{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,6]],"date-time":"2026-02-06T04:05:49Z","timestamp":1770350749402,"version":"3.49.0"},"reference-count":73,"publisher":"Springer Science and Business Media LLC","issue":"6","license":[{"start":{"date-parts":[[2018,9,21]],"date-time":"2018-09-21T00:00:00Z","timestamp":1537488000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"funder":[{"name":"DFG","award":["GE2777\/2-1"],"award-info":[{"award-number":["GE2777\/2-1"]}]},{"name":"DFG","award":["Gu227\/16-1"],"award-info":[{"award-number":["Gu227\/16-1"]}]},{"name":"MERKUR","award":["An-2015-0044"],"award-info":[{"award-number":["An-2015-0044"]}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Mol Neurobiol"],"published-print":{"date-parts":[[2019,6]]},"DOI":"10.1007\/s12035-018-1351-y","type":"journal-article","created":{"date-parts":[[2018,9,20]],"date-time":"2018-09-20T21:55:13Z","timestamp":1537480513000},"page":"3999-4012","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":18,"title":["Myelin Water Fraction Imaging Reveals Hemispheric Asymmetries in Human White Matter That Are Associated with Genetic Variation in PLP1"],"prefix":"10.1007","volume":"56","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5882-3200","authenticated-orcid":false,"given":"Sebastian","family":"Ocklenburg","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Catrona","family":"Anderson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wanda M.","family":"Gerding","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christoph","family":"Fraenz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Caroline","family":"Schl\u00fcter","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Patrick","family":"Friedrich","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maximilian","family":"Raane","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Burkhard","family":"M\u00e4dler","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lara","family":"Schlaffke","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Larissa","family":"Arning","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J\u00f6rg T.","family":"Epplen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Onur","family":"G\u00fcnt\u00fcrk\u00fcn","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christian","family":"Beste","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Erhan","family":"Gen\u00e7","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2018,9,21]]},"reference":[{"key":"1351_CR1","volume-title":"The lateralized brain: the neuroscience and evolution of hemispheric asymmetries","author":"S Ocklenburg","year":"2018","unstructured":"Ocklenburg S, G\u00fcnt\u00fcrk\u00fcn O (2018) The lateralized brain: the neuroscience and evolution of hemispheric asymmetries. Academic Press, London"},{"key":"1351_CR2","doi-asserted-by":"publisher","DOI":"10.1093\/med\/9780199743261.001.0001","volume-title":"The behavioral neurology of white matter","author":"C Filley","year":"2012","unstructured":"Filley C (2012) The behavioral neurology of white matter, 2nd edn. Oxford University Press USA, Oxford","edition":"2"},{"issue":"10","key":"1351_CR3","doi-asserted-by":"publisher","first-page":"7908","DOI":"10.1007\/s12035-016-0285-5","volume":"54","author":"S Ocklenburg","year":"2017","unstructured":"Ocklenburg S, Gerding WM, Arning L, Gen\u00e7 E, Epplen JT, G\u00fcnt\u00fcrk\u00fcn O, Beste C (2017) Myelin genes and the corpus callosum: proteolipid protein 1 (PLP1) and contactin 1 (CNTN1) gene variation modulates interhemispheric integration. Mol Neurobiol 54(10):7908\u20137916. \n                    https:\/\/doi.org\/10.1007\/s12035-016-0285-5","journal-title":"Mol Neurobiol"},{"key":"1351_CR4","doi-asserted-by":"publisher","first-page":"310","DOI":"10.1016\/j.neuroimage.2017.09.048","volume":"163","author":"P Friedrich","year":"2017","unstructured":"Friedrich P, Ocklenburg S, Heins N, Schl\u00fcter C, Fraenz C, Beste C, G\u00fcnt\u00fcrk\u00fcn O, Gen\u00e7 E (2017) Callosal microstructure affects the timing of electrophysiological left-right differences. Neuroimage 163:310\u2013318. \n                    https:\/\/doi.org\/10.1016\/j.neuroimage.2017.09.048","journal-title":"Neuroimage"},{"issue":"6","key":"1351_CR5","doi-asserted-by":"publisher","first-page":"656","DOI":"10.1002\/jemt.1050","volume":"52","author":"EM Kr\u00e4mer","year":"2001","unstructured":"Kr\u00e4mer EM, Schardt A, Nave KA (2001) Membrane traffic in myelinating oligodendrocytes. Microsc Res Tech 52(6):656\u2013671. \n                    https:\/\/doi.org\/10.1002\/jemt.1050","journal-title":"Microsc Res