{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,30]],"date-time":"2026-05-30T01:29:46Z","timestamp":1780104586569,"version":"3.54.0"},"reference-count":198,"publisher":"Springer Science and Business Media LLC","issue":"11","license":[{"start":{"date-parts":[[2025,5,26]],"date-time":"2025-05-26T00:00:00Z","timestamp":1748217600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2025,5,26]],"date-time":"2025-05-26T00:00:00Z","timestamp":1748217600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"funder":[{"name":"Basic Research Project of Shenzhen Science and Technology Innovation Commission","award":["JCYJ20220530144801003"],"award-info":[{"award-number":["JCYJ20220530144801003"]}]},{"name":"Basic Research Project of Shenzhen Science and Technology Innovation Commission","award":["JCYJ20220530144801003"],"award-info":[{"award-number":["JCYJ20220530144801003"]}]},{"name":"Basic Research Project of Shenzhen Science and Technology Innovation Commission","award":["JCYJ20220530144801003"],"award-info":[{"award-number":["JCYJ20220530144801003"]}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82071362"],"award-info":[{"award-number":["82071362"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82071362"],"award-info":[{"award-number":["82071362"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82071362"],"award-info":[{"award-number":["82071362"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Mol Neurobiol"],"published-print":{"date-parts":[[2025,11]]},"DOI":"10.1007\/s12035-025-05055-5","type":"journal-article","created":{"date-parts":[[2025,5,26]],"date-time":"2025-05-26T17:51:50Z","timestamp":1748281910000},"page":"14947-14965","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Calcium Signaling in Astrocytes and Its Role in the\u00a0Central Nervous System Injury"],"prefix":"10.1007","volume":"62","author":[{"ORCID":"https:\/\/orcid.org\/0009-0005-9543-9888","authenticated-orcid":false,"given":"Xinyue","family":"Li","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lu","family":"Ding","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hong","family":"Nie","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David Y. B.","family":"Deng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2025,5,26]]},"reference":[{"issue":"7668","key":"5055_CR1","doi-asserted-by":"publisher","first-page":"396","DOI":"10.1038\/548396a","volume":"548","author":"LE Clarke","year":"2017","unstructured":"Clarke LE, Liddelow SA (2017) Diversity reaches the stars. Nature 548(7668):396\u2013397. https:\/\/doi.org\/10.1038\/548396a","journal-title":"Nature"},{"issue":"7","key":"5055_CR2","doi-asserted-by":"publisher","first-page":"R326","DOI":"10.1016\/j.cub.2021.01.056","volume":"31","author":"P Hasel","year":"2021","unstructured":"Hasel P, Liddelow SA (2021) Astrocytes. Curr Biol 31(7):R326\u2013R327. https:\/\/doi.org\/10.1016\/j.cub.2021.01.056","journal-title":"Curr Biol"},{"issue":"9","key":"5055_CR3","doi-asserted-by":"publisher","first-page":"758","DOI":"10.1016\/j.it.2020.07.004","volume":"41","author":"MV Sofroniew","year":"2020","unstructured":"Sofroniew MV (2020) Astrocyte reactivity: subtypes, states, and functions in CNS innate immunity. Trends Immunol 41(9):758\u2013770. https:\/\/doi.org\/10.1016\/j.it.2020.07.004","journal-title":"Trends Immunol"},{"key":"5055_CR4","doi-asserted-by":"publisher","first-page":"101","DOI":"10.1146\/annurev-neuro-091922-031205","volume":"46","author":"B D\u00edaz-Castro","year":"2023","unstructured":"D\u00edaz-Castro B, Robel S, Mishra A (2023) Astrocyte endfeet in brain function and pathology: open questions. Ann Rev Neurosci 46:101\u2013121. https:\/\/doi.org\/10.1146\/annurev-neuro-091922-031205","journal-title":"Ann Rev Neurosci"},{"issue":"3","key":"5055_CR5","doi-asserted-by":"publisher","first-page":"239","DOI":"10.15252\/embj.201592705","volume":"35","author":"A Verkhratsky","year":"2016","unstructured":"Verkhratsky A, Matteoli M, Parpura V, Mothet J, Zorec R (2016) Astrocytes as secretory cells of the central nervous system: idiosyncrasies of vesicular secretion. EMBO J 35(3):239\u2013257. https:\/\/doi.org\/10.15252\/embj.201592705","journal-title":"EMBO J"},{"issue":"4","key":"5055_CR6","doi-asserted-by":"publisher","first-page":"576","DOI":"10.1016\/j.neuron.2020.12.008","volume":"109","author":"J Nagai","year":"2021","unstructured":"Nagai J et al (2021) Behaviorally consequential astrocytic regulation of neural circuits. Neuron 109(4):576\u2013596. https:\/\/doi.org\/10.1016\/j.neuron.2020.12.008","journal-title":"Neuron"},{"key":"5055_CR7","doi-asserted-by":"publisher","unstructured":"Lim D, Semyanov A, Genazzani A, Verkhratsky A (2021) Chapter One - Calcium signaling in neuroglia. In: Marchi S, Galluzzi L (eds)\u00a0International Review of Cell and Molecular Biology, in Inter-Organellar Ca2+ Signaling in Health and Disease - Part A, Academic Press, vol 362, pp 1\u201353. https:\/\/doi.org\/10.1016\/bs.ircmb.2021.01.003","DOI":"10.1016\/bs.ircmb.2021.01.003"},{"issue":"6565","key":"5055_CR8","doi-asserted-by":"publisher","first-page":"eabh2858","DOI":"10.1126\/science.abh2858","volume":"374","author":"J Lezmy","year":"2021","unstructured":"Lezmy J, Arancibia-Carcamo L, Quintela-Lopez T, Sherman DL, Brophy PJ, Attwell D (2021) Astrocyte Ca2+-evoked ATP release regulates myelinated axon excitability and conduction speed. Science 374(6565):eabh2858. https:\/\/doi.org\/10.1126\/science.abh2858","journal-title":"Science"},{"issue":"1","key":"5055_CR9","doi-asserted-by":"publisher","first-page":"3","DOI":"10.1042\/EBC20220077","volume":"67","author":"I Fern\u00e1ndez-Gonz\u00e1lez","year":"2023","unstructured":"Fern\u00e1ndez-Gonz\u00e1lez I, Galea E (2023) Astrocyte strategies in the energy-efficient brain. Essays Biochem 67(1):3\u201316. https:\/\/doi.org\/10.1042\/EBC20220077","journal-title":"Essays Biochem"},{"issue":"10","key":"5055_CR10","doi-asserted-by":"publisher","first-page":"1532","DOI":"10.1016\/j.cmet.2022.09.002","volume":"34","author":"D Herrera Moro Chao","year":"2022","unstructured":"Herrera Moro Chao D et al (2022) Hypothalamic astrocytes control systemic glucose metabolism and energy balance\u201d. Cell Metabolism 34(10):1532\u201315476. https:\/\/doi.org\/10.1016\/j.cmet.2022.09.002","journal-title":"Cell Metabolism"},{"issue":"8","key":"5055_CR11","doi-asserted-by":"publisher","first-page":"e1006795","DOI":"10.1371\/journal.pcbi.1006795","volume":"15","author":"A Denizot","year":"2019","unstructured":"Denizot A, Arizono M, N\u00e4gerl UV, Soula H, Berry H (2019) Simulation of calcium signaling in fine astrocytic processes: Effect of spatial properties on spontaneous activity. PLoS Comput Biol 15(8):e1006795. https:\/\/doi.org\/10.1371\/journal.pcbi.1006795","journal-title":"PLoS Comput Biol"},{"issue":"1","key":"5055_CR12","doi-asserted-by":"publisher","first-page":"247","DOI":"10.1186\/s12974-023-02909-4","volume":"20","author":"S Kong","year":"2023","unstructured":"Kong S et al (2023) Cell-specific NFIA upregulation promotes epileptogenesis by TRPV4-mediated astrocyte reactivity. J Neuroinflammation 20(1):247. https:\/\/doi.org\/10.1186\/s12974-023-02909-4","journal-title":"J Neuroinflammation"},{"issue":"7","key":"5055_CR13","doi-asserted-by":"publisher","first-page":"1592","DOI":"10.1002\/glia.24358","volume":"71","author":"R Luo","year":"2023","unstructured":"Luo R, Zhou B, Liao P, Zuo Y, Jiang R (2023) Disrupting cortical astrocyte Ca2+ signaling in developing brain induces social deficits and depressive-like behaviors. Glia 71(7):1592\u20131606. https:\/\/doi.org\/10.1002\/glia.24358","journal-title":"Glia"},{"key":"5055_CR14","doi-asserted-by":"publisher","DOI":"10.1007\/s12264-023-01128-4","author":"Y Xia","year":"2023","unstructured":"Xia Y et al (2023) Inflammatory factor IL1\u03b1 induces aberrant astrocyte proliferation in spinal cord injury through the Grin2c\/Ca2+\/CaMK2b pathway. Neurosci Bull. https:\/\/doi.org\/10.1007\/s12264-023-01128-4","journal-title":"Neurosci Bull"},{"issue":"1","key":"5055_CR15","doi-asserted-by":"publisher","first-page":"65","DOI":"10.1093\/brain\/aws286","volume":"136","author":"AM Choo","year":"2013","unstructured":"Choo AM et al (2013) Antagonism of purinergic signalling improves recovery from traumatic brain injury. Brain 136(1):65\u201380. https:\/\/doi.org\/10.1093\/brain\/aws286","journal-title":"Brain"},{"issue":"14","key":"5055_CR16","doi-asserted-by":"publisher","first-page":"2256","DOI":"10.1016\/j.neuron.2021.05.023","volume":"109","author":"J Nagai","year":"2021","unstructured":"Nagai J et al (2021) Specific and behaviorally consequential astrocyte Gq GPCR signaling attenuation in vivo with i\u03b2ARK. Neuron 109(14):2256-2274.e9. https:\/\/doi.org\/10.1016\/j.neuron.2021.05.023","journal-title":"Neuron"},{"key":"5055_CR17","doi-asserted-by":"publisher","unstructured":"Stewart A, Fisher RA (2015) Chapter One - Introduction: G Protein-coupled Receptors and RGS Proteins. In Fisher RA (ed) Progress in Molecular Biology and Translational Science, in RGS Protein Physiology and Pathophysiology, Academic Press, vol 133, pp 1\u201311. https:\/\/doi.org\/10.1016\/bs.pmbts.2015.03.002.","DOI":"10.1016\/bs.pmbts.2015.03.002"},{"issue":"6","key":"5055_CR18","doi-asserted-by":"publisher","first-page":"1076","DOI":"10.1002\/glia.23589","volume":"67","author":"CA Durkee","year":"2019","unstructured":"Durkee CA, Covelo A, Lines J, Kofuji P, Aguilar J, Araque A (2019) Gi\/o protein-coupled receptors inhibit neurons but activate astrocytes and stimulate gliotransmission. Glia 67(6):1076\u20131093. https:\/\/doi.org\/10.1002\/glia.23589","journal-title":"Glia"},{"issue":"2","key":"5055_CR19","doi-asserted-by":"publisher","first-page":"182","DOI":"10.1038\/nn.4201","volume":"19","author":"N Bazargani","year":"2016","unstructured":"Bazargani N, Attwell D (2016) Astrocyte calcium signaling: the third wave. Nat Neurosci 19(2):182\u2013189. https:\/\/doi.org\/10.1038\/nn.4201","journal-title":"Nat Neurosci"},{"issue":"17","key":"5055_CR20","doi-asserted-by":"publisher","first-page":"17","DOI":"10.3390\/ijms241713590","volume":"24","author":"K Ozawa","year":"2023","unstructured":"Ozawa K et al (2023) Astrocytic GPCR-induced Ca2+ signaling is not causally related to local cerebral blood flow changes. Int J Mol Sci 24(17):17. https:\/\/doi.org\/10.3390\/ijms241713590","journal-title":"Int J Mol Sci"},{"issue":"10","key":"5055_CR21","doi-asserted-by":"publisher","first-page":"551","DOI":"10.1038\/s41583-020-0361-8","volume":"21","author":"A Semyanov","year":"2020","unstructured":"Semyanov A, Henneberger C, Agarwal A (2020) Making sense of astrocytic calcium signals - from acquisition to interpretation. Nat Rev Neurosci 21(10):551\u2013564. https:\/\/doi.org\/10.1038\/s41583-020-0361-8","journal-title":"Nat Rev Neurosci"},{"issue":"3","key":"5055_CR22","doi-asserted-by":"publisher","first-page":"531","DOI":"10.1016\/j.neuron.2017.06.029","volume":"95","author":"H