{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,16]],"date-time":"2026-06-16T16:31:46Z","timestamp":1781627506515,"version":"3.54.5"},"reference-count":24,"publisher":"Springer Science and Business Media LLC","issue":"7","license":[{"start":{"date-parts":[[2015,3,17]],"date-time":"2015-03-17T00:00:00Z","timestamp":1426550400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Clin Transl Oncol"],"published-print":{"date-parts":[[2015,7]]},"DOI":"10.1007\/s12094-015-1278-y","type":"journal-article","created":{"date-parts":[[2015,3,16]],"date-time":"2015-03-16T11:19:05Z","timestamp":1426504745000},"page":"557-563","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":22,"title":["Correlation between down-expression of miR-431 and clinicopathological significance in HCC tissues"],"prefix":"10.1007","volume":"17","author":[{"given":"L.","family":"Pan","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"F.","family":"Ren","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Rong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Y.","family":"Dang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Y.","family":"Luo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D.","family":"Luo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G.","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2015,3,17]]},"reference":[{"key":"1278_CR1","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1016\/j.curtheres.2014.04.001","volume":"76","author":"Q Hu","year":"2014","unstructured":"Hu Q, Lou GG, Liu YC, Qian L, Lv BD. The tumor necrosis factor-alpha-308 and -238 polymorphisms and risk of hepatocellular carcinoma for Asian populations: a meta-analysis. Curr Ther Res Clin Exp. 2014;76:70\u20135.","journal-title":"Curr Ther Res Clin Exp"},{"key":"1278_CR2","doi-asserted-by":"crossref","first-page":"1969","DOI":"10.1038\/onc.2010.594","volume":"30","author":"DR McGivern","year":"2011","unstructured":"McGivern DR, Lemon SM. Virus-specific mechanisms of carcinogenesis in hepatitis C virus associated liver cancer. Oncogene. 2011;30:1969\u201383.","journal-title":"Oncogene"},{"issue":"Suppl 4","key":"1278_CR3","first-page":"34","volume":"15","author":"SL Ye","year":"2010","unstructured":"Ye SL, Takayama T, Geschwind J, Marrero JA, Bronowicki JP. Current approaches to the treatment of early hepatocellular carcinoma. Oncologist. 2010;15(Suppl 4):34\u201341.","journal-title":"Oncologist"},{"key":"1278_CR4","doi-asserted-by":"crossref","first-page":"486","DOI":"10.1053\/j.seminoncol.2012.05.005","volume":"39","author":"S Tanaka","year":"2012","unstructured":"Tanaka S, Arii S. Molecular targeted therapies in hepatocellular carcinoma. Semin Oncol. 2012;39:486\u201392.","journal-title":"Semin Oncol"},{"key":"1278_CR5","doi-asserted-by":"crossref","first-page":"593","DOI":"10.3892\/mco.2013.119","volume":"1","author":"YJ Zhao","year":"2013","unstructured":"Zhao YJ, Ju Q, Li GC. Tumor markers for hepatocellular carcinoma. Mol Clin Oncol. 2013;1:593\u20138.","journal-title":"Mol Clin Oncol"},{"key":"1278_CR6","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1016\/S0092-8674(04)00045-5","volume":"116","author":"DP Bartel","year":"2004","unstructured":"Bartel DP. MicroRNAs: genomics, biogenesis, mechanism, and function. Cell. 2004;116:281\u201397.","journal-title":"Cell"},{"key":"1278_CR7","doi-asserted-by":"crossref","first-page":"522","DOI":"10.1038\/nrg1379","volume":"5","author":"L He","year":"2004","unstructured":"He L, Hannon GJ. MicroRNAs: small RNAs with a big role in gene regulation. Nat Rev Genet. 