{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,9,4]],"date-time":"2023-09-04T06:12:05Z","timestamp":1693807925028},"reference-count":24,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2018,7,3]],"date-time":"2018-07-03T00:00:00Z","timestamp":1530576000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Indian J Pediatr"],"published-print":{"date-parts":[[2019,1]]},"DOI":"10.1007\/s12098-018-2734-9","type":"journal-article","created":{"date-parts":[[2018,7,3]],"date-time":"2018-07-03T02:31:10Z","timestamp":1530585070000},"page":"26-31","update-policy":"http:\/\/dx.doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Cytotoxic T- Lymphocyte Antigen-4 (CTLA4) Gene Expression and Urinary CTLA4 Levels in Idiopathic Nephrotic Syndrome"],"prefix":"10.1007","volume":"86","author":[{"given":"Om P","family":"Mishra","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Prashant","family":"Chhabra","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gopeshwar","family":"Narayan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pradeep","family":"Srivastava","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rajniti","family":"Prasad","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ankur","family":"Singh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Abhishek","family":"Abhinay","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vineeta V","family":"Batra","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2018,7,3]]},"reference":[{"key":"2734_CR1","doi-asserted-by":"publisher","first-page":"556","DOI":"10.1016\/S0140-6736(74)91880-7","volume":"2","author":"RJ Shalhoub","year":"1974","unstructured":"Shalhoub RJ. Pathogenesis of lipoid nephrosis: a disorder of T-cell function. Lancet. 1974;2:556\u201360.","journal-title":"Lancet"},{"key":"2734_CR2","doi-asserted-by":"publisher","first-page":"453","DOI":"10.1038\/ki.1991.232","volume":"40","author":"A Koyama","year":"1991","unstructured":"Koyama A, Fujisaki M, Kobayashi M, Igarashi M, Narita M. A glomerular permeability factor produced by human T cell hybridomas. Kidney Int. 1991;40:453\u201360.","journal-title":"Kidney Int"},{"key":"2734_CR3","first-page":"289","volume":"47","author":"V Daniel","year":"1997","unstructured":"Daniel V, Trautmann Y, Konrad M, Nayir A, Sch\u00e4rer K. T-lymphocyte populations, cytokines and other growth factors in serum and urine of children with idiopathic nephrotic syndrome. Clin Nephrol. 1997;47:289\u201397.","journal-title":"Clin Nephrol"},{"key":"2734_CR4","doi-asserted-by":"publisher","first-page":"334","DOI":"10.1159\/000046017","volume":"88","author":"K Matsumoto","year":"2001","unstructured":"Matsumoto K, Kanmatsuse K. Elevated interleukin-18 levels in the urine of nephrotic patients. Nephron. 2001;88:334\u20139.","journal-title":"Nephron"},{"key":"2734_CR5","doi-asserted-by":"publisher","first-page":"2115","DOI":"10.2215\/CJN.03800609","volume":"5","author":"ET McCarthy","year":"2010","unstructured":"McCarthy ET, Sharma M, Savin VJ. Circulating permeability factors in idiopathic nephrotic syndrome and focal segmental glomerulosclerosis. Clin J Am Soc Nephrol. 2010;5:2115\u201321.","journal-title":"Clin J Am Soc Nephrol"},{"key":"2734_CR6","doi-asserted-by":"publisher","first-page":"1390","DOI":"10.1172\/JCI20402","volume":"113","author":"J Reiser","year":"2004","unstructured":"Reiser J, von Gersdorff G, Loos M, et al. Induction of B7\u20131 in podocytes is associated with nephrotic syndrome. J Clin Invest. 2004;113:1390\u20137.","journal-title":"J Clin Invest"},{"key":"2734_CR7","doi-asserted-by":"publisher","first-page":"260","DOI":"10.1681\/ASN.2007080836","volume":"20","author":"EH Garin","year":"2009","unstructured":"Garin EH, Diaz LN, Mu W, et al. Urinary CD80 excretion increases in idiopathic minimal change disease. J Am Soc Nephrol. 