An automated in-gel digestion\/iTRAQ-labeling workflow for robust quantification of gel-separated proteins. Proteomics 13(9):1417\u20131422. doi: 10.1002\/pmic.201200366","journal-title":"Proteomics"},{"issue":"5","key":"8852_CR12","doi-asserted-by":"crossref","first-page":"1374","DOI":"10.1083\/jcb.96.5.1374","volume":"96","author":"WB Huttner","year":"1983","unstructured":"Huttner WB, Schiebler W, Greengard P, De Camilli P (1983) Synapsin I (protein I), a nerve terminal-specific phosphoprotein. III. Its association with synaptic vesicles studied in a highly purified synaptic vesicle preparation. J Cell Biol 96(5):1374\u20131388","journal-title":"J Cell Biol"},{"issue":"2","key":"8852_CR13","doi-asserted-by":"publisher","first-page":"107","DOI":"10.1038\/35052055","volume":"2","author":"M Zerial","year":"2001","unstructured":"Zerial M, McBride H (2001) Rab proteins as membrane organizers. Nat Rev Mol Cell Biol 2(2):107\u2013117. doi: 10.1038\/35052055","journal-title":"Nat Rev Mol Cell Biol"},{"issue":"14","key":"8852_CR14","doi-asserted-by":"publisher","first-page":"9835","DOI":"10.1074\/jbc.M112.427591","volume":"288","author":"Y Mori","year":"2013","unstructured":"Mori Y, Matsui T, Fukuda M (2013) Rabex-5 protein regulates dendritic localization of small GTPase Rab17 and neurite morphogenesis in hippocampal neurons. J Biol Chem 288(14):9835\u20139847. doi: 10.1074\/jbc.M112.427591","journal-title":"J Biol Chem"},{"issue":"6692","key":"8852_CR15","doi-asserted-by":"publisher","first-page":"494","DOI":"10.1038\/28879","volume":"394","author":"A Simonsen","year":"1998","unstructured":"Simonsen A, Lippe R, Christoforidis S, Gaullier JM, Brech A, Callaghan J, Toh BH, Murphy C, Zerial M, Stenmark H (1998) EEA1 links PI(3)K function to Rab5 regulation of endosome fusion. Nature 394(6692):494\u2013498. doi: 10.1038\/28879","journal-title":"Nature"},{"issue":"8","key":"8852_CR16","doi-asserted-by":"crossref","first-page":"2657","DOI":"10.1091\/mbc.11.8.2657","volume":"11","author":"JM Wilson","year":"2000","unstructured":"Wilson JM, de Hoop M, Zorzi N, Toh BH, Dotti CG, Parton RG (2000) EEA1, a tethering protein of the early sorting endosome, shows a polarized distribution in hippocampal neurons, epithelial cells, and fibroblasts. Mol Biol Cell 11(8):2657\u20132671","journal-title":"Mol Biol Cell"},{"issue":"6","key":"8852_CR17","doi-asserted-by":"crossref","first-page":"2131","DOI":"10.1091\/mbc.11.6.2131","volume":"11","author":"SM Leung","year":"2000","unstructured":"Leung SM, Ruiz WG, Apodaca G (2000) Sorting of membrane and fluid at the apical pole of polarized Madin-Darby canine kidney cells. Mol Biol Cell 11(6):2131\u20132150","journal-title":"Mol Biol Cell"},{"issue":"4","key":"8852_CR18","doi-asserted-by":"publisher","first-page":"811","DOI":"10.1016\/j.devcel.2012.02.004","volume":"22","author":"D Gravotta","year":"2012","unstructured":"Gravotta D, Carvajal-Gonzalez JM, Mattera R, Deborde S, Banfelder JR, Bonifacino JS, Rodriguez-Boulan E (2012) The clathrin adaptor AP-1A mediates basolateral polarity. Dev Cell 22(4):811\u2013823. doi: 10.1016\/j.devcel.2012.02.004","journal-title":"Dev Cell"},{"issue":"3","key":"8852_CR19","doi-asserted-by":"publisher","first-page":"633","DOI":"10.1016\/j.mcn.2011.01.003","volume":"46","author":"D Majumdar","year":"2011","unstructured":"Majumdar D, Nebhan CA, Hu L, Anderson B, Webb DJ (2011) An APPL1\/Akt signaling complex regulates dendritic spine and synapse formation in hippocampal neurons. Mol Cell Neurosci 46(3):633\u2013644. doi: 