Tech"},{"issue":"6","key":"1351_CR6","doi-asserted-by":"publisher","first-page":"799","DOI":"10.1083\/jcb.200602101","volume":"172","author":"T Boiko","year":"2006","unstructured":"Boiko T, Winckler B (2006) Myelin under construction\u2014teamwork required. J Cell Biol 172(6):799\u2013801. \n                    https:\/\/doi.org\/10.1083\/jcb.200602101","journal-title":"J Cell Biol"},{"issue":"3","key":"1351_CR7","doi-asserted-by":"publisher","first-page":"460","DOI":"10.1016\/j.nurt.2007.05.004","volume":"4","author":"C Laule","year":"2007","unstructured":"Laule C, Vavasour IM, Kolind SH, Li DKB, Traboulsee TL, Moore GRW, MacKay AL (2007) Magnetic resonance imaging of myelin. Neurotherapeutics 4(3):460\u2013484. \n                    https:\/\/doi.org\/10.1016\/j.nurt.2007.05.004","journal-title":"Neurotherapeutics"},{"issue":"5","key":"1351_CR8","doi-asserted-by":"publisher","first-page":"344","DOI":"10.1002\/(SICI)1097-0029(19980601)41:5<344:AID-JEMT2>3.0.CO;2-Q","volume":"41","author":"I Griffiths","year":"1998","unstructured":"Griffiths I, Klugmann M, Anderson T, Thomson C, Vouyiouklis D, Nave KA (1998) Current concepts of PLP and its role in the nervous system. Microsc Res Tech 41(5):344\u2013358. \n                    https:\/\/doi.org\/10.1002\/(SICI)1097-0029(19980601)41:5<344:AID-JEMT2>3.0.CO;2-Q","journal-title":"Microsc Res Tech"},{"issue":"2","key":"1351_CR9","doi-asserted-by":"publisher","first-page":"151","DOI":"10.1002\/1097-4547(20010115)63:2<151:AID-JNR1007>3.0.CO;2-Y","volume":"63","author":"DA Yool","year":"2001","unstructured":"Yool DA, Klugmann M, McLaughlin M, Vouyiouklis DA, Dimou L, Barrie JA, McCulloch MC, Nave KA et al (2001) Myelin proteolipid proteins promote the interaction of oligodendrocytes and axons. J Neurosci Res 63(2):151\u2013164. \n                    https:\/\/doi.org\/10.1002\/1097-4547(20010115)63:2<151:AID-JNR1007>3.0.CO;2-Y","journal-title":"J Neurosci Res"},{"issue":"3","key":"1351_CR10","doi-asserted-by":"publisher","first-page":"405","DOI":"10.1016\/j.mcn.2005.03.007","volume":"29","author":"E Chow","year":"2005","unstructured":"Chow E, Mottahedeh J, Prins M, Ridder W, Nusinowitz S, Bronstein JM (2005) Disrupted compaction of CNS myelin in an OSP\/Claudin-11 and PLP\/DM20 double knockout mouse. Mol Cell Neurosci 29(3):405\u2013413. \n                    https:\/\/doi.org\/10.1016\/j.mcn.2005.03.007","journal-title":"Mol Cell Neurosci"},{"issue":"1","key":"1351_CR11","doi-asserted-by":"publisher","first-page":"155","DOI":"10.1002\/glia.22922","volume":"64","author":"J Patzig","year":"2016","unstructured":"Patzig J, Kusch K, Fledrich R, Eichel MA, L\u00fcders KA, M\u00f6bius W, Sereda MW, Nave KA et al (2016) Proteolipid protein modulates preservation of peripheral axons and premature death when myelin protein zero is lacking. Glia 64(1):155\u2013174. \n                    https:\/\/doi.org\/10.1002\/glia.22922","journal-title":"Glia"},{"issue":"4","key":"1351_CR12","doi-asserted-by":"publisher","first-page":"1333","DOI":"10.1523\/JNEUROSCI.2477-13.2014","volume":"34","author":"DE Harlow","year":"2014","unstructured":"Harlow DE, Saul KE, Culp CM, Vesely EM, Macklin WB (2014) Expression of proteolipid protein gene in spinal cord stem cells and early oligodendrocyte progenitor cells is dispensable for normal cell migration and myelination. J Neurosci 34(4):1333\u20131343. \n                    https:\/\/doi.org\/10.1523\/JNEUROSCI.2477-13.2014","journal-title":"J Neurosci"},{"key":"1351_CR13","doi-asserted-by":"publisher","first-page":"7691","DOI":"10.1007\/s12035-018-0941-z","volume":"55","author":"S Ocklenburg","year":"2018","unstructured":"Ocklenburg S, Gerding WM, Raane M, Arning L, Gen\u00e7 E, Epplen JT, G\u00fcnt\u00fcrk\u00fcn O, Beste C (2018) PLP1 gene variation modulates leftward and rightward functional hemispheric asymmetries. Mol Neurobiol 55:7691\u20137700. \n                    https:\/\/doi.org\/10.1007\/s12035-018-0941-z","journal-title":"Mol Neurobiol"},{"issue":"2","key":"1351_CR14","doi-asserted-by":"publisher","first-page":"397","DOI":"10.1074\/mcp.M113.035600","volume":"13","author":"L Fagerberg","year":"2014","unstructured":"Fagerberg L, Hallstr\u00f6m BM, Oksvold P, Kampf C, Djureinovic D, Odeberg J, Habuka M, Tahmasebpoor S et al (2014) Analysis of the human tissue-specific expression by genome-wide integration of transcriptomics and antibody-based proteomics. Mol Cell Proteomics 13(2):397\u2013406. \n                    https:\/\/doi.org\/10.1074\/mcp.M113.035600","journal-title":"Mol Cell Proteomics"},{"issue":"4","key":"1351_CR15","doi-asserted-by":"publisher","first-page":"175909141772058","DOI":"10.1177\/1759091417720583","volume":"9","author":"PA Wight","year":"2017","unstructured":"Wight PA (2017) Effects