{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,2]],"date-time":"2026-06-02T12:11:14Z","timestamp":1780402274136,"version":"3.54.1"},"reference-count":25,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2025,3,15]],"date-time":"2025-03-15T00:00:00Z","timestamp":1741996800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2025,3,15]],"date-time":"2025-03-15T00:00:00Z","timestamp":1741996800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"funder":[{"name":"National Council for Scientific and Technological Development (CNPq)\/PIBIC Program"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Head and Neck Pathol"],"DOI":"10.1007\/s12105-025-01771-5","type":"journal-article","created":{"date-parts":[[2025,3,15]],"date-time":"2025-03-15T01:15:15Z","timestamp":1742001315000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Intraneural Pseudoperineuriomatous Proliferations and Traumatic Neuromas: A Retrospective Multicenter Study of Clinicopathological Characteristics"],"prefix":"10.1007","volume":"19","author":[{"given":"Jully Elisabeth","family":"Gundlach","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Victor Angelo Martins","family":"Montalli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Larissa Araujo","family":"Agatti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thamiris Castro","family":"Abrantes","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kelly Tambasco","family":"Bezerra","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aline Corr\u00eaa","family":"Abrah\u00e3o","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M\u00e1rio Jos\u00e9","family":"Roma\u00f1ach","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Silvio Luiz Vieira","family":"Oliveira","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nara Ligia Martins","family":"Almeida","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vanessa Soares","family":"Lara","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fernanda Arag\u00e3o","family":"Felix","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patr\u00edcia Carlos","family":"Caldeira","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lucas Guimar\u00e3es","family":"Abreu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ricardo Alves","family":"Mesquita","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cristiane","family":"Furuse","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3930-4274","authenticated-orcid":false,"given":"Ana Lia","family":"Anbinder","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2025,3,15]]},"reference":[{"issue":"4","key":"1771_CR1","doi-asserted-by":"publisher","first-page":"625","DOI":"10.5858\/2007-131-625-PADAUP","volume":"131","author":"RS Macarenco","year":"2007","unstructured":"Macarenco RS, Ellinger F, Oliveira AM (2007) Perineurioma: a distinctive and underrecognized peripheral nerve sheath neoplasm. Arch Pathol Lab Med 131(4):625\u2013636","journal-title":"Arch Pathol Lab Med"},{"issue":"9","key":"1771_CR2","doi-asserted-by":"publisher","first-page":"678","DOI":"10.1097\/00000478-198809000-00004","volume":"12","author":"A Ariza","year":"1988","unstructured":"Ariza A, Bilbao JM, Rosai J (1988) Immunohistochemical detection of epithelial membrane antigen in normal perineurial cells and perineurioma. Am J Surg Pathol 12(9):678\u2013683","journal-title":"Am J Surg Pathol"},{"issue":"3","key":"1771_CR3","first-page":"109","volume":"11","author":"SM Chou","year":"1992","unstructured":"Chou SM (1992) Immunohistochemical and ultrastructural classification of peripheral neuropathies with onion-bulbs. Clin Neuropathol 11(3):109\u2013114","journal-title":"Clin Neuropathol"},{"issue":"11","key":"1771_CR4","doi-asserted-by":"publisher","first-page":"3539","DOI":"10.1007\/s00701-023-05765-6","volume":"165","author":"KA Lenartowicz","year":"2023","unstructured":"Lenartowicz KA, Smith BW, Jack MM, Wilson TJ, Klein CJ, Amrami KK et al (2023) What is new in intraneural perineurioma? Acta Neurochir (Wien) 165(11):3539\u20133547","journal-title":"Acta Neurochir (Wien)"},{"issue":"4","key":"1771_CR5","doi-asserted-by":"publisher","first-page":"428","DOI":"10.1016\/j.oooo.2020.07.004","volume":"130","author":"E Ko","year":"2020","unstructured":"Ko E, McNamara K, Ditty D, Alawi F (2020) Intraneural perineurioma of the mandible: case series of a rare entity. Oral Surg Oral Med Oral Pathol Oral Radiol 130(4):428\u2013432","journal-title":"Oral Surg Oral Med Oral Pathol Oral Radiol"},{"issue":"1","key":"1771_CR6","doi-asserted-by":"publisher","first-page":"71","DOI":"10.1080\/01913123.2020.1858212","volume":"45","author":"HR Dom\u00ednguez-Malag\u00f3n","year":"2021","unstructured":"Dom\u00ednguez-Malag\u00f3n HR, Serrano-Ar\u00e9valo ML, Maldonado J, Ch\u00e1vez J, Toussaint-Caire S, de Almeida OPD, Lino-Silva LS (2021) Perineurioma versus