{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,24]],"date-time":"2026-10-24T01:42:47Z","timestamp":1792806167762,"version":"4.5.0"},"reference-count":30,"publisher":"Springer Science and Business Media LLC","issue":"11","license":[{"start":{"date-parts":[[2026,5,22]],"date-time":"2026-05-22T00:00:00Z","timestamp":1779408000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2026,5,22]],"date-time":"2026-05-22T00:00:00Z","timestamp":1779408000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Clin Transl Oncol"],"DOI":"10.1007\/s12094-026-04404-7","type":"journal-article","created":{"date-parts":[[2026,5,22]],"date-time":"2026-05-22T16:25:53Z","timestamp":1779467153000},"page":"5271-5279","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Comparison of LENT, PROMISE, and RECLS scores in malignant pleural effusions"],"prefix":"10.1007","volume":"28","author":[{"ORCID":"https:\/\/orcid.org\/0009-0006-7121-8578","authenticated-orcid":false,"given":"Hasan Emre","family":"Yildirim","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0212-0439","authenticated-orcid":false,"given":"Hasan Ekrem","family":"Camas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0641-5229","authenticated-orcid":false,"given":"Suleyman Emre","family":"Akin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2575-1882","authenticated-orcid":false,"given":"Isa","family":"Dongel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7369-6710","authenticated-orcid":false,"given":"Rasih","family":"Yazkan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,5,22]]},"reference":[{"key":"4404_CR1","doi-asserted-by":"publisher","DOI":"10.1016\/j.rmed.2022.106802","volume":"196","author":"SI Bashour","year":"2022","unstructured":"Bashour SI, Mankidy BJ, Lazarus DR. Update on the diagnosis and management of malignant pleural effusions. Respir Med. 2022;196:106802.","journal-title":"Respir Med"},{"issue":"1","key":"4404_CR2","doi-asserted-by":"publisher","first-page":"181","DOI":"10.1016\/j.ccm.2017.11.004","volume":"39","author":"R Asciak","year":"2018","unstructured":"Asciak R, Rahman NM. Malignant pleural effusion: from diagnostics to therapeutics. Clin Chest Med. 2018;39(1):181\u201393.","journal-title":"Clin Chest Med"},{"issue":"140","key":"4404_CR3","doi-asserted-by":"publisher","first-page":"189","DOI":"10.1183\/16000617.0019-2016","volume":"25","author":"I Psallidas","year":"2016","unstructured":"Psallidas I, Kalomenidis I, Porcel JM, Robinson BW, Stathopoulos GT. Malignant pleural effusion: from bench to bedside. Eur Respir Rev. 2016;25(140):189\u201398.","journal-title":"Eur Respir Rev"},{"issue":"1","key":"4404_CR4","doi-asserted-by":"publisher","first-page":"47","DOI":"10.1186\/s12931-024-02684-7","volume":"25","author":"F Gonnelli","year":"2024","unstructured":"Gonnelli F, Hassan W, Bonifazi M, Pinelli V, Bedawi EO, Porcel JM, et al. Malignant pleural effusion: current understanding and therapeutic approach. Respir Res. 2024;25(1):47.","journal-title":"Respir Res"},{"issue":"4","key":"4404_CR5","doi-asserted-by":"publisher","first-page":"1534","DOI":"10.1016\/j.chest.2021.05.026","volume":"160","author":"SR Mummadi","year":"2021","unstructured":"Mummadi SR, Stoller JK, Lopez R, Kailasam K, Gillespie CT, Hahn PY. Epidemiology of adult pleural disease in the United States. Chest. 2021;160(4):1534\u201351.","journal-title":"Chest"},{"issue":"2","key":"4404_CR6","doi-asserted-by":"publisher","first-page":"369","DOI":"10.54005\/geneltip.1639378","volume":"35","author":"SE Ak\u0131n","year":"2025","unstructured":"Ak\u0131n SE, Y\u0131ld\u0131r\u0131m HE, Ya\u011fc\u0131 S, Otlu U, \u00c7ama\u015f HE, Erdo\u011fan M, et al. The diagnostic role of PET\/CT in patients with malignant pleural effusion. Genel T\u0131p Derg. 2025;35(2):369\u201373.","journal-title":"Genel T\u0131p Derg"},{"key":"4404_CR7","doi-asserted-by":"publisher","DOI":"10.3389\/fonc.2022.961440","volume":"12","author":"Y Zhao","year":"2022","unstructured":"Zhao Y, Yu L, Wang L, Wu Y, Chen H, Wang Q, et al. Current status of and progress in the treatment of malignant pleural effusion of lung cancer. Front Oncol. 