of intron 1 sequences on human PLP1 expression: implications for PLP1-related disorders. ASN Neuro 9(4):1759091417720583. \n                    https:\/\/doi.org\/10.1177\/1759091417720583","journal-title":"ASN Neuro"},{"issue":"10","key":"1351_CR16","doi-asserted-by":"publisher","first-page":"1369","DOI":"10.1002\/nbm.1700","volume":"24","author":"T Ruest","year":"2011","unstructured":"Ruest T, Holmes WM, Barrie JA, Griffiths IR, Anderson TJ, Dewar D, Edgar JM (2011) High-resolution diffusion tensor imaging of fixed brain in a mouse model of Pelizaeus-Merzbacher disease: comparison with quantitative measures of white matter pathology. NMR Biomed 24(10):1369\u20131379. \n                    https:\/\/doi.org\/10.1002\/nbm.1700","journal-title":"NMR Biomed"},{"issue":"4","key":"1351_CR17","doi-asserted-by":"publisher","first-page":"1487","DOI":"10.1016\/j.neuroimage.2006.02.024","volume":"31","author":"SM Smith","year":"2006","unstructured":"Smith SM, Jenkinson M, Johansen-Berg H, Rueckert D, Nichols TE, Mackay CE, Watkins KE, Ciccarelli O et al (2006) Tract-based spatial statistics: voxelwise analysis of multi-subject diffusion data. Neuroimage 31(4):1487\u20131505. \n                    https:\/\/doi.org\/10.1016\/j.neuroimage.2006.02.024","journal-title":"Neuroimage"},{"issue":"6","key":"1351_CR18","doi-asserted-by":"publisher","first-page":"1329","DOI":"10.1002\/jmri.23774","volume":"36","author":"SF Dreha-Kulaczewski","year":"2012","unstructured":"Dreha-Kulaczewski SF, Brockmann K, Henneke M, Dechent P, Wilken B, G\u00e4rtner J, Helms G (2012) Assessment of myelination in hypomyelinating disorders by quantitative MRI. J Magn Reson Imaging 36(6):1329\u20131338. \n                    https:\/\/doi.org\/10.1002\/jmri.23774","journal-title":"J Magn Reson Imaging"},{"issue":"6","key":"1351_CR19","doi-asserted-by":"publisher","first-page":"571","DOI":"10.1016\/j.braindev.2015.12.007","volume":"38","author":"K Sumida","year":"2016","unstructured":"Sumida K, Inoue K, Takanashi J-I, Sasaki M, Watanabe K, Suzuki M, Kurahashi H, Omata T et al (2016) The magnetic resonance imaging spectrum of Pelizaeus-Merzbacher disease: a multicenter study of 19 patients. Brain and Development 38(6):571\u2013580. \n                    https:\/\/doi.org\/10.1016\/j.braindev.2015.12.007","journal-title":"Brain and Development"},{"issue":"10","key":"1351_CR20","first-page":"1822","volume":"20","author":"J Takanashi","year":"1999","unstructured":"Takanashi J, Sugita K, Tanabe Y, Nagasawa K, Inoue K, Osaka H, Kohno Y (1999) MR-revealed myelination in the cerebral corticospinal tract as a marker for Pelizaeus-Merzbacher\u2019s disease with proteolipid protein gene duplication. AJNR Am J Neuroradiol 20(10):1822\u20131828","journal-title":"AJNR Am J Neuroradiol"},{"issue":"1","key":"1351_CR21","doi-asserted-by":"publisher","first-page":"77","DOI":"10.1016\/S0010-9452(13)80076-7","volume":"26","author":"MT Banich","year":"1990","unstructured":"Banich MT, Belger A (1990) Interhemispheric interaction: how do the hemispheres divide and conquer a task? Cortex 26(1):77\u201394","journal-title":"Cortex"},{"issue":"5","key":"1351_CR22","doi-asserted-by":"publisher","first-page":"465","DOI":"10.1515\/revneuro-2015-0052","volume":"27","author":"S Ocklenburg","year":"2016","unstructured":"Ocklenburg S, Friedrich P, G\u00fcnt\u00fcrk\u00fcn O, Gen\u00e7 E (2016) Intrahemispheric white matter asymmetries: the missing link between brain structure and functional lateralization? Rev Neurosci 27(5):465\u2013480. \n                    https:\/\/doi.org\/10.1515\/revneuro-2015-0052","journal-title":"Rev Neurosci"},{"key":"1351_CR23","volume-title":"Introduction to diffusion tensor imaging: and higher order models","year":"2014","unstructured":"Tournier J-D, Mori S (eds) (2014) Introduction to diffusion tensor imaging: and higher order models, 2nd edn. Calif, Academic Press, Oxford, England, San Diego","edition":"2"},{"issue":"1","key":"1351_CR24","doi-asserted-by":"publisher","first-page":"144","DOI":"10.1016\/j.neuroimage.2006.09.018","volume":"34","author":"TEJ Behrens","year":"2007","unstructured":"Behrens TEJ, Berg HJ, Jbabdi S, Rushworth MFS, Woolrich MW (2007) Probabilistic diffusion tractography with multiple fibre orientations: what can we gain? Neuroimage 34(1):144\u2013155. \n                    https:\/\/doi.org\/10.1016\/j.neuroimage.2006.09.018","journal-title":"Neuroimage"},{"issue":"6","key":"1351_CR25","doi-asserted-by":"publisher","first-page":"469","DOI":"10.1038\/nrn1119","volume":"4","author":"D Bihan Le","year":"2003","unstructured":"Le Bihan D (2003) Looking into the functional architecture of the brain with diffusion MRI. Nat Rev