Chai","year":"2017","unstructured":"Chai H et al (2017) Neural circuit-specialized astrocytes: transcriptomic, proteomic, morphological, and functional evidence. Neuron 95(3):531-549.e9. https:\/\/doi.org\/10.1016\/j.neuron.2017.06.029","journal-title":"Neuron"},{"issue":"19","key":"5055_CR23","doi-asserted-by":"publisher","first-page":"4967","DOI":"10.1523\/JNEUROSCI.5572-07.2008","volume":"28","author":"J Petravicz","year":"2008","unstructured":"Petravicz J, Fiacco TA, McCarthy KD (2008) Loss of IP3 receptor-dependent Ca2+ increases in hippocampal astrocytes does not affect baseline CA1 pyramidal neuron synaptic activity. J Neurosci 28(19):4967\u20134973. https:\/\/doi.org\/10.1523\/JNEUROSCI.5572-07.2008","journal-title":"J Neurosci"},{"issue":"10","key":"5055_CR24","doi-asserted-by":"publisher","first-page":"872","DOI":"10.1016\/S0960-9822(03)00330-0","volume":"13","author":"W Zeng","year":"2003","unstructured":"Zeng W, Mak D-OD, Li Q, Shin DM, Foskett JK, Muallem S (2003) A new mode of Ca2+ signaling by G protein-coupled receptors: gating of IP3 receptor Ca2+ release channels by G\u03b2\u03b3. Curr Biol 13(10):872\u2013876. https:\/\/doi.org\/10.1016\/S0960-9822(03)00330-0","journal-title":"Curr Biol"},{"issue":"9","key":"5055_CR25","doi-asserted-by":"publisher","first-page":"1126","DOI":"10.1016\/j.chembiol.2011.07.013","volume":"18","author":"M Putyrski","year":"2011","unstructured":"Putyrski M, Schultz C (2011) Switching heterotrimeric G protein subunits with a chemical dimerizer. Chem Biol 18(9):1126\u20131133. https:\/\/doi.org\/10.1016\/j.chembiol.2011.07.013","journal-title":"Chem Biol"},{"issue":"11","key":"5055_CR26","doi-asserted-by":"publisher","first-page":"1020","DOI":"10.1038\/ncb1101-1020","volume":"3","author":"M Schmidt","year":"2001","unstructured":"Schmidt M et al (2001) A new phospholipase-C\u2013calcium signalling pathway mediated by cyclic AMP and a Rap GTPase. Nat Cell Biol 3(11):1020. https:\/\/doi.org\/10.1038\/ncb1101-1020","journal-title":"Nat Cell Biol"},{"key":"5055_CR27","doi-asserted-by":"publisher","first-page":"71","DOI":"10.1016\/j.neuroscience.2020.03.025","volume":"456","author":"P Kofuji","year":"2021","unstructured":"Kofuji P, Araque A (2021) G-protein-coupled receptors in astrocyte-neuron communication. Neuroscience 456:71\u201384. https:\/\/doi.org\/10.1016\/j.neuroscience.2020.03.025","journal-title":"Neuroscience"},{"key":"5055_CR28","doi-asserted-by":"publisher","first-page":"471","DOI":"10.1038\/s41467-020-14378-x","volume":"11","author":"Y Oe","year":"2020","unstructured":"Oe Y et al (2020) Distinct temporal integration of noradrenaline signaling by astrocytic second messengers during vigilance. Nat Commun 11:471. https:\/\/doi.org\/10.1038\/s41467-020-14378-x","journal-title":"Nat Commun"},{"key":"5055_CR29","doi-asserted-by":"publisher","first-page":"1159756","DOI":"10.3389\/fncel.2023.1159756","volume":"17","author":"SH Lee","year":"2023","unstructured":"Lee SH, Mak A, Verheijen MHG (2023) Comparative assessment of the effects of DREADDs and endogenously expressed GPCRs in hippocampal astrocytes on synaptic activity and memory. Front Cell Neurosci 17:1159756. https:\/\/doi.org\/10.3389\/fncel.2023.1159756","journal-title":"Front Cell Neurosci"},{"issue":"6","key":"5055_CR30","doi-asserted-by":"publisher","first-page":"613","DOI":"10.1038\/nn1246","volume":"7","author":"P Bezzi","year":"2004","unstructured":"Bezzi P et al (2004) Astrocytes contain a vesicular compartment that is competent for regulated exocytosis of glutamate. Nat Neurosci 7(6):613. https:\/\/doi.org\/10.1038\/nn1246","journal-title":"Nat Neurosci"},{"issue":"1","key":"5055_CR31","doi-asserted-by":"publisher","first-page":"59","DOI":"10.1016\/j.cell.2018.05.002","volume":"174","author":"A Adamsky","year":"2018","unstructured":"Adamsky A et al (2018) Astrocytic activation generates De Novo neuronal potentiation and memory enhancement. Cell 174(1):59-71.e14. https:\/\/doi.org\/10.1016\/j.cell.2018.05.002","journal-title":"Cell"},{"key":"5055_CR32","doi-asserted-by":"publisher","first-page":"581075","DOI":"10.3389\/fncel.2020.581075","volume":"14","author":"AG Pacholko","year":"2020","unstructured":"Pacholko AG, Wotton CA, Bekar LK (2020) Astrocytes-the ultimate effectors of long-range neuromodulatory networks? Front Cell Neurosci 14:581075. https:\/\/doi.org\/10.3389\/fncel.2020.581075","journal-title":"Front Cell Neurosci"},{"key":"5055_CR33","doi-asserted-by":"publisher","unstructured":"Y. Iwai et al., \u201cTransient Astrocytic Gq Signaling Underlies Remote Memory Enhancement,\u201d Front. Neural Circuits, vol. 15, Mar. 2021, https:\/\/doi.org\/10.3389\/fncir.2021.658343.","DOI":"10.3389\/fncir.2021.658343"},{"issue":"7509","key":"5055_CR34","doi-asserted-by":"publisher","first-page":"348","DOI":"10.1038\/nature13294","volume":"511","author":"S Nabavi","year":"2014","unstructured":"Nabavi S, Fox R, Proulx CD, Lin JY, Tsien RY, Malinow R (2014) Engineering a memory with LTD and LTP. Nature 511(7509):348\u2013352. https:\/\/doi.org\/10.1038\/nature13294","journal-title":"Nature"},{"key":"5055_CR35","doi-asserted-by":"publisher","unstructured":"Moukarzel E, Antoine S, Guinoiseau S, Rubino B, Stinnakre J, Agulhon C (Apr 20 2024) Chronic activation of astrocytic Gq GPCR signaling has causal effects on visual LTP formation: implications for neurodegenerative diseases. bioRxiv. https:\/\/doi.org\/10.1101\/2024.04.16.589763.","DOI":"10.1101\/2024.04.16.589763"},{"issue":"8023","key":"5055_CR36","doi-asserted-by":"publisher","first-page":"209","DOI":"10.1038\/s41586-024-07742-0","volume":"632","author":"T-H Chou","year":"2024","unstructured":"Chou T-H et al (2024) Molecular mechanism of ligand gating and opening of NMDA receptor. Nature 632(8023):209\u2013217. https:\/\/doi.org\/10.1038\/s41586-024-07742-0","journal-title":"Nature"},{"issue":"23","key":"5055_CR37","doi-asserted-by":"publisher","first-page":"4548","DOI":"10.1016\/j.molcel.2022.10.008","volume":"82","author":"T-H Chou","year":"2022","unstructured":"Chou T-H, Kang H, Simorowski N, Traynelis SF, Furukawa H (2022) Structural insights into assembly and function of GluN1-2C, GluN1-2A-2C, and GluN1-2D NMDARs. Mol Cell 82(23):4548-4563.e4. https:\/\/doi.org\/10.1016\/j.molcel.2022.10.008","journal-title":"Mol Cell"},{"issue":"2","key":"5055_CR38","doi-asserted-by":"publisher","first-page":"309","DOI":"10.3390\/ijms20020309","volume":"20","author":"K Skowro\u0144ska","year":"2019","unstructured":"Skowro\u0144ska K, Obara-Michlewska M, Zieli\u0144ska M, Albrecht J (2019) NMDA receptors in astrocytes: in search for roles in neurotransmission and astrocytic homeostasis. Int J Mol Sci 20(2):309. https:\/\/doi.org\/10.3390\/ijms20020309","journal-title":"Int J Mol Sci"},{"issue":"11","key":"5055_CR39","doi-asserted-by":"publisher","first-page":"e14123","DOI":"10.1371\/journal.pone.0014123","volume":"5","author":"M-C Lee","year":"2010","unstructured":"Lee M-C, Ting KK, Adams S, Brew BJ, Chung R, Guillemin GJ (2010) Characterisation of the expression of NMDA receptors in human astrocytes. PLoS ONE 5(11):e14123. https:\/\/doi.org\/10.1371\/journal.pone.0014123","journal-title":"PLoS ONE"},{"issue":"11","key":"5055_CR40","doi-asserted-by":"publisher","first-page":"1877","DOI":"10.1038\/cdd.2015.49","volume":"22","author":"D Jimenez-Blasco","year":"2015","unstructured":"Jimenez-Blasco D, Santofimia-Casta\u00f1o P, Gonzalez A, Almeida A, Bola\u00f1os JP (2015) Astrocyte NMDA receptors\u2019 activity sustains neuronal survival through a Cdk5\u2013Nrf2 pathway. Cell Death Differ 22(11):1877\u20131889. https:\/\/doi.org\/10.1038\/cdd.2015.49","journal-title":"Cell Death Differ"},{"issue":"5","key":"5055_CR41","doi-asserted-by":"publisher","first-page":"e0126314","DOI":"10.1371\/journal.pone.0126314","volume":"10","author":"PP Montes de Oca Balderas Aguilera","year":"2015","unstructured":"Montes de Oca Balderas Aguilera PP (2015) A metabotropic-like flux-independent NMDA receptor regulates Ca2+ exit from endoplasmic reticulum and mitochondrial membrane potential in cultured astrocytes. PLoS One 10(5):e0126314. https:\/\/doi.org\/10.1371\/journal.pone.0126314","journal-title":"PLoS One"},{"issue":"12","key":"5055_CR42","doi-asserted-by":"publisher","first-page":"2124","DOI":"10.1007\/s11064-010-0325-x","volume":"35","author":"Y Zhou","year":"2010","unstructured":"Zhou Y et al (2010) Astrocytes express N-Methyl-D-aspartate receptor subunits in development, ischemia and post-ischemia. Neurochem Res 35(12):2124\u20132134. https:\/\/doi.org\/10.1007\/s11064-010-0325-x","journal-title":"Neurochem Res"},{"issue":"7","key":"5055_CR43","doi-asserted-by":"publisher","first-page":"1270","DOI":"10.1096\/fj.00-0439fje","volume":"15","author":"CG Schipke","year":"2001","unstructured":"Schipke CG, Ohlemeyer C, Matyash M, Nolte C, Kettenmann H, Kirchhoff F (2001) Astrocytes of the mouse neocortex express functional N-methyl-D-aspartate receptors. FASEB J 15(7):1270\u20131272. https:\/\/doi.org\/10.1096\/fj.00-0439fje","journal-title":"FASEB J"},{"issue":"1","key":"5055_CR44","doi-asserted-by":"publisher","first-page":"61","DOI":"10.1007\/s11064-018-2526-7","volume":"44","author":"HA Alsaad","year":"2019","unstructured":"Alsaad HA, DeKorver NW, Mao Z, Dravid SM, Arikkath J, Monaghan DT (2019) In the telencephalon, GluN2C NMDA receptor subunit mRNA is predominately expressed in glial cells and GluN2D mRNA in interneurons. Neurochem Res 44(1):61\u201377. https:\/\/doi.org\/10.1007\/s11064-018-2526-7","journal-title":"Neurochem Res"},{"key":"5055_CR45","doi-asserted-by":"publisher","first-page":"49","DOI":"10.1016\/j.neuroscience.2018.03.011","volume":"380","author":"A Ravikrishnan","year":"2018","unstructured":"Ravikrishnan A, Gandhi PJ, Shelkar GP, Liu J, Pavuluri R, Dravid SM (2018) Region-specific expression of NMDA receptor GluN2C subunit in parvalbumin-positive neurons and astrocytes: Analysis of GluN2C expression using a novel reporter model. Neuroscience 380:49\u201362. https:\/\/doi.org\/10.1016\/j.neuroscience.2018.03.011","journal-title":"Neuroscience"},{"issue":"11","key":"5055_CR46","doi-asserted-by":"publisher","first-page":"907","DOI":"10.1093\/ijnp\/pyab055","volume":"24","author":"GP Shelkar","year":"2021","unstructured":"Shelkar GP, Liu J, Dravid SM (2021) Astrocytic NMDA receptors in the basolateral amygdala contribute to facilitation of fear extinction. Int J Neuropsychopharmacol 24(11):907\u2013919. https:\/\/doi.org\/10.1093\/ijnp\/pyab055","journal-title":"Int J Neuropsychopharmacol"},{"issue":"18","key":"5055_CR47","doi-asserted-by":"publisher","first-page":"3585","DOI":"10.1111\/bph.14568","volume":"176","author":"JS Sadick","year":"2019","unstructured":"Sadick JS, Liddelow SA (2019) Don\u2019t forget astrocytes when targeting Alzheimer\u2019s disease. Br J Pharmacol 176(18):3585\u20133598. https:\/\/doi.org\/10.1111\/bph.14568","journal-title":"Br J