{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,29]],"date-time":"2026-01-29T22:23:51Z","timestamp":1769725431989,"version":"3.49.0"},"reference-count":37,"publisher":"Springer Science and Business Media LLC","issue":"3","license":[{"start":{"date-parts":[[2025,4,3]],"date-time":"2025-04-03T00:00:00Z","timestamp":1743638400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2025,4,3]],"date-time":"2025-04-03T00:00:00Z","timestamp":1743638400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Hepatol Int"],"published-print":{"date-parts":[[2025,6]]},"DOI":"10.1007\/s12072-025-10814-6","type":"journal-article","created":{"date-parts":[[2025,4,5]],"date-time":"2025-04-05T10:02:06Z","timestamp":1743847326000},"page":"633-646","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Model of baseline clinicopathological features predicts non-resolution of drug-induced liver injury at 6\u00a0months"],"prefix":"10.1007","volume":"19","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5801-9458","authenticated-orcid":false,"given":"Chhagan","family":"Bihari","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shvetank","family":"Sharma","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Apoorva","family":"Giri","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Raj Pal","family":"Yadav","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sukriti","family":"Baweja","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Archana","family":"Rastogi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shiv Kumar","family":"Sarin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2025,4,3]]},"reference":[{"issue":"6","key":"10814_CR1","doi-asserted-by":"publisher","first-page":"1222","DOI":"10.1016\/j.jhep.2019.02.014","volume":"70","author":"EASL Clinical Practice Guidelines","year":"2019","unstructured":"EASL Clinical Practice Guidelines. Drug-induced liver injury. J Hepatol. 2019;70(6):1222\u20131261. https:\/\/doi.org\/10.1016\/j.jhep.2019.02.014. Epub 2019 Mar 27 PMID: 30926241","journal-title":"J Hepatol"},{"key":"10814_CR2","doi-asserted-by":"crossref","unstructured":"Bessone F, Robles-Diaz M, Hernandez N, Medina-Caliz I, Lucena MI, Andrade RJ. Assessment of serious acute and chronic idiosyncratic drug-induced liver injury in clinical practice. Sem Liver Dis. 2019;39(03):381\u201394","DOI":"10.1055\/s-0039-1685519"},{"key":"10814_CR3","doi-asserted-by":"publisher","unstructured":"Chalasani N, Fontana RJ, Bonkovsky HL, Watkins PB, Davern T, Serrano J, Yang H, Rochon J, Drug Induced Liver Injury Network (DILIN). Causes, clinical features, and outcomes from a prospective study of drug-induced liver injury in the United States. Gastroenterology. 2008;135(6):1924\u201334, 1934.e1-4. https:\/\/doi.org\/10.1053\/j.gastro.2008.09.011. Epub 2008 Sep 17. PMID: 18955056; PMCID: PMC3654244","DOI":"10.1053\/j.gastro.2008.09.011"},{"key":"10814_CR4","doi-asserted-by":"publisher","unstructured":"Fontana RJ, Hayashi PH, Gu J, Reddy KR, Barnhart H, Watkins PB, Serrano J, Lee WM, Chalasani N, Stolz A, Davern T, Talwakar JA, DILIN Network. Idiosyncratic drug-induced liver injury is associated with substantial morbidity and mortality within 6 months from onset. Gastroenterology. 