{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,22]],"date-time":"2025-11-22T00:45:42Z","timestamp":1763772342441,"version":"3.45.0"},"reference-count":44,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2025,11,22]],"date-time":"2025-11-22T00:00:00Z","timestamp":1763769600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2025,11,22]],"date-time":"2025-11-22T00:00:00Z","timestamp":1763769600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"funder":[{"name":"Wenzhou Association for Science and Technology","award":["No. jczc31"],"award-info":[{"award-number":["No. jczc31"]}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["No. 82471121"],"award-info":[{"award-number":["No. 82471121"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Mol Neurobiol"],"published-print":{"date-parts":[[2026,1]]},"DOI":"10.1007\/s12035-025-05560-7","type":"journal-article","created":{"date-parts":[[2025,11,22]],"date-time":"2025-11-22T00:43:24Z","timestamp":1763772204000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["FOXP2-Dependent Vulnerability of RGCs Under Acute Ocular Hypertension"],"prefix":"10.1007","volume":"63","author":[{"given":"Meifang","family":"Yan","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Junjian","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zihao","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jieni","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qi","family":"Tang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jialu","family":"Wu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Huateng","family":"Cao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xue","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jie-Guang","family":"Chen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2025,11,22]]},"reference":[{"key":"5560_CR1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms23073935","author":"MS Dias","year":"2022","unstructured":"Dias MS, Luo X, Ribas VT, Petrs-Silva H, Koch JC (2022) The role of axonal transport in glaucoma. Int J Mol Sci. https:\/\/doi.org\/10.3390\/ijms23073935","journal-title":"Int J Mol Sci"},{"issue":"2","key":"5560_CR2","doi-asserted-by":"publisher","first-page":"224","DOI":"10.1080\/02713683.2017.1396617","volume":"43","author":"AA Shpak","year":"2018","unstructured":"Shpak AA, Guekht AB, Druzhkova TA, Kozlova KI, Gulyaeva NV (2018) Brain-derived neurotrophic factor in patients with primary open-angle glaucoma and age-related cataract. Curr Eye Res 43(2):224\u2013231. https:\/\/doi.org\/10.1080\/02713683.2017.1396617","journal-title":"Curr Eye Res"},{"issue":"5","key":"5560_CR3","doi-asserted-by":"publisher","first-page":"701","DOI":"10.1007\/s10517-020-04959-7","volume":"169","author":"SG Kalinichenko","year":"2020","unstructured":"Kalinichenko SG, Matveeva NY, Korobtsov AV (2020) Brain-derived neurotrophic factor (BDNF) as a regulator of apoptosis under conditions of focal experimental stroke. Bull Exp Biol Med 169(5):701\u2013706. https:\/\/doi.org\/10.1007\/s10517-020-04959-7","journal-title":"Bull Exp Biol Med"},{"issue":"3","key":"5560_CR4","first-page":"157","volume":"11","author":"N Takei","year":"1998","unstructured":"Takei N, Nawa H (1998) Roles of neurotrophins on synaptic development and functions in the central nervous system. Hum Cell 11(3):157\u2013165","journal-title":"Hum Cell"},{"issue":"1","key":"5560_CR5","doi-asserted-by":"publisher","first-page":"70","DOI":"10.1002\/jnr.24256","volume":"97","author":"X Wei","year":"2019","unstructured":"Wei X, Cho KS, Thee EF, Jager MJ, Chen DF (2019) Neuroinflammation and microglia in glaucoma: time for a paradigm shift. J Neurosci Res 97(1):70\u201376. https:\/\/doi.org\/10.1002\/jnr.24256","journal-title":"J Neurosci