Pharmacol"},{"key":"5055_CR48","doi-asserted-by":"publisher","unstructured":"Kirchhoff F (2017) Analysis of Functional NMDA Receptors in Astrocytes. In: Burnashev N, Szepetowski P (eds) NMDA Receptors: Methods and Protocols, New York, NY: Springer, pp 241\u2013251. https:\/\/doi.org\/10.1007\/978-1-4939-7321-7_13","DOI":"10.1007\/978-1-4939-7321-7_13"},{"issue":"29","key":"5055_CR49","doi-asserted-by":"publisher","first-page":"5672","DOI":"10.1523\/JNEUROSCI.0350-22.2022","volume":"42","author":"S Belin","year":"2022","unstructured":"Belin S, Maki BA, Catlin J, Rein BA, Popescu GK (2022) Membrane stretch gates NMDA receptors. J Neurosci 42(29):5672\u20135680. https:\/\/doi.org\/10.1523\/JNEUROSCI.0350-22.2022","journal-title":"J Neurosci"},{"key":"5055_CR50","doi-asserted-by":"publisher","first-page":"1035553","DOI":"10.3389\/fncel.2023.1035553","volume":"17","author":"P Thapaliya","year":"2023","unstructured":"Thapaliya P, Pape N, Rose CR, Ullah G (2023) Modeling the heterogeneity of sodium and calcium homeostasis between cortical and hippocampal astrocytes and its impact on bioenergetics. Front Cell Neurosci 17:1035553. https:\/\/doi.org\/10.3389\/fncel.2023.1035553","journal-title":"Front Cell Neurosci"},{"issue":"14","key":"5055_CR51","doi-asserted-by":"publisher","first-page":"2620","DOI":"10.1523\/JNEUROSCI.2029-18.2019","volume":"39","author":"D Ziemens","year":"2019","unstructured":"Ziemens D, Oschmann F, Gerkau NJ, Rose CR (2019) Heterogeneity of activity-induced sodium transients between astrocytes of the mouse hippocampus and neocortex: mechanisms and consequences. J Neurosci 39(14):2620\u20132634. https:\/\/doi.org\/10.1523\/JNEUROSCI.2029-18.2019","journal-title":"J Neurosci"},{"issue":"19","key":"5055_CR52","doi-asserted-by":"publisher","first-page":"E2685","DOI":"10.1073\/pnas.1523717113","volume":"113","author":"M Letellier","year":"2016","unstructured":"Letellier M et al (2016) Astrocytes regulate heterogeneity of presynaptic strengths in hippocampal networks. Proc Natl Acad Sci U S A 113(19):E2685\u2013E2694. https:\/\/doi.org\/10.1073\/pnas.1523717113","journal-title":"Proc Natl Acad Sci U S A"},{"issue":"8","key":"5055_CR53","doi-asserted-by":"publisher","first-page":"1396","DOI":"10.1002\/glia.23013","volume":"64","author":"VT Cheli","year":"2016","unstructured":"Cheli VT, Santiago Gonz\u00e1lez DA, Smith J, Spreuer V, Murphy GG, Paez PM (2016) L-type voltage-operated calcium channels contribute to astrocyte activation In vitro. Glia 64(8):1396\u20131415. https:\/\/doi.org\/10.1002\/glia.23013","journal-title":"Glia"},{"issue":"12","key":"5055_CR54","doi-asserted-by":"publisher","first-page":"16622","DOI":"10.1096\/fj.202001300R","volume":"34","author":"P Montes de Oca Balderas","year":"2020","unstructured":"Montes de Oca Balderas P, Matus N\u00fa\u00f1ez M, Picones A, Hern\u00e1ndez-Cruz A (2020) \u201cNMDAR in cultured astrocytes: Flux-independent pH sensor and flux-dependent regulator of mitochondria and plasma membrane-mitochondria bridging. FASEB J 34(12):16622\u201316644. https:\/\/doi.org\/10.1096\/fj.202001300R","journal-title":"FASEB J"},{"issue":"1","key":"5055_CR55","doi-asserted-by":"publisher","first-page":"183","DOI":"10.1007\/s10787-020-00760-0","volume":"29","author":"SK Mishra","year":"2021","unstructured":"Mishra SK, Hidau M, Rai S (2021) Memantine and Ibuprofen pretreatment exerts anti-inflammatory effect against streptozotocin-induced astroglial inflammation via modulation of NMDA receptor-associated downstream calcium ion signaling. Inflammopharmacol 29(1):183\u2013192. https:\/\/doi.org\/10.1007\/s10787-020-00760-0","journal-title":"Inflammopharmacol"},{"issue":"8","key":"5055_CR56","doi-asserted-by":"publisher","first-page":"e13437","DOI":"10.1111\/acel.13437","volume":"20","author":"Z Du","year":"2021","unstructured":"Du Z et al (2021) Knockdown of astrocytic Grin2a aggravates \u03b2-amyloid-induced memory and cognitive deficits through regulating nerve growth factor. Aging Cell 20(8):e13437. https:\/\/doi.org\/10.1111\/acel.13437","journal-title":"Aging Cell"},{"key":"5055_CR57","doi-asserted-by":"publisher","first-page":"103197","DOI":"10.1016\/j.redox.2024.103197","volume":"73","author":"SR Sood","year":"2024","unstructured":"Sood SR, Jaiswal V, Kang S-U, Park M, Lee H-J (2024) Nobiletin regulates intracellular Ca2+ levels via IP3R and ameliorates neuroinflammation in A\u03b242-induced astrocytes\u201d. Redox Biol 73:103197. https:\/\/doi.org\/10.1016\/j.redox.2024.103197","journal-title":"Redox Biol"},{"issue":"1","key":"5055_CR58","doi-asserted-by":"publisher","first-page":"271","DOI":"10.1007\/s12640-018-9958-3","volume":"35","author":"K Skowro\u0144ska","year":"2019","unstructured":"Skowro\u0144ska K, Obara-Michlewska M, Czarnecka A, D\u0105browska K, Zieli\u0144ska M, Albrecht J (2019) Persistent overexposure to N-Methyl-d-Aspartate (NMDA) calcium-dependently downregulates glutamine synthetase, Aquaporin 4, and Kir4.1 channel in mouse cortical astrocytes. Neurotox Res 35(1):271\u2013280. https:\/\/doi.org\/10.1007\/s12640-018-9958-3","journal-title":"Neurotox Res"},{"key":"5055_CR59","doi-asserted-by":"publisher","unstructured":"Ahmadpour N et al (2024) Cortical astrocyte N-methyl-D-aspartate receptors influence whisker barrel activity and sensory discrimination in mice. Nat Commun 15. https:\/\/doi.org\/10.1038\/s41467-024-45989-3","DOI":"10.1038\/s41467-024-45989-3"},{"issue":"10","key":"5055_CR60","doi-asserted-by":"publisher","first-page":"2655","DOI":"10.1113\/JP279029","volume":"599","author":"SG Cull-Candy","year":"2021","unstructured":"Cull-Candy SG, Farrant M (2021) Ca2+-permeable AMPA receptors and their auxiliary subunits in synaptic plasticity and disease. J Physiol 599(10):2655\u20132671. https:\/\/doi.org\/10.1113\/JP279029","journal-title":"J Physiol"},{"issue":"4","key":"5055_CR61","doi-asserted-by":"publisher","first-page":"298","DOI":"10.1124\/pharmrev.120.000131","volume":"73","author":"KB Hansen","year":"2021","unstructured":"Hansen KB et al (2021) Structure, function, and pharmacology of glutamate receptor ion channels. Pharmacol Rev 73(4):298\u2013487. https:\/\/doi.org\/10.1124\/pharmrev.120.000131","journal-title":"Pharmacol Rev"},{"issue":"1654","key":"5055_CR62","doi-asserted-by":"publisher","first-page":"20130602","DOI":"10.1098\/rstb.2013.0602","volume":"369","author":"S H\u00f6ft","year":"2014","unstructured":"H\u00f6ft S, Griemsmann S, Seifert G, Steinh\u00e4user C (2014) Heterogeneity in expression of functional ionotropic glutamate and GABA receptors in astrocytes across brain regions: insights from the thalamus. Philos Trans R Soc Lond B Biol Sci 369(1654):20130602. https:\/\/doi.org\/10.1098\/rstb.2013.0602","journal-title":"Philos Trans R Soc Lond B Biol Sci"},{"issue":"9","key":"5055_CR63","doi-asserted-by":"publisher","first-page":"1274","DOI":"10.3390\/biom11091274","volume":"11","author":"C Cervetto","year":"2021","unstructured":"Cervetto C et al (2021) Reactive astrocytosis in a mouse model of chronic polyamine catabolism activation. Biomolecules 11(9):1274. https:\/\/doi.org\/10.3390\/biom11091274","journal-title":"Biomolecules"},{"issue":"7","key":"5055_CR64","doi-asserted-by":"publisher","first-page":"1344","DOI":"10.1002\/glia.23609","volume":"67","author":"Z-W Kou","year":"2019","unstructured":"Kou Z-W et al (2019) Vascular endothelial growth factor increases the function of calcium-impermeable AMPA receptor GluA2 subunit in astrocytes via activation of protein kinase C signaling pathway. Glia 67(7):1344\u20131358. https:\/\/doi.org\/10.1002\/glia.23609","journal-title":"Glia"},{"issue":"1","key":"5055_CR65","doi-asserted-by":"publisher","first-page":"401","DOI":"10.1007\/s00204-017-2018-6","volume":"92","author":"K Umeda","year":"2018","unstructured":"Umeda K, Miyara M, Ishida K, Sanoh S, Ohta S, Kotake Y (2018) Carbofuran causes neuronal vulnerability to glutamate by decreasing GluA2 protein levels in rat primary cortical neurons. Arch Toxicol 92(1):401\u2013409. https:\/\/doi.org\/10.1007\/s00204-017-2018-6","journal-title":"Arch Toxicol"},{"issue":"6095","key":"5055_CR66","doi-asserted-by":"publisher","first-page":"749","DOI":"10.1126\/science.1221140","volume":"337","author":"AS Saab","year":"2012","unstructured":"Saab AS et al (2012) Bergmann glial AMPA receptors are required for fine motor coordination. Science 337(6095):749\u2013753. https:\/\/doi.org\/10.1126\/science.1221140","journal-title":"Science"},{"issue":"17","key":"5055_CR67","doi-asserted-by":"publisher","first-page":"3374","DOI":"10.1523\/JNEUROSCI.0013-19.2020","volume":"40","author":"CL Bender","year":"2020","unstructured":"Bender CL et al (2020) Emotional stress induces structural plasticity in Bergmann Glial Cells via an AC5\u2013CPEB3\u2013GluA1 Pathway. J Neurosci 40(17):3374\u20133384. https:\/\/doi.org\/10.1523\/JNEUROSCI.0013-19.2020","journal-title":"J Neurosci"},{"key":"5055_CR68","doi-asserted-by":"publisher","first-page":"108696","DOI":"10.1016\/j.neuropharm.2021.108696","volume":"197","author":"R Falc\u00f3n-Moya","year":"2021","unstructured":"Falc\u00f3n-Moya R, Rodr\u00edguez-Moreno A (2021) Metabotropic actions of kainate receptors modulating glutamate release. Neuropharmacology 197:108696. https:\/\/doi.org\/10.1016\/j.neuropharm.2021.108696","journal-title":"Neuropharmacology"},{"issue":"7","key":"5055_CR69","doi-asserted-by":"publisher","first-page":"5095","DOI":"10.1007\/s12035-018-1427-8","volume":"56","author":"D Ourdev","year":"2019","unstructured":"Ourdev D, Schmaus A, Kar S (2019) Kainate receptor activation enhances amyloidogenic processing of APP in Astrocytes. Mol Neurobiol 56(7):5095\u20135110. https:\/\/doi.org\/10.1007\/s12035-018-1427-8","journal-title":"Mol Neurobiol"},{"issue":"10\u201311","key":"5055_CR70","doi-asserted-by":"publisher","first-page":"1187","DOI":"10.1016\/s0028-3908(98)00139-7","volume":"37","author":"D Bleakman","year":"1998","unstructured":"Bleakman D, Lodge D (1998) Neuropharmacology of AMPA and kainate receptors. Neuropharmacology 37(10\u201311):1187\u20131204. https:\/\/doi.org\/10.1016\/s0028-3908(98)00139-7","journal-title":"Neuropharmacology"},{"issue":"1","key":"5055_CR71","doi-asserted-by":"publisher","first-page":"3","DOI":"10.1385\/MN:31:1-3:003","volume":"31","author":"Q Wang","year":"2005","unstructured":"Wang Q, Yu S, Simonyi A, Sun GY, Sun AY (2005) Kainic acid-mediated excitotoxicity as a model for neurodegeneration. Mol Neurobiol 31(1):3\u201316. https:\/\/doi.org\/10.1385\/MN:31:1-3:003","journal-title":"Mol Neurobiol"},{"issue":"2","key":"5055_CR72","doi-asserted-by":"publisher","first-page":"292","DOI":"10.1016\/j.neuron.2013.09.045","volume":"80","author":"J Lerma","year":"2013","unstructured":"Lerma J, Marques JM (2013) Kainate receptors in health and disease. Neuron 80(2):292\u2013311. https:\/\/doi.org\/10.1016\/j.neuron.2013.09.045","journal-title":"Neuron"},{"issue":"4","key":"5055_CR73","doi-asserted-by":"publisher","first-page":"1165","DOI":"10.1523\/JNEUROSCI.10-04-01165.1990","volume":"10","author":"A