{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,21]],"date-time":"2026-05-21T13:06:17Z","timestamp":1779368777603,"version":"3.53.0"},"reference-count":50,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2024,6,13]],"date-time":"2024-06-13T00:00:00Z","timestamp":1718236800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2024,6,13]],"date-time":"2024-06-13T00:00:00Z","timestamp":1718236800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Mol Neurobiol"],"published-print":{"date-parts":[[2025,1]]},"DOI":"10.1007\/s12035-024-04294-2","type":"journal-article","created":{"date-parts":[[2024,6,13]],"date-time":"2024-06-13T02:01:22Z","timestamp":1718244082000},"page":"461-474","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Attenuation of Nerve Agent Induced Neurodegenerative and Neuroinflammatory Changes in Rats with New Combination Treatment of Galantamine, Atropine and Midazolam"],"prefix":"10.1007","volume":"62","author":[{"given":"Naveen","family":"Singh","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"RamaRao","family":"Golime","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abdhesh","family":"Kumar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tuhin","family":"Roy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,6,13]]},"reference":[{"key":"4294_CR1","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1016\/j.tox.2019.05.007","volume":"423","author":"R Golime","year":"2019","unstructured":"Golime R, Singh N, Palit M (2019) Epigenetic and autophagic changes after nerve agent exposure in the rat piriform cortex and hippocampus. Toxicology 423:54\u201361","journal-title":"Toxicology"},{"issue":"6","key":"4294_CR2","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1002\/(SICI)1099-1263(199811\/12)18:6<393::AID-JAT528>3.0.CO;2-0","volume":"18","author":"MA Brown","year":"1998","unstructured":"Brown MA, Brix KA (1998) Review of health consequences from high-, intermediate- and low-level exposure to organophosphorus nerve agents. J Appl Toxicol 18(6):393\u2013408","journal-title":"J Appl Toxicol"},{"issue":"6","key":"4294_CR3","doi-asserted-by":"crossref","first-page":"1476","DOI":"10.1016\/j.neuro.2012.09.001","volume":"33","author":"M Furtado De Araujo","year":"2012","unstructured":"Furtado De Araujo M, Rossetti F, Chanda S, Yourick D (2012) Exposure to nerve agents: from status epilepticus to neuroinflammation, brain damage, neurogenesis and epilepsy. Neurotoxicology 33(6):1476\u20131490","journal-title":"Neurotoxicology"},{"key":"4294_CR4","doi-asserted-by":"crossref","unstructured":"Golime RR, Singh N (2023) Molecular interactions of chemical warfare agents with biological systems. In: Das S, Thomas S, Das PP (eds) Sensing of Deadly Toxic Chemical Warfare Agents, Nerve Agent Simulants, and their Toxicological Aspects. Elsevier Netherlands, pp 687\u2013710","DOI":"10.1016\/B978-0-323-90553-4.00028-7"},{"key":"4294_CR5","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1002\/(SICI)1099-1263(199707)17:4<255::AID-JAT441>3.0.CO;2-D","volume":"17","author":"TM Shih","year":"1997","unstructured":"Shih TM, McDonough JH (1997) Neurochemical mechanisms in soman-induced seizures. J Appl Toxicol 17:255\u2013264","journal-title":"J Appl Toxicol"},{"key":"4294_CR6","doi-asserted-by":"crossref","first-page":"528","DOI":"10.1016\/S0022-3565(24)29259-4","volume":"299","author":"EG Duysen","year":"2001","unstructured":"Duysen EG, Li B, Xie W, Schopfer LM, Anderson RS, Broomfield CA, Lockridge O (2001) Evidence for non-acetylcholinesterase targets of organophosphorus nerve agent: super sensitivity of acetylcholinesterase knockout mouse to VX lethality. J Pharmacol Exp Ther 299:528\u2013535","journal-title":"J Pharmacol Exp Ther"},{"issue":"17","key":"4294_CR7","doi-asserted-by":"crossref","first-page":"2638","DOI":"10.1021\/acschemneuro.0c00311","volume":"11","author":"N