Neurosci 4(6):469\u2013480. \n                    https:\/\/doi.org\/10.1038\/nrn1119","journal-title":"Nat Rev Neurosci"},{"issue":"6","key":"1351_CR26","doi-asserted-by":"publisher","first-page":"893","DOI":"10.1002\/mrm.1910360612","volume":"36","author":"C Pierpaoli","year":"1996","unstructured":"Pierpaoli C, Basser PJ (1996) Toward a quantitative assessment of diffusion anisotropy. Magn Reson Med 36(6):893\u2013906","journal-title":"Magn Reson Med"},{"key":"1351_CR27","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.bbr.2015.07.016","volume":"293","author":"E Gen\u00e7","year":"2015","unstructured":"Gen\u00e7 E, Ocklenburg S, Singer W, G\u00fcnt\u00fcrk\u00fcn O (2015) Abnormal interhemispheric motor interactions in patients with callosal agenesis. Behav Brain Res 293:1\u20139. \n                    https:\/\/doi.org\/10.1016\/j.bbr.2015.07.016","journal-title":"Behav Brain Res"},{"issue":"4","key":"1351_CR28","doi-asserted-by":"publisher","first-page":"528","DOI":"10.1038\/nn.3045","volume":"15","author":"RJ Zatorre","year":"2012","unstructured":"Zatorre RJ, Fields RD, Johansen-Berg H (2012) Plasticity in gray and white: neuroimaging changes in brain structure during learning. Nat Neurosci 15(4):528\u2013536. \n                    https:\/\/doi.org\/10.1038\/nn.3045","journal-title":"Nat Neurosci"},{"issue":"7","key":"1351_CR29","doi-asserted-by":"publisher","first-page":"874","DOI":"10.1016\/j.mri.2008.01.047","volume":"26","author":"B M\u00e4dler","year":"2008","unstructured":"M\u00e4dler B, Drabycz SA, Kolind SH, Whittall KP, MacKay AL (2008) Is diffusion anisotropy an accurate monitor of myelination? Correlation of multicomponent T2 relaxation and diffusion tensor anisotropy in human brain. Magn Reson Imaging 26(7):874\u2013888. \n                    https:\/\/doi.org\/10.1016\/j.mri.2008.01.047","journal-title":"Magn Reson Imaging"},{"issue":"7\u20138","key":"1351_CR30","doi-asserted-by":"publisher","first-page":"435","DOI":"10.1002\/nbm.782","volume":"15","author":"C Beaulieu","year":"2002","unstructured":"Beaulieu C (2002) The basis of anisotropic water diffusion in the nervous system\u2014a technical review. NMR Biomed 15(7\u20138):435\u2013455. \n                    https:\/\/doi.org\/10.1002\/nbm.782","journal-title":"NMR Biomed"},{"issue":"5","key":"1351_CR31","doi-asserted-by":"publisher","first-page":"527","DOI":"10.1016\/j.neuron.2006.08.012","volume":"51","author":"S Mori","year":"2006","unstructured":"Mori S, Zhang J (2006) Principles of diffusion tensor imaging and its applications to basic neuroscience research. Neuron 51(5):527\u2013539. \n                    https:\/\/doi.org\/10.1016\/j.neuron.2006.08.012","journal-title":"Neuron"},{"issue":"1","key":"1351_CR32","doi-asserted-by":"publisher","first-page":"533","DOI":"10.1016\/j.neuroimage.2012.06.064","volume":"63","author":"T Prasloski","year":"2012","unstructured":"Prasloski T, Rauscher A, MacKay AL et al (2012) Rapid whole cerebrum myelin water imaging using a 3D GRASE sequence. Neuroimage 63(1):533\u2013539. \n                    https:\/\/doi.org\/10.1016\/j.neuroimage.2012.06.064","journal-title":"Neuroimage"},{"issue":"3","key":"1351_CR33","doi-asserted-by":"publisher","first-page":"e3868","DOI":"10.1002\/nbm.3868","volume":"31","author":"Md Nasir Uddin","year":"2018","unstructured":"Uddin MN, Figley TD, Marrie RA, Figley CR, for the CCOMS Study Group (2018) Can T1 w\/T2 w ratio be used as a myelin-specific measure in subcortical structures? Comparisons between FSE-based T1 w\/T2 w ratios, GRASE-based T1 w\/T2 w ratios and multi-echo GRASE-based myelin water fractions. NMR Biomed 31(3). \n                    https:\/\/doi.org\/10.1002\/nbm.3868","journal-title":"NMR in Biomedicine"},{"issue":"1","key":"1351_CR34","doi-asserted-by":"publisher","first-page":"34","DOI":"10.1002\/mrm.1910370107","volume":"37","author":"KP Whittall","year":"1997","unstructured":"Whittall KP, MacKay AL, Graeb DA et al (1997) In vivo measurement of T2 distributions and water contents in normal human brain. Magn Reson Med 37(1):34\u201343","journal-title":"Magn Reson Med"},{"issue":"1","key":"1351_CR35","doi-asserted-by":"publisher","first-page":"134","DOI":"10.1016\/0022-2364(89)90011-5","volume":"84","author":"KP Whittall","year":"1989","unstructured":"Whittall KP, MacKay AL (1989) Quantitative interpretation of NMR relaxation data. J Magn Reson (1969) 84(1):134\u2013152. \n                    https:\/\/doi.org\/10.1016\/0022-2364(89)90011-5","journal-title":"J Magn Reson (1969)"},{"issue":"4","key":"1351_CR36","doi-asserted-by":"publisher","first-page":"1575","DOI":"10.1016\/j.neuroimage.2007.12.008","volume":"40","author":"C