Jensen","year":"1990","unstructured":"Jensen A, Chiu S (1990) Fluorescence measurement of changes in intracellular calcium induced by excitatory amino acids in cultured cortical astrocytes. J Neurosci 10(4):1165\u20131175. https:\/\/doi.org\/10.1523\/JNEUROSCI.10-04-01165.1990","journal-title":"J Neurosci"},{"issue":"1","key":"5055_CR74","doi-asserted-by":"publisher","first-page":"28","DOI":"10.1111\/bpa.12617","volume":"29","author":"A Kodam","year":"2018","unstructured":"Kodam A et al (2018) A role for astrocyte-derived amyloid \u03b2 peptides in the degeneration of neurons in an animal model of temporal lobe epilepsy. Brain Pathol 29(1):28\u201344. https:\/\/doi.org\/10.1111\/bpa.12617","journal-title":"Brain Pathol"},{"key":"5055_CR75","doi-asserted-by":"publisher","unstructured":"Vargas JR, Takahashi DK, Thomson KE, Wilcox KS (2013) The expression of kainate receptor subunits in hippocampal astrocytes following experimentally induced status epilepticus. J Neuropathol Exp Neurol 72(10). https:\/\/doi.org\/10.1097\/NEN.0b013e3182a4b266","DOI":"10.1097\/NEN.0b013e3182a4b266"},{"issue":"2","key":"5055_CR76","doi-asserted-by":"publisher","first-page":"165","DOI":"10.1007\/s12551-024-01184-8","volume":"16","author":"VP Zinchenko","year":"2024","unstructured":"Zinchenko VP, Dolgacheva LP, Tuleukhanov ST (2024) Calcium-permeable AMPA and kainate receptors of GABAergic neurons. Biophys Rev 16(2):165\u2013171. https:\/\/doi.org\/10.1007\/s12551-024-01184-8","journal-title":"Biophys Rev"},{"issue":"3","key":"5055_CR77","doi-asserted-by":"publisher","first-page":"985","DOI":"10.1523\/JNEUROSCI.3389-09.2010","volume":"30","author":"VDJ Bonfardin","year":"2010","unstructured":"Bonfardin VDJ, Fossat P, Theodosis DT, Oliet SHR (2010) Glia-dependent switch of kainate receptor presynaptic action. J Neurosci 30(3):985\u2013995. https:\/\/doi.org\/10.1523\/JNEUROSCI.3389-09.2010","journal-title":"J Neurosci"},{"key":"5055_CR78","doi-asserted-by":"publisher","first-page":"108540","DOI":"10.1016\/j.neuropharm.2021.108540","volume":"196","author":"JD Nair","year":"2021","unstructured":"Nair JD, Wilkinson KA, Henley JM, Mellor JR (2021) Kainate receptors and synaptic plasticity. Neuropharmacology 196:108540. https:\/\/doi.org\/10.1016\/j.neuropharm.2021.108540","journal-title":"Neuropharmacology"},{"key":"5055_CR79","doi-asserted-by":"publisher","first-page":"108699","DOI":"10.1016\/j.neuropharm.2021.108699","volume":"197","author":"C Mulle","year":"2021","unstructured":"Mulle C, Cr\u00e9pel V (2021) Regulation and dysregulation of neuronal circuits by KARs. Neuropharmacology 197:108699. https:\/\/doi.org\/10.1016\/j.neuropharm.2021.108699","journal-title":"Neuropharmacology"},{"issue":"3","key":"5055_CR80","doi-asserted-by":"publisher","first-page":"489","DOI":"10.1111\/bph.15299","volume":"178","author":"P Illes","year":"2021","unstructured":"Illes P et al (2021) Update of P2X receptor properties and their pharmacology: IUPHAR Review 30. Br J Pharmacol 178(3):489\u2013514. https:\/\/doi.org\/10.1111\/bph.15299","journal-title":"Br J Pharmacol"},{"issue":"2","key":"5055_CR81","doi-asserted-by":"publisher","first-page":"659","DOI":"10.1152\/physrev.00043.2006","volume":"87","author":"G Burnstock","year":"2007","unstructured":"Burnstock G (2007) Physiology and pathophysiology of purinergic neurotransmission. Physiol Rev 87(2):659\u2013797. https:\/\/doi.org\/10.1152\/physrev.00043.2006","journal-title":"Physiol Rev"},{"issue":"2","key":"5055_CR82","doi-asserted-by":"publisher","first-page":"1354","DOI":"10.1074\/jbc.M209454200","volume":"278","author":"S Coco","year":"2003","unstructured":"Coco S et al (2003) Storage and release of ATP from astrocytes in culture. J Biol Chem 278(2):1354\u20131362. https:\/\/doi.org\/10.1074\/jbc.M209454200","journal-title":"J Biol Chem"},{"issue":"36","key":"5055_CR83","doi-asserted-by":"publisher","first-page":"E3455","DOI":"10.1073\/pnas.1308088110","volume":"110","author":"M Li","year":"2013","unstructured":"Li M, Silberberg SD, Swartz KJ (2013) Subtype-specific control of P2X receptor channel signaling by ATP and Mg2+. Proc Natl Acad Sci U S A 110(36):E3455\u2013E3463. https:\/\/doi.org\/10.1073\/pnas.1308088110","journal-title":"Proc Natl Acad Sci U S A"},{"issue":"4","key":"5055_CR84","doi-asserted-by":"publisher","first-page":"437","DOI":"10.1085\/jgp.201110647","volume":"138","author":"Z Yan","year":"2011","unstructured":"Yan Z, Khadra A, Sherman A, Stojilkovic SS (2011) Calcium-dependent block of P2X7 receptor channel function is allosteric. J Gen Physiol 138(4):437\u2013452. https:\/\/doi.org\/10.1085\/jgp.201110647","journal-title":"J Gen Physiol"},{"issue":"1","key":"5055_CR85","doi-asserted-by":"publisher","first-page":"51","DOI":"10.1016\/j.neuron.2012.09.024","volume":"76","author":"BS Khakh","year":"2012","unstructured":"Khakh BS, North RA (2012) Neuromodulation by extracellular ATP and P2X receptors in the CNS. Neuron 76(1):51\u201369. https:\/\/doi.org\/10.1016\/j.neuron.2012.09.024","journal-title":"Neuron"},{"key":"5055_CR86","doi-asserted-by":"publisher","unstructured":"Burnstock G, Kennedy C (2011) Chapter 11 - P2X Receptors in Health and Disease. In: Jacobson KA, Linden J (eds) Advances in Pharmacology, in Pharmacology of Purine and Pyrimidine Receptors, Academic Press, vol 61, pp 333\u2013372. https:\/\/doi.org\/10.1016\/B978-0-12-385526-8.00011-4.","DOI":"10.1016\/B978-0-12-385526-8.00011-4"},{"issue":"12","key":"5055_CR87","doi-asserted-by":"publisher","first-page":"2770","DOI":"10.1002\/glia.24450","volume":"71","author":"JB Hjukse","year":"2023","unstructured":"Hjukse JB et al (2023) Increased membrane Ca2+ permeability drives astrocytic Ca2+ dynamics during neuronal stimulation at excitatory synapses. Glia 71(12):2770\u20132781. https:\/\/doi.org\/10.1002\/glia.24450","journal-title":"Glia"},{"key":"5055_CR88","doi-asserted-by":"publisher","unstructured":"Dias L, Madeira D, Dias R, Tom\u00e9 \u00c2R, Cunha RA, Agostinho P (Aug 2022) \u201cA\u03b21\u201342 peptides blunt the adenosine A2A receptor-mediated control of the interplay between P2X7 and P2Y1 receptors mediated calcium responses in astrocytes. Cell Mol Life Sci: CMLS 79(8). https:\/\/doi.org\/10.1007\/s00018-022-04492-y.","DOI":"10.1007\/s00018-022-04492-y"},{"issue":"10","key":"5055_CR89","doi-asserted-by":"publisher","first-page":"1772","DOI":"10.1002\/glia.23001","volume":"64","author":"A Bhattacharya","year":"2016","unstructured":"Bhattacharya A, Biber K (2016) The microglial ATP-gated ion channel P2X7 as a CNS drug target. Glia 64(10):1772\u20131787. https:\/\/doi.org\/10.1002\/glia.23001","journal-title":"Glia"},{"issue":"7","key":"5055_CR90","doi-asserted-by":"publisher","first-page":"575","DOI":"10.1038\/nrd2605","volume":"7","author":"G Burnstock","year":"2008","unstructured":"Burnstock G (2008) Purinergic signalling and disorders of the central nervous system. Nat Rev Drug Discov 7(7):575\u2013590. https:\/\/doi.org\/10.1038\/nrd2605","journal-title":"Nat Rev Drug Discov"},{"issue":"21","key":"5055_CR91","doi-asserted-by":"publisher","first-page":"5473","DOI":"10.1523\/JNEUROSCI.1149-08.2008","volume":"28","author":"U Lalo","year":"2008","unstructured":"Lalo U et al (2008) P2X1 and P2X5 subunits form the functional P2X receptor in mouse cortical astrocytes. J Neurosci 28(21):5473\u20135480. https:\/\/doi.org\/10.1523\/JNEUROSCI.1149-08.2008","journal-title":"J Neurosci"},{"key":"5055_CR92","doi-asserted-by":"publisher","first-page":"164","DOI":"10.1016\/j.brainresbull.2018.07.016","volume":"151","author":"MT Khan","year":"2019","unstructured":"Khan MT, Deussing J, Tang Y, Illes P (2019) Astrocytic rather than neuronal P2X7 receptors modulate the function of the tri-synaptic network in the rodent hippocampus. Brain Res Bull 151:164\u2013173. https:\/\/doi.org\/10.1016\/j.brainresbull.2018.07.016","journal-title":"Brain Res Bull"},{"issue":"5262","key":"5055_CR93","doi-asserted-by":"publisher","first-page":"735","DOI":"10.1126\/science.272.5262.735","volume":"272","author":"A Surprenant","year":"1996","unstructured":"Surprenant A, Rassendren F, Kawashima E, North RA, Buell G (1996) The cytolytic P2Z receptor for extracellular ATP identified as a P2X receptor (P2X7). Science 272(5262):735\u2013738. https:\/\/doi.org\/10.1126\/science.272.5262.735","journal-title":"Science"},{"key":"5055_CR94","doi-asserted-by":"publisher","first-page":"260","DOI":"10.3389\/fncel.2014.00260","volume":"8","author":"BL Fiebich","year":"2014","unstructured":"Fiebich BL, Akter S, Akundi RS (2014) The two-hit hypothesis for neuroinflammation: role of exogenous ATP in modulating inflammation in the brain. Front Cell Neurosci 8:260. https:\/\/doi.org\/10.3389\/fncel.2014.00260","journal-title":"Front Cell Neurosci"},{"issue":"9","key":"5055_CR95","doi-asserted-by":"publisher","first-page":"3794","DOI":"10.1523\/JNEUROSCI.4218-14.2015","volume":"35","author":"Y Hirayama","year":"2015","unstructured":"Hirayama Y, Ikeda-Matsuo Y, Notomi S, Enaida H, Kinouchi H, Koizumi S (2015) Astrocyte-Mediated Ischemic Tolerance. J Neurosci 35(9):3794\u20133805. https:\/\/doi.org\/10.1523\/JNEUROSCI.4218-14.2015","journal-title":"J Neurosci"},{"issue":"11","key":"5055_CR96","doi-asserted-by":"publisher","first-page":"2317","DOI":"10.1002\/jnr.24699","volume":"98","author":"DD Bijeli\u0107","year":"2020","unstructured":"Bijeli\u0107 DD et al (2020) Central nervous system-infiltrated immune cells induce calcium increase in astrocytes via astroglial purinergic signaling. J Neurosci Res 98(11):2317\u20132332. https:\/\/doi.org\/10.1002\/jnr.24699","journal-title":"J Neurosci Res"},{"issue":"3","key":"5055_CR97","doi-asserted-by":"publisher","first-page":"303","DOI":"10.1007\/s11302-023-09957-8","volume":"20","author":"J Kesavan","year":"2024","unstructured":"Kesavan J et al (2024) Functional expression of the ATP-gated P2X7 receptor in human iPSC-derived astrocytes. Purinergic Signalling 20(3):303\u2013309. https:\/\/doi.org\/10.1007\/s11302-023-09957-8","journal-title":"Purinergic Signalling"},{"key":"5055_CR98","doi-asserted-by":"publisher","first-page":"123","DOI":"10.1186\/s43141-021-00224-0","volume":"19","author":"A Ghit","year":"2021","unstructured":"Ghit A, Assal D, Al-Shami AS, Hussein DEE (2021) GABAA receptors: structure, function, pharmacology, and related disorders. J Genet Eng Biotechnol 19:123. https:\/\/doi.org\/10.1186\/s43141-021-00224-0","journal-title":"J Genet Eng Biotechnol"},{"issue":"19","key":"5055_CR99","doi-asserted-by":"publisher","first-page":"9344","DOI":"10.1073\/pnas.89.19.9344","volume":"89","author":"P Bovolin","year":"1992","unstructured":"Bovolin P, Santi MR, Puia G, Costa E, Grayson D (1992) Expression patterns of gamma-aminobutyric acid type A receptor subunit mRNAs in primary cultures of granule neurons and astrocytes from neonatal rat cerebella. Proc Natl Acad Sci 