{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,13]],"date-time":"2025-12-13T05:23:08Z","timestamp":1765603388388,"version":"3.48.0"},"reference-count":18,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2025,12,13]],"date-time":"2025-12-13T00:00:00Z","timestamp":1765584000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"},{"start":{"date-parts":[[2025,12,13]],"date-time":"2025-12-13T00:00:00Z","timestamp":1765584000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"name":"National Science Foundation, United States"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Biomol NMR Assign"],"published-print":{"date-parts":[[2026,12]]},"DOI":"10.1007\/s12104-025-10251-4","type":"journal-article","created":{"date-parts":[[2025,12,13]],"date-time":"2025-12-13T05:20:31Z","timestamp":1765603231000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Backbone NMR resonance assignments for the C2 domain of the Streptococcus mutans adhesin P1"],"prefix":"10.1007","volume":"20","author":[{"ORCID":"https:\/\/orcid.org\/0009-0001-7845-0699","authenticated-orcid":false,"given":"Emily-Qingqing","family":"Peng","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2548-6564","authenticated-orcid":false,"given":"M. Luiza Caldas","family":"Nogueira","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-3222-0010","authenticated-orcid":false,"given":"Chase","family":"Norton","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8952-086X","authenticated-orcid":false,"given":"L. Jeannine","family":"Brady","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5572-6859","authenticated-orcid":false,"given":"Joanna R.","family":"Long","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2025,12,13]]},"reference":[{"key":"10251_CR1","doi-asserted-by":"publisher","first-page":"5","DOI":"10.1128\/microbiolspec.GPP3-0042-2018","volume":"6","author":"J Abranches","year":"2018","unstructured":"Abranches J, Zeng L, Kajfasz JK et al (2018) Biology of oral Streptococci. Microbiol Spectr 6:5\u20136","journal-title":"Microbiol Spectr"},{"key":"10251_CR2","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1038\/s41598-020-62115-7","volume":"10","author":"AL Barran-Berdon","year":"2020","unstructured":"Barran-Berdon AL, Ocampo S, Haider M et al (2020) Enhanced purification coupled with biophysical analyses shows cross-\u03b2 structure as a core Building block for Streptococcus mutans functional amyloids. Sci Rep 10:1\u201311","journal-title":"Sci Rep"},{"key":"10251_CR3","doi-asserted-by":"publisher","first-page":"488","DOI":"10.1099\/mic.0.000443","volume":"163","author":"RN Besingi","year":"2017","unstructured":"Besingi RN, Wenderska IB, Senadheera DB et al (2017) Functional amyloids in Streptococcus mutans, their use as targets of biofilm inhibition and initial characterization of SMU_63c. Microbiology 163:488\u2013501. https:\/\/doi.org\/10.1099\/mic.0.000443","journal-title":"Microbiology"},{"key":"10251_CR4","doi-asserted-by":"publisher","first-page":"276","DOI":"10.1111\/j.1365-2958.2010.07212.x","volume":"77","author":"LJ Brady","year":"2010","unstructured":"Brady LJ, Maddocks SE, Larson MR (2010) The changing faces of Streptococcus antigen I\/II polypeptide family adhesins. Mol Microbiol 77:276\u2013286","journal-title":"Mol Microbiol"},{"key":"10251_CR5","doi-asserted-by":"publisher","first-page":"e01149","DOI":"10.1128\/AEM.01149-21","volume":"87","author":"NM di Cologna","year":"2021","unstructured":"di Cologna NM, Samaddar S, Valle CA et al (2021) Amyloid aggregation of Streptococcus mutans Cnm influences its collagen-binding activity. Appl Environ Microbiol 87:e01149\u2013e01121","journal-title":"Appl Environ Microbiol"},{"key":"10251_CR6","doi-asserted-by":"publisher","first-page":"W370","DOI":"10.1093\/nar\/gkv494","volume":"43","author":"NE Hafsa","year":"2015","unstructured":"Hafsa NE, Arndt D, Wishart DS (2015) CSI 3.0: a web server for identifying secondary and super-secondary structure in proteins using NMR chemical shifts. Nucleic Acids Res 43:W370\u2013W377","journal-title":"Nucleic Acids Res"},{"key":"10251_CR7","doi-asserted-by":"publisher","first-page":"15711","DOI":"10.1073\/pnas.1413018111","volume":"111","author":"KP Heim","year":"2014","unstructured":"Heim KP, Crowley PJ, Long JR et al (2014) An intramolecular lock facilitates folding and stabilizes the tertiary structure of Streptococcus mutans adhesin p1. Proc Natl Acad Sci U S A 111:15711\u201315716. https:\/\/doi.org\/10.1073\/pnas.1413018111","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10251_CR8","doi-asserted-by":"publisher","first-page":"9002","DOI":"10.1074\/jbc.M114.626663","volume":"290","author":"KP Heim","year":"2015","unstructured":"Heim KP, Sullan RMA, Crowley PJ et al (2015) Identification of a supramolecular functional architecture of Streptococcus mutans adhesin P1 on the bacterial cell. J Biol Chem 290:9002\u20139019. https:\/\/doi.org\/10.1074\/jbc.M114.626663","journal-title":"J Biol Chem"},{"key":"10251_CR9","doi-asserted-by":"publisher","first-page":"5983","DOI":"10.1073\/pnas.0912293107","volume":"107","author":"MR Larson","year":"2010","unstructured":"Larson