{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,16]],"date-time":"2026-04-16T11:00:31Z","timestamp":1776337231048,"version":"3.51.2"},"reference-count":27,"publisher":"Springer Science and Business Media LLC","issue":"11","license":[{"start":{"date-parts":[[2017,8,10]],"date-time":"2017-08-10T00:00:00Z","timestamp":1502323200000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Clin Transl Oncol"],"published-print":{"date-parts":[[2017,11]]},"DOI":"10.1007\/s12094-017-1728-9","type":"journal-article","created":{"date-parts":[[2017,8,10]],"date-time":"2017-08-10T04:54:19Z","timestamp":1502340859000},"page":"1388-1392","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Cytoreductive surgery and hyperthermic intraperitoneal chemotherapy for pseudomyxoma peritonei and appendix tumours in elderly patients: Is it justified?"],"prefix":"10.1007","volume":"19","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1718-3352","authenticated-orcid":false,"given":"V.","family":"L\u00f3pez-L\u00f3pez","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P. A.","family":"Cascales-Campos","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E.","family":"Gil","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.","family":"Arevalo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Gonzalez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.","family":"Gil","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F. C.","family":"Mu\u00f1oz-Casares","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J. T.","family":"Melero","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P.","family":"Barrios","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R.","family":"Morales","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"I.","family":"Ramos","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G.","family":"Ortega","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"B.","family":"Camps","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L.","family":"Gonz\u00e1lez-Bay\u00f3n","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P.","family":"Bretcha-Boix","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.","family":"Farr\u00e9-Alegre","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.","family":"Gonz\u00e1lez-Moreno","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P.","family":"Parrilla","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2017,8,10]]},"reference":[{"key":"1728_CR1","unstructured":"National Institute for Health and Clinical Excellence (NICE), Complete cytoreduction for pseudomyxoma peritonei (SugarbakerTechnique). 2004. \n                        http:\/\/www.nice.org.uk\/Guidance\/IPG56.\n                        \n                     Accessed 1 April 2010"},{"key":"1728_CR2","doi-asserted-by":"crossref","first-page":"727","DOI":"10.1007\/s10434-999-0727-7","volume":"6","author":"PH Sugarbaker","year":"1999","unstructured":"Sugarbaker PH, Chang D. Results of treatment of 385 patients with peritoneal surface spread of appendiceal malignancy. Ann Surg Oncol. 1999;6:727\u201331.","journal-title":"Ann Surg Oncol"},{"key":"1728_CR3","doi-asserted-by":"crossref","first-page":"300","DOI":"10.1097\/01.sla.0000152015.76731.1f","volume":"241","author":"TJ Miner","year":"2005","unstructured":"Miner TJ, Shia J, Jaques DP, Klimstra DS, Brennan MF, Coit DG. Long-term survival following treatment of pseudomixoma peritonei: an analysis of surgical therapy. Ann Surg. 2005;241:300\u20138.","journal-title":"Ann Surg"},{"key":"1728_CR4","first-page":"407","volume":"27","author":"D Elias","year":"2003","unstructured":"Elias D, Laurent S, Antoun S, et al. Pseudomyxoma peritonei treated with complete resection and immediate intraperitoneal chemotherapy [in French]. Gastroenterol Clin Biol. 2003;27:407\u201312.","journal-title":"Gastroenterol Clin Biol"},{"key":"1728_CR5","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1245\/ASO.2004.07.002","volume":"11","author":"M Deraco","year":"2004","unstructured":"Deraco M, Baratti D, Inglese MG, et al. Peritonectomy and intraperitoneal hyperthermic perfusion (IPHP): a strategy that has confirmed its efficacy in patients with pseudomyxoma peritonei. Ann Surg Oncol. 2004;11:393\u20138.","journal-title":"Ann Surg Oncol"},{"key":"1728_CR6","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1007\/s00384-004-0648-7","volume":"20","author":"Z G\u00fcner","year":"2005","unstructured":"G\u00fcner Z, Schmidt U, Dahlke MH, Schlitt HJ, Klempnauer J, Piso P. Cytoreductive surgery and intraperitoneal chemotherapy for pseudomyxoma peritonei. Int J Colorectal Dis. 2005;20:155\u201360.","journal-title":"Int J Colorectal Dis"},{"key":"1728_CR7","doi-asserted-by":"crossref","first-page":"551","DOI":"10.1097\/01.pas.0000202039.74837.7d","volume":"30","author":"RF Bradley","year":"2006","unstructured":"Bradley RF, Stewart JH IV, Russell GB, et al. Pseudomyxoma peritonei of appendiceal origin: a clinicopathologic analysis of 101 patients uniformly treated at a single institution, with literature review. Am J Surg Pathol. 