{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,27]],"date-time":"2026-10-27T20:39:34Z","timestamp":1793133574867,"version":"4.5.0"},"reference-count":45,"publisher":"Springer Science and Business Media LLC","issue":"12","license":[{"start":{"date-parts":[[2010,9,8]],"date-time":"2010-09-08T00:00:00Z","timestamp":1283904000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2010,9,8]],"date-time":"2010-09-08T00:00:00Z","timestamp":1283904000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Indian J Pediatr"],"published-print":{"date-parts":[[2010,12]]},"DOI":"10.1007\/s12098-010-0189-8","type":"journal-article","created":{"date-parts":[[2010,9,7]],"date-time":"2010-09-07T07:47:47Z","timestamp":1283845667000},"page":"1417-1423","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Management of Status Asthmaticus in Children"],"prefix":"10.1007","volume":"77","author":[{"given":"Sunil","family":"Saharan","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rakesh","family":"Lodha","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sushil K.","family":"Kabra","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2010,9,8]]},"reference":[{"key":"189_CR1","doi-asserted-by":"publisher","first-page":"469","DOI":"10.1111\/j.1398-9995.2004.00526.x","volume":"59","author":"M Masoli","year":"2004","unstructured":"Masoli M, Fabian D, Holt S, Beasley R, Global Initiative for Asthma (GINA) Program. The global burden of asthma: executive summary of the GINA Dissemination Committee report. Allergy 2004;59:469\u201378.","journal-title":"Allergy"},{"key":"189_CR2","doi-asserted-by":"publisher","first-page":"733","DOI":"10.1016\/S0140-6736(06)69283-0","volume":"368","author":"MI Asher","year":"2006","unstructured":"Asher MI, Montefort S, Bjorksten B, et al. Worldwide time trends in the prevalence of symptoms of asthma, allergic rhinoconjunctivitis, and eczema in childhood: ISAAC Phases One and Three repeat multicountry cross-sectional surveys. Lancet 2006;368:733\u201343.","journal-title":"Lancet"},{"key":"189_CR3","doi-asserted-by":"publisher","first-page":"193","DOI":"10.1111\/j.1365-2222.2008.03157.x","volume":"39","author":"RH Dougherty","year":"2009","unstructured":"Dougherty RH, Fahy JV. Acute exacerbations of asthma: epidemiology, biology and the exacerbation-prone phenotype. Clin Exp Allergy. 2009;39:193\u2013202.","journal-title":"Clin Exp Allergy"},{"key":"189_CR4","doi-asserted-by":"publisher","first-page":"385","DOI":"10.1385\/CRIAI:20:3:385","volume":"20","author":"M Afzal","year":"2001","unstructured":"Afzal M, Tharratt RS. Mechanical ventilation in severe asthma. Clin Rev Allergy Immunol. 2001;20:385\u201397.","journal-title":"Clin Rev Allergy Immunol"},{"key":"189_CR5","doi-asserted-by":"publisher","first-page":"23","DOI":"10.1111\/j.1398-9995.2005.00632.x","volume":"60","author":"I Tillie-Leblond","year":"2005","unstructured":"Tillie-Leblond I, Gosset P, Tonnel AB. Inflammatory events in severe acute asthma. Allergy 2005;60:23\u20139.","journal-title":"Allergy"},{"key":"189_CR6","doi-asserted-by":"crossref","first-page":"694","DOI":"10.1183\/09031936.98.11030694","volume":"11","author":"R Newson","year":"1998","unstructured":"Newson R, Strachan D, Archibald E, Emberlin J, Hardaker P, Collier C. Acute asthma epidemics, weather and pollen in England, 1987\u20131994. Eur Respir J. 1998;11:694\u2013701.","journal-title":"Eur Respir J"},{"key":"189_CR7","doi-asserted-by":"publisher","first-page":"1178","DOI":"10.1016\/j.jaci.2010.04.021","volume":"125","author":"DJ Jackson","year":"2010","unstructured":"Jackson DJ, Johnston SL. The role of viruses in acute exacerbations of asthma. J Allergy Clin Immunol. 