{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,27]],"date-time":"2026-09-27T14:51:17Z","timestamp":1790520677390,"version":"4.1.0"},"reference-count":36,"publisher":"Springer Science and Business Media LLC","issue":"3","license":[{"start":{"date-parts":[[2010,8,3]],"date-time":"2010-08-03T00:00:00Z","timestamp":1280793600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Hepatol Int"],"published-print":{"date-parts":[[2010,9]]},"DOI":"10.1007\/s12072-010-9203-5","type":"journal-article","created":{"date-parts":[[2010,8,2]],"date-time":"2010-08-02T18:43:17Z","timestamp":1280774597000},"page":"608-614","source":"Crossref","is-referenced-by-count":26,"title":["Occult hepatitis B in blood donors in Indonesia: altered antigenicity of the hepatitis B virus surface protein"],"prefix":"10.1007","volume":"4","author":[{"given":"Meta D.","family":"Thedja","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martono","family":"Roni","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alida R.","family":"Harahap","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nurjati C.","family":"Siregar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Susan I.","family":"Ie","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David H.","family":"Muljono","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2010,8,3]]},"reference":[{"key":"9203_CR1","unstructured":"World Health Organization. Hepatitis B vaccines: weekly epidemiological record. WHO annual report. Switzerland; 2009, 84:405\u2013420"},{"key":"9203_CR2","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1007\/s12072-008-9080-3","volume":"2","author":"YF Liaw","year":"2008","unstructured":"Liaw YF, Leung N, Kao JH, Piratvisuth T, Gane E, Han KH, Guan R, Lau GKK, Locarnini S. Asian\u2013Pacific consensus statement on the management of chronic hepatitis B: a 2008 update. Hepatol Int 2008;2:263\u2013283","journal-title":"Hepatol Int"},{"key":"9203_CR3","doi-asserted-by":"crossref","first-page":"1379","DOI":"10.1056\/NEJM197806222982502","volume":"298","author":"JH Hoofnagle","year":"1978","unstructured":"Hoofnagle JH, Seeff LB, Bales ZB, Zimmerman HJ. Type B hepatitis after transfusion with blood containing antibody to hepatitis B core antigen. N Engl J Med 1978;298:1379\u20131383","journal-title":"N Engl J Med"},{"key":"9203_CR4","doi-asserted-by":"crossref","first-page":"1022","DOI":"10.1016\/j.jhep.2008.02.016","volume":"48","author":"S Levicnik-Stezinar","year":"2008","unstructured":"Levicnik-Stezinar S, Rahne-Potokar U, Candotti D, Lelie N, Allain JP. Anti-HBs positive occult hepatitis B virus carrier blood infectious in two transfusion recipients. J Hepatol 2008;48:1022\u20131025","journal-title":"J Hepatol"},{"key":"9203_CR5","doi-asserted-by":"crossref","first-page":"652","DOI":"10.1016\/j.jhep.2008.07.014","volume":"49","author":"G Raimondo","year":"2008","unstructured":"Raimondo G, Allain JP, Brunetto MR, Buendia MA, Chen DS, Colombo M, Craxi A, Donato F, Ferrari C, Gaeta GB, Gerlich WH, Levrero M, Locarnini S, Michalak T, Mondelli MU, Pawlotsky JM, Pollicino T, Prati D, Puoti M, Samuel D, Shouval D, Smedile A, Squadrito G, Trepo C, Villa E, Will H, Zanetti AR, Zoulim F. Statements from the Taormina expert meeting on occult hepatitis B virus infection. J Hepatol 2008;49:652\u2013657","journal-title":"J Hepatol"},{"key":"9203_CR6","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1111\/j.0042-9007.2004.00406.x","volume":"86","author":"JP Allain","year":"2004","unstructured":"Allain JP. Occult hepatitis B virus infection: implications in transfusion. Vox Sang 2004;86:83\u201391","journal-title":"Vox Sang"},{"key":"9203_CR7","doi-asserted-by":"crossref","first-page":"479","DOI":"10.1016\/S1473-3099(02)00345-6","volume":"2","author":"M Torbenson","year":"2002","unstructured":"Torbenson M, Thomas DL. Occult hepatitis B. Lancet Infect Dis 2002;2:479\u2013486","journal-title":"Lancet Infect Dis"},{"key":"9203_CR8","doi-asserted-by":"crossref","first-page":"1664","DOI":"10.3324\/haematol.11224","volume":"92","author":"P