{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T16:14:46Z","timestamp":1791994486171,"version":"4.4.0"},"reference-count":72,"publisher":"Springer Science and Business Media LLC","issue":"6","license":[{"start":{"date-parts":[[2023,3,6]],"date-time":"2023-03-06T00:00:00Z","timestamp":1678060800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2023,3,6]],"date-time":"2023-03-06T00:00:00Z","timestamp":1678060800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Mol Neurobiol"],"published-print":{"date-parts":[[2023,6]]},"DOI":"10.1007\/s12035-023-03261-7","type":"journal-article","created":{"date-parts":[[2023,3,6]],"date-time":"2023-03-06T12:06:34Z","timestamp":1678104394000},"page":"3464-3485","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":35,"title":["Doublecortin-Expressing Neurons in Human Cerebral Cortex Layer II and Amygdala from Infancy to 100 Years Old"],"prefix":"10.1007","volume":"60","author":[{"given":"Ya-Nan","family":"Li","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dan-Dan","family":"Hu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiao-Lu","family":"Cai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yan","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chen","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juan","family":"Jiang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qi-Lei","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tian","family":"Tu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiao-Sheng","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hui","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ewen","family":"Tu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiao-Ping","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aihua","family":"Pan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiao-Xin","family":"Yan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4250-6811","authenticated-orcid":false,"given":"Lily","family":"Wan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2023,3,6]]},"reference":[{"issue":"1","key":"3261_CR1","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.pneurobio.2012.05.002","volume":"98","author":"L Bonfanti","year":"2012","unstructured":"Bonfanti L, Nacher J (2012) New scenarios for neuronal structural plasticity in non-neurogenic brain parenchyma: the case of cortical layer II immature neurons. Prog Neurobiol 98(1):1\u201315","journal-title":"Prog Neurobiol"},{"key":"3261_CR2","doi-asserted-by":"publisher","first-page":"75","DOI":"10.3389\/fnins.2020.00075","volume":"14","author":"C La Rosa","year":"2020","unstructured":"La Rosa C, Parolisi R, Bonfanti L (2020) Brain structural plasticity: from adult neurogenesis to immature neurons. Front Neurosci 14:75","journal-title":"Front Neurosci"},{"key":"3261_CR3","doi-asserted-by":"crossref","unstructured":"Kim JY, Paredes MF (2021) Implications of extended inhibitory neuron development. Int J Mol Sci 22(10):5113","DOI":"10.3390\/ijms22105113"},{"key":"3261_CR4","doi-asserted-by":"crossref","unstructured":"Bonfanti L, Seki T (2021) The PSA-NCAM-positive \u201cimmature\u201d neurons: an old discovery providing new vistas on brain structural plasticity. Cells 10(10):2542","DOI":"10.3390\/cells10102542"},{"issue":"4","key":"3261_CR5","doi-asserted-by":"publisher","first-page":"395","DOI":"10.1007\/BF00957900","volume":"184","author":"T Seki","year":"1991","unstructured":"Seki T, Arai Y (1991) Expression of highly polysialylated NCAM in the neocortex and piriform cortex of the developing and the adult rat. Anat Embryol (Berl) 184(4):395\u2013401","journal-title":"Anat Embryol (Berl)"},{"issue":"2","key":"3261_CR6","doi-asserted-by":"publisher","first-page":"419","DOI":"10.1016\/0306-4522(92)90107-D","volume":"49","author":"L Bonfanti","year":"1992","unstructured":"Bonfanti L, Olive S, Poulain DA, Theodosis DT (1992) Mapping of the distribution of polysialylated neural cell adhesion molecule throughout the central nervous system of the adult rat: an immunohistochemical study. Neuroscience 49(2):419\u2013436","journal-title":"Neuroscience"},{"issue":"7","key":"3261_CR7","doi-asserted-by":"publisher","first-page":"2486","DOI":"10.1523\/JNEUROSCI.18-07-02486.1998","volume":"18","author":"PJ Bernier","year":"1998","unstructured":"Bernier PJ, Parent A (1998) Bcl-2 protein as a marker of neuronal immaturity in postnatal primate brain. J Neurosci 18(7):2486\u20132497","journal-title":"J Neurosci"},{"issue":"3","key":"3261_CR8","doi-asserted-by":"publisher","first-page":"135","DOI":"10.1002\/1097-4695(20001115)45:3<135::AID-NEU1>3.0.CO;2-#","volume":"45","author":"GB Fox","year":"2000","unstructured":"Fox GB, Fichera G, Barry T, O\u2019Connell AW, Gallagher HC, Murphy KJ, Regan CM (2000) Consolidation of passive avoidance learning is associated with transient increases of polysialylated neurons in layer II of the rat medial temporal cortex. J Neurobiol 45(3):135\u2013141","journal-title":"J Neurobiol"},{"issue":"4","key":"3261_CR9","doi-asserted-by":"publisher","first-page":"629","DOI":"10.1046\/j.0953-816x.2001.01683.x","volume":"14","author":"J Nacher","year":"2001","unstructured":"Nacher J, Crespo C, McEwen BS (2001) Doublecortin expression in the adult rat telencephalon. Eur J Neurosci 14(4):629\u2013644","journal-title":"Eur J Neurosci"},{"issue":"17","key":"3261_CR10","doi-asserted-by":"publisher","first-page":"11464","DOI":"10.1073\/pnas.172403999","volume":"99","author":"PJ Bernier","year":"2002","unstructured":"Bernier PJ, Bedard A, Vinet J, Levesque M, Parent A (2002) Newly generated neurons in the amygdala and adjoining cortex of adult primates. Proc Natl Acad Sci U S A 99(17):11464\u201311469","journal-title":"Proc Natl Acad Sci U S A"},{"issue":"2","key":"3261_CR11","doi-asserted-by":"publisher","first-page":"539","DOI":"10.1016\/j.neuroscience.2004.05.019","volume":"127","author":"JL Fudge","year":"2004","unstructured":"Fudge JL (2004) Bcl-2 immunoreactive neurons are differentially distributed in subregions of the amygdala and hippocampus of the adult macaque. Neuroscience 127(2):539\u2013556","journal-title":"Neuroscience"},{"key":"3261_CR12","doi-asserted-by":"publisher","first-page":"104","DOI":"10.1016\/j.neuroscience.2012.03.040","volume":"212","author":"JL Fudge","year":"2012","unstructured":"Fudge JL, deCampo DM, Becoats KT (2012) Revisiting the hippocampal-amygdala pathway in primates: association with immature-appearing neurons. Neuroscience 212:104\u2013119","journal-title":"Neuroscience"},{"issue":"1","key":"3261_CR13","doi-asserted-by":"publisher","first-page":"271","DOI":"10.1016\/j.expneurol.2008.02.003","volume":"211","author":"K Xiong","year":"2008","unstructured":"Xiong K, Luo DW, Patrylo PR, Luo XG, Struble RG, Clough RW, Yan XX (2008) Doublecortin-expressing cells are present in layer II across the adult guinea pig cerebral cortex: partial colocalization with mature interneuron markers. Exp Neurol 211(1):271\u2013282","journal-title":"Exp Neurol"},{"issue":"2","key":"3261_CR14","doi-asserted-by":"publisher","first-page":"342","DOI":"10.1016\/j.expneurol.2008.12.008","volume":"216","author":"Y Cai","year":"2009","unstructured":"Cai Y, Xiong K, Chu Y, Luo DW, Luo XG, Yuan XY, Struble RG, Clough RW et al (2009) Doublecortin expression in adult cat and primate cerebral cortex relates to immature neurons that develop into GABAergic subgroups. Exp Neurol 216(2):342\u2013356","journal-title":"Exp Neurol"},{"issue":"5","key":"3261_CR15","doi-asserted-by":"publisher","first-page":"1028","DOI":"10.1093\/cercor\/bhn145","volume":"19","author":"F Luzzati","year":"2009","unstructured":"Luzzati F, Bonfanti L, Fasolo A, Peretto P (2009) DCX and PSA-NCAM expression identifies a population of neurons preferentially distributed in associative areas of different pallial derivatives and vertebrate species. Cereb Cortex 19(5):1028\u20131041","journal-title":"Cereb Cortex"},{"key":"3261_CR16","doi-asserted-by":"publisher","first-page":"17","DOI":"10.3389\/neuro.05.017.2009","volume":"3","author":"XM Zhang","year":"2009","unstructured":"Zhang XM, Cai Y, Chu Y, Chen EY, Feng JC, Luo XG, Xiong K, Struble RG et al (2009) Doublecortin-expressing cells persist in the associative cerebral cortex and amygdala in aged nonhuman primates. Front Neuroanat 3:17","journal-title":"Front Neuroanat"},{"issue":"2","key":"3261_CR17","doi-asserted-by":"publisher","first-page":"291","DOI":"10.1016\/j.expneurol.2011.05.008","volume":"230","author":"MW