{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,29]],"date-time":"2026-05-29T13:13:15Z","timestamp":1780060395931,"version":"3.54.0"},"reference-count":32,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2026,5,29]],"date-time":"2026-05-29T00:00:00Z","timestamp":1780012800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2026,5,29]],"date-time":"2026-05-29T00:00:00Z","timestamp":1780012800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"DOI":"10.13039\/501100006416","name":"Universidade Estadual De Campinas","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100006416","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Head and Neck Pathol"],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>Warthin-like mucoepidermoid carcinoma (WL-MEC) is a low-grade variant of mucoepidermoid carcinoma (MEC), characterized by a multicystic growth pattern and dense lymphoid stroma, histologically mimicking Warthin tumor (WT). Few cases have been reported, limiting understanding of this variant. We aimed to provide a comprehensive clinical, histopathologic, and molecular analysis of new WL-MEC cases.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods and Results<\/jats:title>\n                    <jats:p>\n                      Fourteen WL-MEC cases from Brazil, Guatemala, and Mexico were analyzed. Clinicopathologic features (patient demographics, tumor location, AFIP grading, follow-up, recurrence), histological characteristics (architectural patterns, inflammatory infiltrate, epithelial components, invasion), and immunohistochemical profiles (CK5\/6, p63, p40, CK7, CK14, Ki67, HER2) were assessed.\n                      <jats:italic>MAML2<\/jats:italic>\n                      generearrangements and\n                      <jats:italic>HER2<\/jats:italic>\n                      amplification were evaluated by fluorescence in situ hybridization (FISH). All 14 cases showed\n                      <jats:italic>MAML2<\/jats:italic>\n                      rearrangement (100%), confirming the diagnosis, while\n                      <jats:italic>HER2<\/jats:italic>\n                      amplification was absent in all 9 cases tested.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>\n                      This study provides new insights into the clinicopathological and molecular features of WL-MEC, confirming its typical presentation (parotid gland, middle-aged females), low-grade behavior, and favorable prognosis after surgical excision. Detection of\n                      <jats:italic>MAML2<\/jats:italic>\n                      rearrangement is a valuable diagnostic tool for distinguishing WL-MEC from WT.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1007\/s12105-026-01896-1","type":"journal-article","created":{"date-parts":[[2026,5,29]],"date-time":"2026-05-29T12:44:47Z","timestamp":1780058687000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Characterizing Warthin-Like Mucoepidermoid Carcinoma: Clinicopathologic Features and MAML2 Rearrangements in 14 Latin American Cases"],"prefix":"10.1007","volume":"20","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2720-5826","authenticated-orcid":false,"given":"Ricardo Anderson","family":"de Oliveira Vasconcelos","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0295-7925","authenticated-orcid":false,"given":"Isaac Santos","family":"Ara\u00fajo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2053-8097","authenticated-orcid":false,"given":"Luiz Miguel","family":"Ferreira","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0079-2373","authenticated-orcid":false,"given":"Jo\u00e3o Paulo Gon\u00e7alves","family":"de Paiva","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0377-0441","authenticated-orcid":false,"given":"Igor Lima","family":"Fernandes","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3790-4479","authenticated-orcid":false,"given":"Lucas Faria","family":"Abrahao-Machado","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3792-6758","authenticated-orcid":false,"given":"Claudia