{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,5]],"date-time":"2026-03-05T23:24:54Z","timestamp":1772753094214,"version":"3.50.1"},"reference-count":55,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2023,6,8]],"date-time":"2023-06-08T00:00:00Z","timestamp":1686182400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2023,6,8]],"date-time":"2023-06-08T00:00:00Z","timestamp":1686182400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"DOI":"10.13039\/501100011104","name":"Universitat Aut\u00f2noma de Barcelona","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100011104","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Clin Transl Oncol"],"abstract":"<jats:title>Abstract<\/jats:title><jats:sec>\n                <jats:title>Purpose<\/jats:title>\n                <jats:p>Anticancer drug use at the end of life places potential extra burdens on patients and the healthcare system. Previous articles show variability in methods and outcomes; thus, their results are not directly comparable. This scoping review describes the methods and extent of anticancer drug use at end of life.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Methods<\/jats:title>\n                <jats:p>Systematic searches in Medline and Embase were conducted to identify articles reporting anticancer drug use at the end of life.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>We selected 341 eligible publications, identifying key study features including timing of research, disease status, treatment schedule, treatment type, and treatment characteristics. Among the subset of 69 articles of all cancer types published within the last 5\u00a0years, we examined the frequency of anticancer drug use across various end of life periods.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusion<\/jats:title>\n                <jats:p>This comprehensive description of publications on anticancer drug use at end of life underscores the importance of methodological factors when designing studies and comparing outcomes.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1007\/s12094-023-03234-1","type":"journal-article","created":{"date-parts":[[2023,6,8]],"date-time":"2023-06-08T02:01:42Z","timestamp":1686189702000},"page":"178-189","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Frequency of anticancer drug use at the end of life: a scoping review"],"prefix":"10.1007","volume":"26","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7812-9600","authenticated-orcid":false,"given":"Endre","family":"Szigethy","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rosario","family":"Dorantes","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Miguel","family":"Sugra\u00f1es","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2350-4194","authenticated-orcid":false,"given":"Meisser","family":"Madera","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0078-3706","authenticated-orcid":false,"given":"Ivan","family":"Sola","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8850-0960","authenticated-orcid":false,"given":"Gerard","family":"Urr\u00fatia","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1530-3509","authenticated-orcid":false,"given":"Xavier","family":"Bonfill","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2023,6,8]]},"reference":[{"issue":"5","key":"3234_CR1","doi-asserted-by":"publisher","first-page":"1266","DOI":"10.1200\/JCO.2001.19.5.1266","volume":"19","author":"C Doyle","year":"2001","unstructured":"Doyle C, Crump M, Pintilie M, Oza AM. Does palliative chemotherapy palliate? Evaluation of expectations, outcomes, and costs in women receiving chemotherapy for advanced ovarian cancer. J Clin Oncol. 