{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,17]],"date-time":"2026-10-17T10:42:53Z","timestamp":1792233773809,"version":"4.4.0"},"reference-count":20,"publisher":"Springer Science and Business Media LLC","issue":"3","license":[{"start":{"date-parts":[[2025,2,13]],"date-time":"2025-02-13T00:00:00Z","timestamp":1739404800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2025,2,13]],"date-time":"2025-02-13T00:00:00Z","timestamp":1739404800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Indian J Otolaryngol Head Neck Surg"],"published-print":{"date-parts":[[2025,3]]},"DOI":"10.1007\/s12070-025-05375-x","type":"journal-article","created":{"date-parts":[[2025,2,13]],"date-time":"2025-02-13T18:40:55Z","timestamp":1739472055000},"page":"1542-1551","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Margin Shrinkage in Oral Squamous Cell Carcinoma: A Prospective Observational Study"],"prefix":"10.1007","volume":"77","author":[{"ORCID":"https:\/\/orcid.org\/0009-0004-2209-8843","authenticated-orcid":false,"given":"Advait A.","family":"Vaidya","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7554-7674","authenticated-orcid":false,"given":"Samir","family":"Gupta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8251-1941","authenticated-orcid":false,"given":"Archana Chirag","family":"Buch","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4993-5144","authenticated-orcid":false,"given":"Prasant","family":"Chandra","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-3752-0236","authenticated-orcid":false,"given":"Tejus V.","family":"Nagireddy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2025,2,13]]},"reference":[{"issue":"3","key":"5375_CR1","doi-asserted-by":"publisher","first-page":"229","DOI":"10.3322\/caac.21834","volume":"74","author":"F Bray","year":"2024","unstructured":"Bray F, Laversanne M, Sung H, Ferlay J, Siegel RL, Soerjomataram I, Jemal A (2024) Global cancer statistics 2022: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin 74(3):229\u2013263. https:\/\/doi.org\/10.3322\/caac.21834","journal-title":"CA Cancer J Clin"},{"key":"5375_CR2","unstructured":"Board WC of TE (2020) Soft tissue and bone tumours. WHO Classification of Tumours"},{"key":"5375_CR3","doi-asserted-by":"publisher","first-page":"107","DOI":"10.1002\/hed.2890010203","volume":"1","author":"KG Looser","year":"1978","unstructured":"Looser KG, Shah JP, Strong EW (1978) The significance of \u2018positive\u2019 margins in surgically resected epidermoid carcinomas. Head Neck Surg 1:107\u2013111","journal-title":"Head Neck Surg"},{"key":"5375_CR4","doi-asserted-by":"publisher","first-page":"447","DOI":"10.1016\/j.ijom.2003.10.015","volume":"33","author":"AF Kovacs","year":"2004","unstructured":"Kovacs AF (2004) Relevance of positive margins in case of adjuvant therapy of oral cancer. Int J Oral Maxillofac Surg 33:447\u2013453","journal-title":"Int J Oral Maxillofac Surg"},{"key":"5375_CR5","doi-asserted-by":"publisher","first-page":"720","DOI":"10.1002\/hed.2890060303","volume":"6","author":"B Vikram","year":"1984","unstructured":"Vikram B, Strong EW, Shah JP et al (1984) Failure at the primary site following multimodality treatment in advanced head and neck cancer. Head Neck Surg 6:720\u2013723","journal-title":"Head Neck Surg"},{"key":"5375_CR6","doi-asserted-by":"publisher","first-page":"410","DOI":"10.1016\/S0002-9610(05)80555-0","volume":"160","author":"TR Loree","year":"1990","unstructured":"Loree TR, Strong EW (1990) Significance of positive margins in oral cavity squamous carcinoma. Am J Surg 160:410\u2013414","journal-title":"Am J Surg"},{"key":"5375_CR7","doi-asserted-by":"publisher","first-page":"314","DOI":"10.1016\/S1010-5182(05)80339-7","volume":"19","author":"LA