2010;125:1178\u201387. quiz 1188\u20139.","journal-title":"J Allergy Clin Immunol"},{"key":"189_CR8","doi-asserted-by":"publisher","first-page":"1005","DOI":"10.1016\/0002-9343(83)90802-1","volume":"74","author":"BE Brenner","year":"1983","unstructured":"Brenner BE, Abraham E, Simon RR. Position and diaphoresis in acute asthma. Am J Med. 1983;74:1005\u20139.","journal-title":"Am J Med"},{"key":"189_CR9","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1152\/jappl.1972.32.3.391","volume":"32","author":"RN Pierson Jr","year":"1972","unstructured":"Pierson Jr RN, Grieco MH. Pulmonary blood volume in asthma. J Appl Physiol. 1972;32:391\u20136.","journal-title":"J Appl Physiol"},{"key":"189_CR10","doi-asserted-by":"crossref","first-page":"914","DOI":"10.1001\/archpedi.1996.02170340028005","volume":"150","author":"RO Wright","year":"1996","unstructured":"Wright RO, Steele DW, Santucci KA, Natarajan R, Jay GD. Continuous, noninvasive measurement of pulsus paradoxus in patients with acute asthma. Arch Pediatr Adolesc Med. 1996;150:914\u20138.","journal-title":"Arch Pediatr Adolesc Med"},{"key":"189_CR11","doi-asserted-by":"crossref","first-page":"574","DOI":"10.1001\/archpedi.1984.02140440058015","volume":"138","author":"AB Becker","year":"1984","unstructured":"Becker AB, Nelson NA, Simons FE. The pulmonary index. Assessment of a clinical score for asthma. Am J Dis Child. 1984;138:574\u20136.","journal-title":"Am J Dis Child"},{"key":"189_CR12","doi-asserted-by":"publisher","first-page":"1236","DOI":"10.1016\/S0196-0644(94)70347-7","volume":"23","author":"GC Geelhoed","year":"1994","unstructured":"Geelhoed GC, Landau LI, Le Souef PN. Evaluation of SaO2 as a predictor of outcome in 280 children presenting with acute asthma. Ann Emerg Med. 1994;23:1236\u201341.","journal-title":"Ann Emerg Med"},{"key":"189_CR13","doi-asserted-by":"publisher","first-page":"2043","DOI":"10.1001\/jama.249.15.2043","volume":"249","author":"RM Nowak","year":"1983","unstructured":"Nowak RM, Tomlanovich MC, Sarkar DD, Kvale PA, Anderson JA. Arterial blood gases and pulmonary function testing in acute bronchial asthma. Predicting patient outcomes. JAMA 1983;249:2043\u20136.","journal-title":"JAMA"},{"key":"189_CR14","doi-asserted-by":"publisher","first-page":"161","DOI":"10.1146\/annurev.med.47.1.161","volume":"47","author":"JM FitzGerald","year":"1996","unstructured":"FitzGerald JM, Macklem P. Fatal asthma. Annu Rev Med. 1996;47:161\u20138.","journal-title":"Annu Rev Med"},{"key":"189_CR15","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1136\/bmj.312.7023.79","volume":"312","author":"KS Joseph","year":"1996","unstructured":"Joseph KS, Blais L, Ernst P, Suissa S. Increased morbidity and mortality related to asthma among asthmatic patients who use major tranquillisers. BMJ 1996;312:79\u201382.","journal-title":"BMJ"},{"key":"189_CR16","doi-asserted-by":"publisher","first-page":"1312","DOI":"10.1378\/chest.124.4.1312","volume":"124","author":"GJ Rodrigo","year":"2003","unstructured":"Rodrigo GJ, Rodriquez Verde M, Peregalli V, Rodrigo C. Effects of short-term 28% and 100% oxygen on PaCO2 and peak expiratory flow rate in acute asthma: a randomized trial. Chest 2003;124:1312\u20137.","journal-title":"Chest"},{"key":"189_CR17","doi-asserted-by":"publisher","first-page":"29","DOI":"10.1016\/j.annemergmed.2005.02.001","volume":"46","author":"F Qureshi","year":"2005","unstructured":"Qureshi F, Zaritsky A, Welch C, Meadows T, Burke BL. Clinical efficacy of racemic albuterol versus levalbuterol for the treatment of acute pediatric asthma. Ann Emerg Med. 2005;46:29\u201336.","journal-title":"Ann Emerg Med"},{"key":"189_CR18","doi-asserted-by":"publisher","first-page":"1101","DOI":"10.1016\/0091-6749(88)90876-7","volume":"81","author":"FW Moler","year":"1988","unstructured":"Moler FW, Hurwitz ME, Custer JR. Improvement in clinical asthma score and PaCO2 in children with severe asthma treated with continuously nebulized terbutaline. J Allergy Clin Immunol. 