Manzini","year":"2007","unstructured":"Manzini P, Girotto M, Borsotti R, Giachino O, Guaschino R, Lanteri M, Testa D, Ghiazza P, Vacchini M, Danielle F, Pizzi A, Valpreda C, Castagno F, Curti F, Magistroni P, Abate ML, Smedile A, Rizzetto M. Italian blood donors with anti-HBc and occult hepatitis B infection. Haematologica 2007;92:1664\u20131670","journal-title":"Haematologica"},{"issue":"Suppl 1","key":"9203_CR9","doi-asserted-by":"crossref","first-page":"S15","DOI":"10.1016\/S1386-6532(05)80005-8","volume":"34","author":"I Chemin","year":"2005","unstructured":"Chemin I, Trepo C. Clinical impact of occult HBV infections. J Clin Virol 2005;34(Suppl 1):S15\u2013S21","journal-title":"J Clin Virol"},{"key":"9203_CR10","doi-asserted-by":"crossref","first-page":"264","DOI":"10.1203\/00006450-199209000-00002","volume":"32","author":"H Okamoto","year":"1992","unstructured":"Okamoto H, Yano K, Nozaki Y, Matsui A, Miyazaki H, Yamamoyo K, Tsuda F, Machida A, Mishiro S. Mutation within the S gene of hepatitis B virus transmitted from mothers to babies immunized with hepatitis B immunoglobulin and vaccine. Pediatric Res 1992;32:264\u2013268","journal-title":"Pediatric Res"},{"key":"9203_CR11","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1111\/j.1423-0410.1992.tb02495.x","volume":"63","author":"H Iizuka","year":"1992","unstructured":"Iizuka H, Ohmura K, Ishijima A, Satoh K, Tanaka T, Tsuda F, Okamoto H, Miyakawa Y, Mayumi M. Correlation between anti-HBc titers and HBV DNA in blood units without detectable HBsAg. Vox Sang 1992;63:107\u2013111","journal-title":"Vox Sang"},{"key":"9203_CR12","unstructured":"Okamoto H, Nishizawa T. Non-B Non-C Non-G hepatitis virus gene, polynucleotide, polypeptide, virion, method for separating virion, and method for detecting virus; 1992. http:\/\/www.freepatentsonline.com\/EP1010759.html (with permission)"},{"key":"9203_CR13","doi-asserted-by":"crossref","first-page":"2313","DOI":"10.1007\/s007050050463","volume":"143","author":"K Takahashi","year":"1998","unstructured":"Takahashi K, Akahane Y, Hino K, Ohta Y, Mishiro S. Hepatitis B virus genomic sequence in the circulation of hepatocellular carcinoma patients: comparative analysis of 40 full-length isolates. Arch Virol 1998;143:2313\u20132326","journal-title":"Arch Virol"},{"key":"9203_CR14","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1038\/339237a0","volume":"339","author":"S Kwok","year":"1989","unstructured":"Kwok S, Higuchi R. Avoiding false positives with PCR. Nature 1989;339:237\u2013238","journal-title":"Nature"},{"key":"9203_CR15","first-page":"95","volume":"41","author":"TA Hall","year":"1999","unstructured":"Hall TA. BioEdit: a user-friendly biological sequence alignment editor and analysis program for Windows 95\/98\/NT. Nucl Acids Symp 1999;41:95\u201398","journal-title":"Nucl Acids Symp"},{"key":"9203_CR16","unstructured":"Sastrosoewignjo RI, Omi S, Okamoto H, Mayumi M, Rustam M, Sujudi T. The complete nucleotide sequence of HBV DNA clone of subtype adw (pMND122) from Menado in Sulawesi Island, Indonesia. ICMR Ann 1987;7:51\u201360."},{"issue":"7","key":"9203_CR17","doi-asserted-by":"crossref","first-page":"1047","DOI":"10.1007\/s00705-009-0406-9","volume":"154","author":"Mulyanto","year":"2009","unstructured":"Mulyanto, Depamede SN, Surayah K, Tsuda F, Ichiyama K, Takahashi M, Okamoto H. A nationwide molecular epidemiological study on hepatitis B virus in Indonesia: identification of two novel subgenotypes, B8 and C7. Arch Virol 2009;154(7):1047\u20131059","journal-title":"Arch Virol"},{"key":"9203_CR18","first-page":"181","volume":"4","author":"BA Jameson","year":"1988","unstructured":"Jameson BA, Wolf H. The antigenic index: a novel algorithm for predicting antigenic determinants. Cabios 1988;4:181\u2013186","journal-title":"Cabios"},{"key":"9203_CR19","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1002\/hep.510270133","volume":"27","author":"MG Ghany","year":"1998","unstructured":"Ghany MG, Ayola B, Villamil FG, Gish RG, Rojter S, Vierling JM, Lok AS. Hepatitis B Virus mutants