{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T19:21:27Z","timestamp":1792783287969,"version":"4.5.0"},"reference-count":138,"publisher":"Springer Science and Business Media LLC","issue":"10","license":[{"start":{"date-parts":[[2020,7,27]],"date-time":"2020-07-27T00:00:00Z","timestamp":1595808000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2020,7,27]],"date-time":"2020-07-27T00:00:00Z","timestamp":1595808000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"funder":[{"DOI":"10.13039\/501100002081","name":"Irish Research Council","doi-asserted-by":"publisher","award":["GOIPG\/2017\/1350"],"award-info":[{"award-number":["GOIPG\/2017\/1350"]}],"id":[{"id":"10.13039\/501100002081","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001602","name":"Science Foundation Ireland","doi-asserted-by":"crossref","award":["16\/RC\/3948"],"award-info":[{"award-number":["16\/RC\/3948"]}],"id":[{"id":"10.13039\/501100001602","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100001602","name":"Science Foundation Ireland","doi-asserted-by":"crossref","award":["SFI\/13\/IA\/1891"],"award-info":[{"award-number":["SFI\/13\/IA\/1891"]}],"id":[{"id":"10.13039\/501100001602","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100001602","name":"Science Foundation Ireland","doi-asserted-by":"crossref","award":["SFI\/14\/ADV\/RC2721"],"award-info":[{"award-number":["SFI\/14\/ADV\/RC2721"]}],"id":[{"id":"10.13039\/501100001602","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100000925","name":"National Health and Medical Research Council","doi-asserted-by":"publisher","award":["1084913"],"award-info":[{"award-number":["1084913"]}],"id":[{"id":"10.13039\/501100000925","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100018897","name":"Lions Medical Research Foundation","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100018897","id-type":"DOI","asserted-by":"crossref"}]},{"name":"Australian Research Training Program"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Mol Neurobiol"],"published-print":{"date-parts":[[2020,10]]},"DOI":"10.1007\/s12035-020-02018-w","type":"journal-article","created":{"date-parts":[[2020,7,27]],"date-time":"2020-07-27T06:02:48Z","timestamp":1595829768000},"page":"4322-4344","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":20,"title":["Temporally Altered miRNA Expression in a Piglet Model of Hypoxic Ischemic Brain Injury"],"prefix":"10.1007","volume":"57","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7704-3568","authenticated-orcid":false,"given":"Sophie","family":"Casey","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kate","family":"Goasdoue","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephanie M.","family":"Miller","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gary P.","family":"Brennan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gary","family":"Cowin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adam G.","family":"O\u2019Mahony","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopher","family":"Burke","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Boubou","family":"Hallberg","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Geraldine B.","family":"Boylan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aideen M.","family":"Sullivan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David C.","family":"Henshall","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gerard W.","family":"O\u2019Keeffe","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Catherine","family":"Mooney","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tracey","family":"Bjorkman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Deirdre M.","family":"Murray","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2020,7,27]]},"reference":[{"issue":"4","key":"2018_CR1","doi-asserted-by":"publisher","first-page":"397","DOI":"10.1001\/jamapediatrics.2014.3269","volume":"169","author":"M Douglas-Escobar","year":"2015","unstructured":"Douglas-Escobar M, Weiss MD (2015) Hypoxic-ischemic encephalopathy: a review for the clinician. JAMA Pediatr 169(4):397\u2013403. https:\/\/doi.org\/10.1001\/jamapediatrics.2014.3269","journal-title":"JAMA Pediatr"},{"issue":"6","key":"2018_CR2","doi-asserted-by":"publisher","first-page":"329","DOI":"10.1016\/j.earlhumdev.2010.05.010","volume":"86","author":"JJ Kurinczuk","year":"2010","unstructured":"Kurinczuk JJ, White-Koning M, Badawi N (2010) Epidemiology of neonatal encephalopathy and hypoxic\u2013ischaemic encephalopathy. Early Hum Dev 86(6):329\u2013338. https:\/\/doi.org\/10.1016\/j.earlhumdev.2010.05.010","journal-title":"Early Hum Dev"},{"issue":"3","key":"2018_CR3","doi-asserted-by":"publisher","first-page":"125","DOI":"10.1053\/j.nainr.2011.07.004","volume":"11","author":"KA Allen","year":"2011","unstructured":"Allen KA, Brandon DH (2011) Hypoxic ischemic encephalopathy: pathophysiology and experimental treatments. Newborn Infant Nurs Rev 11(3):125\u2013133. https:\/\/doi.org\/10.1053\/j.nainr.2011.07.004","journal-title":"Newborn Infant Nurs Rev"},{"issue":"1","key":"2018_CR4","doi-asserted-by":"publisher","first-page":"35","DOI":"10.1016\/j.jpeds.2012.06.042","volume":"162","author":"TL DuPont","year":"2013","unstructured":"DuPont TL, Chalak LF, Morriss MC, Burchfield PJ, Christie L, S\u00e1nchez PJ (2013) Short-term outcomes of newborns with perinatal acidemia who are not eligible for systemic hypothermia therapy. J Pediatr 162(1):35\u201341. https:\/\/doi.org\/10.1016\/j.jpeds.2012.06.042","journal-title":"J Pediatr"},{"issue":"2","key":"2018_CR5","doi-asserted-by":"publisher","first-page":"269","DOI":"10.1016\/j.jpeds.2015.04.060","volume":"167","author":"AM Looney","year":"2015","unstructured":"Looney AM, Walsh BH, Moloney G, Grenham S, Fagan A, O\u2019Keeffe GW, Clarke G, Cryan JF et al (2015) Downregulation of umbilical cord blood levels of miR-374a in neonatal hypoxic ischemic encephalopathy. J Pediatr 167(2):269\u2013273.e262. https:\/\/doi.org\/10.1016\/j.jpeds.2015.04.060","journal-title":"J Pediatr"},{"key":"2018_CR6","first-page":"0320","volume":"2007","author":"W McGuire","year":"2007","unstructured":"McGuire W (2007) Perinatal asphyxia. BMJ Clin Evid 2007:0320","journal-title":"BMJ Clin Evid"},{"issue":"6","key":"2018_CR7","doi-asserted-by":"publisher","first-page":"1004","DOI":"10.1542\/peds.100.6.1004","volume":"100","author":"RC Vannucci","year":"1997","unstructured":"Vannucci RC, Perlman JM (1997) Interventions for perinatal hypoxic-ischemic encephalopathy. Pediatrics 100(6):1004\u20131014","journal-title":"Pediatrics"},{"key":"2018_CR8","doi-asserted-by":"publisher","first-page":"198","DOI":"10.3389\/fneur.2015.00198","volume":"6","author":"JO Davidson","year":"2015","unstructured":"Davidson JO, Wassink G, van den Heuij LG, Bennet L, Gunn AJ (2015) Therapeutic hypothermia for neonatal hypoxic\u2013ischemic encephalopathy\u2009\u2013\u2009where to from here? Front Neurol 6:198. https:\/\/doi.org\/10.3389\/fneur.2015.00198","journal-title":"Front Neurol"},{"issue":"2","key":"2018_CR9","doi-asserted-by":"publisher","first-page":"154","DOI":"10.1016\/j.nurx.2006.01.007","volume":"3","author":"AJ Gunn","year":"2006","unstructured":"Gunn AJ, Thoresen M (2006) Hypothermic neuroprotection. NeuroRX 3(2):154\u2013169. https:\/\/doi.org\/10.1016\/j.nurx.2006.01.007","journal-title":"NeuroRX"},{"key":"2018_CR10","doi-asserted-by":"publisher","first-page":"40","DOI":"10.3389\/fnins.2014.00040","volume":"8","author":"G Wassink","year":"2014","unstructured":"Wassink G, Gunn ER, Drury PP, Bennet L, Gunn AJ (2014) The mechanisms and treatment of asphyxial encephalopathy. Front Neurosci 8:40. https:\/\/doi.org\/10.3389\/fnins.2014.00040","journal-title":"Front Neurosci"},{"issue":"3","key":"2018_CR11","doi-asserted-by":"publisher","first-page":"153","DOI":"10.1093\/pch\/16.3.153","volume":"16","author":"F Khurshid","year":"2011","unstructured":"Khurshid F, Lee K-S, McNamara PJ, Whyte H, Mak W (2011) Lessons