{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,18]],"date-time":"2026-01-18T10:24:21Z","timestamp":1768731861519,"version":"3.49.0"},"reference-count":183,"publisher":"Springer Science and Business Media LLC","issue":"4","license":[{"start":{"date-parts":[[2022,1,18]],"date-time":"2022-01-18T00:00:00Z","timestamp":1642464000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2022,1,18]],"date-time":"2022-01-18T00:00:00Z","timestamp":1642464000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81700729"],"award-info":[{"award-number":["81700729"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Mol Neurobiol"],"published-print":{"date-parts":[[2022,4]]},"DOI":"10.1007\/s12035-021-02700-7","type":"journal-article","created":{"date-parts":[[2022,1,18]],"date-time":"2022-01-18T09:17:50Z","timestamp":1642497470000},"page":"2009-2026","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Recent Investigations on Neurotransmitters\u2019 Role in Acute White Matter Injury of Perinatal Glia and Pharmacotherapies\u2014Glia Dynamics in Stem Cell Therapy"],"prefix":"10.1007","volume":"59","author":[{"given":"Narasimha M.","family":"Beeraka","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P. R. Hemanth","family":"Vikram","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M. V.","family":"Greeshma","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chinnappa A.","family":"Uthaiah","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tahani","family":"Huria","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Junqi","family":"Liu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pramod","family":"Kumar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vladimir N.","family":"Nikolenko","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kirill V.","family":"Bulygin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mikhail Y.","family":"Sinelnikov","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Olga","family":"Sukocheva","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3401-4315","authenticated-orcid":false,"given":"Ruitai","family":"Fan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2022,1,18]]},"reference":[{"issue":"4","key":"2700_CR1","doi-asserted-by":"publisher","first-page":"997","DOI":"10.1542\/peds.2004-0221","volume":"115","author":"D Wilson-Costello","year":"2005","unstructured":"Wilson-Costello D, Friedman H, Minich N, Fanaroff AA, Hack M (2005) Improved survival rates with increased neurodevelopmental disability for extremely low birth weight infants in the 1990s. Pediatrics 115(4):997\u20131003","journal-title":"Pediatrics"},{"issue":"6","key":"2700_CR2","doi-asserted-by":"publisher","first-page":"e119","DOI":"10.1111\/j.1469-8749.2010.03612.x","volume":"52","author":"G Beaino","year":"2010","unstructured":"Beaino G, Khoshnood B, Kaminski M, Pierrat V, Marret S, Matis J, Ledesert B, Thiriez G, Fresson J, ROZ\u00c9 JC, (2010) Predictors of cerebral palsy in very preterm infants: the EPIPAGE prospective population-based cohort study. Dev Med Child Neurol 52(6):e119\u2013e125","journal-title":"Dev Med Child Neurol"},{"issue":"3","key":"2700_CR3","doi-asserted-by":"publisher","first-page":"318","DOI":"10.1001\/jama.294.3.318","volume":"294","author":"M Hack","year":"2005","unstructured":"Hack M, Taylor HG, Drotar D, Schluchter M, Cartar L, Andreias L, Wilson-Costello D, Klein N (2005) Chronic conditions, functional limitations, and special health care needs of school-aged children born with extremely low-birth-weight in the 1990s. JAMA 294(3):318\u2013325","journal-title":"JAMA"},{"issue":"09","key":"2700_CR4","doi-asserted-by":"publisher","first-page":"535","DOI":"10.1055\/s-0028-1083841","volume":"25","author":"J Liu","year":"2008","unstructured":"Liu J, Li J, Qin G-L, Chen Y-H, Wang Q (2008) Periventricular leukomalacia in premature infants in mainland China. Am J Perinatol 25(09):535\u2013540","journal-title":"Am J Perinatol"},{"issue":"4","key":"2700_CR5","doi-asserted-by":"publisher","first-page":"329","DOI":"10.1159\/000260136","volume":"97","author":"Mercier CE, Dunn MS, Ferrelli KR, Howard DB, Soll RF, Group VONEIF-US","year":"2010","unstructured":"Mercier CE, Dunn MS, Ferrelli KR, Howard DB, Soll RF, Group VONEIF-US (2010) Neurodevelopmental outcome of extremely low birth weight infants from the Vermont Oxford network: 1998\u20132003. Neonatology 97(4):329\u2013338","journal-title":"Neonatology"},{"issue":"5","key":"2700_CR6","doi-asserted-by":"publisher","first-page":"609","DOI":"10.1016\/j.jpeds.2005.06.033","volume":"147","author":"SP Miller","year":"2005","unstructured":"Miller SP, Ferriero DM, Leonard C, Piecuch R, Glidden DV, Partridge JC, Perez M, Mukherjee P, Vigneron DB, Barkovich AJ (2005) Early brain injury in premature newborns detected with magnetic resonance imaging is associated with adverse early neurodevelopmental outcome. J Pediatr 147(5):609\u2013616","journal-title":"J Pediatr"},{"issue":"7","key":"2700_CR7","doi-asserted-by":"publisher","first-page":"647","DOI":"10.1016\/j.ijdevneu.2008.08.001","volume":"26","author":"S Soria-Pastor","year":"2008","unstructured":"Soria-Pastor S, Gimenez M, Narberhaus A, Falcon C, Botet F, Bargallo N, Mercader JM, Junque C (2008) Patterns of cerebral white matter damage and cognitive impairment in adolescents born very preterm. Int J Dev Neurosci 26(7):647\u2013654","journal-title":"Int J Dev Neurosci"},{"issue":"1","key":"2700_CR8","doi-asserted-by":"publisher","first-page":"110","DOI":"10.1016\/S1474-4422(08)70294-1","volume":"8","author":"JJ Volpe","year":"2009","unstructured":"Volpe JJ (2009) Brain injury in premature infants: a complex amalgam of destructive and developmental disturbances. The Lancet Neurology 8(1):110\u2013124","journal-title":"The Lancet Neurology"},{"issue":"4","key":"2700_CR9","doi-asserted-by":"publisher","first-page":"225","DOI":"10.1038\/sj.jp.7211664","volume":"27","author":"JC Constantinou","year":"2007","unstructured":"Constantinou JC, Adamson-Macedo EN, Mirmiran M, Fleisher BE (2007) Movement, imaging and neurobehavioral assessment as predictors of cerebral palsy in preterm infants. J Perinatol 27(4):225\u2013229","journal-title":"J Perinatol"},{"issue":"2","key":"2700_CR10","doi-asserted-by":"publisher","first-page":"512","DOI":"10.1542\/peds.2008-0590","volume":"123","author":"AJ Spittle","year":"2009","unstructured":"Spittle AJ, Boyd RN, Inder TE, Doyle LW (2009) Predicting motor development in very preterm infants at 12 months\u2019 corrected age: the role of qualitative magnetic resonance imaging and general movements assessments. Pediatrics 123(2):512\u2013517","journal-title":"Pediatrics"},{"issue":"5","key":"2700_CR11","doi-asserted-by":"publisher","first-page":"e1184","DOI":"10.1542\/peds.2007-1924","volume":"121","author":"AJ Spittle","year":"2008","unstructured":"Spittle AJ, Brown NC, Doyle LW, Boyd RN, Hunt RW, Bear M, Inder TE (2008) Quality of general movements is related to white matter pathology in very preterm infants. Pediatrics 121(5):e1184\u2013e1189","journal-title":"Pediatrics"},{"issue":"2","key":"2700_CR12","doi-asserted-by":"publisher","first-page":"717","DOI":"10.1542\/peds.2008-2816","volume":"124","author":"CSH Aarnoudse-Moens","year":"2009","unstructured":"Aarnoudse-Moens CSH, Weisglas-Kuperus N, van Goudoever JB, Oosterlaan J (2009) Meta-analysis of neurobehavioral outcomes in very preterm and\/or very low birth weight children. Pediatrics 124(2):717\u2013728","journal-title":"Pediatrics"},{"key":"2700_CR13","doi-asserted-by":"crossref","unstructured":"Anderson PJ, Doyle LW Cognitive and educational deficits in children born extremely preterm. In: Seminars in perinatology, 2008. vol 1. Elsevier, pp 51\u201358","DOI":"10.1053\/j.semperi.2007.12.009"},{"issue":"6","key":"2700_CR14","doi-asserted-by":"publisher","first-page":"1485","DOI":"10.1542\/peds.2008-1216","volume":"123","author":"M Delobel-Ayoub","year":"2009","unstructured":"Delobel-Ayoub M, Arnaud C, White-Koning M, Casper C, Pierrat V, Garel M, Burguet A, Roze J-C, Matis J, Picaud J-C (2009) Behavioral problems and cognitive performance at 5 years of age after very preterm birth: the EPIPAGE Study. Pediatrics 123(6):1485\u20131492","journal-title":"Pediatrics"},{"key":"2700_CR15","doi-asserted-by":"crossref","unstructured":"Kesler SR, Reiss AL, Vohr B, Watson C, Schneider KC, Katz KH, Maller-Kesselman J, Silbereis J, Constable RT, Makuch RW (2008) Brain volume reductions within multiple cognitive systems in male preterm children at age twelve. The Journal of pediatrics 152 (4):513\u2013520. e511","DOI":"10.1016\/j.jpeds.2007.08.009"},{"issue":"5","key":"2700_CR16","doi-asserted-by":"publisher","first-page":"2464","DOI":"10.1523\/JNEUROSCI.14-05-02464.1994","volume":"14","author":"H Sontheimer","year":"1994","unstructured":"Sontheimer H, Fernandez-Marques E, Ullrich N, Pappas C, Waxman S (1994) Astrocyte Na+ channels are required for maintenance of Na+\/K (+)-ATPase activity. J Neurosci 14(5):2464\u20132475","journal-title":"J Neurosci"},{"issue":"5","key":"2700_CR17","doi-asserted-by":"publisher","first-page":"532","DOI":"10.1002\/cne.21974","volume":"513","author":"FA Azevedo","year":"2009","unstructured":"Azevedo FA, Carvalho LR, Grinberg LT, Farfel JM, Ferretti RE, Leite RE, Filho WJ, Lent R, Herculano-Houzel S (2009) Equal numbers of neuronal and nonneuronal cells make the human brain an isometrically scaled-up primate brain. Journal of Comparative Neurology 513(5):532\u2013541","journal-title":"Journal