Marlatt","year":"2011","unstructured":"Marlatt MW, Philippens I, Manders E, Cz\u00e9h B, Joels M, Krugers H, Lucassen PJ (2011) Distinct structural plasticity in the hippocampus and amygdala of the middle-aged common marmoset (Callithrix jacchus). Exp Neurol 230(2):291\u2013301","journal-title":"Exp Neurol"},{"issue":"1","key":"3261_CR18","doi-asserted-by":"publisher","first-page":"e9","DOI":"10.4081\/ejh.2013.e9","volume":"57","author":"E De Nevi","year":"2013","unstructured":"De Nevi E, Marco-Salazar P, Fondevila D, Blasco E, P\u00e9rez L, Pumarola M (2013) Immunohistochemical study of doublecortin and nucleostemin in canine brain. Eur J Histochem 57(1):e9","journal-title":"Eur J Histochem"},{"issue":"1","key":"3261_CR19","doi-asserted-by":"publisher","first-page":"10","DOI":"10.1111\/ejn.12016","volume":"37","author":"U Mart\u00ed-Mengual","year":"2013","unstructured":"Mart\u00ed-Mengual U, Varea E, Crespo C, Blasco-Ib\u00e1\u00f1ez JM, Nacher J (2013) Cells expressing markers of immature neurons in the amygdala of adult humans. Eur J Neurosci 37(1):10\u201322","journal-title":"Eur J Neurosci"},{"issue":"3","key":"3261_CR20","doi-asserted-by":"publisher","first-page":"227","DOI":"10.1159\/000367934","volume":"84","author":"N Patzke","year":"2014","unstructured":"Patzke N, LeRoy A, Ngubane NW, Bennett NC, Medger K, Gravett N, Kaswera-Kyamakya C, Gilissen E et al (2014) The distribution of doublecortin-immunopositive cells in the brains of four afrotherian mammals: the Hottentot golden mole (Amblysomus hottentotus), the rock hyrax (Procavia capensis), the eastern rock sengi (Elephantulus myurus) and the four-toed sengi (Petrodromus tetradactylus). Brain Behav Evol 84(3):227\u2013241","journal-title":"Brain Behav Evol"},{"issue":"11","key":"3261_CR21","doi-asserted-by":"publisher","first-page":"2254","DOI":"10.1111\/j.1460-9568.2008.06518.x","volume":"28","author":"YW Liu","year":"2008","unstructured":"Liu YW, Curtis MA, Gibbons HM, Mee EW, Bergin PS, Teoh HH, Connor B, Dragunow M et al (2008) Doublecortin expression in the normal and epileptic adult human brain. Eur J Neurosci 28(11):2254\u20132265","journal-title":"Eur J Neurosci"},{"issue":"4","key":"3261_CR22","doi-asserted-by":"publisher","first-page":"826","DOI":"10.1523\/JNEUROSCI.1781-17.2017","volume":"38","author":"M Piumatti","year":"2018","unstructured":"Piumatti M, Palazzo O, La Rosa C, Crociara P, Parolisi R, Luzzati F, L\u00e9vy F, Bonfanti L (2018) Non-newly generated, \u201cimmature\u201d neurons in the sheep brain are not restricted to cerebral cortex. J Neurosci 38(4):826\u2013842","journal-title":"J Neurosci"},{"issue":"1","key":"3261_CR23","doi-asserted-by":"publisher","first-page":"2748","DOI":"10.1038\/s41467-019-10765-1","volume":"10","author":"SF Sorrells","year":"2019","unstructured":"Sorrells SF, Paredes MF, Velmeshev D, Herranz-P\u00e9rez V, Sandoval K, Mayer S, Chang EF, Insausti R et al (2019) Immature excitatory neurons develop during adolescence in the human amygdala. Nat Commun 10(1):2748","journal-title":"Nat Commun"},{"key":"3261_CR24","doi-asserted-by":"publisher","first-page":"727883","DOI":"10.3389\/fnana.2021.727883","volume":"15","author":"JQ Ai","year":"2021","unstructured":"Ai JQ, Luo R, Tu T, Yang C, Jiang J, Zhang B, Bi R, Tu E et al (2021) Doublecortin-expressing neurons in Chinese tree shrew forebrain exhibit mixed rodent and primate-like topographic characteristics. Front Neuroanat 15:727883","journal-title":"Front Neuroanat"},{"key":"3261_CR25","doi-asserted-by":"publisher","first-page":"656882","DOI":"10.3389\/fnana.2021.656882","volume":"15","author":"T van Groen","year":"2021","unstructured":"van Groen T, Kadish I, Popovi\u0107 N, Caballero Bleda M, Ba\u00f1o-Otalora B, Rol MA, Madrid JA, Popovi\u0107 M (2021) Widespread doublecortin expression in the cerebral cortex of the Octodon degus. Front Neuroanat 15:656882","journal-title":"Front Neuroanat"},{"issue":"11","key":"3261_CR26","doi-asserted-by":"publisher","first-page":"1548","DOI":"10.1002\/ar.23460","volume":"299","author":"R Chawana","year":"2016","unstructured":"Chawana R, Patzke N, Alagaili AN, Bennett NC, Mohammed OB, Kaswera-Kyamakya C, Gilissen E, Ihunwo AO et al (2016) The distribution of Ki-67 and