Haydee Sarai","family":"Caro-S\u00e1nchez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9459-7351","authenticated-orcid":false,"given":"Ana Mar\u00eda","family":"Cano-Valdez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8956-6016","authenticated-orcid":false,"given":"Adalberto","family":"Mosqueda-Taylor","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6861-6640","authenticated-orcid":false,"given":"Ciro Dantas","family":"Soares","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,5,29]]},"reference":[{"issue":"2","key":"1896_CR1","doi-asserted-by":"publisher","first-page":"368504231179816","DOI":"10.1177\/00368504231179816","volume":"106","author":"L Yan","year":"2023","unstructured":"Yan L, Xu J, Liu L et al (2023) Warthin-like mucoepidermoid carcinoma of the parotid gland: clinicopathological observation and literature review. Sci Prog 106(2):368504231179816. https:\/\/doi.org\/10.1177\/00368504231179816","journal-title":"Sci Prog"},{"issue":"11","key":"1896_CR2","doi-asserted-by":"publisher","first-page":"1479","DOI":"10.1097\/PAS.0000000000000507","volume":"39","author":"K Ishibashi","year":"2015","unstructured":"Ishibashi K, Ito Y, Masaki A et al (2015) Warthin-like mucoepidermoid carcinoma. Am J Surg Pathol 39(11):1479\u20131487. https:\/\/doi.org\/10.1097\/PAS.0000000000000507","journal-title":"Am J Surg Pathol"},{"key":"1896_CR3","doi-asserted-by":"publisher","first-page":"55","DOI":"10.1007\/s12105-025-01778-y","volume":"19","author":"RA de Oliveira Vasconcelos","year":"2025","unstructured":"de Oliveira Vasconcelos RA, Ara\u00fajo IS, Ferreira LM et al (2025) Clinicopathological analysis of salivary glands warthin-like mucoepidermoid carcinoma: a systematic review. Head Neck Pathol 19:55. https:\/\/doi.org\/10.1007\/s12105-025-01778-y","journal-title":"Head Neck Pathol"},{"issue":"4","key":"1896_CR4","doi-asserted-by":"publisher","first-page":"923","DOI":"10.1007\/s12105-020-01156-w","volume":"14","author":"EV Daoud","year":"2020","unstructured":"Daoud EV, McLean-Holden AC, Pfeifer CM et al (2020) Pediatric Warthin-like mucoepidermoid carcinoma: report of two cases with one persistent\/recurrent as conventional mucoepidermoid carcinoma. Head Neck Pathol 14(4):923\u2013928. https:\/\/doi.org\/10.1007\/s12105-020-01156-w","journal-title":"Head Neck Pathol"},{"issue":"2","key":"1896_CR5","doi-asserted-by":"publisher","first-page":"e24873","DOI":"10.1016\/j.heliyon.2024.e24873","volume":"10","author":"X Wang","year":"2024","unstructured":"Wang X, Liu L, He H et al (2024) MAML2 gene rearrangement occurs in all Warthin-like mucoepidermoid carcinoma: a reappraisal in a series of 29 cases. Heliyon 10(2):e24873. https:\/\/doi.org\/10.1016\/j.heliyon.2024.e24873","journal-title":"Heliyon"},{"issue":"4","key":"1896_CR6","doi-asserted-by":"publisher","first-page":"e2019122","DOI":"10.4322\/acr.2019.122","volume":"9","author":"V Balasubiramaniyan","year":"2019","unstructured":"Balasubiramaniyan V, Sultania M, Sable M et al (2019) Warthin-like mucoepidermoid carcinoma of the parotid gland: a diagnostic and therapeutic dilemma. Autopsy Case Rep 9(4):e2019122. https:\/\/doi.org\/10.4322\/acr.2019.122","journal-title":"Autopsy Case Rep"},{"issue":"3","key":"1896_CR7","doi-asserted-by":"publisher","first-page":"378","DOI":"10.1111\/his.12183","volume":"63","author":"T Nakano","year":"2013","unstructured":"Nakano T, Yamamoto H, Hashimoto K et al (2013) HER2 and EGFR gene copy number alterations are predominant in high-grade salivary mucoepidermoid carcinoma irrespective of MAML2 fusion status. Histopathology 63(3):378\u2013392. https:\/\/doi.org\/10.1111\/his.12183","journal-title":"Histopathology"},{"issue":"22","key":"1896_CR8","doi-asserted-by":"publisher","first-page":"3867","DOI":"10.1200\/JCO.22.02864","volume":"41","author":"AC Wolff","year":"2023","unstructured":"Wolff AC, Somerfield MR, Dowsett M et al (2023) Human Epidermal growth factor receptor 2 