10.1016\/j.mcn.2011.01.003","journal-title":"Mol Cell Neurosci"},{"key":"8852_CR20","doi-asserted-by":"publisher","first-page":"8","DOI":"10.1152\/physiol.00035.2008","volume":"24","author":"HJ McCrea","year":"2009","unstructured":"McCrea HJ, De Camilli P (2009) Mutations in phosphoinositide metabolizing enzymes and human disease. Physiology (Bethesda) 24:8\u201316. doi: 10.1152\/physiol.00035.2008","journal-title":"Physiology (Bethesda)"},{"issue":"6","key":"8852_CR21","doi-asserted-by":"publisher","first-page":"1097","DOI":"10.1016\/j.neuron.2013.01.025","volume":"77","author":"TM Khuong","year":"2013","unstructured":"Khuong TM, Habets RL, Kuenen S, Witkowska A, Kasprowicz J, Swerts J, Jahn R, van den Bogaart G, Verstreken P (2013) Synaptic PI(3,4,5)P3 is required for syntaxin1A clustering and neurotransmitter release. Neuron 77(6):1097\u20131108. doi: 10.1016\/j.neuron.2013.01.025","journal-title":"Neuron"},{"issue":"5","key":"8852_CR22","doi-asserted-by":"publisher","first-page":"461","DOI":"10.1038\/ncb2721","volume":"15","author":"F Steinberg","year":"2013","unstructured":"Steinberg F, Gallon M, Winfield M, Thomas EC, Bell AJ, Heesom KJ, Tavare JM, Cullen PJ (2013) A global analysis of SNX27-retromer assembly and cargo specificity reveals a function in glucose and metal ion transport. Nat Cell Biol 15(5):461\u2013471. doi: 10.1038\/ncb2721","journal-title":"Nat Cell Biol"},{"issue":"21","key":"8852_CR23","doi-asserted-by":"publisher","first-page":"3290","DOI":"10.1038\/emboj.2009.272","volume":"28","author":"A Shi","year":"2009","unstructured":"Shi A, Sun L, Banerjee R, Tobin M, Zhang Y, Grant BD (2009) Regulation of endosomal clathrin and retromer-mediated endosome to Golgi retrograde transport by the J-domain protein RME-8. EMBO J 28(21):3290\u20133302. doi: 10.1038\/emboj.2009.272","journal-title":"EMBO J"},{"issue":"48","key":"8852_CR24","doi-asserted-by":"publisher","first-page":"40135","DOI":"10.1074\/jbc.M505036200","volume":"280","author":"M Girard","year":"2005","unstructured":"Girard M, Poupon V, Blondeau F, McPherson PS (2005) The DnaJ-domain protein RME-8 functions in endosomal trafficking. J Biol Chem 280(48):40135\u201340143. doi: 10.1074\/jbc.M505036200","journal-title":"J Biol Chem"},{"issue":"23","key":"8852_CR25","doi-asserted-by":"publisher","first-page":"4611","DOI":"10.1091\/mbc.E12-05-0343","volume":"23","author":"BT Lobingier","year":"2012","unstructured":"Lobingier BT, Merz AJ (2012) Sec1\/Munc18 protein Vps33 binds to SNARE domains and the quaternary SNARE complex. Mol Biol Cell 23(23):4611\u20134622. doi: 10.1091\/mbc.E12-05-0343","journal-title":"Mol Biol Cell"},{"issue":"7","key":"8852_CR26","doi-asserted-by":"publisher","first-page":"1218","DOI":"10.1111\/j.1600-0854.2008.00752.x","volume":"9","author":"KN Kitt","year":"2008","unstructured":"Kitt KN, Hernandez-Deviez D, Ballantyne SD, Spiliotis ET, Casanova JE, Wilson JM (2008) Rab14 regulates apical targeting in polarized epithelial cells. Traffic 9(7):1218\u20131231. doi: 10.1111\/j.1600-0854.2008.00752.x","journal-title":"Traffic"},{"issue":"9","key":"8852_CR27","doi-asserted-by":"publisher","first-page":"1211","DOI":"10.1111\/j.1600-0854.2011.01220.x","volume":"12","author":"L Malerod","year":"2011","unstructured":"Malerod L, Pedersen NM, Sem Wegner CE, Lobert VH, Leithe E, Brech A, Rivedal E, Liestol K, Stenmark H (2011) Cargo-dependent degradation of ESCRT-I as a feedback mechanism to modulate endosomal sorting. Traffic 12(9):1211\u20131226. doi: 10.1111\/j.1600-0854.2011.01220.x","journal-title":"Traffic"},{"issue":"10","key":"8852_CR28","doi-asserted-by":"publisher","first-page":"1285","DOI":"10.1038\/nn.2898","volume":"14","author":"GY Goh","year":"2011","unstructured":"Goh GY, Huang H, Ullman J, Borre L, Hnasko TS, Trussell LO, Edwards RH (2011) Presynaptic regulation of quantal size: K+\/H\u2009+\u2009exchange stimulates vesicular glutamate transport. Nat Neurosci 14(10):1285\u20131292. doi: 10.1038\/nn.2898","journal-title":"Nat Neurosci"},{"issue":"3","key":"8852_CR29","doi-asserted-by":"publisher","first-page":"266","DOI":"10.1002\/cne.20008","volume":"470","author":"R Belizaire","year":"2004","unstructured":"Belizaire R, Komanduri C, Wooten K, Chen M, Thaller C, Janz R (2004) Characterization of synaptogyrin 3 as a new synaptic vesicle protein. J Comp Neurol 470(3):266\u2013281. doi: 10.1002\/cne.20008","journal-title":"J Comp Neurol"},{"issue":"2","key":"8852_CR30","doi-asserted-by":"publisher","first-page":"139","DOI":"10.1002\/cne.10371","volume":"452","author":"I Singec","year":"2002","unstructured":"Singec I, Knoth R, Ditter M, Hagemeyer CE, Rosenbrock H, Frotscher M, Volk B (2002) Synaptic vesicle protein synaptoporin is differently expressed by subpopulations of mouse hippocampal neurons. J Comp Neurol 452(2):139\u2013153. doi: 10.1002\/cne.10371","journal-title":"J Comp Neurol"},{"issue":"21","key":"8852_CR31","doi-asserted-by":"crossref","first-page":"7941","DOI":"10.1523\/JNEUROSCI.20-21-07941.2000","volume":"20","author":"R Fernandez-Chacon","year":"2000","unstructured":"Fernandez-Chacon R, Sudhof TC (2000) Novel SCAMPs lacking NPF repeats: ubiquitous and synaptic vesicle-specific forms implicate SCAMPs in multiple membrane-trafficking functions. J Neurosci 20(21):7941\u20137950","journal-title":"J Neurosci"},{"issue":"1","key":"8852_CR32","doi-asserted-by":"publisher","first-page":"99","DOI":"10.1016\/j.neuron.2012.10.033","volume":"77","author":"KJ Lee","year":"2013","unstructured":"Lee KJ, Queenan BN, Rozeboom AM, Bellmore R, Lim ST, Vicini S, Pak DT (2013) Mossy fiber-CA3 synapses mediate homeostatic plasticity in mature hippocampal neurons. Neuron 77(1):99\u2013114. doi: 10.1016\/j.neuron.2012.10.033","journal-title":"Neuron"},{"issue":"3","key":"8852_CR33","doi-asserted-by":"publisher","first-page":"1233","DOI":"10.1016\/j.neuroscience.2006.05.010","volume":"141","author":"T Sun","year":"2006","unstructured":"Sun T, Xiao HS, Zhou PB, Lu YJ, Bao L, Zhang X (2006) Differential expression of synaptoporin and synaptophysin in primary sensory neurons and up-regulation of synaptoporin after peripheral nerve injury. Neuroscience 141(3):1233\u20131245. doi: 10.1016\/j.neuroscience.2006.05.010","journal-title":"Neuroscience"},{"issue":"6","key":"8852_CR34","doi-asserted-by":"crossref","first-page":"1922","DOI":"10.1523\/JNEUROSCI.19-06-01922.1999","volume":"19","author":"A Becher","year":"1999","unstructured":"Becher A, Drenckhahn A, Pahner I, Margittai M, Jahn R, Ahnert-Hilger G (1999) The synaptophysin-synaptobrevin complex: a hallmark of synaptic vesicle maturation. J Neurosci 19(6):1922\u20131931","journal-title":"J Neurosci"},{"issue":"4","key":"8852_CR35","doi-asserted-by":"publisher","first-page":"755","DOI":"10.1016\/j.cell.2012.12.042","volume":"152","author":"X Ren","year":"2013","unstructured":"Ren X, Farias GG, Canagarajah BJ, Bonifacino JS, Hurley JH (2013) Structural basis for recruitment and activation of the AP-1 clathrin adaptor complex by Arf1. Cell 152(4):755\u2013767. doi: 