{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T14:47:22Z","timestamp":1792594042076,"version":"4.5.0"},"reference-count":34,"publisher":"Springer Science and Business Media LLC","issue":"7","license":[{"start":{"date-parts":[[2015,3,26]],"date-time":"2015-03-26T00:00:00Z","timestamp":1427328000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Indian J Pediatr"],"published-print":{"date-parts":[[2015,7]]},"DOI":"10.1007\/s12098-015-1739-x","type":"journal-article","created":{"date-parts":[[2015,3,25]],"date-time":"2015-03-25T03:12:54Z","timestamp":1427253174000},"page":"637-641","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Stem Cell Therapy in Neonatal Diseases"],"prefix":"10.1007","volume":"82","author":[{"given":"Ciprian P.","family":"Gheorghe","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vineet","family":"Bhandari","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2015,3,26]]},"reference":[{"key":"1739_CR1","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1016\/j.stem.2007.05.013","volume":"1","author":"M Ramalho-Santos","year":"2007","unstructured":"Ramalho-Santos M, Willenbring H. On the origin of the term \u201cstem cell\u201d. Cell Stem Cell. 2007;1:35\u20138.","journal-title":"Cell Stem Cell"},{"key":"1739_CR2","doi-asserted-by":"crossref","first-page":"1145","DOI":"10.1126\/science.282.5391.1145","volume":"282","author":"JA Thomson","year":"1998","unstructured":"Thomson JA, Itskovitz-Eldor J, Shapiro SS, et al. Embryonic stem cell lines derived from human blastocysts. Science. 1998;282:1145\u20137.","journal-title":"Science"},{"key":"1739_CR3","doi-asserted-by":"crossref","first-page":"1917","DOI":"10.1126\/science.1151526","volume":"318","author":"J Yu","year":"2007","unstructured":"Yu J, Vodyanik MA, Smuga-Otto K, et al. Induced pluripotent stem cell lines derived from human somatic cells. Science. 2007;318:1917\u201320.","journal-title":"Science"},{"key":"1739_CR4","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1016\/S0065-230X(08)00005-5","volume":"100","author":"B Blum","year":"2008","unstructured":"Blum B, Benvenisty N. The tumorigenicity of human embryonic stem cells. Adv Cancer Res. 2008;100:133\u201358.","journal-title":"Adv Cancer Res"},{"key":"1739_CR5","doi-asserted-by":"crossref","first-page":"641","DOI":"10.1002\/jor.1100090504","volume":"9","author":"AI Caplan","year":"1991","unstructured":"Caplan AI. Mesenchymal stem cells. J Orthop Res. 1991;9:641\u201350.","journal-title":"J Orthop Res"},{"key":"1739_CR6","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1080\/14653240600855905","volume":"8","author":"M Dominici","year":"2006","unstructured":"Dominici M, Le Blanc K, Mueller I, et al. Minimal criteria for defining multipotent mesenchymal stromal cells. The International Society for Cellular Therapy position statement. Cytotherapy. 2006;8:315\u20137.","journal-title":"Cytotherapy"},{"key":"1739_CR7","doi-asserted-by":"crossref","first-page":"1283","DOI":"10.1080\/10428190701361869","volume":"48","author":"D Noel","year":"2007","unstructured":"Noel D, Djouad F, Bouffi C, Mrugala D, Jorgensen C. Multipotent mesenchymal stromal cells and immune tolerance. Leuk Lymphoma. 