Laule","year":"2008","unstructured":"Laule C, Kozlowski P, Leung E, Li DKB, MacKay AL, Moore GRW (2008) Myelin water imaging of multiple sclerosis at 7 T: correlations with histopathology. Neuroimage 40(4):1575\u20131580. \n                    https:\/\/doi.org\/10.1016\/j.neuroimage.2007.12.008","journal-title":"Neuroimage"},{"issue":"6","key":"1351_CR37","doi-asserted-by":"publisher","first-page":"1445","DOI":"10.1002\/jmri.24106","volume":"38","author":"SM Meyers","year":"2013","unstructured":"Meyers SM, Vavasour IM, M\u00e4dler B, Harris T, Fu E, Li DKB, Traboulsee AL, MacKay AL et al (2013) Multicenter measurements of myelin water fraction and geometric mean T2: intra- and intersite reproducibility. J Magn Reson Imaging 38(6):1445\u20131453. \n                    https:\/\/doi.org\/10.1002\/jmri.24106","journal-title":"J Magn Reson Imaging"},{"issue":"1","key":"1351_CR38","doi-asserted-by":"publisher","first-page":"71","DOI":"10.3233\/BPL-160033","volume":"2","author":"AL MacKay","year":"2016","unstructured":"MacKay AL, Laule C (2016) Magnetic resonance of myelin water: an in vivo marker for myelin. Brain Plast 2(1):71\u201391. \n                    https:\/\/doi.org\/10.3233\/BPL-160033","journal-title":"Brain Plast"},{"issue":"1","key":"1351_CR39","doi-asserted-by":"publisher","first-page":"70","DOI":"10.1002\/mrm.25198","volume":"73","author":"E Alonso-Ortiz","year":"2015","unstructured":"Alonso-Ortiz E, Levesque IR, Pike GB (2015) MRI-based myelin water imaging: a technical review. Magn Reson Med 73(1):70\u201381. \n                    https:\/\/doi.org\/10.1002\/mrm.25198","journal-title":"Magn Reson Med"},{"issue":"2","key":"1351_CR40","doi-asserted-by":"publisher","first-page":"218","DOI":"10.1016\/0022-2364(86)90074-0","volume":"69","author":"RM Kroeker","year":"1986","unstructured":"Kroeker RM, Mark Henkelman R (1986) Analysis of biological NMR relaxation data with continuous distributions of relaxation times. J Magn Reson (1969) 69(2):218\u2013235. \n                    https:\/\/doi.org\/10.1016\/0022-2364(86)90074-0","journal-title":"J Magn Reson (1969)"},{"issue":"6","key":"1351_CR41","doi-asserted-by":"publisher","first-page":"747","DOI":"10.1177\/1352458506070928","volume":"12","author":"C Laule","year":"2006","unstructured":"Laule C, Leung E, Lis DKB et al (2006) Myelin water imaging in multiple sclerosis: quantitative correlations with histopathology. Mult Scler 12(6):747\u2013753. \n                    https:\/\/doi.org\/10.1177\/1352458506070928","journal-title":"Mult Scler"},{"issue":"6","key":"1351_CR42","doi-asserted-by":"publisher","first-page":"2107","DOI":"10.1016\/j.neurobiolaging.2015.02.029","volume":"36","author":"T Billiet","year":"2015","unstructured":"Billiet T, Vandenbulcke M, M\u00e4dler B, Peeters R, Dhollander T, Zhang H, Deprez S, van den Bergh BRH et al (2015) Age-related microstructural differences quantified using myelin water imaging and advanced diffusion MRI. Neurobiol Aging 36(6):2107\u20132121. \n                    https:\/\/doi.org\/10.1016\/j.neurobiolaging.2015.02.029","journal-title":"Neurobiol Aging"},{"issue":"4436","key":"1351_CR43","doi-asserted-by":"publisher","first-page":"1226","DOI":"10.1126\/science.7355287","volume":"207","author":"RC Gur","year":"1980","unstructured":"Gur RC, Packer IK, Hungerbuhler JP, Reivich M, Obrist W, Amarnek W, Sackeim H (1980) Differences in the distribution of gray and white matter in human cerebral hemispheres. Science 207(4436):1226\u20131228","journal-title":"Science"},{"issue":"10","key":"1351_CR44","doi-asserted-by":"publisher","first-page":"1245","DOI":"10.1038\/nn.2905","volume":"14","author":"M Thiebaut de Schotten","year":"2011","unstructured":"Thiebaut de Schotten M, Dell'Acqua F, Forkel SJ et al (2011) A lateralized brain network for visuospatial attention. Nat Neurosci 14(10):1245\u20131246. \n                    https:\/\/doi.org\/10.1038\/nn.2905","journal-title":"Nat Neurosci"},{"issue":"1","key":"1351_CR45","doi-asserted-by":"publisher","first-page":"97","DOI":"10.1016\/0028-3932(71)90067-4","volume":"9","author":"RC Oldfield","year":"1971","unstructured":"Oldfield RC (1971) The assessment and analysis of handedness: the Edinburgh inventory. Neuropsychologia 9(1):97\u2013113","journal-title":"Neuropsychologia"},{"issue":"13","key":"1351_CR46","doi-asserted-by":"publisher","first-page":"3568","DOI":"10.1093\/nar\/gkg616","volume":"31","author":"L Cartegni","year":"2003","unstructured":"Cartegni L, Wang J, Zhu Z, Zhang MQ, Krainer AR (2003) ESEfinder: a web resource to identify exonic splicing enhancers. Nucleic Acids Res 31(13):3568\u20133571","journal-title":"Nucleic Acids