{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,4]],"date-time":"2026-06-04T11:57:33Z","timestamp":1780574253546,"version":"3.54.1"},"reference-count":32,"publisher":"Springer Science and Business Media LLC","issue":"3","license":[{"start":{"date-parts":[[2021,1,2]],"date-time":"2021-01-02T00:00:00Z","timestamp":1609545600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2021,1,2]],"date-time":"2021-01-02T00:00:00Z","timestamp":1609545600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"funder":[{"DOI":"10.13039\/501100003625","name":"Ministry of Health and Welfare","doi-asserted-by":"publisher","award":["HI14C2768"],"award-info":[{"award-number":["HI14C2768"]}],"id":[{"id":"10.13039\/501100003625","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003625","name":"Ministry of Health and Welfare","doi-asserted-by":"publisher","award":["HI18C2383"],"award-info":[{"award-number":["HI18C2383"]}],"id":[{"id":"10.13039\/501100003625","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Ministry of Science and ICT","award":["2017M2A2A6A02020353"],"award-info":[{"award-number":["2017M2A2A6A02020353"]}]},{"name":"Ministry of Science and ICT","award":["2020M2D9A1094074"],"award-info":[{"award-number":["2020M2D9A1094074"]}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Ann Nucl Med"],"published-print":{"date-parts":[[2021,3]]},"DOI":"10.1007\/s12149-020-01561-9","type":"journal-article","created":{"date-parts":[[2021,1,2]],"date-time":"2021-01-02T10:03:09Z","timestamp":1609581789000},"page":"299-306","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Test\u2013retest reproducibility of dopamine transporter density measured with [18F]FP-CIT PET in patients with essential tremor and Parkinson\u2019s disease"],"prefix":"10.1007","volume":"35","author":[{"given":"Hye Joo","family":"Son","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jungsu S.","family":"Oh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Minyoung","family":"Oh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sang Ju","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seung Jun","family":"Oh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sun Ju","family":"Chung","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jae Seung","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2021,1,2]]},"reference":[{"key":"1561_CR1","doi-asserted-by":"publisher","first-page":"610","DOI":"10.1056\/NEJMoa1205158","volume":"368","author":"WM Schuepbach","year":"2013","unstructured":"Schuepbach WM, Rau J, Knudsen K, Volkmann J, Krack P, Timmermann L, et al. Neurostimulation for Parkinson\u2019s disease with early motor complications. N Engl J Med. 2013;368:610\u201322.","journal-title":"N Engl J Med"},{"key":"1561_CR2","doi-asserted-by":"publisher","first-page":"384","DOI":"10.1212\/01.wnl.0000247740.47667.03","volume":"68","author":"ER Dorsey","year":"2007","unstructured":"Dorsey ER, Constantinescu R, Thompson JP, Biglan KM, Holloway RG, Kieburtz K, et al. Projected number of people with Parkinson disease in the most populous nations, 2005 through 2030. Neurology. 2007;68:384\u20136.","journal-title":"Neurology"},{"key":"1561_CR3","doi-asserted-by":"publisher","first-page":"889","DOI":"10.1016\/S0896-6273(03)00568-3","volume":"39","author":"W Dauer","year":"2003","unstructured":"Dauer W, Przedborski S. Parkinson\u2019s disease: mechanisms and models. Neuron. 2003;39:889\u2013909.","journal-title":"Neuron"},{"key":"1561_CR4","doi-asserted-by":"publisher","first-page":"861","DOI":"10.1093\/brain\/awf080","volume":"125","author":"AJ Hughes","year":"2002","unstructured":"Hughes AJ, Daniel SE, Ben-Shlomo Y, Lees AJ. The accuracy of diagnosis of parkinsonian syndromes in a specialist movement disorder service. Brain. 2002;125:861\u201370.","journal-title":"Brain"},{"key":"1561_CR5","doi-asserted-by":"publisher","first-page":"181","DOI":"10.1136\/jnnp.55.3.181","volume":"55","author":"AJ Hughes","year":"1992","unstructured":"Hughes AJ, Daniel SE, Kilford L, Lees AJ. Accuracy of clinical diagnosis of idiopathic Parkinson\u2019s disease: a clinico-pathological study of 100 cases. J Neurol Neurosurg Psychiatry. 