2009;20:260\u20136.","journal-title":"J Am Soc Nephrol"},{"key":"2734_CR8","doi-asserted-by":"publisher","first-page":"296","DOI":"10.1038\/ki.2010.143","volume":"78","author":"EH Garin","year":"2010","unstructured":"Garin EH, Mu W, Arthur JM, et al. Urinary CD80 is elevated in minimal change disease but not in focal segmental glomerulosclerosis. Kidney Int. 2010;78:296\u2013302.","journal-title":"Kidney Int"},{"key":"2734_CR9","doi-asserted-by":"publisher","first-page":"1355","DOI":"10.1007\/s00467-017-3613-8","volume":"32","author":"OP Mishra","year":"2017","unstructured":"Mishra OP, Kumar R, Narayan G, et al. Toll-like receptor 3 (TLR-3), TLR-4 and CD80 expression in peripheral blood mononuclear cells and urinary CD80 levels in children with idiopathic nephrotic syndrome. Pediatr Nephrol. 2017;32:1355\u201361.","journal-title":"Pediatr Nephrol"},{"key":"2734_CR10","doi-asserted-by":"crossref","first-page":"3489","DOI":"10.4049\/jimmunol.151.7.3489","volume":"151","author":"T Lindsten","year":"1993","unstructured":"Lindsten T, Lee KP, Harris ES, et al. Characterisation of CTLA-4 structure and expression on human T cells. J Immunol. 1993;151:3489\u201399.","journal-title":"J Immunol"},{"key":"2734_CR11","doi-asserted-by":"publisher","first-page":"561","DOI":"10.1084\/jem.174.3.561","volume":"174","author":"PS Linsley","year":"1991","unstructured":"Linsley PS, Brady W, Urnes M, Grosmaire LS, Damle NK, Ledbetter JA. CTLA-4 is a second receptor for the B cell activation antigen B7. J Exp Med. 1991;174:561\u20139.","journal-title":"J Exp Med"},{"key":"2734_CR12","doi-asserted-by":"publisher","first-page":"783","DOI":"10.1084\/jem.184.2.783","volume":"184","author":"NJ Karandikar","year":"1996","unstructured":"Karandikar NJ, Vanderlugt CL, Walunas TL, Miller SD, Bluestone JA. CTLA-4: a negative regulator of autoimmune disease. J Exp Med. 1996;184:783\u20138.","journal-title":"J Exp Med"},{"key":"2734_CR13","doi-asserted-by":"publisher","first-page":"2333","DOI":"10.1007\/s00467-014-2874-8","volume":"29","author":"G Cara-Fuentes","year":"2014","unstructured":"Cara-Fuentes G, Wasserfall CH, Wang H, Johnson RJ, Garin EH. Minimal change disease: a dysregulation of the podocyte CD80-CTLA-4 axis? Pediatr Nephrol. 2014;29:2333\u201340.","journal-title":"Pediatr Nephrol"},{"key":"2734_CR14","doi-asserted-by":"publisher","first-page":"645","DOI":"10.1007\/s00467-010-1676-x","volume":"26","author":"M Shimada","year":"2011","unstructured":"Shimada M, Araya C, Rivard C, Ishimoto T, Johnson RJ, Garin EH. Minimal change disease: a \u2018 two-hit\u2019 podocyte immune disorder? Pediatr Nephrol. 2011;26:645\u20139.","journal-title":"Pediatr Nephrol"},{"key":"2734_CR15","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1007\/s00251-002-0429-9","volume":"54","author":"M M\u00e4urer","year":"2002","unstructured":"M\u00e4urer M, Loserth S, Kolb-M\u00e4urer A, et al. A polymorphism in the human cytotoxic T-lymphocyte antigen 4 (CTLA4) gene (exon 1 +49) alters T-cell activation. Immunogenetics. 2002;54:1\u20138.","journal-title":"Immunogenetics"},{"key":"2734_CR16","doi-asserted-by":"publisher","first-page":"121","DOI":"10.1186\/1471-2350-10-121","volume":"10","author":"EJ Carr","year":"2009","unstructured":"Carr EJ, Niederer HA, Williams J, et al. Confirmation of the genetic association of CTLA4 and PTPN22 with ANCA-associated vasculitis. BMC Med Genet. 2009;10:121.","journal-title":"BMC Med Genet"},{"key":"2734_CR17","doi-asserted-by":"publisher","first-page":"823","DOI":"10.1038\/sj.ejhg.5201423","volume":"13","author":"C Lei","year":"2005","unstructured":"Lei C, Dongqing Z, Yeqing S, et al. Association of the CTLA-4 gene with rheumatoid arthritis in the Chinese Han population. Eur J Hum Genet. 2005;13:823\u20138.","journal-title":"Eur J Hum Genet"},{"key":"2734_CR18","doi-asserted-by":"publisher","first-page":"2059","DOI":"10.1007\/s00467-012-2216-7","volume":"27","author":"JJ Wang","year":"2012","unstructured":"Wang JJ, Shi YP, Yue H, Chun W, Zou LP. CTLA-4 exon 1 +49A\/G polymorphism is associated with renal involvement in pediatric Henoch-Sch\u00f6nlein purpura. Pediatr Nephrol. 