doublecortin immunopositive cells in the brains of three Microchiropteran species, Hipposideros fuliginosus, Triaenops persicus, and Asellia tridens. Anat Rec (Hoboken) 299(11):1548\u20131560","journal-title":"Anat Rec (Hoboken)"},{"key":"3261_CR27","doi-asserted-by":"publisher","first-page":"46","DOI":"10.1016\/j.neuroscience.2017.12.037","volume":"372","author":"TM Fasemore","year":"2018","unstructured":"Fasemore TM, Patzke N, Kaswera-Kyamakya C, Gilissen E, Manger PR, Ihunwo AO (2018) The distribution of Ki-67 and doublecortin-immunopositive cells in the brains of three Strepsirrhine Primates: Galago demidoff, Perodicticus potto, and Lemur catta. Neuroscience 372:46\u201357","journal-title":"Neuroscience"},{"key":"3261_CR28","doi-asserted-by":"crossref","unstructured":"La Rosa C, Cavallo F, Pecora A, Chincarini M, Ala U, Faulkes CG, Nacher J, Cozzi B, et al. (2020) Phylogenetic variation in cortical layer II immature neuron reservoir of mammals. Elife 9","DOI":"10.7554\/eLife.55456"},{"issue":"7","key":"3261_CR29","doi-asserted-by":"publisher","first-page":"2610","DOI":"10.1093\/cercor\/bhy087","volume":"28","author":"P Rotheneichner","year":"2018","unstructured":"Rotheneichner P, Belles M, Benedetti B, K\u00f6nig R, Dannehl D, Kreutzer C, Zaunmair P, Engelhardt M et al (2018) Cellular plasticity in the adult murine piriform cortex: continuous maturation of dormant precursors into excitatory neurons. Cereb Cortex 28(7):2610\u20132621","journal-title":"Cereb Cortex"},{"issue":"3","key":"3261_CR30","doi-asserted-by":"publisher","first-page":"1499","DOI":"10.1093\/cercor\/bhz181","volume":"30","author":"B Benedetti","year":"2020","unstructured":"Benedetti B, Dannehl D, K\u00f6nig R, Coviello S, Kreutzer C, Zaunmair P, Jakubecova D, Weiger TM et al (2020) functional integration of neuronal precursors in the adult murine piriform cortex. Cereb Cortex 30(3):1499\u20131515","journal-title":"Cereb Cortex"},{"issue":"2","key":"3261_CR31","doi-asserted-by":"publisher","first-page":"180","DOI":"10.1016\/j.mcn.2010.06.009","volume":"45","author":"K Xiong","year":"2010","unstructured":"Xiong K, Cai Y, Zhang XM, Huang JF, Liu ZY, Fu GM, Feng JC, Clough RW et al (2010) Layer I as a putative neurogenic niche in young adult guinea pig cerebrum. Mol Cell Neurosci 45(2):180\u2013191","journal-title":"Mol Cell Neurosci"},{"key":"3261_CR32","doi-asserted-by":"publisher","first-page":"101","DOI":"10.1016\/j.neuroscience.2013.11.056","volume":"259","author":"X He","year":"2014","unstructured":"He X, Zhang XM, Wu J, Fu J, Mou L, Lu DH, Cai Y, Luo XG et al (2014) Olfactory experience modulates immature neuron development in postnatal and adult guinea pig piriform cortex. Neuroscience 259:101\u2013112","journal-title":"Neuroscience"},{"issue":"13","key":"3261_CR33","doi-asserted-by":"publisher","first-page":"1006","DOI":"10.1097\/WNR.0000000000000203","volume":"25","author":"SL Rossi","year":"2014","unstructured":"Rossi SL, Mahairaki V, Zhou L, Song Y, Koliatsos VE (2014) Remodeling of the piriform cortex after lesion in adult rodents. NeuroReport 25(13):1006\u20131012","journal-title":"NeuroReport"},{"issue":"12","key":"3261_CR34","doi-asserted-by":"publisher","first-page":"2619","DOI":"10.1111\/j.1528-1167.2009.02194.x","volume":"50","author":"N Srikandarajah","year":"2009","unstructured":"Srikandarajah N, Martinian L, Sisodiya SM, Squier W, Blumcke I, Aronica E, Thom M (2009) Doublecortin expression in focal cortical dysplasia in epilepsy. Epilepsia 50(12):2619\u20132628","journal-title":"Epilepsia"},{"issue":"2","key":"3261_CR35","doi-asserted-by":"publisher","first-page":"135","DOI":"10.1111\/neup.12445","volume":"38","author":"M Sakurai","year":"2018","unstructured":"Sakurai M, Suzuki H, Tomita N, Sunden Y, Shimada A, Miyata H, Morita T (2018) Enhanced neurogenesis and possible synaptic reorganization in the piriform cortex of adult rat following kainic acid-induced status epilepticus. Neuropathology 38(2):135\u2013143","journal-title":"Neuropathology"},{"issue":"1","key":"3261_CR36","doi-asserted-by":"publisher","first-page":"53","DOI":"10.1001\/archgenpsychiatry.2011.145","volume":"69","author":"CW Nordahl","year":"2012","unstructured":"Nordahl CW, Scholz R, Yang X, Buonocore