{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,3]],"date-time":"2026-11-03T14:51:02Z","timestamp":1793717462845,"version":"4.6.1"},"reference-count":41,"publisher":"Springer Science and Business Media LLC","issue":"5","license":[{"start":{"date-parts":[[2023,1,19]],"date-time":"2023-01-19T00:00:00Z","timestamp":1674086400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2023,1,19]],"date-time":"2023-01-19T00:00:00Z","timestamp":1674086400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Mol Neurobiol"],"published-print":{"date-parts":[[2023,5]]},"DOI":"10.1007\/s12035-023-03222-0","type":"journal-article","created":{"date-parts":[[2023,1,19]],"date-time":"2023-01-19T15:20:09Z","timestamp":1674141609000},"page":"2413-2425","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["METTL3-Mediated N6-Methyladenosine Modification of lncRNA D26496 Suppresses the Proliferation and Migration of Schwann Cells after Sciatic Nerve Injury"],"prefix":"10.1007","volume":"60","author":[{"given":"Xin","family":"He","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jia\u2019nan","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yunshan","family":"Guo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaowei","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yunfei","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6135-5372","authenticated-orcid":false,"given":"Dingjun","family":"Hao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2023,1,19]]},"reference":[{"issue":"4","key":"3222_CR1","doi-asserted-by":"publisher","first-page":"2200","DOI":"10.1007\/s13311-021-01125-3","volume":"18","author":"P Arthur-Farraj","year":"2021","unstructured":"Arthur-Farraj P, Coleman MP (2021) Lessons from injury: how nerve injury studies reveal basic biological mechanisms and therapeutic opportunities for peripheral nerve diseases. Neurotherapeutics\u202f: J Am Soc Exp NeuroTherapeutics 18(4):2200\u20132221. https:\/\/doi.org\/10.1007\/s13311-021-01125-3","journal-title":"Neurotherapeutics : J Am Soc Exp NeuroTherapeutics"},{"issue":"8","key":"3222_CR2","doi-asserted-by":"publisher","first-page":"1518","DOI":"10.4103\/1673-5374.303008","volume":"16","author":"C Li","year":"2021","unstructured":"Li C, Liu SY, Pi W, Zhang PX (2021) Cortical plasticity and nerve regeneration after peripheral nerve injury. Neural Regen Res 16(8):1518\u20131523. https:\/\/doi.org\/10.4103\/1673-5374.303008","journal-title":"Neural Regen Res"},{"key":"3222_CR3","doi-asserted-by":"publisher","unstructured":"Rigoni M, Negro S (2020) Signals orchestrating peripheral nerve repair. Cells 9(8). https:\/\/doi.org\/10.3390\/cells9081768","DOI":"10.3390\/cells9081768"},{"issue":"20","key":"3222_CR4","doi-asserted-by":"publisher","first-page":"3977","DOI":"10.1007\/s00018-020-03516-9","volume":"77","author":"G Nocera","year":"2020","unstructured":"Nocera G, Jacob C (2020) Mechanisms of Schwann cell plasticity involved in peripheral nerve repair after injury. Cell Mol Life Sci: CMLS 77(20):3977\u20133989. https:\/\/doi.org\/10.1007\/s00018-020-03516-9","journal-title":"Cell Mol Life Sci: CMLS"},{"issue":"44","key":"3222_CR5","doi-asserted-by":"publisher","first-page":"22347","DOI":"10.1073\/pnas.1910292116","volume":"116","author":"B Liu","year":"2019","unstructured":"Liu B, Xin W, Tan JR, Zhu RP, Li T, Wang D, Kan SS, Xiong DK et al (2019) Myelin sheath structure and regeneration in peripheral nerve injury