{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,22]],"date-time":"2026-01-22T21:07:48Z","timestamp":1769116068873,"version":"3.49.0"},"reference-count":24,"publisher":"Springer Science and Business Media LLC","issue":"4","license":[{"start":{"date-parts":[[2014,10,10]],"date-time":"2014-10-10T00:00:00Z","timestamp":1412899200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Indian J Pediatr"],"published-print":{"date-parts":[[2015,4]]},"DOI":"10.1007\/s12098-014-1584-3","type":"journal-article","created":{"date-parts":[[2014,10,9]],"date-time":"2014-10-09T02:14:18Z","timestamp":1412820858000},"page":"363-367","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":19,"title":["Role of Prophylactic Vitamin K in Preventing Antibiotic Induced Hypoprothrombinemia"],"prefix":"10.1007","volume":"82","author":[{"given":"Farookh","family":"Aziz","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Prashant","family":"Patil","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2014,10,10]]},"reference":[{"key":"1584_CR1","doi-asserted-by":"crossref","first-page":"628","DOI":"10.3181\/00379727-37-9668P","volume":"37","author":"ED Warner","year":"1939","unstructured":"Warner ED, Brinkhous KM, Smith HP. Bleeding tendency of obstructive jaundice: prothrombin deficiency and dietary factors. Proc Soc Exp Biol Med. 1939;37:628\u201330.","journal-title":"Proc Soc Exp Biol Med"},{"key":"1584_CR2","doi-asserted-by":"crossref","unstructured":"Waddell WW Jr, Guerry III DP, Bray WE, Kelley OR. Possible effects of vitamin K on prothrombin and clotting time in newly-born infants. Proc Soc Exp Biol Med. 1939;40:432\u20134.","DOI":"10.3181\/00379727-40-10443P"},{"key":"1584_CR3","doi-asserted-by":"crossref","first-page":"1162","DOI":"10.1016\/S0140-6736(00)58013-1","volume":"2","author":"R Kark","year":"1939","unstructured":"Kark R, Lozner EL. Nutritional deficiency of vitamin K in man. A study of four non-jaundiced patients with dietary deficiency. Lancet. 1939;2:1162\u20134.","journal-title":"Lancet"},{"key":"1584_CR4","doi-asserted-by":"crossref","first-page":"1157","DOI":"10.1016\/S0140-6736(00)58012-X","volume":"2","author":"H Dam","year":"1939","unstructured":"Dam H, Tage-Hansen E, Plum P. Vitamin-K lack in normal and sick infants. Lancet. 1939;2:1157\u201361.","journal-title":"Lancet"},{"key":"1584_CR5","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1016\/S0065-3101(22)00824-6","volume":"5","author":"H Dam","year":"1952","unstructured":"Dam H, Dyggve H, Larsen H, Plum P. The relation of vitamin K deficiency to hemorrhagic disease of the newborn. Adv Pediatr. 1952;5:129\u201353.","journal-title":"Adv Pediatr"},{"key":"1584_CR6","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1128\/AAC.31.2.281","volume":"31","author":"RL Nicholas","year":"1987","unstructured":"Nicholas RL, Wilker MA, Mcdevitt JT, Lentnek AL, Hosutt JA. Coagulopathy associated with extended spectrum cephalosporin in patients with serious infections. Antimicrob Agents Chemother. 1987;31:281\u20135.","journal-title":"Antimicrob Agents Chemother"},{"key":"1584_CR7","unstructured":"Kliegman RM, Stanton BF, Geme III JW, Schor NF, Behrman RE. Nelson textbook of paediatrics. 19th ed. New Delhi: Elsevier publication; 2011. p. 209\u201310. Chapter 50,vitamin K."},{"key":"1584_CR8","doi-asserted-by":"crossref","first-page":"2893","DOI":"10.1073\/pnas.81.9.2893","volume":"81","author":"JJ Lipsky","year":"1984","unstructured":"Lipsky JJ. Mechanism of the inhibition of the gamma carboxylation of glutamic acid by N-methylthiotetrazole containing antibiotics. Proc Natl Acad Sci U S A. 1984;81:2893\u20137.","journal-title":"Proc Natl Acad Sci U S A"},{"key":"1584_CR9","doi-asserted-by":"crossref","first-page":"857","DOI":"10.1128\/AAC.33.6.857","volume":"33","author":"LS Welage","year":"1989","unstructured":"Welage LS, Hejmanowski LG, Wilton JH, Walawander C, Rigan D, Williams JS, et al. Comparison of N-methylthiotetrazole disposition in healthy volunteers following single intravenous dosages of moxalactam, cefoperazone and cefotetan. Antimicrob Agents Chemother. 1989;33:857\u201361.","journal-title":"Antimicrob Agents Chemother"},{"key":"1584_CR10","doi-asserted-by":"crossref","first-page":"202","DOI":"10.1093\/infdis\/150.2.202","volume":"150","author":"JM Conly","year":"1984","unstructured":"Conly JM, Ramotar K, Chubb H, Bow EJ, Louie TJ. Hypoprothrombinemia in febrile neutropenic patients with cancer: association with antimicrobial suppression of intestinal microflora. J Infect Dis. 1984;150:202\u201312.","journal-title":"J Infect Dis"},{"key":"1584_CR11","unstructured":"Human vitamin and mineral requirements. Report of a joint FAO\/WHO expert consultation. Bangkok, Thailand: FAO\/WHO; 1998."