{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,10]],"date-time":"2026-11-10T21:08:07Z","timestamp":1794344887080,"version":"4.9.0"},"reference-count":16,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2025,11,10]],"date-time":"2025-11-10T00:00:00Z","timestamp":1762732800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2025,11,10]],"date-time":"2025-11-10T00:00:00Z","timestamp":1762732800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Head and Neck Pathol"],"DOI":"10.1007\/s12105-025-01859-y","type":"journal-article","created":{"date-parts":[[2025,11,10]],"date-time":"2025-11-10T11:36:20Z","timestamp":1762774580000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Subglottic Laryngeal Salivary Gland Intraductal Papillary Mucinous Neoplasm with GNAS Mutation: A Case Report and Review of the Literature"],"prefix":"10.1007","volume":"19","author":[{"ORCID":"https:\/\/orcid.org\/0009-0005-1668-961X","authenticated-orcid":false,"given":"Benjamin","family":"Champion","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Benjamin","family":"Ryan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chady","family":"Sader","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Connull","family":"Leslie","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chris","family":"Van Vliet","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2025,11,10]]},"reference":[{"issue":"2","key":"1859_CR1","doi-asserted-by":"publisher","first-page":"183","DOI":"10.1111\/his.15289","volume":"86","author":"RA Wolk","year":"2025","unstructured":"Wolk RA, Cipriani NA (2025) Update of newly-recognized salivary gland neoplasms: molecular and immunohistochemical findings and clinical importance. Histopathology 86(2):183\u2013198. https:\/\/doi.org\/10.1111\/his.15289","journal-title":"Histopathology"},{"key":"1859_CR2","unstructured":"Skalova A, Thompson LDR, Bishop JA, et al. (2023) Salivary gland tumours: Introduction. In: WHO Classification of Tumours Editorial Board. Head and neck tumours [Internet]. Lyon (France): International Agency for Research on Cancer. (WHO classification of tumours series, 5th ed.; vol. 9). Available from: https:\/\/tumourclassification.iarc.who.int\/chapters\/52"},{"key":"1859_CR3","unstructured":"Rooper LM, Agaimy A, Bishop JA, et al. (2023) Mucinous adenocarcinoma. In: WHO Classification of Tumours Editorial Board. Head and neck tumours [Internet]. Lyon (France): International Agency for Research on Cancer. (WHO classification of tumours series, 5th ed.; vol. 9). Available from: https:\/\/tumourclassification.iarc.who.int\/chapters\/52"},{"issue":"1","key":"1859_CR4","doi-asserted-by":"publisher","first-page":"70","DOI":"10.1111\/jop.13588","volume":"54","author":"AB Soares","year":"2025","unstructured":"Soares AB, Teixeira LN, Melo JVBC et al (2025) Intraductal papillary mucinous neoplasm: new insights into its origin and nomenclatures. J Oral Pathol Med 54(1):70\u201375. https:\/\/doi.org\/10.1111\/jop.13588","journal-title":"J Oral Pathol Med"},{"issue":"2","key":"1859_CR5","doi-asserted-by":"publisher","first-page":"467","DOI":"10.1007\/s12105-023-01524-2","volume":"17","author":"S Patel","year":"2023","unstructured":"Patel S, Wald AI, Bastaki JM et al (2023) NKX3.1 expression and molecular characterization of secretory myoepithelial carcinoma (SMCA): advancing the case for a salivary mucous acinar phenotype. Head Neck Pathol 17(2):467\u2013478. https:\/\/doi.org\/10.1007\/s12105-023-01524-2","journal-title":"Head Neck Pathol"},{"key":"1859_CR6","unstructured":"Yoshida A, Beasley MB (2021) Mucous gland adenoma of the lung. In: WHO Classification of Tumours Editorial Board. Thoracic tumours [Internet]. Lyon (France): International Agency for Research on Cancer. (WHO classification of tumours series, 5th ed.; vol. 5). Available from: https:\/\/tumourclassification.iarc.who.int\/chapters\/35"},{"issue":"6","key":"1859_CR7","doi-asserted-by":"publisher","DOI":"10.1016\/j.modpat.2023.100182","volume":"36","author":"E Sasaki","year":"2023","unstructured":"Sasaki E, Masago K, Kogure Y et al (2023) Mucous gland adenoma of the lung: a neoplastic counterpart of mucinous bronchial glands. Mod Pathol 36(6):100182. https:\/\/doi.org\/10.1016\/j.modpat.2023.100182","journal-title":"Mod Pathol"},{"issue":"6","key":"1859_CR8","doi-asserted-by":"publisher","first-page":"E203","DOI":"10.1002\/dc.24674","volume":"49","author":"R Kojima","year":"2021","unstructured":"Kojima R, Morimoto J, Ishida Y et al (2021) A bronchial mucous gland adenoma harboring GNAS R201C mutation. Diagn Cytopathol 49(6):E203\u2013E206. https:\/\/doi.org\/10.1002\/dc.24674","journal-title":"Diagn Cytopathol"},{"issue":"5","key":"1859_CR9","doi-asserted-by":"publisher","first-page":"796","DOI":"10.1016\/j.prp.2018.03.006","volume":"214","author":"A Miura","year":"2018","unstructured":"Miura A, Mori T, Yoshida A et