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The central argument holds that the enduring therapeutic benefits of psychedelics emerge through a radical transformation in the structure of lived experience. Two prominent objections to the therapeutic value of mystical experience are examined and shown to rest on implicit Cartesian assumptions that obscure the embodied, situated character of human experience. Using Merleau-Ponty\u2019s concepts of the body-subject and the intentional arc, depression is analysed as a collapse of perceptual attunement and engagement with the world, while psychedelic-induced mystical experience is shown to instantiate the opposite structure, recalibrating the intentional arc and restoring pre-reflective meaning. A phenomenological analysis of the acute mystical experience substantiates this claim, before a final response to the objection that psychedelic experiences are merely hallucinatory, arguing, via Merleau-Ponty\u2019s account of perception as irreducible to passive reflection, that such experiences may still disclose meaningful dimensions of the world.<\/jats:p>","DOI":"10.1007\/s12124-026-10029-w","type":"journal-article","created":{"date-parts":[[2026,9,21]],"date-time":"2026-09-21T14:06:10Z","timestamp":1789999570000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Embodied Transformation: Psychedelic Therapy Through the Lens of Merleau-Ponty\u2019s Phenomenology"],"prefix":"10.1007","volume":"60","author":[{"given":"Zinet","family":"Ritschel","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brady","family":"Wagoner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,9,21]]},"reference":[{"key":"10029_CR1","doi-asserted-by":"publisher","first-page":"179","DOI":"10.1016\/j.neubiorev.2020.03.017","volume":"113","author":"JS Aday","year":"2020","unstructured":"Aday, J. 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