{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T18:33:27Z","timestamp":1788287607832,"version":"build-2803163510"},"reference-count":16,"publisher":"Springer Science and Business Media LLC","issue":"12","license":[{"start":{"date-parts":[[2014,5,14]],"date-time":"2014-05-14T00:00:00Z","timestamp":1400025600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Indian J Pediatr"],"published-print":{"date-parts":[[2014,12]]},"DOI":"10.1007\/s12098-014-1389-4","type":"journal-article","created":{"date-parts":[[2014,5,12]],"date-time":"2014-05-12T21:40:29Z","timestamp":1399930829000},"page":"1302-1306","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["Co-morbidities Leading to Mortality or Hospitalization in Children with Down Syndrome and its Effect on the Quality of Life of their Parents"],"prefix":"10.1007","volume":"81","author":[{"given":"Seema","family":"Kapoor","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Swati","family":"Bhayana","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ankur","family":"Singh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jugal","family":"Kishore","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2014,5,14]]},"reference":[{"key":"1389_CR1","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1007\/BF02724426","volume":"72","author":"ZM Patel","year":"2005","unstructured":"Patel ZM, Adhia RA. Birth defects surveillance study. Indian J Pediatr. 2005;72:489\u201391.","journal-title":"Indian J Pediatr"},{"key":"1389_CR2","doi-asserted-by":"crossref","unstructured":"Verma IC. Genetic causes of mental retardation in India. In: Hicks EK, Berg JM, eds. The Genetics of Mental Retardation. Dordrecht: Kluwer Academic Publishers; 1988. pp. 99\u2013106.","DOI":"10.1007\/978-94-009-1339-4_12"},{"key":"1389_CR3","doi-asserted-by":"crossref","unstructured":"Kava MP, Tullu MS, Muranjan MN, Girisha KM. Down syndrome: Clinical profile from India. Arch Med Res. 2004;35:31\u20135","DOI":"10.1016\/j.arcmed.2003.06.005"},{"key":"1389_CR4","doi-asserted-by":"crossref","first-page":"625","DOI":"10.1111\/j.1365-2214.2007.00742.x","volume":"33","author":"N Horwitz","year":"2007","unstructured":"Horwitz N, Ellis J. Paediatric SpRs\u2019 experiences of breaking bad news. Child Care Health Dev. 2007;33:625\u201330.","journal-title":"Child Care Health Dev"},{"key":"1389_CR5","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1046\/j.1365-3016.2000.00252.x","volume":"14","author":"S Leonard","year":"2000","unstructured":"Leonard S, Bower C, Petterson B, Leonard H. Survival of infants born with Down\u2019s syndrome: 1980\u201396. Paediatr Perinat Epidemiol. 2000;14:163\u201371.","journal-title":"Paediatr Perinat Epidemiol."},{"key":"1389_CR6","doi-asserted-by":"crossref","first-page":"218","DOI":"10.1002\/uog.1979","volume":"26","author":"F Prefumo","year":"2005","unstructured":"Prefumo F, Ierullo AM, Fulcheri E, Venturini PL, De Biasio P, Thilaganathan B. A newly described thoracic vascular malformation in fetuses with Down syndrome. Ultrasound Obstet Gynecol. 2005;26:218\u201320.","journal-title":"Ultrasound Obstet Gynecol"},{"key":"1389_CR7","doi-asserted-by":"crossref","first-page":"442","DOI":"10.1542\/peds.107.2.442","volume":"107","author":"American Academy of Pediatrics, Committee on Genetics","year":"2001","unstructured":"American Academy of Pediatrics, Committee on Genetics. American Academy of Pediatrics: Health supervision for children with Down syndrome. Pediatrics. 2001;107:442\u20139.","journal-title":"Pediatrics"},{"key":"1389_CR8","doi-asserted-by":"crossref","first-page":"440","DOI":"10.5152\/akd.2010.143","volume":"10","author":"E Mihci","year":"2010","unstructured":"Mihci E, Akcurin G, Eren E, Kardelen F, Akcurin S, Keser I, et al. Evaluation of congenital heart disease and thyroid abnormalities in children with Down syndrome. Anadolu Kardiyol Derg. 2010;10:440\u20135.","journal-title":"Anadolu Kardiyol Derg."