Ravasz","year":"1991","unstructured":"Ravasz LA, Slootweg PJ, Hordijk GJ et al (1991) The status of the resection margin as a prognostic factor in the treatment of head and neck carcinoma. J Craniomaxillofac Surg 19:314\u2013318","journal-title":"J Craniomaxillofac Surg"},{"key":"5375_CR8","doi-asserted-by":"publisher","first-page":"37","DOI":"10.1111\/j.1365-2273.1993.tb00807.x","volume":"18","author":"JA Cook","year":"1993","unstructured":"Cook JA, Jones AS, Phillips DE et al (1993) Implications of tumor in resection margins following surgical treatment of squamous cell carcinoma of the head and neck. Clin Otolaryngol 18:37\u201341","journal-title":"Clin Otolaryngol"},{"key":"5375_CR9","doi-asserted-by":"publisher","first-page":"500","DOI":"10.1016\/S1368-8375(01)00092-6","volume":"38","author":"PJ Slootweg","year":"2002","unstructured":"Slootweg PJ, Hordijk GJ, Schade Y et al (2002) Treatment failure and margin status in head and neck cancer. A critical view on the potential value of molecular pathology. Oral Oncol 38:500\u2013503","journal-title":"Oral Oncol"},{"key":"5375_CR10","doi-asserted-by":"publisher","first-page":"281","DOI":"10.1002\/(SICI)1097-0347(199707)19:4<281::AID-HED6>3.0.CO;2-X","volume":"19","author":"RE Johnson","year":"1997","unstructured":"Johnson RE, Sigman JD, Funk GF et al (1997) Quantification of surgical margin shrinkage in the oral cavity. Head Neck 19:281\u2013286","journal-title":"Head Neck"},{"issue":"2","key":"5375_CR11","doi-asserted-by":"publisher","first-page":"131","DOI":"10.1002\/jso.20285","volume":"91","author":"RC Mistry","year":"2005","unstructured":"Mistry RC, Qureshi SS, Kumaran C (2005) Post-resection mucosal margin shrinkage in oral cancer: quantification and significance. J Surg Oncol 91(2):131\u2013133. https:\/\/doi.org\/10.1002\/jso.20285","journal-title":"J Surg Oncol"},{"issue":"3","key":"5375_CR12","doi-asserted-by":"publisher","first-page":"523","DOI":"10.1016\/j.joms.2007.08.040","volume":"66","author":"A Cheng","year":"2008","unstructured":"Cheng A, Cox D, Schmidt BL (2008) Oral squamous cell carcinoma margin discrepancy after resection and pathologic processing. J Oral Maxillofac Surg 66(3):523\u2013529. https:\/\/doi.org\/10.1016\/j.joms.2007.08.040","journal-title":"J Oral Maxillofac Surg"},{"issue":"6","key":"5375_CR13","doi-asserted-by":"publisher","first-page":"2152","DOI":"10.1097\/SCS.0000000000001150","volume":"25","author":"O Egemen","year":"2014","unstructured":"Egemen O, Bing\u00f6l D, Orman \u00c7, Sayilgan AT, \u00d6zkaya \u00d6, Akan M (2014) Quantification of the surgical margin shrinkage in lip cancer: determining the relation between the surgical and histopathologic margins. J Craniofac Surg 25(6):2152\u20132155. https:\/\/doi.org\/10.1097\/SCS.0000000000001150","journal-title":"J Craniofac Surg"},{"issue":"4","key":"5375_CR14","doi-asserted-by":"publisher","first-page":"475","DOI":"10.1016\/j.jcms.2015.01.009","volume":"43","author":"HA El-Fol","year":"2015","unstructured":"El-Fol HA, Noman SA, Beheiri MG, Khalil AM, Kamel MM (2015) Significance of post-resection tissue shrinkage on surgical margins of oral squamous cell carcinoma. J Craniomaxillofac Surg 43(4):475\u2013482. https:\/\/doi.org\/10.1016\/j.jcms.2015.01.009","journal-title":"J Craniomaxillofac Surg"},{"issue":"6","key":"5375_CR15","doi-asserted-by":"publisher","first-page":"660","DOI":"10.1016\/j.amjoto.2017.08.011","volume":"38","author":"LA Umstattd","year":"2017","unstructured":"Umstattd LA, Mills JC, Critchlow WA, Renner GJ, Zitsch RP 3rd (2017) Shrinkage in oral squamous cell carcinoma: an analysis of tumor and margin measurements in