2001;19(5):1266\u201374. https:\/\/doi.org\/10.1200\/JCO.2001.19.5.1266.","journal-title":"J Clin Oncol"},{"issue":"8","key":"3234_CR2","doi-asserted-by":"publisher","first-page":"733","DOI":"10.1056\/NEJMoa1000678","volume":"363","author":"JS Temel","year":"2010","unstructured":"Temel JS, Greer JA, Muzikansky A, Gallagher ER, Admane S, Jackson VA, et al. Early palliative care for patients with metastatic non-small-cell lung cancer. N Engl J Med. 2010;363(8):733\u201342. https:\/\/doi.org\/10.1056\/NEJMoa1000678.","journal-title":"N Engl J Med"},{"issue":"11","key":"3234_CR3","doi-asserted-by":"publisher","first-page":"2375","DOI":"10.1093\/annonc\/mdq778","volume":"22","author":"U Nappa","year":"2011","unstructured":"Nappa U, Lindqvist O, Rasmussen BH, Axelsson B. Palliative chemotherapy during the last month of life. Ann Oncol. 2011;22(11):2375\u201380. https:\/\/doi.org\/10.1093\/annonc\/mdq778.","journal-title":"Ann Oncol"},{"issue":"4","key":"3234_CR4","doi-asserted-by":"publisher","first-page":"826","DOI":"10.1002\/cncr.23620","volume":"113","author":"JS Temel","year":"2008","unstructured":"Temel JS, McCannon J, Greer JA, Jackson VA, Ostler P, Pirl WF, et al. Aggressiveness of care in a prospective cohort of patients with advanced NSCLC. Cancer. 2008;113(4):826\u201333. https:\/\/doi.org\/10.1002\/cncr.23620.","journal-title":"Cancer"},{"issue":"1","key":"3234_CR5","doi-asserted-by":"publisher","first-page":"14","DOI":"10.7399\/fh.2016.40.1.8918","volume":"40","author":"P Taberner Bonastre","year":"2016","unstructured":"Taberner Bonastre P, Taberner Bonastre MT, Soler Company E, Perez-Serrano Lainosa MD. Chemotherapy near the end of life; assessment of the clinical practise in onco-hematological in adult patients. Farm Hosp. 2016;40(1):14\u201324. https:\/\/doi.org\/10.7399\/fh.2016.40.1.8918.","journal-title":"Farm Hosp"},{"key":"3234_CR6","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.g1219","volume":"348","author":"AA Wright","year":"2014","unstructured":"Wright AA, Zhang B, Keating NL, Weeks JC, Prigerson HG. Associations between palliative chemotherapy and adult cancer patients\u2019 end of life care and place of death: prospective cohort study. BMJ (Online). 2014;348: g1219. https:\/\/doi.org\/10.1136\/bmj.g1219.","journal-title":"BMJ (Online)"},{"issue":"4","key":"3234_CR7","doi-asserted-by":"publisher","first-page":"381","DOI":"10.1634\/theoncologist.2012-0279","volume":"18","author":"SY Zafar","year":"2013","unstructured":"Zafar SY, Peppercorn JM, Schrag D, Taylor DH, Goetzinger AM, Zhong X, et al. The financial toxicity of cancer treatment: a pilot study assessing out-of-pocket expenses and the insured cancer patient\u2019s experience. Oncologist. 2013;18(4):381\u201390. https:\/\/doi.org\/10.1634\/theoncologist.2012-0279.","journal-title":"Oncologist"},{"issue":"6","key":"3234_CR8","doi-asserted-by":"publisher","first-page":"778","DOI":"10.1001\/jamaoncol.2015.2378","volume":"1","author":"HG Prigerson","year":"2015","unstructured":"Prigerson HG, Bao Y, Shah MA, Paulk ME, LeBlanc TW, Schneider BJ, et al. Chemotherapy use, performance status, and quality of life at the end of life. JAMA Oncol. 