2022;12:961440.","journal-title":"Front Oncol"},{"issue":"22","key":"4404_CR8","doi-asserted-by":"publisher","first-page":"2383","DOI":"10.1001\/jama.2012.5535","volume":"307","author":"HE Davies","year":"2012","unstructured":"Davies HE, Mishra EK, Kahan BC, Wrightson JM, Stanton AE, Guhan A, et al. Effect of an indwelling pleural catheter vs chest tube and talc pleurodesis for relieving dyspnea in patients with malignant pleural effusion: the TIME2 randomized controlled trial. JAMA. 2012;307(22):2383\u20139.","journal-title":"JAMA"},{"issue":"1","key":"4404_CR9","doi-asserted-by":"publisher","first-page":"60","DOI":"10.1001\/jama.2019.19997","volume":"323","author":"R Bhatnagar","year":"2020","unstructured":"Bhatnagar R, Piotrowska HE, Laskawiec-Szkonter M, Kahan BC, Luengo-Fernandez R, Pepperell JC, et al. Effect of thoracoscopic talc poudrage vs talc slurry via chest tube on pleurodesis failure rate among patients with malignant pleural effusions: a randomized clinical trial. JAMA. 2020;323(1):60\u20139.","journal-title":"JAMA"},{"issue":"12","key":"4404_CR10","doi-asserted-by":"publisher","first-page":"1098","DOI":"10.1136\/thoraxjnl-2014-205285","volume":"69","author":"AO Clive","year":"2014","unstructured":"Clive AO, Kahan BC, Hooper CE, Bhatnagar R, Morley AJ, Zahan-Evans N, et al. Predicting survival in malignant pleural effusion: development and validation of the LENT prognostic score. Thorax. 2014;69(12):1098\u2013104.","journal-title":"Thorax"},{"issue":"7","key":"4404_CR11","doi-asserted-by":"publisher","first-page":"930","DOI":"10.1016\/S1470-2045(18)30294-8","volume":"19","author":"I Psallidas","year":"2018","unstructured":"Psallidas I, Kanellakis NI, Gerry S, Thezenas ML, Charles PD, Samsonova A, et al. Development and validation of response markers to predict survival and pleurodesis success in patients with malignant pleural effusion (PROMISE): a multicohort analysis. Lancet Oncol. 2018;19(7):930\u20139.","journal-title":"Lancet Oncol"},{"issue":"3","key":"4404_CR12","doi-asserted-by":"publisher","first-page":"1318","DOI":"10.21037\/tlcr-20-1191","volume":"10","author":"T Zhang","year":"2021","unstructured":"Zhang T, Chen X, Wan B, Xu Y, Liu H, Lv T, et al. Development of RECLS score to predict survival in lung cancer patients with malignant pleural effusion. Transl Lung Cancer Res. 2021;10(3):1318\u201326.","journal-title":"Transl Lung Cancer Res"},{"key":"4404_CR13","doi-asserted-by":"publisher","unstructured":"Jovanovic D. Etiopathogenesis of malignant pleural effusion. AME Med J. 2021;6:37. https:\/\/doi.org\/10.21037\/amj-20-188.","DOI":"10.21037\/amj-20-188"},{"issue":"4","key":"4404_CR14","doi-asserted-by":"publisher","first-page":"654","DOI":"10.1111\/resp.12496","volume":"20","author":"JM Porcel","year":"2012","unstructured":"Porcel JM, Gasol A, Bielsa S, Civit C, Light RW, Salud A. Clinical features and survival of lung cancer patients with pleural effusions. Respirology. 2012;20(4):654\u20139.","journal-title":"Respirology"},{"key":"4404_CR15","doi-asserted-by":"publisher","unstructured":"Arnold DT, De Fonseka D, Perry S, Morley A, Harvey JE, Medford A, et al. Investigating unilateral pleural effusions: the role of cytology. Eur Respir J. 2018;52(5):1801254. https:\/\/doi.org\/10.1183\/13993003.01254-2018.","DOI":"10.1183\/13993003.01254-2018"},{"issue":"10","key":"4404_CR16","doi-asserted-by":"publisher","first-page":"1188","DOI":"10.1016\/j.amjmed.2022.04.017","volume":"135","author":"S Gayen","year":"2022","unstructured":"Gayen S. Malignant pleural effusion: presentation, diagnosis, and management. Am J Med. 2022;135(10):1188\u201392.","journal-title":"Am J Med"},{"issue":"8","key":"4404_CR17","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0000000000028130","volume":"101","author":"Z Yousaf","year":"2022","unstructured":"Yousaf Z, Ata F, Chaudhary H, Krause F, Illigens BM, Siepmann T. Etiology, pathological characteristics, and clinical management of black pleural effusion: a systematic review. Medicine (Baltimore). 