MH, Simon T, Rogers S, Amaral DG (2012) Increased rate of amygdala growth in children aged 2 to 4 years with autism spectrum disorders: a longitudinal study. Arch Gen Psychiatry 69(1):53\u201361","journal-title":"Arch Gen Psychiatry"},{"issue":"3","key":"3261_CR37","doi-asserted-by":"publisher","first-page":"384","DOI":"10.1016\/j.jpsychires.2012.11.013","volume":"47","author":"ME Maheu","year":"2013","unstructured":"Maheu ME, Davoli MA, Turecki G, Mechawar N (2013) Amygdalar expression of proteins associated with neuroplasticity in major depression and suicide. J Psychiatr Res 47(3):384\u2013390","journal-title":"J Psychiatr Res"},{"issue":"14","key":"3261_CR38","doi-asserted-by":"publisher","first-page":"3710","DOI":"10.1073\/pnas.1801912115","volume":"115","author":"TA Avino","year":"2018","unstructured":"Avino TA, Barger N, Vargas MV, Carlson EL, Amaral DG, Bauman MD, Schumann CM (2018) Neuron numbers increase in the human amygdala from birth to adulthood, but not in autism. Proc Natl Acad Sci U S A 115(14):3710\u20133715","journal-title":"Proc Natl Acad Sci U S A"},{"issue":"18","key":"3261_CR39","doi-asserted-by":"publisher","first-page":"3034","DOI":"10.1002\/cne.24728","volume":"527","author":"CM Schumann","year":"2019","unstructured":"Schumann CM, Scott JA, Lee A, Bauman MD, Amaral DG (2019) Amygdala growth from youth to adulthood in the macaque monkey. J Comp Neurol 527(18):3034\u20133045","journal-title":"J Comp Neurol"},{"issue":"6","key":"3261_CR40","doi-asserted-by":"publisher","first-page":"923","DOI":"10.1002\/ana.410440611","volume":"44","author":"M Mikkonen","year":"1998","unstructured":"Mikkonen M, Soininen H, K\u00e4lvi\u00e4nen R, Tapiola T, Ylinen A, Vapalahti M, Palj\u00e4rvi L, Pitk\u00e4nen A (1998) Remodeling of neuronal circuitries in human temporal lobe epilepsy: increased expression of highly polysialylated neural cell adhesion molecule in the hippocampus and the entorhinal cortex. Ann Neurol 44(6):923\u2013934","journal-title":"Ann Neurol"},{"issue":"50","key":"3261_CR41","doi-asserted-by":"publisher","first-page":"14420","DOI":"10.1073\/pnas.1604288113","volume":"113","author":"LJ Chareyron","year":"2016","unstructured":"Chareyron LJ, Amaral DG, Lavenex P (2016) Selective lesion of the hippocampus increases the differentiation of immature neurons in the monkey amygdala. Proc Natl Acad Sci U S A 113(50):14420\u201314425","journal-title":"Proc Natl Acad Sci U S A"},{"issue":"2","key":"3261_CR42","doi-asserted-by":"publisher","first-page":"113","DOI":"10.1093\/jnen\/59.2.113","volume":"59","author":"AT Yachnis","year":"2000","unstructured":"Yachnis AT, Roper SN, Love A, Fancey JT, Muir D (2000) Bcl-2 immunoreactive cells with immature neuronal phenotype exist in the nonepileptic adult human brain. J Neuropathol Exp Neurol 59(2):113\u2013119","journal-title":"J Neuropathol Exp Neurol"},{"issue":"3","key":"3261_CR43","doi-asserted-by":"publisher","first-page":"452","DOI":"10.1016\/j.neuron.2021.10.036","volume":"110","author":"D Franjic","year":"2022","unstructured":"Franjic D, Skarica M, Ma S, Arellano JI, Tebbenkamp ATN, Choi J, Xu C, Li Q et al (2022) Transcriptomic taxonomy and neurogenic trajectories of adult human, macaque, and pig hippocampal and entorhinal cells. Neuron 110(3):452-469.e414","journal-title":"Neuron"},{"key":"3261_CR44","doi-asserted-by":"publisher","first-page":"851432","DOI":"10.3389\/fnana.2022.851432","volume":"16","author":"S Coviello","year":"2022","unstructured":"Coviello S, Gramuntell Y, Klimczak P, Varea E, Blasco-Iba\u00f1ez JM, Crespo C, Gutierrez A, Nacher J (2022) Phenotype and distribution of immature neurons in the human cerebral cortex layer II. Front Neuroanat 16:851432","journal-title":"Front Neuroanat"},{"issue":"7369","key":"3261_CR45","doi-asserted-by":"publisher","first-page":"382","DOI":"10.1038\/nature10487","volume":"478","author":"N Sanai","year":"2011","unstructured":"Sanai N, Nguyen T, Ihrie RA, Mirzadeh Z, Tsai HH, Wong M, Gupta N, Berger MS et al (2011) Corridors of migrating neurons in the human brain and their decline during infancy. Nature 478(7369):382\u2013386","journal-title":"Nature"},{"key":"3261_CR46","doi-asserted-by":"crossref","unstructured":"Paredes MF, James D, Gil-Perotin S, Kim H, Cotter JA, Ng C, Sandoval K, Rowitch DH et al (2016) Extensive migration of young neurons into the infant human frontal lobe. Science 354(6308):aaf7073","DOI":"10.1126\/science.aaf7073"},{"key":"3261_CR47","doi-asserted-by":"publisher","unstructured":"Nascimento MA, Biagiotti S, Herranz-P\u00e9rez V, Bueno R, Ye JY, Abel T, Rubio-Moll JS, Garcia-Verdugo JM et al (2022) Persistent postnatal migration of interneurons into the human entorhinal cortex. bioRxiv.