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The NGS part of the study was carried out at the University Hospitals Cleveland Medical Center, Cleveland OH. The NGS part of the study was approved by the University of Minnesota Institutional Review Board (ID: 00012651). The University of Minnesota reviewed the study and determined that the proposed activity is not research involving human subjects as defined by DHHS and FDA regulations. To arrive to this determination, the University of Minnesota IRB used \u201cWORKSHEET: Human Research (HRP-310).\u201d Based on that, ongoing IRB review and approval for this activity is not required.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical Approval"}},{"value":"The histopathologic, immunohistochemical, and NGS parts of the study were exempt from the institutional review board (University of Minnesota IRB: ID: 00012651).","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to Participate"}},{"value":"The patient\u2019s information, excluding age and gender, cannot be identified. Please note that the patient was lost to follow-up. Repeated attempts to communicate with the patient were unsuccessful. The NGS part was performed for diagnostic\/investigative purposes.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for Publication"}}]}}