{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,11]],"date-time":"2026-01-11T22:34:16Z","timestamp":1768170856118,"version":"3.49.0"},"reference-count":28,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2026,1,8]],"date-time":"2026-01-08T00:00:00Z","timestamp":1767830400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2026,1,8]],"date-time":"2026-01-08T00:00:00Z","timestamp":1767830400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Head and Neck Pathol"],"DOI":"10.1007\/s12105-025-01879-8","type":"journal-article","created":{"date-parts":[[2026,1,8]],"date-time":"2026-01-08T12:51:54Z","timestamp":1767876714000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["A Case Report of Primitive Myxoid Mesenchymal Tumor of Infancy (PMMTI) with BCOR-ITD Genetic Alteration in the Sinonasal Cavity and Review of Literature"],"prefix":"10.1007","volume":"20","author":[{"given":"WanNi","family":"Xu","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yu","family":"Gu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhe","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"LiYing","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2026,1,8]]},"reference":[{"issue":"9","key":"1879_CR1","doi-asserted-by":"publisher","DOI":"10.7759\/cureus.29128PMID:36259025;PMCID:PMC9559984","volume":"14","author":"S Kumari","year":"2022","unstructured":"Kumari S, Pandey S, Verma M, Rana AK, Kumari S et al (2022) Clinicopathological challenges in tumors of the nasal cavity and paranasal sinuses: our experience. Cureus 14(9):e29128. https:\/\/doi.org\/10.7759\/cureus.29128PMID:36259025;PMCID:PMC9559984","journal-title":"Cureus"},{"issue":"3","key":"1879_CR2","doi-asserted-by":"publisher","first-page":"388","DOI":"10.1097\/01.pas.0000190784.18198.d8","volume":"30","author":"R Alaggio","year":"2006","unstructured":"Alaggio R, Ninfo V, Rosolen A, Coffin CM (2006) Primitive myxoid mesenchymal tumor of infancy: a clinicopathologic report of 6 cases. Am J Surg Pathol 30(3):388\u2013394. https:\/\/doi.org\/10.1097\/01.pas.0000190784.18198.d8","journal-title":"Am J Surg Pathol"},{"issue":"8","key":"1879_CR3","doi-asserted-by":"publisher","first-page":"1009","DOI":"10.1097\/PAS.0000000000000629","volume":"40","author":"YC Kao","year":"2016","unstructured":"Kao YC, Sung YS, Zhang L, Huang SC, Argani P, Chung CT et al (2016) Recurrent BCOR internal tandem duplication and YWHAE-NUTM2B fusions in soft tissue undifferentiated round cell sarcoma of infancy: overlapping genetic features with clear cell sarcoma of kidney. Am J Surg Pathol 40(8):1009\u20131020. https:\/\/doi.org\/10.1097\/PAS.0000000000000629","journal-title":"Am J Surg Pathol"},{"key":"1879_CR4","volume-title":"WHO classification of tumours: Paediatric tumours","author":"WHO Classification of Pediatric Tumors","year":"2023","unstructured":"WHO Classification of Pediatric Tumors (2023) WHO classification of tumours: Paediatric tumours, 5th edn. International Agency for Research on Cancer, Lyon","edition":"5"},{"issue":"1","key":"1879_CR5","doi-asserted-by":"publisher","first-page":"75","DOI":"10.2350\/09-12-0770-CR.1","volume":"14","author":"L Mulligan","year":"2011","unstructured":"Mulligan L, O\u2019Meara A, Orr D, Eadie P, Hayes R, McDermott M (2011) Primitive myxoid mesenchymal tumor of infancy: a report of a further case with locally aggressive behavior. Pediatr Dev Pathol 14(1):75\u201379. https:\/\/doi.org\/10.2350\/09-12-0770-CR.1","journal-title":"Pediatr Dev Pathol"},{"issue":"1","key":"1879_CR6","doi-asserted-by":"publisher","first-page":"e135","DOI":"10.1097\/MPH.0000000000002474","volume":"45","author":"M Haga","year":"2023","unstructured":"Haga M, Motojima Y, Masuda W, Fujino T, Tamaru JI, Nakamura T et al (2023) Primitive myxoid mesenchymal tumor of infancy with fatal hemorrhage in utero: a case report and literature review. J Pediatr Hematol Oncol 45(1):e135\u2013e138. https:\/\/doi.org\/10.1097\/MPH.0000000000002474","journal-title":"J