vivo, post-resection, and post-formalin fixation. Am J Otolaryngol 38(6):660\u2013662. https:\/\/doi.org\/10.1016\/j.amjoto.2017.08.011","journal-title":"Am J Otolaryngol"},{"issue":"5","key":"5375_CR16","doi-asserted-by":"publisher","DOI":"10.7759\/cureus.15329","volume":"13","author":"C Burns","year":"2021","unstructured":"Burns C, Gorina FM (2021) An analysis of tumor margin shrinkage in the surgical resection of squamous cell carcinoma of the oral cavity. Cureus 13(5):e15329. https:\/\/doi.org\/10.7759\/cureus.15329","journal-title":"Cureus"},{"issue":"Supplement I-II","key":"5375_CR17","doi-asserted-by":"publisher","first-page":"127","DOI":"10.33899\/ijvs.2021.131918.2023","volume":"35","author":"HB Al-Sabaawy","year":"2021","unstructured":"Al-Sabaawy HB, Rahawi AM, Al-Mahmood SS (2021) Standard techniques for formalin-fixed paraffin-embedded tissue: a pathologist\u2019s perspective. Iraqi J Vet Sci 35(Supplement I-III):127\u2013135. https:\/\/doi.org\/10.33899\/ijvs.2021.131918.2023","journal-title":"Iraqi J Vet Sci"},{"issue":"6","key":"5375_CR18","doi-asserted-by":"publisher","first-page":"1293","DOI":"10.1016\/j.joms.2016.11.024","volume":"75","author":"TB Pangare","year":"2017","unstructured":"Pangare TB, Waknis PP, Bawane SS, Patil MN, Wadhera S, Patowary PB (2017) Effect of formalin fixation on surgical margins in patients with oral squamous cell carcinoma. J Oral Maxillofac Surg 75(6):1293\u20131298. https:\/\/doi.org\/10.1016\/j.joms.2016.11.024","journal-title":"J Oral Maxillofac Surg"},{"issue":"1","key":"5375_CR19","doi-asserted-by":"publisher","first-page":"9","DOI":"10.1186\/s40463-020-00483-w","volume":"50","author":"J Solomon","year":"2021","unstructured":"Solomon J, Hinther A, Matthews TW, Nakoneshny SC, Hart R, Dort JC, Chandarana SP (2021) The impact of close surgical margins on recurrence in oral squamous cell carcinoma. J Otolaryngol Head Neck Surg 50(1):9. https:\/\/doi.org\/10.1186\/s40463-020-00483-w","journal-title":"J Otolaryngol Head Neck Surg"},{"issue":"1","key":"5375_CR20","doi-asserted-by":"publisher","first-page":"38","DOI":"10.1186\/s40463-022-00584-8","volume":"51","author":"J Fowler","year":"2022","unstructured":"Fowler J, Campanile Y, Warner A, Laxague F, Fnais N, Fung K, Mendez A, MacNeil D, Yoo J, Palma D, Nichols A (2022) Surgical margins of the oral cavity: is 5 mm really necessary? J Otolaryngol Head Neck Surg 51(1):38. https:\/\/doi.org\/10.1186\/s40463-022-00584-8","journal-title":"J Otolaryngol Head Neck Surg"}],"container-title":["Indian Journal of Otolaryngology and Head &amp; Neck Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12070-025-05375-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s12070-025-05375-x\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12070-025-05375-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,3,14]],"date-time":"2025-03-14T16:59:36Z","timestamp":1741971576000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s12070-025-05375-x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,2,13]]},"references-count":20,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2025,3]]}},"alternative-id":["5375"],"URL":"https:\/\/doi.org\/10.1007\/s12070-025-05375-x","relation":{},"ISSN":["2231-3796","0973-7707"],"issn-type":[{"value":"2231-3796","type":"print"},{"value":"0973-7707","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,2,13]]},"assertion":[{"value":"25 November 2024","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"27 January 2025","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"13 February 2025","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"None.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflicts of interest"}}]}}