2015;1(6):778\u201384. https:\/\/doi.org\/10.1001\/jamaoncol.2015.2378.","journal-title":"JAMA Oncol"},{"issue":"8","key":"3234_CR9","doi-asserted-by":"publisher","first-page":"929","DOI":"10.1089\/jpm.2010.0522","volume":"14","author":"AM Saito","year":"2011","unstructured":"Saito AM, Landrum MB, Neville BA, Ayanian JZ, Weeks JC, Earle CC. Hospice care and survival among elderly patients with lung cancer. J Palliat Med. 2011;14(8):929\u201339. https:\/\/doi.org\/10.1089\/jpm.2010.0522.","journal-title":"J Palliat Med"},{"issue":"1","key":"3234_CR10","doi-asserted-by":"publisher","first-page":"77","DOI":"10.1016\/j.jpainsymman.2013.02.021","volume":"47","author":"D Hui","year":"2014","unstructured":"Hui D, Nooruddin Z, Didwaniya N, Dev R, De La Cruz M, Kim SH, et al. Concepts and definitions for \u201cactively dying,\u201d \u201cend of life,\u201d \u201cterminally ill,\u201d \u201cterminal care,\u201d and \u201ctransition of care\u201d: a systematic review. J Pain Symptom Manag. 2014;47(1):77\u201389. https:\/\/doi.org\/10.1016\/j.jpainsymman.2013.02.021.","journal-title":"J Pain Symptom Manag"},{"issue":"3","key":"3234_CR11","doi-asserted-by":"publisher","first-page":"1421","DOI":"10.1007\/s00520-015-3031-z","volume":"24","author":"WL Chan","year":"2016","unstructured":"Chan WL, Lam KO, Siu WK, Yuen KK. Chemotherapy at end-of-life: an integration of oncology and palliative team. Support Care Cancer. 2016;24(3):1421\u20137. https:\/\/doi.org\/10.1007\/s00520-015-3031-z.","journal-title":"Support Care Cancer"},{"issue":"4","key":"3234_CR12","doi-asserted-by":"publisher","first-page":"555","DOI":"10.4143\/crt.2014.200","volume":"47","author":"Y Choi","year":"2015","unstructured":"Choi Y, Keam B, Kim TM, Lee SH, Kim DW, Heo DS. Cancer treatment near the end-of-life becomes more aggressive: changes in trend during 10 years at a single institute. Cancer Res Treat. 2015;47(4):555\u201363. https:\/\/doi.org\/10.4143\/crt.2014.200.","journal-title":"Cancer Res Treat"},{"issue":"15","key":"3234_CR13","doi-asserted-by":"publisher","first-page":"3606","DOI":"10.1182\/bloodadvances.2020001767","volume":"4","author":"PC Egan","year":"2020","unstructured":"Egan PC, LeBlanc TW, Olszewski AJ. End-of-life care quality outcomes among Medicare beneficiaries with hematologic malignancies. Blood Adv. 2020;4(15):3606\u201314. https:\/\/doi.org\/10.1182\/bloodadvances.2020001767.","journal-title":"Blood Adv"},{"key":"3234_CR14","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.18.02067","author":"P Fang","year":"2019","unstructured":"Fang P, Jagsi R, He W, Lei X, Campbell EG, Giordano SH, et al. Rising and falling trends in the use of chemotherapy and targeted therapy near the end of life in older patients with cancer. J Clin Oncol. 2019. https:\/\/doi.org\/10.1200\/JCO.18.02067.","journal-title":"J Clin Oncol"},{"issue":"2","key":"3234_CR15","doi-asserted-by":"publisher","first-page":"116","DOI":"10.1016\/j.jgo.2015.11.007","volume":"7","author":"SY Wang","year":"2016","unstructured":"Wang SY, Hall J, Pollack CE, Adelson K, Bradley EH, Long JB, et al. Trends in end-of-life cancer care in the Medicare program. J Geriatr Oncol. 2016;7(2):116\u201325. https:\/\/doi.org\/10.1016\/j.jgo.2015.11.007.","journal-title":"J Geriatr Oncol"},{"issue":"11","key":"3234_CR16","doi-asserted-by":"publisher","first-page":"e627","DOI":"10.1016\/S1470-2045(19)30496-6","volume":"20","author":"NC Abedini","year":"2019","unstructured":"Abedini NC, Hechtman RK, Singh AD, Khateeb R, Mann J, Townsend W, et al. Interventions to reduce aggressive care at end of life among patients with cancer: a systematic review. Lancet Oncol. 