of Comparative Neurology"},{"issue":"9","key":"2700_CR18","doi-asserted-by":"publisher","first-page":"1377","DOI":"10.1002\/glia.22683","volume":"62","author":"S Herculano-Houzel","year":"2014","unstructured":"Herculano-Houzel S (2014) The glia\/neuron ratio: how it varies uniformly across brain structures and species and what that means for brain physiology and evolution. Glia 62(9):1377\u20131391","journal-title":"Glia"},{"key":"2700_CR19","doi-asserted-by":"publisher","first-page":"24","DOI":"10.3389\/fncel.2017.00024","volume":"11","author":"S J\u00e4kel","year":"2017","unstructured":"J\u00e4kel S, Dimou L (2017) Glial cells and their function in the adult brain: a journey through the history of their ablation. Front Cell Neurosci 11:24","journal-title":"Front Cell Neurosci"},{"key":"2700_CR20","doi-asserted-by":"crossref","unstructured":"Marcus A, Gowen BG, Thompson TW, Iannello A, Ardolino M, Deng W, Wang L, Shifrin N, Raulet DH (2014) Recognition of tumors by the innate immune system and natural killer cells. In: Advances in immunology, vol 122. Elsevier, pp 91\u2013128","DOI":"10.1016\/B978-0-12-800267-4.00003-1"},{"issue":"4","key":"2700_CR21","doi-asserted-by":"publisher","first-page":"1466","DOI":"10.1046\/j.1471-4159.1999.721466.x","volume":"72","author":"M Sawada","year":"1999","unstructured":"Sawada M, Suzumura A, Hosoya H, Marunouchi T, Nagatsu T (1999) Interleukin-10 inhibits both production of cytokines and expression of cytokine receptors in microglia. J Neurochem 72(4):1466\u20131471","journal-title":"J Neurochem"},{"key":"2700_CR22","doi-asserted-by":"publisher","first-page":"3609","DOI":"10.1007\/s10072-020-04468-5","volume":"41","author":"AR Saitgareeva","year":"2020","unstructured":"Saitgareeva AR, Bulygin KV, Gareev IF, Beylerli OA, Akhmadeeva LR (2020) The role of microglia in the development of neurodegeneration. Neurol Sci 41:3609\u20133615","journal-title":"Neurol Sci"},{"key":"2700_CR23","unstructured":"Chen W (2010) Regional Heterogeneity and Diversity of Astrocytes in Response to HIV-1 Proteins and Morphine."},{"issue":"9","key":"2700_CR24","doi-asserted-by":"publisher","first-page":"2192","DOI":"10.1523\/JNEUROSCI.3965-04.2005","volume":"25","author":"G Perea","year":"2005","unstructured":"Perea G, Araque A (2005) Properties of synaptically evoked astrocyte calcium signal reveal synaptic information processing by astrocytes. J Neurosci 25(9):2192\u20132203","journal-title":"J Neurosci"},{"issue":"3","key":"2700_CR25","doi-asserted-by":"publisher","first-page":"290","DOI":"10.1002\/glia.20060","volume":"47","author":"SC Lin","year":"2004","unstructured":"Lin SC, Bergles DE (2004) Synaptic signaling between neurons and glia. Glia 47(3):290\u2013298","journal-title":"Glia"},{"issue":"5\u20136","key":"2700_CR26","doi-asserted-by":"publisher","first-page":"514","DOI":"10.1097\/FBP.0b013e32833d41b2","volume":"21","author":"KJ Reissner","year":"2010","unstructured":"Reissner KJ, Kalivas PW (2010) Using glutamate homeostasis as a target for treating addictive disorders. Behav Pharmacol 21(5\u20136):514","journal-title":"Behav Pharmacol"},{"key":"2700_CR27","doi-asserted-by":"crossref","unstructured":"Baydyuk M, Morrison VE, Gross PS, Huang JK (2020) Extrinsic factors driving oligodendrocyte lineage cell progression in CNS development and injury. Neurochemical Research:1\u201313","DOI":"10.1007\/s11064-020-02967-7"},{"issue":"1","key":"2700_CR28","doi-asserted-by":"publisher","first-page":"34","DOI":"10.1523\/JNEUROSCI.20-01-00034.2000","volume":"20","author":"R Fern","year":"2000","unstructured":"Fern R, M\u00f6ller T (2000) Rapid ischemic cell death in immature oligodendrocytes: a fatal glutamate release feedback loop. J Neurosci 20(1):34\u201342","journal-title":"J Neurosci"},{"issue":"2","key":"2700_CR29","doi-asserted-by":"publisher","first-page":"231","DOI":"10.1016\/S0014-4886(03)00032-3","volume":"181","author":"A Craig","year":"2003","unstructured":"Craig A, Luo NL, Beardsley DJ, Wingate-Pearse N, Walker DW, Hohimer AR, Back SA (2003) Quantitative analysis of perinatal rodent oligodendrocyte lineage progression and its correlation with human. Exp Neurol 181(2):231\u2013240","journal-title":"Exp Neurol"},{"key":"2700_CR30","doi-asserted-by":"crossref","unstructured":"Larsen BR, MacAulay N (2014) Kir4. 1-mediated spatial buffering of K+: experimental challenges in determination of its temporal and quantitative contribution to K+ clearance in the brain. Channels 8 (6):544\u2013550","DOI":"10.4161\/19336950.2014.970448"},{"key":"2700_CR31","doi-asserted-by":"publisher","first-page":"141","DOI":"10.3389\/fphys.2016.00141","volume":"7","author":"BR Larsen","year":"2016","unstructured":"Larsen BR, Stoica A, MacAulay N (2016) Managing brain extracellular K+ during neuronal activity: the physiological role of the Na+\/K+-ATPase subunit isoforms. Front Physiol 7:141","journal-title":"Front Physiol"},{"issue":"3","key":"2700_CR32","doi-asserted-by":"publisher","first-page":"162","DOI":"10.1177\/107385849600200311","volume":"2","author":"I Steffensen","year":"1996","unstructured":"Steffensen I, Stys PK (1996) REVIEW\u25a0: The Na-Ca exchanger in neurons and glial cells. Neuroscientist 2(3):162\u2013171","journal-title":"Neuroscientist"},{"issue":"1","key":"2700_CR33","doi-asserted-by":"publisher","first-page":"35","DOI":"10.1002\/glia.20183","volume":"51","author":"CL Floyd","year":"2005","unstructured":"Floyd CL, Gorin FA, Lyeth BG (2005) Mechanical strain injury increases intracellular sodium and reverses Na+\/Ca2+ exchange in cortical astrocytes. Glia 51(1):35\u201346","journal-title":"Glia"},{"issue":"6","key":"2700_CR34","doi-asserted-by":"publisher","first-page":"468","DOI":"10.1007\/s11515-011-1187-6","volume":"6","author":"T Luo","year":"2011","unstructured":"Luo T, Wu W-H, Chen B-S (2011) NMDA receptor signaling: death or survival? Frontiers in biology 6(6):468\u2013476","journal-title":"Frontiers in biology"},{"issue":"6","key":"2700_CR35","doi-asserted-by":"publisher","first-page":"693","DOI":"10.1111\/j.1469-7580.2007.00733.x","volume":"210","author":"C Matute","year":"2007","unstructured":"Matute C, Alberdi E, Domercq M, S\u00e1nchez-G\u00f3mez MV, P\u00e9rez-Samart\u00edn A, Rodr\u00edguez-Antig\u00fcedad A, P\u00e9rez-Cerd\u00e1 F (2007) Excitotoxic damage to white matter. J Anat 210(6):693\u2013702","journal-title":"J Anat"},{"issue":"2","key":"2700_CR36","doi-asserted-by":"publisher","first-page":"284","DOI":"10.1016\/j.nbd.2006.09.011","volume":"25","author":"SM Underhill","year":"2007","unstructured":"Underhill SM, Goldberg MP (2007) Hypoxic injury of isolated axons is independent of ionotropic glutamate receptors. Neurobiol Dis 25(2):284\u2013290","journal-title":"Neurobiol Dis"},{"issue":"6","key":"2700_CR37","doi-asserted-by":"publisher","first-page":"861","DOI":"10.1089\/neu.2008.0645","volume":"26","author":"YC Chen","year":"2009","unstructured":"Chen YC, Smith DH, Meaney DF (2009) In-vitro approaches for studying blast-induced traumatic brain injury. J Neurotrauma 26(6):861\u2013876","journal-title":"J Neurotrauma"},{"issue":"5","key":"2700_CR38","doi-asserted-by":"publisher","first-page":"522","DOI":"10.1089\/ars.2011.4391","volume":"18","author":"J Lewerenz","year":"2013","unstructured":"Lewerenz J, Hewett SJ, Huang Y, Lambros M, Gout PW, Kalivas PW, Massie A, Smolders I, Methner A, Pergande M (2013) The cystine\/glutamate antiporter system xc\u2212 in health and disease: from molecular mechanisms to novel therapeutic opportunities. Antioxid Redox Signal 18(5):522\u2013555","journal-title":"Antioxid Redox Signal"},{"issue":"3","key":"2700_CR39","doi-asserted-by":"publisher","first-page":"106","DOI":"10.1046\/j.1440-1789.2002.00438.x","volume":"22","author":"P Rezaie","year":"2002","unstructured":"Rezaie P, Dean A (2002) Periventricular leukomalacia, inflammation and white matter lesions within the developing nervous system. Neuropathology 22(3):106\u2013132","journal-title":"Neuropathology"},{"issue":"2","key":"2700_CR40","doi-asserted-by":"publisher","first-page":"724","DOI":"10.1161\/01.STR.0000254729.27386.05","volume":"38","author":"SA Back","year":"2007","unstructured":"Back SA, Riddle A, McClure MM (2007) Maturation-dependent vulnerability of perinatal white matter in premature birth. Stroke 38(2):724\u2013730","journal-title":"Stroke"},{"issue":"4","key":"2700_CR41","doi-asserted-by":"publisher","first-page":"1302","DOI":"10.1523\/JNEUROSCI.21-04-01302.2001","volume":"21","author":"SA Back","year":"2001","unstructured":"Back SA, Luo NL, Borenstein NS, Levine JM, Volpe JJ, Kinney HC (2001) Late oligodendrocyte progenitors coincide with the developmental window of vulnerability for human perinatal white matter injury. J Neurosci 21(4):1302\u20131312","journal-title":"J Neurosci"},{"issue":"7071","key":"2700_CR42","doi-asserted-by":"publisher","first-page":"1167","DOI":"10.1038\/nature04301","volume":"438","author":"MG Salter","year":"2005","unstructured":"Salter MG, Fern R (2005) NMDA receptors are expressed in developing oligodendrocyte processes and mediate injury. Nature 438(7071):1167\u20131171","journal-title":"Nature"},{"issue":"2","key":"2700_CR43","doi-asserted-by":"publisher","first-page":"233","DOI":"10.1002\/glia.20608","volume":"56","author":"Y Bakiri","year":"2008","unstructured":"Bakiri Y, Hamilton NB, K\u00e1rad\u00f3ttir R, Attwell D (2008) Testing NMDA receptor block as a therapeutic strategy for reducing ischaemic damage to CNS white