learned during implementation of therapeutic hypothermia for neonatal hypoxic ischemic encephalopathy in a regional transport program in Ontario. Paediatr Child Health 16(3):153\u2013156","journal-title":"Paediatr Child Health"},{"issue":"1","key":"2018_CR12","doi-asserted-by":"publisher","first-page":"31","DOI":"10.1515\/revneuro-2016-0022","volume":"28","author":"L Huang","year":"2017","unstructured":"Huang L, Zhao F, Qu Y, Zhang L, Wang Y, Mu D (2017) Animal models of hypoxic-ischemic encephalopathy: optimal choices for the best outcomes. Rev Neurosci 28(1):31\u201343. https:\/\/doi.org\/10.1515\/revneuro-2016-0022","journal-title":"Rev Neurosci"},{"issue":"2","key":"2018_CR13","doi-asserted-by":"publisher","first-page":"156","DOI":"10.1002\/ana.23647","volume":"72","author":"JJ Volpe","year":"2012","unstructured":"Volpe JJ (2012) Neonatal encephalopathy: an inadequate term for hypoxic\u2013ischemic encephalopathy. Ann Neurol 72(2):156\u2013166. https:\/\/doi.org\/10.1002\/ana.23647","journal-title":"Ann Neurol"},{"issue":"1","key":"2018_CR14","doi-asserted-by":"publisher","first-page":"157","DOI":"10.1016\/j.neuroscience.2009.11.067","volume":"166","author":"ST Bjorkman","year":"2010","unstructured":"Bjorkman ST, Miller SM, Rose SE, Burke C, Colditz PB (2010) Seizures are associated with brain injury severity in a neonatal model of hypoxia-ischemia. Neuroscience 166(1):157\u2013167. https:\/\/doi.org\/10.1016\/j.neuroscience.2009.11.067","journal-title":"Neuroscience"},{"issue":"1","key":"2018_CR15","doi-asserted-by":"publisher","first-page":"110","DOI":"10.1016\/j.brainres.2006.04.119","volume":"1100","author":"ST Bj\u00f6rkman","year":"2006","unstructured":"Bj\u00f6rkman ST, Foster KA, O\u2019Driscoll SM, Healy GN, Lingwood BE, Burke C, Colditz PB (2006) Hypoxic\/ischemic models in newborn piglet: comparison of constant FiO2 versus variable FiO2 delivery. Brain Res 1100(1):110\u2013117. https:\/\/doi.org\/10.1016\/j.brainres.2006.04.119","journal-title":"Brain Res"},{"issue":"3","key":"2018_CR16","doi-asserted-by":"publisher","first-page":"455","DOI":"10.3171\/jns.2000.93.3.0455","volume":"93","author":"A-C Duhaime","year":"2000","unstructured":"Duhaime A-C, Margulies SS, Durham SR, O\u2019Rourke MM, Golden JA, Marwaha S, Raghupathi R (2000) Maturation-dependent response of the piglet brain to scaled cortical impact. J Neurosurg 93(3):455\u2013462","journal-title":"J Neurosurg"},{"issue":"2","key":"2018_CR17","doi-asserted-by":"publisher","first-page":"281","DOI":"10.1016\/S0092-8674(04)00045-5","volume":"116","author":"DP Bartel","year":"2004","unstructured":"Bartel DP (2004) MicroRNAs: genomics, biogenesis, mechanism, and function. Cell 116(2):281\u2013297. https:\/\/doi.org\/10.1016\/S0092-8674(04)00045-5","journal-title":"Cell"},{"key":"2018_CR18","doi-asserted-by":"publisher","first-page":"5","DOI":"10.1155\/2013\/350419","volume":"2013","author":"J Qiu","year":"2013","unstructured":"Qiu J, X-y Z, X-g Z, Cheng R, H-y L, Li Y (2013) Neuroprotective effects of microRNA-210 on hypoxic-ischemic encephalopathy. Biomed Res Int 2013:5\u20135. https:\/\/doi.org\/10.1155\/2013\/350419","journal-title":"Biomed Res Int"},{"issue":"7","key":"2018_CR19","doi-asserted-by":"publisher","first-page":"823","DOI":"10.1016\/S0092-8674(01)00616-X","volume":"107","author":"V Ambros","year":"2001","unstructured":"Ambros V (2001) microRNAs: tiny regulators with great potential. Cell 107(7):823\u2013826. https:\/\/doi.org\/10.1016\/S0092-8674(01)00616-X","journal-title":"Cell"},{"issue":"9","key":"2018_CR20","doi-asserted-by":"publisher","first-page":"790","DOI":"10.1016\/S0960-9822(03)00250-1","volume":"13","author":"P Xu","year":"2003","unstructured":"Xu P, Vernooy SY, Guo M, Hay BA (2003) The drosophila MicroRNA Mir-14 suppresses cell death and is required for normal fat metabolism. Curr Biol 13(9):790\u2013795. https:\/\/doi.org\/10.1016\/S0960-9822(03)00250-1","journal-title":"Curr Biol"},{"issue":"5","key":"2018_CR21","doi-asserted-by":"publisher","first-page":"1859","DOI":"10.1128\/MCB.01395-06","volume":"27","author":"R Kulshreshtha","year":"2007","unstructured":"Kulshreshtha R, Ferracin M, Wojcik SE, Garzon R, Alder H, Agosto-Perez FJ, Davuluri R, Liu C-G et al (2007) A microRNA signature of hypoxia. Mol Cell Biol 27(5):1859\u20131867. https:\/\/doi.org\/10.1128\/MCB.01395-06","journal-title":"Mol Cell Biol"},{"key":"2018_CR22","doi-asserted-by":"publisher","first-page":"129","DOI":"10.1007\/978-1-62703-453-1_10","volume":"1024","author":"L Moldovan","year":"2013","unstructured":"Moldovan L, Batte K, Wang Y, Wisler J, Piper M (2013) Analyzing the circulating microRNAs in exosomes\/extracellular vesicles from serum or plasma by qRT-PCR. Methods Mol Biol (Clifton, NJ) 1024:129\u2013145. https:\/\/doi.org\/10.1007\/978-1-62703-453-1_10","journal-title":"Methods Mol Biol (Clifton, NJ)"},{"issue":"40","key":"2018_CR23","doi-asserted-by":"publisher","first-page":"6206","DOI":"10.2174\/1381612823666170913164738","volume":"23","author":"J Matsumoto","year":"2017","unstructured":"Matsumoto J, Stewart T, Banks WA, Zhang J (2017) The transport mechanism of extracellular vesicles at the blood-brain barrier. Curr Pharm Des 23(40):6206\u20136214. https:\/\/doi.org\/10.2174\/1381612823666170913164738","journal-title":"Curr Pharm Des"},{"key":"2018_CR24","doi-asserted-by":"publisher","first-page":"282","DOI":"10.1016\/j.cca.2015.08.021","volume":"450","author":"H Lv","year":"2015","unstructured":"Lv H, Wang Q, Wu S, Yang L, Ren P, Yang Y, Gao J, Li L (2015) Neonatal hypoxic ischemic encephalopathy-related biomarkers in serum and cerebrospinal fluid. Clin Chim Acta 450:282\u2013297. https:\/\/doi.org\/10.1016\/j.cca.2015.08.021","journal-title":"Clin Chim Acta"},{"key":"2018_CR25","doi-asserted-by":"publisher","first-page":"202","DOI":"10.1016\/j.nbd.2016.02.011","volume":"89","author":"Q Ma","year":"2016","unstructured":"Ma Q, Dasgupta C, Li Y, Bajwa NM, Xiong F, Harding B, Hartman R, Zhang L (2016) Inhibition of microRNA-210 provides neuroprotection in hypoxic\u2013ischemic brain injury in neonatal rats. Neurobiol Dis 89:202\u2013212. https:\/\/doi.org\/10.1016\/j.nbd.2016.02.011","journal-title":"Neurobiol Dis"},{"issue":"4","key":"2018_CR26","doi-asserted-by":"publisher","first-page":"675","DOI":"10.1038\/jcbfm.2008.157","volume":"29","author":"A Dharap","year":"2009","unstructured":"Dharap A, Bowen K, Place R, Li L-C, Vemuganti R (2009) Transient focal ischemia induces extensive temporal changes in rat cerebral microRNAome. J Cereb Blood Flow Metab 29(4):675\u2013687. https:\/\/doi.org\/10.1038\/jcbfm.2008.157","journal-title":"J Cereb Blood Flow Metab"},{"issue":"2","key":"2018_CR27","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0014724","volume":"6","author":"M Ziu","year":"2011","unstructured":"Ziu M, Fletcher L, Rana S, Jimenez DF, Digicaylioglu M (2011) Temporal differences in microRNA expression patterns in astrocytes and neurons after ischemic injury. PLoS One 6(2):e14724. https:\/\/doi.org\/10.1371\/journal.pone.0014724","journal-title":"PLoS One"},{"issue":"20","key":"2018_CR28","doi-asserted-by":"publisher","first-page":"3365","DOI":"10.1093\/bioinformatics\/btv380","volume":"31","author":"DM Vitsios","year":"2015","unstructured":"Vitsios DM, Enright AJ (2015) Chimira: analysis of small RNA sequencing data and microRNA modifications. Bioinformatics 31(20):3365\u20133367","journal-title":"Bioinformatics"},{"issue":"D1","key":"2018_CR29","doi-asserted-by":"publisher","first-page":"D754","DOI":"10.1093\/nar\/gkx1098","volume":"46","author":"DR Zerbino","year":"2018","unstructured":"Zerbino DR, Achuthan P, Akanni W, Amode MR, Barrell D, Bhai J, Billis K, Cummins C et al (2018) Ensembl 2018. Nucleic Acids Res 46(D1):D754\u2013D761. https:\/\/doi.org\/10.1093\/nar\/gkx1098","journal-title":"Nucleic Acids Res"},{"key":"2018_CR30","doi-asserted-by":"publisher","first-page":"194","DOI":"10.1016\/j.parkreldis.2019.04.008","volume":"64","author":"SR