Pediatr Hematol Oncol"},{"issue":"6","key":"1879_CR7","doi-asserted-by":"publisher","first-page":"635","DOI":"10.1111\/j.1525-1470.2010.01323.x","volume":"27","author":"J Lam","year":"2010","unstructured":"Lam J, Lara-Corrales I, Cammisuli S, Somers GR, Pope E (2010) Primitive myxoid mesenchymal tumor of infancy in a preterm infant. Pediatr Dermatol 27(6):635\u2013637. https:\/\/doi.org\/10.1111\/j.1525-1470.2010.01323.x","journal-title":"Pediatr Dermatol"},{"issue":"8","key":"1879_CR8","doi-asserted-by":"publisher","first-page":"549","DOI":"10.1111\/j.1440-1827.2012.02836.x","volume":"62","author":"Q Gong","year":"2012","unstructured":"Gong Q, Wang Z, Li X, Fan Q (2012) Primitive myxoid mesenchymal tumor of infancy: report of two cases and review of the literature. Pathol Int 62(8):549\u2013553. https:\/\/doi.org\/10.1111\/j.1440-1827.2012.02836.x","journal-title":"Pathol Int"},{"issue":"2","key":"1879_CR9","doi-asserted-by":"publisher","first-page":"109","DOI":"10.1007\/s00795-013-0032-1","volume":"46","author":"TC Su","year":"2013","unstructured":"Su TC, Hwang MJ, Li CF, Wang SC, Lee CH, Chen CJ (2013) A rare malignant tumor of scalp in a 3-month-old Taiwanese infancy: case report of primitive myxoid mesenchymal tumor of infancy with molecular study. Med Mol Morphol 46(2):109\u2013113. https:\/\/doi.org\/10.1007\/s00795-013-0032-1","journal-title":"Med Mol Morphol"},{"issue":"7","key":"1879_CR10","doi-asserted-by":"publisher","first-page":"e280","DOI":"10.1097\/MPH.0b013e31829182bb","volume":"35","author":"A Saito","year":"2013","unstructured":"Saito A, Taketani T, Kanai R, Kanagawa T, Kumori K, Yamamoto N et al (2013) A case with sacrococcygeal primitive myxoid mesenchymal tumor of infancy: a case report and review of the literature. J Pediatr Hematol Oncol 35(7):e280\u2013e282. https:\/\/doi.org\/10.1097\/MPH.0b013e31829182bb","journal-title":"J Pediatr Hematol Oncol"},{"issue":"7","key":"1879_CR11","doi-asserted-by":"publisher","first-page":"647","DOI":"10.1177\/1066896913509006","volume":"22","author":"NA Cipriani","year":"2014","unstructured":"Cipriani NA, Ryan DP, Nielsen GP (2014) Primitive myxoid mesenchymal tumor of infancy with rosettes: a new finding and literature review. Int J Surg Pathol 22(7):647\u2013651. https:\/\/doi.org\/10.1177\/1066896913509006","journal-title":"Int J Surg Pathol"},{"issue":"2","key":"1879_CR12","doi-asserted-by":"publisher","first-page":"e118","DOI":"10.1097\/MPH.0000000000000107","volume":"37","author":"MC Guilbert","year":"2015","unstructured":"Guilbert MC, Rougemont AL, Samson Y, Mac-Thiong JM, Fournet JC, Soglio DB (2015) Transformation of a primitive myxoid mesenchymal tumor of infancy to an undifferentiated sarcoma: a first reported case. J Pediatr Hematol Oncol 37(2):e118\u2013e120. https:\/\/doi.org\/10.1097\/MPH.0000000000000107","journal-title":"J Pediatr Hematol Oncol"},{"issue":"3","key":"1879_CR13","first-page":"310","volume":"44","author":"DW Cuthbertson","year":"2014","unstructured":"Cuthbertson DW, Caceres K, Hicks J, Friedman EM (2014) A cooperative approach to diagnosis of rare diseases: primitive myxoid mesenchymal tumor of infancy. Ann Clin Lab Sci 44(3):310\u2013316","journal-title":"Ann Clin Lab Sci"},{"issue":"3","key":"1879_CR14","doi-asserted-by":"publisher","first-page":"244","DOI":"10.2350\/15-05-1644-CR.1","volume":"19","author":"JH Foster","year":"2016","unstructured":"Foster JH, Vasudevan SA, John Hicks M, Schady D, Chintagumpala M (2016) Primitive myxoid mesenchymal tumor of infancy involving chest wall in an infant: a case report and clinicopathologic correlation. Pediatr Dev Pathol 19(3):244\u2013248. https:\/\/doi.org\/10.2350\/15-05-1644-CR.1","journal-title":"Pediatr Dev Pathol"},{"issue":"2","key":"1879_CR15","doi-asserted-by":"publisher","first-page":"374","DOI":"10.1038\/modpathol.2017.178","volume":"31","author":"T Santiago","year":"2018","unstructured":"Santiago T, Clay MR, Allen SJ, Orr BA (2018) Recurrent BCOR internal tandem duplication and BCOR or BCL6 expression distinguish primitive myxoid mesenchymal tumor of infancy from congenital infantile fibrosarcoma. Mod Pathol 31(2):374. https:\/\/doi.org\/10.1038\/modpathol.2017.178","journal-title":"Mod Pathol"},{"issue":"7","key":"1879_CR16","doi-asserted-by":"publisher","first-page":"868","DOI":"10.6004\/jnccn.2017.0124","volume":"15","author":"SL Cramer","year":"2017","unstructured":"Cramer SL, Li R, Ali S, Bradley JA, Kim HK, Pressey JG (2017) Successful treatment of recurrent primitive myxoid mesenchymal tumor of infancy with BCOR internal tandem duplication. J Natl Compr Canc Netw 15(7):868\u2013871. https:\/\/doi.org\/10.6004\/jnccn.2017.0124","journal-title":"J Natl Compr Canc Netw"},{"issue":"4","key":"1879_CR17","doi-asserted-by":"publisher","first-page":"e260","DOI":"10.1097\/MPH.0000000000000945","volume":"40","author":"D Chacon","year":"2018","unstructured":"Chacon D, Correa C, Luengas JP (2018) Mesenteric primitive myxoid mesenchymal tumor in a 7-month-old boy. J Pediatr Hematol Oncol 40(4):e260\u2013e262. https:\/\/doi.org\/10.1097\/MPH.0000000000000945","journal-title":"J Pediatr Hematol Oncol"},{"issue":"2","key":"1879_CR18","doi-asserted-by":"publisher","first-page":"363","DOI":"10.1007\/s00381-018-3964-x","volume":"35","author":"AA Saeed","year":"2019","unstructured":"Saeed AA, Riaz Q, Din NU, Altaf S (2019) Primitive myxoid mesenchymal tumor of infancy with brain metastasis: first reported case. Childs Nerv Syst 35(2):363\u2013368. https:\/\/doi.org\/10.1007\/s00381-018-3964-x","journal-title":"Childs Nerv Syst"},{"issue":"3","key":"1879_CR19","doi-asserted-by":"publisher","first-page":"163","DOI":"10.1097\/MPH.0000000000001764","volume":"42","author":"SD Asaftei","year":"2020","unstructured":"Asaftei SD, Campello A, Tirtei E, Colombo S, Vallero S, Boffano M et al (2020) Management of unresectable metastatic primitive myxoid mesenchymal tumor of infancy: a case report and systematic review of the literature. J Pediatr Hematol Oncol 42(3):163\u2013169. https:\/\/doi.org\/10.1097\/MPH.0000000000001764","journal-title":"J Pediatr Hematol Oncol"},{"issue":"6","key":"1879_CR20","doi-asserted-by":"publisher","first-page":"458","DOI":"10.1016\/j.annpat.2021.12.005","volume":"42","author":"MA Essaoudi","year":"2022","unstructured":"Essaoudi MA, Khmou M, Elkababri M, Rouas L, Hessissen L, Lamalmi N (2022) Primitive myxoid mesenchymal tumor of infancy: case report and review of the literature. Ann Pathol 42(6):458\u2013461. https:\/\/doi.org\/10.1016\/j.annpat.2021.12.005","journal-title":"Ann Pathol"},{"issue":"Suppl 2","key":"1879_CR21","doi-asserted-by":"publisher","first-page":"929","DOI":"10.1007\/s12070-020-01995-7","volume":"74","author":"KS Sachdeva","year":"2022","unstructured":"Sachdeva KS, Shrivastav V (2022) Primitive myxoid mesenchymal tumour of nose. Indian J Otolaryngol Head Neck Surg 74(Suppl 2):929\u2013936. https:\/\/doi.org\/10.1007\/s12070-020-01995-7","journal-title":"Indian J Otolaryngol Head Neck Surg"},{"issue":"2","key":"1879_CR22","doi-asserted-by":"publisher","first-page":"e90","DOI":"10.1016\/j.jcjo.2022.07.002","volume":"58","author":"F Taimur","year":"2023","unstructured":"Taimur F, Akbar M, Manzoor A, Afghani T, Asif M (2023) Primitive myxoid mesenchymal tumours of infancy: first case surrounding the optic nerve. Can J Ophthalmol 58(2):e90\u2013e92. https:\/\/doi.org\/10.1016\/j.jcjo.2022.07.002","journal-title":"Can J Ophthalmol"},{"issue":"8","key":"1879_CR23","doi-asserted-by":"publisher","first-page":"e980","DOI":"10.1097\/MPH.0000000000002721","volume":"45","author":"D Raved","year":"2023","unstructured":"Raved D, Villani A, Hopyan S, Chen H, German A, Gupta AA (2023) Primitive myxoid mesenchymal tumor of infancy with brain metastasis case report and literature review. J Pediatr Hematol Oncol 45(8):e980\u2013e983. https:\/\/doi.org\/10.1097\/MPH.0000000000002721","journal-title":"J Pediatr