testing in breast cancer: ASCO college of American Pathologists guideline update. J Clin Oncol 41(22):3867\u20133872. https:\/\/doi.org\/10.1200\/JCO.22.02864","journal-title":"J Clin Oncol"},{"issue":"3","key":"1896_CR9","doi-asserted-by":"publisher","first-page":"366","DOI":"10.1001\/jamaoncol.2018.6012","volume":"5","author":"MF Press","year":"2019","unstructured":"Press MF, Seoane JA, Curtis C et al (2019) Assessment of ERBB2\/HER2 Status in HER2-Equivocal Breast Cancers by FISH and 2013\/2014 ASCO-CAP Guidelines. JAMA Oncol 5(3):366\u2013375. https:\/\/doi.org\/10.1001\/jamaoncol.2018.6012","journal-title":"JAMA Oncol"},{"issue":"10","key":"1896_CR10","doi-asserted-by":"publisher","first-page":"2277","DOI":"10.1002\/hed.27099","volume":"44","author":"R Fisher","year":"2022","unstructured":"Fisher R, Ronen O (2022) Cytologic diagnosis of parotid gland Warthin tumor: Systematic review and meta-analysis. Head Neck 44(10):2277\u20132287. https:\/\/doi.org\/10.1002\/hed.27099","journal-title":"Head Neck"},{"key":"1896_CR11","doi-asserted-by":"publisher","unstructured":"Alqahtani ASM, Alaidaroos OZA, Alsibani A et al (2024) New trends of warthin tumor management: a systematic review of nonsurgical modalities. Ear Nose Throat J 1455613241260969. https:\/\/doi.org\/10.1177\/01455613241260969","DOI":"10.1177\/01455613241260969"},{"issue":"1","key":"1896_CR12","doi-asserted-by":"publisher","first-page":"131","DOI":"10.1007\/s10006-023-01156-4","volume":"16","author":"P Bonavolont\u00e0","year":"2023","unstructured":"Bonavolont\u00e0 P, Germano C, Committeri U et al (2023) Surgical management of Warthin tumor: long-term follow-up of 224 patients from 2002 to 2018. Oral Maxillofac Surg 16(1):131\u2013136. https:\/\/doi.org\/10.1007\/s10006-023-01156-4","journal-title":"Oral Maxillofac Surg"},{"issue":"6","key":"1896_CR13","doi-asserted-by":"publisher","first-page":"713","DOI":"10.1016\/j.jormas.2020.06.003","volume":"121","author":"A Peraza","year":"2020","unstructured":"Peraza A, G\u00f3mez R, Beltran J et al (2020) Mucoepidermoid carcinoma: an update and review of the literature. J Stomatol Oral Maxillofac Surg 121(6):713\u2013720. https:\/\/doi.org\/10.1016\/j.jormas.2020.06.003","journal-title":"J Stomatol Oral Maxillofac Surg"},{"issue":"1","key":"1896_CR14","doi-asserted-by":"publisher","first-page":"130","DOI":"10.1097\/PAS.0000000000000932","volume":"42","author":"JA Bishop","year":"2018","unstructured":"Bishop JA, Cowan ML, Shum CH et al (2018) MAML2 rearrangements in variant forms of mucoepidermoid carcinoma: ancillary diagnostic testing for the ciliated and warthin-like variants. Am J Surg Pathol 42(1):130\u2013136. https:\/\/doi.org\/10.1097\/PAS.0000000000000932","journal-title":"Am J Surg Pathol"},{"issue":"1","key":"1896_CR15","doi-asserted-by":"publisher","first-page":"179","DOI":"10.1007\/s12105-022-01422-z","volume":"16","author":"JA Bishop","year":"2022","unstructured":"Bishop JA (2022) Proceedings of the North American Society of Head and Neck Pathology, Los Angeles, CA, March 20, 2022: Emerging Entities in Salivary Gland Tumor Pathology. Head Neck Pathol 16(1):179\u2013189. https:\/\/doi.org\/10.1007\/s12105-022-01422-z","journal-title":"Head Neck Pathol"},{"key":"1896_CR16","doi-asserted-by":"publisher","first-page":"30149","DOI":"10.1038\/srep30149","volume":"6","author":"C Yu","year":"2016","unstructured":"Yu C, Song Z, Xiao Z, Lin Q, Dong X (2016) Mucoepidermoid carcinoma arising in Warthin\u2019s tumor of the parotid gland: Clinicopathological characteristics and immunophenotypes. Sci Rep 6:30149. https:\/\/doi.org\/10.1038\/srep30149","journal-title":"Sci Rep"},{"issue":"5","key":"1896_CR17","doi-asserted-by":"publisher","first-page":"912","DOI":"10.3390\/cancers16050912","volume":"16","author":"R Aoki","year":"2024","unstructured":"Aoki R, Tanaka T (2024) Pathogenesis of Warthin\u2019s Tumor: Neoplastic or Non-Neoplastic? Cancers 