2007;48:1283\u20139.","journal-title":"Leuk Lymphoma"},{"key":"1739_CR8","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1203\/PDR.0b013e31817445e9","volume":"64","author":"MJ Javed","year":"2008","unstructured":"Javed MJ, Mead LE, Prater D, et al. Endothelial colony forming cells and mesenchymal stem cells are enriched at different gestational ages in human umbilical cord blood. Pediatr Res. 2008;64:68\u201373.","journal-title":"Pediatr Res"},{"key":"1739_CR9","doi-asserted-by":"crossref","first-page":"521","DOI":"10.1111\/j.1651-2227.2007.00194.x","volume":"96","author":"MJ Bizzarro","year":"2007","unstructured":"Bizzarro MJ, Bhandari V, Krause DS, Smith BR, Gross I. Circulating stem cells in extremely preterm neonates. Acta Paediatr. 2007;96:521\u20135.","journal-title":"Acta Paediatr"},{"key":"1739_CR10","doi-asserted-by":"crossref","first-page":"875","DOI":"10.1016\/S0301-472X(00)00482-3","volume":"28","author":"RJ Deans","year":"2000","unstructured":"Deans RJ, Moseley AB. Mesenchymal stem cells: biology and potential clinical uses. Exp Hematol. 2000;28:875\u201384.","journal-title":"Exp Hematol"},{"key":"1739_CR11","doi-asserted-by":"crossref","first-page":"e370","DOI":"10.2741\/1060","volume":"8","author":"A Bhandari","year":"2003","unstructured":"Bhandari A, Bhandari V. Pathogenesis, pathology and pathophysiology of pulmonary sequelae of bronchopulmonary dysplasia in premature infants. Front Biosci. 2003;8:e370\u201380.","journal-title":"Front Biosci"},{"key":"1739_CR12","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1053\/j.semperi.2013.01.010","volume":"37","author":"A Bhandari","year":"2013","unstructured":"Bhandari A, McGrath-Morrow S. Long-term pulmonary outcomes of patients with bronchopulmonary dysplasia. Semin Perinatol. 2013;37:132\u20137.","journal-title":"Semin Perinatol"},{"key":"1739_CR13","doi-asserted-by":"crossref","first-page":"L1073","DOI":"10.1152\/ajplung.00347.2006","volume":"292","author":"V Balasubramaniam","year":"2007","unstructured":"Balasubramaniam V, Mervis CF, Maxey AM, Markham NE, Abman SH. Hyperoxia reduces bone marrow, circulating, and lung endothelial progenitor cells in the developing lung: implications for the pathogenesis of bronchopulmonary dysplasia. Am J Physiol Lung Cell Mol Physiol. 2007;292:L1073\u201384.","journal-title":"Am J Physiol Lung Cell Mol Physiol"},{"key":"1739_CR14","doi-asserted-by":"crossref","first-page":"e1127","DOI":"10.1542\/peds.2009-3445","volume":"126","author":"AP Popova","year":"2010","unstructured":"Popova AP, Bozyk PD, Bentley JK, et al. Isolation of tracheal aspirate mesenchymal stromal cells predicts bronchopulmonary dysplasia. Pediatrics. 2010;126:e1127\u201333.","journal-title":"Pediatrics"},{"key":"1739_CR15","doi-asserted-by":"crossref","first-page":"1158","DOI":"10.1164\/rccm.200607-941OC","volume":"175","author":"KT Hennrick","year":"2007","unstructured":"Hennrick KT, Keeton AG, Nanua S, et al. Lung cells from neonates show a mesenchymal stem cell phenotype. Am J Respir Crit Care Med. 2007;175:1158\u201364.","journal-title":"Am J Respir Crit Care Med"},{"key":"1739_CR16","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1053\/j.semperi.2013.01.003","volume":"37","author":"M O\u2019Reilly","year":"2013","unstructured":"O\u2019Reilly M, Thebaud B. The promise of stem cells in bronchopulmonary dysplasia. Semin Perinatol. 