matter. Glia 56(2):233\u2013240","journal-title":"Glia"},{"issue":"3","key":"2700_CR44","doi-asserted-by":"publisher","first-page":"544","DOI":"10.1002\/hipo.20920","volume":"22","author":"S Rosi","year":"2012","unstructured":"Rosi S, Belarbi K, Ferguson RA, Fishman K, Obenaus A, Raber J, Fike JR (2012) Trauma-induced alterations in cognition and Arc expression are reduced by previous exposure to 56Fe irradiation. Hippocampus 22(3):544\u2013554","journal-title":"Hippocampus"},{"issue":"26","key":"2700_CR45","doi-asserted-by":"publisher","first-page":"6670","DOI":"10.1523\/JNEUROSCI.1702-08.2008","volume":"28","author":"SM Manning","year":"2008","unstructured":"Manning SM, Talos DM, Zhou C, Selip DB, Park H-K, Park C-J, Volpe JJ, Jensen FE (2008) NMDA receptor blockade with memantine attenuates white matter injury in a rat model of periventricular leukomalacia. J Neurosci 28(26):6670\u20136678","journal-title":"J Neurosci"},{"issue":"18","key":"2700_CR46","doi-asserted-by":"publisher","first-page":"7232","DOI":"10.1523\/JNEUROSCI.18-18-07232.1998","volume":"18","author":"R Fern","year":"1998","unstructured":"Fern R (1998) Intracellular calcium and cell death during ischemia in neonatal rat white matter astrocytes in situ. J Neurosci 18(18):7232\u20137243","journal-title":"J Neurosci"},{"issue":"2","key":"2700_CR47","first-page":"324","volume":"3","author":"A Najafi","year":"2017","unstructured":"Najafi A, Etezadi F, Moharari RS, Pourfakhr P, Khajavi MR (2017) The role of neurotransmitters in anesthesia. Archives of Anesthesiology and Critical Care 3(2):324\u2013333","journal-title":"Archives of Anesthesiology and Critical Care"},{"key":"2700_CR48","doi-asserted-by":"publisher","first-page":"86","DOI":"10.1016\/j.neulet.2018.11.031","volume":"694","author":"R Fern","year":"2019","unstructured":"Fern R, Matute C (2019) Glutamate receptors and white matter stroke. Neurosci Lett 694:86\u201392","journal-title":"Neurosci Lett"},{"issue":"4","key":"2700_CR49","doi-asserted-by":"publisher","first-page":"1204","DOI":"10.1161\/STROKEAHA.112.658328","volume":"44","author":"C Matute","year":"2013","unstructured":"Matute C, Domercq M, P\u00e9rez-Samart\u00edn A, Ransom BR (2013) Protecting white matter from stroke injury. Stroke 44(4):1204\u20131211","journal-title":"Stroke"},{"key":"2700_CR50","doi-asserted-by":"publisher","first-page":"51","DOI":"10.3389\/fncel.2020.00051","volume":"14","author":"D Belov Kirdajova","year":"2020","unstructured":"Belov Kirdajova D, Kriska J, Tureckova J, Anderova M (2020) Ischemia-triggered glutamate excitotoxicity from the perspective of glial cells. Front Cell Neurosci 14:51","journal-title":"Front Cell Neurosci"},{"key":"2700_CR51","unstructured":"Wolke SA (2018) Mechanisms of reward in depression: an intervention study investigating the acute effects of lurasidone on cerebral blood flow and the neural correlates of reward and penalty processing. King\u2019s College London,"},{"issue":"5","key":"2700_CR52","doi-asserted-by":"publisher","first-page":"1092","DOI":"10.1093\/cercor\/bhp181","volume":"20","author":"A Desfeux","year":"2010","unstructured":"Desfeux A, El Ghazi F, J\u00e9gou S, Legros H, Marret S, Laudenbach V, Gonzalez BJ (2010) Dual effect of glutamate on GABAergic interneuron survival during cerebral cortex development in mice neonates. Cereb Cortex 20(5):1092\u20131108","journal-title":"Cereb Cortex"},{"issue":"24","key":"2700_CR53","doi-asserted-by":"publisher","first-page":"7898","DOI":"10.1523\/JNEUROSCI.6129-08.2009","volume":"29","author":"TM DeSilva","year":"2009","unstructured":"DeSilva TM, Kabakov AY, Goldhoff PE, Volpe JJ, Rosenberg PA (2009) Regulation of glutamate transport in developing rat oligodendrocytes. J Neurosci 29(24):7898\u20137908","journal-title":"J Neurosci"},{"issue":"3","key":"2700_CR54","doi-asserted-by":"publisher","first-page":"295","DOI":"10.1016\/0301-0082(92)90020-F","volume":"39","author":"CF Zorumski","year":"1992","unstructured":"Zorumski CF, Thio LL (1992) Properties of vertebrate glutamate receptors: calcium mobilization and desensitization. Prog Neurobiol 39(3):295\u2013336","journal-title":"Prog Neurobiol"},{"key":"2700_CR55","doi-asserted-by":"crossref","unstructured":"Raj GM, Raveendran R (2019) Introduction to Basics of Pharmacology and Toxicology: Volume 1: General and Molecular Pharmacology: Principles of Drug Action. Springer Nature,","DOI":"10.1007\/978-981-32-9779-1"},{"issue":"3","key":"2700_CR56","doi-asserted-by":"publisher","first-page":"405","DOI":"10.1124\/pr.109.002451","volume":"62","author":"SF Traynelis","year":"2010","unstructured":"Traynelis SF, Wollmuth LP, McBain CJ, Menniti FS, Vance KM, Ogden KK, Hansen KB, Yuan H, Myers SJ, Dingledine R (2010) Glutamate receptor ion channels: structure, regulation, and function. Pharmacol Rev 62(3):405\u2013496","journal-title":"Pharmacol Rev"},{"issue":"33","key":"2700_CR57","doi-asserted-by":"publisher","first-page":"24151","DOI":"10.1074\/jbc.M113.482000","volume":"288","author":"X Zhou","year":"2013","unstructured":"Zhou X, Ding Q, Chen Z, Yun H, Wang H (2013) Involvement of the GluN2A and GluN2B subunits in synaptic and extrasynaptic N-methyl-D-aspartate receptor function and neuronal excitotoxicity. J Biol Chem 288(33):24151\u201324159","journal-title":"J Biol Chem"},{"issue":"1","key":"2700_CR58","first-page":"7","volume":"51","author":"R Dingledine","year":"1999","unstructured":"Dingledine R, Borges K, Bowie D, Traynelis SF (1999) The glutamate receptor ion channels. Pharmacol Rev 51(1):7\u201362","journal-title":"Pharmacol Rev"},{"key":"2700_CR59","doi-asserted-by":"crossref","unstructured":"Manteniotis S, Lehmann R, Flegel C, Vogel F, Hofreuter A, Schreiner BS, Altm\u00fcller J, Becker C, Sch\u00f6bel N, Hatt H (2013) Comprehensive RNA-Seq expression analysis of sensory ganglia with a focus on ion channels and GPCRs in Trigeminal ganglia. PloS one 8 (11):e79523","DOI":"10.1371\/journal.pone.0079523"},{"key":"2700_CR60","doi-asserted-by":"crossref","unstructured":"Yao L, Zhou Q (2017) Enhancing NMDA receptor function: recent progress on allosteric modulators. Neural Plasticity 2017","DOI":"10.1155\/2017\/2875904"},{"issue":"5","key":"2700_CR61","doi-asserted-by":"publisher","first-page":"887","DOI":"10.1016\/j.neuron.2012.03.039","volume":"74","author":"T Miyashita","year":"2012","unstructured":"Miyashita T, Oda Y, Horiuchi J, Yin JC, Morimoto T, Saitoe M (2012) Mg2+ block of Drosophila NMDA receptors is required for long-term memory formation and CREB-dependent gene expression. Neuron 74(5):887\u2013898","journal-title":"Neuron"},{"key":"2700_CR62","doi-asserted-by":"crossref","unstructured":"Bolton C, Paul C (2006) Glutamate receptors in neuroinflammatory demyelinating disease. Mediators of inflammation 2006","DOI":"10.1155\/MI\/2006\/93684"},{"issue":"5","key":"2700_CR63","doi-asserted-by":"publisher","first-page":"623","DOI":"10.1085\/jgp.112.5.623","volume":"112","author":"LP Wollmuth","year":"1998","unstructured":"Wollmuth LP, Sakmann B (1998) Different mechanisms of Ca2+ transport in NMDA and Ca2+-permeable AMPA glutamate receptor channels. J Gen Physiol 112(5):623\u2013636","journal-title":"J Gen Physiol"},{"issue":"2","key":"2700_CR64","doi-asserted-by":"publisher","first-page":"337","DOI":"10.1113\/jphysiol.2003.058842","volume":"556","author":"BM Kampa","year":"2004","unstructured":"Kampa BM, Clements J, Jonas P, Stuart GJ (2004) Kinetics of Mg2+ unblock of NMDA receptors: implications for spike-timing dependent synaptic plasticity. J Physiol 556(2):337\u2013345","journal-title":"J Physiol"},{"key":"2700_CR65","doi-asserted-by":"publisher","first-page":"29","DOI":"10.1016\/j.neuropharm.2016.08.023","volume":"112","author":"KR Tovar","year":"2017","unstructured":"Tovar KR, Westbrook GL (2017) Modulating synaptic NMDA receptors. Neuropharmacology 112:29\u201333","journal-title":"Neuropharmacology"},{"issue":"5","key":"2700_CR66","doi-asserted-by":"publisher","first-page":"1331","DOI":"10.1523\/JNEUROSCI.5242-05.2006","volume":"26","author":"J Neyton","year":"2006","unstructured":"Neyton J, Paoletti P (2006) Relating NMDA receptor function to receptor subunit composition: limitations of the pharmacological approach. J Neurosci 26(5):1331\u20131333","journal-title":"J Neurosci"},{"key":"2700_CR67","unstructured":"Li X (2009) The role of NR2A-and NR2B-containing NMDA receptors in innate anxiety. University of Ottawa (Canada),"},{"issue":"2","key":"2700_CR68","doi-asserted-by":"publisher","first-page":"212","DOI":"10.1002\/glia.20275","volume":"53","author":"C Matute","year":"2006","unstructured":"Matute C, Domercq M, S\u00e1nchez-G\u00f3mez MV (2006) Glutamate-mediated glial injury: mechanisms and clinical importance. Glia 53(2):212\u2013224","journal-title":"Glia"},{"issue":"1","key":"2700_CR69","doi-asserted-by":"publisher","first-page":"53","DOI":"10.1111\/j.1469-7580.2010.01339.x","volume":"219","author":"C Matute","year":"2011","unstructured":"Matute C (2011) Glutamate and ATP signalling in white matter pathology. J Anat 219(1):53\u201364","journal-title":"J Anat"},{"issue":"9","key":"2700_CR70","first-page":"1153","volume":"5","author":"S Nadjafi","year":"2014","unstructured":"Nadjafi S, Ebrahimi S-A, Rahbar-Roshandel N (2014) Protective effects of berberine on oxygen-glucose deprivation\/reperfusion on oligodendrocyte cell line (OLN-93). Int J Prev Med 5(9):1153","journal-title":"Int J Prev