MR, Rajashankar KR, Patel MH et al (2010) Elongated fibrillar structure of a streptococcal adhesin assembled by the high-affinity association of \u03b1-and PPII-helices. Proc Natl Acad Sci U S A 107:5983\u20135988","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10251_CR10","doi-asserted-by":"publisher","first-page":"21657","DOI":"10.1074\/jbc.M111.231100","volume":"286","author":"MR Larson","year":"2011","unstructured":"Larson MR, Rajashankar KR, Crowley PJ et al (2011) Crystal structure of the C-terminal region of Streptococcus mutans antigen I\/II and characterization of salivary agglutinin adherence domains. J Biol Chem 286:21657\u201321666. https:\/\/doi.org\/10.1074\/jbc.M111.231100","journal-title":"J Biol Chem"},{"key":"10251_CR11","doi-asserted-by":"publisher","unstructured":"Lemos JA, Palmer SR, Zeng L et al (2019) The biology of Streptococcus mutans. Microbiol Spectr 7(1). https:\/\/doi.org\/10.1128\/microbiolspecGPP3-0051-2018","DOI":"10.1128\/microbiolspec"},{"key":"10251_CR12","doi-asserted-by":"publisher","first-page":"2903","DOI":"10.1099\/mic.0.060855-0","volume":"158","author":"MW Oli","year":"2012","unstructured":"Oli MW, Otoo HN, Crowley PJ (2012) Functional amyloid formation by Streptococcus mutans. Microbiology 158:2903","journal-title":"Microbiology"},{"key":"10251_CR13","doi-asserted-by":"publisher","first-page":"293","DOI":"10.1007\/s12104-023-10158-y","volume":"17","author":"E-Q Peng","year":"2023","unstructured":"Peng E-Q, Caldas Nogueira ML, Rivi\u00e8re G (2023) Backbone NMR resonance assignments for the C terminal domain of the Streptococcus mutans adhesin P1. Biomol NMR Assign 17:293\u2013299","journal-title":"Biomol NMR Assign"},{"key":"10251_CR14","doi-asserted-by":"publisher","DOI":"10.1111\/febs.15158","author":"G Rivi\u00e8re","year":"2020","unstructured":"Rivi\u00e8re G, Peng EQ, Brotgandel A (2020) Characterization of an intermolecular quaternary interaction between discrete segments of the Streptococcus mutans adhesin P1 by NMR spectroscopy. FEBS J. https:\/\/doi.org\/10.1111\/febs.15158","journal-title":"FEBS J"},{"key":"10251_CR15","doi-asserted-by":"publisher","first-page":"486","DOI":"10.1128\/iai.28.2.486-493.1980","volume":"28","author":"MW Russell","year":"1980","unstructured":"Russell MW, Bergmeier LA, Zanders ED, Lehner T (1980) Protein antigens of Streptococcus mutans: purification and properties of a double antigen and its protease-resistant component. Infect Immun 28:486\u2013493","journal-title":"Infect Immun"},{"key":"10251_CR16","doi-asserted-by":"publisher","first-page":"153","DOI":"10.1007\/s10858-016-0017-1","volume":"64","author":"W Tang","year":"2016","unstructured":"Tang W, Bhatt A, Smith AN et al (2016) Specific binding of a naturally occurring amyloidogenic fragment of Streptococcus mutans adhesin P1 to intact P1 on the cell surface characterized by solid state NMR spectroscopy. J Biomol NMR 64:153\u2013164","journal-title":"J Biomol NMR"},{"key":"10251_CR17","doi-asserted-by":"publisher","first-page":"687","DOI":"10.1002\/prot.20449","volume":"59","author":"WF Vranken","year":"2005","unstructured":"Vranken WF, Boucher W, Stevens TJ (2005) The CCPN data model for NMR spectroscopy: development of a software pipeline. Proteins 59:687\u2013696","journal-title":"Proteins"},{"key":"10251_CR18","doi-asserted-by":"publisher","first-page":"e01661","DOI":"10.1128\/spectrum.01661-22","volume":"10","author":"E Yarmola","year":"2022","unstructured":"Yarmola E, Ishkov IP, di Cologna NM et al (2022) Amyloid aggregates are localized to the nonadherent detached fraction of aging Streptococcus mutans biofilms. Microbiol Spectr 10:e01661\u2013e01622","journal-title":"Microbiol Spectr"}],"container-title":["Biomolecular NMR Assignments"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12104-025-10251-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s12104-025-10251-4\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12104-025-10251-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,12,13]],"date-time":"2025-12-13T05:20:32Z","timestamp":1765603232000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s12104-025-10251-4"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,12,13]]},"references-count":18,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2026,12]]}},"alternative-id":["10251"],"URL":"https:\/\/doi.org\/10.1007\/s12104-025-10251-4","relation":{},"ISSN":["1874-2718","1874-270X"],"issn-type":[{"value":"1874-2718","type":"print"},{"value":"1874-270X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,12,13]]},"assertion":[{"value":"24 July 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"13 October 2025","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"13 December 2025","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare that they have no conflict of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}},{"value":"Not applicable.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"All the authors have seen and approved the submission of this manuscript.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}}],"article-number":"8"}}