Res"},{"issue":"5583","key":"1351_CR47","doi-asserted-by":"publisher","first-page":"1007","DOI":"10.1126\/science.1073774","volume":"297","author":"WG Fairbrother","year":"2002","unstructured":"Fairbrother WG, Yeh R-F, Sharp PA, Burge CB (2002) Predictive identification of exonic splicing enhancers in human genes. Science 297(5583):1007\u20131013. \n                    https:\/\/doi.org\/10.1126\/science.1073774","journal-title":"Science"},{"issue":"2","key":"1351_CR48","doi-asserted-by":"publisher","first-page":"179","DOI":"10.1006\/nimg.1998.0395","volume":"9","author":"AM Dale","year":"1999","unstructured":"Dale AM, Fischl B, Sereno MI (1999) Cortical surface-based analysis. I. Segmentation and surface reconstruction. Neuroimage 9(2):179\u2013194. \n                    https:\/\/doi.org\/10.1006\/nimg.1998.0395","journal-title":"Neuroimage"},{"issue":"2","key":"1351_CR49","doi-asserted-by":"publisher","first-page":"195","DOI":"10.1006\/nimg.1998.0396","volume":"9","author":"B Fischl","year":"1999","unstructured":"Fischl B, Sereno MI, Dale AM (1999) Cortical surface-based analysis. II: Inflation, flattening, and a surface-based coordinate system. Neuroimage 9(2):195\u2013207. \n                    https:\/\/doi.org\/10.1006\/nimg.1998.0396","journal-title":"Neuroimage"},{"issue":"4","key":"1351_CR50","doi-asserted-by":"publisher","first-page":"1247","DOI":"10.1016\/j.neuroimage.2008.10.030","volume":"44","author":"DH Salat","year":"2009","unstructured":"Salat DH, Greve DN, Pacheco JL et al (2009) Regional white matter volume differences in nondemented aging and Alzheimer\u2019s disease. Neuroimage 44(4):1247\u20131258. \n                    https:\/\/doi.org\/10.1016\/j.neuroimage.2008.10.030","journal-title":"Neuroimage"},{"issue":"1","key":"1351_CR51","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0084914","volume":"9","author":"D Klein","year":"2014","unstructured":"Klein D, Rotarska-Jagiela A, Genc E, Sritharan S, Mohr H, Roux F, Han CE, Kaiser M et al (2014) Adolescent brain maturation and cortical folding: evidence for reductions in gyrification. PLoS One 9(1):e84914. \n                    https:\/\/doi.org\/10.1371\/journal.pone.0084914","journal-title":"PLoS One"},{"issue":"3","key":"1351_CR52","doi-asserted-by":"publisher","first-page":"968","DOI":"10.1016\/j.neuroimage.2006.01.021","volume":"31","author":"RS Desikan","year":"2006","unstructured":"Desikan RS, S\u00e9gonne F, Fischl B, Quinn BT, Dickerson BC, Blacker D, Buckner RL, Dale AM et al (2006) An automated labeling system for subdividing the human cerebral cortex on MRI scans into gyral based regions of interest. Neuroimage 31(3):968\u2013980. \n                    https:\/\/doi.org\/10.1016\/j.neuroimage.2006.01.021","journal-title":"Neuroimage"},{"issue":"3","key":"1351_CR53","doi-asserted-by":"publisher","first-page":"527","DOI":"10.1002\/mrm.10391","volume":"49","author":"J Hennig","year":"2003","unstructured":"Hennig J, Weigel M, Scheffler K (2003) Multiecho sequences with variable refocusing flip angles: optimization of signal behavior using smooth transitions between pseudo steady states (TRAPS). Magn Reson Med 49(3):527\u2013535. \n                    https:\/\/doi.org\/10.1002\/mrm.10391","journal-title":"Magn Reson Med"},{"issue":"2","key":"1351_CR54","doi-asserted-by":"publisher","first-page":"210","DOI":"10.1037\/a0014265","volume":"23","author":"C Chiarello","year":"2009","unstructured":"Chiarello C, Welcome SE, Halderman LK, Towler S, Julagay J, Otto R, Leonard CM (2009) A large-scale investigation of lateralization in cortical anatomy and word reading: are there sex differences? Neuropsychology 23(2):210\u2013222. \n                    https:\/\/doi.org\/10.1037\/a0014265","journal-title":"Neuropsychology"},{"key":"1351_CR55","doi-asserted-by":"publisher","first-page":"32","DOI":"10.1016\/j.neulet.2014.07.044","volume":"580","author":"S Ocklenburg","year":"2014","unstructured":"Ocklenburg S, Schlaffke L, Hugdahl K, Westerhausen R (2014) From structure to function in the lateralized brain: how structural properties of the arcuate and uncinate fasciculus are associated with dichotic listening performance. Neurosci Lett 580:32\u201336. \n                    https:\/\/doi.org\/10.1016\/j.neulet.2014.07.044","journal-title":"Neurosci Lett"},{"key":"1351_CR56","doi-asserted-by":"publisher","first-page":"65","DOI":"10.1016\/j.cortex.2015.01.023","volume":"72","author":"C Thomas","year":"2015","unstructured":"Thomas C, Avram A, Pierpaoli C, Baker C (2015) Diffusion MRI properties of the human uncinate fasciculus correlate with the ability to learn visual associations. Cortex 72:65\u201378. \n                    