2014;147(1):96\u2013108.e4. https:\/\/doi.org\/10.1053\/j.gastro.2014.03.045. Epub 2014 Mar 27. PMID: 24681128; PMCID: PMC4285559","DOI":"10.1053\/j.gastro.2014.03.045"},{"key":"10814_CR5","doi-asserted-by":"publisher","unstructured":"Medina-Caliz I, Robles-Diaz M, Garcia-Mu\u00f1oz B, Stephens C, Ortega-Alonso A, Garcia-Cortes M, Gonz\u00e1lez-Jimenez A, Sanabria-Cabrera JA, Moreno I, Fernandez MC, Romero-Gomez M, Navarro JM, Barriocanal AM, Montane E, Hallal H, Blanco S, Soriano G, Roman EM, G\u00f3mez-Dominguez E, Castiella A, Zapata EM, Jimenez-Perez M, Moreno JM, Aldea-Perona A, Hern\u00e1ndez-Guerra M, Prieto M, Zoubek ME, Kaplowitz N, Lucena MI, Andrade RJ, Spanish DILI Registry. Definition and risk factors for chronicity following acute idiosyncratic drug-induced liver injury. J Hepatol. 2016;65(3):532\u201342. https:\/\/doi.org\/10.1016\/j.jhep.2016.05.003. Epub 2016 May 13. PMID: 27184533; PMCID: PMC7458366","DOI":"10.1016\/j.jhep.2016.05.003"},{"issue":"5","key":"10814_CR6","doi-asserted-by":"publisher","first-page":"463","DOI":"10.1002\/jcph.23","volume":"53","author":"A Corsini","year":"2013","unstructured":"Corsini A, Bortolini M. Drug-induced liver injury: the role of drug metabolism and transport. J Clin Pharmacol. 2013;53(5):463\u2013474. https:\/\/doi.org\/10.1002\/jcph.23. Epub 2013 Feb 22 PMID: 23436293","journal-title":"J Clin Pharmacol"},{"issue":"6","key":"10814_CR7","doi-asserted-by":"publisher","first-page":"536","DOI":"10.1016\/j.clinre.2012.06.006","volume":"36","author":"R Kubitz","year":"2012","unstructured":"Kubitz R, Dr\u00f6ge C, Stindt J, Weissenberger K, H\u00e4ussinger D. The bile salt export pump (BSEP) in health and disease. Clin Res Hepatol Gastroenterol. 2012;36(6):536\u2013553. https:\/\/doi.org\/10.1016\/j.clinre.2012.06.006. Epub 2012 Jul 12 PMID: 22795478","journal-title":"Clin Res Hepatol Gastroenterol"},{"key":"10814_CR8","doi-asserted-by":"publisher","unstructured":"de Lima Toccafondo Vieira M, Tagliati CA. Hepatobiliary transporters in drug-induced cholestasis: a perspective on the current identifying tools. Expert Opin Drug Metabolism Toxicol. 2014;10(4):581\u201397. https:\/\/doi.org\/10.1517\/17425255.2014.884069","DOI":"10.1517\/17425255.2014.884069"},{"issue":"1","key":"10814_CR9","doi-asserted-by":"publisher","first-page":"47","DOI":"10.1097\/01.fpc.0000230418.28091.76","volume":"17","author":"C Lang","year":"2007","unstructured":"Lang C, Meier Y, Stieger B, Beuers U, Lang T, Kerb R, et al. Mutations and polymorphisms in the bile salt export pump and the multidrug resistance protein 3 associated with drug-induced liver injury. Pharmacogenet Genomics. 2007;17(1):47\u201360. https:\/\/doi.org\/10.1097\/01.fpc.0000230418.28091.76. PMID: 17264802","journal-title":"Pharmacogenet Genomics"},{"key":"10814_CR10","doi-asserted-by":"publisher","first-page":"55","DOI":"10.2165\/00002018-200932010-00005","volume":"32","author":"RJ Fontana","year":"2009","unstructured":"Fontana RJ, Watkins PB, Bonkovsky HL, Chalasani N, Davern T, Serrano J, et al. Drug-induced liver injury network (DILIN) prospective study: rationale, design and conduct. Drug Saf. 2009;32:55\u201368","journal-title":"Drug Saf"},{"key":"10814_CR11","doi-asserted-by":"publisher","unstructured":"B\u00e9nichou C. Criteria of drug-induced liver disorders. Report of an international consensus meeting. J Hepatol. 