1988;81:1101\u20139.","journal-title":"J Allergy Clin Immunol"},{"key":"189_CR19","doi-asserted-by":"publisher","first-page":"201","DOI":"10.3109\/02770909409044827","volume":"31","author":"VL Montgomery","year":"1994","unstructured":"Montgomery VL, Eid NS. Low-dose beta-agonist continuous nebulization therapy for status asthmaticus in children. J Asthma. 1994;31:201\u20137.","journal-title":"J Asthma"},{"key":"189_CR20","doi-asserted-by":"publisher","first-page":"1479","DOI":"10.1097\/00003246-199310000-00015","volume":"21","author":"MC Papo","year":"1993","unstructured":"Papo MC, Frank J, Thompson AE. A prospective, randomized study of continuous versus intermittent nebulized albuterol for severe status asthmaticus in children. Crit Care Med. 1993;21:1479\u201386.","journal-title":"Crit Care Med"},{"key":"189_CR21","doi-asserted-by":"publisher","first-page":"172","DOI":"10.1016\/j.jpeds.2004.04.007","volume":"145","author":"JA Castro-Rodriguez","year":"2004","unstructured":"Castro-Rodriguez JA, Rodrigo GJ. Beta-agonists through metered-dose inhaler with valved holding chamber versus nebulizer for acute exacerbation of wheezing or asthma in children under 5\u00a0years of age: a systematic review with meta-analysis. J Pediatr. 2004;145:172\u20137.","journal-title":"J Pediatr"},{"key":"189_CR22","doi-asserted-by":"crossref","unstructured":"Travers A, Jones AP, Kelly K, Barker SJ, Camargo CA, Rowe BH. Intravenous beta2-agonists for acute asthma in the emergency department. Cochrane Database Syst Rev. 2001; (2): CD002988.","DOI":"10.1002\/14651858.CD002988"},{"key":"189_CR23","doi-asserted-by":"publisher","first-page":"73","DOI":"10.1067\/mpd.2000.106567","volume":"137","author":"VW Chiang","year":"2000","unstructured":"Chiang VW, Burns JP, Rifai N, Lipshultz SE, Adams MJ, Weiner DL. Cardiac toxicity of intravenous terbutaline for the treatment of severe asthma in children: a prospective assessment. J Pediatr. 2000;137:73\u20137.","journal-title":"J Pediatr"},{"key":"189_CR24","doi-asserted-by":"publisher","first-page":"740","DOI":"10.1136\/thx.2005.047803","volume":"60","author":"GJ Rodrigo","year":"2005","unstructured":"Rodrigo GJ, Castro-Rodriguez JA. Anticholinergics in the treatment of children and adults with acute asthma: a systematic review with meta-analysis. Thorax 2005;60:740\u20136.","journal-title":"Thorax"},{"key":"189_CR25","doi-asserted-by":"publisher","first-page":"1480","DOI":"10.1378\/chest.119.5.1480","volume":"119","author":"RS Ream","year":"2001","unstructured":"Ream RS, Loftis LL, Albers GM, Becker BA, Lynch RE, Mink RB. Efficacy of IV theophylline in children with severe status asthmaticus. Chest 2001;119:1480\u20138.","journal-title":"Chest"},{"key":"189_CR26","doi-asserted-by":"crossref","unstructured":"Rowe BH, Spooner C, Ducharme FM, Bretzlaff JA, Bota GW. Early emergency department treatment of acute asthma with systemic corticosteroids. Cochrane Database Syst Rev. 2001; (1): CD002178.","DOI":"10.1002\/14651858.CD002178"},{"key":"189_CR27","doi-asserted-by":"publisher","first-page":"835","DOI":"10.1111\/j.1651-2227.1999.tb00057.x","volume":"88","author":"S Devidayal","year":"1999","unstructured":"Devidayal, Singhi S, Kumar L, Jayshree M. Efficacy of nebulized budesonide compared to oral prednisolone in acute bronchial asthma. Acta Paediatr. 