Med"},{"issue":"34","key":"2700_CR71","doi-asserted-by":"publisher","first-page":"11501","DOI":"10.1523\/JNEUROSCI.1593-10.2010","volume":"30","author":"JC Pi\u00f1a-Crespo","year":"2010","unstructured":"Pi\u00f1a-Crespo JC, Talantova M, Micu I, Chen H-SV, Tu S, Nakanishi N, Tong G, Zhang D, Heinemann SF, Zamponi GW (2010) Excitatory glycine responses of CNS myelin mediated by NR1\/NR3 \u201cNMDA\u201d receptor subunits. J Neurosci 30(34):11501\u201311505","journal-title":"J Neurosci"},{"issue":"18","key":"2700_CR72","doi-asserted-by":"publisher","first-page":"3403","DOI":"10.1113\/jphysiol.2010.195503","volume":"588","author":"V Burzomato","year":"2010","unstructured":"Burzomato V, Frugier G, P\u00e9rez-Ota\u00f1o I, Kittler JT, Attwell D (2010) The receptor subunits generating NMDA receptor mediated currents in oligodendrocytes. J Physiol 588(18):3403\u20133414","journal-title":"J Physiol"},{"issue":"2","key":"2700_CR73","doi-asserted-by":"publisher","first-page":"482","DOI":"10.1093\/cercor\/bht246","volume":"25","author":"LL Jantzie","year":"2015","unstructured":"Jantzie LL, Talos DM, Jackson MC, Park H-K, Graham DA, Lechpammer M, Folkerth RD, Volpe JJ, Jensen FE (2015) Developmental expression of N-methyl-D-aspartate (NMDA) receptor subunits in human white and gray matter: potential mechanism of increased vulnerability in the immature brain. Cereb Cortex 25(2):482\u2013495","journal-title":"Cereb Cortex"},{"issue":"1","key":"2700_CR74","doi-asserted-by":"publisher","first-page":"49","DOI":"10.1113\/jphysiol.2011.221689","volume":"590","author":"D Bowie","year":"2012","unstructured":"Bowie D (2012) Redefining the classification of AMPA-selective ionotropic glutamate receptors. J Physiol 590(1):49\u201361","journal-title":"J Physiol"},{"issue":"8","key":"2700_CR75","doi-asserted-by":"publisher","first-page":"1859","DOI":"10.1038\/sj.bjp.0703993","volume":"132","author":"WM Dai","year":"2001","unstructured":"Dai WM, Egebjerg J, Lambert JD (2001) Characteristics of AMPA receptor-mediated responses of cultured cortical and spinal cord neurones and their correlation to the expression of glutamate receptor subunits, GluR1-4. Br J Pharmacol 132(8):1859\u20131875","journal-title":"Br J Pharmacol"},{"issue":"24","key":"2700_CR76","doi-asserted-by":"publisher","first-page":"9393","DOI":"10.1523\/JNEUROSCI.17-24-09393.1997","volume":"17","author":"MS Washburn","year":"1997","unstructured":"Washburn MS, Numberger M, Zhang S, Dingledine R (1997) Differential dependence on GluR2 expression of three characteristic features of AMPA receptors. J Neurosci 17(24):9393\u20139406","journal-title":"J Neurosci"},{"issue":"2","key":"2700_CR77","doi-asserted-by":"publisher","first-page":"319","DOI":"10.1016\/j.neuron.2011.05.038","volume":"71","author":"J Kumar","year":"2011","unstructured":"Kumar J, Schuck P, Mayer ML (2011) Structure and assembly mechanism for heteromeric kainate receptors. Neuron 71(2):319\u2013331","journal-title":"Neuron"},{"issue":"4","key":"2700_CR78","doi-asserted-by":"publisher","first-page":"603","DOI":"10.1083\/jcb.144.4.603","volume":"144","author":"CR Eckmann","year":"1999","unstructured":"Eckmann CR, Jantsch MF (1999) The RNA-editing enzyme ADAR1 is localized to the nascent ribonucleoprotein matrix on Xenopus lampbrush chromosomes but specifically associates with an atypical loop. J Cell Biol 144(4):603\u2013615","journal-title":"J Cell Biol"},{"issue":"18","key":"2700_CR79","doi-asserted-by":"publisher","first-page":"4412","DOI":"10.1523\/JNEUROSCI.0477-04.2004","volume":"24","author":"PL Follett","year":"2004","unstructured":"Follett PL, Deng W, Dai W, Talos DM, Massillon LJ, Rosenberg PA, Volpe JJ, Jensen FE (2004) Glutamate receptor-mediated oligodendrocyte toxicity in periventricular leukomalacia: a protective role for topiramate. J Neurosci 24(18):4412\u20134420","journal-title":"J Neurosci"},{"key":"2700_CR80","doi-asserted-by":"publisher","first-page":"99","DOI":"10.3389\/fnins.2012.00099","volume":"6","author":"A Tariq","year":"2012","unstructured":"Tariq A, Jantsch MF (2012) Transcript diversification in the nervous system: A to I RNA-editing in CNS function and disease development. Front Neurosci 6:99","journal-title":"Front Neurosci"},{"key":"2700_CR81","doi-asserted-by":"publisher","first-page":"105","DOI":"10.1186\/gm508","volume":"5","author":"W Slotkin","year":"2013","unstructured":"Slotkin W, Nishikura K (2013) Adenosine-to-inosine RNA editing and human disease. Genome Med 5:105","journal-title":"Genome Med"},{"issue":"2","key":"2700_CR82","doi-asserted-by":"publisher","first-page":"83","DOI":"10.1038\/nrm.2015.4","volume":"17","author":"K Nishikura","year":"2016","unstructured":"Nishikura K (2016) A-to-I editing of coding and non-coding RNAs by ADARs. Nat Rev Mol Cell Biol 17(2):83\u201396","journal-title":"Nat Rev Mol Cell Biol"},{"issue":"8","key":"2700_CR83","doi-asserted-by":"publisher","first-page":"882","DOI":"10.1134\/S0006297911080037","volume":"76","author":"A Barbon","year":"2011","unstructured":"Barbon A, Barlati S (2011) Glutamate receptor RNA editing in health and disease. Biochem Mosc 76(8):882\u2013889","journal-title":"Biochem Mosc"},{"key":"2700_CR84","doi-asserted-by":"publisher","first-page":"34","DOI":"10.3389\/fnmol.2012.00034","volume":"5","author":"AL Wright","year":"2012","unstructured":"Wright AL, Vissel B (2012) The essential role of AMPA receptor GluR2 subunit RNA editing in the normal and diseased brain. Front Mol Neurosci 5:34","journal-title":"Front Mol Neurosci"},{"issue":"11","key":"2700_CR85","doi-asserted-by":"publisher","first-page":"1518","DOI":"10.1038\/nn.3539","volume":"16","author":"JB Li","year":"2013","unstructured":"Li JB, Church GM (2013) Deciphering the functions and regulation of brain-enriched A-to-I RNA editing. Nat Neurosci 16(11):1518\u20131522","journal-title":"Nat Neurosci"},{"issue":"1","key":"2700_CR86","doi-asserted-by":"publisher","first-page":"1","DOI":"10.4161\/rna.3.1.2495","volume":"3","author":"S Maas","year":"2006","unstructured":"Maas S, Kawahara Y, Tamburro KM, Nishikura K (2006) A-to-I RNA editing and human disease. RNA Biol 3(1):1\u20139","journal-title":"RNA Biol"},{"issue":"2","key":"2700_CR87","doi-asserted-by":"publisher","first-page":"110","DOI":"10.1007\/s00109-004-0599-z","volume":"83","author":"S Kwak","year":"2005","unstructured":"Kwak S, Kawahara Y (2005) Deficient RNA editing of GluR2 and neuronal death in amyotropic lateral sclerosis. J Mol Med 83(2):110\u2013120","journal-title":"J Mol Med"},{"issue":"10","key":"2700_CR88","doi-asserted-by":"publisher","first-page":"4326","DOI":"10.1074\/jbc.M117.779868","volume":"292","author":"E Oakes","year":"2017","unstructured":"Oakes E, Anderson A, Cohen-Gadol A, Hundley HA (2017) Adenosine deaminase that acts on RNA 3 (ADAR3) binding to glutamate receptor subunit B pre-mRNA inhibits RNA editing in glioblastoma. J Biol Chem 292(10):4326\u20134335","journal-title":"J Biol Chem"},{"issue":"6","key":"2700_CR89","doi-asserted-by":"publisher","first-page":"2052","DOI":"10.1093\/bib\/bbz126","volume":"21","author":"A Mehmood","year":"2020","unstructured":"Mehmood A, Laiho A, Ven\u00e4l\u00e4inen MS, McGlinchey AJ, Wang N, Elo LL (2020) Systematic evaluation of differential splicing tools for RNA-seq studies. Brief Bioinform 21(6):2052\u20132065","journal-title":"Brief Bioinform"},{"issue":"3","key":"2700_CR90","doi-asserted-by":"publisher","first-page":"223","DOI":"10.1159\/000210185","volume":"31","author":"MM Jacobs","year":"2009","unstructured":"Jacobs MM, Fogg RL, Emeson RB, Stanwood GD (2009) ADAR1 and ADAR2 expression and editing activity during forebrain development. Dev Neurosci 31(3):223\u2013237","journal-title":"Dev Neurosci"},{"key":"2700_CR91","doi-asserted-by":"publisher","first-page":"69","DOI":"10.3389\/fncel.2015.00069","volume":"9","author":"S Pachernegg","year":"2015","unstructured":"Pachernegg S, M\u00fcnster Y, Muth-K\u00f6hne E, Fuhrmann G, Hollmann M (2015) GluA2 is rapidly edited at the Q\/R site during neural differentiation in vitro. Front Cell Neurosci 9:69","journal-title":"Front Cell Neurosci"},{"issue":"5191","key":"2700_CR92","doi-asserted-by":"publisher","first-page":"1709","DOI":"10.1126\/science.7992055","volume":"266","author":"H Lomeli","year":"1994","unstructured":"Lomeli H, Mosbacher J, Melcher T, Hoger T, Kuner T, Monyer H, Higuchi M, Bach A, Seeburg PH (1994) Control of kinetic properties of AMPA receptor channels by nuclear RNA editing. Science 266(5191):1709\u20131713","journal-title":"Science"},{"issue":"6","key":"2700_CR93","doi-asserted-by":"publisher","first-page":"978","DOI":"10.1101\/gr.089409.108","volume":"19","author":"H Wahlstedt","year":"2009","unstructured":"Wahlstedt H, Daniel C, Enster\u00f6 M, \u00d6hman M (2009) Large-scale mRNA sequencing determines global regulation of RNA editing during brain development. Genome Res 19(6):978\u2013986","journal-title":"Genome Res"},{"issue":"5242","key":"2700_CR94","doi-asserted-by":"publisher","first-page":"1677","DOI":"10.1126\/science.270.5242.1677","volume":"270","author":"R Brusa","year":"1995","unstructured":"Brusa R, Zimmermann F, Koh D-S, Feldmeyer D, Gass P, Seeburg PH, Sprengel R (1995) Early-onset epilepsy and postnatal lethality associated with an editing-deficient GluR-B allele in mice. Science 270(5242):1677\u20131680","journal-title":"Science"},{"issue":"6791","key":"2700_CR95","doi-asserted-by":"publisher","first-page":"78","DOI":"10.1038\/35017558","volume":"406","author":"M Higuchi","year":"2000","unstructured":"Higuchi M, Maas S, Single