{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T13:37:01Z","timestamp":1790257021268,"version":"4.1.0"},"reference-count":53,"publisher":"Springer Science and Business Media LLC","issue":"11","license":[{"start":{"date-parts":[[2019,5,10]],"date-time":"2019-05-10T00:00:00Z","timestamp":1557446400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Mol Neurobiol"],"published-print":{"date-parts":[[2019,11]]},"DOI":"10.1007\/s12035-019-1573-7","type":"journal-article","created":{"date-parts":[[2019,5,10]],"date-time":"2019-05-10T20:07:57Z","timestamp":1557518877000},"page":"7608-7616","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":27,"title":["Neurocognitive Impairment in mdx Mice"],"prefix":"10.1007","volume":"56","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4991-042X","authenticated-orcid":false,"given":"Clarissa M.","family":"Comim","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Let\u00edcia","family":"Ventura","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Viviane","family":"Freiberger","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paula","family":"Dias","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daiane","family":"Bragagnolo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matheus L.","family":"Dutra","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ricardo A.","family":"Amaral","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ana Lucia S.","family":"Camargo-Fagundes","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patr\u00edcia A.","family":"Reis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hugo C.","family":"Castro-Faria-Neto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mariz","family":"Vainzof","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria I.","family":"Rosa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2019,5,10]]},"reference":[{"key":"1573_CR1","doi-asserted-by":"crossref","first-page":"993","DOI":"10.4103\/neuroindia.NI_1241_16","volume":"65","author":"S Ram","year":"2017","unstructured":"Ram S (2017) Global muscular dystrophy research: a 25-year bibliometric perspective. Neurol India 65:993\u20131000","journal-title":"Neurol India"},{"key":"1573_CR2","doi-asserted-by":"crossref","first-page":"594","DOI":"10.1002\/1096-9861(20000710)422:4<594::AID-CNE8>3.0.CO;2-Q","volume":"422","author":"I Knuesel","year":"2000","unstructured":"Knuesel I, Bornhauser BC, Zuellig RA, Heller F, Schaub MC, Fritschy JM (2000) Differential expression of utrophin and dystrophin in CNS neurons: an insitu hybridization and immunohistochemical study. J Comp Neurol 422:594\u2013611","journal-title":"J Comp Neurol"},{"key":"1573_CR3","doi-asserted-by":"crossref","first-page":"1304","DOI":"10.1152\/jn.00248.2016","volume":"116","author":"MG Rae","year":"2016","unstructured":"Rae MG, O\u2019Malley D (2016) Cognitive dysfunction in Duchenne muscular dystrophy: a possible role for neuromodulatory immune molecules. J Neurophysiol 116:1304\u20131315","journal-title":"J Neurophysiol"},{"key":"1573_CR4","doi-asserted-by":"crossref","first-page":"775","DOI":"10.1016\/j.nmd.2016.08.006","volume":"26","author":"R Miranda","year":"2016","unstructured":"Miranda R, Laroche S, Vaillend C (2016) Reduced neuronal density in the CA1 anterodorsal hippocampus of the mdx mouse. Neuromuscul Disord 26:775\u2013781","journal-title":"Neuromuscul Disord"},{"key":"1573_CR5","doi-asserted-by":"crossref","first-page":"802","DOI":"10.1016\/j.neuint.2009.08.003","volume":"55","author":"CM Comim","year":"2009","unstructured":"Comim CM, Cassol OJ Jr, Constantino LC, Constantino LS, Petronilho F, Tuon L, Vainzof M, Dal-Pizzol F et al (2009) Oxidative variables and antioxidant enzymes activities in the mdx mouse brain. Neurochem Int 55:802\u2013805","journal-title":"Neurochem Int"},{"key":"1573_CR6","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1002\/mus.21559","volume":"41","author":"L