2013;37:79\u201384.","journal-title":"Semin Perinatol"},{"key":"1739_CR17","first-page":"1692","volume":"27","author":"ZF Tian","year":"2007","unstructured":"Tian ZF, Du J, Wang B, Hong XY, Feng ZC. Intravenous infusion of rat bone marrow-derived mesenchymal stem cells ameliorates hyperoxia-induced lung injury in neonatal rats. Nan Fang Yi Ke Da Xue Xue Bao. 2007;27:1692\u20135.","journal-title":"Nan Fang Yi Ke Da Xue Xue Bao"},{"key":"1739_CR18","doi-asserted-by":"crossref","first-page":"589","DOI":"10.1042\/CBI20110447","volume":"36","author":"X Zhang","year":"2012","unstructured":"Zhang X, Wang H, Shi Y, et al. Role of bone marrow-derived mesenchymal stem cells in the prevention of hyperoxia-induced lung injury in newborn mice. Cell Biol Int. 2012;36:589\u201394.","journal-title":"Cell Biol Int"},{"key":"1739_CR19","doi-asserted-by":"crossref","first-page":"1122","DOI":"10.1164\/rccm.200902-0242OC","volume":"180","author":"M Aslam","year":"2009","unstructured":"Aslam M, Baveja R, Liang OD, et al. Bone marrow stromal cells attenuate lung injury in a murine model of neonatal chronic lung disease. Am J Respir Crit Care Med. 2009;180:1122\u201330.","journal-title":"Am J Respir Crit Care Med"},{"key":"1739_CR20","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1038\/pr.2013.176","volume":"75","author":"ME Fung","year":"2014","unstructured":"Fung ME, Thebaud B. Stem cell-based therapy for neonatal lung disease: it is in the juice. Pediatr Res. 2014;75:2\u20137.","journal-title":"Pediatr Res"},{"key":"1739_CR21","doi-asserted-by":"crossref","first-page":"3037","DOI":"10.1093\/ndt\/gfs168","volume":"27","author":"L Biancone","year":"2012","unstructured":"Biancone L, Bruno S, Deregibus MC, Tetta C, Camussi G. Therapeutic potential of mesenchymal stem cell-derived microvesicles. Nephrol Dial Transplant. 2012;27:3037\u201342.","journal-title":"Nephrol Dial Transplant"},{"key":"1739_CR22","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1016\/j.bcmd.2005.12.001","volume":"36","author":"RM Johnstone","year":"2006","unstructured":"Johnstone RM. Exosomes biological significance: a concise review. Blood Cells Mol Dis. 2006;36:315\u201321.","journal-title":"Blood Cells Mol Dis"},{"key":"1739_CR23","doi-asserted-by":"crossref","first-page":"966","DOI":"10.1016\/j.jpeds.2013.12.011","volume":"164","author":"YS Chang","year":"2014","unstructured":"Chang YS, Ahn SY, Yoo HS, et al. Mesenchymal stem cells for bronchopulmonary dysplasia: phase 1 dose-escalation clinical trial. J Pediatr. 2014;164:966\u201372.e6.","journal-title":"J Pediatr"},{"key":"1739_CR24","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1053\/j.sempedsurg.2014.04.004","volume":"23","author":"DO Fauza","year":"2014","unstructured":"Fauza DO. Tissue engineering in congenital diaphragmatic hernia. Semin Pediatr Surg. 2014;23:135\u201340.","journal-title":"Semin Pediatr Surg"},{"key":"1739_CR25","doi-asserted-by":"crossref","first-page":"907","DOI":"10.1007\/s00383-014-3576-9","volume":"30","author":"R Yuniartha","year":"2014","unstructured":"Yuniartha R, Alatas FS, Nagata K, et al. Therapeutic potential of mesenchymal stem cell transplantation in a nitrofen-induced congenital diaphragmatic hernia rat model. Pediatr Surg Int. 2014;30:907\u201314.","journal-title":"Pediatr Surg Int"},{"key":"1739_CR26","doi-asserted-by":"crossref","first-page":"589","DOI":"10.1002\/ana.22670","volume":"71","author":"L Bennet","year":"2012","unstructured":"Bennet L, Tan S, Van den Heuij L, et al. Cell therapy for neonatal hypoxia-ischemia and cerebral palsy. Ann Neurol. 2012;71:589\u2013600.","journal-title":"Ann Neurol"},{"key":"1739_CR27","doi-asserted-by":"crossref","first-page":"890","DOI":"10.1038\/bmt.2012.169","volume":"48","author":"Y Liao","year":"2013","unstructured":"Liao Y, Cotten M, Tan S, Kurtzberg J, Cairo MS. Rescuing the neonatal brain from hypoxic injury with autologous cord blood. Bone Marrow Transplant. 