2006;30:551\u20139.","journal-title":"Am J Surg Pathol"},{"key":"1728_CR8","doi-asserted-by":"crossref","first-page":"2449","DOI":"10.1200\/JCO.2011.39.7166","volume":"30","author":"TC Chua","year":"2012","unstructured":"Chua TC, Moran BJ, Sugarbaker PH, et al. Early- and long-term outcome data of patients with pseudomyxoma peritonei from appendiceal origin treated by a strategy of cytoreductive surgery and hyperthermic intraperitoneal chemotherapy. J Clin Oncol. 2012;30:2449\u201356.","journal-title":"J Clin Oncol"},{"key":"1728_CR9","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1007\/s12094-015-1413-9","volume":"18","author":"P Barrios","year":"2016","unstructured":"Barrios P, Losa F, Gonzalez-Moreno S, et al. Recommendations in the management of epithelial appendiceal neoplasms and peritoneal dissemination from mucinous tumours (pseudomyxoma peritonei). Clin Transl Oncol. 2016;18:437\u201348.","journal-title":"Clin Transl Oncol"},{"key":"1728_CR10","doi-asserted-by":"crossref","first-page":"865","DOI":"10.1016\/j.jamcollsurg.2006.08.026","volume":"203","author":"FE Turrentine","year":"2006","unstructured":"Turrentine FE, Wang H, Simpson VB, Jones RS. Surgical risk factors, morbidity, and mortality in elderly patients. J Am Coll Surg. 2006;203:865\u201377.","journal-title":"J Am Coll Surg"},{"key":"1728_CR11","doi-asserted-by":"crossref","first-page":"426","DOI":"10.1097\/00000658-199522240-00002","volume":"222","author":"Y Fong","year":"1995","unstructured":"Fong Y, Blumbart LH, Fortner JG, Brennan MF. Pancreatic or liver resection for malignancy is safe and effective for the elderly. Ann Surg. 1995;222:426\u201334.","journal-title":"Ann Surg"},{"key":"1728_CR12","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1002\/jso.10160","volume":"81","author":"SL Saltzstein","year":"2002","unstructured":"Saltzstein SL, Behling CA. 5\u201310\u00a0year survival in cancer patients aged 90 and older: a study of 37318 patients from SEER. J Surg Oncol. 2002;81:113\u20136.","journal-title":"J Surg Oncol"},{"key":"1728_CR13","doi-asserted-by":"crossref","first-page":"614","DOI":"10.1016\/j.ejso.2006.03.005","volume":"32","author":"BJ Moran","year":"2006","unstructured":"Moran BJ. Establishment of a peritoneal malignancy treatment centre in the United Kingdom. Eur J Surg Oncol. 2006;32:614\u20138.","journal-title":"Eur J Surg Oncol"},{"key":"1728_CR14","doi-asserted-by":"crossref","first-page":"5317","DOI":"10.3748\/wjg.v18.i38.5317","volume":"18","author":"I K\u00f6nigsrainer","year":"2012","unstructured":"K\u00f6nigsrainer I, Beckert S. Cytoreductive surgery and hyperthermic intraperitoneal chemotherapy: where are we? World J Gastroenterol. 2012;18:5317\u201320.","journal-title":"World J Gastroenterol"},{"key":"1728_CR15","doi-asserted-by":"crossref","first-page":"348","DOI":"10.1097\/SLA.0b013e3182436c28","volume":"255","author":"S Kusamura","year":"2012","unstructured":"Kusamura S, Baratti D, Deraco M. Multidimensional analysis of the learning curve for cytoreductive surgery and hyperthermic intraperitoneal chemotherapy in peritoneal surface malignancies. Ann Surg. 2012;255:348\u201356.","journal-title":"Ann Surg"},{"key":"1728_CR16","doi-asserted-by":"crossref","first-page":"36","DOI":"10.4251\/wjgo.v2.i1.36","volume":"2","author":"D Baratti","year":"2010","unstructured":"Baratti D, Kusamura S, Laterza B, et al. Early and long-term postoperative management following cytoreductive surgery and hyperthermic intraperitoneal chemotherapy. World J Gastrointest Oncol. 2010;2:36\u201343.","journal-title":"World J Gastrointest Oncol"},{"key":"1728_CR17","first-page":"5689","volume":"34","author":"A Macr\u00ec","year":"2014","unstructured":"Macr\u00ec A, Arcoraci V, Belgrano V, et al. Short-term outcome of cytoreductive surgery and hyperthermic intraperitoneal chemotherapy: preliminary analysis of a multicentre study. Anticancer Res. 2014;34:5689\u201393.","journal-title":"Anticancer Res"},{"key":"1728_CR18","doi-asserted-by":"crossref","first-page":"184","DOI":"10.1016\/j.suronc.2013.06.001","volume":"22","author":"P Tabrizian","year":"2013","unstructured":"Tabrizian P, Jibara G, Shrager B, et al. Outcomes for cytoreductive surgery and hyperthermic intraperitoneal chemotherapy in the elderly. Surg Oncol. 