2022;101(8):e28130.","journal-title":"Medicine (Baltimore)"},{"issue":"19","key":"4404_CR18","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0000000000025748","volume":"100","author":"J Roh","year":"2021","unstructured":"Roh J, Ahn HY, Kim I, Son JH, Seol HY, Kim MH, et al. Clinical course of asymptomatic malignant pleural effusion in non-small cell lung cancer patients: a multicenter retrospective study. Medicine (Baltimore). 2021;100(19):e25748.","journal-title":"Medicine (Baltimore)"},{"issue":"5","key":"4404_CR19","doi-asserted-by":"publisher","first-page":"615","DOI":"10.1002\/dc.24433","volume":"49","author":"M Lew","year":"2021","unstructured":"Lew M, Cantley R, Heider A, Jing X. Diagnosis and categorization of malignant effusions: a 6-year review from a single academic institution. Diagn Cytopathol. 2021;49(5):615\u201321.","journal-title":"Diagn Cytopathol"},{"issue":"1","key":"4404_CR20","doi-asserted-by":"publisher","first-page":"99","DOI":"10.1186\/s12935-022-02518-w","volume":"22","author":"P Peng","year":"2022","unstructured":"Peng P, Yang Y, Du J, Zhai K, Shi HZ. Prognostic biomarkers of malignant patients with pleural effusion: a systematic review and meta-analysis. Cancer Cell Int. 2022;22(1):99.","journal-title":"Cancer Cell Int"},{"issue":"6","key":"4404_CR21","doi-asserted-by":"publisher","first-page":"791","DOI":"10.1111\/crj.12292","volume":"10","author":"US Kasapoglu","year":"2016","unstructured":"Kasapoglu US, Arinc S, Gungor S, Irmak I, Guney P, Aksoy F, et al. Prognostic factors affecting survival in non-small cell lung carcinoma patients with malignant pleural effusions. Clin Respir J. 2016;10(6):791\u20139.","journal-title":"Clin Respir J"},{"key":"4404_CR22","doi-asserted-by":"publisher","first-page":"409","DOI":"10.1016\/j.jss.2019.06.068","volume":"244","author":"DC Foote","year":"2019","unstructured":"Foote DC, Burke CR, Pandian B, Banks S, Haug KL, Hipp M, et al. Gender disparity in referral for definitive care of malignant pleural effusions. J Surg Res. 2019;244:409\u201316.","journal-title":"J Surg Res"},{"key":"4404_CR23","doi-asserted-by":"publisher","DOI":"10.6061\/clinics\/2021\/e2515","volume":"76","author":"Z Ren","year":"2021","unstructured":"Ren Z, Xu L. Role of cancer ratio and other new parameters in the differential diagnosis of malignant pleural effusion. Clinics. 2021;76:e2515.","journal-title":"Clinics"},{"issue":"2","key":"4404_CR24","doi-asserted-by":"publisher","first-page":"133","DOI":"10.5578\/tt.20219802","volume":"69","author":"A Emin","year":"2021","unstructured":"Emin A. Can LENT Prognostic score (LDH, ECOG performance score, blood neutrophil\/lymphocyte ratio, tumor type) change the clinical approach in malignant pleural effusion? Tuberk Toraks. 2021;69(2):133\u201343.","journal-title":"Tuberk Toraks"},{"issue":"7","key":"4404_CR25","doi-asserted-by":"publisher","first-page":"853","DOI":"10.1016\/S1470-2045(18)30361-9","volume":"19","author":"P Baas","year":"2018","unstructured":"Baas P, Burgers S. Malignant pleural effusions: will PROMISE make its name true? Lancet Oncol. 2018;19(7):853\u20135.","journal-title":"Lancet Oncol"},{"issue":"4","key":"4404_CR26","doi-asserted-by":"publisher","first-page":"325","DOI":"10.4103\/lungindia.lungindia_633_21","volume":"39","author":"S Ermin","year":"2022","unstructured":"Ermin S, Ozdogan Y, Batum O, Yilmaz U. The role of LENT and PROMISE scores in predicting survival in malignant pleural effusion. Lung India. 