},{"key":"1584_CR12","unstructured":"Nutreint reference values for Australia and New Zealand including recommended dietary intakes [internet]. NHMRC publications; 2006. Available from: http:\/\/www.nhmrc.gov.au\/guidelines\/publications\/n35-n36-n37 ."},{"key":"1584_CR13","unstructured":"Nathan DG, Orkin SH, Ginsburg D, Look AT. Hematology of infancy and childhood. 6th ed. Philadelphia: W.B. Saunders company; 2003. Appendices;p.1853"},{"key":"1584_CR14","unstructured":"Hypoprothrombinemia workup. [internet]. Available from: http:\/\/emedicine.medscape.com\/article\/956030-workup"},{"key":"1584_CR15","doi-asserted-by":"crossref","first-page":"316","DOI":"10.3181\/00379727-144-37581","volume":"144","author":"JT Matschiner","year":"1973","unstructured":"Matschiner JT, Bell RG. Effect of sex and sex hormones on plasmaprothrombin and vitamin K deficiency. Proc Soc Exp Biol Med. 1973;144:316\u201320.","journal-title":"Proc Soc Exp Biol Med"},{"key":"1584_CR16","first-page":"36","volume":"40","author":"RV Bhat","year":"2003","unstructured":"Bhat RV, Deshmukh CT. A study of Vitamin K status in children on prolonged antibiotic therapy. Indian Pediatr. 2003;40:36\u201340.","journal-title":"Indian Pediatr"},{"key":"1584_CR17","first-page":"11","volume":"47","author":"F Ehsanipour","year":"2002","unstructured":"Ehsanipour F, Zarifian D. Study of coagulopathy and its risk factors in children on prolonged antibiotic therapy admitted into Rasoul-e-Akram hospital. Razi J MedSci. 2002;47:11\u20137.","journal-title":"Razi J Med.Sci"},{"key":"1584_CR18","first-page":"880","volume":"109","author":"GF Pineo","year":"1973","unstructured":"Pineo GF, Gallus AS, Hirsh J. Unexpected vitamin K deficiency in hospitalized patients. Can Med Assoc J. 1973;109:880\u20133.","journal-title":"Can Med Assoc J"},{"key":"1584_CR19","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1002\/j.1552-4604.1988.tb03106.x","volume":"28","author":"MJ Shearer","year":"1988","unstructured":"Shearer MJ, Bechtold H, Andrassy K, Koderisch J, McCarthy PT, Trenk D, et al. Mechanism of cephalosporin-induced hypoprothrombinemia: relation to cephalosporin side chain, vitamin K metabolism, and vitamin K status. J Clin Pharmacol. 1988;28:88\u201395.","journal-title":"J Clin Pharmacol"},{"key":"1584_CR20","doi-asserted-by":"crossref","first-page":"738","DOI":"10.1136\/jcp.44.9.738","volume":"44","author":"KJ Williams","year":"1991","unstructured":"Williams KJ, Bax RP, Brown H, Machin SJ. Antibiotic treatment and associated prolonged prothrombin time. J Clin Pathol. 1991;44:738\u201341.","journal-title":"J Clin Pathol"},{"key":"1584_CR21","first-page":"1327","volume-title":"Hematology of infancy and childhood","author":"JM Lusher","year":"1987","unstructured":"Lusher JM. Diseases of coagulation. In: Nathan DG, Oski FA, editors. Hematology of infancy and childhood. 3rd ed. Philadelphia: W.B. Saunders Company; 1987. p. 1327\u20138.","edition":"3"},{"key":"1584_CR22","doi-asserted-by":"crossref","first-page":"846","DOI":"10.1093\/ajcn\/51.5.846","volume":"51","author":"Y Usui","year":"1990","unstructured":"Usui Y, Tanimura H, Nishimura N, Kobayashi N, Okanoue T, Ozawa K. Vitamin K concentration in the plasma and liver of surgical patients. Am J Clin Nutr. 1990;51:846\u201352.","journal-title":"Am J Clin Nutr"},{"key":"1584_CR23","first-page":"93","volume":"70","author":"P Barkhan","year":"1977","unstructured":"Barkhan P, Shearer MJ. Metabolism of vitamin K1 (phyloquinone) in man. Proc R Soc Med. 1977;70:93\u20136.","journal-title":"Proc R Soc Med"},{"key":"1584_CR24","doi-asserted-by":"crossref","first-page":"543","DOI":"10.1079\/BJN2002565","volume":"87","author":"RE Olson","year":"2002","unstructured":"Olson RE, Chao J, Graham D, Bates MW, Lewis JH. Total body phyloquinone and its turnover in human subjects at two levels of vitamin K intake. Br J Nutr. 2002;87:543\u201353.","journal-title":"Br J Nutr"}],"container-title":["The Indian Journal of Pediatrics"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s12098-014-1584-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s12098-014-1584-3\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s12098-014-1584-3","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,7,17]],"date-time":"2023-07-17T04:34:30Z","timestamp":1689568470000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s12098-014-1584-3"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,10,10]]},"references-count":24,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2015,4]]}},"alternative-id":["1584"],"URL":"https:\/\/doi.org\/10.1007\/s12098-014-1584-3","relation":{},"ISSN":["0019-5456","0973-7693"],"issn-type":[{"value":"0019-5456","type":"print"},{"value":"0973-7693","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,10,10]]}}}