FN, Hartner J, Rozov A, Burnashev N, Feldmeyer D, Sprengel R, Seeburg PH (2000) Point mutation in an AMPA receptor gene rescues lethality in mice deficient in the RNA-editing enzyme ADAR2. Nature 406(6791):78\u201381","journal-title":"Nature"},{"issue":"9","key":"2700_CR96","doi-asserted-by":"publisher","first-page":"6795","DOI":"10.1007\/s12035-016-0201-z","volume":"54","author":"A Filippini","year":"2017","unstructured":"Filippini A, Bonini D, La Via L, Barbon A (2017) The good and the bad of glutamate receptor RNA editing. Mol Neurobiol 54(9):6795\u20136805","journal-title":"Mol Neurobiol"},{"issue":"1","key":"2700_CR97","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1186\/s13041-020-0545-1","volume":"13","author":"LM Konen","year":"2020","unstructured":"Konen LM, Wright AL, Royle GA, Morris GP, Lau BK, Seow PW, Zinn R, Milham LT, Vaughan CW, Vissel B (2020) A new mouse line with reduced GluA2 Q\/R site RNA editing exhibits loss of dendritic spines, hippocampal CA1-neuron loss, learning and memory impairments and NMDA receptor-independent seizure vulnerability. Mol Brain 13(1):1\u201319","journal-title":"Mol Brain"},{"key":"2700_CR98","doi-asserted-by":"crossref","unstructured":"Herbrechter R, Hube N, Buchholz R, Reiner A (2021) Splicing and editing of ionotropic glutamate receptors: a comprehensive analysis based on human RNA-Seq data. Cellular and Molecular Life Sciences:1\u201326","DOI":"10.1007\/s00018-021-03865-z"},{"issue":"1","key":"2700_CR99","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1186\/s12885-019-6068-4","volume":"19","author":"B Xiao","year":"2019","unstructured":"Xiao B, Chen D, Zhou Q, Hang J, Zhang W, Kuang Z, Sun Z, Li L (2019) Glutamate metabotropic receptor 4 (GRM4) inhibits cell proliferation, migration and invasion in breast cancer and is regulated by miR-328-3p and miR-370-3p. BMC Cancer 19(1):1\u201310","journal-title":"BMC Cancer"},{"issue":"39","key":"2700_CR100","doi-asserted-by":"publisher","first-page":"9983","DOI":"10.1523\/JNEUROSCI.2773-06.2006","volume":"26","author":"D Billups","year":"2006","unstructured":"Billups D, Billups B, Challiss RJ, Nahorski SR (2006) Modulation of Gq-protein-coupled inositol trisphosphate and Ca2+ signaling by the membrane potential. J Neurosci 26(39):9983\u20139995","journal-title":"J Neurosci"},{"key":"2700_CR101","doi-asserted-by":"publisher","first-page":"58","DOI":"10.3389\/fphar.2015.00058","volume":"6","author":"RO Godinho","year":"2015","unstructured":"Godinho RO, Duarte T, Pacini ESA (2015) New perspectives in signaling mediated by receptors coupled to stimulatory G protein: the emerging significance of cAMP efflux and extracellular cAMP-adenosine pathway. Front Pharmacol 6:58","journal-title":"Front Pharmacol"},{"issue":"24","key":"2700_CR102","doi-asserted-by":"publisher","first-page":"20176","DOI":"10.1074\/jbc.M112.347468","volume":"287","author":"C Ramos","year":"2012","unstructured":"Ramos C, Chardonnet S, Marchand CH, Decottignies P, Ango F, Daniel H, Le Mar\u00e9chal P (2012) Native presynaptic metabotropic glutamate receptor 4 (mGluR4) interacts with exocytosis proteins in rat cerebellum. J Biol Chem 287(24):20176\u201320186","journal-title":"J Biol Chem"},{"issue":"3","key":"2700_CR103","doi-asserted-by":"publisher","first-page":"451","DOI":"10.1016\/j.ajhg.2017.08.005","volume":"101","author":"LM Watson","year":"2017","unstructured":"Watson LM, Bamber E, Schnekenberg RP, Williams J, Bettencourt C, Lickiss J, Jayawant S, Fawcett K, Clokie S, Wallis Y (2017) Dominant mutations in GRM1 cause spinocerebellar ataxia type 44. The American Journal of Human Genetics 101(3):451\u2013458","journal-title":"The American Journal of Human Genetics"},{"issue":"1","key":"2700_CR104","doi-asserted-by":"publisher","first-page":"89","DOI":"10.1124\/pharmrev.120.000011","volume":"73","author":"T Sch\u00f6neberg","year":"2021","unstructured":"Sch\u00f6neberg T, Liebscher I (2021) Mutations in G protein\u2013coupled receptors: mechanisms, pathophysiology and potential therapeutic approaches. Pharmacol Rev 73(1):89\u2013119","journal-title":"Pharmacol Rev"},{"issue":"17","key":"2700_CR105","doi-asserted-by":"publisher","first-page":"6000","DOI":"10.1523\/JNEUROSCI.5347-11.2012","volume":"32","author":"S Holmseth","year":"2012","unstructured":"Holmseth S, Dehnes Y, Huang YH, Follin-Arbelet VV, Grutle NJ, Mylonakou MN, Plachez C, Zhou Y, Furness DN, Bergles DE (2012) The density of EAAC1 (EAAT3) glutamate transporters expressed by neurons in the mammalian CNS. J Neurosci 32(17):6000\u20136013","journal-title":"J Neurosci"},{"issue":"7","key":"2700_CR106","doi-asserted-by":"publisher","first-page":"375","DOI":"10.1016\/j.tips.2006.05.003","volume":"27","author":"U Gether","year":"2006","unstructured":"Gether U, Andersen PH, Larsson OM, Schousboe A (2006) Neurotransmitter transporters: molecular function of important drug targets. Trends Pharmacol Sci 27(7):375\u2013383","journal-title":"Trends Pharmacol Sci"},{"issue":"5","key":"2700_CR107","doi-asserted-by":"publisher","first-page":"694","DOI":"10.1016\/j.str.2013.03.002","volume":"21","author":"PJ Focke","year":"2013","unstructured":"Focke PJ, Wang X, Larsson HP (2013) Neurotransmitter transporters: structure meets function. Structure 21(5):694\u2013705","journal-title":"Structure"},{"issue":"1","key":"2700_CR108","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1007\/s00232-004-0731-6","volume":"203","author":"C Grewer","year":"2005","unstructured":"Grewer C, Rauen T (2005) Electrogenic glutamate transporters in the CNS: molecular mechanism, pre-steady-state kinetics, and their impact on synaptic signaling. J Membr Biol 203(1):1\u201320","journal-title":"J Membr Biol"},{"issue":"3","key":"2700_CR109","doi-asserted-by":"publisher","first-page":"321","DOI":"10.1038\/nn1854","volume":"10","author":"JL Ziskin","year":"2007","unstructured":"Ziskin JL, Nishiyama A, Rubio M, Fukaya M, Bergles DE (2007) Vesicular release of glutamate from unmyelinated axons in white matter. Nat Neurosci 10(3):321\u2013330","journal-title":"Nat Neurosci"},{"issue":"4","key":"2700_CR110","doi-asserted-by":"publisher","first-page":"1320","DOI":"10.1523\/JNEUROSCI.23-04-01320.2003","volume":"23","author":"S Duan","year":"2003","unstructured":"Duan S, Anderson CM, Keung EC, Chen Y, Chen Y, Swanson RA (2003) P2X7 receptor-mediated release of excitatory amino acids from astrocytes. J Neurosci 23(4):1320\u20131328","journal-title":"J Neurosci"},{"issue":"8","key":"2700_CR111","doi-asserted-by":"publisher","first-page":"1429","DOI":"10.1002\/glia.22859","volume":"63","author":"L Dimou","year":"2015","unstructured":"Dimou L, Gallo V (2015) NG 2-glia and their functions in the central nervous system. Glia 63(8):1429\u20131451","journal-title":"Glia"},{"key":"2700_CR112","doi-asserted-by":"publisher","first-page":"418","DOI":"10.3389\/fnmol.2018.00418","volume":"11","author":"E Zieminska","year":"2018","unstructured":"Zieminska E, Toczylowska B, Diamandakis D, Hilgier W, Filipkowski RK, Polowy R, Orzel J, Gorka M, Lazarewicz JW (2018) Glutamate, glutamine and GABA levels in rat brain measured using MRS, HPLC and NMR methods in study of two models of autism. Front Mol Neurosci 11:418","journal-title":"Front Mol Neurosci"},{"issue":"15","key":"2700_CR113","doi-asserted-by":"publisher","first-page":"5706","DOI":"10.1523\/JNEUROSCI.18-15-05706.1998","volume":"18","author":"K Yamada","year":"1998","unstructured":"Yamada K, Watanabe M, Shibata T, Nagashima M, Tanaka K, Inoue Y (1998) Glutamate transporter GLT-1 is transiently localized on growing axons of the mouse spinal cord before establishing astrocytic expression. J Neurosci 18(15):5706\u20135713","journal-title":"J Neurosci"},{"issue":"5","key":"2700_CR114","doi-asserted-by":"publisher","first-page":"1159","DOI":"10.1038\/sj.npp.1301107","volume":"32","author":"A Pfefferbaum","year":"2007","unstructured":"Pfefferbaum A, Adalsteinsson E, Bell RL, Sullivan EV (2007) Development and resolution of brain lesions caused by pyrithiamine-and dietary-induced thiamine deficiency and alcohol exposure in the alcohol-preferring rat: a longitudinal magnetic resonance imaging and spectroscopy study. Neuropsychopharmacology 32(5):1159\u20131177","journal-title":"Neuropsychopharmacology"},{"issue":"11","key":"2700_CR115","doi-asserted-by":"publisher","first-page":"1790","DOI":"10.1002\/glia.22658","volume":"62","author":"SA Back","year":"2014","unstructured":"Back SA, Rosenberg PA (2014) Pathophysiology of glia in perinatal white matter injury. Glia 62(11):1790\u20131815","journal-title":"Glia"},{"issue":"6","key":"2700_CR116","doi-asserted-by":"publisher","first-page":"624","DOI":"10.4085\/1062-6050-44.6.624","volume":"44","author":"SL Volpe","year":"2009","unstructured":"Volpe SL, Poule KA, Bland EG (2009) Estimation of prepractice hydration status of National Collegiate Athletic Association Division I athletes. J Athl Train 44(6):624\u2013629","journal-title":"J Athl Train"},{"issue":"6\u20137","key":"2700_CR117","doi-asserted-by":"publisher","first-page":"333","DOI":"10.1016\/j.neuint.2007.03.012","volume":"51","author":"AL Sheldon","year":"2007","unstructured":"Sheldon AL, Robinson MB (2007) The role of glutamate transporters in neurodegenerative diseases and potential opportunities for intervention. Neurochem Int 51(6\u20137):333\u2013355","journal-title":"Neurochem Int"},{"issue":"2","key":"2700_CR118","doi-asserted-by":"publisher","first-page":"51","DOI":"10.5498\/wjp.v8.i2.51","volume":"8","author":"GM