2004;5:522\u201331.","journal-title":"Nat Rev Genet"},{"key":"1278_CR8","doi-asserted-by":"crossref","first-page":"834","DOI":"10.1038\/nature03702","volume":"435","author":"J Lu","year":"2005","unstructured":"Lu J, Getz G, Miska EA, Alvarez-Saavedra E, Lamb J, Peck D, et al. MicroRNA expression profiles classify human cancers. Nature. 2005;435:834\u20138.","journal-title":"Nature"},{"key":"1278_CR9","doi-asserted-by":"crossref","first-page":"896","DOI":"10.1038\/nature06783","volume":"452","author":"J Elmen","year":"2008","unstructured":"Elmen J, Lindow M, Schutz S, Lawrence M, Petri A, Obad S, et al. LNA-mediated microRNA silencing in non-human primates. Nature. 2008;452:896\u20139.","journal-title":"Nature"},{"key":"1278_CR10","doi-asserted-by":"crossref","first-page":"685","DOI":"10.1038\/nature04303","volume":"438","author":"J Krutzfeldt","year":"2005","unstructured":"Krutzfeldt J, Rajewsky N, Braich R, Rajeev KG, Tuschl T, Manoharan M, et al. Silencing of microRNAs in vivo with \u2018antagomirs\u2019. Nature. 2005;438:685\u20139.","journal-title":"Nature"},{"key":"1278_CR11","doi-asserted-by":"crossref","first-page":"7608","DOI":"10.1158\/0008-5472.CAN-11-1144","volume":"71","author":"JK Park","year":"2011","unstructured":"Park JK, Kogure T, Nuovo GJ, Jiang J, He L, Kim JH, et al. miR-221 silencing blocks hepatocellular carcinoma and promotes survival. Cancer Res. 2011;71:7608\u201316.","journal-title":"Cancer Res"},{"key":"1278_CR12","doi-asserted-by":"crossref","first-page":"1470","DOI":"10.3892\/ijo.2011.1274","volume":"40","author":"T Tanaka","year":"2012","unstructured":"Tanaka T, Sugaya S, Kita K, Arai M, Kanda T, Fujii K, et al. Inhibition of cell viability by human IFN-beta is mediated by microRNA-431. Int J Oncol. 2012;40:1470\u20136.","journal-title":"Int J Oncol"},{"key":"1278_CR13","doi-asserted-by":"crossref","first-page":"907","DOI":"10.1096\/fj.12-220905","volume":"27","author":"L Fang","year":"2013","unstructured":"Fang L, Du WW, Yang X, Chen K, Ghanekar A, Levy G, et al. Versican 3\u2032-untranslated region (3\u2032-UTR) functions as a ceRNA in inducing the development of hepatocellular carcinoma by regulating miRNA activity. FASEB J. 2013;27:907\u201319.","journal-title":"FASEB J"},{"key":"1278_CR14","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1186\/1741-7015-10-28","volume":"10","author":"G Chen","year":"2012","unstructured":"Chen G, Kronenberger P, Teugels E, Umelo IA, De Greve J. Targeting the epidermal growth factor receptor in non-small cell lung cancer cells: the effect of combining RNA interference with tyrosine kinase inhibitors or cetuximab. BMC Med. 2012;10:28.","journal-title":"BMC Med"},{"key":"1278_CR15","doi-asserted-by":"crossref","first-page":"e61054","DOI":"10.1371\/journal.pone.0061054","volume":"8","author":"Y Dang","year":"2013","unstructured":"Dang Y, Luo D, Rong M, Chen G. Underexpression of miR-34a in hepatocellular carcinoma and its contribution towards enhancement of proliferating inhibitory effects of agents targeting c-MET. PLoS One. 2013;8:e61054.","journal-title":"PLoS One"},{"key":"1278_CR16","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1186\/1471-2407-13-21","volume":"13","author":"M Rong","year":"2013","unstructured":"Rong M, Chen G, Dang Y. Increased miR-221 expression in hepatocellular carcinoma tissues and its role in enhancing cell growth and inhibiting apoptosis in vitro. BMC Cancer. 