\u00a0https:\/\/doi.org\/10.1101\/2022.03.19.484996","DOI":"10.1101\/2022.03.19.484996"},{"issue":"2","key":"3261_CR48","doi-asserted-by":"publisher","first-page":"136","DOI":"10.1016\/S1474-4422(14)70259-5","volume":"14","author":"XX Yan","year":"2015","unstructured":"Yan XX, Ma C, Bao AM, Wang XM, Gai WP (2015) Brain banking as a cornerstone of neuroscience in China. Lancet Neurol 14(2):136","journal-title":"Lancet Neurol"},{"issue":"2","key":"3261_CR49","doi-asserted-by":"publisher","first-page":"179","DOI":"10.1007\/s12264-019-00350-3","volume":"35","author":"C Ma","year":"2019","unstructured":"Ma C, Bao AM, Yan XX, Swaab DF (2019) Progress in human brain banking in China. Neurosci Bull 35(2):179\u2013182","journal-title":"Neurosci Bull"},{"issue":"2","key":"3261_CR50","doi-asserted-by":"publisher","first-page":"270","DOI":"10.1007\/s12264-018-0306-7","volume":"35","author":"W Qiu","year":"2019","unstructured":"Qiu W, Zhang H, Bao A, Zhu K, Huang Y, Yan X, Zhang J, Zhong C et al (2019) Standardized Operational Protocol for Human Brain Banking in China. Neurosci Bull 35(2):270\u2013276","journal-title":"Neurosci Bull"},{"key":"3261_CR51","doi-asserted-by":"publisher","first-page":"45","DOI":"10.3389\/fnana.2017.00045","volume":"11","author":"X Hu","year":"2017","unstructured":"Hu X, Hu ZL, Li Z, Ruan CS, Qiu WY, Pan A, Li CQ, Cai Y et al (2017) Sortilin fragments deposit at senile plaques in human cerebrum. Front Neuroanat 11:45","journal-title":"Front Neuroanat"},{"key":"3261_CR52","doi-asserted-by":"publisher","first-page":"93","DOI":"10.3389\/fnagi.2020.00093","volume":"12","author":"T Tu","year":"2020","unstructured":"Tu T, Jiang J, Zhang QL, Wan L, Li YN, Pan A, Manavis J, Yan XX (2020) extracellular sortilin proteopathy relative to \u03b2-amyloid and tau in aged and Alzheimer\u2019s disease human brains. Front Aging Neurosci 12:93","journal-title":"Front Aging Neurosci"},{"key":"3261_CR53","doi-asserted-by":"publisher","first-page":"926904","DOI":"10.3389\/fnagi.2022.926904","volume":"14","author":"J Jiang","year":"2022","unstructured":"Jiang J, Yang C, Ai JQ, Zhang QL, Cai XL, Tu T, Wan L, Wang XS et al (2022) Intraneuronal sortilin aggregation relative to granulovacuolar degeneration, tau pathogenesis and sorfra plaque formation in human hippocampal formation. Front Aging Neurosci 14:926904","journal-title":"Front Aging Neurosci"},{"issue":"7696","key":"3261_CR54","doi-asserted-by":"publisher","first-page":"377","DOI":"10.1038\/nature25975","volume":"555","author":"SF Sorrells","year":"2018","unstructured":"Sorrells SF, Paredes MF, Cebrian-Silla A, Sandoval K, Qi D, Kelley KW, James D, Mayer S et al (2018) Human hippocampal neurogenesis drops sharply in children to undetectable levels in adults. Nature 555(7696):377\u2013381","journal-title":"Nature"},{"issue":"4","key":"3261_CR55","doi-asserted-by":"publisher","first-page":"554","DOI":"10.1038\/s41591-019-0375-9","volume":"25","author":"EP Moreno-Jim\u00e9nez","year":"2019","unstructured":"Moreno-Jim\u00e9nez EP, Flor-Garc\u00eda M, Terreros-Roncal J, R\u00e1bano A, Cafini F, Pallas-Bazarra N, \u00c1vila J, Llorens-Mart\u00edn M (2019) Adult hippocampal neurogenesis is abundant in neurologically healthy subjects and drops sharply in patients with Alzheimer\u2019s disease. Nat Med 25(4):554\u2013560","journal-title":"Nat Med"},{"issue":"2","key":"3261_CR56","doi-asserted-by":"publisher","first-page":"668","DOI":"10.1038\/s41596-019-0267-y","volume":"15","author":"M Flor-Garc\u00eda","year":"2020","unstructured":"Flor-Garc\u00eda M, Terreros-Roncal J, Moreno-Jim\u00e9nez EP, \u00c1vila J, R\u00e1bano A, Llorens-Mart\u00edn M (2020) Unraveling human adult hippocampal neurogenesis. Nat Protoc 15(2):668\u2013693","journal-title":"Nat