2013;22:184\u20139.","journal-title":"Surg Oncol"},{"key":"1728_CR19","first-page":"687","volume":"25","author":"A Macr\u00ec","year":"2011","unstructured":"Macr\u00ec A, Saladino E, Trimarchi G, et al. Cytoreductive surgery plus hyperthermic intraperitoneal chemotherapy in elderly patients. In Vivo. 2011;25:687\u201390.","journal-title":"In Vivo"},{"key":"1728_CR20","first-page":"74","volume":"98","author":"JD Spiliotis","year":"2014","unstructured":"Spiliotis JD, Halkia E, Boumis VA, et al. Cytoreductive surgery and HIPEC for peritoneal carcinomatosis in the elderly. Int J Surg Oncol. 2014;98:74\u20135.","journal-title":"Int J Surg Oncol"},{"key":"1728_CR21","doi-asserted-by":"crossref","first-page":"3497","DOI":"10.1245\/s10434-013-3053-z","volume":"20","author":"KI Votanopoulos","year":"2013","unstructured":"Votanopoulos KI, Newman NA, Russell G, et al. Outcomes of Cytoreductive Surgery (CRS) with hyperthermic intraperitoneal chemotherapy (HIPEC) in patients older than 70\u00a0years; survival benefit at considerable morbidity and mortality. Ann Surg Oncol. 2013;20:3497\u2013503.","journal-title":"Ann Surg Oncol"},{"key":"1728_CR22","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1016\/j.ejogrb.2014.05.018","volume":"179","author":"P Cascales-Campos","year":"2014","unstructured":"Cascales-Campos P, Gil J, Gil E, et al. Cytoreduction and HIPEC after neoadjuvant chemotherapy in stage IIIC-IV ovarian cancer. Critical analysis in elderly patients. Eur J Obstet Gynecol Reprod Biol. 2014;179:88\u201393.","journal-title":"Eur J Obstet Gynecol Reprod Biol"},{"key":"1728_CR23","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1016\/j.suronc.2016.03.007","volume":"25","author":"PA Cascales-Campos","year":"2016","unstructured":"Cascales-Campos PA, L\u00f3pez-L\u00f3pez V, Mu\u00f1oz-Casares FC, et al. Morbidity and mortality outcomes after cytoreductive surgery and hyperthermic intraperitoneal chemotherapy in patients aged 75\u00a0years and over: spanish group of peritoneal cancer surgery (GECOP) multicenter study. Surg Oncol. 2016;25:111\u20136.","journal-title":"Surg Oncol"},{"key":"1728_CR24","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1200\/JCO.2009.23.9285","volume":"28","author":"D Elias","year":"2010","unstructured":"Elias D, Gilly F, Boutitie F, et al. Peritoneal colorectal carcinomatosis treated with surgery and perioperative intraperitoneal chemotherapy: retrospective analysis of 523 patients from a multicentric French study. J Clin Oncol. 2010;28:63\u20138.","journal-title":"J Clin Oncol"},{"key":"1728_CR25","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1007\/DCR.0b013e318202f026","volume":"54","author":"H Youssef","year":"2011","unstructured":"Youssef H, Newman C, Chandrakumaran K, Mohamed F, Cecil TD, Moran BJ. Operative findings, early complications, and long-term survival in 456 patients with pseudomyxoma peritonei syndrome of appendiceal origin. Dis Colon Rectum. 2011;54:293.","journal-title":"Dis Colon Rectum"},{"key":"1728_CR26","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1016\/j.currproblcancer.2009.06.008","volume":"33","author":"R McQuellon","year":"2009","unstructured":"McQuellon R, Duckworth KE. Health-related quality of life and cytoreductive surgery plus hyperthermic intraperitoneal chemotherapy. Curr Probl Cancer. 2009;33:203\u201318.","journal-title":"Curr Probl Cancer"},{"key":"1728_CR27","doi-asserted-by":"crossref","first-page":"1156","DOI":"10.1016\/j.ejso.2010.09.004","volume":"36","author":"S Alves","year":"2010","unstructured":"Alves S, Mohamed F, Yadegarfar G, Youssef H, Moran BJ. Prospective longitudinal study of quality of life following cytoreductive surgery and intraperitoneal chemotherapy for pseudomyxoma peritonei. Eur J Surg Oncol. 2010;36:1156\u201361.","journal-title":"Eur J Surg Oncol"}],"container-title":["Clinical and Translational Oncology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s12094-017-1728-9\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s12094-017-1728-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s12094-017-1728-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2017,10,10]],"date-time":"2017-10-10T03:55:29Z","timestamp":1507607729000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s12094-017-1728-9"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,8,10]]},"references-count":27,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2017,11]]}},"alternative-id":["1728"],"URL":"https:\/\/doi.org\/10.1007\/s12094-017-1728-9","relation":{},"ISSN":["1699-048X","1699-3055"],"issn-type":[{"value":"1699-048X","type":"print"},{"value":"1699-3055","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,8,10]]}}}