Goulding","year":"2019","unstructured":"Goulding SR, Sullivan AM, O\u2019Keeffe GW, Collins LM (2019) Gene co-expression analysis of the human substantia nigra identifies BMP2 as a neurotrophic factor that can promote neurite growth in cells overexpressing wild-type or A53T \u03b1-synuclein. Parkinsonism Relat Disord 64:194\u2013201. https:\/\/doi.org\/10.1016\/j.parkreldis.2019.04.008","journal-title":"Parkinsonism Relat Disord"},{"issue":"2","key":"2018_CR31","doi-asserted-by":"publisher","first-page":"191","DOI":"10.1530\/rep.1.01074","volume":"132","author":"PG Knight","year":"2006","unstructured":"Knight PG, Glister C (2006) TGF-\u03b2 superfamily members and ovarian follicle development. Reproduction 132(2):191\u2013206","journal-title":"Reproduction"},{"key":"2018_CR32","doi-asserted-by":"publisher","unstructured":"Li B, Dasgupta C, Huang L, Meng X, Zhang L (2019) MiRNA-210 induces microglial activation and regulates microglia-mediated neuroinflammation in neonatal hypoxic-ischemic encephalopathy. Cell Mol Immunol. https:\/\/doi.org\/10.1038\/s41423-019-0257-6","DOI":"10.1038\/s41423-019-0257-6"},{"key":"2018_CR33","doi-asserted-by":"publisher","first-page":"117664","DOI":"10.1016\/j.lfs.2020.117664","volume":"252","author":"Z Chen","year":"2020","unstructured":"Chen Z, Hu Y, Lu R, Ge M, Zhang L (2020) MicroRNA-374a-5p inhibits neuroinflammation in neonatal hypoxic-ischemic encephalopathy via regulating NLRP3 inflammasome targeted Smad6. Life Sci 252:117664. https:\/\/doi.org\/10.1016\/j.lfs.2020.117664","journal-title":"Life Sci"},{"issue":"1","key":"2018_CR34","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1186\/1758-907X-3-1","volume":"3","author":"J Stenvang","year":"2012","unstructured":"Stenvang J, Petri A, Lindow M, Obad S, Kauppinen S (2012) Inhibition of microRNA function by antimiR oligonucleotides. Silence 3(1):1. https:\/\/doi.org\/10.1186\/1758-907X-3-1","journal-title":"Silence"},{"key":"2018_CR35","doi-asserted-by":"publisher","first-page":"20","DOI":"10.1016\/j.freeradbiomed.2013.05.022","volume":"64","author":"S Nallamshetty","year":"2013","unstructured":"Nallamshetty S, Chan SY, Loscalzo J (2013) Hypoxia: a master regulator of microRNA biogenesis and activity. Free Radic Biol Med 64:20\u201330. https:\/\/doi.org\/10.1016\/j.freeradbiomed.2013.05.022","journal-title":"Free Radic Biol Med"},{"issue":"12","key":"2018_CR36","doi-asserted-by":"publisher","first-page":"2078","DOI":"10.3390\/ijms17122078","volume":"17","author":"M Zhao","year":"2016","unstructured":"Zhao M, Zhu P, Fujino M, Zhuang J, Guo H, Sheikh I, Zhao L, Li X-K (2016) Oxidative stress in hypoxic-ischemic encephalopathy: molecular mechanisms and therapeutic strategies. Int J Mol Sci 17(12):2078. https:\/\/doi.org\/10.3390\/ijms17122078","journal-title":"Int J Mol Sci"},{"issue":"20","key":"2018_CR37","doi-asserted-by":"publisher","first-page":"3059","DOI":"10.1016\/j.yexcr.2013.07.031","volume":"319","author":"M Li","year":"2013","unstructured":"Li M, Fu W, Wo L, Shu X, Liu F, Li C (2013) miR-128 and its target genes in tumorigenesis and metastasis. Exp Cell Res 319(20):3059\u20133064. https:\/\/doi.org\/10.1016\/j.yexcr.2013.07.031","journal-title":"Exp Cell Res"},{"key":"2018_CR38","doi-asserted-by":"publisher","first-page":"e542","DOI":"10.1038\/cddis.2013.46","volume":"4","author":"YK Adlakha","year":"2013","unstructured":"Adlakha YK, Saini N (2013) miR-128 exerts pro-apoptotic effect in a p53 transcription-dependent and -independent manner via PUMA-Bak axis. Cell Death Dis 4:e542. https:\/\/doi.org\/10.1038\/cddis.2013.46 https:\/\/www.nature.com\/articles\/cddis201346#supplementary-information","journal-title":"Cell Death Dis"},{"issue":"12","key":"2018_CR39","doi-asserted-by":"publisher","first-page":"4276","DOI":"10.1096\/fj.09-134965","volume":"23","author":"C Evangelisti","year":"2009","unstructured":"Evangelisti C, Florian MC, Massimi I, Dominici C, Giannini G, Galardi S, Bu\u00e8 MC, Massalini S et al (2009) MiR-128 up-regulation inhibits Reelin and DCX expression and reduces neuroblastoma cell motility and invasiveness. FASEB J 23(12):4276\u20134287. https:\/\/doi.org\/10.1096\/fj.09-134965","journal-title":"FASEB J"},{"issue":"2","key":"2018_CR40","doi-asserted-by":"publisher","first-page":"298","DOI":"10.1074\/mcp.M900159-MCP200","volume":"9","author":"AP Khan","year":"2010","unstructured":"Khan AP, Poisson LM, Bhat VB, Fermin D, Zhao R, Kalyana-Sundaram S, Michailidis G, Nesvizhskii AI et al (2010) Quantitative proteomic profiling of prostate cancer reveals a role for miR-128 in prostate cancer. Mol Cell Proteomics 9(2):298\u2013312","journal-title":"Mol Cell Proteomics"},{"issue":"6","key":"2018_CR41","first-page":"575","volume":"4","author":"D Zheng","year":"2011","unstructured":"Zheng D, Haddadin S, Wang Y, Gu L-Q, Perry MC, Freter CE, Wang MX (2011) Plasma microRNAs as novel biomarkers for early detection of lung cancer. Int J Clin Exp Pathol 4(6):575\u2013586","journal-title":"Int J Clin Exp Pathol"},{"issue":"50","key":"2018_CR42","doi-asserted-by":"publisher","first-page":"19971","DOI":"10.1073\/pnas.0709313104","volume":"104","author":"S Mi","year":"2007","unstructured":"Mi S, Lu J, Sun M, Li Z, Zhang H, Neilly MB, Wang Y, Qian Z et al (2007) MicroRNA expression signatures accurately discriminate acute lymphoblastic leukemia from acute myeloid leukemia. Proc Natl Acad Sci 104(50):19971\u201319976","journal-title":"Proc Natl Acad Sci"},{"key":"2018_CR43","doi-asserted-by":"publisher","first-page":"63","DOI":"10.1016\/j.biopha.2016.03.040","volume":"81","author":"G-C Ding","year":"2016","unstructured":"Ding G-C, Chen M, Wang Y-X, Rui C, Xu W, Ding H-J, Shi Z-H (2016) MicroRNA-128a-induced apoptosis in HTR-8\/SVneo trophoblast cells contributes to pre-eclampsia. Biomed Pharmacother 81:63\u201370. https:\/\/doi.org\/10.1016\/j.biopha.2016.03.040","journal-title":"Biomed Pharmacother"},{"issue":"1","key":"2018_CR44","doi-asserted-by":"publisher","first-page":"3140","DOI":"10.1038\/s41598-017-02694-0","volume":"7","author":"C De Santi","year":"2017","unstructured":"De Santi C, Melaiu O, Bonotti A, Cascione L, Di Leva G, Foddis R, Cristaudo A, Lucchi M et al (2017) Deregulation of miRNAs in malignant pleural mesothelioma is associated with prognosis and suggests an alteration of cell metabolism. Sci Rep 7(1):3140. https:\/\/doi.org\/10.1038\/s41598-017-02694-0","journal-title":"Sci Rep"},{"issue":"1","key":"2018_CR45","first-page":"467","volume":"15","author":"B Hu","year":"2018","unstructured":"Hu B, Tang WG, Fan J, Xu Y, Sun HX (2018) Differentially expressed miRNAs in hepatocellular carcinoma cells under hypoxic conditions are associated with transcription and phosphorylation. Oncol Lett 15(1):467\u2013474","journal-title":"Oncol Lett"},{"issue":"8","key":"2018_CR46","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0043812","volume":"7","author":"T Chiyomaru","year":"2012","unstructured":"Chiyomaru T, Yamamura S, Zaman MS, Majid S, Deng G, Shahryari V, Saini S, Hirata H et al (2012) Genistein suppresses prostate cancer growth through inhibition of oncogenic MicroRNA-151. PLoS One 7(8):e43812. https:\/\/doi.org\/10.1371\/journal.pone.0043812","journal-title":"PLoS One"},{"key":"2018_CR47","doi-asserted-by":"publisher","first-page":"17743","DOI":"10.1038\/srep17743","volume":"5","author":"R Zhou","year":"2015","unstructured":"Zhou R, Wang R, Qin Y, Ji J, Xu M, Wu W, Chen M, Wu D et al (2015) Mitochondria-related miR-151a-5p reduces cellular ATP production by targeting CYTB in asthenozoospermia. Sci Rep 5:17743. https:\/\/doi.org\/10.1038\/srep17743https:\/\/www.nature.com\/articles\/srep17743#supplementary-information","journal-title":"Sci Rep"},{"issue":"1","key":"2018_CR48","doi-asserted-by":"publisher","first-page":"40","DOI":"10.1186\/2040-2392-5-40","volume":"5","author":"MM Vasu","year":"2014","unstructured":"Vasu MM, Anitha A, Thanseem I, Suzuki K, Yamada K, Takahashi T, Wakuda T, Iwata K et al (2014) Serum microRNA