Protoc"},{"issue":"6571","key":"3261_CR57","doi-asserted-by":"publisher","first-page":"1106","DOI":"10.1126\/science.abl5163","volume":"374","author":"J Terreros-Roncal","year":"2021","unstructured":"Terreros-Roncal J, Moreno-Jim\u00e9nez EP, Flor-Garc\u00eda M, Rodr\u00edguez-Moreno CB, Trinchero MF, Cafini F, R\u00e1bano A, Llorens-Mart\u00edn M (2021) Impact of neurodegenerative diseases on human adult hippocampal neurogenesis. Science 374(6571):1106\u20131113","journal-title":"Science"},{"issue":"6590","key":"3261_CR58","doi-asserted-by":"publisher","first-page":"eabn7083","DOI":"10.1126\/science.abn7083","volume":"376","author":"JI Arellano","year":"2022","unstructured":"Arellano JI, Duque A, Rakic P (2022) Comment on \u201cImpact of neurodegenerative diseases on human adult hippocampal neurogenesis.\u201d Science 376(6590):eabn7083","journal-title":"Science"},{"issue":"6590","key":"3261_CR59","doi-asserted-by":"publisher","first-page":"eabn8861","DOI":"10.1126\/science.abn8861","volume":"376","author":"A Alvarez-Buylla","year":"2022","unstructured":"Alvarez-Buylla A, Cebrian-Silla A, Sorrells SF, Nascimento MA, Paredes MF, Garcia-Verdugo JM, Yang Z, Huang EJ (2022) Comment on \u201cImpact of neurodegenerative diseases on human adult hippocampal neurogenesis.\u201d Science 376(6590):eabn8861","journal-title":"Science"},{"issue":"12","key":"3261_CR60","doi-asserted-by":"publisher","first-page":"2554","DOI":"10.1523\/JNEUROSCI.0676-20.2020","volume":"41","author":"SF Sorrells","year":"2021","unstructured":"Sorrells SF, Paredes MF, Zhang Z, Kang G, Pastor-Alonso O, Biagiotti S, Page CE, Sandoval K et al (2021) Positive controls in adults and children support that very few, if any, new neurons are born in the adult human hippocampus. J Neurosci 41(12):2554\u20132565","journal-title":"J Neurosci"},{"issue":"10","key":"3261_CR61","doi-asserted-by":"publisher","first-page":"2229","DOI":"10.1093\/cercor\/bhm255","volume":"18","author":"MA G\u00f3mez-Climent","year":"2008","unstructured":"G\u00f3mez-Climent MA, Castillo-G\u00f3mez E, Varea E, Guirado R, Blasco-Ib\u00e1\u00f1ez JM, Crespo C, Mart\u00ednez-Guijarro FJ, N\u00e1cher J (2008) A population of prenatally generated cells in the rat paleocortex maintains an immature neuronal phenotype into adulthood. Cereb Cortex 18(10):2229\u20132240","journal-title":"Cereb Cortex"},{"issue":"1","key":"3261_CR62","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1002\/cne.10874","volume":"467","author":"JP Brown","year":"2003","unstructured":"Brown JP, Couillard-Despr\u00e9s S, Cooper-Kuhn CM, Winkler J, Aigner L, Kuhn HG (2003) Transient expression of doublecortin during adult neurogenesis. J Comp Neurol 467(1):1\u201310","journal-title":"J Comp Neurol"},{"key":"3261_CR63","doi-asserted-by":"publisher","first-page":"929469","DOI":"10.3389\/fnins.2022.929469","volume":"16","author":"A Llorca","year":"2022","unstructured":"Llorca A, Deogracias R (2022) Origin, development, and synaptogenesis of cortical interneurons. Front Neurosci 16:929469","journal-title":"Front Neurosci"},{"issue":"17","key":"3261_CR64","doi-asserted-by":"publisher","first-page":"2843","DOI":"10.1002\/cne.24711","volume":"527","author":"JK Ellis","year":"2019","unstructured":"Ellis JK, Sorrells SF, Mikhailova S, Chavali M, Chang S, Sabeur K, McQuillen P, Rowitch DH (2019) Ferret brain possesses young interneuron collections equivalent to human postnatal migratory streams. J Comp Neurol 527(17):2843\u20132859","journal-title":"J Comp Neurol"},{"issue":"9","key":"3261_CR65","doi-asserted-by":"publisher","first-page":"2097","DOI":"10.1016\/j.stemcr.2022.07.015","volume":"17","author":"DDL Porter","year":"2022","unstructured":"Porter DDL, Henry SN, Ahmed S, Rizzo AL, Makhlouf R, Gregg C, Morton PD (2022) Neuroblast migration along cellular substrates in the developing porcine brain. Stem Cell Reports 17(9):2097\u20132110","journal-title":"Stem Cell Reports"},{"key":"3261_CR66","doi-asserted-by":"publisher","first-page":"101133","DOI":"10.1016\/j.dcn.2022.101133","volume":"56","author":"CE Page","year":"2022","unstructured":"Page CE, Biagiotti SW, Alderman PJ, Sorrells SF (2022) Immature excitatory neurons in the amygdala come of age during puberty. Dev Cogn Neurosci 