2012;27:2059\u201364.","journal-title":"Pediatr Nephrol"},{"key":"2734_CR19","doi-asserted-by":"publisher","first-page":"2800","DOI":"10.1093\/ndt\/gft381","volume":"28","author":"C Spink","year":"2013","unstructured":"Spink C, Stege G, Tenbrock K, Harendza S. The CTLA-4 +49GG genotype is associated with susceptibility for nephrotic kidney diseases. Nephrol Dial Transplant. 2013;28:2800\u20135.","journal-title":"Nephrol Dial Transplant"},{"key":"2734_CR20","doi-asserted-by":"publisher","first-page":"1074","DOI":"10.1053\/j.ajkd.2014.01.427","volume":"63","author":"K Ohl","year":"2014","unstructured":"Ohl K, Eberhardt C, Spink C, et al. CTLA4 polymorphisms in minimal change nephrotic syndrome in children: a case-control study. Am J Kidney Dis. 2014;63:1074\u20135.","journal-title":"Am J Kidney Dis"},{"key":"2734_CR21","doi-asserted-by":"publisher","first-page":"320","DOI":"10.1016\/j.semnephrol.2011.06.002","volume":"31","author":"T Ishimoto","year":"2011","unstructured":"Ishimoto T, Shimada M, Araya CE, Huskey J, Garin EH, Johnson RJ. Minimal change disease: a CD80 podocytopathy. Semin Nephrol. 2011;31:320\u20135.","journal-title":"Semin Nephrol"},{"key":"2734_CR22","first-page":"203","volume":"45","author":"Indian Pediatric Nephrology Group, Indian Academy of Pediatrics","year":"2008","unstructured":"Indian Pediatric Nephrology Group, Indian Academy of Pediatrics. Management of steroid sensitive nephrotic syndrome: revised guidelines. Indian Pediatr. 2008;45:203\u201314.","journal-title":"Indian Pediatr"},{"key":"2734_CR23","first-page":"35","volume":"46","author":"A Gulati","year":"2009","unstructured":"Gulati A, Bagga A, Gulati S, Mehta KP, Vijayakumar M; Indian Society of Pediatric Nephrology. Management of steroid resistant nephrotic syndrome. Indian Pediatr. 2009;46:35\u201347.","journal-title":"Indian Pediatr"},{"key":"2734_CR24","doi-asserted-by":"publisher","first-page":"145","DOI":"10.1038\/sj.gene.6363752","volume":"2","author":"A Ligers","year":"2001","unstructured":"Ligers A, Teleshova N, Masterman T, Huang WX, Hillert J. CTLA-4 gene expression is influenced by promoter and exon 1 polymorphisms. Genes Immun. 2001;2:145\u201352.","journal-title":"Genes Immun"}],"container-title":["The Indian Journal of Pediatrics"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s12098-018-2734-9\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s12098-018-2734-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s12098-018-2734-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,3]],"date-time":"2023-09-03T13:39:57Z","timestamp":1693748397000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s12098-018-2734-9"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,7,3]]},"references-count":24,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2019,1]]}},"alternative-id":["2734"],"URL":"https:\/\/doi.org\/10.1007\/s12098-018-2734-9","relation":{},"ISSN":["0019-5456","0973-7693"],"issn-type":[{"value":"0019-5456","type":"print"},{"value":"0973-7693","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,7,3]]},"assertion":[{"value":"17 March 2018","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"8 June 2018","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"3 July 2018","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with Ethical Standards"}},{"value":"None.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of Interest"}},{"value":"The study was supported by the Institutional Grants of Department of Pediatrics, Institute of Medical Sciences and School of Biochemical Engineering, Indian Institute of Technology, Banaras Hindu University, Varanasi, India.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Source of\u00a0Funding"}}]}}