Res"},{"key":"5560_CR6","doi-asserted-by":"publisher","DOI":"10.3389\/fnmol.2019.00036","volume":"12","author":"A Pronin","year":"2019","unstructured":"Pronin A, Pham D, An W, Dvoriantchikova G, Reshetnikova G, Qiao J, Kozhekbaeva Z, Reiser AE, et al. (2019) Inflammasome activation induces pyroptosis in the retina exposed to ocular hypertension injury. Front Mol Neurosci 12:36. https:\/\/doi.org\/10.3389\/fnmol.2019.00036","journal-title":"Front Mol Neurosci"},{"issue":"6","key":"5560_CR7","doi-asserted-by":"publisher","first-page":"701","DOI":"10.1001\/archopht.120.6.701","volume":"120","author":"MA Kass","year":"2002","unstructured":"Kass MA, Heuer DK, Higginbotham EJ, Johnson CA, Keltner JL, Miller JP, Parrish RK, Wilson MR, et al. (2002) The ocular hypertension treatment study: a randomized trial determines that topical ocular hypotensive medication delays or prevents the onset of primary open-angle glaucoma. Arch Ophthalmol 120(6):701\u2013713. https:\/\/doi.org\/10.1001\/archopht.120.6.701","journal-title":"Arch Ophthalmol"},{"issue":"15","key":"5560_CR8","doi-asserted-by":"publisher","first-page":"3513","DOI":"10.1002\/cne.25208","volume":"529","author":"CK Chen","year":"2021","unstructured":"Chen CK, Kiyama T, Weber N, Whitaker CM, Pan P, Badea TC, Massey SC, Mao CA (2021) Characterization of Tbr2-expressing retinal ganglion cells. J Comp Neurol 529(15):3513\u20133532. https:\/\/doi.org\/10.1002\/cne.25208","journal-title":"J Comp Neurol"},{"issue":"1","key":"5560_CR9","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-018-05134-3","volume":"9","author":"BA Rheaume","year":"2018","unstructured":"Rheaume BA, Jereen A, Bolisetty M, Sajid MS, Yang Y, Renna K, Sun L, Robson P, et al. (2018) Single cell transcriptome profiling of retinal ganglion cells identifies cellular subtypes. Nat Commun 9(1):2759. https:\/\/doi.org\/10.1038\/s41467-018-05134-3","journal-title":"Nat Commun"},{"issue":"2","key":"5560_CR10","doi-asserted-by":"publisher","first-page":"1106","DOI":"10.1167\/iovs.12-10791","volume":"54","author":"L Feng","year":"2013","unstructured":"Feng L, Zhao Y, Yoshida M, Chen H, Yang JF, Kim TS, Cang J, Troy JB, et al. (2013) Sustained ocular hypertension induces dendritic degeneration of mouse retinal ganglion cells that depends on cell type and location. Invest Ophthalmol Vis Sci 54(2):1106\u20131117. https:\/\/doi.org\/10.1167\/iovs.12-10791","journal-title":"Invest Ophthalmol Vis Sci"},{"issue":"35","key":"5560_CR11","doi-asserted-by":"publisher","first-page":"9240","DOI":"10.1523\/JNEUROSCI.0940-16.2016","volume":"36","author":"Y Ou","year":"2016","unstructured":"Ou Y, Jo RE, Ullian EM, Wong RO, Della Santina L (2016) Selective vulnerability of specific retinal ganglion cell types and synapses after transient ocular hypertension. J Neurosci 36(35):9240\u20139252. https:\/\/doi.org\/10.1523\/JNEUROSCI.0940-16.2016","journal-title":"J Neurosci"},{"key":"5560_CR12","doi-asserted-by":"publisher","first-page":"43","DOI":"10.1016\/j.exer.2016.06.006","volume":"158","author":"L Della Santina","year":"2017","unstructured":"Della Santina L, Ou Y (2017) Who\u2019s lost first? Susceptibility of retinal ganglion cell types in experimental glaucoma. Exp Eye Res 158:43\u201350. https:\/\/doi.org\/10.1016\/j.exer.2016.06.006","journal-title":"Exp Eye Res"},{"issue":"1","key":"5560_CR13","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-020-71460-6","volume":"10","author":"KB VanderWall","year":"2020","unstructured":"VanderWall KB, Lu B, Alfaro JS, Allsop AR, Carr AS, Wang S, Meyer JS (2020) Differential susceptibility of retinal ganglion cell subtypes in acute and chronic models of injury and disease. Sci Rep 10(1):17359. https:\/\/doi.org\/10.1038\/s41598-020-71460-6","journal-title":"Sci