repair. Proc Natl Acad Sci USA 116(44):22347\u201322352. https:\/\/doi.org\/10.1073\/pnas.1910292116","journal-title":"Proc Natl Acad Sci USA"},{"key":"3222_CR6","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.neuroscience.2018.04.018","volume":"382","author":"W Lv","year":"2018","unstructured":"Lv W, Deng B, Duan W, Li Y, Liu Y, Li Z, Xia W, Li C (2018) Schwann cell plasticity is regulated by a weakened intrinsic antioxidant defense system in acute peripheral nerve injury. Neuroscience 382:1\u201313. https:\/\/doi.org\/10.1016\/j.neuroscience.2018.04.018","journal-title":"Neuroscience"},{"issue":"3","key":"3222_CR7","doi-asserted-by":"publisher","first-page":"143","DOI":"10.1038\/nrm.2017.104","volume":"19","author":"JD Ransohoff","year":"2018","unstructured":"Ransohoff JD, Wei Y, Khavari PA (2018) The functions and unique features of long intergenic non-coding RNA. Nat Rev Mol Cell Biol 19(3):143\u2013157. https:\/\/doi.org\/10.1038\/nrm.2017.104","journal-title":"Nat Rev Mol Cell Biol"},{"key":"3222_CR8","doi-asserted-by":"publisher","first-page":"127","DOI":"10.1016\/j.mam.2019.07.004","volume":"70","author":"E Hosseini","year":"2019","unstructured":"Hosseini E, Bagheri-Hosseinabadi Z, De Toma I, Jafarisani M, Sadeghi I (2019) The importance of long non-coding RNAs in neuropsychiatric disorders. Mol Aspects Med 70:127\u2013140. https:\/\/doi.org\/10.1016\/j.mam.2019.07.004","journal-title":"Mol Aspects Med"},{"key":"3222_CR9","doi-asserted-by":"publisher","first-page":"1033","DOI":"10.3389\/fgene.2019.01033","volume":"10","author":"SF Zhang","year":"2019","unstructured":"Zhang SF, Gao J, Liu CM (2019) The role of non-coding RNAs in neurodevelopmental disorders. Front Genet 10:1033. https:\/\/doi.org\/10.3389\/fgene.2019.01033","journal-title":"Front Genet"},{"key":"3222_CR10","doi-asserted-by":"publisher","first-page":"117","DOI":"10.1016\/j.neulet.2012.12.014","volume":"534","author":"B Yu","year":"2013","unstructured":"Yu B, Zhou S, Hu W, Qian T, Gao R, Ding G, Ding F, Gu X (2013) Altered long noncoding RNA expressions in dorsal root ganglion after rat sciatic nerve injury. Neurosci Lett 534:117\u2013122. https:\/\/doi.org\/10.1016\/j.neulet.2012.12.014","journal-title":"Neurosci Lett"},{"key":"3222_CR11","doi-asserted-by":"publisher","first-page":"3477","DOI":"10.3892\/ijmm.2018.3571","volume":"41","author":"H Wang","year":"2018","unstructured":"Wang H, Wu J, Zhang X, Ding L, Zeng Q (2018) Microarray analysis of the expression profile of lncRNAs reveals the key role of lncRNA BC088327 as an agonist to heregulin-1\u03b2-induced cell proliferation in peripheral nerve injury. Int J Mol Med 41:3477\u20133484. https:\/\/doi.org\/10.3892\/ijmm.2018.3571","journal-title":"Int J Mol Med"},{"issue":"6","key":"3222_CR12","doi-asserted-by":"publisher","first-page":"1282","DOI":"10.1002\/1878-0261.12676","volume":"14","author":"Y Ban","year":"2020","unstructured":"Ban Y, Tan P, Cai J, Li J, Hu M, Zhou Y, Mei Y, Tan Y et al (2020) LNCAROD is stabilized by m6A methylation and promotes cancer progression via forming a ternary complex with HSPA1A and YBX1 in head and neck squamous cell carcinoma. Mol Oncol 14(6):1282\u20131296. https:\/\/doi.org\/10.1002\/1878-0261.12676","journal-title":"Mol Oncol"},{"issue":"3","key":"3222_CR13","doi-asserted-by":"publisher","first-page":"444","DOI":"10.1038\/cr.2017.10","volume":"27","author":"A Li","year":"2017","unstructured":"Li A, Chen YS, Ping