89(19):9344\u20139348. https:\/\/doi.org\/10.1073\/pnas.89.19.9344","journal-title":"Proc Natl Acad Sci"},{"issue":"2","key":"5055_CR100","doi-asserted-by":"publisher","first-page":"83","DOI":"10.1002\/glia.440110203","volume":"11","author":"DD Fraser","year":"1994","unstructured":"Fraser DD, Mudrick-Donnon LA, MacVicar BA (1994) Astrocytic GABA receptors. Glia 11(2):83\u201393. https:\/\/doi.org\/10.1002\/glia.440110203","journal-title":"Glia"},{"issue":"4","key":"5055_CR101","doi-asserted-by":"publisher","first-page":"2720","DOI":"10.1523\/JNEUROSCI.15-04-02720.1995","volume":"15","author":"D Fraser","year":"1995","unstructured":"Fraser D, Duffy S, Angelides K, Perez-Velazquez J, Kettenmann H, MacVicar B (1995) GABAA\/benzodiazepine receptors in acutely isolated hippocampal astrocytes. J Neurosci 15(4):2720\u20132732. https:\/\/doi.org\/10.1523\/JNEUROSCI.15-04-02720.1995","journal-title":"J Neurosci"},{"issue":"1\u20132","key":"5055_CR102","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/0006-8993(87)91349-7","volume":"404","author":"H Kettenmann","year":"1987","unstructured":"Kettenmann H, Backus KH, Schachner M (1987) gamma-Aminobutyric acid opens Cl-channels in cultured astrocytes. Brain Res 404(1\u20132):1\u20139. https:\/\/doi.org\/10.1016\/0006-8993(87)91349-7","journal-title":"Brain Res"},{"issue":"1","key":"5055_CR103","doi-asserted-by":"publisher","first-page":"73","DOI":"10.1016\/0006-8993(94)90177-5","volume":"636","author":"K Rosewater","year":"1994","unstructured":"Rosewater K, Sontheimer H (1994) Fibrous and protoplasmic astrocytes express GABAA receptors that differ in benzodiazepine pharmacology. Brain Res 636(1):73\u201380. https:\/\/doi.org\/10.1016\/0006-8993(94)90177-5","journal-title":"Brain Res"},{"issue":"21","key":"5055_CR104","doi-asserted-by":"publisher","first-page":"13625","DOI":"10.3390\/ijms232113625","volume":"23","author":"I Jim\u00e9nez-Dinamarca","year":"2022","unstructured":"Jim\u00e9nez-Dinamarca I et al (2022) GABAergic regulation of astroglial gliotransmission through Cx43 hemichannels. Int J Mol Sci 23(21):13625. https:\/\/doi.org\/10.3390\/ijms232113625","journal-title":"Int J Mol Sci"},{"issue":"2","key":"5055_CR105","doi-asserted-by":"publisher","first-page":"692","DOI":"10.1002\/epi4.12750","volume":"8","author":"FS Ismail","year":"2023","unstructured":"Ismail FS, Faustmann PM (2023) The potential role of astroglial GABAA receptors in autoimmune encephalitis associated with GABAA receptor antibodies and seizures. Epilepsia Open 8(2):692\u2013701. https:\/\/doi.org\/10.1002\/epi4.12750","journal-title":"Epilepsia Open"},{"issue":"3","key":"5055_CR106","doi-asserted-by":"publisher","first-page":"363","DOI":"10.1002\/glia.22933","volume":"64","author":"L Mariotti","year":"2016","unstructured":"Mariotti L, Losi G, Sessolo M, Marcon I, Carmignoto G (2016) The inhibitory neurotransmitter GABA evokes long-lasting Ca(2+) oscillations in cortical astrocytes. Glia 64(3):363\u2013373. https:\/\/doi.org\/10.1002\/glia.22933","journal-title":"Glia"},{"issue":"4","key":"5055_CR107","doi-asserted-by":"publisher","first-page":"354","DOI":"10.1002\/glia.10336","volume":"45","author":"M D\u2019Ascenzo","year":"2004","unstructured":"D\u2019Ascenzo M, Vairano M, Andreassi C, Navarra P, Azzena GB, Grassi C (2004) Electrophysiological and molecular evidence of L-(Cav1), N- (Cav2.2), and R- (Cav2.3) type Ca2+ channels in rat cortical astrocytes. Glia 45(4):354\u2013363. https:\/\/doi.org\/10.1002\/glia.10336","journal-title":"Glia"},{"issue":"4","key":"5055_CR108","doi-asserted-by":"publisher","first-page":"347","DOI":"10.1002\/glia.10162","volume":"41","author":"I Latour","year":"2003","unstructured":"Latour I, Hamid J, Beedle AM, Zamponi GW, Macvicar BA (2003) Expression of voltage-gated Ca2+ channel subtypes in cultured astrocytes. Glia 41(4):347\u2013353. https:\/\/doi.org\/10.1002\/glia.10162","journal-title":"Glia"},{"key":"5055_CR109","doi-asserted-by":"publisher","first-page":"8","DOI":"10.3389\/fncel.2010.00008","volume":"4","author":"SZ Young","year":"2010","unstructured":"Young SZ, Platel J-C, Nielsen JV, Jensen NA, Bordey A (2010) GABAA Increases Calcium in Subventricular Zone Astrocyte-Like Cells Through L- and T-Type Voltage-Gated Calcium Channels. Front Cell Neurosci 4:8. https:\/\/doi.org\/10.3389\/fncel.2010.00008","journal-title":"Front Cell Neurosci"},{"issue":"12","key":"5055_CR110","doi-asserted-by":"publisher","first-page":"2947","DOI":"10.1002\/glia.24080","volume":"69","author":"U-K Peteri","year":"2021","unstructured":"Peteri U-K et al (2021) Urokinase plasminogen activator mediates changes in human astrocytes modeling fragile X syndrome. Glia 69(12):2947\u20132962. https:\/\/doi.org\/10.1002\/glia.24080","journal-title":"Glia"},{"issue":"4","key":"5055_CR111","doi-asserted-by":"publisher","first-page":"821","DOI":"10.1124\/pr.114.009654","volume":"67","author":"GW Zamponi","year":"2015","unstructured":"Zamponi GW, Striessnig J, Koschak A, Dolphin AC (2015) The physiology, pathology, and pharmacology of voltage-gated calcium channels and their future therapeutic potential. Pharmacol Rev 67(4):821\u2013870. https:\/\/doi.org\/10.1124\/pr.114.009654","journal-title":"Pharmacol Rev"},{"issue":"4","key":"5055_CR112","doi-asserted-by":"publisher","first-page":"1792","DOI":"10.1007\/s12035-020-02273-x","volume":"58","author":"M Dragi\u0107","year":"2021","unstructured":"Dragi\u0107 M et al (2021) Trimethyltin increases intracellular Ca2+ Via L-Type voltage-gated calcium channels and promotes inflammatory phenotype in rat astrocytes In Vitro. Mol Neurobiol 58(4):1792\u20131805. https:\/\/doi.org\/10.1007\/s12035-020-02273-x","journal-title":"Mol Neurobiol"},{"key":"5055_CR113","doi-asserted-by":"publisher","first-page":"176718","DOI":"10.1016\/j.ejphar.2024.176718","volume":"977","author":"R Frank","year":"2024","unstructured":"Frank R et al (2024) Nimodipine inhibits spreading depolarization, ischemic injury, and neuroinflammation in mouse live brain slice preparations. Eur J Pharmacol 977:176718. https:\/\/doi.org\/10.1016\/j.ejphar.2024.176718","journal-title":"Eur J Pharmacol"},{"issue":"1","key":"5055_CR114","doi-asserted-by":"publisher","first-page":"263","DOI":"10.1186\/s12974-023-02948-x","volume":"20","author":"GE Denaroso","year":"2023","unstructured":"Denaroso GE, Smith Z, Angeliu CG, Cheli VT, Wang C, Paez PM (2023) Deletion of voltage-gated calcium channels in astrocytes decreases neuroinflammation and demyelination in a murine model of multiple sclerosis. J Neuroinflammation 20(1):263. https:\/\/doi.org\/10.1186\/s12974-023-02948-x","journal-title":"J Neuroinflammation"},{"key":"5055_CR115","doi-asserted-by":"publisher","first-page":"38","DOI":"10.1016\/j.neuroscience.2023.05.032","volume":"525","author":"M Letellier","year":"2023","unstructured":"Letellier M, Goda Y (2023) Astrocyte Calcium Signaling Shifts the Polarity of Presynaptic Plasticity. Neuroscience 525:38\u201346. https:\/\/doi.org\/10.1016\/j.neuroscience.2023.05.032","journal-title":"Neuroscience"},{"issue":"3","key":"5055_CR116","doi-asserted-by":"publisher","first-page":"e201811998","DOI":"10.1085\/jgp.201811998","volume":"152","author":"E Cao","year":"2020","unstructured":"Cao E (2020) Structural mechanisms of transient receptor potential ion channels. J Gen Physiol 152(3):e201811998. https:\/\/doi.org\/10.1085\/jgp.201811998","journal-title":"J Gen Physiol"},{"issue":"1","key":"5055_CR117","doi-asserted-by":"publisher","first-page":"99","DOI":"10.1111\/j.1748-1716.2010.02217.x","volume":"203","author":"RL Baylie","year":"2011","unstructured":"Baylie RL, Brayden JE (2011) TRPV channels and vascular function. Acta Physiol 203(1):99\u2013116. https:\/\/doi.org\/10.1111\/j.1748-1716.2010.02217.x","journal-title":"Acta Physiol"},{"issue":"12","key":"5055_CR118","doi-asserted-by":"publisher","first-page":"ENEURO.0350-23.","DOI":"10.1523\/ENEURO.0350-23.2023","volume":"10","author":"MJ Patil","year":"2023","unstructured":"Patil MJ et al (2023) A novel Flp reporter mouse shows that TRPA1 expression is largely limited to sensory neuron subsets. Eneuro 10(12):ENEURO.0350-23.2023. https:\/\/doi.org\/10.1523\/ENEURO.0350-23.2023","journal-title":"Eneuro"},{"issue":"7","key":"5055_CR119","doi-asserted-by":"publisher","first-page":"2993","DOI":"10.1007\/s00429-017-1380-8","volume":"222","author":"M Papanikolaou","year":"2017","unstructured":"Papanikolaou M, Lewis A, Butt AM (2017) Store-operated calcium entry is essential for glial calcium signalling in CNS white matter. Brain Struct Funct 222(7):2993\u20133005. https:\/\/doi.org\/10.1007\/s00429-017-1380-8","journal-title":"Brain Struct Funct"},{"issue":"20","key":"5055_CR120","doi-asserted-by":"publisher","first-page":"3386","DOI":"10.1016\/j.cub.2019.08.021","volume":"29","author":"S-J Oh","year":"2019","unstructured":"Oh S-J et al (2019) Ultrasonic Neuromodulation via Astrocytic TRPA1. Curr Biol 29(20):3386-3401.e8. https:\/\/doi.org\/10.1016\/j.cub.2019.08.021","journal-title":"Curr Biol"},{"issue":"17","key":"5055_CR121","doi-asserted-by":"publisher","first-page":"3378","DOI":"10.1016\/j.cub.2020.06.047","volume":"30","author":"M Uchiyama","year":"2020","unstructured":"Uchiyama M et al (2020) O2-Dependent protein internalization underlies astrocytic sensing of acute hypoxia by restricting multimodal TRPA1 channel responses. Curr Biol 30(17):3378-3396.e7. https:\/\/doi.org\/10.1016\/j.cub.2020.06.047","journal-title":"Curr Biol"},{"issue":"29","key":"5055_CR122","doi-asserted-by":"publisher","first-page":"eadh0102","DOI":"10.1126\/sciadv.adh0102","volume":"9","author":"M Kakae","year":"2023","unstructured":"Kakae M et al (2023) The astrocytic TRPA1 channel mediates an intrinsic protective response to vascular cognitive impairment via LIF production. Sci Adv 9(29):eadh0102. https:\/\/doi.org\/10.1126\/sciadv.adh0102","journal-title":"Sci Adv"},{"issue":"1","key":"5055_CR123","doi-asserted-by":"publisher","first-page":"92","DOI":"10.1186\/s12974-016-0557-z","volume":"13","author":"K-I Lee","year":"2016","unstructured":"Lee K-I et al (2016) Role of transient receptor potential ankyrin 1 channels in Alzheimer\u2019s disease. J Neuroinflammation 13(1):92. https:\/\/doi.org\/10.1186\/s12974-016-0557-z","journal-title":"J Neuroinflammation"},{"issue":"1","key":"5055_CR124","doi-asserted-by":"publisher","first-page":"120110059","DOI":"10.1042\/AN20110059","volume":"4","author":"RC Reyes","year":"2012","unstructured":"Reyes RC, Verkhratsky A, Parpura V (2012) Plasmalemmal Na+\/Ca2+ exchanger modulates Ca2+-dependent exocytotic release of glutamate from rat cortical astrocytes. ASN Neuro 4(1):120110059. https:\/\/doi.org\/10.1042\/AN20110059","journal-title":"ASN Neuro"},{"key":"5055_CR125","doi-asserted-by":"publisher","first-page":"3","DOI":"10.1007\/978-3-319-55858-5_1","volume":"981","author":"J Krebs","year":"2017","unstructured":"Krebs J (2017) The Plasma Membrane Calcium Pump (PMCA): regulation of cytosolic