profiles in children with autism. Mol Autism 5(1):40","journal-title":"Mol Autism"},{"issue":"7","key":"2018_CR49","doi-asserted-by":"publisher","first-page":"397","DOI":"10.1002\/ddr.21277","volume":"76","author":"S Gupta","year":"2015","unstructured":"Gupta S, Verma S, Mantri S, Berman NE, Sandhir R (2015) Targeting microRNAs in prevention and treatment of neurodegenerative disorders. Drug Dev Res 76(7):397\u2013418","journal-title":"Drug Dev Res"},{"key":"2018_CR50","doi-asserted-by":"publisher","first-page":"3657","DOI":"10.1007\/s12035-018-1321-4","volume":"56","author":"AM Looney","year":"2018","unstructured":"Looney AM, O\u2019Sullivan MP, Ahearne CE, Finder M, Felderhoff-Mueser U, Boylan GB, Hallberg B, Murray DM (2018) Altered expression of umbilical cord blood levels of miR-181b and its downstream target mUCH-L1 in infants with moderate and severe neonatal hypoxic-ischaemic encephalopathy. Mol Neurobiol 56:3657\u20133663. https:\/\/doi.org\/10.1007\/s12035-018-1321-4","journal-title":"Mol Neurobiol"},{"key":"2018_CR51","doi-asserted-by":"publisher","first-page":"333","DOI":"10.1001\/jamaneurol.2018.4182","volume":"76","author":"M O\u2019Sullivan","year":"2018","unstructured":"O\u2019Sullivan M, Looney A, Moloney GM et al (2018) Validation of altered umbilical cord blood microrna expression in neonatal hypoxic-ischemic encephalopathy. JAMA Neurol 76:333\u2013341. https:\/\/doi.org\/10.1001\/jamaneurol.2018.4182","journal-title":"JAMA Neurol"},{"key":"2018_CR52","doi-asserted-by":"publisher","first-page":"185","DOI":"10.1016\/j.brainres.2008.07.085","volume":"1236","author":"L Shi","year":"2008","unstructured":"Shi L, Cheng Z, Zhang J, Li R, Zhao P, Fu Z, You Y (2008) hsa-mir-181a and hsa-mir-181b function as tumor suppressors in human glioma cells. Brain Res 1236:185\u2013193. https:\/\/doi.org\/10.1016\/j.brainres.2008.07.085","journal-title":"Brain Res"},{"issue":"10","key":"2018_CR53","doi-asserted-by":"publisher","first-page":"1349","DOI":"10.1002\/jnr.23255","volume":"91","author":"Z Peng","year":"2013","unstructured":"Peng Z, Li J, Li Y, Yang X, Feng S, Han S, Li J (2013) Downregulation of miR-181b in mouse brain following ischemic stroke induces neuroprotection against ischemic injury through targeting heat shock protein A5 and ubiquitin carboxyl-terminal hydrolase isozyme L1. J Neurosci Res 91(10):1349\u20131362","journal-title":"J Neurosci Res"},{"key":"2018_CR54","doi-asserted-by":"publisher","first-page":"392","DOI":"10.1016\/j.brainresbull.2018.05.015","volume":"140","author":"H Zhang","year":"2018","unstructured":"Zhang H, Zhong K, Lu M, Mei Y, Tan E, Sun X, Tan W (2018) Neuroprotective effects of isosteviol sodium through increasing CYLD by the downregulation of miRNA-181b. Brain Res Bull 140:392\u2013401. https:\/\/doi.org\/10.1016\/j.brainresbull.2018.05.015","journal-title":"Brain Res Bull"},{"issue":"11","key":"2018_CR55","first-page":"7672","volume":"7","author":"D Li","year":"2014","unstructured":"Li D, Jian W, Wei C, Song H, Gu Y, Luo Y, Fang L (2014) Down-regulation of miR-181b promotes apoptosis by targeting CYLD in thyroid papillary cancer. Int J Clin Exp Pathol 7(11):7672\u20137680","journal-title":"Int J Clin Exp Pathol"},{"issue":"1","key":"2018_CR56","doi-asserted-by":"publisher","DOI":"10.1002\/brb3.835","volume":"8","author":"Z Wang","year":"2018","unstructured":"Wang Z, Liu Y, Shao M, Wang D, Zhang Y (2018) Combined prediction of miR-210 and miR-374a for severity and prognosis of hypoxic-ischemic encephalopathy. Brain Behav 8(1):e00835. https:\/\/doi.org\/10.1002\/brb3.835","journal-title":"Brain Behav"},{"issue":"2","key":"2018_CR57","doi-asserted-by":"publisher","first-page":"133","DOI":"10.1159\/000449032","volume":"111","author":"HT Garberg","year":"2017","unstructured":"Garberg HT, Huun MU, Baumbusch LO, \u00c5segg-Atneosen M, Solberg R, Saugstad OD (2017) Temporal profile of circulating microRNAs after global hypoxia-ischemia in newborn piglets. Neonatology 111(2):133\u2013139","journal-title":"Neonatology"},{"key":"2018_CR58","doi-asserted-by":"publisher","first-page":"55","DOI":"10.1016\/j.neuropharm.2018.11.041","volume":"149","author":"V Ponnusamy","year":"2019","unstructured":"Ponnusamy V, Yip PK (2019) The role of microRNAs in newborn brain development and hypoxic ischaemic encephalopathy. Neuropharmacology 149:55\u201365. https:\/\/doi.org\/10.1016\/j.neuropharm.2018.11.041","journal-title":"Neuropharmacology"},{"issue":"11","key":"2018_CR59","doi-asserted-by":"publisher","first-page":"1749","DOI":"10.1038\/cdd.2016.64","volume":"23","author":"JR Gomes","year":"2016","unstructured":"Gomes JR, Nogueira RS, Vieira M, Santos SD, Ferraz-Nogueira JP, Relvas JB, Saraiva MJ (2016) Transthyretin provides trophic support via megalin by promoting neurite outgrowth and neuroprotection in cerebral ischemia. Cell Death Differ 23(11):1749\u20131764. https:\/\/doi.org\/10.1038\/cdd.2016.64","journal-title":"Cell Death Differ"},{"issue":"4","key":"2018_CR60","doi-asserted-by":"publisher","first-page":"775","DOI":"10.1016\/j.bbrc.2017.02.130","volume":"485","author":"W Zhao","year":"2017","unstructured":"Zhao W, Yan J, Gao L, Zhao J, Zhao C, Gao C, Luo X, Zhu X (2017) Cdk5 is required for the neuroprotective effect of transforming growth factor-\u03b21 against cerebral ischemia-reperfusion. Biochem Biophys Res Commun 485(4):775\u2013781. https:\/\/doi.org\/10.1016\/j.bbrc.2017.02.130","journal-title":"Biochem Biophys Res Commun"},{"issue":"2","key":"2018_CR61","doi-asserted-by":"publisher","first-page":"321","DOI":"10.1016\/j.neuroscience.2004.11.015","volume":"131","author":"CM O\u2019Driscoll","year":"2005","unstructured":"O\u2019Driscoll CM, Gorman AM (2005) Hypoxia induces neurite outgrowth in PC12 cells that is mediated through adenosine A2A receptors. Neuroscience 131(2):321\u2013329. https:\/\/doi.org\/10.1016\/j.neuroscience.2004.11.015","journal-title":"Neuroscience"},{"issue":"1","key":"2018_CR62","doi-asserted-by":"publisher","first-page":"147","DOI":"10.1016\/j.cell.2007.03.008","volume":"129","author":"Q-J Li","year":"2007","unstructured":"Li Q-J, Chau J, Ebert PJR, Sylvester G, Min H, Liu G, Braich R, Manoharan M et al (2007) miR-181a is an intrinsic modulator of T cell sensitivity and selection. Cell 129(1):147\u2013161. https:\/\/doi.org\/10.1016\/j.cell.2007.03.008","journal-title":"Cell"},{"issue":"1","key":"2018_CR63","doi-asserted-by":"publisher","first-page":"90","DOI":"10.2174\/138945013804806424","volume":"14","author":"Y-B Ouyang","year":"2013","unstructured":"Ouyang Y-B, Stary CM, Yang G-Y, Giffard R (2013) microRNAs: innovative targets for cerebral ischemia and stroke. Curr Drug Targets 14(1):90\u2013101","journal-title":"Curr Drug Targets"},{"issue":"2","key":"2018_CR64","doi-asserted-by":"publisher","first-page":"233","DOI":"10.1007\/s11064-013-1209-7","volume":"39","author":"H Kong","year":"2014","unstructured":"Kong H, Omran A, Ashhab MU, Gan N, Peng J, He F, Wu L, Deng X et al (2014) Changes in microglial inflammation-related and brain-enriched microRNAs expressions in response to in vitro oxygen\u2013glucose deprivation. Neurochem Res 39(2):233\u2013243. https:\/\/doi.org\/10.1007\/s11064-013-1209-7","journal-title":"Neurochem Res"},{"issue":"1","key":"2018_CR65","doi-asserted-by":"publisher","first-page":"115","DOI":"10.1002\/dvdy.20323","volume":"233","author":"K-Y Choi","year":"2005","unstructured":"Choi K-Y, Kim H-J, Lee M-H, Kwon T-G, Nah H-D, Furuichi T, Komori T, Nam S-H et al (2005) Runx2 regulates FGF2-induced Bmp2 expression during cranial bone development. Dev Dyn 233(1):115\u2013121. https:\/\/doi.org\/10.1002\/dvdy.20323","journal-title":"Dev Dyn"},{"key":"2018_CR66","doi-asserted-by":"publisher","first-page":"16009","DOI":"10.1038\/boneres.2016.9","volume":"4","author":"M Wu","year":"2016","unstructured":"Wu M, Chen G, Li Y-P (2016) TGF-\u03b2 and BMP signaling in osteoblast, skeletal development, and bone formation, homeostasis and disease. Bone Res 