2013;48:890\u2013900.","journal-title":"Bone Marrow Transplant"},{"key":"1739_CR28","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1007\/s00381-013-2304-4","volume":"30","author":"L Chicha","year":"2014","unstructured":"Chicha L, Smith T, Guzman R. Stem cells for brain repair in neonatal hypoxia-ischemia. Childs Nerv Syst. 2014;30:37\u201346.","journal-title":"Childs Nerv Syst"},{"key":"1739_CR29","doi-asserted-by":"crossref","first-page":"810","DOI":"10.1016\/j.jcyt.2014.01.008","volume":"16","author":"C Mancias-Guerra","year":"2014","unstructured":"Mancias-Guerra C, Marroquin-Escamilla AR, Gonzalez-Llano O, et al. Safety and tolerability of intrathecal delivery of autologous bone marrow nucleated cells in children with cerebral palsy: an open-label phase I trial. Cytotherapy. 2014;16:810\u201320.","journal-title":"Cytotherapy"},{"key":"1739_CR30","doi-asserted-by":"crossref","first-page":"1549","DOI":"10.1016\/j.jcyt.2013.06.001","volume":"15","author":"X Wang","year":"2013","unstructured":"Wang X, Cheng H, Hua R, et al. Effects of bone marrow mesenchymal stromal cells on gross motor function measure scores of children with cerebral palsy: a preliminary clinical study. Cytotherapy. 2013;15:1549\u201362.","journal-title":"Cytotherapy"},{"key":"1739_CR31","doi-asserted-by":"crossref","first-page":"581","DOI":"10.1002\/stem.1304","volume":"31","author":"K Min","year":"2013","unstructured":"Min K, Song J, Kang JY, et al. Umbilical cord blood therapy potentiated with erythropoietin for children with cerebral palsy: a double-blind, randomized, placebo-controlled trial. Stem Cells. 2013;31:581\u201391.","journal-title":"Stem Cells"},{"key":"1739_CR32","doi-asserted-by":"crossref","first-page":"973","DOI":"10.1016\/j.jpeds.2013.11.036","volume":"164","author":"CM Cotten","year":"2014","unstructured":"Cotten CM, Murtha AP, Goldberg RN, et al. Feasibility of autologous cord blood cells for infants with hypoxic-ischemic encephalopathy. J Pediatr. 2014;164:973\u20139.e1.","journal-title":"J Pediatr"},{"key":"1739_CR33","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1203\/PDR.0b013e31822d7ef2","volume":"70","author":"C Tayman","year":"2011","unstructured":"Tayman C, Uckan D, Kilic E, et al. Mesenchymal stem cell therapy in necrotizing enterocolitis: a rat study. Pediatr Res. 2011;70:489\u201394.","journal-title":"Pediatr Res"},{"key":"1739_CR34","doi-asserted-by":"crossref","first-page":"300","DOI":"10.1136\/gutjnl-2012-303735","volume":"63","author":"A Zani","year":"2014","unstructured":"Zani A, Cananzi M, Fascetti-Leon F, et al. Amniotic fluid stem cells improve survival and enhance repair of damaged intestine in necrotising enterocolitis via a COX-2 dependent mechanism. Gut. 2014;63:300\u20139.","journal-title":"Gut"}],"container-title":["The Indian Journal of Pediatrics"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s12098-015-1739-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s12098-015-1739-x\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s12098-015-1739-x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,6,2]],"date-time":"2019-06-02T03:59:22Z","timestamp":1559447962000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s12098-015-1739-x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,3,26]]},"references-count":34,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2015,7]]}},"alternative-id":["1739"],"URL":"https:\/\/doi.org\/10.1007\/s12098-015-1739-x","relation":{},"ISSN":["0019-5456","0973-7693"],"issn-type":[{"value":"0019-5456","type":"print"},{"value":"0973-7693","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,3,26]]}}}