al (2018) Primary adenocarcinoma of the trachea revealing a mucinous bronchial gland cell origin. Pathol Res Pract 214(5):796\u2013799. https:\/\/doi.org\/10.1016\/j.prp.2018.03.006","journal-title":"Pathol Res Pract"},{"issue":"6","key":"1859_CR10","doi-asserted-by":"publisher","first-page":"1327","DOI":"10.1007\/s00428-024-03956-9","volume":"486","author":"C Chen","year":"2025","unstructured":"Chen C, Wu H, Yin W et al (2025) Bronchial salivary gland-type mucinous adenocarcinoma harboring a GNAS mutation: a novel lung cancer entity? A case report. Virchows Arch 486(6):1327\u20131331. https:\/\/doi.org\/10.1007\/s00428-024-03956-9","journal-title":"Virchows Arch"},{"issue":"12","key":"1859_CR11","doi-asserted-by":"publisher","first-page":"1720","DOI":"10.1038\/modpathol.2017.88","volume":"30","author":"LL Ritterhouse","year":"2017","unstructured":"Ritterhouse LL, Vivero M, Mino-Kenudson M et al (2017) GNAS mutations in primary mucinous and non-mucinous lung adenocarcinomas. Mod Pathol 30(12):1720\u20131727. https:\/\/doi.org\/10.1038\/modpathol.2017.88","journal-title":"Mod Pathol"},{"key":"1859_CR12","unstructured":"Catalogue Of Somatic Mutations In Cancer (COSMIC) Mutation COSV55670349, GRCh38. COSMIC v102. https:\/\/cancer.sanger.ac.uk\/cosmic\/mutation\/overview?id=120695396. Accessed 08 October 2025."},{"issue":"8","key":"1859_CR13","doi-asserted-by":"publisher","first-page":"1076","DOI":"10.1097\/PAS.0000000000001080","volume":"42","author":"A Agaimy","year":"2018","unstructured":"Agaimy A, Mueller SK, Bumm K et al (2018) Intraductal papillary mucinous neoplasms of minor salivary glands with AKT1 p.Glu17Lys mutation. Am J Surg Pathol 42(8):1076\u20131082. https:\/\/doi.org\/10.1097\/PAS.0000000000001080","journal-title":"Am J Surg Pathol"},{"issue":"3","key":"1859_CR14","doi-asserted-by":"publisher","first-page":"411","DOI":"10.1111\/his.13990","volume":"76","author":"M Nakaguro","year":"2020","unstructured":"Nakaguro M, Urano M, Ogawa I et al (2020) Histopathological evaluation of minor salivary gland papillary-cystic tumours: focus on genetic alterations in sialadenoma papilliferum and intraductal papillary mucinous neoplasm. Histopathology 76(3):411\u2013422. https:\/\/doi.org\/10.1111\/his.13990","journal-title":"Histopathology"},{"issue":"4","key":"1859_CR15","doi-asserted-by":"publisher","first-page":"1114","DOI":"10.1007\/s12105-022-01471-4","volume":"16","author":"M Nakaguro","year":"2022","unstructured":"Nakaguro M, Sadow PM, Hu R et al (2022) NKX3.1 expression in salivary gland \u201cintraductal\u201d papillary mucinous neoplasm: a low-grade subtype of salivary gland mucinous adenocarcinoma. Head Neck Pathol 16(4):1114\u20131123. https:\/\/doi.org\/10.1007\/s12105-022-01471-4","journal-title":"Head Neck Pathol"},{"issue":"10","key":"1859_CR16","doi-asserted-by":"publisher","first-page":"1337","DOI":"10.1097\/PAS.0000000000001688","volume":"45","author":"LM Rooper","year":"2021","unstructured":"Rooper LM, Argyris PP, Thompson LDR et al (2021) Salivary mucinous adenocarcinoma is a histologically diverse single entity with recurrent AKT1 E17K mutations: clinicopathologic and molecular characterization with proposal for a unified classification. Am J Surg Pathol 45(10):1337\u20131347. https:\/\/doi.org\/10.1097\/PAS.0000000000001688","journal-title":"Am J Surg Pathol"}],"container-title":["Head and Neck Pathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12105-025-01859-y.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s12105-025-01859-y","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12105-025-01859-y.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,1,5]],"date-time":"2026-01-05T04:53:16Z","timestamp":1767588796000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s12105-025-01859-y"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,11,10]]},"references-count":16,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2025,12]]}},"alternative-id":["1859"],"URL":"https:\/\/doi.org\/10.1007\/s12105-025-01859-y","relation":{},"ISSN":["1936-0568"],"issn-type":[{"value":"1936-0568","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,11,10]]},"assertion":[{"value":"3 September 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"16 October 2025","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"10 November 2025","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare no competing interests.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and\/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}},{"value":"Informed consent was obtained from all individual participants included in the study.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to participate"}},{"value":"Consent for publication was obtained for every individual person\u2019s data included in the study.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}}],"article-number":"128"}}