4:16009. https:\/\/doi.org\/10.1038\/boneres.2016.9","journal-title":"Bone Res"},{"issue":"6","key":"2018_CR67","doi-asserted-by":"publisher","first-page":"787","DOI":"10.1210\/er.2002-0003","volume":"23","author":"H Chang","year":"2002","unstructured":"Chang H, Brown CW, Matzuk MM (2002) Genetic analysis of the mammalian transforming growth factor-\u03b2 superfamily. Endocr Rev 23(6):787\u2013823. https:\/\/doi.org\/10.1210\/er.2002-0003","journal-title":"Endocr Rev"},{"issue":"1","key":"2018_CR68","doi-asserted-by":"publisher","first-page":"87","DOI":"10.1016\/j.gendis.2014.07.005","volume":"1","author":"RN Wang","year":"2014","unstructured":"Wang RN, Green J, Wang Z, Deng Y, Qiao M, Peabody M, Zhang Q, Ye J et al (2014) Bone morphogenetic protein (BMP) signaling in development and human diseases. Genes Dis 1(1):87\u2013105. https:\/\/doi.org\/10.1016\/j.gendis.2014.07.005","journal-title":"Genes Dis"},{"key":"2018_CR69","doi-asserted-by":"publisher","first-page":"46","DOI":"10.1016\/j.expneurol.2014.08.005","volume":"268","author":"E Sun","year":"2015","unstructured":"Sun E, Shi Y (2015) MicroRNAs: Small molecules with big roles in neurodevelopment and diseases. Exp Neurol 268:46\u201353. https:\/\/doi.org\/10.1016\/j.expneurol.2014.08.005","journal-title":"Exp Neurol"},{"issue":"6","key":"2018_CR70","doi-asserted-by":"publisher","first-page":"308","DOI":"10.5483\/bmbrep.2017.50.6.059","volume":"50","author":"M-J Kim","year":"2017","unstructured":"Kim M-J, Park SY, Chang HR, Jung EY, Munkhjargal A, Lim J-S, Lee M-S, Kim Y (2017) Clinical significance linked to functional defects in bone morphogenetic protein type 2 receptor, BMPR2. BMB Rep 50(6):308\u2013317. https:\/\/doi.org\/10.5483\/bmbrep.2017.50.6.059","journal-title":"BMB Rep"},{"issue":"1","key":"2018_CR71","doi-asserted-by":"publisher","first-page":"249","DOI":"10.1006\/dbio.2000.9670","volume":"221","author":"H Beppu","year":"2000","unstructured":"Beppu H, Kawabata M, Hamamoto T, Chytil A, Minowa O, Noda T, Miyazono K (2000) BMP type II receptor is required for gastrulation and early development of mouse embryos. Dev Biol 221(1):249\u2013258. https:\/\/doi.org\/10.1006\/dbio.2000.9670","journal-title":"Dev Biol"},{"issue":"2","key":"2018_CR72","doi-asserted-by":"publisher","first-page":"357","DOI":"10.1161\/STROKEAHA.109.565523","volume":"41","author":"J Samanta","year":"2010","unstructured":"Samanta J, Alden T, Gobeske K, Kan L, Kessler John A (2010) Noggin protects against ischemic brain injury in rodents. Stroke 41(2):357\u2013362. https:\/\/doi.org\/10.1161\/STROKEAHA.109.565523","journal-title":"Stroke"},{"issue":"12","key":"2018_CR73","doi-asserted-by":"publisher","first-page":"1819","DOI":"10.1016\/j.bbamcr.2009.09.012","volume":"1793","author":"Z Liu","year":"2009","unstructured":"Liu Z, Shen J, Pu K, Katus HA, Pl\u00f6ger F, Tiefenbacher CP, Chen X, Braun T (2009) GDF5 and BMP2 inhibit apoptosis via activation of BMPR2 and subsequent stabilization of XIAP. Biochim Biophysi Acta (BBA) Mol Cell Res 1793(12):1819\u20131827. https:\/\/doi.org\/10.1016\/j.bbamcr.2009.09.012","journal-title":"Biochim Biophysi Acta (BBA) Mol Cell Res"},{"key":"2018_CR74","doi-asserted-by":"publisher","first-page":"1702","DOI":"10.1038\/cdd.2011.28","volume":"18","author":"H Zhang","year":"2011","unstructured":"Zhang H, Li Y, Huang Q, Ren X, Hu H, Sheng H, Lai M (2011) MiR-148a promotes apoptosis by targeting Bcl-2 in colorectal cancer. Cell Death Differ 18:1702\u20131710. https:\/\/doi.org\/10.1038\/cdd.2011.28","journal-title":"Cell Death Differ"},{"issue":"8","key":"2018_CR75","first-page":"4645","volume":"7","author":"LJ Yang","year":"2014","unstructured":"Yang LJ, Ma DQ, Cui H (2014) Proteomic analysis of immature rat pups brain in response to hypoxia and ischemia challenge. Int J Clin Exp Pathol 7(8):4645\u20134660","journal-title":"Int J Clin Exp Pathol"},{"issue":"3","key":"2018_CR76","doi-asserted-by":"publisher","first-page":"1427","DOI":"10.1016\/0006-291X(91)91732-R","volume":"179","author":"AG DiLella","year":"1991","unstructured":"DiLella AG (1991) Chromosomal assignment of the human immunophilin FKBP-12 gene. Biochem Biophys Res Commun 179(3):1427\u20131433. https:\/\/doi.org\/10.1016\/0006-291X(91)91732-R","journal-title":"Biochem Biophys Res Commun"},{"key":"2018_CR77","doi-asserted-by":"publisher","first-page":"109","DOI":"10.1186\/1465-9921-6-109","volume":"6","author":"G Kwapiszewska","year":"2005","unstructured":"Kwapiszewska G, Wilhelm J, Wolff S, Laumanns I, Koenig IR, Ziegler A, Seeger W, Bohle RM et al (2005) Expression profiling of laser-microdissected intrapulmonary arteries in hypoxia-induced pulmonary hypertension. Respir Res 6:109. https:\/\/doi.org\/10.1186\/1465-9921-6-109","journal-title":"Respir Res"},{"issue":"2","key":"2018_CR78","doi-asserted-by":"publisher","first-page":"167","DOI":"10.3892\/br.2012.48","volume":"1","author":"A Chen","year":"2013","unstructured":"Chen A, Xiong L-J, Tong Y, Mao M (2013) The neuroprotective roles of BDNF in hypoxic ischemic brain injury. Biomed Rep 1(2):167\u2013176","journal-title":"Biomed Rep"},{"key":"2018_CR79","doi-asserted-by":"publisher","first-page":"8","DOI":"10.1016\/j.ijdevneu.2014.06.005","volume":"37","author":"M Dhobale","year":"2014","unstructured":"Dhobale M (2014) Neurotrophins: role in adverse pregnancy outcome. Int J Dev Neurosci 37:8\u201314. https:\/\/doi.org\/10.1016\/j.ijdevneu.2014.06.005","journal-title":"Int J Dev Neurosci"},{"issue":"10","key":"2018_CR80","doi-asserted-by":"publisher","first-page":"757","DOI":"10.1136\/adc.48.10.757","volume":"48","author":"J Dobbing","year":"1973","unstructured":"Dobbing J, Sands J (1973) Quantitative growth and development of human brain. Arch Dis Child 48(10):757\u2013767","journal-title":"Arch Dis Child"},{"issue":"3","key":"2018_CR81","doi-asserted-by":"publisher","first-page":"113","DOI":"10.1055\/s-2000-9293","volume":"17","author":"RC Vannucci","year":"2000","unstructured":"Vannucci RC (2000) Hypoxic-ischemic encephalopathy. Am J Perinatol 17(3):113\u2013120. https:\/\/doi.org\/10.1055\/s-2000-9293","journal-title":"Am J Perinatol"},{"key":"2018_CR82","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1155\/2011\/609813","volume":"2011","author":"MC Lai","year":"2011","unstructured":"Lai MC, Yang SN (2011) Perinatal hypoxic-ischemic encephalopathy. J Biomed Biotechnol 2011:1\u20136. https:\/\/doi.org\/10.1155\/2011\/609813","journal-title":"J Biomed Biotechnol"},{"key":"2018_CR83","doi-asserted-by":"publisher","first-page":"e382","DOI":"10.1542\/peds.2009-1046","volume":"125","author":"S Thayyil","year":"2010","unstructured":"Thayyil S, Chandrasekaran M, Taylor A, Bainbridge A, Cady EB, Chong WKK, Murad S, Omar RZ et al (2010) Cerebral magnetic resonance biomarkers in neonatal encephalopathy: a meta-analysis. Pediatrics 125:e382\u2013e395","journal-title":"Pediatrics"},{"issue":"1","key":"2018_CR84","doi-asserted-by":"publisher","first-page":"37","DOI":"10.2174\/157339631001140408120613","volume":"10","author":"NJ Robertson","year":"2014","unstructured":"Robertson NJ, Thayyil S, Cady EB, Raivich G (2014) Magnetic resonance spectroscopy biomarkers in term perinatal asphyxial encephalopathy: from neuropathological correlates to future clinical applications. Curr Pediatr Rev 10(1):37\u201347","journal-title":"Curr Pediatr Rev"},{"issue":"2","key":"2018_CR85","doi-asserted-by":"publisher","first-page":"76","DOI":"10.1017\/S0012162299000171","volume":"41","author":"JD Hanrahan","year":"1999","unstructured":"Hanrahan JD, Cox IJ, Azzopardi D, Cowan FM, Sargentoni J, Bell JD, Bryant DJ, Edwards AD (1999) Relation between proton magnetic resonance spectroscopy within 18 hours of birth asphyxia and neurodevelopment at 1 year of age. Dev Med Child Neurol 41(2):76\u201382. https:\/\/doi.org\/10.1017\/S0012162299000171","journal-title":"Dev Med Child Neurol"},{"issue":"10","key":"2018_CR86","doi-asserted-by":"publisher","first-page":"835","DOI":"10.1016\/j.braindev.2009.11.008","volume":"32","author":"G