Parkin","year":"2018","unstructured":"Parkin GM, Udawela M, Gibbons A, Dean B (2018) Glutamate transporters, EAAT1 and EAAT2, are potentially important in the pathophysiology and treatment of schizophrenia and affective disorders. World journal of psychiatry 8(2):51","journal-title":"World journal of psychiatry"},{"issue":"4","key":"2700_CR119","doi-asserted-by":"publisher","first-page":"1426","DOI":"10.1016\/j.neuroscience.2006.08.070","volume":"145","author":"R K\u00e1rad\u00f3ttir","year":"2007","unstructured":"K\u00e1rad\u00f3ttir R, Attwell D (2007) Neurotransmitter receptors in the life and death of oligodendrocytes. Neuroscience 145(4):1426\u20131438","journal-title":"Neuroscience"},{"issue":"2","key":"2700_CR120","doi-asserted-by":"publisher","first-page":"152","DOI":"10.1369\/0022155411429704","volume":"60","author":"DM Svistunova","year":"2012","unstructured":"Svistunova DM, Musinova YR, Polyakov VY, Sheval EV (2012) A simple method for the immunocytochemical detection of proteins inside nuclear structures that are inaccessible to specific antibodies. J Histochem Cytochem 60(2):152\u2013158","journal-title":"J Histochem Cytochem"},{"issue":"12","key":"2700_CR121","doi-asserted-by":"publisher","first-page":"1353","DOI":"10.1002\/glia.20703","volume":"56","author":"AM Arranz","year":"2008","unstructured":"Arranz AM, Hussein A, Alix JJ, P\u00e9rez-Cerd\u00e1 F, Allcock N, Matute C, Fern R (2008) Functional glutamate transport in rodent optic nerve axons and glia. Glia 56(12):1353\u20131367","journal-title":"Glia"},{"issue":"5","key":"2700_CR122","doi-asserted-by":"publisher","first-page":"682","DOI":"10.1002\/ana.21767","volume":"66","author":"JJ Alix","year":"2009","unstructured":"Alix JJ, Fern R (2009) Glutamate receptor-mediated ischemic injury of premyelinated central axons. Annals of Neurology: Official Journal of the American Neurological Association and the Child Neurology Society 66(5):682\u2013693","journal-title":"Annals of Neurology: Official Journal of the American Neurological Association and the Child Neurology Society"},{"key":"2700_CR123","doi-asserted-by":"publisher","first-page":"203","DOI":"10.3389\/fnins.2020.00203","volume":"14","author":"MJ Rigby","year":"2020","unstructured":"Rigby MJ, Gomez TM, Puglielli L (2020) Glial cell-axonal growth cone interactions in neurodevelopment and regeneration. Front Neurosci 14:203","journal-title":"Front Neurosci"},{"issue":"9","key":"2700_CR124","doi-asserted-by":"publisher","first-page":"580","DOI":"10.1111\/j.1469-8749.2004.tb01021.x","volume":"46","author":"S \u00d8stensj\u00f8","year":"2004","unstructured":"\u00d8stensj\u00f8 S, Carlberg EB, V\u00f8llestad NK (2004) Motor impairments in young children with cerebral palsy: relationship to gross motor function and everyday activities. Dev Med Child Neurol 46(9):580\u2013589","journal-title":"Dev Med Child Neurol"},{"issue":"4","key":"2700_CR125","doi-asserted-by":"publisher","first-page":"543","DOI":"10.1038\/jcbfm.2014.227","volume":"35","author":"T Huria","year":"2015","unstructured":"Huria T, Beeraka NM, Al-Ghamdi B, Fern R (2015) Premyelinated central axons express neurotoxic NMDA receptors: relevance to early developing white-matter injury. J Cereb Blood Flow Metab 35(4):543\u2013553","journal-title":"J Cereb Blood Flow Metab"},{"key":"2700_CR126","doi-asserted-by":"crossref","unstructured":"Matute C, Ransom BR (2012) Roles of white matter in central nervous system pathophysiologies. ASN neuro 4 (2):AN20110060","DOI":"10.1042\/AN20110060"},{"key":"2700_CR127","doi-asserted-by":"publisher","first-page":"49","DOI":"10.3389\/fnana.2015.00049","volume":"9","author":"B Alghamdi","year":"2015","unstructured":"Alghamdi B, Fern R (2015) Phenotype overlap in glial cell populations: astroglia, oligodendroglia and NG-2 (+) cells. Front Neuroanat 9:49","journal-title":"Front Neuroanat"},{"key":"2700_CR128","doi-asserted-by":"crossref","unstructured":"Beeraka N, Huria T, Elgradawi M, Elzwei S (2017) Picrotoxin (GABAA receptor antagonist) shows a protective role in brain injury during neonatal development.","DOI":"10.37376\/1571-000-021-006"},{"issue":"6","key":"2700_CR129","doi-asserted-by":"publisher","first-page":"1924","DOI":"10.1046\/j.1460-9568.2000.00085.x","volume":"12","author":"S Belachew","year":"2000","unstructured":"Belachew S, Malgrange B, Rigo JM, Rogister B, Leprince P, Hans G, Nguyen L, Moonen G (2000) Glycine triggers an intracellular calcium influx in oligodendrocyte progenitor cells which is mediated by the activation of both the ionotropic glycine receptor and Na+-dependent transporters. Eur J Neurosci 12(6):1924\u20131930","journal-title":"Eur J Neurosci"},{"key":"2700_CR130","doi-asserted-by":"publisher","first-page":"193","DOI":"10.3389\/fncel.2013.00193","volume":"7","author":"D Li","year":"2013","unstructured":"Li D, Agulhon C, Schmidt E, Oheim M, Ropert N (2013) New tools for investigating astrocyte-to-neuron communication. Front Cell Neurosci 7:193","journal-title":"Front Cell Neurosci"},{"issue":"7","key":"2700_CR131","doi-asserted-by":"publisher","first-page":"2993","DOI":"10.1007\/s00429-017-1380-8","volume":"222","author":"M Papanikolaou","year":"2017","unstructured":"Papanikolaou M, Lewis A, Butt A (2017) Store-operated calcium entry is essential for glial calcium signalling in CNS white matter. Brain Struct Funct 222(7):2993\u20133005","journal-title":"Brain Struct Funct"},{"issue":"35","key":"2700_CR132","doi-asserted-by":"publisher","first-page":"12650","DOI":"10.1523\/JNEUROSCI.2455-11.2011","volume":"31","author":"LM De Biase","year":"2011","unstructured":"De Biase LM, Kang SH, Baxi EG, Fukaya M, Pucak ML, Mishina M, Calabresi PA, Bergles DE (2011) NMDA receptor signaling in oligodendrocyte progenitors is not required for oligodendrogenesis and myelination. J Neurosci 31(35):12650\u201312662","journal-title":"J Neurosci"},{"issue":"15","key":"2700_CR133","doi-asserted-by":"publisher","first-page":"4220","DOI":"10.1523\/JNEUROSCI.5542-06.2007","volume":"27","author":"WJ McCarran","year":"2007","unstructured":"McCarran WJ, Goldberg MP (2007) White matter axon vulnerability to AMPA\/kainate receptor-mediated ischemic injury is developmentally regulated. J Neurosci 27(15):4220\u20134229","journal-title":"J Neurosci"},{"issue":"3","key":"2700_CR134","doi-asserted-by":"publisher","first-page":"551","DOI":"10.1007\/s11064-018-02708-x","volume":"45","author":"E Su\u00e1rez-Pozos","year":"2020","unstructured":"Su\u00e1rez-Pozos E, Thomason EJ, Fuss B (2020) Glutamate Transporters: expression and function in oligodendrocytes. Neurochem Res 45(3):551\u2013560","journal-title":"Neurochem Res"},{"key":"2700_CR135","doi-asserted-by":"publisher","first-page":"451","DOI":"10.3389\/fnmol.2017.00451","volume":"10","author":"CR Rose","year":"2018","unstructured":"Rose CR, Felix L, Zeug A, Dietrich D, Reiner A, Henneberger C (2018) Astroglial glutamate signaling and uptake in the hippocampus. Front Mol Neurosci 10:451","journal-title":"Front Mol Neurosci"},{"issue":"4","key":"2700_CR136","doi-asserted-by":"publisher","first-page":"389","DOI":"10.1002\/glia.20174","volume":"50","author":"HK Kimelberg","year":"2005","unstructured":"Kimelberg HK (2005) Astrocytic swelling in cerebral ischemia as a possible cause of injury and target for therapy. Glia 50(4):389\u2013397","journal-title":"Glia"},{"issue":"5","key":"2700_CR137","doi-asserted-by":"publisher","first-page":"1583","DOI":"10.1523\/JNEUROSCI.10-05-01583.1990","volume":"10","author":"H Kimelberg","year":"1990","unstructured":"Kimelberg H, Goderie S, Higman S, Pang S, Waniewski R (1990) Swelling-induced release of glutamate, aspartate, and taurine from astrocyte cultures. J Neurosci 10(5):1583\u20131591","journal-title":"J Neurosci"},{"issue":"2","key":"2700_CR138","doi-asserted-by":"publisher","first-page":"390","DOI":"10.1046\/j.1471-4159.2002.00866.x","volume":"81","author":"T Itoh","year":"2002","unstructured":"Itoh T, Beesley J, Itoh A, Cohen AS, Kavanaugh B, Coulter DA, Grinspan JB, Pleasure D (2002) AMPA glutamate receptor-mediated calcium signaling is transiently enhanced during development of oligodendrocytes. J Neurochem 81(2):390\u2013402","journal-title":"J Neurochem"},{"issue":"11","key":"2700_CR139","doi-asserted-by":"publisher","first-page":"1780","DOI":"10.1002\/glia.22722","volume":"62","author":"RF Fern","year":"2014","unstructured":"Fern RF, Matute C, Stys PK (2014) White matter injury: Ischemic and nonischemic. Glia 62(11):1780\u20131789","journal-title":"Glia"},{"issue":"1","key":"2700_CR140","first-page":"29","volume":"35","author":"T Wierzba-Bobrowicz","year":"1997","unstructured":"Wierzba-Bobrowicz T, Lechowicz W, Kosno-Kruszewska E (1997) A morphometric evaluation of morphological types of microglia and astroglia in human fetal mesencephalon. Folia Neuropathol 35(1):29\u201335","journal-title":"Folia Neuropathol"},{"issue":"3","key":"2700_CR141","doi-asserted-by":"publisher","first-page":"308","DOI":"10.1007\/BF00686089","volume":"70","author":"U Roessmann","year":"1986","unstructured":"Roessmann U, Gambetti P (1986) Astrocytes in the developing human brain. Acta Neuropathol 70(3):308\u2013313","journal-title":"Acta Neuropathol"},{"key":"2700_CR142","doi-asserted-by":"publisher","first-page":"5","DOI":"10.3389\/neuro.05.005.2009","volume":"3","author":"I Jakovcevski","year":"2009","unstructured":"Jakovcevski I, Filipovic R, Mo Z, Rakic S, Zecevic N (2009) Oligodendrocyte development and the onset