1990;11(2):272\u20136. https:\/\/doi.org\/10.1016\/0168-8278(90)90124-a. PMID: 2254635","DOI":"10.1016\/0168-8278(90)90124-a"},{"issue":"6","key":"10814_CR12","doi-asserted-by":"publisher","first-page":"806","DOI":"10.1038\/clpt.2011.58","volume":"89","author":"GP Aithal","year":"2011","unstructured":"Aithal GP, Watkins PB, Andrade RJ, Larrey D, Molokhia M, Takikawa H, et al. Case definition and phenotype standardization in drug-induced liver injury. Clin Pharmacol Ther. 2011;89(6):806\u2013815. https:\/\/doi.org\/10.1038\/clpt.2011.58. Epub 2011 May 4 PMID: 21544079","journal-title":"Clin Pharmacol Ther"},{"issue":"6","key":"10814_CR13","doi-asserted-by":"publisher","first-page":"1581","DOI":"10.1002\/hep.21424","volume":"44","author":"RJ Andrade","year":"2006","unstructured":"Andrade RJ, Lucena MI, Kaplowitz N, Garc\u00eda-Mu\u0146oz B, Borraz Y, Pachkoria K, et al. Outcome of acute idiosyncratic drug-induced liver injury: long-term follow-up in a hepatotoxicity registry. Hepatology. 2006;44(6):1581\u20131588. https:\/\/doi.org\/10.1002\/hep.21424. PMID: 17133470","journal-title":"Hepatology"},{"key":"10814_CR14","unstructured":"https:\/\/cioms.ch\/wp-content\/uploads\/2020\/06\/CIOMS_DILI_Web_16Jun2020.pdf"},{"issue":"1","key":"10814_CR15","doi-asserted-by":"publisher","first-page":"4","DOI":"10.1002\/cld.365.PMID:30992910;PMCID:PMC6448723","volume":"4","author":"JH Lewis","year":"2014","unstructured":"Lewis JH. Causality assessment: which is best expert opinion or RUCAM? Clin Liver Dis (Hoboken). 2014;4(1):4\u20138. https:\/\/doi.org\/10.1002\/cld.365. PMID: 30992910; PMCID: PMC6448723","journal-title":"Clin Liver Dis (Hoboken)"},{"issue":"1","key":"10814_CR16","doi-asserted-by":"publisher","first-page":"25","DOI":"10.1016\/j.jceh.2013.10.005","volume":"4","author":"A Srivastava","year":"2014","unstructured":"Srivastava A. Progressive familial intrahepatic cholestasis. J Clin Exp Hepatol. 2014;4(1):25\u201336. https:\/\/doi.org\/10.1016\/j.jceh.2013.10.005","journal-title":"J Clin Exp Hepatol"},{"issue":"2","key":"10814_CR17","doi-asserted-by":"publisher","first-page":"73","DOI":"10.1055\/s-2008-1040426","volume":"11","author":"JH Hoofnagle","year":"1991","unstructured":"Hoofnagle JH, Di Bisceglie AM. Serologic diagnosis of acute and chronic viral hepatitis. Semin Liver Dis. 1991;11(2):73\u201383. https:\/\/doi.org\/10.1055\/s-2008-1040426. PMID: 1909458","journal-title":"Semin Liver Dis"},{"issue":"5","key":"10814_CR18","doi-asserted-by":"publisher","first-page":"731","DOI":"10.1136\/gut.44.5.731.PMID:10205214;PMCID:PMC1727509","volume":"44","author":"PG Aithal","year":"1999","unstructured":"Aithal PG, Day CP. The natural history of histologically proved drug-induced liver disease. Gut. 1999;44(5):731\u2013735. https:\/\/doi.org\/10.1136\/gut.44.5.731. PMID: 10205214; PMCID: PMC1727509","journal-title":"Gut"},{"issue":"2019","key":"10814_CR19","doi-asserted-by":"publisher","first-page":"8764093","DOI":"10.1155\/2019\/8764093.PMID:31531370;PMCID:PMC6720367","volume":"18","author":"X Li","year":"2019","unstructured":"Li X, Gao P, Niu J. Metabolic comorbidities and risk of development and severity of drug-induced liver injury. Biomed Res Int. 2019;18(2019):8764093. https:\/\/doi.org\/10.1155\/2019\/8764093. PMID: 31531370; PMCID: PMC6720367","journal-title":"Biomed Res Int"},{"key":"10814_CR20","doi-asserted-by":"publisher","first-page":"100","DOI":"10.1002\/ygh2.445","volume":"3","author":"AN Shashidhara","year":"2021","unstructured":"Shashidhara AN, Patil A, Bihari C. Co-existing non-transfusion-dependent hemoglobinopathies cause greater clinical and pathological severity of the chronic liver disease. GastroHep. 