Rep"},{"issue":"5","key":"5560_CR14","doi-asserted-by":"publisher","first-page":"562","DOI":"10.1111\/cxo.13031","volume":"103","author":"AY Wang","year":"2020","unstructured":"Wang AY, Lee PY, Bui BV, Jobling AI, Greferath U, Brandli A, Dixon MA, Findlay Q et al (2020) Potential mechanisms of retinal ganglion cell type-specific vulnerability in glaucoma. Clin Exp Optom 103(5):562\u2013571. https:\/\/doi.org\/10.1111\/cxo.13031","journal-title":"Clin Exp Optom"},{"issue":"12","key":"5560_CR15","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0144341","volume":"10","author":"RH Berry","year":"2015","unstructured":"Berry RH, Qu J, John SW, Howell GR, Jakobs TC (2015) Synapse loss and dendrite remodeling in a mouse model of glaucoma. PLoS ONE 10(12):e0144341. https:\/\/doi.org\/10.1371\/journal.pone.0144341","journal-title":"PLoS ONE"},{"issue":"4","key":"5560_CR16","doi-asserted-by":"publisher","first-page":"365","DOI":"10.1097\/00061198-200208000-00015","volume":"11","author":"JE Morgan","year":"2002","unstructured":"Morgan JE (2002) Retinal ganglion cell shrinkage in glaucoma. J Glaucoma 11(4):365\u2013370. https:\/\/doi.org\/10.1097\/00061198-200208000-00015","journal-title":"J Glaucoma"},{"issue":"4","key":"5560_CR17","doi-asserted-by":"publisher","first-page":"244","DOI":"10.1016\/j.exer.2011.01.014","volume":"92","author":"M Liu","year":"2011","unstructured":"Liu M, Duggan J, Salt TE, Cordeiro MF (2011) Dendritic changes in visual pathways in glaucoma and other neurodegenerative conditions. Exp Eye Res 92(4):244\u2013250. https:\/\/doi.org\/10.1016\/j.exer.2011.01.014","journal-title":"Exp Eye Res"},{"issue":"11","key":"5560_CR18","doi-asserted-by":"publisher","first-page":"2735","DOI":"10.1523\/JNEUROSCI.4443-07.2008","volume":"28","author":"BP Buckingham","year":"2008","unstructured":"Buckingham BP, Inman DM, Lambert W, Oglesby E, Calkins DJ, Steele MR, Vetter ML, Marsh-Armstrong N et al (2008) Progressive ganglion cell degeneration precedes neuronal loss in a mouse model of glaucoma. J Neurosci 28(11):2735\u201344. https:\/\/doi.org\/10.1523\/JNEUROSCI.4443-07.2008","journal-title":"J Neurosci"},{"issue":"7","key":"5560_CR19","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pgen.1002145","volume":"7","author":"SC Vernes","year":"2011","unstructured":"Vernes SC, Oliver PL, Spiteri E, Lockstone HE, Puliyadi R, Taylor JM, Ho J, Mombereau C, et al. (2011) Foxp2 regulates gene networks implicated in neurite outgrowth in the developing brain. PLoS Genet 7(7):e1002145. https:\/\/doi.org\/10.1371\/journal.pgen.1002145","journal-title":"PLoS Genet"},{"issue":"11","key":"5560_CR20","doi-asserted-by":"publisher","first-page":"1513","DOI":"10.1038\/nn.4380","volume":"19","author":"YC Chen","year":"2016","unstructured":"Chen YC, Kuo HY, Bornschein U, Takahashi H, Chen SY, Lu KM, Yang HY, Chen GM, et al. (2016) Foxp2 controls synaptic wiring of corticostriatal circuits and vocal communication by opposing Mef2c. Nat Neurosci 19(11):1513\u20131522. https:\/\/doi.org\/10.1038\/nn.4380","journal-title":"Nat Neurosci"},{"key":"5560_CR21","doi-asserted-by":"publisher","DOI":"10.3389\/fncel.2017.00212","volume":"11","author":"F Oswald","year":"2017","unstructured":"Oswald F, Kloble P, Ruland A, Rosenkranz D, Hinz B, Butter F, Ramljak S, Zechner U et al (2017) The FOXP2-driven network in developmental disorders and neurodegeneration. Front Cell Neurosci 11:212. https:\/\/doi.org\/10.3389\/fncel.2017.00212","journal-title":"Front Cell Neurosci"},{"issue":"9","key":"5560_CR22","doi-asserted-by":"publisher","first-page":"1930","DOI":"10.1016\/j.celrep.2016.04.069","volume":"15","author":"DL Rousso","year":"2016","unstructured":"Rousso DL, Qiao M, Kagan RD, Yamagata M, Palmiter RD, Sanes JR (2016) Two pairs of ON and OFF retinal ganglion cells are defined by intersectional patterns of transcription