10.1016\/j.cell.2012.12.042","journal-title":"Cell"},{"issue":"21","key":"8852_CR36","doi-asserted-by":"publisher","first-page":"2185","DOI":"10.1016\/j.cub.2013.09.017","volume":"23","author":"M Wieffer","year":"2013","unstructured":"Wieffer M, Uhalte EC, Posor Y, Otten C, Branz K, Sch\u00fctz I, M\u00f6ssinger J, Schu P, Abdelilah-Seyfried S, Krau\u00df M, Haucke V (2013) PI4K2\u03b2\/AP-1-based TGN-endosomal sorting regulates Wnt signaling. Curr Biol 23(21):2185\u20132190. doi: 10.1016\/j.cub.2013.09.017","journal-title":"Curr Biol"},{"issue":"5","key":"8852_CR37","doi-asserted-by":"publisher","first-page":"559","DOI":"10.1038\/ncb2221","volume":"13","author":"M Bai","year":"2011","unstructured":"Bai M, Gad H, Turacchio G, Cocucci E, Yang JS, Li J, Beznoussenko GV, Nie Z, Luo R, Fu L, Collawn JF, Kirchhausen T, Luini A, Hsu VW (2011) ARFGAP1 promotes AP-2-dependent endocytosis. Nat Cell Biol 13(5):559\u2013567. doi: 10.1038\/ncb2221","journal-title":"Nat Cell Biol"},{"key":"8852_CR38","doi-asserted-by":"publisher","first-page":"309","DOI":"10.1146\/annurev-cellbio-101011-155716","volume":"28","author":"FM Brodsky","year":"2012","unstructured":"Brodsky FM (2012) Diversity of clathrin function: new tricks for an old protein. Annu Rev Cell Dev Biol 28:309\u2013336. doi: 10.1146\/annurev-cellbio-101011-155716","journal-title":"Annu Rev Cell Dev Biol"},{"issue":"1","key":"8852_CR39","doi-asserted-by":"publisher","first-page":"137","DOI":"10.1016\/j.bpj.2013.05.012","volume":"105","author":"AC Kalli","year":"2013","unstructured":"Kalli AC, Morgan G, Sansom MS (2013) Interactions of the auxilin-1 PTEN-like domain with model membranes result in nanoclustering of phosphatidyl inositol phosphates. Biophys J 105(1):137\u2013145. doi: 10.1016\/j.bpj.2013.05.012","journal-title":"Biophys J"},{"issue":"6","key":"8852_CR40","doi-asserted-by":"crossref","first-page":"428","DOI":"10.1034\/j.1600-0854.2002.30606.x","volume":"3","author":"VI Korolchuk","year":"2002","unstructured":"Korolchuk VI, Banting G (2002) CK2 and GAK\/auxilin2 are major protein kinases in clathrin-coated vesicles. Traffic 3(6):428\u2013439","journal-title":"Traffic"},{"issue":"9","key":"8852_CR41","doi-asserted-by":"crossref","first-page":"4933","DOI":"10.1074\/jbc.270.9.4933","volume":"270","author":"LM Traub","year":"1995","unstructured":"Traub LM, Kornfeld S, Ungewickell E (1995) Different domains of the AP-1 adaptor complex are required for Golgi membrane binding and clathrin recruitment. J Biol Chem 270(9):4933\u20134942","journal-title":"J Biol Chem"},{"issue":"12","key":"8852_CR42","doi-asserted-by":"crossref","first-page":"885","DOI":"10.1046\/j.1398-9219.2003.0142.x","volume":"4","author":"SD Conner","year":"2003","unstructured":"Conner SD, Schroter T, Schmid SL (2003) AAK1-mediated micro2 phosphorylation is stimulated by assembled clathrin. Traffic 4(12):885\u2013890","journal-title":"Traffic"},{"issue":"5","key":"8852_CR43","doi-asserted-by":"publisher","first-page":"791","DOI":"10.1083\/jcb.200111068jcb.200111068","volume":"156","author":"D Ricotta","year":"2002","unstructured":"Ricotta D, Conner SD, Schmid SL, von Figura K, Honing S (2002) Phosphorylation of the AP2 mu subunit by AAK1 mediates high affinity binding to membrane protein sorting signals. J Cell Biol 156(5):791\u2013795. doi: 10.1083\/jcb.200111068jcb.200111068","journal-title":"J Cell Biol"},{"issue":"9","key":"8852_CR44","doi-asserted-by":"crossref","first-page":"5510","DOI":"10.1074\/jbc.M707166200","volume":"283","author":"D