Tuon","year":"2010","unstructured":"Tuon L, Comim CM, Fraga DB, Scaini G, Rezin GT, Baptista BR, Streck EL, Vainzof M et al (2010) Mitochondrial respiratory chain and creatine kinase activities in mdx mouse brain. Muscle Nerve 41:257\u2013260","journal-title":"Muscle Nerve"},{"key":"1573_CR7","first-page":"1041","volume":"26","author":"C Vaillend","year":"2017","unstructured":"Vaillend C, Chaussenot R (2017) Relationships linking emotional, motor, cognitive and GABAergic dysfunctions in dystrophin-deficient mdx mice. Hum Mol Genet 26:1041\u20131055","journal-title":"Hum Mol Genet"},{"key":"1573_CR8","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1016\/j.nmd.2011.02.017","volume":"21","author":"CM Comim","year":"2011","unstructured":"Comim CM, Moraz T, Abreu I, Fraga DB, Ghedim FV, Mildner N, Tuon L, Vainzof M et al (2011) Reduction of acethylcolinesterase activity in the brain of mdx mice. Neuromuscul Disord 21:359\u2013362","journal-title":"Neuromuscul Disord"},{"key":"1573_CR9","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1002\/mus.24704","volume":"53","author":"CM Comim","year":"2016","unstructured":"Comim CM, Hoepers A, Ventura L, Freiberger V, Dominguini D, Mina F, Mendon\u00e7a BP, Scaini G et al (2016) Activity of Krebs cycle enzymes in mdx mice. Muscle Nerve 53:91\u201395","journal-title":"Muscle Nerve"},{"key":"1573_CR10","doi-asserted-by":"crossref","first-page":"480","DOI":"10.1038\/ejhg.2013.169","volume":"22","author":"AP de Brouwer","year":"2014","unstructured":"de Brouwer AP, Nabuurs SB, Verhaart IE, Oudakker AR, Hordijk R, Yntema HG, Hordijk-Hos JM, Voesenek K et al (2014) A 3-base pair deletion, c.9711_9713del, in DMD results in intellectual disability without muscular dystrophy. Eur J Hum Genet 22:480\u2013485","journal-title":"Eur J Hum Genet"},{"key":"1573_CR11","doi-asserted-by":"crossref","first-page":"743","DOI":"10.1016\/j.neubiorev.2013.03.016","volume":"37","author":"WM Snow","year":"2013","unstructured":"Snow WM, Anderson JE, Jakobson LS (2013) Neuropsychological and neurobehavioral functioning in Duchenne muscular dystrophy: a review. Neurosci Biobehav Rev 37:743\u2013752","journal-title":"Neurosci Biobehav Rev"},{"issue":"36C","key":"1573_CR12","first-page":"55","volume":"14","author":"G Piccini","year":"2014","unstructured":"Piccini G, Gazzellini S, D\u2019Amico A, Pane M, Castelli E, Vicari S (2014) Developmental lag of visuospatial attention in Duchenne muscular dystrophy. Res Dev Disabil 14(36C):55\u201361","journal-title":"Res Dev Disabil"},{"key":"1573_CR13","doi-asserted-by":"crossref","first-page":"559","DOI":"10.1212\/WNL.55.4.559","volume":"55","author":"G Felisari","year":"2000","unstructured":"Felisari G, Martinelli Boneschi F, Bardoni A, Sironi M, Comi GP, Robotti M, Turconi AC, Lai M et al (2000) Loss of Dp140 dystrophin. Isoform and intellectual impairment in Duchenne dystrophy. Neurology 55:559\u2013564","journal-title":"Neurology"},{"key":"1573_CR14","doi-asserted-by":"crossref","first-page":"6","DOI":"10.2223\/JPED.2148","volume":"88","author":"F Nardes","year":"2012","unstructured":"Nardes F, Araujo AP, Ribeiro MG (2012) Mental retardation in Duchenne muscular dystrophy. J Pediatr 88:6\u201316","journal-title":"J Pediatr"},{"key":"1573_CR15","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1016\/j.nbd.2004.05.004","volume":"17","author":"C Vaillend","year":"2004","unstructured":"Vaillend C, Billard JM, Laroche S (2004) Impaired long-term spatial and recognition memory and enhanced CA1 hippocampal LTP in the dystrophin-deficient Dmd(mdx) mouse. Neurobiol Dis 17:10\u201320","journal-title":"Neurobiol Dis"},{"key":"1573_CR16","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1016\/0960-8966(91)90059-2","volume":"1","author":"F Muntoni","year":"1991","unstructured":"Muntoni F, Mateddu A, Serra G (1991) Passive