of myelination in the human fetal brain. Front Neuroanat 3:5","journal-title":"Front Neuroanat"},{"issue":"2","key":"2700_CR143","doi-asserted-by":"publisher","first-page":"156","DOI":"10.1002\/cne.20453","volume":"484","author":"RL Haynes","year":"2005","unstructured":"Haynes RL, Borenstein NS, Desilva TM, Folkerth RD, Liu LG, Volpe JJ, Kinney HC (2005) Axonal development in the cerebral white matter of the human fetus and infant. Journal of Comparative Neurology 484(2):156\u2013167","journal-title":"Journal of Comparative Neurology"},{"issue":"4","key":"2700_CR144","doi-asserted-by":"publisher","first-page":"584","DOI":"10.1203\/00006450-199810000-00019","volume":"44","author":"PS H\u00fcppi","year":"1998","unstructured":"H\u00fcppi PS, Maier SE, Peled S, Zientara GP, Barnes PD, Jolesz FA, Volpe JJ (1998) Microstructural development of human newborn cerebral white matter assessed in vivo by diffusion tensor magnetic resonance imaging. Pediatr Res 44(4):584\u2013590","journal-title":"Pediatr Res"},{"issue":"5","key":"2700_CR145","doi-asserted-by":"publisher","first-page":"1053","DOI":"10.1038\/jcbfm.2009.286","volume":"30","author":"JR Buser","year":"2010","unstructured":"Buser JR, Segovia KN, Dean JM, Nelson K, Beardsley D, Gong X, Luo NL, Ren J, Wan Y, Riddle A (2010) Timing of appearance of late oligodendrocyte progenitors coincides with enhanced susceptibility of preterm rabbit cerebral white matter to hypoxia-ischemia. J Cereb Blood Flow Metab 30(5):1053\u20131065","journal-title":"J Cereb Blood Flow Metab"},{"issue":"2","key":"2700_CR146","doi-asserted-by":"publisher","first-page":"109","DOI":"10.1002\/cne.20714","volume":"491","author":"N Zecevic","year":"2005","unstructured":"Zecevic N, Chen Y, Filipovic R (2005) Contributions of cortical subventricular zone to the development of the human cerebral cortex. Journal of Comparative Neurology 491(2):109\u2013122","journal-title":"Journal of Comparative Neurology"},{"issue":"2","key":"2700_CR147","doi-asserted-by":"publisher","first-page":"129","DOI":"10.1002\/mrdd.20107","volume":"12","author":"SA Back","year":"2006","unstructured":"Back SA (2006) Perinatal white matter injury: the changing spectrum of pathology and emerging insights into pathogenetic mechanisms. Ment Retard Dev Disabil Res Rev 12(2):129\u2013140","journal-title":"Ment Retard Dev Disabil Res Rev"},{"issue":"2","key":"2700_CR148","doi-asserted-by":"publisher","first-page":"F153","DOI":"10.1136\/adc.2006.108837","volume":"93","author":"O Khwaja","year":"2008","unstructured":"Khwaja O, Volpe J (2008) Pathogenesis of cerebral white matter injury of prematurity. Arch Dis Child Fetal Neonatal Ed 93(2):F153\u2013F161","journal-title":"Arch Dis Child Fetal Neonatal Ed"},{"issue":"4","key":"2700_CR149","doi-asserted-by":"publisher","first-page":"469","DOI":"10.1002\/ana.24132","volume":"75","author":"SA Back","year":"2014","unstructured":"Back SA, Miller SP (2014) Brain injury in premature neonates: a primary cerebral dysmaturation disorder? Ann Neurol 75(4):469\u2013486","journal-title":"Ann Neurol"},{"issue":"2","key":"2700_CR150","doi-asserted-by":"publisher","first-page":"153","DOI":"10.1111\/j.1750-3639.2007.00107.x","volume":"18","author":"SS Billiards","year":"2008","unstructured":"Billiards SS, Haynes RL, Folkerth RD, Borenstein NS, Trachtenberg FL, Rowitch DH, Ligon KL, Volpe JJ, Kinney HC (2008) Myelin abnormalities without oligodendrocyte loss in periventricular leukomalacia. Brain Pathol 18(2):153\u2013163","journal-title":"Brain Pathol"},{"issue":"1","key":"2700_CR151","doi-asserted-by":"publisher","first-page":"93","DOI":"10.1002\/ana.22627","volume":"71","author":"JR Buser","year":"2012","unstructured":"Buser JR, Maire J, Riddle A, Gong X, Nguyen T, Nelson K, Luo NL, Ren J, Struve J, Sherman LS (2012) Arrested preoligodendrocyte maturation contributes to myelination failure in premature infants. Ann Neurol 71(1):93\u2013109","journal-title":"Ann Neurol"},{"issue":"4","key":"2700_CR152","doi-asserted-by":"publisher","first-page":"480","DOI":"10.1002\/glia.20134","volume":"49","author":"I Jakovcevski","year":"2005","unstructured":"Jakovcevski I, Zecevic N (2005) Sequence of oligodendrocyte development in the human fetal telencephalon. Glia 49(4):480\u2013491","journal-title":"Glia"},{"issue":"8","key":"2700_CR153","doi-asserted-by":"publisher","first-page":"983","DOI":"10.1007\/BF00968708","volume":"19","author":"HC Kinney","year":"1994","unstructured":"Kinney HC, Karthigasan J, Borenshteyn NI, Flax JD, Kirschner DA (1994) Myelination in the developing human brain: biochemical correlates. Neurochem Res 19(8):983\u2013996","journal-title":"Neurochem Res"},{"issue":"4","key":"2700_CR154","doi-asserted-by":"publisher","first-page":"533","DOI":"10.1002\/ana.24115","volume":"75","author":"A Drobyshevsky","year":"2014","unstructured":"Drobyshevsky A, Jiang R, Lin L, Derrick M, Luo K, Back SA, Tan S (2014) Unmyelinated axon loss with postnatal hypertonia after fetal hypoxia. Ann Neurol 75(4):533\u2013541","journal-title":"Ann Neurol"},{"issue":"7","key":"2700_CR155","doi-asserted-by":"publisher","first-page":"480","DOI":"10.1016\/S0387-7604(97)00068-5","volume":"19","author":"SZ Meng","year":"1997","unstructured":"Meng SZ, Arai Y, Deguchi K, Takashima S (1997) Early detection of axonal and neuronal lesions in prenatal-onset periventricular leukomalacia. Brain Develop 19(7):480\u2013484","journal-title":"Brain Develop"},{"issue":"2","key":"2700_CR156","first-page":"87","volume":"20","author":"A Hirayama","year":"2001","unstructured":"Hirayama A, Okoshi Y, Hachiya Y, Ozawa Y, Ito M, Kida Y, Imai Y, Kohsaka S, Takashima S (2001) Early immunohistochemical detection of axonal damage and glial activation in extremely immature brains with periventricular leukomalacia. Clin Neuropathol 20(2):87\u201391","journal-title":"Clin Neuropathol"},{"issue":"6","key":"2700_CR157","doi-asserted-by":"publisher","first-page":"656","DOI":"10.1203\/PDR.0b013e31816c825c","volume":"63","author":"RL Haynes","year":"2008","unstructured":"Haynes RL, Billiards SS, Borenstein NS, Volpe JJ, Kinney HC (2008) Diffuse axonal injury in periventricular leukomalacia as determined by apoptotic marker fractin. Pediatr Res 63(6):656\u2013661","journal-title":"Pediatr Res"},{"issue":"4","key":"2700_CR158","doi-asserted-by":"publisher","first-page":"453","DOI":"10.1203\/00006450-200104000-00003","volume":"49","author":"O Dammann","year":"2001","unstructured":"Dammann O, Hagberg H, Leviton A (2001) Is periventricular leukomalacia an axonopathy as well as an oligopathy? Pediatr Res 49(4):453\u2013457","journal-title":"Pediatr Res"},{"issue":"1","key":"2700_CR159","doi-asserted-by":"publisher","first-page":"178","DOI":"10.1161\/STROKEAHA.111.632265","volume":"43","author":"A Riddle","year":"2012","unstructured":"Riddle A, Maire J, Gong X, Chen KX, Kroenke CD, Hohimer AR, Back SA (2012) Differential susceptibility to axonopathy in necrotic and non-necrotic perinatal white matter injury. Stroke 43(1):178\u2013184","journal-title":"Stroke"},{"issue":"17","key":"2700_CR160","doi-asserted-by":"publisher","first-page":"4069","DOI":"10.1113\/jphysiol.2008.155077","volume":"586","author":"JJ Alix","year":"2008","unstructured":"Alix JJ, Dolphin AC, Fern R (2008) Vesicular apparatus, including functional calcium channels, are present in developing rodent optic nerve axons and are required for normal node of Ranvier formation. J Physiol 586(17):4069\u20134089","journal-title":"J Physiol"},{"issue":"38","key":"2700_CR161","doi-asserted-by":"publisher","first-page":"11973","DOI":"10.1523\/JNEUROSCI.2927-09.2009","volume":"29","author":"Y Schmitz","year":"2009","unstructured":"Schmitz Y, Luccarelli J, Kim M, Wang M, Sulzer D (2009) Glutamate controls growth rate and branching of dopaminergic axons. J Neurosci 29(38):11973\u201311981","journal-title":"J Neurosci"},{"issue":"9","key":"2700_CR162","doi-asserted-by":"publisher","first-page":"5202","DOI":"10.1523\/JNEUROSCI.14-09-05202.1994","volume":"14","author":"C Aoki","year":"1994","unstructured":"Aoki C, Venkatesan C, Go C, Mong JA, Dawson TM (1994) Cellular and subcellular localization of NMDA-R1 subunit immunoreactivity in the visual cortex of adult and neonatal rats. J Neurosci 14(9):5202\u20135222","journal-title":"J Neurosci"},{"key":"2700_CR163","doi-asserted-by":"publisher","first-page":"540","DOI":"10.3389\/fphys.2019.00540","volume":"10","author":"JE Vaes","year":"2019","unstructured":"Vaes JE, Vink MA, De Theije CG, Hoebeek FE, Benders MJ, Nijboer CH (2019) The potential of stem cell therapy to repair white matter injury in preterm infants: lessons learned from experimental models. Front Physiol 10:540","journal-title":"Front Physiol"},{"issue":"1","key":"2700_CR164","doi-asserted-by":"publisher","first-page":"63","DOI":"10.2174\/157488811794480762","volume":"6","author":"I Kassis","year":"2011","unstructured":"Kassis I, Vaknin-Dembinsky A, Karussis D (2011) Bone marrow mesenchymal stem cells: agents of immunomodulation and neuroprotection. Curr Stem Cell Res Ther 6(1):63\u201368","journal-title":"Curr Stem Cell Res Ther"},{"issue":"9","key":"2700_CR165","doi-asserted-by":"publisher","first-page":"1045","DOI":"10.3727\/096368913X667709","volume":"23","author":"X Liang","year":"2014","unstructured":"Liang X, Ding Y, Zhang Y, Tse H-F, Lian Q (2014) Paracrine mechanisms of mesenchymal stem cell-based therapy: current status and perspectives. Cell Transplant 23(9):1045\u20131059","journal-title":"Cell