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Ziting Kong and Junling Fu contributed to the conceptualization of the study and are co-first authors of this article. Methodology was designed by Huazheng Luo and Canmei Su. Patient recruitment and data collection were performed by Limei Diao, Qianchao He,Hongyu Xu, Xinmei Zhou, Yiliu Xiao, and Cui Qin. Lun Cai served as the sole corresponding author and was primarily responsible for the conceptualization, final revision and approval of the manuscript.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Author Confirmations"}},{"value":"The study protocol was approved by the Ethics Review Committee of the First Affiliated Hospital of Guangxi University of Chinese Medicine (Ethics No.: 2021\u2013048-07). All participants were fully informed of the study procedures and provided written informed consent. The study was registered with the Chinese Clinical Trial Registry (ChiCTR) (Registration No.: ChiCTR2200057994) on 25 March 2022.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics Approval Statement and Patient Consent"}},{"value":"The authors declare no competing interests.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interest"}}],"article-number":"652"}}