16(5):912. https:\/\/doi.org\/10.3390\/cancers16050912","journal-title":"Cancers"},{"issue":"2","key":"1896_CR18","doi-asserted-by":"publisher","first-page":"183","DOI":"10.1111\/his.15289","volume":"86","author":"RA Wolk","year":"2025","unstructured":"Wolk RA, Cipriani NA (2025) Update of newly-recognized salivary gland neoplasms: molecular and immunohistochemical findings and clinical importance. Histopathology 86(2):183\u2013198. https:\/\/doi.org\/10.1111\/his.15289","journal-title":"Histopathology"},{"key":"1896_CR19","doi-asserted-by":"publisher","first-page":"45","DOI":"10.1007\/s12105-024-01661-2","volume":"18","author":"JPG de Paiva","year":"2024","unstructured":"de Paiva JPG, Rold\u00e1n DG, Bezerra HKF et al (2024) Intraoral Salivary Gland Cystadenomas: A Case Series Study and Literature Review. Head Neck Pathol 18:45. https:\/\/doi.org\/10.1007\/s12105-024-01661-2","journal-title":"Head Neck Pathol"},{"issue":"1","key":"1896_CR20","doi-asserted-by":"publisher","first-page":"20","DOI":"10.1007\/s12105-024-01622-9","volume":"18","author":"N Katabi","year":"2024","unstructured":"Katabi N (2024) Oncocytoid Salivary Tumors: Differential Diagnosis and Utility of Newly Described Immunohistochemistry. Head Neck Pathol 18(1):20. https:\/\/doi.org\/10.1007\/s12105-024-01622-9","journal-title":"Head Neck Pathol"},{"issue":"9","key":"1896_CR21","doi-asserted-by":"publisher","first-page":"672","DOI":"10.1111\/jop.12438","volume":"45","author":"FP Fonseca","year":"2016","unstructured":"Fonseca FP, Bingle L, Santos-Silva AR et al (2016) Immunoexpression of HOXB7 and HOXB9 in salivary gland tumours. J Oral Pathol Med 45(9):672\u2013681. https:\/\/doi.org\/10.1111\/jop.12438","journal-title":"J Oral Pathol Med"},{"issue":"1","key":"1896_CR22","doi-asserted-by":"publisher","first-page":"143","DOI":"10.35787\/jimdc.v13i1.886","volume":"13","author":"N Sultan","year":"2024","unstructured":"Sultan N, Rasul F, Rizvi NZ et al (2024) Immunohistochemical expression of Ki-67 in malignant salivary glands tumors. J Islamabad Med Dent Coll 13(1):143\u2013150. https:\/\/doi.org\/10.35787\/jimdc.v13i1.886","journal-title":"J Islamabad Med Dent Coll"},{"issue":"12","key":"1896_CR23","doi-asserted-by":"publisher","first-page":"2001","DOI":"10.1016\/j.humpath.2011.02.028","volume":"42","author":"JJ Garc\u00eda","year":"2011","unstructured":"Garc\u00eda JJ, Hunt JL, Weinreb I, McHugh JB, Barnes EL, Cieply K, Dacic S, Seethala RR (2011) Fluorescence in situ hybridization for detection of MAML2 rearrangements in oncocytic mucoepidermoid carcinomas: utility as a diagnostic test. Hum Pathol 42(12):2001\u20132009. https:\/\/doi.org\/10.1016\/j.humpath.2011.02.028","journal-title":"Hum Pathol"},{"issue":"3","key":"1896_CR24","doi-asserted-by":"publisher","first-page":"393","DOI":"10.1007\/s00428-020-02798-5","volume":"477","author":"M Bie\u0144kowski","year":"2020","unstructured":"Bie\u0144kowski M, Kunc M, Iliszko M et al (2020) MAML2 rearrangement as a useful diagnostic marker discriminating between Warthin tumour and Warthin-like mucoepidermoid carcinoma. Virchows Arch 477(3):393\u2013400. https:\/\/doi.org\/10.1007\/s00428-020-02798-5","journal-title":"Virchows Arch"},{"issue":"8","key":"1896_CR25","doi-asserted-by":"publisher","first-page":"1106","DOI":"10.1097\/PAS.0b013e3181de3021","volume":"34","author":"RR Seethala","year":"2010","unstructured":"Seethala RR, Dacic S, Cieply K, Kelly LM, Nikiforova MN (2010) A reappraisal of the MECT1\/MAML2 translocation in salivary mucoepidermoid carcinomas. Am J Surg Pathol 34(8):1106\u20131121. https:\/\/doi.org\/10.1097\/PAS.0b013e3181de3021","journal-title":"Am J Surg Pathol"},{"issue":"8","key":"1896_CR26","doi-asserted-by":"publisher","first-page":"4322","DOI":"10.3390\/ijms23084322","volume":"23","author":"JC Thierauf","year":"2022","unstructured":"Thierauf JC, Farahani AA, Indave BI, Bard AZ, White VA, Smith CR, Marble H, Hyrcza MD, Chan JKC, Bishop J, Shi Q, Ely K, Agaimy A, Martinez-Lage M, Nose V, Rivera M, Nardi V, Dias-Santagata D, Garg S, Sadow P, Lennerz JK (2022) Diagnostic