XL, Yang X, Xiao W, Yang Y, Sun HY, Zhu Q et al (2017) Cytoplasmic m 6 A reader YTHDF3 promotes mRNA translation. Cell Res 27(3):444\u2013447. https:\/\/doi.org\/10.1038\/cr.2017.10","journal-title":"Cell Res"},{"issue":"8","key":"3222_CR14","doi-asserted-by":"publisher","first-page":"1419","DOI":"10.1080\/15548627.2019.1586246","volume":"15","author":"H Song","year":"2019","unstructured":"Song H, Feng X, Zhang H, Luo Y, Huang J, Lin M, Jin J, Ding X et al (2019) METTL3 and ALKBH5 oppositely regulate m6A modification of TFEB mRNA, which dictates the fate of hypoxia\/reoxygenation-treated cardiomyocytes. Autophagy 15(8):1419\u20131437. https:\/\/doi.org\/10.1080\/15548627.2019.1586246","journal-title":"Autophagy"},{"issue":"7","key":"3222_CR15","doi-asserted-by":"publisher","first-page":"1187","DOI":"10.1016\/j.cell.2017.05.045","volume":"169","author":"IA Roundtree","year":"2017","unstructured":"Roundtree IA, Evans ME, Pan T, He C (2017) Dynamic RNA modifications in gene expression regulation. Cell 169(7):1187\u20131200. https:\/\/doi.org\/10.1016\/j.cell.2017.05.045","journal-title":"Cell"},{"issue":"1","key":"3222_CR16","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1186\/s12943-019-1033-z","volume":"18","author":"XY Chen","year":"2019","unstructured":"Chen XY, Zhang J, Zhu JS (2019) The role of m6A RNA methylation in human cancer. Mol Cancer 18(1):1\u20139. https:\/\/doi.org\/10.1186\/s12943-019-1033-z","journal-title":"Mol Cancer"},{"issue":"7","key":"3222_CR17","doi-asserted-by":"publisher","first-page":"1285","DOI":"10.1158\/0008-5472","volume":"79","author":"Q Lan","year":"2019","unstructured":"Lan Q, Liu PY, Haase J, Bell JL, H\u00fcttelmaier S, Liu T (2019) The critical role of RNA m6A methylation in cancer. Can Res 79(7):1285\u20131292. https:\/\/doi.org\/10.1158\/0008-5472","journal-title":"Can Res"},{"key":"3222_CR18","doi-asserted-by":"publisher","first-page":"686000","DOI":"10.3389\/fgene.2021.686000","volume":"12","author":"L Zhang","year":"2021","unstructured":"Zhang L, Hao D, Ma P, Ma B, Qin J, Tian G, Liu Z, Zhou X (2021) Epitranscriptomic analysis of m6A methylome after peripheral nerve injury. Front Genet 12:686000. https:\/\/doi.org\/10.3389\/fgene.2021.686000","journal-title":"Front Genet"},{"key":"3222_CR19","doi-asserted-by":"publisher","DOI":"10.18388\/abp.2020_6185","author":"SF Wu","year":"2022","unstructured":"Wu SF, Wang Y, Zhao QC (2022) Demethylase FTO promotes neuropathic pain development via regulating the m6A methylation levels of CXCR3. Acta Biochim Polonica. https:\/\/doi.org\/10.18388\/abp.2020_6185","journal-title":"Acta Biochim Polonica"},{"key":"3222_CR20","doi-asserted-by":"publisher","first-page":"7891202","DOI":"10.1155\/2016\/7891202","volume":"2016","author":"Y Chen","year":"2016","unstructured":"Chen Y, Guo W, Xu L, Li W, Cheng M, Hu Y, Xu W (2016) 17\u03b2-Estradiol promotes Schwann cell proliferation and differentiation, accelerating early remyelination in a mouse peripheral nerve injury model. Biomed Res Int 2016:7891202. https:\/\/doi.org\/10.1155\/2016\/7891202","journal-title":"Biomed Res Int"},{"key":"3222_CR21","doi-asserted-by":"publisher","DOI":"10.1002\/jcp.28302","author":"X Liu","year":"2019","unstructured":"Liu X, Yu X, He Y, Wang L (2019) Long noncoding RNA nuclear enriched abundant transcript 1 promotes the proliferation and migration of Schwann cells by regulating the miR-34a\/Satb1 axis. J Cell