2019;20(11):e627\u201336. https:\/\/doi.org\/10.1016\/S1470-2045(19)30496-6.","journal-title":"Lancet Oncol"},{"issue":"10","key":"3234_CR17","doi-asserted-by":"publisher","first-page":"1167","DOI":"10.1177\/0269216314533813","volume":"28","author":"JM Langton","year":"2014","unstructured":"Langton JM, Blanch B, Drew AK, Haas M, Ingham JM, Pearson SA. Retrospective studies of end-of-life resource utilization and costs in cancer care using health administrative data: a systematic review. Palliat Med. 2014;28(10):1167\u201396. https:\/\/doi.org\/10.1177\/0269216314533813.","journal-title":"Palliat Med"},{"issue":"10","key":"3234_CR18","doi-asserted-by":"publisher","first-page":"877","DOI":"10.1093\/jjco\/hyy117","volume":"48","author":"Y Sato","year":"2018","unstructured":"Sato Y, Miyashita M, Sato K, Fujimori K, Ishikawa KB, Horiguchi H, et al. End-of-life care for cancer patients in Japanese acute care hospitals: a nationwide retrospective administrative database survey. Jpn J Clin Oncol. 2018;48(10):877\u201383. https:\/\/doi.org\/10.1093\/jjco\/hyy117.","journal-title":"Jpn J Clin Oncol"},{"issue":"9","key":"3234_CR19","doi-asserted-by":"publisher","first-page":"1509","DOI":"10.1177\/0269216318786393","volume":"32","author":"K Skov Benthien","year":"2018","unstructured":"Skov Benthien K, Adsersen M, Petersen MA, Soelberg Vadstrup E, Sjogren P, Groenvold M. Is specialized palliative cancer care associated with use of antineoplastic treatment at the end of life? A population-based cohort study. Palliat Med. 2018;32(9):1509\u201317. https:\/\/doi.org\/10.1177\/0269216318786393.","journal-title":"Palliat Med"},{"issue":"4","key":"3234_CR20","doi-asserted-by":"publisher","first-page":"809","DOI":"10.1093\/annonc\/mdw654","volume":"28","author":"P Rochigneux","year":"2017","unstructured":"Rochigneux P, Raoul JL, Beaussant Y, Aubry R, Goldwasser F, Tournigand C, et al. Use of chemotherapy near the end of life: what factors matter? Ann Oncol. 2017;28(4):809\u201317. https:\/\/doi.org\/10.1093\/annonc\/mdw654.","journal-title":"Ann Oncol"},{"issue":"15_suppl","key":"3234_CR21","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2018.36.15_suppl.e22014","volume":"36","author":"J Webster","year":"2018","unstructured":"Webster J, Scott J, Johnson KA. Impact of chemotherapy provided to patients late in life on resource utilization and cost of care. J Clin Oncol. 2018;36(15_suppl): e22014. https:\/\/doi.org\/10.1200\/JCO.2018.36.15_suppl.e22014.","journal-title":"J Clin Oncol"},{"issue":"1","key":"3234_CR22","doi-asserted-by":"publisher","first-page":"143","DOI":"10.1186\/s12874-018-0611-x","volume":"18","author":"Z Munn","year":"2018","unstructured":"Munn Z, Peters MDJ, Stern C, Tufanaru C, McArthur A, Aromataris E. Systematic review or scoping review? Guidance for authors when choosing between a systematic or scoping review approach. BMC Med Res Methodol. 2018;18(1):143. https:\/\/doi.org\/10.1186\/s12874-018-0611-x.","journal-title":"BMC Med Res Methodol"},{"key":"3234_CR23","doi-asserted-by":"publisher","first-page":"15","DOI":"10.1186\/s12874-016-0116-4","volume":"16","author":"AC Tricco","year":"2016","unstructured":"Tricco AC, Lillie E, Zarin W, O\u2019Brien K, Colquhoun H, Kastner M, et al. A scoping review on the conduct and reporting of scoping reviews. BMC Med Res Methodol. 2016;16:15. https:\/\/doi.org\/10.1186\/s12874-016-0116-4.","journal-title":"BMC Med Res Methodol"},{"key":"3234_CR24","doi-asserted-by":"publisher","first-page":"156","DOI":"10.1016\/j.jclinepi.2020.10.009","volume":"130","author":"H Khalil","year":"2021","unstructured":"Khalil H, Peters MD, Tricco AC, Pollock D, Alexander L, McInerney P, et al. Conducting high quality scoping reviews-challenges and solutions. J Clin Epidemiol. 