Singh","year":"2020","unstructured":"Singh N, Golime R, Acharya J, Palit M (2020) Quantitative proteomic changes after organophosphorous nerve agent exposure in the rat hippocampus. ACS Chem Neurosci 11(17):2638\u20132648","journal-title":"ACS Chem Neurosci"},{"key":"4294_CR8","doi-asserted-by":"crossref","first-page":"905","DOI":"10.1007\/s12264-021-00662-3","volume":"37","author":"S Wang","year":"2021","unstructured":"Wang S, He H, Long J, Sui X, Yang J, Lin G, Luo Y (2021) TRPV4 regulates soman-induced status epilepticus and secondary brain injury via NMDA receptor and NLRP3 inflammasome. Neuroscience bulletin 37:905\u2013920","journal-title":"Neuroscience bulletin"},{"key":"4294_CR9","doi-asserted-by":"crossref","first-page":"482","DOI":"10.1002\/(SICI)1096-9861(19970224)378:4<482::AID-CNE4>3.0.CO;2-Z","volume":"378","author":"LA Zimmer","year":"1997","unstructured":"Zimmer LA, Ennis M, Shipley MT (1997) Soman-induced seizures rapidly activate astrocytes and microglia in discrete brain regions. J Comp Neurol 378:482\u2013492","journal-title":"J Comp Neurol"},{"key":"4294_CR10","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1016\/j.cortex.2015.10.003","volume":"74","author":"F Sanchez-Santed","year":"2016","unstructured":"Sanchez-Santed F, Colomina MT, Hernandez EH (2016) Organophosphate pesticide exposure and neurodegeneration. Cortex 74:417\u201326","journal-title":"Cortex"},{"key":"4294_CR11","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.mam.2014.05.001","volume":"40","author":"R Kang","year":"2014","unstructured":"Kang R, Chen R, Zhang Q, Hou W, Wu S, Cao L, Tang D (2014) HMGB1 in health and disease. Mol Aspects Med 40:1\u2013116","journal-title":"Mol Aspects Med"},{"issue":"12","key":"4294_CR12","doi-asserted-by":"crossref","first-page":"633","DOI":"10.1016\/j.it.2012.10.005","volume":"33","author":"H Yanai","year":"2012","unstructured":"Yanai H, Ban T, Taniguchi T (2012) High-mobility group box family of proteins: ligand and sensor for innate immunity. Trends Immunol 33(12):633\u2013640","journal-title":"Trends Immunol"},{"issue":"6","key":"4294_CR13","doi-asserted-by":"crossref","first-page":"607","DOI":"10.7205\/MILMED.172.6.607","volume":"172","author":"A Hoffman","year":"2007","unstructured":"Hoffman A, Eisenkraft A, Finkelstein A, Schein O, Rotman E (2007) A decade after the Tokyo sarin attack: a review of neurological follow-up of the victims. Mil Med 172(6):607\u2013610","journal-title":"Mil Med"},{"issue":"1","key":"4294_CR14","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/1471-2202-15-47","volume":"15","author":"G RamaRao","year":"2014","unstructured":"RamaRao G, Afley P, Acharya J, Bhattacharya BK (2014) Efficacy of antidotes (midazolam, atropine and HI-6) on nerve agent induced molecular and neuropathological changes. BMC Neurosci 15(1):1\u201311","journal-title":"BMC Neurosci"},{"key":"4294_CR15","doi-asserted-by":"crossref","first-page":"523","DOI":"10.1016\/S0378-4274(98)00259-8","volume":"102\u2013103","author":"TL Kurt","year":"1998","unstructured":"Kurt TL (1998) Epidemiological association in US veterans between Gulf war illness and exposures to anticholinesterases. Toxicol Lett 102\u2013103:523\u2013526","journal-title":"Toxicol Lett"},{"key":"4294_CR16","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1002\/j.1552-4604.1998.tb04420.x","volume":"38","author":"MT Marino","year":"1998","unstructured":"Marino MT, Schuster BG, Brueckner RP, Lin E, Kaminskis A, Lasseter KC (1998) Population pharmacokinetics and pharmacodynamics of pyridostigmine bromide for prophylaxis against nerve agents in humans. J Clin Pharmacol 38:227\u2013235","journal-title":"J Clin Pharmacol"},{"key":"4294_CR17","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1016\/S0065-2423(04)38006-6","volume":"38","author":"J