Ca2+, genetic diversities and its role in sub-plasma membrane microdomains. Adv Exp Med Biol 981:3\u201321. https:\/\/doi.org\/10.1007\/978-3-319-55858-5_1","journal-title":"Adv Exp Med Biol"},{"key":"5055_CR126","doi-asserted-by":"publisher","first-page":"356","DOI":"10.1111\/j.1749-6632.2002.tb04762.x","volume":"976","author":"MP Blaustein","year":"2002","unstructured":"Blaustein MP, Juhaszova M, Golovina VA, Church PJ, Stanley EF (2002) Na\/Ca exchanger and PMCA localization in neurons and astrocytes: functional implications. Ann N Y Acad Sci 976:356\u2013366. https:\/\/doi.org\/10.1111\/j.1749-6632.2002.tb04762.x","journal-title":"Ann N Y Acad Sci"},{"issue":"1","key":"5055_CR127","doi-asserted-by":"publisher","first-page":"44","DOI":"10.1186\/s40478-021-01146-1","volume":"9","author":"C Pham","year":"2021","unstructured":"Pham C et al (2021) Astrocytes respond to a neurotoxic A\u03b2 fragment with state-dependent Ca2+ alteration and multiphasic transmitter release. Acta Neuropathol Commun 9(1):44. https:\/\/doi.org\/10.1186\/s40478-021-01146-1","journal-title":"Acta Neuropathol Commun"},{"issue":"7","key":"5055_CR128","doi-asserted-by":"publisher","first-page":"1162","DOI":"10.1002\/glia.22671","volume":"62","author":"LW Pappalardo","year":"2014","unstructured":"Pappalardo LW, Samad OA, Black JA, Waxman SG (2014) Voltage-gated sodium channel Nav1.5 contributes to astrogliosis in an in vitro model of glial injury via reverse Na+\/Ca2+ exchange. Glia 62(7):1162\u20131175. https:\/\/doi.org\/10.1002\/glia.22671","journal-title":"Glia"},{"key":"5055_CR129","doi-asserted-by":"publisher","first-page":"102818","DOI":"10.1016\/j.ceca.2023.102818","volume":"116","author":"D Khananshvili","year":"2023","unstructured":"Khananshvili D (2023) Neuronal and astrocyte NCX isoform\/splice variants: How do they participate in Na+ and Ca2+ signalling? Cell Calcium 116:102818. https:\/\/doi.org\/10.1016\/j.ceca.2023.102818","journal-title":"Cell Calcium"},{"key":"5055_CR130","doi-asserted-by":"publisher","first-page":"102137","DOI":"10.1016\/j.ceca.2019.102137","volume":"86","author":"L H\u00e9ja","year":"2020","unstructured":"H\u00e9ja L, Kardos J (2020) NCX activity generates spontaneous Ca2+ oscillations in the astrocytic leaflet microdomain. Cell Calcium 86:102137. https:\/\/doi.org\/10.1016\/j.ceca.2019.102137","journal-title":"Cell Calcium"},{"key":"5055_CR131","doi-asserted-by":"publisher","first-page":"125","DOI":"10.1016\/j.neuint.2018.03.012","volume":"123","author":"I Ib\u00e1\u00f1ez","year":"2019","unstructured":"Ib\u00e1\u00f1ez I, Bartolom\u00e9-Mart\u00edn D, Piniella D, Gim\u00e9nez C, Zafra F (2019) Activity dependent internalization of the glutamate transporter GLT-1 requires calcium entry through the NCX sodium\/calcium exchanger. Neurochem Int 123:125\u2013132. https:\/\/doi.org\/10.1016\/j.neuint.2018.03.012","journal-title":"Neurochem Int"},{"issue":"1","key":"5055_CR132","doi-asserted-by":"publisher","first-page":"109791","DOI":"10.1016\/j.celrep.2021.109791","volume":"37","author":"NJ Benfey","year":"2021","unstructured":"Benfey NJ, Li VJ, Schohl A, Ruthazer ES (2021) Sodium-calcium exchanger mediates sensory-evoked glial calcium transients in the developing retinotectal system. Cell Rep 37(1):109791. https:\/\/doi.org\/10.1016\/j.celrep.2021.109791","journal-title":"Cell Rep"},{"key":"5055_CR133","doi-asserted-by":"publisher","first-page":"102608","DOI":"10.1016\/j.ceca.2022.102608","volume":"105","author":"A Casamassa","year":"2022","unstructured":"Casamassa A et al (2022) In brain post-ischemic plasticity, Na\/Ca+2+ EXCHANGER 1 and Ascl1 Intervene in microglia-dependent conversion of astrocytes into neuronal lineage. Cell Calcium 105:102608. https:\/\/doi.org\/10.1016\/j.ceca.2022.102608","journal-title":"Cell Calcium"},{"issue":"4","key":"5055_CR134","doi-asserted-by":"publisher","first-page":"1383","DOI":"10.1152\/physrev.00020.2014","volume":"95","author":"M Prakriya","year":"2015","unstructured":"Prakriya M, Lewis RS (2015) Store-operated calcium channels. Physiol Rev 95(4):1383\u20131436. https:\/\/doi.org\/10.1152\/physrev.00020.2014","journal-title":"Physiol Rev"},{"issue":"1","key":"5055_CR135","doi-asserted-by":"publisher","first-page":"126","DOI":"10.3390\/cells9010126","volume":"9","author":"JJ Lopez","year":"2020","unstructured":"Lopez JJ, Jardin I, Sanchez-Collado J, Salido GM, Smani T, Rosado JA (2020) TRPC Channels in the SOCE Scenario. Cells 9(1):126. https:\/\/doi.org\/10.3390\/cells9010126","journal-title":"Cells"},{"key":"5055_CR136","doi-asserted-by":"publisher","first-page":"110681","DOI":"10.1016\/j.cellsig.2023.110681","volume":"107","author":"S Shin","year":"2023","unstructured":"Shin S, Gombedza FC, Awuah Boadi E, Yiu AJ, Roy SK, Bandyopadhyay BC (2023) Reduction of TRPC1\/TRPC3 mediated Ca2+-signaling protects oxidative stress-induced COPD. Cell Signal 107:110681. https:\/\/doi.org\/10.1016\/j.cellsig.2023.110681","journal-title":"Cell Signal"},{"issue":"7","key":"5055_CR137","doi-asserted-by":"publisher","first-page":"1327","DOI":"10.1016\/j.cell.2007.11.039","volume":"131","author":"O Brandman","year":"2007","unstructured":"Brandman O, Liou J, Park WS, Meyer T (2007) STIM2 is a feedback regulator that stabilizes basal cytosolic and endoplasmic reticulum Ca2+ levels. Cell 131(7):1327\u20131339. https:\/\/doi.org\/10.1016\/j.cell.2007.11.039","journal-title":"Cell"},{"issue":"9","key":"5055_CR138","doi-asserted-by":"publisher","first-page":"1707","DOI":"10.1113\/JP276550","volume":"598","author":"PS-W Yeung","year":"2020","unstructured":"Yeung PS-W, Yamashita M, Prakriya M (2020) Molecular basis of allosteric Orai1 channel activation by STIM1. J Physiol 598(9):1707\u20131723. https:\/\/doi.org\/10.1113\/JP276550","journal-title":"J Physiol"},{"issue":"582","key":"5055_CR139","doi-asserted-by":"publisher","first-page":"eaaw5450","DOI":"10.1126\/scisignal.aaw5450","volume":"12","author":"AB Toth","year":"2019","unstructured":"Toth AB, Hori K, Novakovic MM, Bernstein NG, Lambot L, Prakriya M (2019) CRAC channels regulate astrocyte Ca2+ signaling and gliotransmitter release to modulate hippocampal GABAergic transmission. Sci Signal 12(582):eaaw5450. https:\/\/doi.org\/10.1126\/scisignal.aaw5450","journal-title":"Sci Signal"},{"key":"5055_CR140","doi-asserted-by":"publisher","first-page":"e66194","DOI":"10.7554\/eLife.66194","volume":"10","author":"S van Dorp","year":"2021","unstructured":"van Dorp S et al (2021) Conformational dynamics of auto-inhibition in the ER calcium sensor STIM1. Elife 10:e66194. https:\/\/doi.org\/10.7554\/eLife.66194","journal-title":"Elife"},{"issue":"1","key":"5055_CR141","doi-asserted-by":"publisher","first-page":"2444","DOI":"10.1038\/s41467-020-16232-6","volume":"11","author":"RE Yoast","year":"2020","unstructured":"Yoast RE et al (2020) The native ORAI channel trio underlies the diversity of Ca2+ signaling events. Nat Commun 11(1):2444. https:\/\/doi.org\/10.1038\/s41467-020-16232-6","journal-title":"Nat Commun"},{"issue":"1","key":"5055_CR142","doi-asserted-by":"publisher","first-page":"42","DOI":"10.5607\/en.2017.26.1.42","volume":"26","author":"J Kwon","year":"2017","unstructured":"Kwon J, An H, Sa M, Won J, Shin JI, Lee CJ (2017) Orai1 and Orai3 in combination with Stim1 mediate the majority of store-operated calcium entry in astrocytes. Exp Neurobiol 26(1):42. https:\/\/doi.org\/10.5607\/en.2017.26.1.42","journal-title":"Exp Neurobiol"},{"issue":"9","key":"5055_CR143","doi-asserted-by":"publisher","first-page":"1666","DOI":"10.1002\/glia.24188","volume":"70","author":"H Nakajima","year":"2022","unstructured":"Nakajima H et al (2022) Orai2 channel regulates prostaglandin E2 production in TNF\u03b1\/IL1\u03b1-stimulated astrocytes. Glia 70(9):1666\u20131680. https:\/\/doi.org\/10.1002\/glia.24188","journal-title":"Glia"},{"issue":"1","key":"5055_CR144","doi-asserted-by":"publisher","first-page":"48","DOI":"10.1007\/s00401-024-02711-3","volume":"147","author":"A Romagnolo","year":"2024","unstructured":"Romagnolo A et al (2024) Astroglial calcium signaling and homeostasis in tuberous sclerosis complex. Acta Neuropathol 147(1):48. https:\/\/doi.org\/10.1007\/s00401-024-02711-3","journal-title":"Acta Neuropathol"},{"issue":"20","key":"5055_CR145","doi-asserted-by":"publisher","first-page":"5151","DOI":"10.3390\/ijms20205151","volume":"20","author":"RP Norante","year":"2019","unstructured":"Norante RP et al (2019) ALS-Associated SOD1(G93A) decreases SERCA pump levels and increases store-operated Ca2+ entry in primary spinal cord astrocytes from a transgenic mouse model. Int J Mol Sci 20(20):5151. https:\/\/doi.org\/10.3390\/ijms20205151","journal-title":"Int J Mol Sci"},{"issue":"9","key":"5055_CR146","doi-asserted-by":"publisher","first-page":"5309","DOI":"10.1007\/s12035-023-03400-0","volume":"60","author":"A Raj","year":"2023","unstructured":"Raj A, Banerjee R, Santhoshkumar R, Sagar C, Datta I (2023) Presence of extracellular alpha-synuclein aggregates trigger astrocytic degeneration through enhanced membrane rigidity and deregulation of store-operated calcium entry (SOCE) into the endoplasmic reticulum. Mol Neurobiol 60(9):5309\u20135329. https:\/\/doi.org\/10.1007\/s12035-023-03400-0","journal-title":"Mol Neurobiol"},{"key":"5055_CR147","doi-asserted-by":"publisher","first-page":"2.29.1","DOI":"10.1002\/cpns.42","volume":"82","author":"N Zhang","year":"2018","unstructured":"Zhang N, Ding S (2018) Imaging of mitochondrial and cytosolic Ca2+ signals in cultured astrocytes. Curr Protoc Neurosci 82:2.29.1-2.29.11. https:\/\/doi.org\/10.1002\/cpns.42","journal-title":"Curr Protoc Neurosci"},{"key":"5055_CR148","doi-asserted-by":"publisher","unstructured":"Aboufares El Alaoui A, Jackson M, Fabri M, de Vivo L, Bellesi M (2021) Characterization of subcellular organelles in cortical perisynaptic astrocytes. Front Cell Neurosci 14. https:\/\/doi.org\/10.3389\/fncel.2020.573944.","DOI":"10.3389\/fncel.2020.573944"},{"key":"5055_CR149","doi-asserted-by":"publisher","first-page":"102383","DOI":"10.1016\/j.ceca.2021.102383","volume":"96","author":"TE Huntington","year":"2021","unstructured":"Huntington TE, Srinivasan R (2021) Astrocytic mitochondria in adult mouse brain slices show spontaneous calcium influx events with unique properties. Cell Calcium 96:102383. https:\/\/doi.org\/10.1016\/j.ceca.2021.102383","journal-title":"Cell Calcium"},{"issue":"11","key":"5055_CR150","doi-asserted-by":"publisher","first-page":"713","DOI":"10.1038\/s41580-018-0052-8","volume":"19","author":"C Giorgi","year":"2018","unstructured":"Giorgi C, Marchi S, Pinton P (2018) The machineries, regulation and cellular functions of mitochondrial calcium. Nat Rev Mol Cell Biol 19(11):713\u2013730. https:\/\/doi.org\/10.1038\/s41580-018-0052-8","journal-title":"Nat Rev Mol Cell Biol"},{"issue":"1","key":"5055_CR151","doi-asserted-by":"publisher","first-page":"63","DOI":"10.1042\/EBC20220094","volume":"67","author":"JV