1992;55:181\u20134.","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"1561_CR6","first-page":"425","volume":"42","author":"JS Kim","year":"2008","unstructured":"Kim JS. Practical approach for the clinical use of dopamine transporter imaging. Nucl Med Mol Imaging. 2008;42:425\u201334.","journal-title":"Nucl Med Mol Imaging"},{"key":"1561_CR7","doi-asserted-by":"publisher","first-page":"1059","DOI":"10.1038\/sj.jcbfm.9600607","volume":"28","author":"J Hirvonen","year":"2008","unstructured":"Hirvonen J, Johansson J, Ter\u00e4s M, Oikonen V, Lumme V, Virsu P, et al. Measurement of striatal and extrastriatal dopamine transporter binding with high-resolution PET and [11C]PE2I: quantitative modeling and test-retest reproducibility. J Cereb Blood Flow Metab. 2008;28:1059\u201369.","journal-title":"J Cereb Blood Flow Metab"},{"key":"1561_CR8","doi-asserted-by":"publisher","first-page":"1025","DOI":"10.1007\/s00259-017-3645-0","volume":"44","author":"S Kaller","year":"2017","unstructured":"Kaller S, Rullmann M, Patt M, Becker GA, Luthardt J, Girbardt J, et al. Test-retest measurements of dopamine D(1)-type receptors using simultaneous PET\/MRI imaging. Eur J Nucl Med Mol Imaging. 2017;44:1025\u201332.","journal-title":"Eur J Nucl Med Mol Imaging"},{"key":"1561_CR9","doi-asserted-by":"publisher","first-page":"222","DOI":"10.1016\/j.pscychresns.2011.07.004","volume":"201","author":"CB Yeh","year":"2012","unstructured":"Yeh CB, Chou YH, Cheng CY, Lee MS, Wang JJ, Lee CH, et al. Reproducibility of brain dopamine transporter binding with Tc-99m TRODAT-1 SPECT in healthy young men. Psychiatry Res. 2012;201:222\u20135.","journal-title":"Psychiatry Res"},{"key":"1561_CR10","doi-asserted-by":"publisher","first-page":"10","DOI":"10.1016\/j.pscychresns.2016.10.007","volume":"258","author":"K Matsuoka","year":"2016","unstructured":"Matsuoka K, Yasuno F, Shinkai T, Miyasaka T, Takahashi M, Kiuchi K, et al. Test-retest reproducibility of extrastriatal binding with (123)I-FP-CIT SPECT in healthy male subjects. Psychiatry Res Neuroimaging. 2016;258:10\u20135.","journal-title":"Psychiatry Res Neuroimaging"},{"key":"1561_CR11","doi-asserted-by":"publisher","first-page":"574","DOI":"10.1007\/s00259-012-2312-8","volume":"40","author":"F Kodaka","year":"2013","unstructured":"Kodaka F, Ito H, Kimura Y, Fujie S, Takano H, Fujiwara H, et al. Test-retest reproducibility of dopamine D2\/3 receptor binding in human brain measured by PET with [11C]MNPA and [11C]raclopride. Eur J Nucl Med Mol Imaging. 2013;40:574\u20139.","journal-title":"Eur J Nucl Med Mol Imaging"},{"key":"1561_CR12","doi-asserted-by":"publisher","first-page":"609","DOI":"10.1007\/BF02984583","volume":"18","author":"T Tsuchida","year":"2004","unstructured":"Tsuchida T, Ballinger JR, Vines D, Kim YJ, Utsunomiya K, Lang AE, et al. Reproducibility of dopamine transporter density measured with 123I-FPCIT SPECT in normal control and Parkinson\u2019s disease patients. Ann Nucl Med. 2004;18:609\u201316.","journal-title":"Ann Nucl Med"},{"key":"1561_CR13","first-page":"207","volume":"45","author":"WJ Hwang","year":"2004","unstructured":"Hwang WJ, Yao WJ, Wey SP, Ting G. Reproducibility of 99mTc-TRODAT-1 SPECT measurement of dopamine transporters in Parkinson\u2019s disease. J Nucl Med. 2004;45:207\u201313.","journal-title":"J Nucl Med"},{"issue":"Suppl 3","key":"1561_CR14","first-page":"2","volume":"13","author":"G Deuschl","year":"1998","unstructured":"Deuschl G, Bain P, Brin M. Consensus statement of the movement disorder society on tremor. Ad hoc scientific committee. Mov Disord. 1998;13(Suppl 3):2\u201323.","journal-title":"Mov Disord"},{"issue":"3","key":"1561_CR15","doi-asserted-by":"publisher","first-page":"181","DOI":"10.1136\/jnnp.55.3.181","volume":"55","author":"AJ Hughes","year":"1992","unstructured":"Hughes AJ, Daniel SE, Kilford L, Lees AJ. Accuracy of clinical diagnosis of idiopathic Parkinson\u2019s disease: a clinico-pathological study of 100 cases. J Neurol Neurosurg Psychiatry. 