2021;130:156\u201360. https:\/\/doi.org\/10.1016\/j.jclinepi.2020.10.009.","journal-title":"J Clin Epidemiol"},{"key":"3234_CR25","doi-asserted-by":"publisher","first-page":"29","DOI":"10.1016\/j.jclinepi.2015.12.011","volume":"73","author":"AC Tricco","year":"2016","unstructured":"Tricco AC, Antony J, Soobiah C, Kastner M, MacDonald H, Cogo E, et al. Knowledge synthesis methods for integrating qualitative and quantitative data: a scoping review reveals poor operationalization of the methodological steps. J Clin Epidemiol. 2016;73:29\u201335. https:\/\/doi.org\/10.1016\/j.jclinepi.2015.12.011.","journal-title":"J Clin Epidemiol"},{"issue":"1","key":"3234_CR26","doi-asserted-by":"publisher","first-page":"45","DOI":"10.1186\/s13643-023-02178-5","volume":"12","author":"F Campbell","year":"2023","unstructured":"Campbell F, Tricco AC, Munn Z, Pollock D, Saran A, Sutton A, et al. Mapping reviews, scoping reviews, and evidence and gap maps (EGMs): the same but different\u2014the \u201cBig Picture\u201d review family. Syst Rev. 2023;12(1):45. https:\/\/doi.org\/10.1186\/s13643-023-02178-5.","journal-title":"Syst Rev"},{"issue":"7","key":"3234_CR27","doi-asserted-by":"publisher","first-page":"467","DOI":"10.7326\/M18-0850","volume":"169","author":"AC Tricco","year":"2018","unstructured":"Tricco AC, Lillie E, Zarin W, O\u2019Brien KK, Colquhoun H, Levac D, et al. PRISMA extension for scoping reviews (PRISMA-ScR): checklist and explanation. Ann Intern Med. 2018;169(7):467\u201373. https:\/\/doi.org\/10.7326\/M18-0850.","journal-title":"Ann Intern Med"},{"key":"3234_CR28","doi-asserted-by":"publisher","first-page":"207","DOI":"10.1016\/j.socscimed.2014.12.007","volume":"131","author":"C Davis","year":"2015","unstructured":"Davis C. Drugs, cancer and end-of-life care: a case study of pharmaceuticalization? Soc Sci Med. 2015;131:207\u201314. https:\/\/doi.org\/10.1016\/j.socscimed.2014.12.007.","journal-title":"Soc Sci Med"},{"issue":"1","key":"3234_CR29","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1186\/s12904-018-0348-7","volume":"17","author":"TK Jang","year":"2018","unstructured":"Jang TK, Kim DY, Lee SW, Park JY, Suh DS, Kim JH, et al. Trends in treatment during the last stages of life in end-stage gynecologic cancer patients who received active palliative chemotherapy: a comparative analysis of 10-year data in a single institution. BMC Palliat Care. 2018;17(1):1\u20138. https:\/\/doi.org\/10.1186\/s12904-018-0348-7.","journal-title":"BMC Palliat Care"},{"key":"3234_CR30","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2022.809761","volume":"13","author":"Z Liu","year":"2022","unstructured":"Liu Z, Ren Y, Weng S, Xu H, Li L, Han X. A new trend in cancer treatment: the combination of epigenetics and immunotherapy. Front Immunol. 2022;13: 809761. https:\/\/doi.org\/10.3389\/fimmu.2022.809761.","journal-title":"Front Immunol"},{"issue":"3","key":"3234_CR31","doi-asserted-by":"publisher","first-page":"301","DOI":"10.1634\/theoncologist.2014-0341","volume":"21","author":"A Young","year":"2016","unstructured":"Young A, Marshall E, Krzyzanowska M, Robinson B, Brown S, Collinson F, et al. Responding to acute care needs of patients with cancer: recent trends across continents. Oncologist. 2016;21(3):301\u20137. https:\/\/doi.org\/10.1634\/theoncologist.2014-0341.","journal-title":"Oncologist"},{"issue":"11","key":"3234_CR32","doi-asserted-by":"publisher","first-page":"1191","DOI":"10.1111\/imj.12245","volume":"43","author":"N Zdenkowski","year":"2013","unstructured":"Zdenkowski N, Cavenagh J, Ku YC, Bisquera A, Bonaventura A. Administration of chemotherapy with palliative intent in the last 30 days of life: the balance between palliation and chemotherapy. Intern Med J. 2013;43(11):1191\u20138. https:\/\/doi.org\/10.1111\/imj.12245.","journal-title":"Intern Med J"},{"issue":"4","key":"3234_CR33","doi-asserted-by":"publisher","first-page":"361","DOI":"10.1634\/theoncologist.2016-0277","volume":"22","author":"S Dalal","year":"2017","unstructured":"Dalal S, Bruera E. End-of-life care matters: palliative cancer care results in better care and lower costs. Oncologist. 