{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,13]],"date-time":"2026-05-13T05:34:49Z","timestamp":1778650489187,"version":"3.51.4"},"reference-count":24,"publisher":"Springer Science and Business Media LLC","issue":"7","license":[{"start":{"date-parts":[[2015,4,29]],"date-time":"2015-04-29T00:00:00Z","timestamp":1430265600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"funder":[{"name":"Scientific Research, (C) from the Ministry of Education","award":["23591806"],"award-info":[{"award-number":["23591806"]}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Ann Nucl Med"],"published-print":{"date-parts":[[2015,8]]},"DOI":"10.1007\/s12149-015-0980-8","type":"journal-article","created":{"date-parts":[[2015,4,28]],"date-time":"2015-04-28T06:04:01Z","timestamp":1430201041000},"page":"643-649","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Assessment of 99mTc-MIBI SPECT(\/CT) to monitor multidrug resistance-related proteins and apoptosis-related proteins in patients with ovarian cancer: a preliminary study"],"prefix":"10.1007","volume":"29","author":[{"given":"Seiji","family":"Kurata","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kimio","family":"Ushijima","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Akihiko","family":"Kawahara","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hayato","family":"Kaida","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kouichirou","family":"Kawano","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yasumitsu","family":"Hirose","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masayoshi","family":"Kage","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Toshiharu","family":"Kamura","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masatoshi","family":"Ishibashi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Toshi","family":"Abe","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2015,4,29]]},"reference":[{"key":"980_CR1","doi-asserted-by":"crossref","first-page":"9","DOI":"10.3322\/caac.21208","volume":"64","author":"R Siegel","year":"2014","unstructured":"Siegel R, Ma J, Zou Z, Jemal A. Cancer statistics, 2014. CA Cancer J Clin. 2014;64:9\u201329.","journal-title":"CA Cancer J Clin"},{"key":"980_CR2","doi-asserted-by":"crossref","first-page":"96","DOI":"10.1097\/GRF.0b013e31824b45da","volume":"55","author":"MA Bookman","year":"2012","unstructured":"Bookman MA. First-line chemotherapy in epithelial ovarian cancer. Clin Obstet Gynecol. 2012;55:96\u2013113.","journal-title":"Clin Obstet Gynecol"},{"key":"980_CR3","doi-asserted-by":"crossref","first-page":"5594","DOI":"10.1158\/1078-0432.CCR-08-0606","volume":"14","author":"SE Johnatty","year":"2008","unstructured":"Johnatty SE, Beesley J, Paul J, Fereday S, Spurdle AB, Webb PM, et al. ABCB1 (MDR 1) polymorphisms and progression-free survival among women with ovarian cancer following paclitaxel\/carboplatin chemotherapy. Clin Cancer Res. 2008;14:5594\u2013601.","journal-title":"Clin Cancer Res"},{"key":"980_CR4","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1146\/annurev.cb.08.110192.000435","volume":"8","author":"CF Higgins","year":"1992","unstructured":"Higgins CF. ABC transporters: from microorganisms to man. Annu Rev Cell Biol. 1992;8:67\u2013113.","journal-title":"Annu Rev Cell Biol"},{"key":"980_CR5","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1042\/bse0500209","volume":"50","author":"A Tamaki","year":"2011","unstructured":"Tamaki A, Ierano C, Szakacs G, Robey RW, Bates SE. The controversial role of ABC transporters in clinical oncology. Essays Biochem. 