2021;3:100\u2013106. https:\/\/doi.org\/10.1002\/ygh2.445","journal-title":"GastroHep"},{"issue":"6","key":"10814_CR21","doi-asserted-by":"publisher","first-page":"138","DOI":"10.3389\/fcell.2018.00138","volume":"31","author":"NCW Lee","year":"2018","unstructured":"Lee NCW, Carella MA, Papa S, Bubici C. High expression of glycolytic genes in cirrhosis correlates with the risk of developing liver cancer. Front Cell Dev Biol. 2018;31(6):138. https:\/\/doi.org\/10.3389\/fcell.2018.00138. PMID: 30430110; PMCID: PMC6220322","journal-title":"Front Cell Dev Biol"},{"issue":"12","key":"10814_CR22","doi-asserted-by":"publisher","DOI":"10.3389\/fphar.2021.627133","volume":"8","author":"Q Wang","year":"2021","unstructured":"Wang Q, Huang A, Wang JB, Zou Z. Chronic drug-induced liver injury: updates and future challenges. Front Pharmacol. 2021;8(12): 627133. https:\/\/doi.org\/10.3389\/fphar.2021.627133. PMID: 33762948; PMCID: PMC7982586","journal-title":"Front Pharmacol"},{"key":"10814_CR23","doi-asserted-by":"publisher","unstructured":"Andrade RJ, Aithal GP, de Boer YS, Liberal R, Gerbes A, Regev A, Terziroli Beretta-Piccoli B, Schramm C, Kleiner DE, De Martin E, Kullak-Ublick GA, Stirnimann G, Devarbhavi H, Vierling JM, Manns MP, Sebode M, Londo\u00f1o MC, Avigan M, Robles-Diaz M, Garc\u00eda-Cortes M, Atallah E, Heneghan M, Chalasani N, Trivedi PJ, Hayashi PH, Taubert R, Fontana RJ, Weber S, Oo YH, Zen Y, Licata A, Lucena MI, Mieli-Vergani G, Vergani D, Bj\u00f6rnsson ES, IAIHG and EASL DHILI Consortium. Nomenclature, diagnosis, and management of drug-induced autoimmune-like hepatitis (DI-ALH): an expert opinion meeting report. J Hepatol. 2023;79(3):853\u201366. https:\/\/doi.org\/10.1016\/j.jhep.2023.04.033. Epub 2023 May 8. PMID: 37164270; PMCID: PMC10735171","DOI":"10.1016\/j.jhep.2023.04.033"},{"issue":"5","key":"10814_CR24","doi-asserted-by":"publisher","first-page":"651","DOI":"10.1517\/17425255.2.5.651","volume":"2","author":"I Ieiri","year":"2006","unstructured":"Ieiri I, Takane H, Hirota T, Otsubo K, Higuchi S. Genetic polymorphisms of drug transporters: pharmacokinetic and pharmacodynamic consequences in pharmacotherapy. Expert Opin Drug Metab Toxicol. 2006;2(5):651\u201374","journal-title":"Expert Opin Drug Metab Toxicol"},{"issue":"8","key":"10814_CR25","doi-asserted-by":"publisher","first-page":"808","DOI":"10.1007\/s00535-015-1148-y","volume":"51","author":"K Okushin","year":"2016","unstructured":"Okushin K, Tsutsumi T, Enooku K, et al. The intrahepatic expression levels of bile acid transporters are inversely correlated with the histological progression of nonalcoholic fatty liver disease. J Gastroenterol. 2016;51(8):808\u201318","journal-title":"J Gastroenterol"},{"issue":"9","key":"10814_CR26","doi-asserted-by":"publisher","first-page":"2282","DOI":"10.1016\/j.xphs.2017.04.053","volume":"106","author":"N Thakkar","year":"2017","unstructured":"Thakkar N, Slizgi JR, Brouwer KLR. Effect of liver disease on hepatic transporter expression and function. J Pharm Sci. 2017;106(9):2282\u201394. https:\/\/doi.org\/10.1016\/j.xphs.2017.04.053","journal-title":"J Pharm Sci"},{"key":"10814_CR27","doi-asserted-by":"publisher","first-page":"8","DOI":"10.3389\/fphar.2012.00008","volume":"3","author":"H Christensen","year":"2012","unstructured":"Christensen H, Hermann M. Immunological response as a source to variability in drug metabolism and transport. Front Pharmacol. 