1992;55(3):181\u20134.","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"1561_CR16","doi-asserted-by":"publisher","first-page":"345","DOI":"10.1016\/j.nucmedbio.2007.02.007","volume":"34","author":"SJ Lee","year":"2007","unstructured":"Lee SJ, Oh SJ, Chi DY, Kang SH, Kil HS, Kim JS, et al. One-step high-radiochemical-yield synthesis of [18F]FP-CIT using a protic solvent system. Nucl Med Biol. 2007;34:345\u201351.","journal-title":"Nucl Med Biol"},{"key":"1561_CR17","doi-asserted-by":"publisher","first-page":"13","DOI":"10.1186\/s13550-018-0366-8","volume":"8","author":"R Baumgartner","year":"2018","unstructured":"Baumgartner R, Joshi A, Feng D, Zanderigo F, Ogden RT. Statistical evaluation of test-retest studies in PET brain imaging. EJNMMI Res. 2018;8:13.","journal-title":"EJNMMI Res"},{"key":"1561_CR18","doi-asserted-by":"publisher","first-page":"231","DOI":"10.1593\/tlo.09268","volume":"2","author":"HX Barnhart","year":"2009","unstructured":"Barnhart HX, Barboriak DP. Applications of the repeatability of quantitative imaging biomarkers: a review of statistical analysis of repeat data sets. Transl Oncol. 2009;2:231\u20135.","journal-title":"Transl Oncol"},{"key":"1561_CR19","doi-asserted-by":"publisher","first-page":"1195","DOI":"10.2307\/2532835","volume":"52","author":"H Quan","year":"1996","unstructured":"Quan H, Shih WJ. Assessing reproducibility by the within-subject coefficient of variation with random effects models. Biometrics. 1996;52:1195\u2013203.","journal-title":"Biometrics"},{"key":"1561_CR20","first-page":"147","volume-title":"Statistical methods","author":"GW Snedecor","year":"1989","unstructured":"Snedecor GW, Cochran WG. Specific indices of interater reliability. In: Snedecor GW, Cochran WG, editors. Statistical methods. Ames, IA: Iowa State University Press; 1989. p. 147\u201356."},{"key":"1561_CR21","first-page":"1453","volume":"38","author":"JP Seibyl","year":"1997","unstructured":"Seibyl JP, Marek K, Sheff K, Baldwin RM, Zoghbi S, Zea-Ponce Y, et al. Test\/retest reproducibility of iodine-123-betaCIT SPECT brain measurement of dopamine transporters in Parkinson\u2019s patients. J Nucl Med. 1997;38:1453\u20139.","journal-title":"J Nucl Med"},{"key":"1561_CR22","first-page":"1879","volume":"39","author":"J Booij","year":"1998","unstructured":"Booij J, Habraken JB, Bergmans P, Tissingh G, Winogrodzka A, Wolters EC, et al. Imaging of dopamine transporters with iodine-123-FP-CIT SPECT in healthy controls and patients with Parkinson\u2019s disease. J Nucl Med. 1998;39:1879\u201384.","journal-title":"J Nucl Med"},{"key":"1561_CR23","first-page":"865","volume-title":"The fourth generation of progress","author":"RT Malison","year":"1995","unstructured":"Malison RT, Laruelle M, Innis RB. Positron and single photon emission tomography: principles and applications in psychopharmacology. In: Bloom FE, Kupfer DJ, editors. The fourth generation of progress. New York, NY: Raven Press; 1995. p. 865."},{"key":"1561_CR24","first-page":"1","volume":"38","author":"S Asenbaum","year":"1997","unstructured":"Asenbaum S, Br\u00fccke T, Pirker W, Podreka I, Angelberger P, Wenger S, et al. Imaging of dopamine transporters with iodine-123-beta-CIT and SPECT in Parkinson\u2019s disease. J Nucl Med. 1997;38:1\u20136.","journal-title":"J Nucl Med"},{"key":"1561_CR25","first-page":"753","volume":"40","author":"J Booij","year":"1999","unstructured":"Booij J, Hemelaar TG, Speelman JD, de Bruin K, Janssen AG, van Royen EA. One-day protocol for imaging of the nigrostriatal dopaminergic pathway in Parkinson\u2019s disease by [123I]FPCIT SPECT. J Nucl Med. 1999;40:753\u201361.","journal-title":"J Nucl Med"},{"key":"1561_CR26","first-page":"1521","volume":"39","author":"K Kazumata","year":"1998","unstructured":"Kazumata K, Dhawan V, Chaly T, Antonini A, Margouleff C, Belakhlef A, et al. Dopamine transporter imaging with fluorine-18-FPCIT and PET. J Nucl Med. 1998;39:1521\u201330.","journal-title":"J Nucl Med"},{"key":"1561_CR27","doi-asserted-by":"publisher","first-page":"1199","DOI":"10.1038\/jcbfm.2015.53","volume":"35","author":"K Alakurtti","year":"2015","unstructured":"Alakurtti K, Johansson JJ, Joutsa J, Laine M, B\u00e4ckman L, Nyberg L, et al. Long-term test-retest reliability of striatal and extrastriatal dopamine D2\/3 receptor binding: study with [(11)C]raclopride and high-resolution PET. J Cereb Blood Flow Metab. 