Bajgar","year":"2004","unstructured":"Bajgar J (2004) Organophosphate\/nerve agent poisoning: mechanism of action, diagnosis, prophylaxis, and treatment. Adv Clin Chem 38:151\u2013216","journal-title":"Adv Clin Chem"},{"issue":"2","key":"4294_CR18","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1016\/S0272-0590(81)80058-9","volume":"1","author":"JG Clement","year":"1981","unstructured":"Clement JG (1981) Toxicology and pharmacology of bispyridinium oximes insight into the mechanism of action vs soman poisoning in vivo. Fundam Appl Toxicol 1(2):193\u2013202","journal-title":"Fundam Appl Toxicol"},{"issue":"7","key":"4294_CR19","doi-asserted-by":"crossref","first-page":"1283","DOI":"10.1016\/0006-2952(82)90017-X","volume":"31","author":"JG Clement","year":"1982","unstructured":"Clement JG (1982) HI-6: reactivation of central and peripheral acetylcholinesterase following inhibition by soman, sarin and tabun in vivo in the rat. Biochem Pharmacol 31(7):1283\u20131287","journal-title":"Biochem Pharmacol"},{"key":"4294_CR20","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1002\/jat.2550140502","volume":"14","author":"RM Dawson","year":"1994","unstructured":"Dawson RM (1994) Review of oximes available for treatment of nerve agent poisoning. J Appl Toxicol 14:317\u2013331","journal-title":"J Appl Toxicol"},{"issue":"4","key":"4294_CR21","doi-asserted-by":"crossref","first-page":"738","DOI":"10.1007\/s12640-017-9815-9","volume":"33","author":"R Golime","year":"2018","unstructured":"Golime R, Palit M, Acharya J, Dubey DK (2018) Neuroprotective effects of galantamine on nerve agent-induced neuroglial and biochemical changes. Neurotox Res 33(4):738\u2013748","journal-title":"Neurotox Res"},{"key":"4294_CR22","doi-asserted-by":"crossref","first-page":"13220","DOI":"10.1073\/pnas.0605370103","volume":"103","author":"EX Albuquerque","year":"2006","unstructured":"Albuquerque EX, Pereira EF, Aracava Y, Fawcett WP, Oliveira M, Randall WR, Hamilton TA, Kan RK, Romano JA Jr, Adler M (2006) Effective countermeasure against poisoning by organophosphorus insecticides and nerve agents. Proc Natl Acad Sci USA 103:13220\u201313225","journal-title":"Proc Natl Acad Sci USA"},{"issue":"1\u20133","key":"4294_CR23","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1016\/S0014-2999(00)00093-5","volume":"393","author":"A Maelicke","year":"2000","unstructured":"Maelicke A, Albuquerque EX (2000) Allosteric modulation of nicotinic acetylcholine receptors as a treatment strategy for Alzheimer\u2019s disease. Eur J Pharmacol 393(1\u20133):165\u2013170","journal-title":"Eur J Pharmacol"},{"issue":"4","key":"4294_CR24","doi-asserted-by":"crossref","first-page":"479","DOI":"10.1002\/neu.10146","volume":"53","author":"EF Pereira","year":"2002","unstructured":"Pereira EF, Hilmas C, Santos MD, Alkondon M, Maelicke A, Albuquerque EX (2002) Unconventional ligands and modulators of nicotinic receptors. J Neurobiol 53(4):479\u2013500","journal-title":"J Neurobiol"},{"issue":"1","key":"4294_CR25","doi-asserted-by":"crossref","first-page":"32","DOI":"10.14712\/fb2013059010032","volume":"59","author":"MM Saghafi","year":"2013","unstructured":"Saghafi MM, Zivin M, Pregelj P (2013) Galantamine as a preventive of diisopropylphosphorofluoridate toxicity effects in rat brain. Folia Biol 59(1):32","journal-title":"Folia Biol"},{"issue":"3","key":"4294_CR26","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1016\/j.toxlet.2011.03.020","volume":"203","author":"G RamaRao","year":"2011","unstructured":"RamaRao G, Acharya JN, Bhattacharya BK (2011) Changes of protein oxidation, calpain and cytoskeletal proteins (alpha tubulin and pNF-H) levels in rat brain after nerve agent poisoning. Toxicol Lett 203(3):227\u2013236","journal-title":"Toxicol Lett"},{"key":"4294_CR27","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1007\/s002040050670","volume":"74","author":"TM