2012;3:8. https:\/\/doi.org\/10.3389\/fphar.2012.00008","journal-title":"Front Pharmacol"},{"issue":"4","key":"10814_CR28","doi-asserted-by":"publisher","first-page":"667","DOI":"10.1007\/s00428-018-2330-4","volume":"472","author":"SM Shasthry","year":"2018","unstructured":"Shasthry SM, Rastogi A, Bihari C, Vijayaraghavan R, Arora V, Sharma MK, et al. Histological activity score on baseline liver biopsy can predict non-response to steroids in patients with severe alcoholic hepatitis. Virchows Arch. 2018;472(4):667\u201375. https:\/\/doi.org\/10.1007\/s00428-018-2330-4. Epub 2018 Mar 7 PMID: 29516163","journal-title":"Virchows Arch"},{"issue":"5","key":"10814_CR29","doi-asserted-by":"publisher","first-page":"577","DOI":"10.1080\/00365521.2024.2309527","volume":"59","author":"AGC Broekhoven","year":"2024","unstructured":"Broekhoven AGC, Ostyn T, van Melkebeke L, Verspaget HW, van der Merwe S, Verbeek J, et al. Histological characteristics in patients admitted to the hospital with alcoholic hepatitis complicated by acute-on-chronic liver failure. Scand J Gastroenterol. 2024;59(5):577\u2013583. https:\/\/doi.org\/10.1080\/00365521.2024.2309527. Epub 2024 Feb 2 PMID: 38306114","journal-title":"Scand J Gastroenterol"},{"key":"10814_CR30","doi-asserted-by":"publisher","unstructured":"Lucena MI, Andrade RJ, Kaplowitz N, Garc\u00eda-Cortes M, Fern\u00e1ndez MC, Romero-Gomez M, Bruguera M, Hallal H, Robles-Diaz M, Rodriguez-Gonz\u00e1lez JF, Navarro JM, Salmeron J, Martinez-Odriozola P, P\u00e9rez-Alvarez R, Borraz Y, Hidalgo R, Spanish Group for the Study of Drug-Induced Liver Disease. Phenotypic characterization of idiosyncratic drug-induced liver injury: the influence of age and sex. Hepatology. 2009;49(6):2001\u20139. https:\/\/doi.org\/10.1002\/hep.22895. PMID: 19475693","DOI":"10.1002\/hep.22895"},{"key":"10814_CR31","doi-asserted-by":"publisher","unstructured":"Bj\u00f6rnsson ES. Epidemiology, predisposing factors, and outcomes of drug-induced liver injury. Clin Liver Dis 2020;24:1\u201310. https:\/\/doi.org\/10.1016\/j.cld.2019.08.002","DOI":"10.1016\/j.cld.2019.08.002"},{"issue":"6","key":"10814_CR32","doi-asserted-by":"publisher","first-page":"1373","DOI":"10.1002\/hep.32283","volume":"75","author":"CY Wang","year":"2022","unstructured":"Wang CY, Deng Y, Li P, Zheng S, Chen G, Zhou G, et al. Prediction of biochemical nonresolution in patients with chronic drug-induced liver injury: a large multicenter study. Hepatology. 2022;75(6):1373\u20131385. https:\/\/doi.org\/10.1002\/hep.32283. Epub 2022 Jan 6 PMID: 34919746","journal-title":"Hepatology"},{"key":"10814_CR33","doi-asserted-by":"crossref","unstructured":"Ganie SM, Pramanik PKD. A comparative analysis of boosting algorithms for chronic liver disease prediction. Healthcare Analy. 