56:101133","journal-title":"Dev Cogn Neurosci"},{"issue":"5","key":"3261_CR67","doi-asserted-by":"publisher","first-page":"e1137","DOI":"10.1038\/tp.2017.104","volume":"7","author":"LA Ajram","year":"2017","unstructured":"Ajram LA, Horder J, Mendez MA, Galanopoulos A, Brennan LP, Wichers RH, Robertson DM, Murphy CM et al (2017) Shifting brain inhibitory balance and connectivity of the prefrontal cortex of adults with autism spectrum disorder. Transl Psychiatry 7(5):e1137","journal-title":"Transl Psychiatry"},{"key":"3261_CR68","doi-asserted-by":"publisher","first-page":"263310552095697","DOI":"10.1177\/2633105520956973","volume":"15","author":"P Mosili","year":"2020","unstructured":"Mosili P, Maikoo S, Mabandla MV, Qulu L (2020) The pathogenesis of fever-induced febrile seizures and its current state. Neurosci Insights 15:2633105520956973","journal-title":"Neurosci Insights"},{"key":"3261_CR69","doi-asserted-by":"crossref","unstructured":"D\u00f3ra F, Renner \u00c9, Keller D, Palkovits M, Dobolyi \u00c1 (2022) Transcriptome profiling of the dorsomedial prefrontal cortex in suicide victims. Int J Mol Sci 23(13):7067","DOI":"10.3390\/ijms23137067"},{"issue":"6","key":"3261_CR70","doi-asserted-by":"publisher","first-page":"501","DOI":"10.1016\/j.biopsych.2022.06.017","volume":"92","author":"OD Howes","year":"2022","unstructured":"Howes OD, Shatalina E (2022) Integrating the neurodevelopmental and dopamine hypotheses of schizophrenia and the role of cortical excitation-inhibition balance. Biol Psychiatry 92(6):501\u2013513","journal-title":"Biol Psychiatry"},{"key":"3261_CR71","doi-asserted-by":"publisher","first-page":"106937","DOI":"10.1016\/j.eplepsyres.2022.106937","volume":"183","author":"WE Lado","year":"2022","unstructured":"Lado WE, Xu X, Hablitz JJ (2022) Modulation of epileptiform activity by three subgroups of GABAergic interneurons in mouse somatosensory cortex. Epilepsy Res 183:106937","journal-title":"Epilepsy Res"},{"issue":"2","key":"3261_CR72","doi-asserted-by":"publisher","first-page":"110232","DOI":"10.1016\/j.celrep.2021.110232","volume":"38","author":"HK Yao","year":"2022","unstructured":"Yao HK, Guet-McCreight A, Mazza F, Moradi Chameh H, Prevot TD, Griffiths JD, Tripathy SJ, Valiante TA et al (2022) Reduced inhibition in depression impairs stimulus processing in human cortical microcircuits. Cell Rep 38(2):110232","journal-title":"Cell Rep"}],"container-title":["Molecular Neurobiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12035-023-03261-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s12035-023-03261-7\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12035-023-03261-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,4,22]],"date-time":"2023-04-22T05:14:49Z","timestamp":1682140489000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s12035-023-03261-7"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,3,6]]},"references-count":72,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2023,6]]}},"alternative-id":["3261"],"URL":"https:\/\/doi.org\/10.1007\/s12035-023-03261-7","relation":{"has-preprint":[{"id-type":"doi","id":"10.21203\/rs.3.rs-2168886\/v1","asserted-by":"object"}]},"ISSN":["0893-7648","1559-1182"],"issn-type":[{"value":"0893-7648","type":"print"},{"value":"1559-1182","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,3,6]]},"assertion":[{"value":"17 October 2022","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"4 February 2023","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"6 March 2023","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The use of postmodern human brains was approved by the Ethics Committee for Research and Education at Xiangya School of Medicine, in compliance with the Code of Ethics of the World Medical Association (Declaration of Helsinki). Written informed consent for body\/brain donation was obtained by the willed body donation center of Xiangya School of Medicine.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics Approval and Consent to Participate"}},{"value":"Not applicable.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for Publication"}},{"value":"The authors declare no competing interests.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}]}}