factor expression. Cell Rep 15(9):1930\u20131944. https:\/\/doi.org\/10.1016\/j.celrep.2016.04.069","journal-title":"Cell Rep"},{"issue":"6","key":"5560_CR23","doi-asserted-by":"publisher","first-page":"1039","DOI":"10.1016\/j.neuron.2019.11.006","volume":"104","author":"NM Tran","year":"2019","unstructured":"Tran NM, Shekhar K, Whitney IE, Jacobi A, Benhar I, Hong G, Yan W, Adiconis X, et al. (2019) Single-cell profiles of retinal ganglion cells differing in resilience to injury reveal neuroprotective genes. Neuron 104(6):1039-1055 e12. https:\/\/doi.org\/10.1016\/j.neuron.2019.11.006","journal-title":"Neuron"},{"key":"5560_CR24","doi-asserted-by":"publisher","first-page":"26","DOI":"10.1016\/j.preteyeres.2016.12.003","volume":"57","author":"X Sun","year":"2017","unstructured":"Sun X, Dai Y, Chen Y, Yu DY, Cringle SJ, Chen J, Kong X, Wang X et al (2017) Primary angle closure glaucoma: what we know and what we don\u2019t know. Prog Retin Eye Res 57:26\u201345. https:\/\/doi.org\/10.1016\/j.preteyeres.2016.12.003","journal-title":"Prog Retin Eye Res"},{"issue":"6","key":"5560_CR25","doi-asserted-by":"publisher","first-page":"931","DOI":"10.1016\/j.molcel.2015.07.027","volume":"59","author":"D Skowronska-Krawczyk","year":"2015","unstructured":"Skowronska-Krawczyk D, Zhao L, Zhu J, Weinreb RN, Cao G, Luo J, Flagg K, Patel S, et al. (2015) P16INK4a upregulation mediated by SIX6 defines retinal ganglion cell pathogenesis in glaucoma. Mol Cell 59(6):931\u201340. https:\/\/doi.org\/10.1016\/j.molcel.2015.07.027","journal-title":"Mol Cell"},{"key":"5560_CR26","first-page":"392","volume":"16","author":"B Gesslein","year":"2010","unstructured":"Gesslein B, Hakansson G, Carpio R, Gustafsson L, Perez MT, Malmsjo M (2010) Mitogen-activated protein kinases in the porcine retinal arteries and neuroretina following retinal ischemia-reperfusion. Mol Vis 16:392\u2013407","journal-title":"Mol Vis"},{"issue":"2","key":"5560_CR27","doi-asserted-by":"publisher","first-page":"313","DOI":"10.1083\/jcb.200506099","volume":"171","author":"TC Jakobs","year":"2005","unstructured":"Jakobs TC, Libby RT, Ben Y, John SW, Masland RH (2005) Retinal ganglion cell degeneration is topological but not cell type specific in DBA\/2J mice. J Cell Biol 171(2):313\u2013325. https:\/\/doi.org\/10.1083\/jcb.200506099","journal-title":"J Cell Biol"},{"key":"5560_CR28","first-page":"2468","volume":"18","author":"H Tsuruga","year":"2012","unstructured":"Tsuruga H, Murata H, Araie M, Aihara M (2012) A model for the easy assessment of pressure-dependent damage to retinal ganglion cells using cyan fluorescent protein-expressing transgenic mice. Mol Vis 18:2468\u20132478","journal-title":"Mol Vis"},{"key":"5560_CR29","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.mcn.2015.12.003","volume":"71","author":"KA Fernandes","year":"2016","unstructured":"Fernandes KA, Bloomsburg SJ, Miller CJ, Billingslea SA, Merrill MM, Burgess RW, Libby RT, Fuerst PG (2016) Novel axon projection after stress and degeneration in the Dscam mutant retina. Mol Cell Neurosci 71:1\u201312. https:\/\/doi.org\/10.1016\/j.mcn.2015.12.003","journal-title":"Mol Cell Neurosci"},{"key":"5560_CR30","doi-asserted-by":"publisher","unstructured":"Hartsock MJ, Cho H, Wu L, Chen WJ, Gong J, Duh EJ (2016) A mouse model of retinal ischemia-reperfusion injury through elevation of intraocular pressure. J Vis Exp (113). https:\/\/doi.org\/10.3791\/54065","DOI":"10.3791\/54065"},{"issue":"8","key":"5560_CR31","doi-asserted-by":"publisher","first-page":"3542","DOI":"10.1093\/brain\/awad090","volume":"146","author":"HY Kuo","year":"2023","unstructured":"Kuo HY, Chen SY, Huang RC, Takahashi H, Lee YH, Pang HY, Wu CH, Graybiel AM et al (2023) Speech- and language-linked FOXP2 mutation targets protein motors in