Ricotta","year":"2008","unstructured":"Ricotta D, Hansen J, Preiss C, Teichert D, Honing S (2008) Characterization of a protein phosphatase 2A holoenzyme that dephosphorylates the clathrin adaptors AP-1 and AP-2. J Biol Chem 283(9):5510\u20135517","journal-title":"J Biol Chem"},{"issue":"33","key":"8852_CR45","doi-asserted-by":"publisher","first-page":"13838","DOI":"10.1073\/pnas.0907008106","volume":"106","author":"H Chen","year":"2009","unstructured":"Chen H, Ko G, Zatti A, Di Giacomo G, Liu L, Raiteri E, Perucco E, Collesi C, Min W, Zeiss C, De Camilli P, Cremona O (2009) Embryonic arrest at midgestation and disruption of Notch signaling produced by the absence of both epsin 1 and epsin 2 in mice. Proc Natl Acad Sci U S A 106(33):13838\u201313843. doi: 10.1073\/pnas.0907008106","journal-title":"Proc Natl Acad Sci U S A"},{"issue":"10","key":"8852_CR46","doi-asserted-by":"publisher","first-page":"588","DOI":"10.1111\/boc.201200008","volume":"104","author":"T Maritzen","year":"2012","unstructured":"Maritzen T, Koo SJ, Haucke V (2012) Turning CALM into excitement: AP180 and CALM in endocytosis and disease. Biol Cell 104(10):588\u2013602. doi: 10.1111\/boc.201200008","journal-title":"Biol Cell"},{"issue":"1","key":"8852_CR47","doi-asserted-by":"publisher","first-page":"49","DOI":"10.1007\/s12017-012-8194-x","volume":"15","author":"RS Petralia","year":"2013","unstructured":"Petralia RS, Wang YX, Indig FE, Bushlin I, Wu F, Mattson MP, Yao PJ (2013) Reduction of AP180 and CALM produces defects in synaptic vesicle size and density. Neuromolecular Med 15(1):49\u201360. doi: 10.1007\/s12017-012-8194-x","journal-title":"Neuromolecular Med"},{"issue":"32","key":"8852_CR48","doi-asserted-by":"crossref","first-page":"22785","DOI":"10.1074\/jbc.274.32.22785","volume":"274","author":"W Hao","year":"1999","unstructured":"Hao W, Luo Z, Zheng L, Prasad K, Lafer EM (1999) AP180 and AP-2 interact directly in a complex that cooperatively assembles clathrin. J Biol Chem 274(32):22785\u201322794","journal-title":"J Biol Chem"},{"issue":"6","key":"8852_CR49","doi-asserted-by":"publisher","first-page":"E526","DOI":"10.1073\/pnas.1218432110","volume":"110","author":"NL Kononenko","year":"2013","unstructured":"Kononenko NL, Diril MK, Puchkov D, Kintscher M, Koo SJ, Pfuhl G, Winter Y, Wienisch M, Klingauf J, Breustedt J, Schmitz D, Maritzen T, Haucke V (2013) Compromised fidelity of endocytic synaptic vesicle protein sorting in the absence of stonin 2. Proc Natl Acad Sci U S A 110(6):E526\u2013E535. doi: 10.1073\/pnas.1218432110","journal-title":"Proc Natl Acad Sci U S A"},{"issue":"4","key":"8852_CR50","doi-asserted-by":"publisher","first-page":"393","DOI":"10.1016\/j.semcdb.2011.07.006","volume":"22","author":"O Shupliakov","year":"2011","unstructured":"Shupliakov O, Haucke V, Pechstein A (2011) How synapsin I may cluster synaptic vesicles. Semin Cell Dev Biol 22(4):393\u2013399. doi: 10.1016\/j.semcdb.2011.07.006","journal-title":"Semin Cell Dev Biol"},{"issue":"4","key":"8852_CR51","doi-asserted-by":"publisher","first-page":"1239","DOI":"10.1523\/JNEUROSCI.3553-05.2006","volume":"26","author":"OM Schluter","year":"2006","unstructured":"Schluter OM, Basu J, Sudhof TC, Rosenmund C (2006) Rab3 superprimes synaptic vesicles for release: implications for short-term synaptic plasticity. J Neurosci 26(4):1239\u20131246. doi: 10.1523\/JNEUROSCI.3553-05.2006","journal-title":"J Neurosci"},{"issue":"12","key":"8852_CR52","doi-asserted-by":"publisher","first-page":"9629","DOI":"10.1074\/jbc.C100730200","volume":"277","author":"F