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All procedures performed in studies involving animals were in accordance with the ethical standards of the institution or practice at which the studies were conducted. All procedures were approved by the local governing body for animal welfare (Regierungspr\u00e4sidium Karlsruhe).","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with Ethical Standards"}},{"value":"The authors declare no potential conflicts of interest with respect to the research, authorship, and\/or publication of this article. DM is one of the founders and shareholders of FundaMental Pharma GmbH.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of Interest"}}]}}