1999;88:835\u201340.","journal-title":"Acta Paediatr"},{"key":"189_CR28","doi-asserted-by":"publisher","first-page":"480","DOI":"10.1016\/S0196-0644(95)70118-4","volume":"26","author":"RJ Scarfone","year":"1995","unstructured":"Scarfone RJ, Loiselle JM, Wiley 2nd JF, Decker JM, Henretig FM, Joffe MD. Nebulized dexamethasone versus oral prednisone in the emergency treatment of asthmatic children. Ann Emerg Med. 1995;26:480\u20136.","journal-title":"Ann Emerg Med"},{"key":"189_CR29","doi-asserted-by":"publisher","first-page":"689","DOI":"10.1056\/NEJM200009073431003","volume":"343","author":"S Schuh","year":"2000","unstructured":"Schuh S, Reisman J, Alshehri M, et al. A comparison of inhaled fluticasone and oral prednisone for children with severe acute asthma. N Engl J Med. 2000;343:689\u201394.","journal-title":"N Engl J Med"},{"key":"189_CR30","first-page":"1995","volume":"25","author":"MS Klein-Gitelman","year":"1998","unstructured":"Klein-Gitelman MS, Pachman LM. Intravenous corticosteroids: adverse reactions are more variable than expected in children. J Rheumatol. 1998;25:1995\u20132002.","journal-title":"J Rheumatol"},{"key":"189_CR31","doi-asserted-by":"publisher","first-page":"74","DOI":"10.1136\/adc.2004.050005","volume":"90","author":"DK Cheuk","year":"2005","unstructured":"Cheuk DK, Chau TC, Lee SL. A meta-analysis on intravenous magnesium sulphate for treating acute asthma. Arch Dis Child. 2005;90:74\u20137.","journal-title":"Arch Dis Child"},{"key":"189_CR32","doi-asserted-by":"publisher","first-page":"333","DOI":"10.1016\/j.jpeds.2003.12.018","volume":"144","author":"CJ Newth","year":"2004","unstructured":"Newth CJ, Rachman B, Patel N, Hammer J. The use of cuffed versus uncuffed endotracheal tubes in pediatric intensive care. J Pediatr. 2004;144:333\u20137.","journal-title":"J Pediatr"},{"key":"189_CR33","doi-asserted-by":"publisher","first-page":"379","DOI":"10.1097\/00003246-199603000-00003","volume":"24","author":"TE Stewart","year":"1996","unstructured":"Stewart TE, Slutsky AS. Occult, occult auto-PEEP in status asthmaticus. Crit Care Med. 1996;24:379\u201380.","journal-title":"Crit Care Med"},{"key":"189_CR34","doi-asserted-by":"publisher","first-page":"1913","DOI":"10.1378\/chest.119.6.1913","volume":"119","author":"HA Werner","year":"2001","unstructured":"Werner HA. Status asthmaticus in children: a review. Chest 2001;119:1913\u201329.","journal-title":"Chest"},{"key":"189_CR35","doi-asserted-by":"publisher","first-page":"972","DOI":"10.1007\/BF02044126","volume":"22","author":"MZ Youssef-Ahmed","year":"1996","unstructured":"Youssef-Ahmed MZ, Silver P, Nimkoff L, Sagy M. Continuous infusion of ketamine in mechanically ventilated children with refractory bronchospasm. Intensive Care Med. 1996;22:972\u20136.","journal-title":"Intensive Care Med"},{"key":"189_CR36","doi-asserted-by":"publisher","first-page":"395","DOI":"10.1136\/adc.78.4.395a","volume":"78","author":"M Rice","year":"1998","unstructured":"Rice M, Hatherill M, Murdoch IA. Rapid response to isoflurane in refractory status asthmaticus. Arch Dis Child. 1998;78:395\u20136.","journal-title":"Arch Dis Child"},{"key":"189_CR37","doi-asserted-by":"publisher","first-page":"34","DOI":"10.1111\/j.1365-2044.2006.04897.x","volume":"62","author":"CL Colebourn","year":"2007","unstructured":"Colebourn CL, Barber V, Young JD. Use of helium-oxygen mixture in adult patients presenting with exacerbations of asthma and chronic obstructive pulmonary disease: a systematic review. Anaesthesia 2007;62:34\u201342.","journal-title":"Anaesthesia"},{"key":"189_CR38","doi-asserted-by":"publisher","first-page":"1127","DOI":"10.1542\/peds.2004-2136","volume":"116","author":"IK Kim","year":"2005","unstructured":"Kim IK, Phrampus E, Venkataraman S, et al. Helium\/oxygen-driven albuterol nebulization in the treatment of children with moderate to severe asthma exacerbations: a randomized, controlled trial. Pediatrics 2005;116:1127\u201333.","journal-title":"Pediatrics"},{"key":"189_CR39","doi-asserted-by":"crossref","unstructured":"Rodrigo