avoidance behaviour deficit in the mdx mouse. Neuromuscul Disord 1:121\u2013123","journal-title":"Neuromuscul Disord"},{"key":"1573_CR17","first-page":"540370","volume":"1","author":"B de Paepe","year":"2013","unstructured":"de Paepe B, De Bleecker JL (2013) Cytokines and chemokines as regulators of skeletal muscle inflammation: presenting the case of Duchenne muscular dystrophy. Mediat Inflamm 1:540370","journal-title":"Mediat Inflamm"},{"key":"1573_CR18","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1093\/hmg\/11.3.263","volume":"11","author":"JD Porter","year":"2002","unstructured":"Porter JD, Khanna S, Kaminski HJ, Rao JS, Merriam AP, Richmonds CR, Leahy P, Li J et al (2002) A chronic inflammatory response dominates the skeletal muscle molecular signature in dystrophin-deficient mdx mice. Hum Mol Genet 11:263\u2013272","journal-title":"Hum Mol Genet"},{"key":"1573_CR19","doi-asserted-by":"crossref","first-page":"1809","DOI":"10.1590\/0001-3765201520140508","volume":"87","author":"CM Comim","year":"2015","unstructured":"Comim CM, Mathia GB, Hoepers A, Tuon L, Kapczinski F, Dal-Pizzol F, Quevedo J, Rosa MI (2015) Neurotrophins, cytokines, oxidative parameters and functionality in progressive muscular dystrophies. An Acad Bras Cienc 87:1809\u20131818","journal-title":"An Acad Bras Cienc"},{"key":"1573_CR20","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1007\/s00401-002-0635-4","volume":"105","author":"S Kuru","year":"2003","unstructured":"Kuru S, Inukai A, Kato T, Liang Y, Kimura S, Sobue G (2003) Expression of tumor necrosis factor-alpha in regenerating muscle fibers in inflammatory and non-inflammatory myopathies. Acta Neuropathol 105:217\u2013224","journal-title":"Acta Neuropathol"},{"key":"1573_CR21","doi-asserted-by":"crossref","first-page":"543","DOI":"10.1055\/s-0037-1614521","volume":"81","author":"E Porreca","year":"1999","unstructured":"Porreca E, Guglielmi MD, Uncini A, Di Gregorio P, Angelini A, Di Febbo C, Pierdomenico SD, Baccante G et al (1999) Haemostatic abnormalities, cardiac involvement and serum tumor necrosis factor levels in X-linked dystrophic patients. Thromb Haemost 81:543\u2013546","journal-title":"Thromb Haemost"},{"key":"1573_CR22","doi-asserted-by":"crossref","first-page":"755","DOI":"10.1016\/j.pmrj.2009.04.010","volume":"1","author":"NP Evans","year":"2009","unstructured":"Evans NP, Misyak SA, Robertson JL, Bassaganya-Riera J, Grange RW (2009) Immune-mediated mechanisms potentially regulate the disease time-course of duchenne muscular dystrophy and provide targets for therapeutic intervention. PM R 1:755\u2013768","journal-title":"PM R"},{"key":"1573_CR23","doi-asserted-by":"crossref","first-page":"601","DOI":"10.1101\/lm.028357.112","volume":"20","author":"I Marin","year":"2013","unstructured":"Marin I, Kipnis J (2013) Learning and memory ... and the immune system. Learn Mem 20:601\u2013606","journal-title":"Learn Mem"},{"key":"1573_CR24","doi-asserted-by":"crossref","first-page":"47","DOI":"10.2174\/1567202052773481","volume":"2","author":"B Nico","year":"2005","unstructured":"Nico B, Roncali L, Mangieri D, Ribatti D (2005) Blood-brain barrier alterations in MDX mouse, an animal model of the Duchenne muscular dystrophy. Curr Neurovasc Res 2:47\u201354","journal-title":"Curr Neurovasc Res"},{"key":"1573_CR25","doi-asserted-by":"crossref","first-page":"835","DOI":"10.1016\/j.neuroscience.2006.02.077","volume":"140","author":"B Nico","year":"2006","unstructured":"Nico B, Corsi P, Ria R, Crivellato E, Vacca A, Roccaro AM, Mangieri D, Ribatti D et al (2006) Increased matrix-metalloproteinase-2 and matrix-metalloproteinase-9 expression in the brain of dystrophic mdx mouse. Neuroscience 140:835\u2013848","journal-title":"Neuroscience"},{"key":"1573_CR26","doi-asserted-by":"crossref","first-page":"111","DOI":"10.3389\/fnmol.2018.00111","volume":"11","author":"D