2017;22(4):361\u20138. https:\/\/doi.org\/10.1634\/theoncologist.2016-0277.","journal-title":"Oncologist"},{"issue":"5","key":"3234_CR34","doi-asserted-by":"publisher","first-page":"616","DOI":"10.1089\/jpm.2017.0445","volume":"21","author":"MA Mollica","year":"2018","unstructured":"Mollica MA, Kent EE, Castro KM, Ellis EM, Ferrer RA, Falisi AL, et al. Perspectives on palliative care in cancer clinical trials: diverse meanings from multidisciplinary cancer care providers. J Palliat Med. 2018;21(5):616\u201321. https:\/\/doi.org\/10.1089\/jpm.2017.0445.","journal-title":"J Palliat Med"},{"issue":"6","key":"3234_CR35","doi-asserted-by":"publisher","first-page":"711","DOI":"10.1200\/JGO.2016.007385","volume":"3","author":"D Low","year":"2017","unstructured":"Low D, Merkel EC, Menon M, Lyman GH, Ddungu H, Namukwaya E, et al. Chemotherapy use at the end of life in Uganda. J Glob Oncol. 2017;3(6):711\u20139. https:\/\/doi.org\/10.1200\/JGO.2016.007385.","journal-title":"J Glob Oncol"},{"key":"3234_CR36","doi-asserted-by":"publisher","unstructured":"Dying in America: improving quality and honoring individual preferences near the end of life. Mil Med. 2015;180(4):365\u20137. https:\/\/doi.org\/10.7205\/MILMED-D-15-00005.","DOI":"10.7205\/MILMED-D-15-00005"},{"key":"3234_CR37","unstructured":"National quality Forum: palliative and end-of-life care 2015\u20132016 technical report. 2016 [cited 2022 10 May]. Available from: http:\/\/www.qualityforum.org\/publications\/2016\/12\/palliative_and_end-of-life_care_2015-2016.aspx."},{"issue":"2","key":"3234_CR38","doi-asserted-by":"publisher","first-page":"315","DOI":"10.1200\/JCO.2004.08.136","volume":"22","author":"CC Earle","year":"2004","unstructured":"Earle CC, Neville BA, Landrum MB, Ayanian JZ, Block SD, Weeks JC. Trends in the aggressiveness of cancer care near the end of life. J Clin Oncol. 2004;22(2):315\u201321. https:\/\/doi.org\/10.1200\/JCO.2004.08.136.","journal-title":"J Clin Oncol"},{"issue":"2","key":"3234_CR39","doi-asserted-by":"publisher","first-page":"302","DOI":"10.1111\/jgs.15671","volume":"67","author":"KB Lasater","year":"2019","unstructured":"Lasater KB, Sloane DM, McHugh MD, Aiken LH. Quality of end-of-life care and its association with nurse practice environments in US hospitals. J Am Geriatr Soc. 2019;67(2):302\u20138. https:\/\/doi.org\/10.1111\/jgs.15671.","journal-title":"J Am Geriatr Soc"},{"key":"3234_CR40","unstructured":"National Quality Forum: National voluntary consensus standards for quality of cancer care 2009 [cited 2022 10 May]. Available from: https:\/\/www.qualityforum.org\/publications\/2009\/05\/National_voluntary_consensus_standards_for_Quality_of_Cancer_Care.aspx."},{"key":"3234_CR41","doi-asserted-by":"publisher","DOI":"10.3390\/ijerph17144955","author":"J Cerni","year":"2020","unstructured":"Cerni J, Rhee J, Hosseinzadeh H. End-of-life cancer care resource utilisation in rural versus urban settings: a systematic review. Int J Environ Res Public Health. 