Shih","year":"2000","unstructured":"Shih TM, McDonough JH (2000) Efficacy of biperiden and atropine as anticonvulsant treatment for organophosphorus nerve agent intoxication. Arch Toxicol 74:165\u2013172","journal-title":"Arch Toxicol"},{"key":"4294_CR28","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1016\/0006-2952(61)90145-9","volume":"7","author":"GL Ellman","year":"1961","unstructured":"Ellman GL, Courtney KD, Andres V Jr, Feather-stone RM (1961) A new and rapid colorimetric determination of acetylcholinesterase activity. Biochem Pharmacol 7:88\u201395","journal-title":"Biochem Pharmacol"},{"key":"4294_CR29","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1016\/0003-2697(76)90527-3","volume":"72","author":"MM Bradford","year":"1976","unstructured":"Bradford MM (1976) A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 72:248\u2013254","journal-title":"Anal Biochem"},{"key":"4294_CR30","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1016\/j.neuro.2004.07.011","volume":"26","author":"T Myhrer","year":"2005","unstructured":"Myhrer T, Andersen JM, Nguyen NH, Aas P (2005) Soman-induced convulsions in rats terminated with pharmacological agents after 45 min: neuropathology and cognitive performance. Neurotoxicol 26:39\u201348","journal-title":"Neurotoxicol"},{"key":"4294_CR31","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1016\/S0006-8993(96)01387-X","volume":"751","author":"LC Schmued","year":"1997","unstructured":"Schmued LC, Albertson C, Slikker W (1997) Fluoro-Jade: a novel fluorochrome for the sensitive and reliable histochemical localization of neuronal degeneration. Brain Res 751:37\u201346","journal-title":"Brain Res"},{"key":"4294_CR32","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1016\/0091-3057(92)90076-R","volume":"41","author":"CA Castro","year":"1991","unstructured":"Castro CA, Larsen T, Finger AV, Solana RP, McMaster SB (1991) Behavioral efficacy of diazepam against nerve agent exposure in rhesus monkey. Pharmacol Biochem Behav 41:159\u2013164","journal-title":"Pharmacol Biochem Behav"},{"key":"4294_CR33","doi-asserted-by":"crossref","first-page":"208","DOI":"10.1017\/S1049023X00001072","volume":"18","author":"P Aas","year":"2003","unstructured":"Aas P (2003) Future considerations for the medical management of nerve agent intoxication. Prehospital Disaster Med 18:208\u2013216","journal-title":"Prehospital Disaster Med"},{"issue":"2","key":"4294_CR34","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1016\/S0149-7634(05)80151-4","volume":"17","author":"JH McDonough Jr","year":"1993","unstructured":"McDonough JH Jr, Shih TM (1993) Pharmacological modulation of soman-induced seizures. Neurosci Biobehav Rev 17(2):203\u2013215","journal-title":"Neurosci Biobehav Rev"},{"issue":"5","key":"4294_CR35","doi-asserted-by":"crossref","first-page":"559","DOI":"10.1016\/S0149-7634(96)00050-4","volume":"21","author":"JRJH McDonough","year":"1997","unstructured":"McDonough JRJH, Shih TM (1997) Neuropharmacological mechanisms of nerve agent-induced seizure and neuropathology. Neurosci Biobehav Rev 21(5):559\u2013579","journal-title":"Neurosci Biobehav Rev"},{"issue":"6","key":"4294_CR36","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1016\/S0165-6147(97)89540-5","volume":"18","author":"Y Solberg","year":"1997","unstructured":"Solberg Y, Belkin M (1997) The role of excitotoxicity in organophosphorous nerve agents central poisoning. Trends Pharmacol Sci 18(6):183\u2013185","journal-title":"Trends Pharmacol Sci"},{"issue":"1","key":"4294_CR37","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/1742-2094-8-1","volume":"8","author":"KD Spradling","year":"2011","unstructured":"Spradling KD, Lumley LA, Robison CL, Meyerhoff JL, Dillman JF (2011) Transcriptional responses of the nerve agent-sensitive brain regions