Pozzi","year":"2018","unstructured":"Pozzi D, Menna E, Canzi A, Desiato G, Mantovani C, Matteoli M (2018) The communication between the immune and nervous systems: the role of IL-1\u03b2 in synaptopathies. Front Mol Neurosci 11:111","journal-title":"Front Mol Neurosci"},{"key":"1573_CR27","doi-asserted-by":"crossref","first-page":"1045","DOI":"10.1016\/j.neubiorev.2006.03.006","volume":"36","author":"MP Leussis","year":"2006","unstructured":"Leussis MP, Bolivar VJ (2006) Habituation in rodents: a review of behavior, neurobiology, and genetics. Neurosci Biobehav Rev 36:1045\u20131064","journal-title":"Neurosci Biobehav Rev"},{"key":"1573_CR28","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1016\/S0014-2999(03)01278-0","volume":"463","author":"SF De Boer","year":"2003","unstructured":"De Boer SF, Koolhaas JM (2003) Defensive burying in rodents: ethology, neurobiology and psychopharmacology. Eur J Pharmacol 463:145\u2013161","journal-title":"Eur J Pharmacol"},{"key":"1573_CR29","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1016\/j.bbr.2014.08.002","volume":"285","author":"SJ Cohena","year":"2015","unstructured":"Cohena SJ, Stackman RW Jr (2015) Assessing rodent hippocampal involvement in the novel object recognition task. A review. Behav Brain Res 285:105\u2013117","journal-title":"Behav Brain Res"},{"key":"1573_CR30","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1016\/0165-0270(85)90031-7","volume":"14","author":"S Pellow","year":"1985","unstructured":"Pellow S, Chopin P, File SE, Briley M (1985) Validation of open: closed arm entries in an elevated plus-maze as a measure of anxiety in the rat. J Neurosci Methods 14:149\u2013167","journal-title":"J Neurosci Methods"},{"key":"1573_CR31","first-page":"1193","volume-title":"Psychopharmacology: the third generation of progress","author":"K Rickels","year":"1987","unstructured":"Rickels K, Schweizer EE (1987) Current pharmacotherapy in anxiety and panic. In: Meltzer HY (ed) Psychopharmacology: the third generation of progress. Raven, New York, pp. 1193\u20131203"},{"key":"1573_CR32","first-page":"139","volume":"30","author":"RD Porsolt","year":"1979","unstructured":"Porsolt RD (1979) Animal model of depression. Biomedicine 30:139\u2013140","journal-title":"Biomedicine"},{"key":"1573_CR33","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1016\/S0166-4328(00)00314-4","volume":"118","author":"H Einat","year":"2001","unstructured":"Einat H, Clenet F, Shaldubina A, Belmaker RH, Bourin M (2001) The antidepressant activity of inositol in the forced swim test involves 5-HT(2) receptors. Behav Brain Res 118:77\u201383","journal-title":"Behav Brain Res"},{"key":"1573_CR34","doi-asserted-by":"crossref","first-page":"2127","DOI":"10.1212\/WNL.54.11.2127","volume":"54","author":"VJ Hinton","year":"2000","unstructured":"Hinton VJ, De Vivo BC, Nereo NE (2000) Poor verbal working memory across intellectual level in boys with Duchenne dystrophy. Neurolog 54:2127\u20132132","journal-title":"Neurolog"},{"key":"1573_CR35","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1111\/j.1469-8749.1998.tb15351.x","volume":"40","author":"C Billard","year":"1998","unstructured":"Billard C, Gillet P, Barthez M-A (1998) Reading ability and processing in Duchenne muscular dystrophy and spinal muscular atrophy. Dev Med Child Neurol 40:12\u201320","journal-title":"Dev Med Child Neurol"},{"key":"1573_CR36","first-page":"267","volume":"55","author":"M Roccella","year":"2003","unstructured":"Roccella M, Pace R, De Gregorio MT (2003) Psychopathological assessment in children affected by Duchenne de Boulogne muscular dystrophy. Minerva Pediatr 55:267\u2013276","journal-title":"Minerva Pediatr"},{"key":"1573_CR37","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1016\/S0163-1047(86)90927-1","volume":"46","author":"PE Gold","year":"1986","unstructured":"Gold PE (1986) The use of