Transplant"},{"issue":"5","key":"2700_CR166","first-page":"419","volume":"68","author":"CT Van Velthoven","year":"2010","unstructured":"Van Velthoven CT, Kavelaars A, Van Bel F, Heijnen CJ (2010) Nasal administration of stem cells: a promising novel route to treat neonatal ischemic brain damage. Pediatr Res 68(5):419\u2013422","journal-title":"Pediatr Res"},{"key":"2700_CR167","doi-asserted-by":"publisher","first-page":"200","DOI":"10.3389\/fnins.2017.00200","volume":"11","author":"MC Paton","year":"2017","unstructured":"Paton MC, McDonald CA, Allison BJ, Fahey MC, Jenkin G, Miller SL (2017) Perinatal brain injury as a consequence of preterm birth and intrauterine inflammation: designing targeted stem cell therapies. Front Neurosci 11:200","journal-title":"Front Neurosci"},{"issue":"5","key":"2700_CR168","doi-asserted-by":"publisher","first-page":"574","DOI":"10.2174\/156652412800619950","volume":"12","author":"P De Miguel","year":"2012","unstructured":"De Miguel P, M, Fuentes-Julian S, Blazquez-Martinez A, Y Pascual C, A Aller M, Arias J, Arnalich-Montiel F, (2012) Immunosuppressive properties of mesenchymal stem cells: advances and applications. Curr Mol Med 12(5):574\u2013591","journal-title":"Curr Mol Med"},{"issue":"1","key":"2700_CR169","doi-asserted-by":"publisher","first-page":"32","DOI":"10.1038\/icb.2012.64","volume":"91","author":"SA Jacobs","year":"2013","unstructured":"Jacobs SA, Roobrouck VD, Verfaillie CM, Van Gool SW (2013) Immunological characteristics of human mesenchymal stem cells and multipotent adult progenitor cells. Immunol Cell Biol 91(1):32\u201339","journal-title":"Immunol Cell Biol"},{"issue":"4","key":"2700_CR170","doi-asserted-by":"publisher","first-page":"727","DOI":"10.1016\/j.bbrc.2016.10.115","volume":"480","author":"Z Zhang","year":"2016","unstructured":"Zhang Z, Li Z, Deng W, He Q, Wang Q, Shi W, Chen Q, Yang W, Spector M, Gong A (2016) Ectoderm mesenchymal stem cells promote differentiation and maturation of oligodendrocyte precursor cells. Biochem Biophys Res Commun 480(4):727\u2013733","journal-title":"Biochem Biophys Res Commun"},{"issue":"7","key":"2700_CR171","doi-asserted-by":"publisher","first-page":"829","DOI":"10.1016\/j.jcyt.2017.03.075","volume":"19","author":"B Oppliger","year":"2017","unstructured":"Oppliger B, Joerger-Messerli MS, Simillion C, Mueller M, Surbek DV, Schoeberlein A (2017) Mesenchymal stromal cells from umbilical cord Wharton\u2019s jelly trigger oligodendroglial differentiation in neural progenitor cells through cell-to-cell contact. Cytotherapy 19(7):829\u2013838","journal-title":"Cytotherapy"},{"issue":"4","key":"2700_CR172","doi-asserted-by":"publisher","first-page":"275","DOI":"10.1046\/j.1440-1789.2002.00450.x","volume":"22","author":"X Chen","year":"2002","unstructured":"Chen X, Li Y, Wang L, Katakowski M, Zhang L, Chen J, Xu Y, Gautam SC, Chopp M (2002) Ischemic rat brain extracts induce human marrow stromal cell growth factor production. Neuropathology 22(4):275\u2013279","journal-title":"Neuropathology"},{"issue":"10","key":"2700_CR173","doi-asserted-by":"publisher","first-page":"1279","DOI":"10.3727\/096368913X667510","volume":"23","author":"Y Tang","year":"2014","unstructured":"Tang Y, Cai B, Yuan F, He X, Lin X, Wang J, Wang Y, Yang G-Y (2014) Melatonin pretreatment improves the survival and function of transplanted mesenchymal stem cells after focal cerebral ischemia. Cell Transplant 23(10):1279\u20131291","journal-title":"Cell Transplant"},{"issue":"8","key":"2700_CR174","doi-asserted-by":"publisher","first-page":"1489","DOI":"10.3727\/096368916X690430","volume":"25","author":"EH Kim","year":"2016","unstructured":"Kim EH, Kim DH, Kim HR, Kim SY, Kim HH, Bang OY (2016) Stroke serum priming modulates characteristics of mesenchymal stromal cells by controlling the expression miRNA-20a. Cell Transplant 25(8):1489\u20131499","journal-title":"Cell Transplant"},{"issue":"4","key":"2700_CR175","doi-asserted-by":"publisher","first-page":"239","DOI":"10.1089\/scd.2016.0108","volume":"26","author":"M Mueller","year":"2017","unstructured":"Mueller M, Oppliger B, Joerger-Messerli M, Reinhart U, Barnea E, Paidas M, Kramer BW, Surbek DV, Schoeberlein A (2017) Wharton\u2019s jelly mesenchymal stem cells protect the immature brain in rats and modulate cell fate. Stem cells and development 26(4):239\u2013248","journal-title":"Stem cells and development"},{"issue":"16","key":"2700_CR176","doi-asserted-by":"publisher","first-page":"1234","DOI":"10.1089\/scd.2016.0027","volume":"25","author":"B Oppliger","year":"2016","unstructured":"Oppliger B, Joerger-Messerli M, Mueller M, Reinhart U, Schneider P, Surbek DV, Schoeberlein A (2016) Intranasal delivery of umbilical cord-derived mesenchymal stem cells preserves myelination in perinatal brain damage. Stem cells and development 25(16):1234\u20131242","journal-title":"Stem cells and development"},{"key":"2700_CR177","doi-asserted-by":"crossref","unstructured":"Karthik L, Kumar G, Keswani T, Bhattacharyya A, Chandar SS, Bhaskara Rao K (2014) Protease inhibitors from marine actinobacteria as a potential source for antimalarial compound. PloS one 9 (3):e90972","DOI":"10.1371\/journal.pone.0090972"},{"key":"2700_CR178","doi-asserted-by":"publisher","first-page":"205","DOI":"10.1016\/j.expneurol.2016.06.007","volume":"287","author":"M Sandhu","year":"2017","unstructured":"Sandhu M, Ross H, Lee K, Ormerod B, Reier P, Fuller D (2017) Intraspinal transplantation of subventricular zone-derived neural progenitor cells improves phrenic motor output after high cervical spinal cord injury. Exp Neurol 287:205\u2013215","journal-title":"Exp Neurol"},{"issue":"2","key":"2700_CR179","doi-asserted-by":"publisher","first-page":"165","DOI":"10.1038\/s41390-019-0366-z","volume":"86","author":"MC Paton","year":"2019","unstructured":"Paton MC, Allison BJ, Fahey MC, Li J, Sutherland AE, Pham Y, Nitsos I, Bischof RJ, Moss TJ, Polglase GR (2019) Umbilical cord blood versus mesenchymal stem cells for inflammation-induced preterm brain injury in fetal sheep. Pediatr Res 86(2):165\u2013173","journal-title":"Pediatr Res"},{"key":"2700_CR180","doi-asserted-by":"publisher","first-page":"187","DOI":"10.1016\/j.brainres.2008.01.066","volume":"1201","author":"A Chen","year":"2008","unstructured":"Chen A, Dimambro N, Clowry GJ (2008) A comparison of behavioural and histological outcomes of periventricular injection of ibotenic acid in neonatal rats at postnatal days 5 and 7. Brain Res 1201:187\u2013195","journal-title":"Brain Res"},{"issue":"3","key":"2700_CR181","doi-asserted-by":"publisher","first-page":"255","DOI":"10.1016\/j.scr.2010.08.004","volume":"5","author":"A Chen","year":"2010","unstructured":"Chen A, Siow B, Blamire AM, Lako M, Clowry GJ (2010) Transplantation of magnetically labeled mesenchymal stem cells in a model of perinatal brain injury. Stem Cell Research 5(3):255\u2013266","journal-title":"Stem Cell Research"},{"key":"2700_CR182","doi-asserted-by":"publisher","first-page":"13","DOI":"10.1016\/j.brainres.2014.03.030","volume":"1563","author":"L-h Zhu","year":"2014","unstructured":"Zhu L-h, Bai X, Zhang N, Wang S-y, Li W, Jiang L (2014) Improvement of human umbilical cord mesenchymal stem cell transplantation on glial cell and behavioral function in a neonatal model of periventricular white matter damage. Brain Res 1563:13\u201321","journal-title":"Brain Res"},{"issue":"1","key":"2700_CR183","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1186\/s41232-016-0032-3","volume":"37","author":"C Morioka","year":"2017","unstructured":"Morioka C, Komaki M, Taki A, Honda I, Yokoyama N, Iwasaki K, Iseki S, Morio T, Morita I (2017) Neuroprotective effects of human umbilical cord-derived mesenchymal stem cells on periventricular leukomalacia-like brain injury in neonatal rats. Inflammation and regeneration 37(1):1\u201310","journal-title":"Inflammation and regeneration"}],"container-title":["Molecular Neurobiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12035-021-02700-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s12035-021-02700-7\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12035-021-02700-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,10,25]],"date-time":"2022-10-25T19:38:39Z","timestamp":1666726719000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s12035-021-02700-7"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,1,18]]},"references-count":183,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2022,4]]}},"alternative-id":["2700"],"URL":"https:\/\/doi.org\/10.1007\/s12035-021-02700-7","relation":{},"ISSN":["0893-7648","1559-1182"],"issn-type":[{"value":"0893-7648","type":"print"},{"value":"1559-1182","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,1,18]]},"assertion":[{"value":"29 August 2021","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"10 December 2021","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"18 January 2022","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"No animal or human used in this study. All of data were collected from the open scientific and public sources.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Human and Animal Rights"}},{"value":"Not applicable.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to Participate"}},{"value":"Not applicable.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for Publication"}},{"value":"The authors declare no competing interests.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of Interest"}}]}}