Hematol Oncol"},{"issue":"4","key":"1879_CR24","doi-asserted-by":"publisher","first-page":"932","DOI":"10.4103\/ijpm.ijpm_471_23","volume":"67","author":"M Goswami","year":"2024","unstructured":"Goswami M (2024) Primitive myxoid mesenchymal tumor of infancy, an enigmatic entity: a case report. Indian J Pathol Microbiol 67(4):932\u2013935. https:\/\/doi.org\/10.4103\/ijpm.ijpm_471_23","journal-title":"Indian J Pathol Microbiol"},{"issue":"3","key":"1879_CR25","doi-asserted-by":"publisher","first-page":"596","DOI":"10.4103\/ijpm.ijpm_728_23","volume":"68","author":"S Yener","year":"2025","unstructured":"Yener S, Tosun \u0130, Y\u0131ld\u0131z ZA, Zemheri IE, \u0130l\u00e7e Z (2025) Primitive myxoid mesenchymal tumor of infancy presenting with an abdominal and thoracic mass misdiagnosed as neuroblastoma: a case report. Indian J Pathol Microbiol 68(3):596\u2013599. https:\/\/doi.org\/10.4103\/ijpm.ijpm_728_23","journal-title":"Indian J Pathol Microbiol"},{"issue":"12","key":"1879_CR26","doi-asserted-by":"publisher","first-page":"1670","DOI":"10.1097\/PAS.0000000000000697","volume":"40","author":"YC Kao","year":"2016","unstructured":"Kao YC, Sung YS, Zhang L, Jungbluth AA, Huang SC, Argani P et al (2016) BCOR overexpression is a highly sensitive marker in round cell sarcomas with BCOR genetic abnormalities. Am J Surg Pathol 40(12):1670\u20131678. https:\/\/doi.org\/10.1097\/PAS.0000000000000697","journal-title":"Am J Surg Pathol"},{"issue":"11","key":"1879_CR27","doi-asserted-by":"publisher","first-page":"1291","DOI":"10.1097\/PAS.0000000000002112","volume":"47","author":"S Chen","year":"2023","unstructured":"Chen S, Gallant S, Cunningham MJ, Robson CD, Church AJ, Perez-Atayde AR et al (2023) CTNNB1 and APC mutations in sinonasal myxoma: expanding the spectrum of tumors driven by WNT\/\u03b2-catenin pathway. Am J Surg Pathol 47(11):1291\u20131300. https:\/\/doi.org\/10.1097\/PAS.0000000000002112","journal-title":"Am J Surg Pathol"},{"issue":"3\u20134","key":"1879_CR28","doi-asserted-by":"publisher","first-page":"227","DOI":"10.1615\/critrevoncog.2015013800","volume":"20","author":"JF Shern","year":"2015","unstructured":"Shern JF, Yohe ME, Khan J (2015) Pediatric rhabdomyosarcoma. Crit Rev Oncog 20(3\u20134):227\u2013243. https:\/\/doi.org\/10.1615\/critrevoncog.2015013800","journal-title":"Crit Rev Oncog"}],"container-title":["Head and Neck Pathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12105-025-01879-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s12105-025-01879-8","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12105-025-01879-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,1,11]],"date-time":"2026-01-11T20:01:37Z","timestamp":1768161697000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s12105-025-01879-8"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,1,8]]},"references-count":28,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2026,12]]}},"alternative-id":["1879"],"URL":"https:\/\/doi.org\/10.1007\/s12105-025-01879-8","relation":{},"ISSN":["1936-0568"],"issn-type":[{"value":"1936-0568","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,1,8]]},"assertion":[{"value":"6 November 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"17 December 2025","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"8 January 2026","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare no competing interests.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"This article does not contain any studies with human participants or animals performed by any of the authors.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical Approval"}},{"value":"This study has been approved by the Ethics Committee of Xi jing Hospital.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to Participate"}},{"value":"This article does not contain any identifiable images or data.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for Publication"}}],"article-number":"10"}}