https:\/\/doi.org\/10.1016\/j.cortex.2015.01.023","journal-title":"Cortex"},{"key":"1351_CR57","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.neuroscience.2012.11.038","volume":"231","author":"H Takao","year":"2013","unstructured":"Takao H, Hayashi N, Ohtomo K (2013) White matter microstructure asymmetry: effects of volume asymmetry on fractional anisotropy asymmetry. Neuroscience 231:1\u201312. \n                    https:\/\/doi.org\/10.1016\/j.neuroscience.2012.11.038","journal-title":"Neuroscience"},{"issue":"1","key":"1351_CR58","doi-asserted-by":"publisher","first-page":"49","DOI":"10.1016\/j.neuroimage.2010.07.055","volume":"54","author":"M Thiebaut de Schotten","year":"2011","unstructured":"Thiebaut de Schotten M, Ffytche DH, Bizzi A et al (2011) Atlasing location, asymmetry and inter-subject variability of white matter tracts in the human brain with MR diffusion tractography. Neuroimage 54(1):49\u201359. \n                    https:\/\/doi.org\/10.1016\/j.neuroimage.2010.07.055","journal-title":"Neuroimage"},{"issue":"2","key":"1351_CR59","doi-asserted-by":"publisher","first-page":"57","DOI":"10.1002\/nbm.683","volume":"14","author":"RM Henkelman","year":"2001","unstructured":"Henkelman RM, Stanisz GJ, Graham SJ (2001) Magnetization transfer in MRI: a review. NMR Biomed 14(2):57\u201364","journal-title":"NMR Biomed"},{"issue":"4","key":"1351_CR60","doi-asserted-by":"publisher","first-page":"1000","DOI":"10.1016\/j.neuroimage.2012.03.072","volume":"61","author":"H Zhang","year":"2012","unstructured":"Zhang H, Schneider T, Wheeler-Kingshott CA, Alexander DC (2012) NODDI: practical in vivo neurite orientation dispersion and density imaging of the human brain. Neuroimage 61(4):1000\u20131016. \n                    https:\/\/doi.org\/10.1016\/j.neuroimage.2012.03.072","journal-title":"Neuroimage"},{"issue":"1","key":"1351_CR61","doi-asserted-by":"publisher","first-page":"1905","DOI":"10.1038\/s41467-018-04268-8","volume":"9","author":"E Gen\u00e7","year":"2018","unstructured":"Gen\u00e7 E, Fraenz C, Schl\u00fcter C, Friedrich P, Hossiep R, Voelkle MC, Ling JM, G\u00fcnt\u00fcrk\u00fcn O et al (2018) Diffusion markers of dendritic density and arborization in gray matter predict differences in intelligence. Nat Commun 9(1):1905. \n                    https:\/\/doi.org\/10.1038\/s41467-018-04268-8","journal-title":"Nat Commun"},{"key":"1351_CR62","doi-asserted-by":"publisher","first-page":"28","DOI":"10.1016\/j.neuint.2015.02.006","volume":"83-84","author":"S Fj\u00e6r","year":"2015","unstructured":"Fj\u00e6r S, B\u00f8 L, Myhr K-M, Torkildsen \u00d8, Wergeland S (2015) Magnetization transfer ratio does not correlate to myelin content in the brain in the MOG-EAE mouse model. Neurochem Int 83-84:28\u201340. \n                    https:\/\/doi.org\/10.1016\/j.neuint.2015.02.006","journal-title":"Neurochem Int"},{"issue":"9","key":"1351_CR63","doi-asserted-by":"publisher","first-page":"663","DOI":"10.1002\/acn3.445","volume":"4","author":"F Grussu","year":"2017","unstructured":"Grussu F, Schneider T, Tur C, Yates RL, Tachrount M, Ianu\u015f A, Yiannakas MC, Newcombe J et al (2017) Neurite dispersion: a new marker of multiple sclerosis spinal cord pathology? Ann Clin Transl Neurol 4(9):663\u2013679. \n                    https:\/\/doi.org\/10.1002\/acn3.445","journal-title":"Ann Clin Transl Neurol"},{"issue":"41","key":"1351_CR64","doi-asserted-by":"publisher","first-page":"16170","DOI":"10.1523\/JNEUROSCI.1463-13.2013","volume":"33","author":"J O'Muircheartaigh","year":"2013","unstructured":"O'Muircheartaigh J, Dean DC, Dirks H, Waskiewicz N, Lehman K, Jerskey BA, Deoni SCL (2013) Interactions between white matter asymmetry and language during neurodevelopment. J Neurosci 33(41):16170\u201316177. \n                    https:\/\/doi.org\/10.1523\/JNEUROSCI.1463-13.2013","journal-title":"J Neurosci"},{"issue":"5","key":"1351_CR65","doi-asserted-by":"publisher","first-page":"461","DOI":"10.1001\/archpsyc.58.5.461","volume":"58","author":"G Bartzokis","year":"2001","unstructured":"Bartzokis G, Beckson M, Lu PH, Nuechterlein KH, Edwards N, Mintz J (2001) Age-related changes in frontal and temporal lobe volumes in men: a magnetic resonance imaging study. Arch Gen Psychiatry 58(5):461\u2013465","journal-title":"Arch Gen Psychiatry"},{"issue":"3","key":"1351_CR66","doi-asserted-by":"publisher","first-page":"309","DOI":"10.1038\/nn1008","volume":"6","author":"ER Sowell","year":"2003","unstructured":"Sowell ER, Peterson BS, Thompson PM, Welcome SE, Henkenius AL, Toga AW (2003) Mapping cortical change across the human life span. Nat Neurosci 6(3):309\u2013315. \n                    https:\/\/doi.org\/10.1038\/nn1008","journal-title":"Nat