Ancora","year":"2010","unstructured":"Ancora G, Soffritti S, Lodi R, Tonon C, Grandi S, Locatelli C, Nardi L, Bisacchi N et al (2010) A combined a-EEG and MR spectroscopy study in term newborns with hypoxic\u2013ischemic encephalopathy. Brain and Development 32(10):835\u2013842. https:\/\/doi.org\/10.1016\/j.braindev.2009.11.008","journal-title":"Brain and Development"},{"issue":"4","key":"2018_CR87","doi-asserted-by":"publisher","first-page":"392","DOI":"10.1001\/jama.2013.284664","volume":"311","author":"NA Schultz","year":"2014","unstructured":"Schultz NA, Dehlendorff C, Jensen BV, Bjerregaard JK, Nielsen KR, Bojesen SE, Calatayud D, Nielsen SE et al (2014) Microrna biomarkers in whole blood for detection of pancreatic cancer. JAMA 311(4):392\u2013404. https:\/\/doi.org\/10.1001\/jama.2013.284664","journal-title":"JAMA"},{"issue":"9","key":"2018_CR88","doi-asserted-by":"publisher","first-page":"e46045","DOI":"10.1371\/journal.pone.0046045","volume":"7","author":"SK Patnaik","year":"2012","unstructured":"Patnaik SK, Yendamuri S, Kannisto E, Kucharczuk JC, Singhal S, Vachani A (2012) MicroRNA expression profiles of whole blood in lung adenocarcinoma. PLoS One 7(9):e46045. https:\/\/doi.org\/10.1371\/journal.pone.0046045","journal-title":"PLoS One"},{"key":"2018_CR89","doi-asserted-by":"publisher","first-page":"80","DOI":"10.1016\/j.earlhumdev.2018.02.007","volume":"120","author":"JM Conway","year":"2018","unstructured":"Conway JM, Walsh BH, Boylan GB, Murray DM (2018) Mild hypoxic ischaemic encephalopathy and long term neurodevelopmental outcome - a systematic review. Early Hum Dev 120:80\u201387. https:\/\/doi.org\/10.1016\/j.earlhumdev.2018.02.007","journal-title":"Early Hum Dev"},{"issue":"1","key":"2018_CR90","doi-asserted-by":"publisher","first-page":"474","DOI":"10.1186\/1471-2164-15-474","volume":"15","author":"P Leidinger","year":"2014","unstructured":"Leidinger P, Backes C, Meder B, Meese E, Keller A (2014) The human miRNA repertoire of different blood compounds. BMC Genomics 15(1):474. https:\/\/doi.org\/10.1186\/1471-2164-15-474","journal-title":"BMC Genomics"},{"key":"2018_CR91","doi-asserted-by":"publisher","first-page":"41127","DOI":"10.1038\/srep41127","volume":"7","author":"M Mas\u00e8","year":"2017","unstructured":"Mas\u00e8 M, Grasso M, Avogaro L, D\u2019Amato E, Tessarolo F, Graffigna A, Denti MA, Ravelli F (2017) Selection of reference genes is critical for miRNA expression analysis in human cardiac tissue. A focus on atrial fibrillation. Sci Rep 7:41127. https:\/\/doi.org\/10.1038\/srep41127 https:\/\/www.nature.com\/articles\/srep41127#supplementary-information","journal-title":"Sci Rep"},{"issue":"1","key":"2018_CR92","doi-asserted-by":"publisher","first-page":"210","DOI":"10.1016\/j.bbrc.2014.10.064","volume":"454","author":"M Xiang","year":"2014","unstructured":"Xiang M, Zeng Y, Yang R, Xu H, Chen Z, Zhong J, Xie H, Xu Y et al (2014) U6 is not a suitable endogenous control for the quantification of circulating microRNAs. Biochem Biophys Res Commun 454(1):210\u2013214. https:\/\/doi.org\/10.1016\/j.bbrc.2014.10.064","journal-title":"Biochem Biophys Res Commun"},{"key":"2018_CR93","doi-asserted-by":"publisher","first-page":"36","DOI":"10.3389\/fneur.2013.00036","volume":"4","author":"R Pressler","year":"2013","unstructured":"Pressler R, Auvin S (2013) Comparison of brain maturation among species: an example in translational research suggesting the possible use of bumetanide in newborn. Front Neurol 4:36\u201336. https:\/\/doi.org\/10.3389\/fneur.2013.00036","journal-title":"Front Neurol"},{"issue":"2","key":"2018_CR94","doi-asserted-by":"publisher","first-page":"115","DOI":"10.1016\/S0378-3782(96)01773-2","volume":"47","author":"T Roohey","year":"1997","unstructured":"Roohey T, Raju TN, Moustogiannis AN (1997) Animal models for the study of perinatal hypoxic-ischemic encephalopathy: a critical analysis. Early Hum Dev 47(2):115\u2013146","journal-title":"Early Hum Dev"},{"issue":"3","key":"2018_CR95","doi-asserted-by":"publisher","first-page":"e459","DOI":"10.1542\/peds.2008-2190","volume":"124","author":"DM Murray","year":"2009","unstructured":"Murray DM, Boylan GB, Ryan CA, Connolly S (2009) Early EEG findings in hypoxic-ischemic encephalopathy predict outcomes at 2 years. Pediatrics 124(3):e459\u2013e467. https:\/\/doi.org\/10.1542\/peds.2008-2190","journal-title":"Pediatrics"},{"issue":"1","key":"2018_CR96","doi-asserted-by":"publisher","first-page":"43","DOI":"10.1016\/S0387-7604(87)80009-8","volume":"9","author":"HB Sarnat","year":"1987","unstructured":"Sarnat HB (1987) Hypoxic alterations in neonatal neurons: an acridine orange fluorochromic study of nucleic acids. Brain and Development 9(1):43\u201347","journal-title":"Brain and Development"},{"key":"2018_CR97","doi-asserted-by":"publisher","unstructured":"Looney A-M, Ahearne C, Boylan GB, Murray DM (2015) Glial fibrillary acidic protein is not an early marker of injury in perinatal asphyxia and hypoxic\u2013ischemic encephalopathy. Front Neurol 6(264). https:\/\/doi.org\/10.3389\/fneur.2015.00264","DOI":"10.3389\/fneur.2015.00264"},{"key":"2018_CR98","unstructured":"Andrews S (2010) FastQC: a quality control tool for high throughput sequence data."},{"key":"2018_CR99","unstructured":"Team RC (2013) R: a language and environment for statistical computing."},{"issue":"2","key":"2018_CR100","doi-asserted-by":"publisher","first-page":"115","DOI":"10.1038\/nmeth.3252","volume":"12","author":"W Huber","year":"2015","unstructured":"Huber W, Carey VJ, Gentleman R, Anders S, Carlson M, Carvalho BS, Bravo HC, Davis S et al (2015) Orchestrating high-throughput genomic analysis with bioconductor. Nat Methods 12(2):115\u2013121","journal-title":"Nat Methods"},{"issue":"1","key":"2018_CR101","doi-asserted-by":"publisher","first-page":"139","DOI":"10.1093\/bioinformatics\/btp616","volume":"26","author":"MD Robinson","year":"2010","unstructured":"Robinson MD, McCarthy DJ, Smyth GK (2010) edgeR: a bioconductor package for differential expression analysis of digital gene expression data. Bioinformatics 26(1):139\u2013140","journal-title":"Bioinformatics"},{"key":"2018_CR102","doi-asserted-by":"crossref","unstructured":"Law CW, Alhamdoosh M, Su S, Smyth GK, Ritchie ME (2016) RNA-seq analysis is easy as 1-2-3 with limma, Glimma and edgeR. F1000Research 5","DOI":"10.12688\/f1000research.9005.2"},{"issue":"3","key":"2018_CR103","doi-asserted-by":"publisher","first-page":"R25","DOI":"10.1186\/gb-2010-11-3-r25","volume":"11","author":"MD Robinson","year":"2010","unstructured":"Robinson MD, Oshlack A (2010) A scaling normalization method for differential expression analysis of RNA-seq data. Genome Biol 11(3):R25","journal-title":"Genome Biol"},{"issue":"11","key":"2018_CR104","doi-asserted-by":"publisher","first-page":"4255","DOI":"10.1073\/pnas.1214046110","volume":"110","author":"Z Williams","year":"2013","unstructured":"Williams Z, Ben-Dov IZ, Elias R, Mihailovic A, Brown M, Rosenwaks Z, Tuschl T (2013) Comprehensive profiling of circulating microRNA via small RNA sequencing of cDNA libraries reveals biomarker potential and limitations. Proc Natl Acad Sci 110(11):4255\u20134260","journal-title":"Proc Natl Acad Sci"},{"issue":"12","key":"2018_CR105","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0207952","volume":"13","author":"GP Brennan","year":"2018","unstructured":"Brennan GP, Vitsios DM, Casey S, Looney A-M, Hallberg B, Henshall DC, Boylan GB, Murray DM et al (2018) RNA-sequencing analysis of umbilical cord plasma microRNAs from healthy newborns. PLoS One 13(12):e0207952. https:\/\/doi.org\/10.1371\/journal.pone.0207952","journal-title":"PLoS One"},{"key":"2018_CR106","doi-asserted-by":"publisher","first-page":"e1132","DOI":"10.1038\/cddis.2014.92","volume":"5","author":"Q Chen","year":"2014","unstructured":"Chen Q, Xu J, Li L, Li H, Mao S, Zhang F, Zen K, Zhang CY et al (2014) MicroRNA-23a\/b and microRNA-27a\/b suppress Apaf-1 protein