2020. https:\/\/doi.org\/10.3390\/ijerph17144955.","journal-title":"Int J Environ Res Public Health"},{"issue":"1","key":"3234_CR42","doi-asserted-by":"publisher","first-page":"35","DOI":"10.1186\/s12904-019-0419-4","volume":"18","author":"I Colombet","year":"2019","unstructured":"Colombet I, Bouleuc C, Piolot A, Vilfaillot A, Jaulmes H, Voisin-Saltiel S, et al. Multicentre analysis of intensity of care at the end-of-life in patients with advanced cancer, combining health administrative data with hospital records: variations in practice call for routine quality evaluation. BMC Palliat Care. 2019;18(1):35. https:\/\/doi.org\/10.1186\/s12904-019-0419-4.","journal-title":"BMC Palliat Care"},{"key":"3234_CR43","doi-asserted-by":"publisher","DOI":"10.1200\/op.20.00217","author":"AR Khaki","year":"2020","unstructured":"Khaki AR, Xu Y, Cheung WY, Li L, Fedorenko C, Grivas P, et al. Comparison of health care utilization at the end of life among patients with cancer in Alberta, Canada, versus Washington State. JCO Oncol Pract. 2020. https:\/\/doi.org\/10.1200\/op.20.00217.","journal-title":"JCO Oncol Pract"},{"issue":"1","key":"3234_CR44","doi-asserted-by":"publisher","first-page":"12","DOI":"10.1177\/082585970602200103","volume":"22","author":"L Barbera","year":"2006","unstructured":"Barbera L, Paszat L, Chartier C. Indicators of poor quality end-of-life cancer care in Ontario. J Palliat Care. 2006;22(1):12\u20137.","journal-title":"J Palliat Care"},{"issue":"8","key":"3234_CR45","doi-asserted-by":"publisher","first-page":"992","DOI":"10.1097\/00005650-200308000-00012","volume":"41","author":"F Burge","year":"2003","unstructured":"Burge F, Lawson B, Johnston G. Family physician continuity of care and emergency department use in end-of-life cancer care. Med Care. 2003;41(8):992\u20131001.","journal-title":"Med Care"},{"issue":"15","key":"3234_CR46","doi-asserted-by":"publisher","first-page":"3732","DOI":"10.1002\/cncr.25077","volume":"116","author":"NL Keating","year":"2010","unstructured":"Keating NL, Landrum MB, Lamont EB, Earle CC, Bozeman SR, McNeil BJ. End-of-life care for older cancer patients in the veterans health administration versus the private sector. Cancer. 2010;116(15):3732\u20139. https:\/\/doi.org\/10.1002\/cncr.25077.","journal-title":"Cancer"},{"issue":"21","key":"3234_CR47","doi-asserted-by":"publisher","first-page":"5003","DOI":"10.1002\/cncr.26115","volume":"117","author":"KM Sheffield","year":"2011","unstructured":"Sheffield KM, Boyd CA, Benarroch-Gampel J, Kuo YF, Cooksley CD, Riall TS. End-of-life care in Medicare beneficiaries dying with pancreatic cancer. Cancer. 2011;117(21):5003\u201312. https:\/\/doi.org\/10.1002\/cncr.26115.","journal-title":"Cancer"},{"issue":"2","key":"3234_CR48","doi-asserted-by":"publisher","first-page":"231","DOI":"10.1016\/j.jpainsymman.2013.03.021","volume":"47","author":"W Hu","year":"2014","unstructured":"Hu W, Yasui Y, White J, Winget M. Aggressiveness of end-of-life care for patients with colorectal cancer in Salberta, Canada: 2006\u20132009. J Pain Symptom Manag. 2014;47(2):231\u201344. https:\/\/doi.org\/10.1016\/j.jpainsymman.2013.03.021.","journal-title":"J Pain Symptom Manag"},{"issue":"1","key":"3234_CR49","doi-asserted-by":"publisher","first-page":"11","DOI":"10.1007\/s11606-007-0422-y","volume":"23","author":"NL Keating","year":"2008","unstructured":"Keating NL, Landrum MB, Guadagnoli E, Winer EP, Ayanian JZ. Care in the months before death and hospice enrollment among older women with advanced breast cancer. J Gen Intern Med. 2008;23(1):11\u20138. https:\/\/doi.org\/10.1007\/s11606-007-0422-y.","journal-title":"J Gen Intern Med"},{"issue":"4","key":"3234_CR50","doi-asserted-by":"publisher","first-page":"728","DOI":"10.1200\/JCO.2003.06.142","volume":"21","author":"EP McCarthy","year":"2003","unstructured":"McCarthy EP, Burns RB, Davis RB, Phillips RS. Barriers to hospice care among older patients dying with lung and colorectal cancer. J Clin Oncol. 