},{"key":"1389_CR9","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1111\/jar.12023","volume":"26","author":"N Miodrag","year":"2013","unstructured":"Miodrag N, Silverberg SE, Urbano RC, Hodapp RM. Deaths among children, adolescents, and young adults with down syndrome. J Appl Res Intellect Disabil. 2013;26:207\u201314.","journal-title":"J Appl Res Intellect Disabil"},{"key":"1389_CR10","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1111\/j.1365-2249.2011.04335.x","volume":"164","author":"G Ram","year":"2011","unstructured":"Ram G, Chinen J. Infections and immunodeficiency in Down syndrome. Clin Exp Immunol. 2011;164:9\u201316.","journal-title":"Clin Exp Immunol"},{"key":"1389_CR11","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1111\/j.1365-2788.1994.tb00370.x","volume":"38","author":"F Licastro","year":"1994","unstructured":"Licastro F, Chiricolo M, Mocchegiani E, Fabris N, Zannoti M, Beltrandi E, et al. Oral zinc supplementation in Down\u2019s syndrome subjects decreased infections and normalized some humoral and cellular immune parameters. J Intellect Disabil Res. 1994;38:149\u201362.","journal-title":"J Intellect Disabil Res"},{"key":"1389_CR12","doi-asserted-by":"crossref","first-page":"806","DOI":"10.1016\/j.jpeds.2006.01.010","volume":"148","author":"SA Rasmussen","year":"2006","unstructured":"Rasmussen SA, Wong LY, Correa A, Gambrell D, Friedman JM. Survival in infants with Down syndrome, Metropolitan Atlanta, 1979-1998. J Pediatr. 2006;148:806\u201312.","journal-title":"J Pediatr"},{"key":"1389_CR13","doi-asserted-by":"crossref","first-page":"234","DOI":"10.1046\/j.1365-2788.1999.00198.x","volume":"43","author":"C Frid","year":"1999","unstructured":"Frid C, Drott P, Lundell B, Rasmussen F, Anneren G. Mortality in Down\u2019s syndrome in relation to congenital malformation. J Intellect Disabil Res. 1999;43:234\u201341.","journal-title":"J Intellect Disabil Res"},{"key":"1389_CR14","first-page":"997","volume":"28","author":"P Lakshminarayana","year":"1991","unstructured":"Lakshminarayana P, Ibrahim S, Venkataraman P, Jagatheesan T, Kamala KG. KAP study on mothers of children with Down syndrome. Indian Pediatr. 1991;28:997\u20131001.","journal-title":"Indian Pediatr"},{"key":"1389_CR15","doi-asserted-by":"crossref","first-page":"2349","DOI":"10.1111\/j.1365-2702.2007.02013.x","volume":"16","author":"MY Chang","year":"2007","unstructured":"Chang MY, Hsu LL. The perceptions of Taiwanese families who have children with learning disability. J Clin Nurs. 2007;16:2349\u201356.","journal-title":"J Clin Nurs"},{"key":"1389_CR16","author":"CY Hsiao","year":"2013","unstructured":"Hsiao CY. Family demands, social support and family functioning in Taiwanese families rearing children with Down syndrome. J Intellect Disabil Res. 2013. doi: 10.1111\/jir.12052 .","journal-title":"J Intellect Disabil Res"}],"container-title":["The Indian Journal of Pediatrics"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s12098-014-1389-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s12098-014-1389-4\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s12098-014-1389-4","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,6,1]],"date-time":"2019-06-01T23:59:15Z","timestamp":1559433555000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s12098-014-1389-4"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,5,14]]},"references-count":16,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2014,12]]}},"alternative-id":["1389"],"URL":"https:\/\/doi.org\/10.1007\/s12098-014-1389-4","relation":{},"ISSN":["0019-5456","0973-7693"],"issn-type":[{"value":"0019-5456","type":"print"},{"value":"0973-7693","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,5,14]]}}}