and alleviate hypoxia-induced neuronal apoptosis. Cell Death Dis 5:e1132. https:\/\/doi.org\/10.1038\/cddis.2014.92 https:\/\/www.nature.com\/articles\/cddis201492#supplementary-information","journal-title":"Cell Death Dis"},{"key":"2018_CR107","doi-asserted-by":"publisher","first-page":"667","DOI":"10.1038\/sj.cdd.4402310","volume":"15","author":"R Kulshreshtha","year":"2008","unstructured":"Kulshreshtha R, Davuluri RV, Calin GA, Ivan M (2008) A microRNA component of the hypoxic response. Cell Death Differ 15:667\u2013671. https:\/\/doi.org\/10.1038\/sj.cdd.4402310. https:\/\/www.nature.com\/articles\/4402310#supplementary-information","journal-title":"Cell Death Differ"},{"issue":"5a","key":"2018_CR108","doi-asserted-by":"publisher","first-page":"1426","DOI":"10.1111\/j.1582-4934.2008.00398.x","volume":"12","author":"M Ivan","year":"2008","unstructured":"Ivan M, Harris Adrian L, Martelli F, Kulshreshtha R (2008) Hypoxia response and microRNAs: no longer two separate worlds. J Cell Mol Med 12(5a):1426\u20131431. https:\/\/doi.org\/10.1111\/j.1582-4934.2008.00398.x","journal-title":"J Cell Mol Med"},{"issue":"13","key":"2018_CR109","doi-asserted-by":"publisher","first-page":"1627","DOI":"10.1093\/cvr\/cvx157","volume":"113","author":"G Ceolotto","year":"2017","unstructured":"Ceolotto G, Giannella A, Albiero M, Kuppusamy M, Radu C, Simioni P, Garlaschelli K, Baragetti A et al (2017) miR-30c-5p regulates macrophage-mediated inflammation and pro-atherosclerosis pathways. Cardiovasc Res 113(13):1627\u20131638. https:\/\/doi.org\/10.1093\/cvr\/cvx157","journal-title":"Cardiovasc Res"},{"issue":"3","key":"2018_CR110","doi-asserted-by":"publisher","first-page":"713","DOI":"10.1007\/s11033-014-3819-9","volume":"42","author":"Z Oksuz","year":"2015","unstructured":"Oksuz Z, Serin MS, Kaplan E, Dogen A, Tezcan S, Aslan G, Emekdas G, Sezgin O et al (2015) Serum microRNAs; miR-30c-5p, miR-223-3p, miR-302c-3p and miR-17-5p could be used as novel non-invasive biomarkers for HCV-positive cirrhosis and hepatocellular carcinoma. Mol Biol Rep 42(3):713\u2013720","journal-title":"Mol Biol Rep"},{"issue":"12","key":"2018_CR111","doi-asserted-by":"publisher","first-page":"1609","DOI":"10.1111\/cas.12291","volume":"104","author":"J Huang","year":"2013","unstructured":"Huang J, Yao X, Zhang J, Dong B, Chen Q, Xue W, Liu D, Huang Y (2013) Hypoxia-induced downregulation of miR-30c promotes epithelial-mesenchymal transition in human renal cell carcinoma. Cancer Sci 104(12):1609\u20131617","journal-title":"Cancer Sci"},{"key":"2018_CR112","doi-asserted-by":"publisher","first-page":"7105","DOI":"10.1158\/1078-0432.CCR-11-0071","volume":"17","author":"Y Zhu","year":"2011","unstructured":"Zhu Y, Yu F, Jiao Y, Feng J, Tang W, Yao H, Gong C, Chen J et al (2011) Reduced miR-128 in breast tumor\u2013initiating cells induces chemotherapeutic resistance via Bmi-1 and ABCC5. Clin Cancer Res 17:7105\u20137115","journal-title":"Clin Cancer Res"},{"issue":"15","key":"2018_CR113","doi-asserted-by":"publisher","first-page":"1884","DOI":"10.1038\/onc.2011.380","volume":"31","author":"T Papagiannakopoulos","year":"2012","unstructured":"Papagiannakopoulos T, Friedmann-Morvinski D, Neveu P, Dugas J, Gill R, Huillard E, Liu C, Zong H et al (2012) Pro-neural miR-128 is a glioma tumor suppressor that targets mitogenic kinases. Oncogene 31(15):1884\u20131895","journal-title":"Oncogene"},{"issue":"13","key":"2018_CR114","doi-asserted-by":"publisher","first-page":"1651","DOI":"10.1038\/onc.2012.190","volume":"32","author":"T Palumbo","year":"2013","unstructured":"Palumbo T, Faucz FR, Azevedo M, Xekouki P, Iliopoulos D, Stratakis CA (2013) Functional screen analysis reveals miR-26b and miR-128 as central regulators of pituitary somatomammotrophic tumor growth through activation of the PTEN\u2013AKT pathway. Oncogene 32(13):1651\u20131659","journal-title":"Oncogene"},{"key":"2018_CR115","doi-asserted-by":"publisher","first-page":"4065","DOI":"10.1038\/onc.2009.274","volume":"28","author":"B Song","year":"2009","unstructured":"Song B, Wang Y, Xi Y, Kudo K, Bruheim S, Botchkina GI, Gavin E, Wan Y et al (2009) Mechanism of chemoresistance mediated by miR-140 in human osteosarcoma and colon cancer cells. Oncogene 28:4065\u20134074. https:\/\/doi.org\/10.1038\/onc.2009.274. https:\/\/www.nature.com\/articles\/onc2009274#supplementary-information","journal-title":"Oncogene"},{"issue":"1","key":"2018_CR116","doi-asserted-by":"publisher","first-page":"148","DOI":"10.1186\/1471-2474-10-148","volume":"10","author":"G Tardif","year":"2009","unstructured":"Tardif G, Hum D, Pelletier J-P, Duval N, Martel-Pelletier J (2009) Regulation of the IGFBP-5 and MMP-13 genes by the microRNAs miR-140 and miR-27a in human osteoarthritic chondrocytes. BMC Musculoskelet Disord 10(1):148. https:\/\/doi.org\/10.1186\/1471-2474-10-148","journal-title":"BMC Musculoskelet Disord"},{"key":"2018_CR117","doi-asserted-by":"publisher","first-page":"2589","DOI":"10.1038\/onc.2013.226","volume":"33","author":"Q Li","year":"2013","unstructured":"Li Q, Yao Y, Eades G, Liu Z, Zhang Y, Zhou Q (2013) Downregulation of miR-140 promotes cancer stem cell formation in basal-like early stage breast cancer. Oncogene 33:2589\u20132600. https:\/\/doi.org\/10.1038\/onc.2013.226. https:\/\/www.nature.com\/articles\/onc2013226#supplementary-information","journal-title":"Oncogene"},{"issue":"7","key":"2018_CR118","doi-asserted-by":"publisher","first-page":"1170","DOI":"10.1007\/s11605-010-1202-2","volume":"14","author":"Y Chen","year":"2010","unstructured":"Chen Y, Song Y, Wang Z, Yue Z, Xu H, Xing C, Liu Z (2010) Altered expression of MiR-148a and MiR-152 in gastrointestinal cancers and its clinical significance. J Gastrointest Surg 14(7):1170\u20131179. https:\/\/doi.org\/10.1007\/s11605-010-1202-2","journal-title":"J Gastrointest Surg"},{"issue":"6","key":"2018_CR119","doi-asserted-by":"publisher","first-page":"526","DOI":"10.1016\/j.biopsych.2010.10.010","volume":"69","author":"M Mui\u00f1os-Gimeno","year":"2011","unstructured":"Mui\u00f1os-Gimeno M, Espinosa-Parrilla Y, Guidi M, Kagerbauer B, Sipil\u00e4 T, Maron E, Pettai K, Kananen L et al (2011) Human microRNAs miR-22, miR-138-2, miR-148a, and miR-488 are associated with panic disorder and regulate several anxiety candidate genes and related pathways. Biol Psychiatry 69(6):526\u2013533. https:\/\/doi.org\/10.1016\/j.biopsych.2010.10.010","journal-title":"Biol Psychiatry"},{"issue":"1","key":"2018_CR120","doi-asserted-by":"publisher","first-page":"150","DOI":"10.1172\/JCI64946","volume":"123","author":"MA Taylor","year":"2013","unstructured":"Taylor MA, Sossey-Alaoui K, Thompson CL, Danielpour D, Schiemann WP (2013) TGF-\u03b2 upregulates miR-181a expression to promote breast cancer metastasis. J Clin Invest 123(1):150\u2013163. https:\/\/doi.org\/10.1172\/JCI64946","journal-title":"J Clin Invest"},{"issue":"11","key":"2018_CR121","doi-asserted-by":"publisher","first-page":"3072","DOI":"10.1182\/blood-2011-01-333484","volume":"118","author":"R Visone","year":"2011","unstructured":"Visone R, Veronese A, Rassenti LZ, Balatti V, Pearl DK, Acunzo M, Volinia S, Taccioli C et al (2011) miR-181b is a biomarker of disease progression in chronic lymphocytic leukemia. Blood 118(11):3072\u20133079","journal-title":"Blood"},{"key":"2018_CR122","doi-asserted-by":"crossref","unstructured":"Cai J, Guan H, Fang L, Yang Y, Zhu X, Yuan J, Wu J, Li M (2013) MicroRNA-374a activates Wnt\/\u03b2-catenin signaling to promote breast cancer metastasis. J Clin Invest 123(2)","DOI":"10.1172\/JCI65871"},{"issue":"3","key":"2018_CR123","doi-asserted-by":"publisher","first-page":"407","DOI":"10.1016\/j.febslet.2014.12.027","volume":"589","author":"X Xu","year":"2014","unstructured":"Xu X, Wang W, Su N, Zhu X, Yao J, Gao W, Hu Z, Sun Y (2014) miR-374a promotes cell proliferation, migration and invasion by targeting SRCIN1 in gastric cancer. FEBS Lett 589(3):407\u2013413. https:\/\/doi.org\/10.1016\/j.febslet.2014.12.027","journal-title":"FEBS Lett"},{"issue":"10","key":"2018_CR124","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0077251","volume":"8","author":"N Pescador","year":"2013","unstructured":"Pescador N, P\u00e9rez-Barba M, Ibarra JM, Corbat\u00f3n A, Mart\u00ednez-Larrad MT, Serrano-R\u00edos M (2013) Serum circulating microRNA profiling for identification of potential type 2 diabetes and obesity biomarkers. PLoS One 8(10):e77251. https:\/\/doi.org\/10.1371\/journal.pone.0077251","journal-title":"PLoS One"},{"key":"2018_CR125","unstructured":"Hegarty SV, Sullivan AM, O\u2019Keefe GW (2016) Protocol for evaluation of neurotrophic strategies in Parkinson\u2019s disease-related dopaminergic and sympathetic neurons in vitro."