2024;5:100313. ISSN 2772-4425","DOI":"10.1016\/j.health.2024.100313"},{"key":"10814_CR34","doi-asserted-by":"publisher","first-page":"8589","DOI":"10.1038\/s41598-024-59183-4","volume":"14","author":"B Njei","year":"2024","unstructured":"Njei B, Osta E, Njei N, et al. An explainable machine learning model for prediction of high-risk nonalcoholic steatohepatitis. Sci Rep. 2024;14:8589. https:\/\/doi.org\/10.1038\/s41598-024-59183-4","journal-title":"Sci Rep"},{"key":"10814_CR35","doi-asserted-by":"publisher","first-page":"6968","DOI":"10.1038\/s41598-021-86327-7","volume":"11","author":"A Moncada-Torres","year":"2021","unstructured":"Moncada-Torres A, van Maaren MC, Hendriks MP, et al. Explainable machine learning can outperform Cox regression predictions and provide insights into breast cancer survival. Sci Rep. 2021;11:6968. https:\/\/doi.org\/10.1038\/s41598-021-86327-7","journal-title":"Sci Rep"},{"key":"10814_CR36","doi-asserted-by":"publisher","first-page":"12","DOI":"10.1016\/j.jclinepi.2019.02.004","volume":"110","author":"E Christodoulou","year":"2019","unstructured":"Christodoulou E, Ma J, Collins GS, Steyerberg EW, Verbakel JY, Van Calster B. A systematic review shows no performance benefit of machine learning over logistic regression for clinical prediction models. J Clin Epidemiol. 2019;110:12\u201322. https:\/\/doi.org\/10.1016\/j.jclinepi.2019.02.004. (Epub 2019 Feb 11 PMID: 30763612)","journal-title":"J Clin Epidemiol"},{"key":"10814_CR37","doi-asserted-by":"publisher","DOI":"10.1016\/j.prp.2021.153451","volume":"221","author":"M Fassan","year":"2021","unstructured":"Fassan M, Mescoli C, Sbaraglia M, Guzzardo V, Russo FP, Fabris R, et al. Liver histopathology in COVID-19 patients: a mono-institutional series of liver biopsies and autopsy specimens. Pathol Res Pract. 2021;221: 153451","journal-title":"Pathol Res Pract"}],"container-title":["Hepatology International"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12072-025-10814-6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s12072-025-10814-6\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12072-025-10814-6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,6,4]],"date-time":"2025-06-04T16:29:52Z","timestamp":1749054592000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s12072-025-10814-6"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,4,3]]},"references-count":37,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2025,6]]}},"alternative-id":["10814"],"URL":"https:\/\/doi.org\/10.1007\/s12072-025-10814-6","relation":{},"ISSN":["1936-0533","1936-0541"],"issn-type":[{"value":"1936-0533","type":"print"},{"value":"1936-0541","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,4,3]]},"assertion":[{"value":"11 December 2024","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"28 February 2025","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"3 April 2025","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"None.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"All procedures performed in studies involving human participants were following the ethical standards of the institutional and national research committee and with the 1964 Helsinki Declaration and its later amendments or comparable ethical standards (and\/or in case humans were involved). Institutional Ethics Committee Institute of Liver and Biliary Sciences, New Delhi, India, waived the informed consent and approved the study vide- IEC\/2021\/86\/MA12.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}}]}}