{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,24]],"date-time":"2026-01-24T10:23:55Z","timestamp":1769250235482,"version":"3.49.0"},"reference-count":22,"publisher":"Springer Science and Business Media LLC","issue":"S1","license":[{"start":{"date-parts":[[2022,12,16]],"date-time":"2022-12-16T00:00:00Z","timestamp":1671148800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2022,12,16]],"date-time":"2022-12-16T00:00:00Z","timestamp":1671148800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Indian J Otolaryngol Head Neck Surg"],"published-print":{"date-parts":[[2023,4]]},"DOI":"10.1007\/s12070-022-03348-y","type":"journal-article","created":{"date-parts":[[2022,12,16]],"date-time":"2022-12-16T14:05:12Z","timestamp":1671199512000},"page":"181-186","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["The Effect of Hormone Replacement Treatment on Hearing Function in Hypothyroid Patients"],"prefix":"10.1007","volume":"75","author":[{"given":"Arzu","family":"Tatl\u0131p\u0131nar","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"\u0130lkay","family":"Kartal","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0233-0495","authenticated-orcid":false,"given":"Serhan","family":"Keskin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hayriye","family":"K\u00fclbay","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H\u00fclya","family":"G\u00f6z\u00fc","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tanju","family":"G\u00f6k\u00e7eer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2022,12,16]]},"reference":[{"key":"3348_CR1","unstructured":"Freitas MC, Lima LHC (2006) Diagnostico e tratamento do hipotireoidismo. In: Vilar L, (ed), Endocrinologica Clinica. Guanabara Koogan, pp.\u00a0219\u201330"},{"key":"3348_CR2","doi-asserted-by":"publisher","first-page":"786","DOI":"10.1016\/j.clinph.2007.12.008","volume":"119","author":"AR Thornton","year":"2008","unstructured":"Thornton AR, Jarvis SJ (2008) Auditory brainstem response finding in hypothyroid and hyperthyroid disease. Clin Neurophysiol 119:786\u2013790","journal-title":"Clin Neurophysiol"},{"key":"3348_CR3","first-page":"267","volume":"65","author":"N Davis","year":"2006","unstructured":"Davis N, Lunardi C, Shield JP (2006) Sensori-neural deafness and hypothyroidism: autoimmunity causing \u2018pseudo-Pendred syndrome\u2019. Horm Res 65:267\u2013268","journal-title":"Horm Res"},{"key":"3348_CR4","doi-asserted-by":"publisher","first-page":"317","DOI":"10.1017\/S0022215100071929","volume":"84","author":"SD Stephens","year":"1970","unstructured":"Stephens SD (1970) Temporary treshold drift in myxoedema. J Laryngol Otol 84:317\u2013321","journal-title":"J Laryngol Otol"},{"key":"3348_CR5","doi-asserted-by":"publisher","first-page":"982","DOI":"10.1288\/00005537-198508000-00020","volume":"95","author":"R Ben-Tovim","year":"1985","unstructured":"Ben-Tovim R, Zohar Y, Zohiar S, Laurian N, Laurian L (1985) Auditory brain stem response in experimentally induced hypothyroidism in albino rats. Laryngoscope 95:982\u2013986","journal-title":"Laryngoscope"},{"key":"3348_CR6","doi-asserted-by":"publisher","first-page":"302","DOI":"10.1288\/00005537-198903000-00012","volume":"99","author":"M Vanasse","year":"1989","unstructured":"Vanasse M, Fisher C, Berthez\u00e8ne F, Roux Y, Volman G, Mornex R (1989) Normal brainstem auditory evoked potentials in adult hypothyroidism. Laryngoscope 99:302\u2013306","journal-title":"Laryngoscope"},{"key":"3348_CR7","doi-asserted-by":"publisher","first-page":"110","DOI":"10.1017\/S0954422413000061","volume":"26","author":"A Melse-Boonstra","year":"2013","unstructured":"Melse-Boonstra A, Mackenzie I (2013) Iodine deficiency, thyroid function and hearing deficit: a review. Nutr Res Rev 26:110\u2013117","journal-title":"Nutr Res Rev"},{"key":"3348_CR8","doi-asserted-by":"publisher","first-page":"39046","DOI":"10.1074\/jbc.M103385200","volume":"276","author":"M Knipper","year":"2001","unstructured":"Knipper M, Richardson G, Mack A, M\u00fcller M, Goodyear R, Limberger A et al (2001) Thyroid hormone deficient period prior to the onset of hearing is associated with reduced levels of \u03b2-tectorin protein in the tectorial membrane. Implications for hearing loss. J Biol Chem 276:39046\u201339052","journal-title":"J Biol Chem"},{"key":"3348_CR9","doi-asserted-by":"publisher","first-page":"1593","DOI":"10.1210\/me.2007-0085","volume":"21","author":"KR Johnson","year":"2007","unstructured":"Johnson KR, Marden CC, Ward-Bailey P, Gagnon LH, Bronson RT, Donahue LR (2007) Congenital hypothyroidism, dwarfism, and hearing impairment caused by a missense mutation in the mouse dual oxidase 2 gene, Duox2. Mol Endocrinol 21:1593\u20131602","journal-title":"Mol Endocrinol"},{"key":"3348_CR10","doi-asserted-by":"crossref","unstructured":"McCarrison R (1908) Observation on endemic cretenism in the Chitral and Gilgit Valleys. Lancet ii: 1275-80","DOI":"10.1016\/S0140-6736(01)62987-8"},{"key":"3348_CR11","doi-asserted-by":"publisher","first-page":"1262","DOI":"10.1210\/jcem-67-6-1262","volume":"67","author":"SC Boyages","year":"1988","unstructured":"Boyages SC, Halpern JP, Marbley GF, Eastman CJ, Morris J, Collins J et al (1988) A comparative study of neurological and myxedematous endemic cretenism in Western China. J Clin Endocrinol Metab 67:1262\u20131271","journal-title":"J