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Moreover, rare botryoid (giant) fibroepithelial polyps may harbor this mutation. Herein, we describe the first reported case of a<jats:italic>DICER1-<\/jats:italic>mutated botryoid fibroepithelial polyp occurring within the parotid duct of a 65-year-old female who has no other features or family history of the DICER1 syndrome. Based on its distinctive morphology, we tested this lesion specifically for<jats:italic>DICER1<\/jats:italic>mutations and confirmed the presence of a pathogenic<jats:italic>DICER1<\/jats:italic>variant with a low allele frequency, consistent with a somatic mutation.<\/jats:p>","DOI":"10.1007\/s12105-021-01364-y","type":"journal-article","created":{"date-parts":[[2021,7,19]],"date-time":"2021-07-19T16:03:13Z","timestamp":1626710593000},"page":"573-580","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["DICER1-Mutated Botryoid Fibroepithelial Polyp of the Parotid Duct: Report of the First Case"],"prefix":"10.1007","volume":"16","author":[{"given":"Ramona","family":"Erber","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Raimund","family":"Preidl","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert","family":"Stoehr","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Florian","family":"Haller","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arndt","family":"Hartmann","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marco","family":"Kesting","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0445-8161","authenticated-orcid":false,"given":"Abbas","family":"Agaimy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2021,7,19]]},"reference":[{"issue":"3","key":"1364_CR1","doi-asserted-by":"publisher","first-page":"223","DOI":"10.1016\/j.ceb.2004.04.003","volume":"16","author":"EP Murchison","year":"2004","unstructured":"Murchison EP, Hannon GJ. miRNAs on the move: miRNA biogenesis and the RNAi machinery. 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