striatal neurons. Brain 146(8):3542\u20133557. https:\/\/doi.org\/10.1093\/brain\/awad090","journal-title":"Brain"},{"issue":"3","key":"5560_CR32","doi-asserted-by":"publisher","first-page":"203","DOI":"10.1038\/s41594-018-0027-7","volume":"25","author":"DA Grotjahn","year":"2018","unstructured":"Grotjahn DA, Chowdhury S, Xu Y, McKenney RJ, Schroer TA, Lander GC (2018) Cryo-electron tomography reveals that dynactin recruits a team of dyneins for processive motility. Nat Struct Mol Biol 25(3):203\u2013207. https:\/\/doi.org\/10.1038\/s41594-018-0027-7","journal-title":"Nat Struct Mol Biol"},{"issue":"7","key":"5560_CR33","first-page":"2538","volume":"56","author":"X Chen","year":"2015","unstructured":"Chen X, Allen K, Linkroum K, Wang D, Consugar M, DelBono E, Wiggs JL (2015) FOXF2 mutations in patients with early-onset glaucoma. Invest Ophthalmol Vis Sci 56(7):2538\u20132538","journal-title":"Invest Ophthalmol Vis Sci"},{"issue":"5","key":"5560_CR34","doi-asserted-by":"publisher","first-page":"1548","DOI":"10.1073\/pnas.86.5.1548","volume":"86","author":"BJ Schnapp","year":"1989","unstructured":"Schnapp BJ, Reese TS (1989) Dynein is the motor for retrograde axonal transport of organelles. Proc Natl Acad Sci U S A 86(5):1548\u20131552. https:\/\/doi.org\/10.1073\/pnas.86.5.1548","journal-title":"Proc Natl Acad Sci U S A"},{"issue":"22","key":"5560_CR35","doi-asserted-by":"publisher","first-page":"2337","DOI":"10.1056\/NEJMoa0802828","volume":"359","author":"SC Vernes","year":"2008","unstructured":"Vernes SC, Newbury DF, Abrahams BS, Winchester L, Nicod J, Groszer M, Alarcon M, Oliver PL et al (2008) A functional genetic link between distinct developmental language disorders. N Engl J Med 359(22):2337\u201345. https:\/\/doi.org\/10.1056\/NEJMoa0802828","journal-title":"N Engl J Med"},{"key":"5560_CR36","doi-asserted-by":"publisher","first-page":"112","DOI":"10.3389\/fnmol.2017.00112","volume":"10","author":"E Mendoza","year":"2017","unstructured":"Mendoza E, Scharff C (2017) Protein-protein interaction among the FoxP family members and their regulation of two target genes, VLDLR and CNTNAP2 in the zebra finch song system. Front Mol Neurosci 10:112. https:\/\/doi.org\/10.3389\/fnmol.2017.00112","journal-title":"Front Mol Neurosci"},{"issue":"5","key":"5560_CR37","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0125633","volume":"10","author":"A Gdalyahu","year":"2015","unstructured":"Gdalyahu A, Lazaro M, Penagarikano O, Golshani P, Trachtenberg JT, Geschwind DH (2015) The autism related protein contactin-associated protein-like 2 (CNTNAP2) stabilizes new spines: an in vivo mouse study. PLoS One 10(5):e0125633. https:\/\/doi.org\/10.1371\/journal.pone.0125633","journal-title":"PLoS One"},{"issue":"9","key":"5560_CR38","doi-asserted-by":"publisher","first-page":"2567","DOI":"10.1016\/j.celrep.2019.05.006","volume":"27","author":"MT Lazaro","year":"2019","unstructured":"Lazaro MT, Taxidis J, Shuman T, Bachmutsky I, Ikrar T, Santos R, Marcello GM, Mylavarapu A, et al. (2019) Reduced prefrontal synaptic connectivity and disturbed oscillatory population dynamics in the CNTNAP2 model of autism. Cell Rep 27(9):2567-2578 e6. https:\/\/doi.org\/10.1016\/j.celrep.2019.05.006","journal-title":"Cell Rep"},{"key":"5560_CR39","first-page":"1395","volume":"18","author":"A Shimizu","year":"2012","unstructured":"Shimizu A, Takano Y, Shi D, Yokokura S, Yokoyama Y, Zheng X, Shiraishi A, Ohashi Y, et al. (2012) Evaluation of CNTNAP2 gene polymorphisms for exfoliation syndrome in Japanese. Mol Vis 18:1395\u2013401","journal-title":"Mol Vis"},{"issue":"2","key":"5560_CR40","doi-asserted-by":"publisher","first-page":"186","DOI":"10.1038\/ejhg.2010.144","volume":"19","author":"M Krumbiegel","year":"2011","unstructured":"Krumbiegel M, Pasutto