in liver transplant recipients who were reinfected despite Hepatitis B Immune Globulin prophylaxis. Hepatology 1998;27:213\u2013221","journal-title":"Hepatology"},{"key":"9203_CR20","doi-asserted-by":"crossref","first-page":"751","DOI":"10.1053\/jhep.2001.22166","volume":"33","author":"LJ Stuvyer","year":"2001","unstructured":"Stuvyer LJ, Locarnini SA, Lok A, Richman DD, Carman WF, Dienstag JL, Schinazi RF. The HEP DART IC. Nomenclature for antiviral-resistant human Hepatitis B Virus mutations in the polymerase region. Hepatology 2001;33:751\u2013757","journal-title":"Hepatology"},{"key":"9203_CR21","doi-asserted-by":"crossref","first-page":"1592","DOI":"10.1046\/j.1537-2995.2002.00274.x","volume":"42","author":"JT Wang","year":"2002","unstructured":"Wang JT, Lee CZ, Chen PJ, Wang TH, Chen DS. Transfusion-transmitted HBV infection in an endemic area: the necessity of more sensitive screening for HBV carriers. Transfusion 2002;42:1592\u20131517","journal-title":"Transfusion"},{"key":"9203_CR22","doi-asserted-by":"crossref","first-page":"S419","DOI":"10.1111\/j.1440-1746.2004.03728.x","volume":"19","author":"M Khan","year":"2004","unstructured":"Khan M, Dong JJ, Acharya SK, Dhagwahdorj Y, Abbas Z, Jafri SMW, Mulyono DH, Tozun N, Sarin SK. Hepatology issues in Asia: perspectives from regional leaders. J Gastroenterol Hepatol 2004;19:S419\u2013S430","journal-title":"J Gastroenterol Hepatol"},{"key":"9203_CR23","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1111\/j.1537-2995.2004.04279.x","volume":"45","author":"S Owusu-Ofori","year":"2005","unstructured":"Owusu-Ofori S, Temple J, Sarkodie F, Anokwa M, Candotti D, Allain JP. Predonation screening of blood donors with rapid test: implementation and efficacy of a novel approach to blood safety in resource-poor settings. Transfusion 2005;45:133\u2013140","journal-title":"Transfusion"},{"issue":"9","key":"9203_CR24","doi-asserted-by":"crossref","first-page":"1093","DOI":"10.1046\/j.1537-2995.2001.41091093.x","volume":"41","author":"H Yotsuyanagi","year":"2001","unstructured":"Yotsuyanagi H, Yasuda K, Moriya K, Shintani Y, Fujie H, Tsutsumi T, Nojiri N, Juji T, Hoshino H, Shimoda K, Hino K, Kimura S, Iino S, Koike K. Frequent presence of HBV in the sera of HBsAg-negative, anti-HBc-positive blood donors. Transfusion 2001;41(9):1093\u20131099","journal-title":"Transfusion"},{"key":"9203_CR25","doi-asserted-by":"crossref","first-page":"469","DOI":"10.1007\/s12072-007-9017-2","volume":"1","author":"AM El-Sherif","year":"2007","unstructured":"El-Sherif AM, Abou-Shady MA, Al-Hiatmy MA, Al-Bahrawy AM, Motawea EA. Screening for hepatitis B virus infection in Egyptian blood donors negative for hepatitis B surface antigen. Hepatol Int 2007;1:469\u2013470","journal-title":"Hepatol Int"},{"key":"9203_CR26","doi-asserted-by":"crossref","first-page":"1001","DOI":"10.1111\/j.1537-2995.2008.01701.x","volume":"48","author":"FB Hollinger","year":"2008","unstructured":"Hollinger FB. Hepatitis B virus infection and transfusion medicine: science and the occult. Transfusion 2008;48:1001\u20131026","journal-title":"Transfusion"},{"issue":"9\u201310","key":"9203_CR27","first-page":"134","volume":"138","author":"C Niederhauser","year":"2008","unstructured":"Niederhauser C, Taleghani BM, Graziani M, Stolz M, Tinguely C, Schneider P. Blood donor screening: how to decrease the risk of transfusion-transmitted hepatitis B virus? Swiss Med Wkly 2008;138(9\u201310):134\u2013141","journal-title":"Swiss Med Wkly"},{"key":"9203_CR28","doi-asserted-by":"crossref","unstructured":"Matsumoto C, Tadokoro K, Fujimura K, Hirakawa S, Mitsunaga S, Juji T. Analysis of HBV infection after blood transfusion in Japan through investigation of a comprehensive donor specimen repository. Transfusion 2001;41:878\u2013884.","DOI":"10.1046\/j.1537-2995.2001.41070878.x"},{"key":"9203_CR29","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1007\/BF02253445","volume":"5","author":"MS Ho","year":"1998","unstructured":"Ho MS, Mau YC, Lu CF, Huang SF, Hsu LC, Lin SR, Hsu HM. Patterns of circulating