2022;39(4):325\u201330.","journal-title":"Lung India"},{"issue":"8","key":"4404_CR27","doi-asserted-by":"publisher","first-page":"2885","DOI":"10.1007\/s13304-024-01985-2","volume":"76","author":"M Ayik Turk","year":"2024","unstructured":"Ayik Turk M, Polat G, Ozdemir O, Turk Y, Komurcuoglu B. Comparison of five scores to predict mortality in malignant pleural effusion. Updates Surg. 2024;76(8):2885\u201392.","journal-title":"Updates Surg"},{"issue":"2","key":"4404_CR28","doi-asserted-by":"publisher","first-page":"396","DOI":"10.3349\/ymj.2013.54.2.396","volume":"54","author":"DS Park","year":"2013","unstructured":"Park DS, Kim D, Hwang KE, Hwang YR, Park C, Seol CH, et al. Diagnostic value and prognostic significance of pleural C-reactive protein in lung cancer patients with malignant pleural effusions. Yonsei Med J. 2013;54(2):396\u2013402.","journal-title":"Yonsei Med J"},{"key":"4404_CR29","doi-asserted-by":"publisher","first-page":"29","DOI":"10.1186\/s12890-015-0025-z","volume":"15","author":"MM Zamboni","year":"2015","unstructured":"Zamboni MM, da Silva Jr CT, Baretta R, Cunha ET, Cardoso GP. Important prognostic factors for survival in patients with malignant pleural effusion. BMC Pulm Med. 2015;15:29.","journal-title":"BMC Pulm Med"},{"issue":"4","key":"4404_CR30","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0250628","volume":"16","author":"N Popowicz","year":"2021","unstructured":"Popowicz N, Cheah HM, Gregory C, Miranda A, Dick IM, Lee YCG, et al. Neutrophil-to-lymphocyte ratio in malignant pleural fluid: prognostic significance. PLoS ONE. 2021;16(4):e0250628.","journal-title":"PLoS ONE"}],"container-title":["Clinical and Translational Oncology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12094-026-04404-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s12094-026-04404-7","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12094-026-04404-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,24]],"date-time":"2026-10-24T01:02:12Z","timestamp":1792803732000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s12094-026-04404-7"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,5,22]]},"references-count":30,"journal-issue":{"issue":"11","published-online":{"date-parts":[[2026,11]]}},"alternative-id":["4404"],"URL":"https:\/\/doi.org\/10.1007\/s12094-026-04404-7","relation":{},"ISSN":["1699-3055"],"issn-type":[{"value":"1699-3055","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,5,22]]},"assertion":[{"value":"16 March 2026","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"6 May 2026","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"22 May 2026","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"There are no conflicts of interest.","order":1,"name":"Ethics","label":"Conflict of interest","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Human ethics and consent to participate declarations: Not applicable.","order":2,"name":"Ethics","label":"Consent to participate","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Not applicable.","order":3,"name":"Ethics","label":"Clinical trial number","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"None.","order":4,"name":"Ethics","label":"Previous presentation of data at meetings or in abstract form","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The study was initiated after the ethics committee approval from S\u00fcleyman Demirel University Health Sciences Ethics Committee (Date: 05.12.2023, No: 15\/255).","order":5,"name":"Ethics","label":"Ethics committee approval","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Not applicable.","order":6,"name":"Ethics","label":"Human and animal rights statements","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Signed consent was obtained for the use and publication of the patient\u2019s data.","order":7,"name":"Ethics","label":"Written consent for publication","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Not applicable.","order":8,"name":"Ethics","label":"Human and animal rights statements","group":{"name":"EthicsHeading","label":"Declarations"}}]}}