F, Schlotzer-Schrehardt U, Uebe S, Zenkel M, Mardin CY, Weisschuh N, Paoli D, et al. (2011) Genome-wide association study with DNA pooling identifies variants at CNTNAP2 associated with pseudoexfoliation syndrome. Eur J Hum Genet 19(2):186\u201393. https:\/\/doi.org\/10.1038\/ejhg.2010.144","journal-title":"Eur J Hum Genet"},{"issue":"6","key":"5560_CR41","doi-asserted-by":"publisher","first-page":"434","DOI":"10.3892\/etm.2022.11361","volume":"23","author":"F Yang","year":"2022","unstructured":"Yang F, Xiao Z, Zhang S (2022) FOXP2 regulates thyroid cancer cell proliferation and apoptosis via transcriptional activation of RPS6KA6. Exp Ther Med 23(6):434. https:\/\/doi.org\/10.3892\/etm.2022.11361","journal-title":"Exp Ther Med"},{"key":"5560_CR42","doi-asserted-by":"publisher","DOI":"10.1016\/j.exer.2019.107703","volume":"185","author":"S Daniel","year":"2019","unstructured":"Daniel S, Meyer KJ, Clark AF, Anderson MG, McDowell CM (2019) Effect of ocular hypertension on the pattern of retinal ganglion cell subtype loss in a mouse model of early-onset glaucoma. Exp Eye Res 185:107703. https:\/\/doi.org\/10.1016\/j.exer.2019.107703","journal-title":"Exp Eye Res"},{"key":"5560_CR43","doi-asserted-by":"publisher","DOI":"10.3389\/fcell.2022.956279","volume":"10","author":"ML Tapia","year":"2022","unstructured":"Tapia ML, Nascimento-Dos-Santos G, Park KK (2022) Subtype-specific survival and regeneration of retinal ganglion cells in response to injury. Front Cell Dev Biol 10:956279. https:\/\/doi.org\/10.3389\/fcell.2022.956279","journal-title":"Front Cell Dev Biol"},{"issue":"7186","key":"5560_CR44","doi-asserted-by":"publisher","first-page":"478","DOI":"10.1038\/nature06739","volume":"452","author":"IJ Kim","year":"2008","unstructured":"Kim IJ, Zhang YF, Yamagata M, Meister M, Sanes JR (2008) Molecular identification of a retinal cell type that responds to upward motion. Nature 452(7186):478-U11. https:\/\/doi.org\/10.1038\/nature06739","journal-title":"Nature"}],"container-title":["Molecular Neurobiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12035-025-05560-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s12035-025-05560-7\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12035-025-05560-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,11,22]],"date-time":"2025-11-22T00:43:25Z","timestamp":1763772205000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s12035-025-05560-7"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,11,22]]},"references-count":44,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2026,1]]}},"alternative-id":["5560"],"URL":"https:\/\/doi.org\/10.1007\/s12035-025-05560-7","relation":{},"ISSN":["0893-7648","1559-1182"],"issn-type":[{"value":"0893-7648","type":"print"},{"value":"1559-1182","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,11,22]]},"assertion":[{"value":"14 February 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"18 November 2025","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"22 November 2025","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"This study was carried out in strict compliance with the ARVO Statement for the Care and Use of Laboratory Animals in Ophthalmic and Vision Research. All procedures were approved by the Laboratory Animal Ethics Committee of Wenzhou Medical University (ID Number: xmsq2023-0040).","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics Approval"}},{"value":"Not applicable.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to Participate"}},{"value":"All authors have read the manuscript and provided consent for publication.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for Publication"}},{"value":"The authors declare no competing interests.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"131"}}