},{"key":"2018_CR126","doi-asserted-by":"publisher","first-page":"53193","DOI":"10.3791\/53193","volume":"108","author":"MM Shipley","year":"2016","unstructured":"Shipley MM, Mangold CA, Szpara ML (2016) Differentiation of the SH-SY5Y human neuroblastoma cell line. J Vis Exp : JoVE 108:53193\u201353193. https:\/\/doi.org\/10.3791\/53193","journal-title":"J Vis Exp : JoVE"},{"issue":"10","key":"2018_CR127","doi-asserted-by":"publisher","first-page":"1953","DOI":"10.1007\/s00424-013-1429-3","volume":"466","author":"T Baars","year":"2014","unstructured":"Baars T, Skyschally A, Klein-Hitpass L, Cario E, Erbel R, Heusch G, Kleinbongard P (2014) microRNA expression and its potential role in cardioprotection by ischemic postconditioning in pigs. Pflugers Arch 466(10):1953\u20131961. https:\/\/doi.org\/10.1007\/s00424-013-1429-3","journal-title":"Pflugers Arch"},{"issue":"3","key":"2018_CR128","doi-asserted-by":"publisher","first-page":"217","DOI":"10.1111\/iji.12198","volume":"42","author":"H Wang","year":"2015","unstructured":"Wang H, Wang J, Sun S, Wang Y, Guo J, Ning C, Yang K, Liu JF (2015) Identification of reference microRNAs for quantitative expression analysis in porcine peripheral blood mononuclear cells treated with polyinosinic-polycytidylic acid. Int J Immunogenet 42(3):217\u2013225. https:\/\/doi.org\/10.1111\/iji.12198","journal-title":"Int J Immunogenet"},{"issue":"4","key":"2018_CR129","doi-asserted-by":"publisher","first-page":"402","DOI":"10.1006\/meth.2001.1262","volume":"25","author":"KJ Livak","year":"2001","unstructured":"Livak KJ, Schmittgen TD (2001) Analysis of relative gene expression data using real-time quantitative PCR and the 2(\u2212Delta Delta C(T)) method. Methods (San Diego, Calif) 25(4):402\u2013408. https:\/\/doi.org\/10.1006\/meth.2001.1262","journal-title":"Methods (San Diego, Calif)"},{"issue":"1","key":"2018_CR130","doi-asserted-by":"publisher","first-page":"35","DOI":"10.1006\/jmre.1997.1244","volume":"129","author":"L Vanhamme","year":"1997","unstructured":"Vanhamme L, van den Boogaart A, Van Huffel S (1997) Improved method for accurate and efficient quantification of MRS data with use of prior knowledge. J Magn Reson 129(1):35\u201343. https:\/\/doi.org\/10.1006\/jmre.1997.1244","journal-title":"J Magn Reson"},{"issue":"D1","key":"2018_CR131","doi-asserted-by":"publisher","first-page":"D146","DOI":"10.1093\/nar\/gku1104","volume":"43","author":"N Wong","year":"2014","unstructured":"Wong N, Wang X (2014) miRDB: an online resource for microRNA target prediction and functional annotations. Nucleic Acids Res 43(D1):D146\u2013D152","journal-title":"Nucleic Acids Res"},{"issue":"1","key":"2018_CR132","doi-asserted-by":"publisher","first-page":"12","DOI":"10.1016\/j.mce.2008.12.013","volume":"302","author":"T Yuen","year":"2009","unstructured":"Yuen T, Ruf F, Chu T, Sealfon SC (2009) Microtranscriptome regulation by gonadotropin-releasing hormone. Mol Cell Endocrinol 302(1):12\u201317. https:\/\/doi.org\/10.1016\/j.mce.2008.12.013","journal-title":"Mol Cell Endocrinol"},{"issue":"4","key":"2018_CR133","doi-asserted-by":"publisher","first-page":"834","DOI":"10.1002\/jcb.22592","volume":"110","author":"RS Dave","year":"2010","unstructured":"Dave RS, Khalili K (2010) Morphine treatment of human monocyte-derived macrophages induces differential miRNA and protein expression: impact on inflammation and oxidative stress in the central nervous system. J Cell Biochem 110(4):834\u2013845. https:\/\/doi.org\/10.1002\/jcb.22592","journal-title":"J Cell Biochem"},{"issue":"19","key":"2018_CR134","doi-asserted-by":"publisher","first-page":"2811","DOI":"10.1093\/bioinformatics\/btu393","volume":"30","author":"B Brors","year":"2014","unstructured":"Brors B, Gu L, Schlesner M, Eils R, Gu Z (2014) Circlize implements and enhances circular visualization in R. Bioinformatics 30(19):2811\u20132812. https:\/\/doi.org\/10.1093\/bioinformatics\/btu393","journal-title":"Bioinformatics"},{"issue":"W1","key":"2018_CR135","doi-asserted-by":"publisher","first-page":"W90","DOI":"10.1093\/nar\/gkw377","volume":"44","author":"MV Kuleshov","year":"2016","unstructured":"Kuleshov MV, Jones MR, Rouillard AD, Fernandez NF, Duan Q, Wang Z, Koplev S, Jenkins SL et al (2016) Enrichr: a comprehensive gene set enrichment analysis web server 2016 update. Nucleic Acids Res 44(W1):W90\u2013W97","journal-title":"Nucleic Acids Res"},{"issue":"2","key":"2018_CR136","doi-asserted-by":"publisher","first-page":"R29","DOI":"10.1186\/gb-2014-15-2-r29","volume":"15","author":"CW Law","year":"2014","unstructured":"Law CW, Chen Y, Shi W, Smyth GK (2014) Voom: Precision weights unlock linear model analysis tools for RNA-seq read counts. Genome Biol 15(2):R29","journal-title":"Genome Biol"},{"issue":"7","key":"2018_CR137","doi-asserted-by":"publisher","first-page":"e47","DOI":"10.1093\/nar\/gkv007","volume":"43","author":"ME Ritchie","year":"2015","unstructured":"Ritchie ME, Phipson B, Wu D, Hu Y, Law CW, Shi W, Smyth GK (2015) Limma powers differential expression analyses for RNA-sequencing and microarray studies. Nucleic Acids Res 43(7):e47","journal-title":"Nucleic Acids Res"},{"key":"2018_CR138","doi-asserted-by":"crossref","unstructured":"Benjamini Y, Hochberg Y (1995) Controlling the false discovery rate: a practical and powerful approach to multiple testing. J Royal Stat Soc (Methodological):289\u2013300","DOI":"10.1111\/j.2517-6161.1995.tb02031.x"}],"container-title":["Molecular Neurobiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12035-020-02018-w.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s12035-020-02018-w\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12035-020-02018-w.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,9]],"date-time":"2025-04-09T02:12:43Z","timestamp":1744164763000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s12035-020-02018-w"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,7,27]]},"references-count":138,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2020,10]]}},"alternative-id":["2018"],"URL":"https:\/\/doi.org\/10.1007\/s12035-020-02018-w","relation":{},"ISSN":["0893-7648","1559-1182"],"issn-type":[{"value":"0893-7648","type":"print"},{"value":"1559-1182","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,7,27]]},"assertion":[{"value":"15 April 2020","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"8 July 2020","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"27 July 2020","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with Ethical Standards"}},{"value":"The authors declare that they have no conflict of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of Interest"}},{"value":"The BiHIVE 1 & 2 studies were approved respectively by the Clinical Ethics Committee of the Cork Teaching Hospitals and the Stockholm Ethical Review Board, and informed written consent was given by parents.All animal work was performed under the supervision of Dr. Tracey Bjorkman, University of Queensland, Australia. Approval was obtained from the University of Queensland Animal Experimentation Ethics Committee and was performed in accordance with National Health and Medicine Research Council Australia guidelines.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics Approval"}}]}}