Cabral-Costa","year":"2023","unstructured":"Cabral-Costa JV, Kowaltowski AJ (2023) Mitochondrial Ca2+ handling as a cell signaling hub: lessons from astrocyte function. Essays Biochem 67(1):63\u201375. https:\/\/doi.org\/10.1042\/EBC20220094","journal-title":"Essays Biochem"},{"key":"5055_CR152","doi-asserted-by":"publisher","first-page":"104592","DOI":"10.1016\/j.tiv.2019.104592","volume":"61","author":"Y Miao","year":"2019","unstructured":"Miao Y et al (2019) Evaluation of (-)-epigallocatechin-3-gallate (EGCG)-induced cytotoxicity on astrocytes: A potential mechanism of calcium overloading-induced mitochondrial dysfunction. Toxicol In Vitro 61:104592. https:\/\/doi.org\/10.1016\/j.tiv.2019.104592","journal-title":"Toxicol In Vitro"},{"issue":"12","key":"5055_CR153","doi-asserted-by":"publisher","first-page":"875","DOI":"10.1038\/nmeth.1398","volume":"6","author":"L Tian","year":"2009","unstructured":"Tian L et al (2009) Imaging neural activity in worms, flies and mice with improved GCaMP calcium indicators. Nat Methods 6(12):875\u2013881. https:\/\/doi.org\/10.1038\/nmeth.1398","journal-title":"Nat Methods"},{"issue":"40","key":"5055_CR154","doi-asserted-by":"publisher","first-page":"13819","DOI":"10.1523\/JNEUROSCI.2601-12.2012","volume":"32","author":"J Akerboom","year":"2012","unstructured":"Akerboom J et al (2012) Optimization of a GCaMP calcium indicator for neural activity imaging. J Neurosci 32(40):13819\u201313840. https:\/\/doi.org\/10.1523\/JNEUROSCI.2601-12.2012","journal-title":"J Neurosci"},{"issue":"6","key":"5055_CR155","doi-asserted-by":"publisher","first-page":"457","DOI":"10.1016\/j.ceca.2014.09.008","volume":"56","author":"H Li","year":"2014","unstructured":"Li H, Wang X, Zhang N, Gottipati MK, Parpura V, Ding S (2014) Imaging of mitochondrial Ca2+ dynamics in astrocytes using cell-specific mitochondria-targeted GCaMP5G\/6s: Mitochondrial Ca2+ uptake and cytosolic Ca2+ availability via the endoplasmic reticulum store. Cell Calcium 56(6):457\u2013466. https:\/\/doi.org\/10.1016\/j.ceca.2014.09.008","journal-title":"Cell Calcium"},{"issue":"1","key":"5055_CR156","doi-asserted-by":"publisher","first-page":"113","DOI":"10.1002\/glia.23531","volume":"67","author":"Y Okubo","year":"2019","unstructured":"Okubo Y, Kanemaru K, Suzuki J, Kobayashi K, Hirose K, Iino M (2019) Inositol 1,4,5-trisphosphate receptor type 2-independent Ca2+ release from the endoplasmic reticulum in astrocytes. Glia 67(1):113\u2013124. https:\/\/doi.org\/10.1002\/glia.23531","journal-title":"Glia"},{"issue":"12","key":"5055_CR157","doi-asserted-by":"publisher","first-page":"110133","DOI":"10.1016\/j.celrep.2021.110133","volume":"37","author":"R Serrat","year":"2021","unstructured":"Serrat R et al (2021) Astroglial ER-mitochondria calcium transfer mediates endocannabinoid-dependent synaptic integration. Cell Rep 37(12):110133. https:\/\/doi.org\/10.1016\/j.celrep.2021.110133","journal-title":"Cell Rep"},{"issue":"4","key":"5055_CR158","doi-asserted-by":"publisher","first-page":"791","DOI":"10.1016\/j.cmet.2020.03.005","volume":"31","author":"J G\u04e7bel","year":"2020","unstructured":"G\u04e7bel J et al (2020) Mitochondria-endoplasmic reticulum contacts in reactive astrocytes promote vascular remodeling. Cell Metab 31(4):791-808.e8. https:\/\/doi.org\/10.1016\/j.cmet.2020.03.005","journal-title":"Cell Metab"},{"issue":"4","key":"5055_CR159","doi-asserted-by":"publisher","first-page":"439","DOI":"10.1007\/s00424-020-02364-7","volume":"472","author":"M Rodr\u00edguez-Prados","year":"2020","unstructured":"Rodr\u00edguez-Prados M, Rojo-Ruiz J, Garc\u00eda-Sancho J, Alonso MT (2020) Direct monitoring of ER Ca2+ dynamics reveals that Ca2+ entry induces ER-Ca2+ release in astrocytes. Pflugers Arch - Eur J Physiol 472(4):439\u2013448. https:\/\/doi.org\/10.1007\/s00424-020-02364-7","journal-title":"Pflugers Arch - Eur J Physiol"},{"issue":"10","key":"5055_CR160","doi-asserted-by":"publisher","first-page":"3466","DOI":"10.1016\/j.celrep.2020.02.043","volume":"30","author":"CM King","year":"2020","unstructured":"King CM et al (2020) Local resting Ca2+ controls the scale of astroglial Ca2+ signals. Cell Rep 30(10):3466-3477.e4. https:\/\/doi.org\/10.1016\/j.celrep.2020.02.043","journal-title":"Cell Rep"},{"key":"5055_CR161","doi-asserted-by":"publisher","first-page":"617989","DOI":"10.3389\/fncel.2021.617989","volume":"15","author":"L H\u00e9ja","year":"2021","unstructured":"H\u00e9ja L, Szab\u00f3 Z, P\u00e9ter M, Kardos J (2021) Spontaneous Ca2+ fluctuations arise in thin astrocytic processes with real 3D geometry. Front Cell Neurosci 15:617989. https:\/\/doi.org\/10.3389\/fncel.2021.617989","journal-title":"Front Cell Neurosci"},{"issue":"2","key":"5055_CR162","doi-asserted-by":"publisher","first-page":"246","DOI":"10.1002\/glia.23537","volume":"67","author":"Y-W Wu","year":"2019","unstructured":"Wu Y-W, Gordleeva S, Tang X, Shih P-Y, Dembitskaya Y, Semyanov A (2019) Morphological profile determines the frequency of spontaneous calcium events in astrocytic processes. Glia 67(2):246\u2013262. https:\/\/doi.org\/10.1002\/glia.23537","journal-title":"Glia"},{"key":"5055_CR163","doi-asserted-by":"publisher","unstructured":"Lalo U, Pankratov Y (May 2024) Astrocyte ryanodine receptors facilitate gliotransmission and astroglial modulation of synaptic plasticity. Front Cell Neurosci 18. https:\/\/doi.org\/10.3389\/fncel.2024.1382010","DOI":"10.3389\/fncel.2024.1382010"},{"issue":"27","key":"5055_CR164","doi-asserted-by":"publisher","first-page":"7109","DOI":"10.1523\/JNEUROSCI.4518-15.2016","volume":"36","author":"JC O\u2019Donnell","year":"2016","unstructured":"O\u2019Donnell JC, Jackson JG, Robinson MB (2016) Transient oxygen\/glucose deprivation causes a delayed loss of mitochondria and increases spontaneous calcium signaling in astrocytic processes. J Neurosci 36(27):7109\u20137127. https:\/\/doi.org\/10.1523\/JNEUROSCI.4518-15.2016","journal-title":"J Neurosci"},{"issue":"5","key":"5055_CR165","doi-asserted-by":"publisher","first-page":"985","DOI":"10.1002\/glia.23584","volume":"67","author":"E Montagna","year":"2019","unstructured":"Montagna E et al (2019) In vivo Ca2+ imaging of astrocytic microdomains reveals a critical role of the amyloid precursor protein for mitochondria. Glia 67(5):985\u2013998. https:\/\/doi.org\/10.1002\/glia.23584","journal-title":"Glia"},{"key":"5055_CR166","doi-asserted-by":"publisher","unstructured":"(Mar 2020) NCX activity generates spontaneous Ca2+ oscillations in the astrocytic leaflet microdomain. Cell Calcium 86:102137. https:\/\/doi.org\/10.1016\/j.ceca.2019.102137","DOI":"10.1016\/j.ceca.2019.102137"},{"key":"5055_CR167","doi-asserted-by":"publisher","first-page":"e58952","DOI":"10.7554\/eLife.58952","volume":"9","author":"Z Ma","year":"2020","unstructured":"Ma Z, Freeman MR (2020) TrpML-mediated astrocyte microdomain Ca2+ transients regulate astrocyte\u2013tracheal interactions. eLife 9:e58952. https:\/\/doi.org\/10.7554\/eLife.58952","journal-title":"eLife"},{"key":"5055_CR168","doi-asserted-by":"publisher","first-page":"689268","DOI":"10.3389\/fncel.2021.689268","volume":"15","author":"E Dzyubenko","year":"2021","unstructured":"Dzyubenko E, Prazuch W, Pillath-Eilers M, Polanska J, Hermann DM (2021) Analysing intercellular communication in astrocytic networks using \u2018Astral.\u2019 Front Cell Neurosci 15:689268. https:\/\/doi.org\/10.3389\/fncel.2021.689268","journal-title":"Front Cell Neurosci"},{"issue":"7","key":"5055_CR169","doi-asserted-by":"publisher","first-page":"1581","DOI":"10.3390\/cells10071581","volume":"10","author":"CA Rodr\u00edguez-Arzate","year":"2021","unstructured":"Rodr\u00edguez-Arzate CA, Mart\u00ednez-Mendoza ML, Rocha-Mendoza I, Luna-Palacios Y, Licea-Rodr\u00edguez J, Mart\u00ednez-Torres A (2021) Morphological and calcium signaling alterations of neuroglial cells in cerebellar cortical dysplasia induced by carmustine. Cells 10(7):1581. https:\/\/doi.org\/10.3390\/cells10071581","journal-title":"Cells"},{"issue":"1","key":"5055_CR170","doi-asserted-by":"publisher","first-page":"5","DOI":"10.1038\/s41514-023-00102-8","volume":"9","author":"SM Zarate","year":"2023","unstructured":"Zarate SM, Huntington TE, Bagher P, Srinivasan R (2023) Aging reduces calreticulin expression and alters spontaneous calcium signals in astrocytic endfeet of the mouse dorsolateral striatum. NPJ Aging 9(1):5. https:\/\/doi.org\/10.1038\/s41514-023-00102-8","journal-title":"NPJ Aging"},{"issue":"6","key":"5055_CR171","doi-asserted-by":"publisher","first-page":"1281","DOI":"10.1002\/jnr.25042","volume":"100","author":"CFM Huffels","year":"2022","unstructured":"Huffels CFM, Osborn LM, Cappaert NLM, Hol EM (2022) Calcium signaling in individual APP\/PS1 mouse dentate gyrus astrocytes increases ex vivo with A\u03b2 pathology and age without affecting astrocyte network activity. J Neurosci Res 100(6):1281\u20131295. https:\/\/doi.org\/10.1002\/jnr.25042","journal-title":"J Neurosci Res"},{"key":"5055_CR172","doi-asserted-by":"publisher","first-page":"945737","DOI":"10.3389\/fncel.2022.945737","volume":"16","author":"V Gomez-Godinez","year":"2022","unstructured":"Gomez-Godinez V, Li H, Kuang Y, Liu C, Shi L, Berns MW (2022) A single cell death is disruptive to spontaneous Ca2+ activity in astrocytes. Front Cell Neurosci 16:945737. https:\/\/doi.org\/10.3389\/fncel.2022.945737","journal-title":"Front Cell Neurosci"},{"issue":"5","key":"5055_CR173","doi-asserted-by":"publisher","first-page":"708","DOI":"10.1038\/nn.4001","volume":"18","author":"R Srinivasan","year":"2015","unstructured":"Srinivasan R et al (2015) Ca2+ signaling in astrocytes from IP3R2\u2212\/\u2212 mice in brain slices and during startle responses in vivo. Nat Neurosci 18(5):708\u2013717. https:\/\/doi.org\/10.1038\/nn.4001","journal-title":"Nat Neurosci"},{"issue":"3","key":"5055_CR174","doi-asserted-by":"publisher","first-page":"587","DOI":"10.1016\/j.neuron.2016.12.034","volume":"93","author":"A Agarwal","year":"2017","unstructured":"Agarwal A et al (2017) Transient opening of the mitochondrial permeability transition pore induces microdomain calcium transients in astrocyte processes. Neuron 93(3):587-605.e7. https:\/\/doi.org\/10.1016\/j.neuron.2016.12.034","journal-title":"Neuron"},{"key":"5055_CR175","doi-asserted-by":"publisher","first-page":"248","DOI":"10.3389\/fncel.2018.00248","volume":"12","author":"N Gavrilov","year":"2018","unstructured":"Gavrilov N, Golyagina I, Brazhe A, Scimemi A, Turlapov V, Semyanov A (2018) Astrocytic coverage of dendritic spines, dendritic shafts, and axonal boutons in hippocampal neuropil. Front Cell Neurosci 12:248. https:\/\/doi.org\/10.3389\/fncel.2018.00248","journal-title":"Front Cell Neurosci"},{"key":"5055_CR176","doi-asserted-by":"publisher","first-page":"11","DOI":"10.1016\/j.brainres.2013.04.023","volume":"1516","author":"H Wen","year":"2013","unstructured":"Wen H et al (2013) Spatiotemporal patterns of Gem expression after rat spinal