avoidance training in studies of modulation of memory storage. Behav Neural Biol 46:87\u201398","journal-title":"Behav Neural Biol"},{"key":"1573_CR38","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1002\/ana.24222","volume":"76","author":"N Doorenweerd","year":"2014","unstructured":"Doorenweerd N, Straathof CS, Dumas EM, Spitali P, Ginjaar IB, Wokke BH, Schrans DG, van den Bergen JC et al (2014) Reduced cerebral gray matter and altered white matter in boys with Duchenne muscular dystrophy. Ann Neurol 76:403\u2013411","journal-title":"Ann Neurol"},{"key":"1573_CR39","doi-asserted-by":"crossref","first-page":"e0194636","DOI":"10.1371\/journal.pone.0194636","volume":"13","author":"B Kogelman","year":"2018","unstructured":"Kogelman B, Khmelinskii A, Verhaart I, Vliet LV, Bink DI, Aartsma-Rus A, Putten MV, Weerd LV (2018) Influence of full-length dystrophin on brain volumes in mouse models of Duchenne muscular dystrophy. PLoS One 13:e0194636","journal-title":"PLoS One"},{"key":"1573_CR40","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1186\/s12868-017-0381-0","volume":"18","author":"A Aranmolate","year":"2017","unstructured":"Aranmolate A, Tse N, Colognato H (2017) Myelination is delayed during postnatal brain development in the mdx mouse model of Duchenne muscular dystrophy. BMC Neurosci 18:63","journal-title":"BMC Neurosci"},{"key":"1573_CR41","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1016\/j.neulet.2009.04.065","volume":"459","author":"CM Comim","year":"2009","unstructured":"Comim CM, Tuon L, Stertz L, Vainzof M, Kapczinski F, Quevedo J (2009) Striatum brain-derived neurotrophic factor levels are decreased in dystrophin-deficient mice. Neurosci Lett 459:66\u201368","journal-title":"Neurosci Lett"},{"key":"1573_CR42","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1042\/CS20160044","volume":"131","author":"M Mitre","year":"2017","unstructured":"Mitre M, Mariga A, Chao MV (2017) Neurotrophin signalling: novel insights into mechanisms and pathophysiology. Clin Sci (Lond) 131:13\u201323","journal-title":"Clin Sci (Lond)"},{"key":"1573_CR43","doi-asserted-by":"crossref","first-page":"1472","DOI":"10.1177\/0883073815570154","volume":"30","author":"R Banihani","year":"2015","unstructured":"Banihani R, Smile S, Yoon G, Dupuis A, Mosleh M, Snider A (2015) Cognitive and neurobehavioral profile in boys with Duchenne muscular dystrophy. J Child Neurol 30:1472\u20131482","journal-title":"J Child Neurol"},{"key":"1573_CR44","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1002\/mus.23320","volume":"46","author":"M Rose","year":"2012","unstructured":"Rose M, Sadjadi R, Weinman J (2012) Muscle Study Group: role of disease severity, illness perceptions, and mood on quality of life in muscle disease. Muscle Nerve 46:351\u2013359","journal-title":"Muscle Nerve"},{"key":"1573_CR45","doi-asserted-by":"crossref","first-page":"1185","DOI":"10.1017\/S0033291705004812","volume":"35","author":"J Nuyen","year":"2005","unstructured":"Nuyen J, Volkers A, Verhaak P, Schellevis F, Groenewegen P, Van den Bos G (2005) Accuracy of diagnosing depression in primary care: the impact of chronic somatic and psychiatric co-morbidity. Psychol Med 35:1185\u20131195","journal-title":"Psychol Med"},{"key":"1573_CR46","doi-asserted-by":"crossref","first-page":"1242","DOI":"10.1016\/j.apmr.2015.02.012","volume":"96","author":"RF Pangalila","year":"2015","unstructured":"Pangalila RF, van den Bos GA, Bartels B, Bergen M, Stam HJ, Roebroeck ME (2015) Prevalence of fatigue, pain, and affective disorders in adults with Duchenne muscular dystrophy and their associations with quality of life. Arch Phys Med Rehabil 96:1242\u20131247","journal-title":"Arch Phys Med Rehabil"},{"key":"1573_CR47","doi-asserted-by":"crossref","first-page":"676","DOI":"10.1096\/fj.03-1024com","volume":"18","author":"MD Grounds","year":"2004","unstructured":"Grounds