Physiol. https:\/\/doi.org\/10.1002\/jcp.28302","journal-title":"J Cell Physiol"},{"issue":"6","key":"3222_CR22","doi-asserted-by":"publisher","first-page":"2254","DOI":"10.1002\/hep.29683","volume":"67","author":"M Chen","year":"2018","unstructured":"Chen M, Wei L, Law CT, Tsang FH, Shen J, Cheng CL, Tsang LH, Ho DW et al (2018) RNA N6-methyladenosine methyltransferase-like 3 promotes liver cancer progression through YTHDF2-dependent posttranscriptional silencing of SOCS2. Hepatology (Baltimore, MD) 67(6):2254\u20132270. https:\/\/doi.org\/10.1002\/hep.29683","journal-title":"Hepatology (Baltimore, MD)"},{"key":"3222_CR23","doi-asserted-by":"publisher","first-page":"6657944","DOI":"10.1155\/2021\/6657944","volume":"2021","author":"Z Zhou","year":"2021","unstructured":"Zhou Z, Qi D, Gan Q, Wang F, Qin B, Li J, Wang H, Wang D (2021) Studies on the regulatory roles and related mechanisms of lncRNAs in the nervous system. Oxid Med Cell Longev 2021:6657944. https:\/\/doi.org\/10.1155\/2021\/6657944","journal-title":"Oxid Med Cell Longev"},{"issue":"1","key":"3222_CR24","doi-asserted-by":"publisher","first-page":"34","DOI":"10.1186\/s13058-020-01269-8","volume":"22","author":"MT Haider","year":"2020","unstructured":"Haider MT, Saito H, Zarrer J, Uzhunnumpuram K, Nagarajan S, Kari V, Horn-Glander M, Werner S et al (2020) Breast cancer bone metastases are attenuated in a Tgif1-deficient bone microenvironment. Breast Cancer Res: BCR 22(1):34. https:\/\/doi.org\/10.1186\/s13058-020-01269-8","journal-title":"Breast Cancer Res: BCR"},{"issue":"29","key":"3222_CR25","doi-asserted-by":"publisher","first-page":"6574","DOI":"10.1523\/JNEUROSCI.3790-16.2018","volume":"38","author":"C Yao","year":"2018","unstructured":"Yao C, Wang Y, Zhang H, Feng W, Wang Q, Shen D, Qian T, Liu F et al (2018) lncRNA TNXA-PS1 modulates Schwann cells by functioning as a competing endogenous RNA following nerve injury. J Neurosci 38(29):6574\u20136585. https:\/\/doi.org\/10.1523\/JNEUROSCI.3790-16.2018","journal-title":"J Neurosci"},{"issue":"3","key":"3222_CR26","doi-asserted-by":"publisher","first-page":"670","DOI":"10.1002\/glia.23749","volume":"68","author":"C Yao","year":"2020","unstructured":"Yao C, Chen Y, Wang J, Qian T, Feng W, Chen Y, Mao S, Yu B (2020) LncRNA BC088259 promotes Schwann cell migration through Vimentin following peripheral nerve injury. Glia 68(3):670\u2013679. https:\/\/doi.org\/10.1002\/glia.23749","journal-title":"Glia"},{"issue":"22","key":"3222_CR27","doi-asserted-by":"publisher","first-page":"680","DOI":"10.21037\/atm.2019.11.18","volume":"7","author":"J Qiu","year":"2019","unstructured":"Qiu J, Yang X, Wang L, Zhang Q, Ma W, Huang Z, Bao Y, Zhong L et al (2019) Isoquercitrin promotes peripheral nerve regeneration through inhibiting oxidative stress following sciatic crush injury in mice. Ann Transl Med 7(22):680. https:\/\/doi.org\/10.21037\/atm.2019.11.18","journal-title":"Ann Transl Med"},{"key":"3222_CR28","doi-asserted-by":"publisher","first-page":"175909141983894","DOI":"10.1177\/1759091419838949","volume":"11","author":"M Kim","year":"2019","unstructured":"Kim M, Kim H, Kim D, Kim D, Huh Y, Park C, Chung HJ, Jung J et al (2019) Heme oxygenase 1 in Schwann cells regulates peripheral nerve degeneration against oxidative stress. ASN Neuro 11:1759091419838949. https:\/\/doi.org\/10.1177\/1759091419838949","journal-title":"ASN