meningioma. A multi-institutional immunohistochemical and ultrastructural study. Ultrastruct Pathol 45(1):71\u201377","journal-title":"Ultrastruct Pathol"},{"issue":"4","key":"1771_CR7","doi-asserted-by":"publisher","first-page":"1379","DOI":"10.1111\/odi.14389","volume":"29","author":"AA Leite","year":"2023","unstructured":"Leite AA, Pires TL, Silva LC, Penafort PVM, Vargas PA (2023) Lobulated nodule arising on the tongue in a young patient. Oral Dis 29(4):1379\u20131381","journal-title":"Oral Dis"},{"issue":"4","key":"1771_CR8","doi-asserted-by":"publisher","first-page":"334","DOI":"10.1007\/s12105-013-0446-z","volume":"7","author":"IG Koutlas","year":"2013","unstructured":"Koutlas IG, Scheithauer BW (2013) On pseudo-onion bulb intraneural proliferations of the non-major nerves of the oral mucosa. Head Neck Pathol 7(4):334\u2013343","journal-title":"Head Neck Pathol"},{"key":"1771_CR9","doi-asserted-by":"publisher","DOI":"10.55418\/9781933477305","volume-title":"Atlas of tumor pathology, Series 4: tumors of the peripheral nervous system","author":"C Antonescu","year":"2013","unstructured":"Antonescu C, Scheithauer B, Woodruff J (2013) Atlas of tumor pathology, Series 4: tumors of the peripheral nervous system. ARP Press, New York"},{"key":"1771_CR10","doi-asserted-by":"publisher","DOI":"10.2174\/0118742106284558240424080759","author":"ACR Carnevalli","year":"2024","unstructured":"Carnevalli ACR, Dias da Silva SMS, da SilvaLeite LS, de Moura VT, Kitakawa D, da Silva Peralta F et al (2024) A clinical appearance of traumatic fibroma with a distinct and rare histological diagnosis\u2013insights of pseudo perineurioma\u2014Case Report. Open Dent J. https:\/\/doi.org\/10.2174\/0118742106284558240424080759","journal-title":"Open Dent J."},{"issue":"4","key":"1771_CR11","doi-asserted-by":"publisher","first-page":"475","DOI":"10.1007\/s12105-016-0725-6","volume":"10","author":"RJ Vargo","year":"2016","unstructured":"Vargo RJ, Potluri A, Bauer RE, Seethala RR, Bilodeau EA (2016) Intraoral pseudo-onion bulb intraneural proliferations in a patient with hemimandibular hyperplasia: a case report and review of the literature. Head Neck Pathol 10(4):475\u2013480","journal-title":"Head Neck Pathol"},{"key":"1771_CR12","doi-asserted-by":"publisher","first-page":"100009","DOI":"10.1016\/j.xhgg.2020.100009","volume":"1","author":"IG Koutlas","year":"2020","unstructured":"Koutlas IG, Anbinder A-L, Alshagroud R, Rodrigues Cavalcante AS, Al Kindi M, Crenshaw MM et al (2020) Orofacial overgrowth with peripheral nerve enlargement and perineuriomatous pseudo-onion bulb proliferations is part of the PIK3CA-related overgrowth spectrum. Hum Genet Genom Adv 1:100009","journal-title":"Hum Genet Genom Adv"},{"issue":"1","key":"1771_CR13","doi-asserted-by":"publisher","first-page":"43","DOI":"10.1590\/S1806-83242009000100008","volume":"23","author":"JT Salla","year":"2009","unstructured":"Salla JT, Johann ACBR, Garcia BG, Aguiar MCF, Mesquita RA (2009) Retrospective analysis of oral peripheral nerve sheath tumors in Brazilians. Braz Oral Res 23(1):43\u201348","journal-title":"Braz Oral Res"},{"key":"1771_CR14","doi-asserted-by":"publisher","first-page":"e1612020","DOI":"10.5935\/1676-2444.20200002","volume":"56","author":"LCN Marinho","year":"2020","unstructured":"Marinho LCN, Santos HBP, Morais EF, Freitas RA (2020) Benign neural lesions of the oral and maxillofacial complex: a 48-year-retrospective study. J Bras Patol Med Lab 56:e1612020","journal-title":"J Bras Patol Med Lab"},{"issue":"4","key":"1771_CR15","doi-asserted-by":"publisher","first-page":"395","DOI":"10.1016\/j.tripleo.2004.08.011","volume":"99","author":"AR Vora","year":"2005","unstructured":"Vora AR, Loescher AR, Craig GT, Boissonade FM, Robinson PP (2005) A light microscopical study on the structure of traumatic neuromas of the human lingual nerve. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 99(4):395\u2013403","journal-title":"Oral Surg Oral Med Oral Pathol Oral Radiol Endod"},{"issue":"4","key":"1771_CR16","doi-asserted-by":"publisher","first-page":"394","DOI":"10.1016\/0030-4220(81)90149-3","volume":"51","author":"TC Sist","year":"1981","unstructured":"Sist TC, Greene GW (1981) Traumatic neuroma of the oral cavity. Report of thirty-one new cases and review of the literature. Oral Surg Oral Med Oral Pathol 51(4):394\u2013402","journal-title":"Oral Surg Oral Med Oral Pathol"},{"issue":"8","key":"1771_CR17","doi-asserted-by":"publisher","first-page":"e721","DOI":"10.4317\/jced.55944","volume":"11","author":"P Tamiolakis","year":"2019","unstructured":"Tamiolakis P, Chrysomali E, Sklavounou-Andrikopoulou A, Nikitakis NG (2019) Oral neural tumors: clinicopathologic analysis of 157 cases and review of the literature. J Clin Exp Dent 11(8):e721\u2013e731","journal-title":"J Clin Exp