amygdala, hippocampus, piriform cortex, septum, and thalamus following exposure to the organophosphonate anticholinesterase sarin. J Neuroinflammation 8(1):1\u201321","journal-title":"J Neuroinflammation"},{"issue":"139\u2013162","key":"4294_CR38","first-page":"3","volume":"29","author":"U Andersson","year":"2011","unstructured":"Andersson U, Tracey KJ (2011) HMGB1 is a therapeutic target for sterile inflammation and infection. Annu Rev Immunol 29(139\u2013162):3","journal-title":"Annu Rev Immunol"},{"key":"4294_CR39","doi-asserted-by":"publisher","first-page":"130417","DOI":"10.1016\/j.chemosphere.2021","volume":"278","author":"GCC Weis","year":"2021","unstructured":"Weis GCC, Assmann CE, Mostardeiro VB, Alves AO, da Rosa JR, Pillat MM, de Andrade CM, Schetinger MRC et al (2021) Chlorpyrifos pesticide promotes oxidative stress and increases inflammatory states in BV-2 microglial cells: a role in neuroinflammation. Chemosphere 278:130417. https:\/\/doi.org\/10.1016\/j.chemosphere.2021","journal-title":"Chemosphere"},{"issue":"3","key":"4294_CR40","doi-asserted-by":"publisher","first-page":"167","DOI":"10.1007\/s00204-002-0425-8","volume":"77","author":"E Gilat","year":"2003","unstructured":"Gilat E, Goldman M, Lahat E, Levy A, Rabinovitz I, Cohen G, Brandeis R, Amitai G et al (2003) Nasal midazolam as a novel anticonvulsive treatment against organophosphate-induced seizure activity in the guinea pig. Arch Toxicol 77(3):167\u2013172. https:\/\/doi.org\/10.1007\/s00204-002-0425-8","journal-title":"Arch Toxicol"},{"issue":"2","key":"4294_CR41","first-page":"90","volume":"3","author":"C Liu","year":"2012","unstructured":"Liu C, Li Y, Lein PJ, Ford BD (2012) Spatiotemporal patterns of GFAP upregulation in rat brain following acute intoxication with diisopropylfluorophosphate (DFP). Curr Neurobiol 3(2):90","journal-title":"Curr Neurobiol"},{"issue":"3","key":"4294_CR42","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1517\/14740338.4.3.433","volume":"4","author":"JP O\u2019Callaghan","year":"2005","unstructured":"O\u2019Callaghan JP, Sriram K (2005) Glial fibrillary acidic protein and related glial proteins as biomarkers of neurotoxicity. Expert Opin Drug Saf 4(3):433\u2013442","journal-title":"Expert Opin Drug Saf"},{"key":"4294_CR43","doi-asserted-by":"publisher","DOI":"10.1016\/j.nbd.2019.03.031","volume":"133","author":"M Putra","year":"2020","unstructured":"Putra M, Sharma S, Gage M, Gasser G, Hinojo-Perez A, Olson A, Gregory-Flores A, Puttachary S et al (2020) Inducible nitric oxide synthase inhibitor, 1400W, mitigates DFP-induced long-term neurotoxicity in the rat model. Neurobiol Dis 133:104443. https:\/\/doi.org\/10.1016\/j.nbd.2019.03.031","journal-title":"Neurobiol Dis"},{"issue":"3","key":"4294_CR44","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1016\/S0161-813X(01)00022-5","volume":"22","author":"I Svensson","year":"2001","unstructured":"Svensson I, Waara L, Johansson L, Bucht A, Cassel G (2001) Soman-induced interleukin-1\u03b2 mRNA and protein in rat brain. Neurotoxicology 22(3):355\u2013362","journal-title":"Neurotoxicology"},{"issue":"3","key":"4294_CR45","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1016\/S0304-3940(03)00818-8","volume":"349","author":"AJ Williams","year":"2003","unstructured":"Williams AJ, Berti R, Yao C, Price RA, Velarde LC, Koplovitz I, Dave JR (2003) Central neuro-inflammatory gene response following soman exposure in the rat. Neurosci Lett 349(3):147\u2013150","journal-title":"Neurosci Lett"},{"key":"4294_CR46","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1016\/S0091-3057(96)00292-4","volume":"56","author":"G Lallement","year":"1997","unstructured":"Lallement G, Clarencon D, Brouchier G, Baubichon D, Galonnier M, Blanchet G, Mestries J-C (1997) Efficacy of atropine\/pralidoxime\/diazepam or atropine\/HI-6\/prodiazepam in primates