{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,19]],"date-time":"2026-03-19T20:18:45Z","timestamp":1773951525814,"version":"3.50.1"},"reference-count":4,"publisher":"Springer Science and Business Media LLC","issue":"7","license":[{"start":{"date-parts":[[2023,6,1]],"date-time":"2023-06-01T00:00:00Z","timestamp":1685577600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2023,6,1]],"date-time":"2023-06-01T00:00:00Z","timestamp":1685577600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"funder":[{"DOI":"10.13039\/501100004595","name":"Universiti Sains Malaysia","doi-asserted-by":"publisher","award":["1001\/PPSG\/812158."],"award-info":[{"award-number":["1001\/PPSG\/812158."]}],"id":[{"id":"10.13039\/501100004595","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Indian J Pediatr"],"published-print":{"date-parts":[[2023,7]]},"DOI":"10.1007\/s12098-023-04601-0","type":"journal-article","created":{"date-parts":[[2023,6,1]],"date-time":"2023-06-01T06:02:22Z","timestamp":1685599342000},"page":"729-729","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Effects of Twin-Block Appliance Therapy on Urinary Leukotriene E4 and Serum C-Reactive Protein Levels in Obstructive Sleep Apnea Children with Class II Malocclusion and Mandibular Retrognathia: A Prospective Longitudinal Study"],"prefix":"10.1007","volume":"90","author":[{"given":"Maen","family":"Zreaqat","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3088-2169","authenticated-orcid":false,"given":"Rozita","family":"Hassan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rani","family":"Samsudin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sahal","family":"Alforaidi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2023,6,1]]},"reference":[{"key":"4601_CR1","doi-asserted-by":"publisher","first-page":"68","DOI":"10.1186\/s40510-014-0068-3","volume":"15","author":"S Ghodke","year":"2014","unstructured":"Ghodke S, Utreja AK, Singh SP, Jena AK. Effects of twin-block appliance on the anatomy of pharyngeal airway passage (PAP) in class II malocclusion subjects. Prog Orthod. 2014;15:68.","journal-title":"Prog Orthod"},{"key":"4601_CR2","doi-asserted-by":"publisher","first-page":"1053","DOI":"10.1007\/s11325-018-1636-4","volume":"22","author":"S Hoxha","year":"2018","unstructured":"Hoxha S, Kaya-Sezginer E, Bakar-Ates F, K\u00f6kt\u00fcrk O, Toygar-Memiko\u011flu U. Effect of semi-rapid maxillary expansion in children with obstructive sleep apnea syndrome: 5-month follow-up study. Sleep Breath. 2018;22:1053\u201361.","journal-title":"Sleep Breath"},{"key":"4601_CR3","doi-asserted-by":"publisher","first-page":"3383","DOI":"10.3390\/ijms19113383","volume":"19","author":"A Khalyfa","year":"2018","unstructured":"Khalyfa A, Kheirandish-Gozal L, Gozal D. Exosome and macrophage crosstalk in sleep-disordered breathing-induced metabolic dysfunction. Int J Mol Sci. 2018;19:3383.","journal-title":"Int J Mol Sci"},{"key":"4601_CR4","doi-asserted-by":"publisher","first-page":"330","DOI":"10.1164\/rccm.201106-1026OC","volume":"185","author":"J Kim","year":"2012","unstructured":"Kim J, Bhattacharjee R, Khalyfa A, et al. DNA methylation in inflammatory genes among children with obstructive sleep apnea. Am J Respir Crit Care Med. 2012;185:330\u20138.","journal-title":"Am J Respir Crit Care Med"}],"container-title":["Indian Journal of Pediatrics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12098-023-04601-0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s12098-023-04601-0\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12098-023-04601-0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,6,17]],"date-time":"2023-06-17T03:45:21Z","timestamp":1686973521000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s12098-023-04601-0"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,6,1]]},"references-count":4,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2023,7]]}},"alternative-id":["4601"],"URL":"https:\/\/doi.org\/10.1007\/s12098-023-04601-0","relation":{},"ISSN":["0019-5456","0973-7693"],"issn-type":[{"value":"0019-5456","type":"print"},{"value":"0973-7693","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,6,1]]},"assertion":[{"value":"13 October 2022","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"3 April 2023","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"1 June 2023","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"None.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of Interest"}},{"value":"This content has been made available to all.","name":"free","label":"Free to read"}]}}