{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,17]],"date-time":"2026-09-17T03:21:07Z","timestamp":1789615267165,"version":"build-2803163510"},"reference-count":6,"publisher":"Springer Science and Business Media LLC","issue":"3","license":[{"start":{"date-parts":[[2026,5,13]],"date-time":"2026-05-13T00:00:00Z","timestamp":1778630400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2026,5,13]],"date-time":"2026-05-13T00:00:00Z","timestamp":1778630400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"DOI":"10.13039\/501100001774","name":"The University of Sydney","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100001774","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Hepatol Int"],"published-print":{"date-parts":[[2026,6]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Artificial intelligence (AI) and digital pathology have the potential to augment liver biopsy interpretation in MAFLD in clinical practice and trials assessment. However, attitudes and barriers to its implementation have not been systematically explored.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A survey focusing on conventional liver histology, digital pathology and its AI applications in MAFLD\/MASH was conducted among hepatologists and liver pathologists in the Asia Pacific region.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>AI-assisted digital pathology is perceived to be a valuable addition to existing histological reporting in MAFLD\/MASH. Defined standards for application and validation of AI models are important priorities for their implementation.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>There is consensus among clinical experts in the Asia Pacific that AI-assisted histological assessment is useful in MAFLD\/MASH interpretation. However, there remain important challenges to the adoption of these technologies into routine clinical workflows.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1007\/s12072-026-11092-6","type":"journal-article","created":{"date-parts":[[2026,5,13]],"date-time":"2026-05-13T16:11:11Z","timestamp":1778688671000},"page":"539-549","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["The Asian Pacific Association of the Study of the Liver expert survey on artificial intelligence-assisted reporting of liver histopathology in metabolic dysfunction associated fatty liver disease"],"prefix":"10.1007","volume":"20","author":[{"given":"H.","family":"Elangovan","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K.","family":"Akbary","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Rastogi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Wee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G.","family":"Soon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L.","family":"Adams","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E.","family":"Carr-Boyd","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Clouston","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C. 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KA is an employee of Histoindex. YYD has research collaborations with funding from Histoindex. WKC has served as a consultant or advisory board member for Abbott, Abbvie, Boehringer Ingelheim, IPSEN, Kowa, Novo Nordisk, Roche, and Zuellig Pharma; as a speaker for Abbott, Echosens, Hisky Medical, Novo Nordisk, Roche and Viatris; and has received research grants from Abbott and Roche. YY has served as a consultant for Zydus and an adviser for Novo Nordisk. GS received a fee-for-service from Clinnovate Health. MLY receives research support from Abbvie, Abbott Diagnostic, BMS, Gilead, Merck, Novo Nordisc and Roche diagnostics, serves as a consultant of Abbvie, Abbott Diagnostic, BMS, Gilead, Novo Nordisc, Roche and Roche diagnostics, and serves as a speaker of Abbvie, BMS, Eisai, Gilead, Roche and Roche diagnostics. TK received lecture fees from ASKA Pharmaceutical Co., Ltd., Taisho Pharmaceutical Co., Ltd., Kowa Company, Ltd., AbbVie GK., Eisai Co., Ltd., EA Pharma Co., Ltd., Nippon Boehringer Ingelheim Co., Ltd., Sumitomo Pharma Co., Ltd., Novo Nordisk Pharma Ltd., Otsuka Pharmaceutical Co., Ltd., Janssen Pharmaceutical K.K. AW has received a fee-for-service from Histoindex. SUK has served as an advisory committee member of Gilead Sciences, Bayer, Eisai and Novo Nordisk. He is a speaker for Gilead Sciences, GSK, Bayer, Eisai, Abbive, EchoSens, MSD, Eisai, Otsuka and Bristol-Myers Squibb. He has also received a research grant from Abbive and Bristol-Myers Squibb. SUK is an Editorial Board member of Clinical and Molecular Hepatology, Gut and Liver, Journal of Gastroenterology and Hepatology, and Clinical Gastroenterology and Hepatology. YT has received research funding and honoraria from AbbVie GK, Otsuka Pharmaceutical Co., Ltd., Gilead, G AstraZeneca, ASKA Pharmaceutical Co., Ltd, GSK, Eisai and Chugai Pharmaceutical Co., Ltd. MHZ serves as a speaker for AstraZeneca, Hisky Medical Technologies, and Novo Nordisk; as a consultant for Boehringer Ingelheim and Eieling Technology; and has received consulting fees from Boehringer Ingelheim.","order":1,"name":"Ethics","label":"Conflict of interest","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"This survey was conducted in accordance with the European Pharmaceutical Market Research Association (EphMRA) code of ethics.","order":2,"name":"Ethics","label":"Ethical statement","group":{"name":"EthicsHeading","label":"Declarations"}}]}}