2011;50:209\u201332.","journal-title":"Essays Biochem"},{"key":"980_CR6","doi-asserted-by":"crossref","first-page":"13906","DOI":"10.1074\/jbc.M600869200","volume":"281","author":"A Rothnie","year":"2006","unstructured":"Rothnie A, Callaghan R, Deeley RG, Cole SP. Role of GSH in estrone sulfate binding and translocation by the multidrug resistance protein 1 (MRP1\/ABCC1). J Biol Chem. 2006;281:13906\u201314.","journal-title":"J Biol Chem"},{"key":"980_CR7","doi-asserted-by":"crossref","first-page":"2450","DOI":"10.1002\/(SICI)1097-0142(19990601)85:11<2450::AID-CNCR21>3.0.CO;2-U","volume":"85","author":"T Kamura","year":"1999","unstructured":"Kamura T, Yahata H, Amada S, Ogawa S, Sonoda T, Kobayashi H, et al. Is nuclear expression of Y box-binding protein-1 a new prognostic factor in ovarian serous adenocarcinoma? Cancer. 1999;85:2450\u20134.","journal-title":"Cancer"},{"key":"980_CR8","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1016\/j.ygyno.2004.01.040","volume":"93","author":"X Huang","year":"2004","unstructured":"Huang X, Ushijima K, Komai K, Takemoto Y, Motoshima S, Kamura T, et al. Co-expression of Y box-binding protein-1 and P-glycoprotein as a prognostic marker for survival in epithelial ovarian cancer. Gynecol Oncol. 2004;93:287\u201391.","journal-title":"Gynecol Oncol"},{"key":"980_CR9","first-page":"2798","volume":"5","author":"HJ Arts","year":"1999","unstructured":"Arts HJ, Katsaros D, de Vries EG, Massobrio M, Genta F, Danese S, et al. Drug resistance-associated markers P-glycoprotein, multidrug resistance-associated protein 1, multidrug resistance-associated protein 2, and lung resistance protein as prognostic factors in ovarian carcinoma. Clin Cancer Res. 1999;5:2798\u2013805.","journal-title":"Clin Cancer Res"},{"key":"980_CR10","first-page":"519","volume":"43","author":"M Mubashar","year":"2002","unstructured":"Mubashar M, Harrington KJ, Chaudhary KS, Lalani EL-N, Stamp GW, Sinnett D, et al. 99mTc-sestamibi imaging in the assessment of toremifene as a modulator of multidrug resistance in patients with breast cancer. J Nucl Med. 2002;43:519\u201325.","journal-title":"J Nucl Med"},{"key":"980_CR11","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1007\/s12149-007-0080-5","volume":"22","author":"XY Duan","year":"2008","unstructured":"Duan XY, Wang JS, Liu M, Guo YM. Technetium-99m-hexakis-2-methoxyisobutylisonitrile scintigraphy and multidrug resistance-related protein expression in human primary lung cancer. Ann Nucl Med. 2008;22:49\u201355.","journal-title":"Ann Nucl Med"},{"key":"980_CR12","doi-asserted-by":"crossref","first-page":"1785","DOI":"10.2967\/jnumed.109.064980","volume":"50","author":"E Saggiorato","year":"2009","unstructured":"Saggiorato E, Angusti T, Rosas R, Martinese M, Finessi M, Arecco F, et al. 99mTc-MIBI Imaging in the presurgical characterization of thyroid follicular neoplasms: relationship to multidrug resistance protein expression. J Nucl Med. 2009;50:1785\u201393.","journal-title":"J Nucl Med"},{"key":"980_CR13","doi-asserted-by":"crossref","first-page":"2435","DOI":"10.1002\/cncr.25802","volume":"117","author":"XS Wang","year":"2011","unstructured":"Wang XS, Zhang YJ, Liu XL, Zhou ZR, Hu CS, Eisbruch A. The role of technetium-99m methoxyisobutyl isonitrile scintigraphy in predicting the therapeutic effect of chemotherapy against nasopharyngeal carcinoma. Cancer. 2011;117:2435\u201341.","journal-title":"Cancer"},{"key":"980_CR14","first-page":"977","volume":"53","author":"D Piwnica-Worms","year":"1993","unstructured":"Piwnica-Worms D, Chiu ML, Budding M, Kronauge JF, Kramer RA, Croop JM. Functional imaging of multidrug-resistant P-glycoprotein with an organotechnetium complex. Cancer Res. 1993;53:977\u201384.","journal-title":"Cancer Res"},{"key":"980_CR15","doi-asserted-by":"crossref","first-page":"647","DOI":"10.1038\/nrc883","volume":"2","author":"S Cory","year":"2002","unstructured":"Cory S, Adams JM. The Bcl2 family: regulators of the cellular life-or-death switch. Nat Rev Cancer. 2002;2:647\u201356.","journal-title":"Nat Rev Cancer"},{"key":"980_CR16","doi-asserted-by":"crossref","first-page":"879","DOI":"10.1007\/s00259-003-1161-x","volume":"30","author":"S Vecchio Del","year":"2003","unstructured":"Del Vecchio S, Zannetti A, Aloj L, Carac\u00f2 C, Ciarmiello A, Salvatore M. Inhibition of early 99mTc-MIBI uptake by Bcl-2 anti-apoptotic protein overexpression in untreated breast carcinoma. Eur J Nucl Med Mol Imaging. 