Nagano","year":"2002","unstructured":"Nagano F, Kawabe H, Nakanishi H, Shinohara M, Deguchi-Tawarada M, Takeuchi M, Sasaki T, Takai Y (2002) Rabconnectin-3, a novel protein that binds both GDP\/GTP exchange protein and GTPase-activating protein for Rab3 small G protein family. J Biol Chem 277(12):9629\u20139632. doi: 10.1074\/jbc.C100730200","journal-title":"J Biol Chem"},{"issue":"1","key":"8852_CR53","doi-asserted-by":"publisher","first-page":"13","DOI":"10.1016\/j.molbrainres.2005.05.004","volume":"139","author":"JH Han","year":"2005","unstructured":"Han JH, Lee C, Cheang Y, Kaang BK (2005) Suppression of long-term facilitation by Rab3-effector protein interaction. Brain Res 139(1):13\u201322. doi: 10.1016\/j.molbrainres.2005.05.004","journal-title":"Brain Res"},{"key":"8852_CR54","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1016\/S0076-6879(01)29068-5","volume":"329","author":"H Shirataki","year":"2001","unstructured":"Shirataki H, Sasaki T, Takai Y (2001) Rabphilin-3: a target molecule for Rab3 small G proteins. Methods Enzymol 329:75\u201382","journal-title":"Methods Enzymol"},{"issue":"6","key":"8852_CR55","doi-asserted-by":"publisher","first-page":"1171","DOI":"10.1016\/j.devcel.2011.10.007","volume":"21","author":"C Rosa-Ferreira","year":"2011","unstructured":"Rosa-Ferreira C, Munro S (2011) Arl8 and SKIP act together to link lysosomes to kinesin-1. Dev Cell 21(6):1171\u20131178. doi: 10.1016\/j.devcel.2011.10.007","journal-title":"Dev Cell"},{"key":"8852_CR56","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuron.2013.04.035","author":"YE Wu","year":"2013","unstructured":"Wu YE, Huo L, Maeder CI, Feng W, Shen K (2013) The balance between capture and dissociation of presynaptic proteins controls the spatial distribution of synapses. Neuron. doi: 10.1016\/j.neuron.2013.04.035","journal-title":"Neuron"},{"issue":"4","key":"8852_CR57","doi-asserted-by":"publisher","first-page":"791","DOI":"10.1016\/j.yexcr.2006.11.017","volume":"313","author":"Y Miyamoto","year":"2007","unstructured":"Miyamoto Y, Yamauchi J, Sanbe A, Tanoue A (2007) Dock6, a Dock-C subfamily guanine nucleotide exchanger, has the dual specificity for Rac1 and Cdc42 and regulates neurite outgrowth. Exp Cell Res 313(4):791\u2013804. doi: 10.1016\/j.yexcr.2006.11.017","journal-title":"Exp Cell Res"},{"issue":"265","key":"8852_CR58","doi-asserted-by":"publisher","first-page":"ra15","DOI":"10.1126\/scisignal.2003661","volume":"6","author":"Y Miyamoto","year":"2013","unstructured":"Miyamoto Y, Torii T, Yamamori N, Ogata T, Tanoue A, Yamauchi J (2013) Akt and PP2A reciprocally regulate the guanine nucleotide exchange factor Dock6 to control axon growth of sensory neurons. Sci Signal 6(265):ra15. doi: 10.1126\/scisignal.2003661","journal-title":"Sci Signal"},{"issue":"32","key":"8852_CR59","doi-asserted-by":"publisher","first-page":"10624","DOI":"10.1523\/JNEUROSCI.0402-10.2010","volume":"30","author":"C Gross","year":"2010","unstructured":"Gross C, Nakamoto M, Yao X, Chan CB, Yim SY, Ye K, Warren ST, Bassell GJ (2010) Excess phosphoinositide 3-kinase subunit synthesis and activity as a novel therapeutic target in fragile X syndrome. J Neurosci 30(32):10624\u201310638. doi: 10.1523\/JNEUROSCI.0402-10.2010","journal-title":"J Neurosci"},{"issue":"8","key":"8852_CR60","doi-asserted-by":"crossref","first-page":"585","DOI":"10.1016\/S0736-5748(02)00107-7","volume":"20","author":"MO Faison","year":"2002","unstructured":"Faison MO, Perozzi EF, Caran N, Stewart JK, Tombes