MD, Torrisi J (2004) Anti-TNFalpha (Remicade) therapy protects dystrophic skeletal muscle from necrosis. FASEB J 18:676\u2013682","journal-title":"FASEB J"},{"key":"1573_CR48","first-page":"304","volume":"34","author":"JCR Vellosa","year":"2013","unstructured":"Vellosa JCR, Parabocz GC, Manente FA, Ribas JT, Lima LW (2013) Altera\u00e7\u00f5es metab\u00f3licas e inflamat\u00f3rias em condi\u00e7\u00f5es de estresse oxidativo. Rev Ci\u00eanc Fram B\u00e1sica Apl 34:304\u2013312","journal-title":"Rev Ci\u00eanc Fram B\u00e1sica Apl"},{"key":"1573_CR49","doi-asserted-by":"crossref","first-page":"511","DOI":"10.1523\/JNEUROSCI.15-01-00511.1995","volume":"15","author":"J Alder","year":"1995","unstructured":"Alder J, Kanki H, Valtorta F, Greengard P, Poo MM (1995) Overexpression of synaptophysin enhances neurotransmitter secretion at Xenopus neuromuscular synapses. J Neurosci 15:511\u2013519","journal-title":"J Neurosci"},{"key":"1573_CR50","doi-asserted-by":"crossref","first-page":"469","DOI":"10.3389\/fnins.2015.00469","volume":"9","author":"J Lewerenz","year":"2015","unstructured":"Lewerenz J, Maher P (2015) Chronic glutamate toxicity in neurodegenerative diseases\u2014what is the evidence? Front Neurosci 9:469","journal-title":"Front Neurosci"},{"key":"1573_CR51","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1139\/Y09-058","volume":"88","author":"DG Allen","year":"2010","unstructured":"Allen DG, Gervasio OL, Yeung EW, Whitehead NP (2010) Calcium and the damage pathways in muscular dystrophy. Can J Physiol Pharmacol 88:83\u201391","journal-title":"Can J Physiol Pharmacol"},{"key":"1573_CR52","doi-asserted-by":"crossref","first-page":"8823","DOI":"10.3390\/molecules20058823","volume":"20","author":"TL van Westering","year":"2015","unstructured":"van Westering TL, Betts CA, Wood MJ (2015) Current understanding of molecular pathology and treatment of cardiomyopathy in Duchenne muscular dystrophy. Molecules 20:8823\u20138855","journal-title":"Molecules"},{"key":"1573_CR53","doi-asserted-by":"crossref","first-page":"7455","DOI":"10.1523\/JNEUROSCI.21-19-07455.2001","volume":"21","author":"D Schubert","year":"2001","unstructured":"Schubert D, Piasecki D (2001) Oxidative glutamate toxicity can be a component of the excitotoxicity cascade. J Neurosci 21:7455\u20137462","journal-title":"J Neurosci"}],"container-title":["Molecular Neurobiology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s12035-019-1573-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s12035-019-1573-7\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s12035-019-1573-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,5,8]],"date-time":"2020-05-08T19:33:09Z","timestamp":1588966389000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s12035-019-1573-7"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,5,10]]},"references-count":53,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2019,11]]}},"alternative-id":["1573"],"URL":"https:\/\/doi.org\/10.1007\/s12035-019-1573-7","relation":{},"ISSN":["0893-7648","1559-1182"],"issn-type":[{"value":"0893-7648","type":"print"},{"value":"1559-1182","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,5,10]]},"assertion":[{"value":"14 May 2018","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"20 March 2019","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"10 May 2019","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"All experimental procedures involving animals were performed in accordance with the NIH Guide for the Care and Use of Laboratory Animals. All protocols performed were approved by the ethics committee at UNISUL (protocol number 16.033.4.01.IV).","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with Ethical Standards"}},{"value":"The authors declare that they have no conflict of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of Interest"}}]}}