Dent"},{"issue":"9","key":"1771_CR18","doi-asserted-by":"publisher","first-page":"963","DOI":"10.1016\/0278-2391(90)90010-Y","volume":"48","author":"MJ Peszkowski","year":"1990","unstructured":"Peszkowski MJ, Larsson A (1990) Extraosseous and intraosseous oral traumatic neuromas and their association with tooth extraction. J Oral Maxillofac Surg 48(9):963\u2013967","journal-title":"J Oral Maxillofac Surg"},{"issue":"7","key":"1771_CR19","doi-asserted-by":"publisher","first-page":"392","DOI":"10.1111\/j.1600-0714.2006.00451.x","volume":"35","author":"AV Jones","year":"2006","unstructured":"Jones AV, Franklin CD (2006) An analysis of oral and maxillofacial pathology found in adults over a 30-year period. J Oral Pathol Med 35(7):392\u2013401","journal-title":"J Oral Pathol Med"},{"issue":"5","key":"1771_CR20","doi-asserted-by":"publisher","first-page":"605","DOI":"10.1016\/S1079-2104(99)70142-3","volume":"87","author":"RK McDaniel","year":"1999","unstructured":"McDaniel RK (1999) Subepithelial nerve plexus (with ganglion cells) associated with taste buds. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 87(5):605\u2013609","journal-title":"Oral Surg Oral Med Oral Pathol Oral Radiol Endod"},{"issue":"4","key":"1771_CR21","doi-asserted-by":"publisher","first-page":"348","DOI":"10.1111\/j.1600-0714.2011.01101.x","volume":"41","author":"I Allon","year":"2012","unstructured":"Allon I, Allon DM, Hirshberg A, Shlomi B, Lifschitz-Mercer B, Kaplan I (2012) Oral neurovascular hamartoma: a lesion searching for a name. J Oral Pathol Med 41(4):348\u2013353","journal-title":"J Oral Pathol Med"},{"issue":"4","key":"1771_CR22","doi-asserted-by":"publisher","first-page":"572","DOI":"10.1016\/j.mehy.2008.05.010","volume":"71","author":"R Folt\u00e1n","year":"2008","unstructured":"Folt\u00e1n R, Kl\u00edma K, \u0160pa\u010dkov\u00e1 J, \u0160ed\u00fd J (2008) Mechanism of traumatic neuroma development. Med Hypotheses 71(4):572\u2013576","journal-title":"Med Hypotheses"},{"issue":"1","key":"1771_CR23","doi-asserted-by":"publisher","first-page":"74","DOI":"10.1016\/j.archoralbio.2006.08.015","volume":"52","author":"AR Vora","year":"2007","unstructured":"Vora AR, Bodell SM, Loescher AR, Smith KG, Robinson PP, Boissonade FM (2007) Inflammatory cell accumulation in traumatic neuromas of the human lingual nerve. Arch Oral Biol 52(1):74\u201382","journal-title":"Arch Oral Biol"},{"issue":"4","key":"1771_CR24","doi-asserted-by":"publisher","first-page":"713","DOI":"10.1016\/S0896-6273(01)80030-1","volume":"23","author":"E Parmantier","year":"1999","unstructured":"Parmantier E, Lynn B, Lawson D, Turmaine M, Namini SS, Chakrabarti L et al (1999) Schwann cell-derived Desert hedgehog controls the development of peripheral nerve sheaths. Neuron 23(4):713\u2013724","journal-title":"Neuron"},{"issue":"1","key":"1771_CR25","doi-asserted-by":"publisher","first-page":"196","DOI":"10.1111\/j.1749-6632.1999.tb08582.x","volume":"883","author":"R Mirsky","year":"1999","unstructured":"Mirsky R, Parmantier E, McMahon AP, Jessen KR (1999) Schwann cell-derived desert hedgehog signals nerve sheath formation. Ann N Y Acad Sci 883(1):196\u2013202","journal-title":"Ann N Y Acad Sci"}],"container-title":["Head and Neck Pathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12105-025-01771-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s12105-025-01771-5","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12105-025-01771-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,1,5]],"date-time":"2026-01-05T04:53:36Z","timestamp":1767588816000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s12105-025-01771-5"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,3,15]]},"references-count":25,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2025,12]]}},"alternative-id":["1771"],"URL":"https:\/\/doi.org\/10.1007\/s12105-025-01771-5","relation":{},"ISSN":["1936-0568"],"issn-type":[{"value":"1936-0568","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,3,15]]},"assertion":[{"value":"27 January 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"27 February 2025","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"15 March 2025","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare that they have no conflict of interest. This study was presented at the 48th Brazilian Congress of Stomatology and Oral Pathology (2023).","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"This study was approved by the Institutional Ethics Committee (CAAE: 48569921.4.0000.0077).","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical Approval"}},{"value":"For this type of study formal consent is not required.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to Participate"}},{"value":"For this type of study consent for publication is not required.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to Publish"}}],"article-number":"32"}}