2003;30:879\u201387.","journal-title":"Eur J Nucl Med Mol Imaging"},{"key":"980_CR17","doi-asserted-by":"crossref","first-page":"405","DOI":"10.3892\/or_00000873","volume":"24","author":"A Kawahara","year":"2010","unstructured":"Kawahara A, Hattori S, Akiba J, Nakashima K, Taira T, Watari K, et al. Infiltration of thymidine phosphorylase-positive macrophages is closely associated with tumor angiogenesis and survival in intestinal type gastric cancer. Oncol Rep. 2010;24:405\u201315.","journal-title":"Oncol Rep"},{"key":"980_CR18","first-page":"309","volume":"29","author":"J Stelmach\u00f3w","year":"2008","unstructured":"Stelmach\u00f3w J, Timorek-Lemieszczuk A. Technetium-99m-sestamibi scintigraphy in gynecological cancer imaging. Eur J Gynaecol Oncol. 2008;29:309\u201312.","journal-title":"Eur J Gynaecol Oncol"},{"key":"980_CR19","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1042\/BJ20121323","volume":"449","author":"A Lasham","year":"2013","unstructured":"Lasham A, Print CG, Woolley AG, Dunn SE, Braithwaite AW. YB-1: oncoprotein, prognostic marker and therapeutic target? Biochem J. 2013;449:11\u201323.","journal-title":"Biochem J"},{"key":"980_CR20","doi-asserted-by":"crossref","first-page":"696","DOI":"10.1097\/MNM.0b013e3281f74d97","volume":"28","author":"A Yang","year":"2007","unstructured":"Yang A, Xue J, Li X, Yu Y, Deng H, Hu G, et al. Experimental and clinical observations of 99mTc-MIBI uptake correlate with P-glycoprotein expression in lung cancer. Nucl Med Commun. 2007;28:696\u2013703.","journal-title":"Nucl Med Commun"},{"key":"980_CR21","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1016\/S0304-3835(02)00590-6","volume":"190","author":"H Saji","year":"2003","unstructured":"Saji H, Toi M, Saji S, Koike M, Kohno K, Kuwano M. Nuclear expression of YB-1 protein correlates with P-glycoprotein expression in human breast carcinoma. Cancer Lett. 2003;190:191\u20137.","journal-title":"Cancer Lett"},{"key":"980_CR22","first-page":"1355","volume":"54","author":"S Arao","year":"1994","unstructured":"Arao S, Suwa H, Mandai M, Tashiro H, Miyazaki K, Okamura H, et al. Expression of multidrug resistance gene and localization of P-glycoprotein in human primary ovarian cancer. Cancer Res. 1994;54:1355\u20139.","journal-title":"Cancer Res"},{"key":"980_CR23","first-page":"228","volume":"39","author":"L Kostakoglu","year":"1998","unstructured":"Kostakoglu L, Kiratli P, Ruacan S, Hayran M, Emri S, Erg\u00fcn EL. Association of tumor washout rates and accumulation of technetium-99m-MIBI with expression of P-glycoprotein in lung cancer. J Nucl Med. 1998;39:228\u201334.","journal-title":"J Nucl Med"},{"key":"980_CR24","doi-asserted-by":"crossref","first-page":"836","DOI":"10.1007\/s00259-005-1840-x","volume":"32","author":"JL Moretti","year":"2005","unstructured":"Moretti JL, Hauet N, Caglar M, Rebillard O, Burak Z. To use MIBI or not to use MIBI? That is the question when assessing tumour cells. Eur J Nucl Med Mol Imaging. 2005;32:836\u201342.","journal-title":"Eur J Nucl Med Mol Imaging"}],"container-title":["Annals of Nuclear Medicine"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s12149-015-0980-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s12149-015-0980-8\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s12149-015-0980-8","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,6,2]],"date-time":"2019-06-02T04:41:29Z","timestamp":1559450489000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s12149-015-0980-8"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,4,29]]},"references-count":24,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2015,8]]}},"alternative-id":["980"],"URL":"https:\/\/doi.org\/10.1007\/s12149-015-0980-8","relation":{},"ISSN":["0914-7187","1864-6433"],"issn-type":[{"value":"0914-7187","type":"print"},{"value":"1864-6433","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,4,29]]}}}