2003;21(4):728\u201335. https:\/\/doi.org\/10.1200\/JCO.2003.06.142.","journal-title":"J Clin Oncol"},{"issue":"7","key":"3234_CR51","doi-asserted-by":"publisher","first-page":"2275","DOI":"10.1007\/s00520-018-4063-y","volume":"26","author":"J Walter","year":"2018","unstructured":"Walter J, Tufman A, Leidl R, Holle R, Schwarzkopf L. Rural versus urban differences in end-of-life care for lung cancer patients in Germany. Support Care Cancer. 2018;26(7):2275\u201383. https:\/\/doi.org\/10.1007\/s00520-018-4063-y.","journal-title":"Support Care Cancer"},{"issue":"7","key":"3234_CR52","doi-asserted-by":"publisher","first-page":"1203","DOI":"10.1200\/JCO.2009.25.4672","volume":"28","author":"JW Mack","year":"2010","unstructured":"Mack JW, Weeks JC, Wright AA, Block SD, Prigerson HG. End-of-life discussions, goal attainment, and distress at the end of life: predictors and outcomes of receipt of care consistent with preferences. J Clin Oncol. 2010;28(7):1203\u20138. https:\/\/doi.org\/10.1200\/JCO.2009.25.4672.","journal-title":"J Clin Oncol"},{"issue":"19","key":"3234_CR53","doi-asserted-by":"publisher","first-page":"4656","DOI":"10.1002\/cncr.25217","volume":"116","author":"AA Wright","year":"2010","unstructured":"Wright AA, Mack JW, Kritek PA, Balboni TA, Massaro AF, Matulonis UA, et al. Influence of patients\u2019 preferences and treatment site on cancer patients\u2019 end-of-life care. Cancer. 2010;116(19):4656\u201363. https:\/\/doi.org\/10.1002\/cncr.25217.","journal-title":"Cancer"},{"issue":"3","key":"3234_CR54","doi-asserted-by":"publisher","first-page":"413","DOI":"10.3390\/genes1030413","volume":"1","author":"A Borchers","year":"2010","unstructured":"Borchers A, Pieler T. Programming pluripotent precursor cells derived from Xenopus embryos to generate specific tissues and organs. Genes. 2010;1(3):413\u201326. https:\/\/doi.org\/10.3390\/genes1030413.","journal-title":"Genes"},{"key":"3234_CR55","doi-asserted-by":"publisher","first-page":"1428","DOI":"10.1200\/GO.20.00351","volume":"6","author":"AR Jazieh","year":"2020","unstructured":"Jazieh AR, Akbulut H, Curigliano G, Rogado A, Alsharm AA, Razis ED, et al. Impact of the COVID-19 pandemic on cancer care: a global collaborative study. JCO Glob Oncol. 2020;6:1428\u201338. https:\/\/doi.org\/10.1200\/GO.20.00351.","journal-title":"JCO Glob Oncol"}],"container-title":["Clinical and Translational Oncology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12094-023-03234-1.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s12094-023-03234-1\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12094-023-03234-1.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,1,2]],"date-time":"2024-01-02T14:29:37Z","timestamp":1704205777000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s12094-023-03234-1"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,6,8]]},"references-count":55,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2024,1]]}},"alternative-id":["3234"],"URL":"https:\/\/doi.org\/10.1007\/s12094-023-03234-1","relation":{},"ISSN":["1699-3055"],"issn-type":[{"value":"1699-3055","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,6,8]]},"assertion":[{"value":"26 March 2023","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"25 May 2023","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"8 June 2023","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors have no relevant financial or non-financial interests to disclose.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"Not applicable.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Not applicable.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}}]}}