G, Pollack C, Rodrigo C, Rowe BH. Heliox for nonintubated acute asthma patients. Cochrane Database Syst Rev. 2006; (4): CD002884.","DOI":"10.1002\/14651858.CD002884.pub2"},{"key":"189_CR40","doi-asserted-by":"publisher","first-page":"891","DOI":"10.1378\/chest.123.3.891","volume":"123","author":"GJ Rodrigo","year":"2003","unstructured":"Rodrigo GJ, Rodrigo C, Pollack CV, Rowe B. Use of helium-oxygen mixtures in the treatment of acute asthma: a systematic review. Chest 2003;123:891\u20136.","journal-title":"Chest"},{"key":"189_CR41","doi-asserted-by":"publisher","first-page":"1256","DOI":"10.1378\/chest.109.5.1256","volume":"109","author":"ER Carter","year":"1996","unstructured":"Carter ER, Webb CR, Moffitt DR. Evaluation of heliox in children hospitalized with acute severe asthma. A randomized crossover trial. Chest 1996;109:1256\u201361.","journal-title":"Chest"},{"key":"189_CR42","doi-asserted-by":"publisher","first-page":"1480","DOI":"10.1378\/chest.126.5.1480","volume":"126","author":"RA Silverman","year":"2004","unstructured":"Silverman RA, Nowak RM, Korenblat PE, et al. Zafirlukast treatment for acute asthma: evaluation in a randomized, double-blind, multicenter trial. Chest 2004;126:1480\u20139.","journal-title":"Chest"},{"key":"189_CR43","doi-asserted-by":"publisher","first-page":"540","DOI":"10.1136\/adc.2009.168567","volume":"95","author":"VK Todi","year":"2010","unstructured":"Todi VK, Lodha R, Kabra SK. Effect of addition of single dose of oral montelukast to standard treatment in acute moderate to severe asthma in children between 5 and 15\u00a0years of age: a randomised, double-blind, placebo controlled trial. Arch Dis Child. 2010;95:540\u20133.","journal-title":"Arch Dis Child"},{"key":"189_CR44","doi-asserted-by":"publisher","first-page":"337","DOI":"10.1097\/01.PCC.0000128670.36435.83","volume":"5","author":"PJ Thill","year":"2004","unstructured":"Thill PJ, McGuire JK, Baden HP, Green TP, Checchia PA. Noninvasive positive-pressure ventilation in children with lower airway obstruction. Pediatr Crit Care Med. 2004;5:337\u201342.","journal-title":"Pediatr Crit Care Med"},{"key":"189_CR45","doi-asserted-by":"publisher","first-page":"454","DOI":"10.1016\/S1081-1206(10)60913-1","volume":"96","author":"CL Carroll","year":"2006","unstructured":"Carroll CL, Schramm CM. Noninvasive positive pressure ventilation for the treatment of status asthmaticus in children. Ann Allergy Asthma Immunol. 2006;96:454\u20139.","journal-title":"Ann Allergy Asthma Immunol"}],"container-title":["The Indian Journal of Pediatrics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12098-010-0189-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s12098-010-0189-8\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s12098-010-0189-8","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12098-010-0189-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,9]],"date-time":"2025-04-09T03:37:51Z","timestamp":1744169871000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s12098-010-0189-8"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,9,8]]},"references-count":45,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2010,12]]}},"alternative-id":["189"],"URL":"https:\/\/doi.org\/10.1007\/s12098-010-0189-8","relation":{},"ISSN":["0019-5456","0973-7693"],"issn-type":[{"value":"0019-5456","type":"print"},{"value":"0973-7693","type":"electronic"}],"subject":[],"published":{"date-parts":[[2010,9,8]]},"assertion":[{"value":"21 July 2010","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"18 August 2010","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"8 September 2010","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}}]}}