cord injury. Brain Res 1516:11\u201319. https:\/\/doi.org\/10.1016\/j.brainres.2013.04.023","journal-title":"Brain Res"},{"issue":"6838","key":"5055_CR177","doi-asserted-by":"publisher","first-page":"701","DOI":"10.1038\/35079621","volume":"411","author":"P B\u00e9guin","year":"2001","unstructured":"B\u00e9guin P et al (2001) Regulation of Ca2+ channel expression at the cell surface by the small G-protein kir\/Gem. Nature 411(6838):701\u2013706. https:\/\/doi.org\/10.1038\/35079621","journal-title":"Nature"},{"issue":"1","key":"5055_CR178","doi-asserted-by":"publisher","first-page":"96","DOI":"10.1006\/exnr.1999.7041","volume":"157","author":"S Du","year":"1999","unstructured":"Du S et al (1999) Calcium influx and activation of calpain I mediate acute reactive gliosis in injured spinal cord. Exp Neurol 157(1):96\u2013105. https:\/\/doi.org\/10.1006\/exnr.1999.7041","journal-title":"Exp Neurol"},{"issue":"6","key":"5055_CR179","doi-asserted-by":"publisher","first-page":"1180","DOI":"10.1038\/sj.bjp.0704353","volume":"134","author":"H Franke","year":"2001","unstructured":"Franke H, Kr\u00fcgel U, Schmidt R, Grosche J, Reichenbach A, Illes P (2001) P2 receptor-types involved in astrogliosis in vivo. Br J Pharmacol 134(6):1180\u20131189. https:\/\/doi.org\/10.1038\/sj.bjp.0704353","journal-title":"Br J Pharmacol"},{"issue":"8","key":"5055_CR180","doi-asserted-by":"publisher","first-page":"1078","DOI":"10.1002\/jnr.23384","volume":"92","author":"M Xia","year":"2014","unstructured":"Xia M, Zhu Y (2014) Fibronectin enhances spinal cord astrocyte proliferation by elevating P2Y1 receptor expression. J Neurosci Res 92(8):1078\u20131090. https:\/\/doi.org\/10.1002\/jnr.23384","journal-title":"J Neurosci Res"},{"issue":"8","key":"5055_CR181","doi-asserted-by":"publisher","first-page":"1985","DOI":"10.1002\/glia.24378","volume":"71","author":"A Liu","year":"2023","unstructured":"Liu A et al (2023) Celsr2-mediated morphological polarization and functional phenotype of reactive astrocytes in neural repair. Glia 71(8):1985\u20132004. https:\/\/doi.org\/10.1002\/glia.24378","journal-title":"Glia"},{"key":"5055_CR182","doi-asserted-by":"publisher","unstructured":"Malik AR, Willnow TE (Jan. 2019) Excitatory amino acid transporters in physiology and disorders of the central nervous system. Int J Mol Sci 20(22). https:\/\/doi.org\/10.3390\/ijms20225671.","DOI":"10.3390\/ijms20225671"},{"key":"5055_CR183","doi-asserted-by":"publisher","unstructured":"Dematteis G et al (Jan. 2020) Calcineurin controls expression of EAAT1\/GLAST in mouse and human cultured astrocytes through dynamic regulation of protein synthesis and degradation. Int J Mol Sci 21(6). https:\/\/doi.org\/10.3390\/ijms21062213","DOI":"10.3390\/ijms21062213"},{"issue":"3","key":"5055_CR184","doi-asserted-by":"publisher","first-page":"711","DOI":"10.1016\/0896-6273(95)90158-2","volume":"15","author":"FA Chaudhry","year":"1995","unstructured":"Chaudhry FA, Lehre KP, van Lookeren Campagne M, Ottersen OP, Danbolt NC, Storm-Mathisen J (1995) Glutamate transporters in glial plasma membranes: highly differentiated localizations revealed by quantitative ultrastructural immunocytochemistry. Neuron 15(3):711\u2013720. https:\/\/doi.org\/10.1016\/0896-6273(95)90158-2","journal-title":"Neuron"},{"issue":"3 Pt 1","key":"5055_CR185","doi-asserted-by":"publisher","first-page":"1835","DOI":"10.1523\/JNEUROSCI.15-03-01835.1995","volume":"15","author":"KP Lehre","year":"1995","unstructured":"Lehre KP, Levy LM, Ottersen OP, Storm-Mathisen J, Danbolt NC (1995) Differential expression of two glial glutamate transporters in the rat brain: quantitative and immunocytochemical observations. J Neurosci 15(3 Pt 1):1835\u20131853. https:\/\/doi.org\/10.1523\/JNEUROSCI.15-03-01835.1995","journal-title":"J Neurosci"},{"issue":"1","key":"5055_CR186","doi-asserted-by":"publisher","first-page":"204","DOI":"10.1002\/cne.23450","volume":"522","author":"AE Schreiner","year":"2014","unstructured":"Schreiner AE et al (2014) Laminar and subcellular heterogeneity of GLAST and GLT-1 immunoreactivity in the developing postnatal mouse hippocampus. J Comp Neurol 522(1):204\u2013224. https:\/\/doi.org\/10.1002\/cne.23450","journal-title":"J Comp Neurol"},{"issue":"1","key":"5055_CR187","doi-asserted-by":"publisher","first-page":"213","DOI":"10.1111\/j.1471-4159.2010.06589.x","volume":"113","author":"Y-P Liu","year":"2010","unstructured":"Liu Y-P, Yang C-S, Chen M-C, Sun SH, Tzeng S-F (2010) Ca2+-dependent reduction of glutamate aspartate transporter GLAST expression in astrocytes by P2X7 receptor-mediated phosphoinositide 3-kinase signaling. J Neurochem 113(1):213\u2013227. https:\/\/doi.org\/10.1111\/j.1471-4159.2010.06589.x","journal-title":"J Neurochem"},{"issue":"3","key":"5055_CR188","doi-asserted-by":"publisher","first-page":"672","DOI":"10.1016\/j.stemcr.2023.01.005","volume":"18","author":"LD Hachem","year":"2023","unstructured":"Hachem LD, Hong J, Velumian A, Mothe AJ, Tator CH, Fehlings MG (2023) Excitotoxic glutamate levels drive spinal cord ependymal stem cell proliferation and fate specification through CP-AMPAR signaling. Stem Cell Reports 18(3):672\u2013687. https:\/\/doi.org\/10.1016\/j.stemcr.2023.01.005","journal-title":"Stem Cell Reports"},{"issue":"4","key":"5055_CR189","doi-asserted-by":"publisher","first-page":"784","DOI":"10.1016\/j.cell.2020.03.037","volume":"181","author":"P Kitchen","year":"2020","unstructured":"Kitchen P et al (2020) Targeting aquaporin-4 subcellular localization to treat central nervous system edema. Cell 181(4):784-799.e19. https:\/\/doi.org\/10.1016\/j.cell.2020.03.037","journal-title":"Cell"},{"issue":"6","key":"5055_CR190","doi-asserted-by":"publisher","first-page":"1034","DOI":"10.1002\/glia.22981","volume":"64","author":"N Vardjan","year":"2016","unstructured":"Vardjan N et al (2016) Adrenergic activation attenuates astrocyte swelling induced by hypotonicity and neurotrauma. Glia 64(6):1034\u20131049. https:\/\/doi.org\/10.1002\/glia.22981","journal-title":"Glia"},{"issue":"1","key":"5055_CR191","doi-asserted-by":"publisher","first-page":"179","DOI":"10.1016\/S0306-4522(00)00165-2","volume":"99","author":"SK Agrawal","year":"2000","unstructured":"Agrawal SK, Nashmi R, Fehlings MG (2000) Role of L- and N-type calcium channels in the pathophysiology of traumatic spinal cord white matter injury. Neuroscience 99(1):179\u2013188. https:\/\/doi.org\/10.1016\/S0306-4522(00)00165-2","journal-title":"Neuroscience"},{"issue":"6","key":"5055_CR192","doi-asserted-by":"publisher","first-page":"396","DOI":"10.1038\/s41580-022-00562-y","volume":"24","author":"B Zheng","year":"2023","unstructured":"Zheng B, Tuszynski MH (2023) Regulation of axonal regeneration after mammalian spinal cord injury. Nat Rev Mol Cell Biol 24(6):396\u2013413. https:\/\/doi.org\/10.1038\/s41580-022-00562-y","journal-title":"Nat Rev Mol Cell Biol"},{"key":"5055_CR193","doi-asserted-by":"publisher","first-page":"39610","DOI":"10.1038\/srep39610","volume":"7","author":"MM Maneshi","year":"2017","unstructured":"Maneshi MM et al (2017) Mechanical stress activates NMDA receptors in the absence of agonists. Sci Rep 7:39610. https:\/\/doi.org\/10.1038\/srep39610","journal-title":"Sci Rep"},{"issue":"7","key":"5055_CR194","doi-asserted-by":"publisher","first-page":"788","DOI":"10.3390\/ph6070788","volume":"6","author":"G Gurkoff","year":"2013","unstructured":"Gurkoff G, Shahlaie K, Lyeth B, Berman R (2013) Voltage-gated calcium channel antagonists and traumatic brain injury. Pharmaceuticals (Basel) 6(7):788\u2013812. https:\/\/doi.org\/10.3390\/ph6070788","journal-title":"Pharmaceuticals (Basel)"},{"issue":"10","key":"5055_CR195","doi-asserted-by":"publisher","first-page":"1195","DOI":"10.1089\/neu.2008.0635","volume":"25","author":"X Zhao","year":"2008","unstructured":"Zhao X, Gorin FA, Berman RF, Lyeth BG (2008) Differential hippocampal protection when blocking intracellular sodium and calcium entry during traumatic brain injury in rats. J Neurotrauma 25(10):1195\u20131205. https:\/\/doi.org\/10.1089\/neu.2008.0635","journal-title":"J Neurotrauma"},{"issue":"9","key":"5055_CR196","doi-asserted-by":"publisher","first-page":"1535","DOI":"10.1002\/glia.23180","volume":"65","author":"T Belkacemi","year":"2017","unstructured":"Belkacemi T et al (2017) TRPC1- and TRPC3-dependent Ca2+ signaling in mouse cortical astrocytes affects injury-evoked astrogliosis in vivo. Glia 65(9):1535\u20131549. https:\/\/doi.org\/10.1002\/glia.23180","journal-title":"Glia"},{"key":"5055_CR197","doi-asserted-by":"publisher","first-page":"31","DOI":"10.1016\/j.neuroscience.2024.03.002","volume":"545","author":"T Ling","year":"2024","unstructured":"Ling T et al (2024) Purinergic astrocyte signaling driven by TNF-\u03b1 after cannabidiol administration restores normal synaptic remodeling following traumatic brain injury. Neuroscience 545:31\u201346. https:\/\/doi.org\/10.1016\/j.neuroscience.2024.03.002","journal-title":"Neuroscience"},{"issue":"28","key":"5055_CR198","doi-asserted-by":"publisher","first-page":"11612","DOI":"10.1073\/pnas.1300378110","volume":"110","author":"K Kanemaru","year":"2013","unstructured":"Kanemaru K, Kubota J, Sekiya H, Hirose K, Okubo Y, Iino M (2013) Calcium-dependent N-cadherin up-regulation mediates reactive astrogliosis and neuroprotection after brain injury. Proc Natl Acad Sci U S A 110(28):11612\u201311617. https:\/\/doi.org\/10.1073\/pnas.1300378110","journal-title":"Proc Natl Acad Sci U S A"}],"container-title":["Molecular Neurobiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12035-025-05055-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s12035-025-05055-5\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12035-025-05055-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,9]],"date-time":"2025-10-09T07:29:27Z","timestamp":1759994967000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s12035-025-05055-5"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,5,26]]},"references-count":198,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2025,11]]}},"alternative-id":["5055"],"URL":"https:\/\/doi.org\/10.1007\/s12035-025-05055-5","relation":{},"ISSN":["0893-7648","1559-1182"],"issn-type":[{"value":"0893-7648","type":"print"},{"value":"1559-1182","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,5,26]]},"assertion":[{"value":"18 November 2024","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"8 May 2025","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"26 May 2025","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Not Applicable.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics Approval"}},{"value":"Not applicable.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to Participate"}},{"value":"Not applicable.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for Publication"}},{"value":"The authors declare no competing interests.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing Interests"}}]}}