2013;13:21.","journal-title":"BMC Cancer"},{"key":"1278_CR17","doi-asserted-by":"crossref","first-page":"e60317","DOI":"10.1371\/journal.pone.0060317","volume":"8","author":"G Chen","year":"2013","unstructured":"Chen G, Umelo IA, Lv S, Teugels E, Fostier K, Kronenberger P, et al. miR-146a inhibits cell growth, cell migration and induces apoptosis in non-small cell lung cancer cells. PLoS One. 2013;8:e60317.","journal-title":"PLoS One"},{"key":"1278_CR18","doi-asserted-by":"crossref","first-page":"2195","DOI":"10.1016\/j.febslet.2006.03.019","volume":"580","author":"G Wheeler","year":"2006","unstructured":"Wheeler G, Ntounia-Fousara S, Granda B, Rathjen T, Dalmay T. Identification of new central nervous system specific mouse microRNAs. FEBS Lett. 2006;580:2195\u2013200.","journal-title":"FEBS Lett"},{"key":"1278_CR19","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1007\/s10048-008-0133-5","volume":"9","author":"K Abu-Elneel","year":"2008","unstructured":"Abu-Elneel K, Liu T, Gazzaniga FS, Nishimura Y, Wall DP, Geschwind DH, et al. Heterogeneous dysregulation of microRNAs across the autism spectrum. Neurogenetics. 2008;9:153\u201361.","journal-title":"Neurogenetics"},{"key":"1278_CR20","doi-asserted-by":"crossref","first-page":"670621","DOI":"10.1155\/2013\/670621","volume":"2013","author":"AM Salem","year":"2013","unstructured":"Salem AM, Ismail S, Zarouk WA, Abdul Baky O, Sayed AA, Abd El-Hamid S, et al. Genetic variants of neurotransmitter-related genes and miRNAs in Egyptian autistic patients. Sci World J. 2013;2013:670621.","journal-title":"Sci World J"},{"key":"1278_CR21","first-page":"35","volume":"6","author":"D Wu","year":"2013","unstructured":"Wu D, Murashov AK. MicroRNA-431 regulates axon regeneration in mature sensory neurons by targeting the Wnt antagonist Kremen1. Front Mol Neurosci. 2013;6:35.","journal-title":"Front Mol Neurosci"},{"key":"1278_CR22","doi-asserted-by":"crossref","first-page":"E968","DOI":"10.1210\/jc.2011-2982","volume":"97","author":"R Liu","year":"2012","unstructured":"Liu R, Ma X, Xu L, Wang D, Jiang X, Zhu W, et al. Differential microRNA expression in peripheral blood mononuclear cells from Graves\u2019 disease patients. J Clin Endocrinol Metab. 2012;97:E968\u201372.","journal-title":"J Clin Endocrinol Metab"},{"key":"1278_CR23","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1016\/j.bbrc.2014.10.008","volume":"454","author":"MJ Wu","year":"2014","unstructured":"Wu MJ, Ke PY, Horng JT. RacGTPase-activating protein 1 interacts with hepatitis C virus polymerase NS5B to regulate viral replication. Biochem Biophys Res Commun. 2014;454:19\u201324.","journal-title":"Biochem Biophys Res Commun"},{"key":"1278_CR24","doi-asserted-by":"crossref","first-page":"3893","DOI":"10.1128\/JVI.69.6.3893-3896.1995","volume":"69","author":"D Sakamuro","year":"1995","unstructured":"Sakamuro D, Furukawa T, Takegami T. Hepatitis C virus nonstructural protein NS3 transforms NIH 3T3 cells. J Virol. 1995;69:3893\u20136.","journal-title":"J Virol"}],"container-title":["Clinical and Translational Oncology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s12094-015-1278-y.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s12094-015-1278-y\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s12094-015-1278-y","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,8,30]],"date-time":"2020-08-30T22:27:07Z","timestamp":1598826427000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s12094-015-1278-y"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,3,17]]},"references-count":24,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2015,7]]}},"alternative-id":["1278"],"URL":"https:\/\/doi.org\/10.1007\/s12094-015-1278-y","relation":{},"ISSN":["1699-048X","1699-3055"],"issn-type":[{"value":"1699-048X","type":"print"},{"value":"1699-3055","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,3,17]]}}}