Clin Endocrinol Metab"},{"key":"3348_CR12","first-page":"2792","volume":"64","author":"IH Friedman","year":"1964","unstructured":"Friedman IH (1964) Deafness in myxedema. NY State J Med 64:2792\u20132793","journal-title":"NY State J Med"},{"key":"3348_CR13","doi-asserted-by":"publisher","first-page":"343","DOI":"10.1097\/00005537-199903000-00001","volume":"109","author":"Z Mra","year":"1999","unstructured":"Mra Z, Wax MK (1999) Effects of acute thyroxin depletion on hearing in humans. Laryngoscope 109:343\u2013350","journal-title":"Laryngoscope"},{"key":"3348_CR14","doi-asserted-by":"publisher","first-page":"221","DOI":"10.1002\/lary.5540740205","volume":"74","author":"JT Post","year":"1964","unstructured":"Post JT (1964) Hypothyroid deafness. A clinical study of sensorineural deafness associated with hypothyroidism. Laryngoscope 74:221\u2013232","journal-title":"Laryngoscope"},{"key":"3348_CR15","doi-asserted-by":"publisher","first-page":"2082","DOI":"10.1288\/00005537-197712000-00014","volume":"87","author":"PL Bhatia","year":"1977","unstructured":"Bhatia PL, Gupta OP, Agrawal MK, Mishr SK (1977) Audiological and vestibular function tests in hypothyroidism. Laryngoscope 87:2082\u20132089","journal-title":"Laryngoscope"},{"key":"3348_CR16","doi-asserted-by":"publisher","first-page":"679","DOI":"10.1017\/S0022215100091271","volume":"95","author":"MZ Himelfarb","year":"1981","unstructured":"Himelfarb MZ, Lakretz T, Gold S, Shanon E (1981) Auditory brain stem responses in thyroid dysfunction. J Laryngol Otol 95:679\u2013686","journal-title":"J Laryngol Otol"},{"key":"3348_CR17","doi-asserted-by":"crossref","first-page":"478","DOI":"10.1590\/S1808-86942010000400012","volume":"76","author":"KTP Dos Santos","year":"2010","unstructured":"Dos Santos KTP, Dias NH, da Silva Mazeto GMF, de Carvalho LR, Lapate RL, Martins RHG (2010) Audiologic evaluation in patients with acquired hypothyroidism. Braz J Otorhinolaryngol 76:478\u2013484","journal-title":"Braz J Otorhinolaryngol"},{"key":"3348_CR18","first-page":"375","volume":"1","author":"AE Howarth","year":"1907","unstructured":"Howarth AE, Lloyd HE (1907) Perceptive deafness in hypothyroidism. Br Med J 1:375","journal-title":"Br Med J"},{"key":"3348_CR19","doi-asserted-by":"publisher","first-page":"621","DOI":"10.1007\/s11845-010-0579-y","volume":"179","author":"DM Comer","year":"2010","unstructured":"Comer DM, McConnell EM (2010) Hypothyroid-associated sensorineuronal deafness. Ir J Med Sci 179:621\u2013622","journal-title":"Ir J Med Sci"},{"key":"3348_CR20","doi-asserted-by":"publisher","first-page":"1","DOI":"10.3109\/00016487509124264","volume":"79","author":"M Rubinstein","year":"1975","unstructured":"Rubinstein M, Perlstein TP, Hildesheimer M (1975) Cochlear action potentials in experimentally induced hypothyroidism in guinea pigs. Acta Otolaryngol 79:1\u201310","journal-title":"Acta Otolaryngol"},{"key":"3348_CR21","doi-asserted-by":"publisher","first-page":"83","DOI":"10.3109\/00016488909107396","volume":"108","author":"VT Anand","year":"1989","unstructured":"Anand VT, Mann SBS, Dash RJ, Mehra YN (1989) Auditory investigations in hypothyroidism. Acta Otolaryngol 108:83\u201387","journal-title":"Acta Otolaryngol"},{"key":"3348_CR22","doi-asserted-by":"publisher","first-page":"229","DOI":"10.1210\/endo-11-3-229","volume":"11","author":"RC Moehling","year":"1927","unstructured":"Moehling RC (1927) Vertigo and deafness associated with hypothyroidism. Endocrinology 11:229","journal-title":"Endocrinology"}],"container-title":["Indian Journal of Otolaryngology and Head & Neck Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12070-022-03348-y.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s12070-022-03348-y\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12070-022-03348-y.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,16]],"date-time":"2023-05-16T17:24:22Z","timestamp":1684257862000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s12070-022-03348-y"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,12,16]]},"references-count":22,"journal-issue":{"issue":"S1","published-print":{"date-parts":[[2023,4]]}},"alternative-id":["3348"],"URL":"https:\/\/doi.org\/10.1007\/s12070-022-03348-y","relation":{},"ISSN":["2231-3796","0973-7707"],"issn-type":[{"value":"2231-3796","type":"print"},{"value":"0973-7707","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,12,16]]},"assertion":[{"value":"8 November 2022","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"1 December 2022","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"16 December 2022","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors assert that all procedures contributing to this work comply with the ethical standards of the relevant national and institutional guidelines on human experimentation (please name) and with the Helsinki Declaration of 1975, as revised in 2008.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with ethical standards"}},{"value":"None.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"The study protocol was approved by Local Ethical Committee before study.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical Approval"}},{"value":"Written informed consent was obtained from all patients.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Informed Consent"}}]}}