Neuro"},{"issue":"8","key":"3222_CR29","doi-asserted-by":"publisher","first-page":"4592","DOI":"10.1002\/ptr.7177","volume":"35","author":"L Chen","year":"2021","unstructured":"Chen L, Chen Z, Xu Z, Feng W, Yang X, Qi Z (2021) Polydatin protects Schwann cells from methylglyoxal induced cytotoxicity and promotes crushed sciatic nerves regeneration of diabetic rats. Phytother Res: PTR 35(8):4592\u20134604. https:\/\/doi.org\/10.1002\/ptr.7177","journal-title":"Phytother Res: PTR"},{"issue":"23","key":"3222_CR30","doi-asserted-by":"publisher","first-page":"11463","DOI":"10.18632\/aging.102545","volume":"11","author":"J Sun","year":"2019","unstructured":"Sun J, Zheng J, Li Y, Yan M, Li P, Ma L (2019) LncRNA EPIC1 downregulation mediates hydrogen peroxide-induced neuronal cell injury. Aging (Albany NY) 11(23):11463. https:\/\/doi.org\/10.18632\/aging.102545","journal-title":"Aging (Albany NY)"},{"issue":"43","key":"3222_CR31","doi-asserted-by":"publisher","first-page":"6664","DOI":"10.1038\/s41388-020-01460-3","volume":"39","author":"J Yuan","year":"2020","unstructured":"Yuan J, Song Y, Pan W, Li Y, Xu Y, Xie M, Shen Y, Zhang N et al (2020) LncRNA SLC26A4-AS1 suppresses the MRN complex-mediated DNA repair signaling and thyroid cancer metastasis by destabilizing DDX5. Oncogene 39(43):6664\u20136676. https:\/\/doi.org\/10.1038\/s41388-020-01460-3","journal-title":"Oncogene"},{"issue":"1","key":"3222_CR32","doi-asserted-by":"publisher","first-page":"87","DOI":"10.1186\/s12943-019-1014-2","volume":"18","author":"Y Wu","year":"2019","unstructured":"Wu Y, Yang X, Chen Z, Tian L, Jiang G, Chen F, Li J, An P et al (2019) m(6)A-induced lncRNA RP11 triggers the dissemination of colorectal cancer cells via upregulation of Zeb1. Mol Cancer 18(1):87. https:\/\/doi.org\/10.1186\/s12943-019-1014-2","journal-title":"Mol Cancer"},{"issue":"1","key":"3222_CR33","doi-asserted-by":"publisher","first-page":"34","DOI":"10.1186\/s12935-020-1105-6","volume":"20","author":"S Chen","year":"2020","unstructured":"Chen S, Zhou L, Wang Y (2020) ALKBH5-mediated m6A demethylation of lncRNA PVT1 plays an oncogenic role in osteosarcoma. Cancer Cell Int 20(1):34\u201343. https:\/\/doi.org\/10.1186\/s12935-020-1105-6","journal-title":"Cancer Cell Int"},{"key":"3222_CR34","doi-asserted-by":"publisher","unstructured":"Liang J, Zhang S, Wang W, Xu Y, Kawuli A, Lu J, Xiu X (2020) Long non-coding RNA DSCAM-AS1 contributes to the tumorigenesis of cervical cancer by targeting miR-877-5p\/ATXN7L3 axis. Biosci Rep 40(1). https:\/\/doi.org\/10.1042\/bsr20192061","DOI":"10.1042\/bsr20192061"},{"issue":"6","key":"3222_CR35","first-page":"1631","volume":"10","author":"S Liu","year":"2020","unstructured":"Liu S, Zhuo L, Wang J, Zhang Q, Li Q, Li G, Yan L, Jin T et al (2020) METTL3 plays multiple functions in biological processes. Am J Cancer Res 10(6):1631\u20131646","journal-title":"Am J Cancer Res"},{"issue":"1","key":"3222_CR36","doi-asserted-by":"publisher","first-page":"117","DOI":"10.1186\/s13045-020-00951-w","volume":"13","author":"C Zeng","year":"2020","unstructured":"Zeng C, Huang W, Li Y, Weng H (2020) Roles of METTL3 in cancer: mechanisms and therapeutic targeting. J Hematol Oncol 13(1):117. https:\/\/doi.org\/10.1186\/s13045-020-00951-w","journal-title":"J Hematol Oncol"},{"issue":"7849","key":"3222_CR37","doi-asserted-by":"publisher","first-page":"317","DOI":"10.1038\/s41586-021-03210-1","volume":"591","author":"W Xu","year":"2021","unstructured":"Xu W, Li J, He C, Wen J, Ma H, Rong