intoxicated by soman. Pharmacol Biochem Behav 56:325\u2013332","journal-title":"Pharmacol Biochem Behav"},{"issue":"4","key":"4294_CR47","doi-asserted-by":"crossref","first-page":"711","DOI":"10.1016\/0091-3057(92)90019-C","volume":"42","author":"IH Philippens","year":"1992","unstructured":"Philippens IH, Melchers BP, De Groot DM, Wolthuis OL (1992) Behavioral performance, brain histology, and EEG sequela after immediate combined atropine\/diazepam treatment of soman-intoxicated rats. Pharmacol Biochem Behav 42(4):711\u2013719","journal-title":"Pharmacol Biochem Behav"},{"issue":"2","key":"4294_CR48","doi-asserted-by":"publisher","first-page":"69","DOI":"10.1016\/s0041-008x(03)00019-x","volume":"188","author":"TM Shih","year":"2003","unstructured":"Shih TM, Duniho SM, McDonough JH (2003) Control of nerve agent-induced seizures is critical for neuroprotection and survival. Toxicol Appl Pharmacol 188(2):69\u201380. https:\/\/doi.org\/10.1016\/s0041-008x(03)00019-x","journal-title":"Toxicol Appl Pharmacol"},{"key":"4294_CR49","doi-asserted-by":"publisher","first-page":"132","DOI":"10.1016\/j.neuro.2015.05.001","volume":"49","author":"S Chapman","year":"2015","unstructured":"Chapman S, Yaakov G, Egoz I, Rabinovitz I, Raveh L, Kadar T, Gilat E, Grauer E (2015) Sarin-induced brain damage in rats is attenuated by delayed administration of midazolam. Neurotoxicology 49:132\u20138. https:\/\/doi.org\/10.1016\/j.neuro.2015.05.001","journal-title":"Neurotoxicology"},{"issue":"8","key":"4294_CR50","doi-asserted-by":"publisher","first-page":"409","DOI":"10.3390\/toxics10080409","volume":"10","author":"TH Figueiredo","year":"2022","unstructured":"Figueiredo TH, Aroniadou-Anderjaska V, Pidoplichko VI, Apland JP, Braga MFM (2022) Antiseizure and neuroprotective efficacy of midazolam in comparison with tezampanel (LY293558) against soman-induced status epilepticus. Toxics 10(8):409. https:\/\/doi.org\/10.3390\/toxics10080409","journal-title":"Toxics"}],"container-title":["Molecular Neurobiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12035-024-04294-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s12035-024-04294-2\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12035-024-04294-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,1,8]],"date-time":"2025-01-08T11:13:15Z","timestamp":1736334795000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s12035-024-04294-2"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,6,13]]},"references-count":50,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2025,1]]}},"alternative-id":["4294"],"URL":"https:\/\/doi.org\/10.1007\/s12035-024-04294-2","relation":{},"ISSN":["0893-7648","1559-1182"],"issn-type":[{"value":"0893-7648","type":"print"},{"value":"1559-1182","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,6,13]]},"assertion":[{"value":"15 January 2024","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"7 June 2024","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"13 June 2024","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare no competing interests.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}},{"value":"Animals used in this study were treated as per all animal protocols were approved by the Institutional Animals Ethics Committee (No.37\/1999\/CPCSEA) in accordance with the PCA Acts of 1960 and 1998. The care and maintenance of animals were in accordance the Committee for the Purpose of Control of Experimental Animals (CPCSEA, India) guidelines, which are in line with the international criteria of the National Research Council\u2019s Guide for the Care and Use of Laboratory Animals.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics Approval"}},{"value":"All authors gave consent to the manuscript for submission\/publication.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for Publication"}}]}}