RM (2002) Axonal localization of delta Ca2+\/calmodulin-dependent protein kinase II in developing P19 neurons. Int J Dev Neurosci 20(8):585\u2013592","journal-title":"Int J Dev Neurosci"},{"issue":"3","key":"8852_CR61","doi-asserted-by":"publisher","first-page":"223","DOI":"10.1002\/bies.10057","volume":"24","author":"C Rongo","year":"2002","unstructured":"Rongo C (2002) A fresh look at the role of CaMKII in hippocampal synaptic plasticity and memory. Bioessays 24(3):223\u2013233. doi: 10.1002\/bies.10057","journal-title":"Bioessays"},{"key":"8852_CR62","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.brainres.2011.06.036","volume":"1410","author":"T Umahara","year":"2011","unstructured":"Umahara T, Uchihara T, Nakamura A, Iwamoto T (2011) Differential expression of 14-3-3 protein isoforms in developing rat hippocampus, cortex, rostral migratory stream, olfactory bulb, and white matter. Brain Res 1410:1\u201311. doi: 10.1016\/j.brainres.2011.06.036","journal-title":"Brain Res"},{"key":"8852_CR63","doi-asserted-by":"publisher","DOI":"10.1111\/febs.12116","author":"C Raiborg","year":"2013","unstructured":"Raiborg C, Schink KO, Stenmark H (2013) Class III phosphatidylinositol 3-kinase and its catalytic product PtdIns3P in regulation of endocytic membrane traffic. FEBS J. doi: 10.1111\/febs.12116","journal-title":"FEBS J"},{"issue":"3","key":"8852_CR64","doi-asserted-by":"publisher","first-page":"313","DOI":"10.1016\/j.pneurobio.2011.01.003","volume":"93","author":"CS Bartheld Von","year":"2011","unstructured":"Von Bartheld CS, Altick AL (2011) Multivesicular bodies in neurons: distribution, protein content, and trafficking functions. Prog Neurobiol 93(3):313\u2013340. doi: 10.1016\/j.pneurobio.2011.01.003","journal-title":"Prog Neurobiol"},{"issue":"2","key":"8852_CR65","doi-asserted-by":"publisher","first-page":"233","DOI":"10.1016\/j.devcel.2005.12.011","volume":"10","author":"MK Diril","year":"2006","unstructured":"Diril MK, Wienisch M, Jung N, Klingauf J, Haucke V (2006) Stonin 2 is an AP-2-dependent endocytic sorting adaptor for synaptotagmin internalization and recycling. Dev Cell 10(2):233\u2013244. doi: 10.1016\/j.devcel.2005.12.011","journal-title":"Dev Cell"},{"issue":"7169","key":"8852_CR66","doi-asserted-by":"crossref","first-page":"570","DOI":"10.1038\/nature06353","volume":"450","author":"SE Miller","year":"2007","unstructured":"Miller SE, Collins BM, McCoy AJ, Robinson MS, Owen DJ (2007) A SNARE-adaptor interaction is a new mode of cargo recognition in clathrin-coated vesicles. Nature 450(7169):570\u2013574","journal-title":"Nature"}],"container-title":["Molecular Neurobiology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s12035-014-8852-0\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s12035-014-8852-0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s12035-014-8852-0","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s12035-014-8852-0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,8,14]],"date-time":"2019-08-14T02:13:49Z","timestamp":1565748829000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s12035-014-8852-0"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,8,17]]},"references-count":66,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2015,8]]}},"alternative-id":["8852"],"URL":"https:\/\/doi.org\/10.1007\/s12035-014-8852-0","relation":{},"ISSN":["0893-7648","1559-1182"],"issn-type":[{"value":"0893-7648","type":"print"},{"value":"1559-1182","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,8,17]]}}}