hepatitis B surface antigen variants among vaccinated children born to hepatitis B surface antigen carrier and non-carrier mothers: a population-based comparative study. J Biomed Sci 1998;5:355\u2013362","journal-title":"J Biomed Sci"},{"key":"9203_CR30","doi-asserted-by":"crossref","first-page":"1027","DOI":"10.1053\/jhep.2001.28708","volume":"34","author":"JL Hou","year":"2001","unstructured":"Hou JL, Wang ZH, Cheng JJ, Lin YL, Lau GKK, Sun J, Zhou FY, Waters J, Karayiannis P, Luo KX. Prevalence of naturally occuring surface gene variants of hepatitis B virus in non-immunized surface antigen-negative Chinese carriers. Hepatology 2001;34:1027\u20131034","journal-title":"Hepatology"},{"key":"9203_CR31","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1002\/jmv.20321","volume":"76","author":"V Thakur","year":"2005","unstructured":"Thakur V, Kazim SN, Guptan RC, Hasnain SE, Bartholomeusz A, Malhotra V, Sarin SK. Transmission of G145R mutant of HBV to an unrelated contact. J Med Virol 2005;76:40\u201346","journal-title":"J Med Virol"},{"key":"9203_CR32","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1016\/0140-6736(90)91874-A","volume":"336","author":"WF Carman","year":"1990","unstructured":"Carman WF, Zanetti AR, Karayiannis P, Waters J, Manzillo G, Tanzi E, Zuckerman AJ, Thomas HC. Vaccine-induced escape mutant of hepatitis B virus. Lancet 1990;336:325\u2013329","journal-title":"Lancet"},{"key":"9203_CR33","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1002\/(SICI)1096-9071(200002)60:2<113::AID-JMV2>3.0.CO;2-0","volume":"60","author":"S Seddigh-Tonekaboni","year":"2000","unstructured":"Seddigh-Tonekaboni S, Waters JA, Jeffers S, Gehrke R, Ofenloch B, Horsch A, Hess G, Thomas HC, Karayiannis P. Effect of variation in the common \u201ca\u201d determinant on the antigenicity of hepatitis B surface antigen. J Med Virol 2000;60:113\u2013121","journal-title":"J Med Virol"},{"key":"9203_CR34","doi-asserted-by":"crossref","first-page":"1382","DOI":"10.1016\/S0140-6736(00)02132-2","volume":"355","author":"AJ Zuckerman","year":"2000","unstructured":"Zuckerman AJ. Effect of hepatitis B virus mutants on efficacy of vaccination. Lancet. 2000;355:1382\u20131383","journal-title":"Lancet"},{"issue":"2","key":"9203_CR35","doi-asserted-by":"crossref","first-page":"613","DOI":"10.1128\/JVI.64.2.613-620.1990","volume":"64","author":"G Radziwill","year":"1990","unstructured":"Radziwill G, Tucker W, Schaller H. Mutational analysis of the hepatitis B virus P gene product: domain structure and RNase H activity. J Virol 1990;64(2):613\u2013620","journal-title":"J Virol"},{"key":"9203_CR36","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1006\/viro.2002.1448","volume":"299","author":"J Torresi","year":"2002","unstructured":"Torresi J, Earnest-Silveira L, Civitico G, Walters TE, Lewin SR, Fyfe J, Locarnini SA, Manns M, Trautwein C, Bock TC. Restoration of replication phenotype of lamivudine-resistant hepatitis B virus mutants by compensatory changes in the \u201cFingers\u201d subdomain of the viral polymerase selected as a consequence of mutations in the overlapping S gene. Virology 2002;299:88\u201399","journal-title":"Virology"}],"container-title":["Hepatology International"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s12072-010-9203-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s12072-010-9203-5\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s12072-010-9203-5","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,6,9]],"date-time":"2020-06-09T21:58:30Z","timestamp":1591739910000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s12072-010-9203-5"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,8,3]]},"references-count":36,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2010,9]]}},"alternative-id":["9203"],"URL":"https:\/\/doi.org\/10.1007\/s12072-010-9203-5","relation":{},"ISSN":["1936-0533","1936-0541"],"issn-type":[{"value":"1936-0533","type":"print"},{"value":"1936-0541","type":"electronic"}],"subject":[],"published":{"date-parts":[[2010,8,3]]}}}