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Iv\u00e1n M\u00e1rquez-Rodas declares the following COIs: received grants as advisory board, travel and congress accommodation from: BMS, MSD, Roche, Novartis, Amgen, Pierre-Fabre, Merck Serono, Sanofi, Regeneron, Incyte, Astra Zeneca, Bioncotech.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"Data were collected according following ethical principles and ethical professional conduct.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}},{"value":"The authors declare no Research involving Human Participants and\/or Animals.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Human and animal rights"}},{"value":"Our research involved human participants who had obtained informed consents. The study fulfills the declaration of Helsinki ethical standards for research.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Informed constent"}}]}}