Value of MAML2 Rearrangements in Mucoepidermoid Carcinoma. Int J Mol Sci 23(8):4322. https:\/\/doi.org\/10.3390\/ijms23084322","journal-title":"Int J Mol Sci"},{"issue":"1","key":"1896_CR27","doi-asserted-by":"publisher","first-page":"29","DOI":"10.1002\/cdt3.55","volume":"9","author":"Y Zhu","year":"2023","unstructured":"Zhu Y, Li Y, Guo L, Li W, Mu J, Zhang H, Li X, Ying J, Lu H (2023) Clinicopathological practice in the differential diagnosis of mucoepidermoid carcinoma from neoplasms with mucinous component. Chronic Dis translational Med 9(1):29\u201338. https:\/\/doi.org\/10.1002\/cdt3.55","journal-title":"Chronic Dis translational Med"},{"key":"1896_CR28","doi-asserted-by":"publisher","first-page":"693394","DOI":"10.3389\/fonc.2021.693394","volume":"11","author":"K Egebjerg","year":"2021","unstructured":"Egebjerg K, Harwood CD, Woller NC et al (2021) HER2 positivity in histological subtypes of salivary gland carcinoma: a systematic review and meta-analysis. Front Oncol 11:693394. https:\/\/doi.org\/10.3389\/fonc.2021.693394","journal-title":"Front Oncol"},{"issue":"3","key":"1896_CR29","doi-asserted-by":"publisher","first-page":"244","DOI":"10.1159\/000521134","volume":"66","author":"K Basak","year":"2022","unstructured":"Basak K, Mericoz CA, Firat P (2022) Warthin-like Mucoepidermoid carcinoma: a morphological Spectrum\u2013a report of 3 cases with histological and cytological findings and review of the literature. Acta Cytol 66(3):244\u2013252. https:\/\/doi.org\/10.1159\/000521134","journal-title":"Acta Cytol"},{"issue":"4","key":"1896_CR30","doi-asserted-by":"publisher","first-page":"e57","DOI":"10.1016\/j.oooo.2023.11.009","volume":"137","author":"R Bock","year":"2024","unstructured":"Bock R, Molony P, Conn B (2024) Primary intranodal Warthin-like variant of mucoepidermoid carcinoma. Oral Surg Oral Med Oral Pathol Oral Radiol 137(4):e57\u2013e62. https:\/\/doi.org\/10.1016\/j.oooo.2023.11.009","journal-title":"Oral Surg Oral Med Oral Pathol Oral Radiol"},{"issue":"2","key":"1896_CR31","doi-asserted-by":"publisher","first-page":"128","DOI":"10.1001\/jamaoto.2021.3459","volume":"148","author":"M Hanson","year":"2022","unstructured":"Hanson M, McGill M, Mimica X, Eagan A, Hay A, Wu J, Cohen MA, Patel SG, Ganly I (2022) Evaluation of Surgical Margin Status in Patients With Salivary Gland Cancer. JAMA otolaryngology\u2013 head neck Surg 148(2):128\u2013138. https:\/\/doi.org\/10.1001\/jamaoto.2021.3459","journal-title":"JAMA otolaryngology\u2013 head neck Surg"},{"key":"1896_CR32","doi-asserted-by":"publisher","first-page":"39","DOI":"10.3389\/fsurg.2018.00039","volume":"5","author":"J Thielker","year":"2018","unstructured":"Thielker J, Grosheva M, Ihrler S et al (2018) Contemporary Management of Benign and Malignant Parotid Tumors. Front Surg 5:39. https:\/\/doi.org\/10.3389\/fsurg.2018.00039","journal-title":"Front Surg"}],"container-title":["Head and Neck Pathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12105-026-01896-1.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s12105-026-01896-1","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12105-026-01896-1.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,29]],"date-time":"2026-05-29T12:44:48Z","timestamp":1780058688000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s12105-026-01896-1"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,5,29]]},"references-count":32,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2026,12]]}},"alternative-id":["1896"],"URL":"https:\/\/doi.org\/10.1007\/s12105-026-01896-1","relation":{},"ISSN":["1936-0568"],"issn-type":[{"value":"1936-0568","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,5,29]]},"assertion":[{"value":"29 October 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"16 February 2026","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"29 May 2026","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare no competing interests.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"57"}}