2015;35:1199\u2013205.","journal-title":"J Cereb Blood Flow Metab"},{"key":"1561_CR28","doi-asserted-by":"publisher","first-page":"524","DOI":"10.1016\/j.neuroimage.2009.12.058","volume":"50","author":"A Egerton","year":"2010","unstructured":"Egerton A, Demjaha A, McGuire P, Mehta MA, Howes OD. The test-retest reliability of 18F-DOPA PET in assessing striatal and extrastriatal presynaptic dopaminergic function. Neuroimage. 2010;50:524\u201331.","journal-title":"Neuroimage"},{"key":"1561_CR29","doi-asserted-by":"publisher","first-page":"361","DOI":"10.1016\/S0733-8619(18)30215-9","volume":"10","author":"WR Gibb","year":"1992","unstructured":"Gibb WR. Neuropathology of Parkinson\u2019s disease and related syndromes. Neurol Clin. 1992;10:361\u201376.","journal-title":"Neurol Clin"},{"key":"1561_CR30","doi-asserted-by":"publisher","first-page":"231","DOI":"10.1097\/MNM.0000000000000052","volume":"35","author":"M Suzuki","year":"2014","unstructured":"Suzuki M, Ito H, Kodaka F, Takano H, Kimura Y, Fujiwara H, et al. Reproducibility of PET measurement for presynaptic dopaminergic functions using L-[\u03b2-(11)C]DOPA and [(18)F]FE-PE2I in humans. Nucl Med Commun. 2014;35:231\u20137.","journal-title":"Nucl Med Commun"},{"key":"1561_CR31","doi-asserted-by":"publisher","first-page":"1397","DOI":"10.1038\/sj.jcbfm.9600439","volume":"27","author":"M Yaqub","year":"2007","unstructured":"Yaqub M, Boellaard R, van Berckel BN, Ponsen MM, Lubberink M, Windhorst AD, et al. Quantification of dopamine transporter binding using [18F]FP-beta-CIT and positron emission tomography. J Cereb Blood Flow Metab. 2007;27:1397\u2013406.","journal-title":"J Cereb Blood Flow Metab"},{"key":"1561_CR32","doi-asserted-by":"publisher","first-page":"621","DOI":"10.1097\/00019442-200411000-00008","volume":"12","author":"SA Gardiner","year":"2004","unstructured":"Gardiner SA, Morrison MF, Mozley PD, Mozley LH, Brensinger C, Bilker W, et al. Pilot study on the effect of estrogen replacement therapy on brain dopamine transporter availability in healthy, postmenopausal women. Am J Geriatr Psychiatry. 2004;12:621\u201330.","journal-title":"Am J Geriatr Psychiatry"}],"container-title":["Annals of Nuclear Medicine"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s12149-020-01561-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s12149-020-01561-9\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s12149-020-01561-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,2,23]],"date-time":"2021-02-23T15:25:51Z","timestamp":1614093951000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s12149-020-01561-9"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,1,2]]},"references-count":32,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2021,3]]}},"alternative-id":["1561"],"URL":"https:\/\/doi.org\/10.1007\/s12149-020-01561-9","relation":{},"ISSN":["0914-7187","1864-6433"],"issn-type":[{"value":"0914-7187","type":"print"},{"value":"1864-6433","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,1,2]]},"assertion":[{"value":"29 September 2020","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"29 November 2020","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"2 January 2021","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with ethical standards"}},{"value":"The study has been approved by the Asan Medical Center institutional review board (2018-0183), and all patients signed an informed consent form.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}}]}}