B, Diao J, Wang L et al (2021) METTL3 regulates heterochromatin in mouse embryonic stem cells. Nature 591(7849):317\u2013321. https:\/\/doi.org\/10.1038\/s41586-021-03210-1","journal-title":"Nature"},{"issue":"1","key":"3222_CR38","doi-asserted-by":"publisher","first-page":"163","DOI":"10.1186\/s12943-019-1082-3","volume":"18","author":"J Hou","year":"2019","unstructured":"Hou J, Zhang H, Liu J, Zhao Z, Wang J, Lu Z, Hu B, Zhou J, Zhao Z et al (2019) YTHDF2 reduction fuels inflammation and vascular abnormalization in hepatocellular carcinoma. Mol Cancer 18(1):163. https:\/\/doi.org\/10.1186\/s12943-019-1082-3","journal-title":"Mol Cancer"},{"issue":"6","key":"3222_CR39","doi-asserted-by":"publisher","first-page":"1323","DOI":"10.3390\/ijms20061323","volume":"20","author":"R Yu","year":"2019","unstructured":"Yu R, Li Q, Feng Z, Cai L, Xu Q (2019) m6A reader YTHDF2 regulates LPS-induced inflammatory response. Int J Mol Sci 20(6):1323. https:\/\/doi.org\/10.3390\/ijms20061323","journal-title":"Int J Mol Sci"},{"issue":"1","key":"3222_CR40","doi-asserted-by":"publisher","first-page":"69","DOI":"10.1186\/s13059-018-1436-y","volume":"19","author":"M Li","year":"2018","unstructured":"Li M, Zhao X, Wang W, Shi H, Pan Q, Lu Z, Perez SP, Suganthan R et al (2018) Ythdf2-mediated m(6)A mRNA clearance modulates neural development in mice. Genome Biol 19(1):69. https:\/\/doi.org\/10.1186\/s13059-018-1436-y","journal-title":"Genome Biol"},{"issue":"1","key":"3222_CR41","doi-asserted-by":"publisher","first-page":"132","DOI":"10.1186\/s13578-021-00649-7","volume":"11","author":"H Xu","year":"2021","unstructured":"Xu H, Wang Z, Chen M, Zhao W, Tao T, Ma L, Ni Y, Li W (2021) YTHDF2 alleviates cardiac hypertrophy via regulating Myh7 mRNA decoy. Cell Biosci 11(1):132. https:\/\/doi.org\/10.1186\/s13578-021-00649-7","journal-title":"Cell Biosci"}],"container-title":["Molecular Neurobiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12035-023-03222-0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s12035-023-03222-0\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12035-023-03222-0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,3,25]],"date-time":"2023-03-25T11:19:42Z","timestamp":1679743182000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s12035-023-03222-0"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,1,19]]},"references-count":41,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2023,5]]}},"alternative-id":["3222"],"URL":"https:\/\/doi.org\/10.1007\/s12035-023-03222-0","relation":{},"ISSN":["0893-7648","1559-1182"],"issn-type":[{"value":"0893-7648","type":"print"},{"value":"1559-1182","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,1,19]]},"assertion":[{"value":"13 June 2022","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"4 January 2023","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"19 January 2023","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The present study and the associated experimental protocols were performed in compliance with ethical guidelines and approved by the Ethics Committee of Hong Hui Hospital.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics Approval"}},{"value":"All authors approved the manuscript for publication.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for Publication"}},{"value":"The authors declare no competing interests.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing Interests"}}]}}