Neurosci"},{"key":"1351_CR67","doi-asserted-by":"publisher","first-page":"69","DOI":"10.1146\/annurev.genom.6.080604.162350","volume":"6","author":"JC Chow","year":"2005","unstructured":"Chow JC, Yen Z, Ziesche SM, Brown CJ (2005) Silencing of the mammalian X chromosome. Annu Rev Genomics Hum Genet 6:69\u201392. \n                    https:\/\/doi.org\/10.1146\/annurev.genom.6.080604.162350","journal-title":"Annu Rev Genomics Hum Genet"},{"key":"1351_CR68","doi-asserted-by":"publisher","first-page":"34","DOI":"10.1016\/j.bandc.2016.09.003","volume":"109","author":"S Ocklenburg","year":"2016","unstructured":"Ocklenburg S, Str\u00f6ckens F, Bless JJ, Hugdahl K, Westerhausen R, Manns M (2016) Investigating heritability of laterality and cognitive control in speech perception. Brain Cogn 109:34\u201339. \n                    https:\/\/doi.org\/10.1016\/j.bandc.2016.09.003","journal-title":"Brain Cogn"},{"key":"1351_CR69","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.bbr.2017.09.035","volume":"337","author":"J Schmitz","year":"2018","unstructured":"Schmitz J, Kumsta R, Moser D, G\u00fcnt\u00fcrk\u00fcn O, Ocklenburg S (2018) KIAA0319 promoter DNA methylation predicts dichotic listening performance in forced-attention conditions. Behav Brain Res 337:1\u20137. \n                    https:\/\/doi.org\/10.1016\/j.bbr.2017.09.035","journal-title":"Behav Brain Res"},{"issue":"4","key":"1351_CR70","doi-asserted-by":"publisher","first-page":"410","DOI":"10.1017\/S1355617712001476","volume":"19","author":"S Ocklenburg","year":"2013","unstructured":"Ocklenburg S, Westerhausen R, Hirnstein M, Hugdahl K (2013) Auditory hallucinations and reduced language lateralization in schizophrenia: a meta-analysis of dichotic listening studies. J Int Neuropsychol Soc 19(4):410\u2013418. \n                    https:\/\/doi.org\/10.1017\/S1355617712001476","journal-title":"J Int Neuropsychol Soc"},{"issue":"1","key":"1351_CR71","doi-asserted-by":"publisher","first-page":"284","DOI":"10.1016\/j.bbr.2011.07.042","volume":"225","author":"S Ocklenburg","year":"2011","unstructured":"Ocklenburg S, Arning L, Hahn C, Gerding WM, Epplen JT, G\u00fcnt\u00fcrk\u00fcn O, Beste C (2011) Variation in the NMDA receptor 2B subunit gene GRIN2B is associated with differential language lateralization. Behav Brain Res 225(1):284\u2013289. \n                    https:\/\/doi.org\/10.1016\/j.bbr.2011.07.042","journal-title":"Behav Brain Res"},{"issue":"2","key":"1351_CR72","doi-asserted-by":"publisher","first-page":"137","DOI":"10.1017\/S1740925X09990238","volume":"4","author":"RM Gould","year":"2008","unstructured":"Gould RM, Oakley T, Goldstone JV, Dugas JC, Brady ST, Gow A (2008) Myelin sheaths are formed with proteins that originated in vertebrate lineages. Neuron Glia Biol 4(2):137\u2013152. \n                    https:\/\/doi.org\/10.1017\/S1740925X09990238","journal-title":"Neuron Glia Biol"},{"issue":"4","key":"1351_CR73","doi-asserted-by":"publisher","first-page":"285","DOI":"10.1038\/nrg775","volume":"3","author":"L Cartegni","year":"2002","unstructured":"Cartegni L, Chew SL, Krainer AR (2002) Listening to silence and understanding nonsense: exonic mutations that affect splicing. Nat Rev Genet 3(4):285\u2013298. \n                    https:\/\/doi.org\/10.1038\/nrg775","journal-title":"Nat Rev Genet"}],"container-title":["Molecular Neurobiology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s12035-018-1351-y.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s12035-018-1351-y\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s12035-018-1351-y.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,9,20]],"date-time":"2019-09-20T19:21:35Z","timestamp":1569007295000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s12035-018-1351-y"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,9,21]]},"references-count":73,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2019,6]]}},"alternative-id":["1351"],"URL":"https:\/\/doi.org\/10.1007\/s12035-018-1351-y","relation":{},"ISSN":["0893-7648","1559-1182"],"issn-type":[{"value":"0893-7648","type":"print"},{"value":"1559-1182","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,9,21]]},"assertion":[{"value":"13 July 2018","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"13 September 2018","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"21 September 2018","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"The study was approved by the local ethics committee of the Faculty of Psychology at Ruhr University Bochum. All participants gave their written informed consent and were treated in accordance with the Declaration of Helsinki.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with Ethical Standards"}}]}}